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GANPAT UNIVERSITY

MEHSANA URBAN INSTITUTE OF SCIENCES www.ganpatuniversity.ac.in , www.mubiob.ac.in

◄SYLLABUS►

M.Sc. ORGANIC CHEMISTRY

(Effective from July, 2013-14)

SEMESTER NO. SUBJECT PAGE NO.

SEMESTER- I

Inorganic Chemistry 2

Organic Chemistry 3

Physical Chemistry - I 4

Basic Instrumental Methods of Analysis 5

Language and Communication Skills 6

Practical Course – I 7

SEMESTER-II

Modern Analytical Techniques 8

Industrial Organic Chemistry 9

Physical Chemistry - II 10

Statistics and Computer Applications 11

Entrepreneurship Development 12

Practical Course – II 13

SEMESTER-III

Organic Synthesis and Reaction Mechanism 14

Organic and Computational Chemistry 15

Medicinal Chemistry 16

Research Methodology 17

Practical Course – III 18

SEMESTER- IV Project Work 19

LIBRARY COPY

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Syllabus- MUIS

Mehsana Urban Institute of Sciences, Ganpat University Page No.1

Semester-I:

No Code Type Name of Subject Hrs/week

(Theory) Credit

Hrs/week

(Practical) Credit

1 CHE 101 ICH Core Inorganic Chemistry 03 03 - -

2 CHE 102 OCH Core Organic Chemistry 03 03 - -

3 CHE 103 PCH Core Physical Chemistry - I 03 03 - -

4 CHE 104 BMA Complementary Basic Instrumental Methods

of Analysis 02 02 - -

5 CHE 105 LCS Common Language and

Communication Skills 02 02

6 CHE 106 PRA Core Practical Course - I - - 12 06

Total 13 13 12 06

Semester-II:

No. Code Type Name of Subject Hrs/week

(Theory) Credit

Hrs/week

(Practical) Credit

1 CHE 201 MAT Core Modern Analytical

Techniques 03 03 - -

2 CHE 202 IOC Core Industrial Organic Chemistry 03 03 - -

3 CHE 203 PCH Core Physical Chemistry - II 03 03 - -

4 CHE 204 SCA Complementary Statistics and Computer

Applications 02 02 - -

5 CHE 205 EDM Common Entrepreneurship

Development 02 02

6 CHE 206 PRA Core Practical Course - II - - 12 06

Total 13 13 12 06

Semester-III:


(Theory) Credit

Hrs/week

(Practical) Credit

1 CHE 301 OSR Core Organic Synthesis and

Reaction Mechanism 03 03 - -

2 CHE 302 OCC Core Organic and Computational

Chemistry 03 03 - -

3 CHE 303 MCH Core Medicinal Chemistry 03 03 - -

4 CHE 304 RMD Complementary Research Methodology 03 03 - -

5 CHE 305 PRA Core Practical Course - III - - 12 06

Total 12 12 12 06

Semester-IV:


(Theory) Credit

Hrs/week

(Practical) Credit

1 CHE 401 PRO Core Project 18 18 - -

Total 18 18 - -

Syllabus- MUIS


SEMESTER-I

CHE 101 ICH: INORGANIC CHEMISTRY

Unit Content Hrs.

1 Valency

Variation method, Seculas equation, Stability of H+ ion MO approach, Stability of H2 molecule- V.B.

approach, Classical interaction energy, Representation of wave function for SP, SP2 & SP

3 hybrid

orbitals, bond angel and bond strength, M.O. treatment of Octahedral complexes, Quantum mechanical

representation of Pauli Exclusion principle

8

2 & 3 Matter waves: Wave particle duality of material, Theory of wave motion, Particle wave Schrodinger

equation for particle wave.

Quantum Mechanical Formalism: Operators, Eigen values, Eigen functions, Basic postulates of

quantum mechanics, some typical theorems relating to basic postulate.

Translation Motion of Particle: Free particle system, Particle in a box, Particle with finite potential

barrier, Potential barrier of definite thickness.

15

4 Co-ordination compound

Stability of co-ordination compound: Introduction, Thermodynamic stability, Kinetic stability, Instability

constant, Stability constant, Factors affecting the stability of complex ions, Methods for determination of

stability constant and composition of complex

7

5 & 6 Symmetry

Symmetry elements & SY operation, Multiplication of SY operations, Multiplication table for C2v, C3v &

C2h point group only, Classification of schoonflies point group, Determination of schoonflies point group

notation

Representation of Group

Some properties of Matrices & Vectors, Representation of Group, The Great orthogonality theorem and

its consequences, Character tables, Reducible & irreducible representation

Application part

Study of molecular vibration, Study of Γ3N, Separation of Irreducible representation from ΓVib, To

determine IR & Raman activity, Hybridization of orbitals (only 6 hybrid orbitals), AB3 Trigonal plannes,

AB4 Tetrahedral, AB4 Square plannes, AB5 Trigonal by pyramidal, AB5 Square pyramidal, AB6

Octahedral, AB2

15

Reference Books:

1. Concise Inorganic chemistry by J D Lee

2. Valence and molecular structure by Castmall and Flower

3. Quantum chemistry by R K Prasad

4. Co-ordination chemistry by Gurdeep Chatwal, M S Yadav

5. Chemical application of Gtroup theory by F A Cotton

6. Chemical Bonding by Raval Patel & Patel

7. Group theory & its application by P K Bhattacharya

Syllabus- MUIS


CHE 102 OCH: ORGANIC CHEMISTRY

Unit Content Hrs.

1

Basic introduction to organic chemistry

Concept of aromaticity: delocalization of electrons – Hückel’s rule, criteria for aromaticity,

examples of neutral and charged aromatic systems – annulenes. NMR as a tool for aromaticity.

Anti-and homo-aromatic systems.

Aliphatic nucleophilic substitution, SN2 reaction, SN1 Mechanism-Ion Pairs and other aspects, Sni

and SET mechanisms, Neighboring group participation.

Elimination reactions: E1, E2 and E1cB mechanism, elimination versus substitution.

8

2 Functional Group analysis

a). Hydroxyl group like alcohols, Glycols, Phenols by esertification procedure with various

reagents.

b). Carbonyl group by Oxime, Bisulphite, Hydrazone, Oxidation, Schiff’s base methods.

c). Carboxylic acids and its derivatives (salt, esters, amides, chlorides anhydrides) by titrimetric,

Combustion, Saponification, Potentiometric, and Reduction methods.

d). Amino group by titration, Acylation, Drazotization, Bromination methods.

e). Unsaturation by Bromination, Iodine number, Hydrogenation, Ozonization, epoxidation

methods.

