metabolism powerpoint
TRANSCRIPT
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METABOLISM
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Look at the picture !
What are theydoing?
What must they
have to do that?
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Energy
Energy is the capacity of a
physical system to perform work
Forms of Energy
Is the capacity to cause change
Exists in various forms, of whichsome can perform work
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The First Law ofThermodynamics
According to the first law ofthermodynamics
Energy can be transferred andtransformed
Energy cannot be created ordestroyed
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Where can they get it?
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They getenergy fromfood
How can foodbe changedinto energy?
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Food changed into energy by
one of the metabolismprocess.
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METABOLISM
DIVIDE INTO
FACTORS
ANABOLISM
CATABOLISM
ENZYMES
SUBSTRATE
ATP
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METABOLISM
Metabolism is the
set of chemical
reactions that occur
in living organisms
to maintain life.
Metabolism is usually
divided into two
categories:
1. Catabolism
2. Anabolism
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Catabolism
- is the processes by which a living
organism obtains its energy troughbreaking down larger molecules intosmaller ones.- release energy (exergonic reaction)- E.g : cell respiration
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Exergonic and Endergonic Reactionsin Metabolism
An exergonic reaction
Proceeds with a net release of freeenergy and is spontaneous
Figure 8.6
Reactants
Products
Energy
Progress of the reaction
Amountofenergyreleased(G
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FOOD(BIG MOLECULES)
SMALL MOLECULES
ENERGY
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Anabolism
the processes by which energy and rawmaterials are used to buildmacromolecules To build components of cells such asproteins and nucleic acids. needs energy (endergonic reactions).
E.g: photosynthesis, protein synthesis
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ENERGY
BIG
MOLECULES
SMALL MOLECULES
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An endergonic reaction
Is one that absorbs free energy from itssurroundings and is nonspontaneous
Figure 8.6
Energy
Products
Amount ofenergyreleased(G>0)
Reactants
Progress of the reaction
Free
energy
(b) Endergonic reaction: energy required
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Factors affecting metabolism
ATP (Adenosine triphosphate) is thesubstance released energy inmetabolism process.
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The Structure andHydrolysis of ATP
ATP (adenosine triphosphate) Is the cells energy shuttle
Provides energy for cellular functions
Figure 8.8
O O O O CH2
H
OH OH
H
N
H H
O
NC
HC
N CC
N
NH2Adenine
RibosePhosphate groups
O
O O
O
O
O
-
- - -
CH
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Energy is released from ATP
When the terminal phosphate bond is
broken
Figure 8.9
P
Adenosine triphosphate (ATP)
H2O
+ Energy
Inorganic phosphate Adenosine diphosphate (ADP)
PP
P PP i
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The Regeneration of ATPCatabolic pathways
Drive the regeneration of ATP from ADPand phosphate
ATP synthesis fromADP + P i requires energy
ATP
ADP + P i
Energy for cellular work(endergonic, energy-consuming processes)
Energy from catabolism(exergonic, energy yieldingprocesses)
ATP hydrolysis toADP + P i yields energy
Figure 8.12
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Factors affecting metabolism
SUBSTANCES CHANGED INMETABOLISM PROCESS
(Such as Glucose in Glycolisis)
Substrate
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Factors affecting metabolism
enzymes
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The chemical reaction of metabolism
need enzyme to accelerate a reaction.
What are enzymes ?
http://localhost/var/www/apps/conversion/tmp/scratch_1/enzymetale.swfhttp://localhost/var/www/apps/conversion/tmp/scratch_1/enzymetale.swf -
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- Enzymes are proteins (tertiary and
quaternary structures as catalyst toaccelerate a reaction.
- Enzymes are specific for what they
will catalyst.- End in ase (ex:sucrase, lactase,
maltase)
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Enzym Characteristic
Act as catalystto accelerate a reaction Not permanently changed in the process.
Reusable
Enzym are unaffected by the reaction thatthey speed up.
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Enzymes
FreeEnergy
Progress of the reactions
Reactants
Products
Free energy of activation
Without Enzyme
With Enzyme
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maltase
Maltose glucose glucose
Is anenzyme
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Substrate
ENZYMEENZYME-SUBSTRATE
ENZYME
Product
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Evaluation Seluruh reaksi kimia di dalam tubuh organisme disebut .
Proses pemecahan molekul besar menjadi molekul yang lebih kecildisebut.
Jika ATP dipecah menjadi ADP dan P akan menghasilkan ..
Yang mengkatalis reaksi disebut.
Enzyme is a protein (True or false)
The processes by which energy and raw materials are used to build
macromolecules is.. Enzyme will change permanently after being used (True or False)
Yang menurunkan energi aktivasi dalam suatu reaksi adalah ..
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Metabolisme
Katabolisme
Enzim True
Anabolism
False enzim