medical nutrition therapy for diseases of the musculoskeletal.pptx
TRANSCRIPT
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Medical Nutrition Therapy forDiseases of the Musculoskeletal and
Nervous System
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Introduction
This topic has combined two important bodilysystems: physical and mental
A review of the anatomy and physioloy of
muscles! bones! and nerves reveals how closelyrelated these structures are"
A decline in conitive functionin is one of the
stronest predictors of impendin mortality
#onitive decline can occur with marked variation
amon individuals and nutrition is one factor that
is believes to be influential
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$actors Affectin the %otential &ole of Diet
Accordin to 'enton ()*+*,
$irst! conitive or brain reserve is said to decrease the
incidence of dementia- i"e" it has been suested that
those with larer brains and better intellectual functionin
have a reater capacity to resist the effects of thebioloical chanes that define dementia
Second! shrinkae of the brain beins in youn adulthood!
suestin that any insidious influence of diet will takeplace from that time onward" The marked decline in the
weiht of the brain associated with advanced dementia
suest it will be easier to slow that decline than repairin
the brain
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Therefore! diet is influential throuhout theentire lifespan and that it affects
neurodevelepment! neurodecline! conitive
performance! and that nutritional ade.uacyplays a crucial part in limitin the
development of dementias
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THE MUSCULOSKELETAL SYSTEM
The musculoskeletal system includes the bones!muscles! and /oints"
The muscles are responsible for movement ofthe body and classified as cardiac (heart
muscle,! skeletal(striated muscle,! and smooth
(non0striated muscles of the astrointestinaltract! blood vessels! and other involuntary
muscles,
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The skeletal system forms the supportin
framework of the body" It consists of axial(skull!
vertebral column! ribs! and sternum, andAppendicular (e1tremities,
The tendons that aid in locomotion attach the
muscles to the skeleton
Disorders of the Musculoskeletal System
Musculoskeletal diseases are those that affectthe bones! /oints! and muscles- some also affect
the internal orans and skin
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&heumatic Diseases
Mostly affects the /oint tissues and causesymptoms of arthritis
The basic structures affected by these
diseases are the connective tissues #onnective tissues are found in every oran
so manifestations of the disease may vary
The diseases are often accompanied by pain!inflammation! and sometimes are disablin
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2arthritis warnin sins
%ersistent pain and stiffness on arisin %ain! tenderness! and swellin in one or more
/oints
&ecurrence of these symptoms especiallywhen they involve more than one /oint
&ecurrent or persistent pain and stiffness in
the neck! lower back! knees! and other /oints"
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3steoarthritis
Also known as degenerativeor hypertrophicarthritis! is the most common form of all /oint
disorders"
A type of arthritis caused by inflammation!breakdown! and eventual loss of cartilae in the
/oints- it can also be caused by ain! heredity!
and in/ury from trauma or disease
3ften observable in elderly and in obese
persons
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Nutrition Therapy
Diet has a little role in the treatment unless thepatient is obese! in which case a low calorie
diet is necessary in order to reduce the strain
on the weiht0bearin /oints or maintain weiht
$or non0obese! a diet ade.uate in protein!
vitamins! minerals! and fluids is sufficient"
In both cases! increased use of fish or fish oil
(not supplements, is recommended forreducin inflammation" Ade.uate intake of 4inc
and vitamin # and 5 are needed"
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6out
Disorder of purine metabolism characteri4ed byelevated uric acid levels in the blood" &esultin
in deposition of urate crystals in the body
It is also characteri4ed by severe pain in the/oints followin an e1ceptionally lare amount of
stress"
Sometimes! the affected /oints swell and
become red and tender" %eople with out have
the tendency to develop kidney stones
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The risk factors are obesity! hih alcohol intake!
hih serum levels of uric acids (which may be
hereditary,! use of some hypertension drus! andhih intake of purines"
Attacks often can be triered by:
Drinkin alcohol especially durin a bine3ver0eatin especially if on a hih purine diet
Minor in/ury to a /oint
Drinkin insufficient fluids
$luid depletion due to certain drus such as diuretics
Attemptin a 7crash diet8
$astin! e"" before surery
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Nutrition Therapy
If the patient is obese! a reduction in weiht isnecessary" $luids should be plentiful to
eliminate urates
A hih carbohydrate and low fat diet alsosupports proper elimination of urates"
9rate crystals are usually formed with hih
sodium load- therefore reduce the intake of salt!