7

3 Stereochemistry of Organic Compounds

Stereoisomerism: definition based on symmetry and energy criteria, configuration and

conformational stereoisomers. Conformational analysis of acyclic systems.

Cyclostereoisomerism: Configuration, conformation and stability of cyclohexanes,

Cyclohexanones, Halocyclohexanones, Cyclic directionality of constitutional origin.

Stereoselective reactions and stereospecific reactions

8

4 Topicity and prostereoisomerism

Topicity and prostereoisomerism: Introduction, topicity of ligands and faces as well as their

nomenclature. NMR distinction of enantiotopic/diastereotopic ligands.

7

5 Heterocyclic Chemistry

a). Introduction-nomenclature involved in five membered and six membered heterocycles with one,

two or more heteroatoms.

b). Biological importance of Heterocycles.

c). Three- membered and four- membered heterocycles- synthesis and reactions of aziridines,

oxiranes, thiranes, azetidines, and oxetanes.

d). Five and Six Membered- Imidazol, Pyrazole, Thiazole, Pyridine, Pyrimidine.

8

6 Reactions of carboxylic acids and esters

BAC2, AAC2, BAL2, BAL1, AAL1. Claisen condensation, decarboxylation, cabanions, enols,

keto-enol equilibrium, Transesterification and ester interchange, steric hindrance in esterification

and hydrolysis.

7

Reference Books:

1. A. R. Katrizky and C. W. Rees: Comprehensive Heterocyclic Chemistry, Pergamon.

2. R. M. Acheson : An Introduction to Chemistry of Heterocyclic Compounds (Interscience)

3. J. March., Adv. Organic Chemistry: Reactions, Mechanisms and Structure, John Wiley

4. P. S. Kalsi. Stereochemistry, Conformation and Mechanism, New Age International

5. Peter Sykes, A guide book to mechanism in Organic chemistry, Orient-Longmans

6. E. L. Eliel, S.H. Wilen, Stereochemistry of Organic Compounds, John Wiley & Sons.

7. D. Nasipuri, Stereochemistry of Organic Compounds: Principles and Applications, 3rd

Ed, New Age Publis.

8. Quantitative organic analysis via functional group by S. Siggia and J.C. Hanna.

Syllabus- MUIS


CHE 103 PCH: PHYSICAL CHEMISTRY - I

Unit Content Hrs

1 Adsorption: Surface tension, Curved surfaces, The Lapace-young equation, Pressure across a spherical

surface, Capillary action, Laplace equation, Vapour pressure of droplets-Kelvin equation, Adsorption,

Adsorbate, Adsorbent, Absorption, Sorption, Occlusion, Measurement of Adsorption, Factors affecting

adsorption, Types of adsorption, Adsorption isotherms, The freundlich adsorption isotherm, The

Langmuir adsorption isotherm, The BET theory of multilayer adsorption, Derivation of BET equation,

The Gibbs adsorption isotherm, Numerical

8

2 Thermodynamics: Nernst’s heat theorm, Third law of thermodynamics, Comparison of Nernst’s

theorm with third law, Application of third law of thermodynamics, Partial molar properties, Concept of

chemical potential, Gibbs-Duhem equation, Gibbs-Duhem-margules equation, Determination of partial

molar quantities, Chemical potential of a system of ideal gases, Non-ideal solution, Thermodynamic

functions of mixing of non-ideal solution, Numerical

8

3 Activity and Fugacity: Determining activity and activity coefficient, Variation of activity of a gas with

pressure and temperature, Variation of activity with temperature and pressure in liquid mixture, Concept

of fugacity, Determination of fugacity, Variation of fugacity with temperature and pressure, Fugacity of

solids and liquids, Fugacity of gas in mixture of real gases, Determination of fugacity of gas in a

mixture, Numerical

7

4 Liquid Crystals (The mesomorphic state): Liquid crystals, Vapour pressure-temperature diagrams,

Thermography, LCDS and the seven segment cell, Classification of thermotropic liquid crystals,

Smectic liquid crystals, Nematic liquid crystals, Cholesteric liquid crystals, Disc shaped liquid crystals,

Polymer liquid crystals, Polymorphism in thermotropic liquid crystals, Pressure-induced

mesomorphism, Molecular arrangements in various states of liquid crystals, The glass state, Numerical

7

5 Chemical Kinetics : Introduction of chemical kinetics, Rate od reaction, Rate law and rate constant,

Order of reaction, Integration of rate expressions, Second order reactions (a=b) and (a≠b), Third order

reaction (a=b=c), (a=b≠c) and (a≠b≠c), Nth

order reaction, Half-life time of a reactions, 1st, 2

nd, 3

rd and

Nth

order reactions, Kinetics of complex reactions, Opposing reactions, Consecutive reactions, Chain

reactions, Branched chain reactions, Numerical

8

6 Theories of unimolecular gaseous reactions: Hinshelwood theory, Lindemann theory, RK theory,

RRKM theory, Effect of temperature on reaction rates, Arrhenium equation, Activation energy, Kinetic

salt effect (primary and secondary), Kinetic of thermal H2 + Br2 reactions, Kinetic of decomposition of

ethane, Kinetic of photochemical H2 + Cl2 reactions, Numerical

7

Reference Books:

1. Textbook of physical chemistry – W.J.Moore

2. Textbook of physical chemistry – Glasstone

3. Textbook of physical chemistry – P.Atkins

4. Advanced physical chemistry – Surdeep Raj

5. Advanced physical chemistry – J.N.Gurtu, A.Gurtu

6. Thermodynamics for chemists –Glasstone

7. Physical chemistry – S. Castellian

8. Thermodynamics of non equilibrium processes- Karapitianeh

9. Chemical Kinetics- Laidler

10. Chemical Kinetics – Frost and Pearson

11. Solid state chemistry – H.Keer

12. Solid state chemistry- Hannay

13. Chemistry of solids – Azaroff

14. Surface chemistry – Adamson

15. Surface chemistry – Osipov

Syllabus- MUIS


CHE 104 BMA: BASIC INSTRUMENTAL METHODS OF ANALYSIS

Unit Content Hrs.

