medical nutrition therapy for diseases of the musculoskeletal.pptx

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    Medical Nutrition Therapy forDiseases of the Musculoskeletal and

    Nervous System

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    Introduction

    This topic has combined two important bodilysystems: physical and mental

    A review of the anatomy and physioloy of

    muscles! bones! and nerves reveals how closelyrelated these structures are"

    A decline in conitive functionin is one of the

    stronest predictors of impendin mortality

    #onitive decline can occur with marked variation

    amon individuals and nutrition is one factor that

    is believes to be influential

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    $actors Affectin the %otential &ole of Diet

    Accordin to 'enton ()*+*,

    $irst! conitive or brain reserve is said to decrease the

    incidence of dementia- i"e" it has been suested that

    those with larer brains and better intellectual functionin

    have a reater capacity to resist the effects of thebioloical chanes that define dementia

    Second! shrinkae of the brain beins in youn adulthood!

    suestin that any insidious influence of diet will takeplace from that time onward" The marked decline in the

    weiht of the brain associated with advanced dementia

    suest it will be easier to slow that decline than repairin

    the brain

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    Therefore! diet is influential throuhout theentire lifespan and that it affects

    neurodevelepment! neurodecline! conitive

    performance! and that nutritional ade.uacyplays a crucial part in limitin the

    development of dementias

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    THE MUSCULOSKELETAL SYSTEM

    The musculoskeletal system includes the bones!muscles! and /oints"

    The muscles are responsible for movement ofthe body and classified as cardiac (heart

    muscle,! skeletal(striated muscle,! and smooth

    (non0striated muscles of the astrointestinaltract! blood vessels! and other involuntary

    muscles,

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    The skeletal system forms the supportin

    framework of the body" It consists of axial(skull!

    vertebral column! ribs! and sternum, andAppendicular (e1tremities,

    The tendons that aid in locomotion attach the

    muscles to the skeleton

    Disorders of the Musculoskeletal System

    Musculoskeletal diseases are those that affectthe bones! /oints! and muscles- some also affect

    the internal orans and skin

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    &heumatic Diseases

    Mostly affects the /oint tissues and causesymptoms of arthritis

    The basic structures affected by these

    diseases are the connective tissues #onnective tissues are found in every oran

    so manifestations of the disease may vary

    The diseases are often accompanied by pain!inflammation! and sometimes are disablin

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    2arthritis warnin sins

    %ersistent pain and stiffness on arisin %ain! tenderness! and swellin in one or more

    /oints

    &ecurrence of these symptoms especiallywhen they involve more than one /oint

    &ecurrent or persistent pain and stiffness in

    the neck! lower back! knees! and other /oints"

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    3steoarthritis

    Also known as degenerativeor hypertrophicarthritis! is the most common form of all /oint

    disorders"

    A type of arthritis caused by inflammation!breakdown! and eventual loss of cartilae in the

    /oints- it can also be caused by ain! heredity!

    and in/ury from trauma or disease

    3ften observable in elderly and in obese

    persons

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    Nutrition Therapy

    Diet has a little role in the treatment unless thepatient is obese! in which case a low calorie

    diet is necessary in order to reduce the strain

    on the weiht0bearin /oints or maintain weiht

    $or non0obese! a diet ade.uate in protein!

    vitamins! minerals! and fluids is sufficient"

    In both cases! increased use of fish or fish oil

    (not supplements, is recommended forreducin inflammation" Ade.uate intake of 4inc

    and vitamin # and 5 are needed"

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    6out

    Disorder of purine metabolism characteri4ed byelevated uric acid levels in the blood" &esultin

    in deposition of urate crystals in the body

    It is also characteri4ed by severe pain in the/oints followin an e1ceptionally lare amount of

    stress"

    Sometimes! the affected /oints swell and

    become red and tender" %eople with out have

    the tendency to develop kidney stones

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    The risk factors are obesity! hih alcohol intake!

    hih serum levels of uric acids (which may be

    hereditary,! use of some hypertension drus! andhih intake of purines"

    Attacks often can be triered by:

    Drinkin alcohol especially durin a bine3ver0eatin especially if on a hih purine diet

    Minor in/ury to a /oint

    Drinkin insufficient fluids

    $luid depletion due to certain drus such as diuretics

    Attemptin a 7crash diet8

    $astin! e"" before surery

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    Nutrition Therapy

    If the patient is obese! a reduction in weiht isnecessary" $luids should be plentiful to

    eliminate urates

    A hih carbohydrate and low fat diet alsosupports proper elimination of urates"

    9rate crystals are usually formed with hih

    sodium load- therefore reduce the intake of salt!

    and condiments (patis! toyo! baoon! etc",

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    &heumatoid Arthritis (&A,

    An autoimmune disease that causes chronic

    inflammation of the /oints! tissues around the

    /oints! and other orans in the body"

    &eferred as a systematic illness and is

    sometimes called rheumatoid disease because itcan affect multiple orans

    ess common than osteoarthritis but it is more

    severe and the cause is unknown" %atients are usually underweiht and occurs

    much more in women than in men

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    Inflammatory process

    The inflammation (called synovitis, results inthe warmth! redness! swellin! and pain"

