mendel’s legacy 9.1. background on gregor mendel: austrian monk austrian monk studied science...
TRANSCRIPT
![Page 1: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/1.jpg)
Mendel’s LegacyMendel’s Legacy
9.19.1
![Page 2: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/2.jpg)
Background on Background on Gregor Gregor Mendel:Mendel:
Austrian monk Austrian monk Studied science & Studied science &
math at the University math at the University of Vienna of Vienna
Formulated Formulated thethe Laws Laws of Heredityof Heredity in the in the early 1860's early 1860's
Did a statistical study of traits in garden peas over an eight year period
![Page 3: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/3.jpg)
33
Mendel stated that Mendel stated that physical traits are physical traits are inherited as inherited as “particles”“particles”Mendel did not Mendel did not know that the know that the “particles” were “particles” were actually actually Chromosomes & Chromosomes & DNADNA
Particulate InheritanceParticulate Inheritance
![Page 4: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/4.jpg)
GeneticsGenetics - - study of study of heredity heredity
TraitsTraits – any characteristic that can – any characteristic that can be passed from parent to offspring be passed from parent to offspring E.g. height, eye colorE.g. height, eye color
HeredityHeredity – passing of traits from – passing of traits from parent to offspringparent to offspring
![Page 5: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/5.jpg)
PollinationPollination – when pollen grains which – when pollen grains which contain sperm are produced in the male contain sperm are produced in the male reproductive parts reproductive parts antheranther of a flower of a flower are transferred to the female are transferred to the female reproductive part reproductive part stigma stigma which holds which holds the ovary where the eggs arethe ovary where the eggs are
Ovary
![Page 6: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/6.jpg)
Self-pollinationSelf-pollination – pollination of – pollination of same flower or flower on same plantsame flower or flower on same plant
Cross-pollinationCross-pollination – involves 2 – involves 2 separate plantsseparate plants
Types of pollination:Types of pollination:
![Page 7: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/7.jpg)
Mendel’s experimentsMendel’s experiments
PurePure plants always produce offspring plants always produce offspring with that traitwith that trait
A A strainstrain refers to plants that are pure refers to plants that are pure for a specific trait e.g. all having for a specific trait e.g. all having yellow floweryellow flower
PP1 1 generationgeneration – each parental strain – each parental strain
![Page 8: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/8.jpg)
Terms to knowTerms to know GenotypeGenotype - gene combination for a trait - gene combination for a trait
(e.g. RR, Rr, rr) (e.g. RR, Rr, rr) PhenotypePhenotype - the physical feature - the physical feature
resulting from a genotype (e.g. tall, short)resulting from a genotype (e.g. tall, short) The trait that is expressed or The trait that is expressed or showsshows) )
GeneGene – segment of DNA on a – segment of DNA on a chromosome that controls a particular chromosome that controls a particular hereditary traithereditary trait
AlleleAllele – each alternative form of a gene – each alternative form of a gene (paired)(paired)
![Page 9: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/9.jpg)
AllelesAlleles – are two forms of a gene – are two forms of a gene (dominant & recessive) (dominant & recessive)
DominantDominant - stronger of two genes - stronger of two genes expressed in the hybrid; represented expressed in the hybrid; represented by a capital letter (R) by a capital letter (R)
RecessiveRecessive - gene that shows up less - gene that shows up less often in a cross; represented by a often in a cross; represented by a lowercase letter (r) lowercase letter (r)
More termsMore terms
![Page 10: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/10.jpg)
Mendel cross-pollinated two strains and tracked Mendel cross-pollinated two strains and tracked each trait through two generations (e.g. TT x tt ) each trait through two generations (e.g. TT x tt )
The offspring of this cross were all The offspring of this cross were all hybridshybrids showing only the dominant trait & were called showing only the dominant trait & were called
the the First Filial or F1 generationFirst Filial or F1 generation
Trait - plant heightTrait - plant height
Alleles - T tall, t shortAlleles - T tall, t short
PP11 cross TT x tt cross TT x tt genotype -- Ttgenotype -- Tt
tt tt phenotype -- Tallphenotype -- Tall
TT TtTt TtTt genotypic ratio --all genotypic ratio --all
alikealike
TT TtTt TtTt
phenotypic ratio- all phenotypic ratio- all
alikealike
![Page 11: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/11.jpg)
He cross-pollinated He cross-pollinated