1 Basics of instrumental analytical methods: Advantages and limitations.

Solvent extraction- Efficiency of extraction, Selectivity of extraction, Extraction system, Method of

Extraction, applications.

Basic introduction to chromatographic techniques: Introduction, Principles and Theory,

classification of chromatographic techniques, paper chromatography, Thin Layer chromatographic,

Column chromatography.

8

2 Potentio and pH metric methods: Standard reduction potentials, various electrodes, electrodes and

cell potential, applications of potentiometry and pH metry, Non-aqueous methods 7

3 Conductometry: Conductance, factors affecting conductance, Kohlrausch law, conductivity cells,

applications.

Polarimetry: Polarimeter, qualitative and quantitative applications

8

4 Polarography, amperometry, biamperometry: Basics of current flow in polarography, dropping

mercury electrode, diffusion current, half wave potential, modifications like pulsed and differential

pulse polarography, stripping voltametry, biamperometric titrations, amperometric titrations

7

Reference Books:

1. Practical Pharmaceutical Chemistry, Vol. I & II by Backett, A. H., 1st ed., CBS Publishers & Distributors,

New Delhi,1997.

2. Pharmaceutical Analysis Part I & II by J. W. Munson, International Medical Book Dist., Mumbai, 2001

3. Fundamentals of Analytical Chemistry by Skoog, Douglas A., 8th ed., Harcourt College Publishers, 2004

4. Quantitative chemical analysis by Mendham,J. 6th ed., Pearson Education, New Delhi, 2009

5. Text Book of Pharmaceutical Analysis by K. A. Connor, 3rd ed., John Willey & Sons, Delhi, 2009.

6. Instrumental method of analysis by Willard Hobartb H., 7th ed., CBS Publishers & Distributors, New

Delhi, 1986.

7. Pharmacopoeia: USP, B.P., I.P.

Syllabus- MUIS


CHE 105 LCS : LANGUAGE AND COMMUNICATION SKILLS

Unit Content Hrs.

1 Language Components: Practical Grammar, Fundamentals of Grammar and Usages, How to

Improve the Command over Spoken and Written English with stress on Noun and Verb, Tenses,

Adjective, Sentence Errors, Punctuation Marks. Common Errors in English.

8

2 Vocabulary Building: synonyms and antonyms, word roots, one-word substitutes, prefixes and

suffixes, study of word origin, analogy, idioms and phrases to encourage the individual to

communicate effectively and diplomatically.

7

3 Introduction to Communication Skills: Basic Forms of Communication, Process of

Communication, Principles of Effective Business Communication, 7 Cs. of Effective Business

Communication, Media of Communication, Barriers of Communication

Group Discussion: dynamics of group discussion, intervention, summarizing, modulation of voice,

body language, relevance, fluency and coherence.

7

4 Reading comprehension: reading for facts, guessing meanings from context, scanning,

skimming, inferring meaning, critical reading. Reading at various speeds (slow, fast, very

fast); reading different kinds of texts for different purposes; reading between the lines

Oral Communication: Principles of Effective Oral Communication, Media of Oral Communication.

8

Reference Books:

1. Wren & Martin; English grammar and composition, 2003.

2. Hand Book of Practical Comunication Skills-Chrissie Wrought,published by Jaico Publishing House.

3. Ray, Reuben; Communication today – Understanding Creative Skills, Himalaya Publishing House, 2001.

4. Effective Technical Communication, M. Ashraf Rizvi, Tata Mc. Graw-Hill Publishing Company Ltd.

5. A course in English communication by Madhavi Apte, Prentice-Hall of India, 2007.

6. Communication Skills by Leena Sen, Prentice-Hall of India, 2005.

7. Kaul, Asha; Business Communication, 1998, Prentice-Hall of India Ltd, New Delhi

8. Raman, Meenakshi & Sharma Sangeeta, Technical Communication, 2006, OUP, New Delhi

Syllabus- MUIS


CHE 106 PRA: PRACTICAL COURSE – I

INORGANIC CHEMISTRY

1 Preparations ( Minimum 5)

Preparation of selected inorganic compounds and their studies by I.R., electronic spectra, Mossbaure, E.S.R. and

magnetic susceptibility measurements. Handling of air and moistuer sensitive compounds.

(1) cis-K[Cr(C2O4)2(H2O)2], (2) Na[Cr(NH3)2(SCN)4], (3) Mn(acac)3, (4) K3[Fe(C2O4)3]

(5) [Co(NH3)6][Co(NO2)6], (6) Hg[Co(SCN)4], (7) [Ni(NH3)6]Cl2

2 Qualitative Analysis (A mixture containing total six radicals) (Minimum 4)

(a) Less common metal ions – TI, Mo, W, Ti, Zr, Th, V, U (one metal ion in cationic/ anionic form)

(b) Insoluble – oxides, sulphates and halides

3 Separation of cations and anions- Paper Chromatography

ORGANIC CHEMISTRY

1 Techniques: Crystallization, distillation, vacuum distillation, steam distillation, thin layer chromatography,

Molecular weight determination by rast camphor method.

2 Estimation of functional groups: Estimation of Hydroxyl group, Carboxylic acid group, Carbonyl group, Ester,

Amines, Amide group and Estimation of Unsaturation.

3 Esterification: Using concentrated sulphuric acid method- Ethyl benzoate, methyl salicylate, n-butly acetate etc.

Using hydrogen chloride method- Ethylp-aminobenzoate, butyl acetae etc. Esterification using others techniques.

4 Preparation of derivatives. Oxime, phenyhydrazine, acetyl, benzoyl, semicarbazide and aryloxyacetic acid,

Anilide, Amide etc.

5 Preparations: Single Stage. a) Benzaldehyde to dibenzylidene acetone, b) Benzaldehyde to cinnamic acid, c)

Benzene to β – benzoyl propionic acid, d) Synthesis using reactions- Friedel Craft reactions, Nitration,

bromination, acylation etc.