    These are common symptoms of &A"

    $irst! the cells of the synovium row and divideabnormally! makin the normally thin synovium

    thick 0 resultin a /oint to swell and puff"

    As &A proresses! these abnormal synovial

    cells bein to invade and destroy the cartilae

    and bone within the /oint"

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    The surroundin muscles! liaments! andtendons that support and stabili4e the /oint

    become weak and unable to work normally"

    All of these effects lead to the pain and

    deformities often seen in &A

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    &A patients; nutritional status is affected throuh

    several ways- the inflammation leads to increased

    nutritional re.uirements because of the increase inmetabolism

    6astritis is often present due to the side effect of

    medication The cripplin nature of the disease may affect the

    individual;s food intake

    The side effects of medications should be

    considered and weiht chanes monitored"

    The oal of treatment in &A is to reduce /oint

    inflammation and pain! ma1imi4e /oint function!

    and prevent /oint destruction and deformity"

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    The ma/or approach is to control symptoms and prevent

    further disability throuh a combination of a proram of

    medical! surical! rehabilitative! and dietary services"

    The ob/ectives of manaement are the followin:#ontrol pain and inflammation in the /oints and other tissues

    usin anti0inflammatory drus and nonsteroidal anti0inflammatory"

    Maintenance of /oint function and prevention of deformities

    throuh therapeutic e1ercises desined to preserve /oint

    motion! muscular strenth! and endurance"&epair of /oints damae throuh surical intervention" This

    involves replacin irreversibly damaed /oints! improvin

    functional capacity! or preventin damae to normal /oints

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    Nutrition Therapy

    To date! there is no specific diet that curesarthritis"

    #alories should be ade.uate to meet the needs

    of the patient for daily activities If patient is obese! a weiht control diet is

    desirable" %atient should be at the level of the

    recommended dietary allowance"

    If patient is in a poor nutritional status or who is

    in the inflammatory stae! +"< to )k of protein a

    day is advised

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    The intake of fish oils has been proven to help

    with the inflammation

    &ecent reports suested that a Mediterranean

    or veetarian diet and=or eatin Bingcherries

    helped some cases of &A

    ow levels of >itamin '? and >itamin # have

    been seen in patients with &A!

    and patients with &A usually have lower 4inc

    levels than normal individuals

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    @uvenile &heumatoid Arthritis (@&A, 3r Stills Diseaseis an autoimmune disorder that

    usually occurs in children under +< years old

    In addition to the symptoms of arthritis-

    splenomealy! lymphadenopathy! leucocytosis!

    pyre1ia! rash! and involvement of the cervical spineoccurs"

    As the child matures! their condition meres into a

    form similar to that of adults" Most children with @&A need medication and

    physical therapy

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    Nutrition Therapy

    There are no data suestin specific food thatcauses or alleviate @&A

    Nutritional care can be important in related

    problems such as malnutrition! rowth

    retardation! weiht loss! obesity! and nutrional

    anemia"

    Treatments can help to preserve a hih level of

    physical and social functionin maintainin aood .uality of life"

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    Systemic upus 5rythematosus (S5,

    An autoimmune disease in which the immunecomple1es of DNA and anti0DNA produce a

    vasculitis causin lesions in many parts of the

    body! particularly the /oints! skin! kidney!spleen! pleura! pericardium! endocardium! and

    nervous system"

    In some cases! a viral infection may producethe immune chanes"

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    The most common symptoms are e1treme

    fatiue! fever! an acute miratory arthaliaresemblin rheumatic fever and cold! and

    numb finers"

    There may be skin ulceration because of

    abnormal sensitivity to sunliht"

    To date! there are five survivors of S5 in the

    %hilippines"

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    Nutrition Therapy

    %otassium supplement is needed if increasedpotassium needs are not met throuh dietary

    means"

    ih calorie! hih protein soft diet is

    recommended durin fever" Diet is further

    altered when there is kidney damae"

    Some evidences show that a diet low in

    saturated fat and supplemented by fish oil maybe helpful"

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    Duchenne Muscular Dystrophy (DMD,

    DMD is the most common form of musculardystrophy causin muscle deterioration and an

    eventual death in men usually before ae B*"

    It is a hereditary disease" The ene responsiblefor the production of a key muscle protein

    called dystrophin is defective"

    The lack of which is associated with complete

    muscle corrosion over the first two decades of

    life"

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    evels of creatine phoshokinase (#%C,! an en4yme

    involved in the production of enery for muscle

    contraction are markedly elevated in the blood"

    Damae to muscle fibers in DMD has already beun

    even before birth" owever! visible sins of

    weakness are usually evident at )0B years old when

    the child beins to stand and walk"

    'y the ae of 0

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    &espiratory failure is the ma/or life0threatenin

    manifestation of the disease"

    %atients with trouble in swallowin (dysphaia,

    are at hih risk of compromised nutritional status"