and condiments (patis! toyo! baoon! etc",
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&heumatoid Arthritis (&A,
An autoimmune disease that causes chronic
inflammation of the /oints! tissues around the
/oints! and other orans in the body"
&eferred as a systematic illness and is
sometimes called rheumatoid disease because itcan affect multiple orans
ess common than osteoarthritis but it is more
severe and the cause is unknown" %atients are usually underweiht and occurs
much more in women than in men
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Inflammatory process
The inflammation (called synovitis, results inthe warmth! redness! swellin! and pain"
These are common symptoms of &A"
$irst! the cells of the synovium row and divideabnormally! makin the normally thin synovium
thick 0 resultin a /oint to swell and puff"
As &A proresses! these abnormal synovial
cells bein to invade and destroy the cartilae
and bone within the /oint"
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The surroundin muscles! liaments! andtendons that support and stabili4e the /oint
become weak and unable to work normally"
All of these effects lead to the pain and
deformities often seen in &A
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&A patients; nutritional status is affected throuh
several ways- the inflammation leads to increased
nutritional re.uirements because of the increase inmetabolism
6astritis is often present due to the side effect of
medication The cripplin nature of the disease may affect the
individual;s food intake
The side effects of medications should be
considered and weiht chanes monitored"
The oal of treatment in &A is to reduce /oint
inflammation and pain! ma1imi4e /oint function!
and prevent /oint destruction and deformity"
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The ma/or approach is to control symptoms and prevent
further disability throuh a combination of a proram of
medical! surical! rehabilitative! and dietary services"
The ob/ectives of manaement are the followin:#ontrol pain and inflammation in the /oints and other tissues
usin anti0inflammatory drus and nonsteroidal anti0inflammatory"
Maintenance of /oint function and prevention of deformities
throuh therapeutic e1ercises desined to preserve /oint
motion! muscular strenth! and endurance"&epair of /oints damae throuh surical intervention" This
involves replacin irreversibly damaed /oints! improvin
functional capacity! or preventin damae to normal /oints
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Nutrition Therapy
To date! there is no specific diet that curesarthritis"
#alories should be ade.uate to meet the needs
of the patient for daily activities If patient is obese! a weiht control diet is
desirable" %atient should be at the level of the
recommended dietary allowance"
If patient is in a poor nutritional status or who is
in the inflammatory stae! +"< to )k of protein a
day is advised
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The intake of fish oils has been proven to help
with the inflammation
&ecent reports suested that a Mediterranean
or veetarian diet and=or eatin Bingcherries
helped some cases of &A
ow levels of >itamin '? and >itamin # have
been seen in patients with &A!
and patients with &A usually have lower 4inc
levels than normal individuals
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@uvenile &heumatoid Arthritis (@&A, 3r Stills Diseaseis an autoimmune disorder that
usually occurs in children under +< years old
In addition to the symptoms of arthritis-
splenomealy! lymphadenopathy! leucocytosis!
pyre1ia! rash! and involvement of the cervical spineoccurs"
As the child matures! their condition meres into a
form similar to that of adults" Most children with @&A need medication and
physical therapy
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Nutrition Therapy
There are no data suestin specific food thatcauses or alleviate @&A
Nutritional care can be important in related
problems such as malnutrition! rowth
retardation! weiht loss! obesity! and nutrional
anemia"
Treatments can help to preserve a hih level of
physical and social functionin maintainin aood .uality of life"
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Systemic upus 5rythematosus (S5,
An autoimmune disease in which the immunecomple1es of DNA and anti0DNA produce a
vasculitis causin lesions in many parts of the
body! particularly the /oints! skin! kidney!spleen! pleura! pericardium! endocardium! and
nervous system"
In some cases! a viral infection may producethe immune chanes"
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The most common symptoms are e1treme
fatiue! fever! an acute miratory arthaliaresemblin rheumatic fever and cold! and
numb finers"
There may be skin ulceration because of
abnormal sensitivity to sunliht"
To date! there are five survivors of S5 in the
%hilippines"
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Nutrition Therapy
%otassium supplement is needed if increasedpotassium needs are not met throuh dietary
means"
ih calorie! hih protein soft diet is
recommended durin fever" Diet is further
altered when there is kidney damae"
Some evidences show that a diet low in
saturated fat and supplemented by fish oil maybe helpful"
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Duchenne Muscular Dystrophy (DMD,
DMD is the most common form of musculardystrophy causin muscle deterioration and an
eventual death in men usually before ae B*"
It is a hereditary disease" The ene responsiblefor the production of a key muscle protein
called dystrophin is defective"
The lack of which is associated with complete