6 Experiment based on stereomodels.

PHYSICAL CHEMISTRY SECTION-I

1 Determine the effect on velocity constant of hydrolysis of an ester/ionic reactions

2 Change of concentration of catalyst (HCl)

3 Change of concentration of reactant (Ester)

4 Change of temperature

5 Effect of ionic strength

6 Reaction in micellar media

PHYSICAL CHEMISTRY SECTION-II

1 Determine the strength of halides (KCl + KBr/ KCl + KI) in given mixture by potentiometric titration using 0.1N

AgNO3

2 To determine the solubility of AgCl, Agbr, AgS, Ag2CrO4 using potentiometer

3 Determine the degree of dissociation and dissociation constant in water for the acetic acid conductometrically

4 Determine the amount of HCl and H2C2O4 in given solution by conductometric titration against 0.1N NaOH

5 Determination of Iron in given ore/alloy by solvent extraction

6 Test for adulteration in the given food sample

(a) Ghee (b) Honey (c) Chilly powder (d) Turmeric

7 Determination of Rf value of disperse dye, separation by TLC

8 Determine the concentration of the phosphate in the given softdrink solution by colourimetric method

Reference Books:

1. Quantitative analysis by Arther I.Vogel

2. Quantitative analysis by V.K.Ahluwalia

3. Quantitative analysis by Mann and sanders

Syllabus- MUIS


SEMESTER-2

CHE 201 MAT: MODERN ANALYTICAL TECHNIQUES

Unit Content Hrs.

1 UV – Visible spectroscopy: Theory; Beer and Lambert’s law – limitations and deviations from the law;

Terminologies associated with absorption measurements; Types of transitions; Factors affecting spectral

characteristics (structural and nonstructural); Effect of conjugation; Wood ward Fieser rule; Photometric

titrations; Instrumentation, applications (in analysis of organic compounds and inorganic complexes),

advantages and limitations of UV Visible spectroscopy; Quantitative analysis of binary mixtures by

simultaneous equation method; Calibration of UV Visible Spectrophotometer as per Pharmacopoeia

8

2 Infra-Red Spectroscopy: Nature of Infra-red radiation, interaction of I.R. radiation with organic

molecules and effects on bonds, molecular or infra-red spectra, berief outline of classical I.R.

instrumentation and interpretation of spectra including sample preparation for spectroscopy, qualitative

interpretation of I.R. spectra, quantitative methods, recent advances in I.R. spectroscopy including FTIR,

ATR, etc.

7

3 Nuclear Magnetic Resonance Spectroscopy: Fundamental principles of NMR (Magnetic properties of

nuclei: applied field and precession: absorption and transition frequency), chemical shifts concept, factors

affecting chemical shift, isotopic nuclei, reference standards; Proton magnetic spectra, their

characteristics, presentation, terms used in describing spectra and their interpretation (signal no., position,

intensity), signal multiplicity phenomena in high resolution PMR; Spin spin coupling, application of

signal splitting and coupling constant data to interpretation of spectra, decoupling and shift reagent

methods. Brief outline of principles of FT-NMR with reference to 13C NMR: Spin-spin and spinlattice

relaxation phenomena, free induction decay (FID), nuclear overhauser enhancement; 13C NMR spectra;

their presentation, characteristics, interpretation, examples and applications. Brief indication of

application of magnetic resonance spectral data of other nuclei by modern NMR instruments,

introduction to 2-D NMR techniques.

8

4 Mass Spectrometry: Basic principles and brief outline of instrumentation, ion formation and types:

molecular ions, meta stable ions, fragmentation processes, fragmentation patterns and fragment

characteristics in relation to parent structure and functional groups, relative abundances of isotopes and

their contribution to characteristic peaks, mass spectrum; its characteristics, presentation and

interpretation, chemical ionization mass spectrometry, GC-MS including recent advances in MS, Fast

atom bombardment mass spectroscopy.

7

5 Flame Photometry (FES), Atomic Emission Spectroscopy (AES) 7

6 Atomic Absorption Spectroscopy (AAS), Fluorescence Spectroscopy 8

Reference Books:

1. Instrumental Methods of Analysis – Scoog and West

2. Spectrometric Identification of Organic Compounds – Silverstein et., al.

3. Instrumental Method of Analysis – Willard Dean & Merrit

4. Text Book of Inorganic Chemistry — A.I. Vogel

5. Pharmaceutical Chemistry Vol. I & Vol. II — Becket and Stanlake

6. Pharmaceutical Chemistry Vol. I & Vol. II — L.G.Chatten

7. Text Book of Pharmaceutical Analysis – K.A. Connors

8. Pharmaceutical Analysis — Hiquchi, Bechmman, Hassan

9. Methods of Drug Analysis — Gearien, Graboski

10. Text Book of BioPharmaceutic Analysis — Robert Smith and James Stewart

11. Pharmaceutical Analysis — Modern methods — Part A and B — Munson James. W

12. Quantitative Analysis of Drugs — Garrot

13. Quantitative Analysis of Drugs in Pharmaceutical Formulations — P. D. Sethi

14. IP/BP/USP

15. Application of Absorption Spectroscopy of Organic Compounds — Dyer

16. Analytical Profiles of Drug Substances — Florey [Volume 13]

17. Spectroscopy of Organic Compound – P. 5. Kalsi, Wiely Eastern Ltd., New Delhi

18. Absorption Spectroscopy of Organic Molecules — V. M. Parikh, Addision — Wesley

19. Publishing Company, London

Syllabus- MUIS


CHE 202 IOC: INDUSTRIAL ORGANIC CHEMISTRY

Unit Content Hrs.

1 Petrochemical

Coal, petroleum, Natural gas, organic chemicals from coal distillation refining of crude oil for

industrial fuels, C1,C2,C3,C4 and aromatic chemicals.

7

2 Non Conventional Energy Sources a) Solar energy: Solar radiation and radiation reaching earth- advantage of solar energy, Conversion

of solar energy to electricity by various ways. Photovoltaic cells- various types, decomposition of

water into elements (Various methods),

b) Wind energy: Wind machines, c) Hydroelectric power, d) Geothermal energy, e) Ocean energy,

Tidal energy, f) Introduction to gobar gas and biomass

g) Introduction to Nuclear fuels, h) Energy from industrial wastes.

General comparison of conventional and non conventional energy sources, Renewable and non

renewable energy sources.

8

3 Oil, Fat & Wax

Classification, vegetable oil, cotton seed oil, animal fats and oil, mineral oil, Hydrocarbon oils,

essential oils, Oils as emollients, silicon oils, waxes, Classification, properties of waxes, Analysis of

oils, Saponification and ester value, Acid and iodine value, Soap and its manufacturing.

7

4 Polymers

Introduction to polymers, Classification of Polymers, Addition polymerization, Free radical chain

polymerization, Ionic polymerization (cationic and anionic), Co-ordination polymerization, Use of

ziegler. Natta catalyst.

