metabolism powerpoint

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    METABOLISM

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    Look at the picture !

    What are theydoing?

    What must they

    have to do that?

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    Energy

    Energy is the capacity of a

    physical system to perform work

    Forms of Energy

    Is the capacity to cause change

    Exists in various forms, of whichsome can perform work

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    The First Law ofThermodynamics

    According to the first law ofthermodynamics

    Energy can be transferred andtransformed

    Energy cannot be created ordestroyed

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    Where can they get it?

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    They getenergy fromfood

    How can foodbe changedinto energy?

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    Food changed into energy by

    one of the metabolismprocess.

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    METABOLISM

    DIVIDE INTO

    FACTORS

    ANABOLISM

    CATABOLISM

    ENZYMES

    SUBSTRATE

    ATP

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    METABOLISM

    Metabolism is the

    set of chemical

    reactions that occur

    in living organisms

    to maintain life.

    Metabolism is usually

    divided into two

    categories:

    1. Catabolism

    2. Anabolism

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    Catabolism

    - is the processes by which a living

    organism obtains its energy troughbreaking down larger molecules intosmaller ones.- release energy (exergonic reaction)- E.g : cell respiration

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    Exergonic and Endergonic Reactionsin Metabolism

    An exergonic reaction

    Proceeds with a net release of freeenergy and is spontaneous

    Figure 8.6

    Reactants

    Products

    Energy

    Progress of the reaction

    Amountofenergyreleased(G

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    FOOD(BIG MOLECULES)

    SMALL MOLECULES

    ENERGY

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    Anabolism

    the processes by which energy and rawmaterials are used to buildmacromolecules To build components of cells such asproteins and nucleic acids. needs energy (endergonic reactions).

    E.g: photosynthesis, protein synthesis

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    ENERGY

    BIG

    MOLECULES

    SMALL MOLECULES

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    An endergonic reaction

    Is one that absorbs free energy from itssurroundings and is nonspontaneous

    Figure 8.6

    Energy

    Products

    Amount ofenergyreleased(G>0)

    Reactants

    Progress of the reaction

    Free

    energy

    (b) Endergonic reaction: energy required

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    Factors affecting metabolism

    ATP (Adenosine triphosphate) is thesubstance released energy inmetabolism process.

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    The Structure andHydrolysis of ATP

    ATP (adenosine triphosphate) Is the cells energy shuttle

    Provides energy for cellular functions

    Figure 8.8

    O O O O CH2

    H

    OH OH

    H

    N

    H H

    O

    NC

    HC

    N CC

    N

    NH2Adenine

    RibosePhosphate groups

    O

    O O

    O

    O

    O

    -

    - - -

    CH

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    Energy is released from ATP

    When the terminal phosphate bond is

    broken

    Figure 8.9

    P

    Adenosine triphosphate (ATP)

    H2O

    + Energy

    Inorganic phosphate Adenosine diphosphate (ADP)

    PP

    P PP i

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    The Regeneration of ATPCatabolic pathways

    Drive the regeneration of ATP from ADPand phosphate

    ATP synthesis fromADP + P i requires energy

    ATP

    ADP + P i

    Energy for cellular work(endergonic, energy-consuming processes)

    Energy from catabolism(exergonic, energy yieldingprocesses)

    ATP hydrolysis toADP + P i yields energy

    Figure 8.12

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    Factors affecting metabolism

    SUBSTANCES CHANGED INMETABOLISM PROCESS

    (Such as Glucose in Glycolisis)

    Substrate

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    Factors affecting metabolism

    enzymes

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    The chemical reaction of metabolism

    need enzyme to accelerate a reaction.

    What are enzymes ?

    http://localhost/var/www/apps/conversion/tmp/scratch_1/enzymetale.swfhttp://localhost/var/www/apps/conversion/tmp/scratch_1/enzymetale.swf
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    - Enzymes are proteins (tertiary and

    quaternary structures as catalyst toaccelerate a reaction.

    - Enzymes are specific for what they

    will catalyst.- End in ase (ex:sucrase, lactase,

    maltase)

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    Enzym Characteristic

    Act as catalystto accelerate a reaction Not permanently changed in the process.

    Reusable

    Enzym are unaffected by the reaction thatthey speed up.

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    Enzymes

    FreeEnergy

    Progress of the reactions

    Reactants

    Products

    Free energy of activation

    Without Enzyme

    With Enzyme

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    maltase

    Maltose glucose glucose

    Is anenzyme

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    Substrate

    ENZYMEENZYME-SUBSTRATE

    ENZYME

    Product

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    Evaluation Seluruh reaksi kimia di dalam tubuh organisme disebut .

    Proses pemecahan molekul besar menjadi molekul yang lebih kecildisebut.

    Jika ATP dipecah menjadi ADP dan P akan menghasilkan ..

    Yang mengkatalis reaksi disebut.

    Enzyme is a protein (True or false)

    The processes by which energy and raw materials are used to build

    macromolecules is.. Enzyme will change permanently after being used (True or False)

    Yang menurunkan energi aktivasi dalam suatu reaksi adalah ..

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    Metabolisme

    Katabolisme

    Enzim True

    Anabolism

    False enzim