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Meningitis vaccines
Dr Brenda CorcoranNational Immunisation Office
World Meningitis Day24 April 2018www.immunisation.ie
: Dates vaccines introduced into the Irish immunisation schedule
Vaccine Date introduced
Hib 1992MenC (catch up 2000-2002) 2000Hib booster (catch up 2005) 2006PCV7 (catch up 2008-10) 2008PCV13 2010MenC (adolescent booster) 2014MenB 2016
• Non live vaccines• Can be given on same day or at any interval from other vaccines
Hib vaccine
• Part of 6in1 vaccine (Infanrix hexa) – 2, 4 and 6 months – Must be reconstituted
• Booster (Menitorix)– Hib/MenC combined at 13 months
• Late entrant – 1 dose up to 10 years of age
www.immunisation.ie
www.immunisation.ie
MenC vaccine• MenC (Menjugate) at 6 months• Hib/MenC combined vaccine at 13 months
• Concerns about waning immunity in adolescents– MenC booster introduced for 1st years in 2014/15– No catch up programme
• Late entrant – 1 dose up to 23 years
• MenACWY vaccine recommended in UK since 2015/2016 (including catch up for college students)– Under review by NIAC – no change to date
www.immunisation.ie
PCV vaccine
• PCV13 (Prevenar13) at 2 and 6 months• Booster PCV13 (Prevenar13) at 13 months
• Late entrant – 1 dose up to 2 years
www.immunisation.ie
MenB vaccine• MenB (Bexsero) at 2 and 4 months• Booster MenB (Bexsero) at 13 months
• Late entrant (born on or after 1/10/16)
• Prophylactic paracetamol required up to 12 months when given with other PCI vaccines
Age No. of doses Timing
3 to <10 months 3 2 doses 2 months apart,
3rd dose at >12 months at least 2 months after dose 2
10 months and older 2 2 doses 2 months apart
Vaccine uptake rate at 24 months1999-2017
Target 95%
www.immunisation.ie
95% Hib3 92% PCVb90% Hibb 88% MenCb
Source: HPSC
MenCb uptake at 24 months Q4 2017
www.immunisation.ieSource: HPSC
Vaccine uptake at 12 months 2000- 2017
www.immunisation.ie
91% MenB2 89% Hib388% MenC1 88% PCV2
Source: HPSC
Target 95%
MenC1 uptake at 12 months Q4 2017
www.immunisation.ieSource: HPSC
MenC booster uptake 2014/15 – 2016/17
www.immunisation.ie
Medically at risk
For more details see new Chapters of the Immunisation Guidelines (to be published shortly)https://www.hse.ie/eng/health/immunisation/hcpinfo/guidelines/immunisationguidelines.html
www.immunisation.ie
MenACWY MenB PCV Hib
Asplenia and hyposplenism √ √ √ √HIV infection √ √ √ XImmunomodulatory treatment √ √ X XHaematopoietic stem cell transplant √ √ √ √Solid organ transplant √ √ √ X
Vaccine supplies
• All vaccines available from the National Cold Chain Service(except for private/travel use)
• Single Hib vaccine (Hiberix) no longer available => use Hib/MenC (Menitorix) instead
• Any issues contact [email protected]
www.immunisation.ie
www.immunisation.ie
23-29 April 2018
@HSEimm#vaccineswork#immunizeEurope