8

5 Synthetic dyes

Classification of dyes, anionic, cationic mordant, vat, reactive, disperse, acid, basic and direct dyes,

pigment dyes, nitroso, nitro, azo, acid azo dyes, methyl orange, methyl red, orange-I, anthraquinone

dyes, xanthenes dyes

7

6 Combinatorial chemistry Introduction, combinatorial approaches, combinatorial organic synthesis, methodology, Chemical

Peptide and small molecule libraries, applications, assays and screening of combinatorial libraries,

Introduction to High Throughputs Screening (HTS).

8

Reference Books:

1. Organic Polymer Chemistry by K. J. Saunders.

2. Chemicals from petroleum by Weddams.

3. Industrial Chemicals by Faith, Keyes, Clark.

4. The Chemistry of Synthetic Dyes, Vol.I to VII, by Venkataraman, Academic Press,

5. New York.

6. Polymer science by V.R. Goavarikar.

7. G.L. Patrick, An Introduction to Medicinal Chemistry, 4th

Ed. Oxford University Press, Oxford.

8. Riegel’s Hand-Book of Industrial Chemistry, Ed. by James A. Kent.

9. Industrial Chemistry by B.K.Sharma

Syllabus- MUIS


CHE 203 PCH: PHYSICAL CHEMISTRY - II

Unit Content Hrs.

1 Molecular Spectroscopy

What is spectroscopy? Molecular spectra, Rotational spectra (microwave) of diatomic molecules,

Relative intensities of rotational spectral lines, Determination of bond distance in polyatomic

molecules, Vibrational (IR) spectra of diatomic molecules, Rotation-vibration spectra of diatomic

molecules, Rotation-vibration spectra of polyatomic molecules, Raman spectroscopy, Quantum theory

of Raman scattering, Classical theory of Raman scattering, Rotational-Raman spectrum of diatomic

molecules, Experimental Raman spectroscopy, Numerical

8

2 Macromolecules

Introduction, Classification of polymers, Molecular weight and size, Number and weight average

molecular weight, Sedimentation method, Viscosity method, Light scattering method, Ultra

centrifugation method, The Zimm plote, Kinetics of polymerization, Free-radical chain reactions,

Cationic polymerization, Anionic polymerization, Free-radical co-polymerization, Glass transition

temperature, Importance of glass transition temperature, Polymer’s processing techniques,

Calendaring, Die casting, Rotational casting, Film casting, Numerical

8

3 Photochemistry

Introduction, The Jablonski diagram, The Beer-Lambert law, The Grothus-Draper law, The

photochemical rate law, Kinetics of decomposition of HI, Kinetics of Anthracene reactions,

Photosensitization, Photosynthesis in plants, Photography, Urenile-oxalate actinometer, The Laser and

the Maser, Application of Lasers in chemistry, Numerical

7

4 Electrochemistry

Debye-Huckel theory, Mathematical derivation of Debye-Huckel theory, Tests of Debye-Huckel

theory, The complete Debye-Huckel equation, Debye-Huckel-Bronsted equation, Debye-Huckel-

Onsagar equation, Wien effect, Thermodynamics of electrified interfaces (Lippmann’s equation),

Electrical double layer, Theories of structure of Electrical double layer, Helmoholtz-Perrin theory,

Goug-Chapman theory, Stern’s theory

8

5 Over-potential

Decomposition voltage and its measurement, Polarization, Types of overvoltages, Hydrogen

overvoltage, Oxygen overvoltage, Metal overvoltage, Measurement of overvoltage, Factors affecting

overvoltage, Theories of overvoltage (mechanism of Hydrogen over-voltage), Tafel equation, Butler-

Volmen equation, Diffusion overvoltage

Bioelectrochemistry

Membrane phenomenon, Donnan potential, Case I: The electrolytes in the two solutions have an ion

in common, Case II: The electrolytes on both the sides have no common ion, Case III: One of the

solutions if water alone, Case IV: When one of the electrolytes contains polyvalent ions, Membrane

potential, Applications of Donnan membrane equilibrium, Swelling of gels, Tanning of leather

7

6 Polarography

Polarography and polarogram, Ilkovic equation, Half wave potential equation, Determine the Half

wave potential, Determination of the formula and stability constant of complex metal ion, Effect of

pH on half wave potential, Applications of polarography

7

Syllabus- MUIS


CHE 204 SCA: STATISTICS AND COMPUTER APPLICATIONS

Unit Content Hrs.

1 DOS and Windows

Definition, characteristics, history, computer technology and its application in chemistry

Operating Systems:

MS Word: Addition, Inserting, Deleting , Formatting ,Opening, Saving , Protecting, Locating ,

Managing and Printing of Documents

8

2 MS Excel:

Introduction, calculations in EXCEL, preparation of templates for application in chemistry

Drawing graphs in EXCEL for chemistry

MS Power Point, Computer Fundamentals

Introduction to MS Access and Outlook and pdf documents

Networking & Internet

7

3 Sample and sampling methods

Statistical inference – tests of hypothesis

Introduction, hypothesis, statistical hypothesis, null hypothesis, alternative hypothesis, Example

for all types of tests.

7

4 Correlation and Regression

Introduction, Types of correlation and its methods, Analysis of variance ,Non-parametric tests 8

Reference Books:

1. Windows Vista: Step by Step, Joan Preppernau and Joyce Cox, Prentice Hall of India, New Delhi, 2007

2. Windows Vista: Plain & Simple, Jerry Joyce, and Marianne Moon, Prentice Hall of India, New Delhi, 2007

3. DOS commands in easy steps, Harshad Kotecha, Dreamtech Press, New Delhi, 2000

4. WORD 2000, Guy Hart Davis, BPB Publications, New Delhi, 1999

5. WORD 2000:fast & easy, Diane Koers, BPB Publications, New Delhi, 2000

6. Microsoft WORD 2000:Training Guide, Maria Reid, BPB Publications, New Delhi, 2000

7. Business statistics – J K Sharma, PHI publication

8. Statistical methods – S P Gupta, Sultan Chand & Sons

Syllabus- MUIS


CHE 205 EDM: ENTREPRENEURSHIP DEVELOPMENT

Unit Content Hrs.