muscle corrosion over the first two decades of
life"
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evels of creatine phoshokinase (#%C,! an en4yme
involved in the production of enery for muscle
contraction are markedly elevated in the blood"
Damae to muscle fibers in DMD has already beun
even before birth" owever! visible sins of
weakness are usually evident at )0B years old when
the child beins to stand and walk"
'y the ae of 0
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&espiratory failure is the ma/or life0threatenin
manifestation of the disease"
%atients with trouble in swallowin (dysphaia,
are at hih risk of compromised nutritional status"
3ther neuromuscular disorders can also cause
nutritional problems"
Eeiht ain is evident and nutritional problems in
patients with DMD"
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Nutrition Therapy
An accurate dianosis of the neuromuscular
disorder is essential in order to determine
how best to achieve ade.uate nutrition"
Dietary manaement depends on the natureand scope of the swallowin problem"
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3steopenia and 3steoporosis
Osteopenia0 condition of the bone mass density('MD, less than normal and has no symptoms" The
'MD is not low enouh to be identified as
osteoporosis" Osteoporosis0 multifactorial condition influenced
by a number of enetic! dietary! and lifestyle
factors"
0 proressive decrease in the density of bones!which makes them brittle
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3steoporosis 3ne in four women may develop osteoporosis
%rimarily related to the ain process (older women
are at hiher risk,
Type 1 OsteoporosisF occurs in women after
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#an proress without symptoms and it may not be
years until later fracture takes place"
Most common symptoms are bone fractures in the
spine! hip! or wrist"
3ne sin of vertebral fracture is heiht loss! which
may lead to Dowagers Hump(the disfiurationof the back that results in stooped posture,
Most fre.uent fracture is the hips" It can lead to
chronic pain! disability! and disfiurement" if notcontrolled! may lead to death
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&isk $actors for 3steoporosis
6ender (women are at reater risk, istory of fractures amon elderlyrelatives
5arly menopause (before < y=o, Abnormal absence of menstrual period
Surical menopause (removal ofovaries,
Anore1ia nervosa or 'ulimia
ow bone mass ow testosterone levels in men
$amily history of osteoporosis actose intolerance
%oor nutrition (low calcium and >it" D, #ertain medications (e"" ! e1cessiveamounts of thyroid medication,
ack of weiht0bearin e1ercise Illnesses that impair absorption ofcalcium
#iarette smokin
51cessive alcohol consumption
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In osteoporosis! the oals of manaement are:Stop or reverse bone loss
Increase or stabili4e bone mass! and
&educe fractures! pain! disability! and mortality"
5stroen! calcitonin! and biphosphonates are
medications usually prescribed" 'uildin the bones before the ae of B< can bebest defense aainst developin osteoporosis"
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Nutrition Therapy
Diet alone has not been proven to treatosteoporosis when it has already developed"
$or preventive purposes! a diet with a calcium of
+*** to +)** m durin the rowin years isadvised"
#alcium supplements are used as substitutes if
dairy products and other sources are nottolerated or ade.uately taken
$or elderly women! physical activity is beneficial"
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THE NERVOUS SYSTEM
The nervous system alon with the endocrine
system correlates our ad/ustments and
reactions to internal and e1ternal conditions
as main parts F cranial! central (brain and
spinal cord,! peripheral (peripheral nerves,! and
autonomic
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Malnutrition Induced Neuroloic Disorders
These disorders are usually seen because of
chronic alcoholism! weakenin disease that
affect the astrointestinal tract! starvation!
malnutrition caused by diet inorance! andconditions caused by stress"
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Nutritional Neuropathy
Most common form of nutritional disorder of theperipheral nervous system"
Treatment involves improvement on the overall diet
STA65S
5arly staes
Symmetric impairment of motor and sensory function
&educed or absent refle1 activity affectin the les ate staes
Motor impairment
#omplete paralysis may be elicited
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Vitamin B12 Neuropathy
Described as a proressive deeneration of posteriorand lateral columns of the spinal cord due to a
deficiency in >itamin '+)
%eripheral neuropathy! coldness! numbness! loss of
normal refle1es! weakness of e1tremities! and mental
deterioration are observed
Treatment is achieved by administration of diet used
for pernicious anemia but with increased doses of
cyanocobalamin
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Pyridoxine (Vitamin B6 deficiency Neuropathy
&esults from anti0tuberculosis dru (isonia4id, inadults and dietary deficiency in infants
It may lead to brain damae and mental retardation
in infants" In adults! mood chanes! e1cessive
somnolence! and even psychosis"
Eomen usin oral contraceptives may also
e1perience the same symptoms because it may also
lead to >it" '? deficiency Treatment is throuh intake of lare amounts of
pyrido1ine
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Vitamin ! deficiency
Symptoms are motor0sensory polyneuropathy!