FF11 generation generation – (first filial) offspring of P1 – (first filial) offspring of P1 Hybrid Hybrid - only showing the dominant trait - only showing the dominant trait (filial means having or assuming the relation of (filial means having or assuming the relation of
a child or offspring)a child or offspring)
Plants allowed to cross-pollinate produced Plants allowed to cross-pollinate produced FF22 generation generation – offspring of F – offspring of F11
![Page 12: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/12.jpg)
Mendel then crossed two of his F1 plants Mendel then crossed two of his F1 plants and tracked their traits; known as an F1 and tracked their traits; known as an F1
crosscross Trait - plant heightTrait - plant height
Alleles - T tall, t shortAlleles - T tall, t short
FF11 cross Tt x Tt cross Tt x Tt genotype -- TT, genotype -- TT, Tt, ttTt, tt
TT tt phenotype -- Tall phenotype -- Tall
& short& short
TT TTTT TtTt genotypic ratio --genotypic ratio --
1:2:11:2:1
tt TtTt tttt phenotypic ratio- 3:1phenotypic ratio- 3:1
![Page 13: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/13.jpg)
When 2 hybrids were crossed, 75% When 2 hybrids were crossed, 75% (3/4) of the offspring showed the (3/4) of the offspring showed the dominant trait & 25% (1/4) showed dominant trait & 25% (1/4) showed the recessive trait; the recessive trait; always a 3:1 always a 3:1 ratioratio
The offspring of this cross were The offspring of this cross were called the F2 generation called the F2 generation
![Page 14: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/14.jpg)
50% (1/2) of the offspring in a test cross showed the 50% (1/2) of the offspring in a test cross showed the same genotype of one parent & the other 50% same genotype of one parent & the other 50%
showed the genotype of the other parent; always a showed the genotype of the other parent; always a
1:1 ratio1:1 ratio TraitTrait - Plant Height - Plant Height
AllelesAlleles - T tall, t short - T tall, t short
FF22 cross TT x Tt cross TT x Tt FF22 cross tt x Tt cross tt x Tt
TT tt TT tt
TT TTTT TtTt tt TtTt tttt
TT TTTT TtTt tt TtTt tttt
genotype - TT, Ttgenotype - TT, Tt genotype - tt, Ttgenotype - tt, Tt
phenotype - Tallphenotype - Tall
phenotype - Tall & phenotype - Tall & shortshort
genotypic ratiogenotypic ratio - 1:1- 1:1 genotypic ratiogenotypic ratio - 1:1- 1:1
phenotypic ratiophenotypic ratio – all – all alikealike
phenotypic ratiophenotypic ratio - 1:1- 1:1
![Page 15: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/15.jpg)
•Mendel then crossed a pure & a hybrid from his F2 generation; known as an F2 or test cross
•Why???
![Page 16: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/16.jpg)
1616
Test CrossTest CrossA mating between an individual of A mating between an individual of unknown genotype unknown genotype
and a and a homozygous recessivehomozygous recessive (bb) individual will give (bb) individual will give info on the unknown genotype.info on the unknown genotype.
Example:Example: bbC__ bbC__ x x bbccbbcc
BB = brown eyesBB = brown eyesBb = brown eyesBb = brown eyesbb = blue eyesbb = blue eyes
CC = curly hairCC = curly hairCc = curly hairCc = curly haircc = straight haircc = straight hair
bCbC b___b___
bcbc
![Page 17: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/17.jpg)
Problems:Problems: Work the P1, F1, and both F2 Work the P1, F1, and both F2 crosses for all of the other pea plant traits & be crosses for all of the other pea plant traits & be
sure to include genotypes, phenotypes, sure to include genotypes, phenotypes,
genotypic & phenotypic ratiosgenotypic & phenotypic ratios Mendel's traits included:Mendel's traits included: a. a. Seed shapeSeed shape --- Round (R) or Wrinkled --- Round (R) or Wrinkled
(r)(r) b. b. Seed ColorSeed Color ---- Yellow (Y) or Green (y) ---- Yellow (Y) or Green (y) c. c. Pod ShapePod Shape --- Smooth (S) or wrinkled (s) --- Smooth (S) or wrinkled (s) d. d. Pod ColorPod Color --- Green (G) or Yellow (g) --- Green (G) or Yellow (g) e. e. Seed Coat ColorSeed Coat Color --- Gray (G) or White --- Gray (G) or White (g)(g) f. f. Flower positionFlower position --- Axial (A) or Terminal --- Axial (A) or Terminal (a)(a) g. g. Plant HeightPlant Height --- Tall (T) or Short (t) --- Tall (T) or Short (t) h. h. Flower color --- Flower color --- Purple (P) or white (p)Purple (P) or white (p)
![Page 18: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/18.jpg)
1818
![Page 19: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/19.jpg)
1919
![Page 20: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/20.jpg)
Law of SegregationLaw of Segregation - - states that each genetic trait is produced states that each genetic trait is produced
by a pair of alleles which separate by a pair of alleles which separate (segregate) during reproduction(segregate) during reproduction
RrRr
RR rr
![Page 21: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/21.jpg)
2121
Law of SegregationLaw of Segregation
During the During the formation of gametes formation of gametes (eggs or sperm), the (eggs or sperm), the two alleles two alleles responsible for a trait responsible for a trait separate separate from each other.from each other.