1 Entrepreneurial Traits, Types and Significance, Definition, characteristics of Entrepreneurial types,

Quality and function of Entrepreneurs, Role and Importance of Entrepreneurs in economic growth 7

2 Theories of entrepreneurship, Entrepreneur development programme in india, history, support,

objective, stages of performance, Planning and EDP objectives, Target group and selection of center,

Pre training work , Government policy for SSI, Procedures in setting of small scale units: Licensing,

Registration, Financing, Working capital, Financing Institutions.

8

3 Entrepreneur behavior and motivation, Entrepreneur Success in rural areas, Innovation and

Entrepreneur, Role of various institutions in developing entrepreneurship in India, NSIC, SIDCO,

SIDO, SISI , Development Commissioner – TANSI, SIDCO, DIC, Directorate of Industries and

Commerce.

8

4 Ideas: Search, Source, Processing and Inputs requirements, Financing: Source and criteria, Working

capital, Technical assistance, Marketing assistance, Sickness of unit, Preparation of feasibility report,

Legal formalities and documentation, Concessions, rebates, incentives and subsides to small scale

units.

7

Reference Books:

1. Cliffton ,Davis S and Fyfie,david E: “Project feasibilityanalysis”1977 john Wiley, New York

2. Desai, AN: “Entrepreneur & Enviorment”1990.Ashish New Delhi.

3. Drucker Peter: “ Innovation and Enterpreneuership”,1985 Heinemann , London

4. Jain Rajiv: “Planning a small scale industry”1984,S.S.Books Delhi

5. Kumar,SA: “ Entrepreneurship in a small industry” 1990,Discovery New Delhi

6. Mc Clelland ,DC and WINter , WG: “Motivating Economic Achievement”1969, New York

Syllabus- MUIS


CHE 206 PRA: PRACTICAL COURSE – II

MODERN ANALYTICAL TECHNIQUES

1 Demonstration and calibration of UV Visible spectrophotometer

2 Demonstration and calibration of FTIR

3 To determine absorption maximum (λmax) and to study beer’s law

4 To study the effect of solvent on the absorption spectrum of phenol

5 To study the effect of pH on the absorption spectrum of sulphanilamide

6 To study the structural effect of absorption spectrum of different compound

7 To determine absorptivity and molar absorptivity of given compounds by double beam UV Vis.

Spectrophotometer

8 To determine percentage purity of ascorbic acid by UV Visible spectrophotometer

9 To determine isosbestic point of given indicator and to study its use in analysis

10 To determine acid dissociation constant (pKa) of methyl orange by UV Visible spectrophotometry

11 To determine Na+1. K+1, Ca+2 in urine and ORS powder

12 To perform assay of given compound by i) calibration curve method ii) direct comparison method and iii)

regression equation method using UV Visible spectrophotometer

13 To determine % purity of quinine sulphate by fluorescence spectroscopic method and to study quenching effect

of halides

14 To determine concentration of potassium permanganate and potassium dichromate using simultaneous

equations method

15 Structure elucidation by IR, NMR and Mass spectra

16 Colorimetric analysis of aromatic amines by diazotization and coupling using UV Visible spectrophotometer

17 To study hydrolysis of aspirin using UV Visible spectrophotometer

INDUSTRIAL ORGANIC CHEMISTRY PRACTICAL

1 Estimation of Oils and Fats: Saponification and ester value of the given Oil or fat samples, Iodine value and

acid value of given oil or fat samples. Other estimation techniques of Oils and fats

2 Preparation of dyes: Preparation of Azo dyes, dyes obtained by other methods- Fluoroscein, Eosin, Malachite

green, Crystal violet etc and their TLC and MP.

3 Preparation of polymers using different techniques.

4 Practical based on combinatorial techniques- Synthesis of organic compounds by using combinatorial

synthesis, Synthesis with help of parallel synthesizer.

5 Practical based on theory.

PHYSICAL CHEMISTRY PRACTICAL SECTION-I:

1 To study the primary salt effect for kinetics of reaction between K2S2O8 and KI and prove Bronsted-Bierrum

equation

2 To study the reaction between KBrO3 and KI at two different temperature and calculate the energy of

activation

3 To determine equilibrium constant of the reaction KI + I2 = KI3 by distribution method

4 Determine the rate constant for hydrolysis of inversion of canesugar/ d-sucrose using polarimeter

5 Determination of molecular weight of high polymer (polystyrene) by viscosity measurement

PHYSICAL CHEMISTRY PRACTICAL SECTION-II

1 Determine the amount of given mixture of HCl + H2C2O4 using 0.1 N NaOH by pH metry

2 Determine the amount of given mixture of HCl + Acetic acid using 0.1N NaOH by conductometry

3 Determine the amount of given mixture of HCl + Acetic acid using 0.1N NaOH by potentiometry

4 Determine the specifir rotation of given substance (d-Glucose/d-Sucrose) by polarimeter

5 Determine the instability constant of the complex ions between Fe3+

and salicylic acid by Job’s method

(spectrophotometry)

6 Determine the dissociation constant of phenolphthalein indicator by spectrophotometry

7 Determine of an amount of inorganic cations Cu2+

, Co2+

and Ni2+

in the given mixture by circular paper

chromatography

Syllabus- MUIS


SEMESTER-III

CHE 301 OSR: ORGANIC SYNTHESIS AND REACTION MECHANISM

Unit Content Hrs.

1 Study of individual reactions

Arndt Eistert synthesis, Baeyer-Villiger reaction, Baker-Venkatraman reaction, Reformatsky

reaction, Birch reduction, Mannich reaction, Meerwein ponndorf-Verley reduction, Witting

reactions, Willgerdot reaction, Shapiro reaction, Sharpless asymmetric epoxidation.

7

2 Study of rearrangements

Introduction, rearrangement of electron deficient atoms, Allylic rearrangement, Pinacol

Pinacolon rearrangement, wegner-meerwein rearrangement, Benzilic acid rearrangement,

Backmann rearrengment, Hoffman rearrangement, Curtius, Lossen, Schmidt rearrangement,

Favorskii rearrangement, Hoofmann-Maritus rearrangement, Benzidine rearrangement, Fries

rearrengment.

8

3 The disconnection approach (Retrosynthetic analysis)

Guidelines to choose disconnection, Synthons and synthetic equivalents, Functional group

interconversion, the order of events and its guidelines, One-group C-X disconnections, Two-

group C-X disconnections, Chemoselectivity, reversal of polarity, cyclization reactions and

summary of strategy, Stereochemistry of retrosynthesis.