trunkal and limb ata1ia! opthalmopleia! retinal
deeneration! and myopathy"
In severe cases! it may result in neuroa1onaldeeneration and destruction of muscle fibres
Treatment is follow >itamin 5 therapy
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Pellagra (Niacin "eficiency
In the early staes! the patient may be depressed!apathetic! fearful! and apprehensive"
Insomnia! di44iness! and headache are common"
As the disease proresses! psychosischaracteri4ed by confusion! disorientation! and
hallucinations may develop
ater! the patient may lapse into coma" are amounts of niacin about +*0)* m per day
in the presence of ade.uate tryptophan is needed"
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Eernicke0Corsakoff Syndrome
Deficiency of thiamin which causes cardiovascular!central! and peripheral nervous system disturbances"
&esults from inade.uate dietary intake or from
impaired absorption of >itamin '+
Symptoms may be vomitin! diplopia! and
nystamus" $ollowed by mental chanes! apathy!
emotional disturbances! loss of memory!
disorientation! and hallucination Death is common if untreated" If patient survives! the
cerebral corte1 may be damaed
This condition occurs primarily in alcoholics
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Anticonvulsant0Induced >itamin Insufficiency
Nutritional deficiencies may also arise as a result
of usin anticonvulsants usually used for sei4ure
and medications"
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DIETARY EXCESSES
Food Additives 0 artificial colorin! suar! flavor! preservativeare responsible for certain learnin and behavior problems
associated with attention deficit disorder with or without
hyperactivity
0 The red dye ($D# HB, and yellow dye (yellow No"
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0 Damaes the liver! which can interfere with >itamin D
metabolism
0 Alcohol can impair behavior! /udment! memory!
concentration! and coordination"
0 In prenant women! alcohol abuse can lead to $etal
Alcohol Syndrome (baby suffers from birth defects and
mental retardation,
0 Alcoholics often present symptoms of astritis! peptic
ulcer! acute alcoholic hepatitis leadin to cirrhosis and
bronchitis
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0 Alcohol is a dru that burns rapidly in the body" It
produces calories per ram
0 If alcohol is taken in e1cess of
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a!!eineF is a central nervous system stimulant
belonin to a roup called methyl1anthines
0 51cessive caffeine intake can lead to /itterness!aitation! and insomnia
0 Ehen individuals addicted to caffeine withdraw from
it! symptoms (headache! drowsiness! irritability! and
mild depression, bein within +G to ) hours"
0 ow doses (K
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0 %renant women are recommended to reduce
caffeine intake durin early prenancy
0 #affeine is not considered an important risk factorfor osteoporosis
"utrient #xcesses>itamin A F rise in intracranial pressure leadin to
drowsiness! irritability! headache! vomitin! and peelin of
the skin
>itamin D F usually seen in infants! manifestation of
hypercalcemia is evident" In addition! there;s mental
retardation! weakness! fatiue! lassitude! and headache"
>itamin '? F in lare doses! has been shown to cause
sensory neuropathy
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ead F is never a normal part of the body
0 It is widely distributed in our environment (air!
dust and soil! food! and waiter, and has manyuses
0 Small amounts of lead in the body have no bad
health effects0 ead to1icity may cause anemia! kidney damae!
decrease in bacterial and infection resistance! and
nervous system damae in children
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Nutrition Therapy
5vidence shows that diet deficient in calcium!4inc! iron! and copper and associated with
increased absorption of lead in the
astrointestinal tract $luid intake must be ade.uate
>itamin and mineral supplements are also
considered
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Developmental Disabilities with Neuroloical Disorders
&efer to sinificant physical! mental! or sensory
impairment often accompanied by associated
disabilities found in various combinations
Some of these conditions are cerebral palsy!
Down;s syndrome! and fetal alcohol syndrome
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#erebral %alsy (#%,
A type of brain damae resultin from birth in/ury!cerebral hemorrhae! prematurity
It is characteri4ed by two motor disability: atheosis
and spinal paralysis
#theosis $ movement is uncontrollable! the child
needs an increased intake of calories but because of
neuromuscular control may find difficulty in feedin
himself" Mixed Cerebral PalsyF condition when both
spasticity and atheosis may be present
%pastics $ limited activity prone to obesity
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Nutrition Therapy
Swallowin difficulty should be assessed by aspeech patholoist to determine the current stae of
dysphaia
Some may combin oral and tube feedin to supply
all the fluid! calorie! and nutrient re.uirementsaccordin to ae and ender
$or spastic patient! calorie intake must be controlled
to prevent too much weiht ain Maintenance of ood nutritional status and helpin
the child to lead a normal life
$iner foods are en/oyed by some individuals
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Down;s Syndrome (Monolism,
This condition is caused by trisomy of chromosome
)+! directly correlated with the ae of the mother
(above + yrs" old of conception,
#hildren sufferin from this are usually short andoverweiht! with sins of mental retardation that
varies from mild to sever
%atients are characteri4ed by rowth retardation!protrudin tonue! delayed development of oral
refle1es! poor swallowin! and chewin difficulties