Alleles for a trait are then Alleles for a trait are then ”recombined" at fertilization”recombined" at fertilization, , producing the genotype for the producing the genotype for the traits of the offspringtraits of the offspring..
![Page 22: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/22.jpg)
Law of Independent Law of Independent AssortmentAssortment
states that each factor (gene) is states that each factor (gene) is distributed (assorted) distributed (assorted) randomlyrandomly and and independently of one another in the independently of one another in the formation of gametes during meiosis formation of gametes during meiosis
R r Y yR r Y y
RYRY RyRy rYrY ryry
![Page 23: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/23.jpg)
Molecular geneticsMolecular genetics - -
The study of the structure and The study of the structure and function of chromosomes and genesfunction of chromosomes and genes
![Page 24: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/24.jpg)
Mendel also crossed Mendel also crossed plants thatplants that
differed in two characteristics differed in two characteristics ((DiDihybrid Crosses)hybrid Crosses)e.g. seed shape & seed color e.g. seed shape & seed color
![Page 25: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/25.jpg)
In the P1 cross, RRYY x rryy, all of the In the P1 cross, RRYY x rryy, all of the F1 offspring showed only the dominant F1 offspring showed only the dominant form for both traits; all form for both traits; all hybridshybrids, RrYy, RrYy
Traits: Seed Shape & Seed ColorTraits: Seed Shape & Seed Color
Alleles: R round Y yellowAlleles: R round Y yellow r wrinkled y green r wrinkled y green
PP11 Cross: Cross: RRYY x RRYY x r r yy r r yy
ryry
Genotype:Genotype: RrYyRrYy
RYRYRrYyRrYy
Phenotype:Phenotype: Round yellow Round yellow
seedseed
Genotypic Genotypic ratio:ratio: All alikeAll alike
Phenotypic Phenotypic
ratio:ratio: All AlikeAll Alike
![Page 26: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/26.jpg)
Homozygous genotypeHomozygous genotype - gene - gene combination involving 2 dominant or 2 combination involving 2 dominant or 2 recessive genes (e.g. RR or rr); also called recessive genes (e.g. RR or rr); also called purepure (homo=same,alike,man)(homo=same,alike,man)
Heterozygous genotypeHeterozygous genotype - gene - gene combination of one dominant & one combination of one dominant & one recessive allele (e.g. Rr); also called recessive allele (e.g. Rr); also called hybridhybrid
(hetero=different, other, opposite)(hetero=different, other, opposite)
combinationscombinations
![Page 27: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/27.jpg)
When Mendel crossed 2 hybrid plants When Mendel crossed 2 hybrid plants
(F1 cross), he got the following results:(F1 cross), he got the following results:
RYRY RyRy rYrY ryry
RYRY RRRRYYYY
RRRRYyYy
RrYRrYYY
RrYRrYyy
RyRy RRRRYyYy
RRRRyyyy
RrYRrYyy
RryRryyy
rYrY RrYRrYYY
RrYRrYyy
rrYrrYYY
rrYrrYyy
ryry RrYRrYyy
RryRryyy
rrYrrYyy
rryrryyy
Traits: Seed Shape & Traits: Seed Shape & Seed ColorSeed Color
Alleles: Alleles: R - round Y- R - round Y-
yellow yellow r - wrinkled y greenr - wrinkled y green
![Page 28: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/28.jpg)
GenotypesGenotypes Genotypic Genotypic ratioratio
PenotypePenotype Phenotypic Phenotypic ratioratio
RRYYRRYY
RRYyRRYy
RrYYRrYY
RrYyRrYy
11
22
22
44
Round yellow Round yellow seedseed
99
RRyyRRyy
RryyRryy11
22Round green Round green seedseed
33
rrYYrrYY
rrYyrrYy11
22Wrinkled Wrinkled yellow seedyellow seed
33
rryyrryy 11 Wrinkled green Wrinkled green seedseed
11
![Page 29: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/29.jpg)
Problem:Problem:
Choose two other pea plant traits Choose two other pea plant traits and work the P1 and F1 dihybrid and work the P1 and F1 dihybrid crosses. Be sure to show the trait, crosses. Be sure to show the trait, alleles, genotypes, phenotypes, and alleles, genotypes, phenotypes, and all ratios.all ratios.
![Page 30: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/30.jpg)
tutorialtutorial
http://w3.dwm.ks.edu.tw/bio/activelearner/10/ch10intro.html
![Page 31: Mendel’s Legacy 9.1. Background on Gregor Mendel: Austrian monk Austrian monk Studied science & math at the University of Vienna Studied science & math](https://reader030.vdocuments.site/reader030/viewer/2022032722/56649cf65503460f949c5768/html5/thumbnails/31.jpg)
ReferencesReferences
http://sps.k12.ar.us/massengale/mendelian_genetics.htm