8

4 a).One group C-C disconnections: Alcohols, carbonyl compounds, regioselectivity. Use of

Acetylenes

b).Two-group C-C disconnections: Diels-Alder reactions (stereospecificity, stereoselectivity,

endo-selectivity, regioselectivity), 1,3-Difunctionalised and alpha, beta-unsaturated carbonyl

compounds, 1,5- Difunctionalised compounds, Michael addition and Robinson Annelation.

7

5 Pericyclic Reactions

Pericyclic reactions, stereochemistry of pericyclic reaction, conservation of molecular orbital

symmetry, electrocyclic reactions, cycloaddition, sigmatropic rearrangements, Mobius–Huckel

analysis (PMO approach), correlation diagram method.

7

6 Reagents used in organic synthesis Diazonium salt, Peracids, ECA, EAA, NBS, Malonitrile, DCC, POCl3, Lithium aluminium

hydride, Raney nickel, NaBH4, aluminium tri-t-butoxide, Organolithium compounds,

Organoaluminum comounds.

8

Reference Books:

1. Advanced Organic Chemistry (3rd

ed.) by Carey & Sundberg (Part A & B), Plenum Press.

2. J. Fuhrhop & G. Penzillin, Organic synthesis-Concept, Methods and Starting Material, Verlage VCH.

3. S. Warren, Designing Organic Synthesis, Wiley.

4. W. Carruthers,Some Modren Methods of Organic Synthesis, Cambrige Univ. Press.

5. J. March, Advanced Organic Synthesis: Reaction, Mechanisms and Structure, Wiley.

6. O.P. Agrawal, Reactions and Mechanism, Krishna prakashan, Meerut.

7. S.M.Mukherji and S.P.Singh,Reaction Mechanism in Organic Chemistry, Macmilan

Syllabus- MUIS


CHE 302 OCC: ORGANIC AND COMPUTATIONAL CHEMISTRY

Unit Content Hrs.

1 Computational Chemistry Introduction, Molecular Modeling: Concepts and Methods, Introduction to Cheminformatics, Use

& Prospects of cheminformatics, Representation of Molecules and Chemical Reactions,

Nomenclature of compound, Different types of Notations; SMILES Coding, Structure of Molfiles

and Sdfiles, Libraries and toolkits; Different electronic effects; Structure databases and Reaction

Databases; Searching of Chemical Structure, Full & sub structure search, similarity search; Three

dimensional search methods; Data visualization. Computer Assisted Structure elucidations;

Prediction of NMR, IR and Mass spectra by using Computer, Computer Assisted Synthesis Design.

8

2 Drug design and QSAR Approach

Introduction to drug design; Target Identification and Validation; Lead Finding and Optimization;

Analysis of HTS data; Virtual Screening; Design of Combinatorial Libraries; Introduction to

Ligand-Based and Structure Based Drug design.

QSAR: Basics of Computation of Physical and Chemical Data and structure descriptors;

Parameters - Lipophilicity, Electronic, Stearic factors, Quantitative Models – Hansch analysis, Free

Wilson Analysis, Mixed approach, Other QSAR Approaches, Applications of Hansch Analysis,

Free Wilson Analysis, 3D QSAR approach, Introduction to artificial neural network in QSAR.

8

3 Photochemistry of Carbonyl Compounds

Introduction to photochemical reactions, Intramolecular reactions of carbonyl compounds-

saturated, cyclic and acyclic, β,γ- unsaturated and α,β- unsaturated compounds, cyclohexadienones.

Intermolecular cycloaddition reactions, dimerisations and oxetane formation.

7

4 Green chemistry: Introduction, Principles, Applications.

Microwave Chemistry: Introduction, Fundamental, Apparatus, Advantages, Limitation,

Application, Recent advances.

Nanochemistry: Introduction, Methods, Applications.

7

5 Heterocyclic chemistry of Fused ring system

Introduction, Nomenclature, Biological importance, synthesis and reactions of indole,

benzimidazole, benzthiazole, benztriazole, quinoloine, quinoxaline, purines, xanthenes, Pteridine.

8

6 Structure elucidation

Interpretation of spectra by different spectroscopic techniques i.e. UV, IR, Mass, NMR and

examples.

7

Reference Books:

1. G.L. Patrick, An Introduction to Medicinal Chemistry,4th

Ed. Oxford University Press, Oxford, 2009

2. Ed. M. E. Wolff, Burgers Medicinal chemistry, John Wiley and sons, New York.

3. D. Lednicer, Strategies for organic drug synthesis and design, John Wiley and Sons, USA

4. R.M. Silverstein, G.C. Bassler and T.C. Morrill, Spectrometric Identification of Organic Compounds, John Wiley

5. J.R. Dyer, Application of Spectroscopy of Organic Compounds, Prentice Hall

6. R.J. Abraham, J. Fisher and P. Loftus, Introduction to NMR spectroscopy, Wiley

7. R. M. Acheson : An Introduction to Chemistry of Heterocyclic Compounds (Interscience).

A. R. Katrizky and C. W. Rees: Comprehensive Heterocyclic Chemistry, Pergamon.

8. Green Chemistry Book Series published by the Royal Society of Chemistry

http://www.rsc.org/shop/books/series/81.asp?seriesid=81

Syllabus- MUIS


CHE 303 MCH: MEDICINAL CHEMISTRY

Unit Content Hrs.

1 Drug Receptor Interaction

Basic ligand concept, agonist, antagonist, partial agonist, inverse agonist, Receptor Theories -

Occupancy, Rate & Activation Theories, receptor Binding Assays, determination of B-max and Kd

by transforming data with Hill plot and Scatchered plot.

7

2 Pharmacokinetic and Prodrug

Absorption, Distribution, Metabolism and Excretion in drug discovery.

Prodrug- concept, types and its applications.

7

3 Chemotherapy

Classification, mode of action, SAR and recent advances in given categories of drugs- a)

Antineoplastic, b) Antiviral

Synthesis: Amantadine, Methotraxate, Mechlorethamine, Cyclophosphamide, Melphalan and 6-

Mercaptopurine.

8

4 Antihypertensive and anti diabetic drugs

Introduction, classification, mode of action, SAR and recent advances.

Synthesis: Nifedipine, Amlodipine, Atenolol, Metoprolol, Captopril, Hydralazine, Glipizide,

Metformin, Rosiglitazone, Tolbutamide, Glimipride.

8

5 Drugs affecting the central nervous system: Introduction, classification, mode of action, SAR of Anti Psychotic Drugs, Anti-Depressants,

Sedatives, Hypnotics and Anxiolytic Agents.

Synthesis: Phenobarbital, Hexobarbital, Diazepam, Oxazepam, Alprazolam, Phenytoin,

Ethosuximide, Trimethadione, Chlopromazine, Fentanyl citrate.

8

6 Opiod Analgesics and Non-Opiod Analgesics: Introduction, Classification and Chemistry of Morphine, Pethidine, Benzomorphan, Morphinan,

Synthesis: Pethidine, Methadone.

Non Steroidal Anti-Inflammatory Agents, Anti Gout and DMARDs: Introduction, Classification,

and Synthesis: Paracetamol, Aspirin, Diclofenac, Ibuprofen, Indomethacin, Allopurinol,

Mefenamic acid, Nimesulide, Naproxen.

7

Reference Books:

1. J. H. Block and J.M. Beale Jr., 11th

Ed, Wilson and Giswold’s Textbook of Organic Medicinal and

Pharmaceutical Chemistry, Lippincott Williams & Wilkins, Philadelphia.

2. W. C. Foye, Principles of Medicinal Chemistry, Lea and Febiger, Philadelphia.

3. H. E. Wolff, Burgers Medicinal chemistry, John Wiley and sons, New York.

4. Daniel Lednicer, Strategies for organic drug synthesis and design, John Wiley and Sons, USA

5. B. N. Ladu, H. G. Mandel and E. L. Way, Fundamentals of Drug Metabolism and Disposition, William

and Wilkins, Baltimore.

6. L. Finar. Organic chemistry Vol. I and Vol. II., ELBS/Longman, London.

7. G.L. Patrick, An Introduction to Medicinal Chemistry,4th

Ed. Oxford University Press, Oxford, 2009

8. Burger’s Medicinal Chemistry and Drug Discovery

Syllabus- MUIS


CHE 304 RMD: RESEARCH METHODOLOGY

Unit Content Hrs.

1 Research - meaning, purpose, types (educational, clinical, experimental, historical descriptive, basic,

applied and patent oriented research), & objective of research.

Literature survey-use of library, books and journals – MEDLINE - internet, patent search, and

reprints of articles as a source for literature survey.

8

2 Selecting a problem and preparing research proposals

Methods and tools used in research –Qualitative & quantitative studies, Simple data organization &

descriptive data analysis, Limitation & sources of error, Inquiries in form of questionnaire, etc

Documentation- “How” of documentation, Techniques of documentation, Importance of

documentation, Use of computer packages in documentation.

7

3 The Research Report Paper writing/ thesis writing: Title –title of project with authors name, Abstract-

statement of the problem, background list in brief, purpose & scope, Key Words, Methodology -

subject, apparatus, instrumentation & procedure, Results- tables, graphs, figures & statistical

presentation. Discussion support or non support of hypothesis, practical & theoretical implications,

Conclusion, Acknowledgements, References, Errata, Importance of Spell check for entire project,

Uses of footnotes, Presentation (especially for oral presentation), Introduction and importance, types

of different skills, contained, format of model, poster, gestures, eye contact, facial expressions, stage

fright, volume- pitch, speed, pause & language, visual aids & seating, questionnaire, etc.

7

4 Cost analysis of the project – cost incurred on raw materials, procedure, instrumentations and human

resources. Sources for procurement research grants – international and national agencies, government

and private bodies. Industrial - institution interaction- industrial projects, their feasibility reports,

interaction with industries.

8

Reference Books:

1. Research In Education- John V. Best, John V. Kahn 10th edition, Allyn & Bacon Publisher, 2005

2. Practical Introduction of copyright.by Gavin Mcfarlane, McGraw-Hill Inc.,US, 1982

3. Thesis projects in Science & Engineering – Richard M. Davis, St. Martin's Press, 1979

4. Assignment And Thesis Writing, Jonathan Anderson, Millicent Poole, Juta Academic Publisher, 4th ed, 2008

5. Writing a technical paper- Donald H. Menzel, Mcgraw Hill Higher Education, 1961

6. Effective Business Report Writing –Leland Brown, Prentice Hall College Div, 4th ed., 1961

7. Manual for evaluation of industrial projects, by United Nations Industrial Development Organization.;

Vienna: United Nations Industrial Development Organization, United Nations, 1986

8. Manual for the preparation of industrial feasibility studies, United Nations; Rev Exp Su edition, 1991

9. Biomedical Research by G. Jagadeesh, Sreekant Murthy, Y.K. Gupta and Amitabh Prakash, 2010

Syllabus- MUIS


CHE 305 PRA: PRACTICAL COURSE – III (M. SC. – ORGANIC CHEMISTRY)

ORGANIC SYNTHESIS AND REACTION MECHANISM

1 Synthesis based on Rearrangement and name reactions:

Synthesis of compounds using mannich reaction, Hofmann reaction, benzyl benzilic acid rearrengment,

Pinacol-pinacolone rearrangement, reformatsky reaction, benzidine rearrangement etc

2 Multi steps synthesis:

a) Phthallic anhydride – Phthallimide – Anthranillic acid.

b) Acetophenone – Oxime – Acetanillide.

c) Phthalic anhydride – o-benzoyl benzoic acid - anthraquinone.

d) Aniline- Acetanilide- p-Nitroacetanilide-p-Nitroaniline-p-Dinitrobenzene

e) Acetanilide – p-Bromoacetanilide – p-Bromoaniline.

Other preparations based on theory

ORGANIC AND COMPUTATIONAL CHEMISTRY

1 Computer assisted experiments:

Draw the structure of simple aliphatic, aromatic, heterocyclic compounds with different substituent. Use of

different File format, Find the different notation like SMILE coding etc., Get the correct IUPAC name and

predict the 1HNMR signals with help of computer. Superimposition analysis of compounds

2 Experiments based on QSAR analysis: Descriptors and variables calculations, selection of descriptors

using statistical techniques, QSAR model development and validation

3 Synthesis using green chemistry and microwave techniques

MEDICINAL CHEMISTRY

1. Synthesis of drugs and intermediates: Aspirin, Paracetamol, Hydentoin, sulphanilamide, phenacetine,

Benzocain, Salol, hydroxyl - coumerin, dihydropyrimidenes etc

Syllabus- MUIS


SEMESTER-IV

SUBJECT: CHE 401 PRO: PROJECT WORK

Theory: 18 Hrs./Week Credit: 18