    3ther neuromuscular disorders can also cause

    nutritional problems"

    Eeiht ain is evident and nutritional problems in

    patients with DMD"

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    Nutrition Therapy

    An accurate dianosis of the neuromuscular

    disorder is essential in order to determine

    how best to achieve ade.uate nutrition"

    Dietary manaement depends on the natureand scope of the swallowin problem"

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    3steopenia and 3steoporosis

    Osteopenia0 condition of the bone mass density('MD, less than normal and has no symptoms" The

    'MD is not low enouh to be identified as

    osteoporosis" Osteoporosis0 multifactorial condition influenced

    by a number of enetic! dietary! and lifestyle

    factors"

    0 proressive decrease in the density of bones!which makes them brittle

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    3steoporosis 3ne in four women may develop osteoporosis

    %rimarily related to the ain process (older women

    are at hiher risk,

    Type 1 OsteoporosisF occurs in women after

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    #an proress without symptoms and it may not be

    years until later fracture takes place"

    Most common symptoms are bone fractures in the

    spine! hip! or wrist"

    3ne sin of vertebral fracture is heiht loss! which

    may lead to Dowagers Hump(the disfiurationof the back that results in stooped posture,

    Most fre.uent fracture is the hips" It can lead to

    chronic pain! disability! and disfiurement" if notcontrolled! may lead to death

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    &isk $actors for 3steoporosis

    6ender (women are at reater risk, istory of fractures amon elderlyrelatives

    5arly menopause (before < y=o, Abnormal absence of menstrual period

    Surical menopause (removal ofovaries,

    Anore1ia nervosa or 'ulimia

    ow bone mass ow testosterone levels in men

    $amily history of osteoporosis actose intolerance

    %oor nutrition (low calcium and >it" D, #ertain medications (e"" ! e1cessiveamounts of thyroid medication,

    ack of weiht0bearin e1ercise Illnesses that impair absorption ofcalcium

    #iarette smokin

    51cessive alcohol consumption

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    In osteoporosis! the oals of manaement are:Stop or reverse bone loss

    Increase or stabili4e bone mass! and

    &educe fractures! pain! disability! and mortality"

    5stroen! calcitonin! and biphosphonates are

    medications usually prescribed" 'uildin the bones before the ae of B< can bebest defense aainst developin osteoporosis"

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    Nutrition Therapy

    Diet alone has not been proven to treatosteoporosis when it has already developed"

    $or preventive purposes! a diet with a calcium of

    +*** to +)** m durin the rowin years isadvised"

    #alcium supplements are used as substitutes if

    dairy products and other sources are nottolerated or ade.uately taken

    $or elderly women! physical activity is beneficial"

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    THE NERVOUS SYSTEM

    The nervous system alon with the endocrine

    system correlates our ad/ustments and

    reactions to internal and e1ternal conditions

    as main parts F cranial! central (brain and

    spinal cord,! peripheral (peripheral nerves,! and

    autonomic

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    Malnutrition Induced Neuroloic Disorders

    These disorders are usually seen because of

    chronic alcoholism! weakenin disease that

    affect the astrointestinal tract! starvation!

    malnutrition caused by diet inorance! andconditions caused by stress"

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    Nutritional Neuropathy

    Most common form of nutritional disorder of theperipheral nervous system"

    Treatment involves improvement on the overall diet

    STA65S

    5arly staes

    Symmetric impairment of motor and sensory function

    &educed or absent refle1 activity affectin the les ate staes

    Motor impairment

    #omplete paralysis may be elicited

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    Vitamin B12 Neuropathy

    Described as a proressive deeneration of posteriorand lateral columns of the spinal cord due to a

    deficiency in >itamin '+)

    %eripheral neuropathy! coldness! numbness! loss of

    normal refle1es! weakness of e1tremities! and mental

    deterioration are observed

    Treatment is achieved by administration of diet used

    for pernicious anemia but with increased doses of

    cyanocobalamin

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    Pyridoxine (Vitamin B6 deficiency Neuropathy

    &esults from anti0tuberculosis dru (isonia4id, inadults and dietary deficiency in infants

    It may lead to brain damae and mental retardation

    in infants" In adults! mood chanes! e1cessive

    somnolence! and even psychosis"

    Eomen usin oral contraceptives may also

    e1perience the same symptoms because it may also

    lead to >it" '? deficiency Treatment is throuh intake of lare amounts of

    pyrido1ine

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    Vitamin ! deficiency

    Symptoms are motor0sensory polyneuropathy!

    trunkal and limb ata1ia! opthalmopleia! retinal

    deeneration! and myopathy"

    In severe cases! it may result in neuroa1onaldeeneration and destruction of muscle fibres

    Treatment is follow >itamin 5 therapy

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    Pellagra (Niacin "eficiency

    In the early staes! the patient may be depressed!apathetic! fearful! and apprehensive"

    Insomnia! di44iness! and headache are common"

    As the disease proresses! psychosischaracteri4ed by confusion! disorientation! and

    hallucinations may develop

    ater! the patient may lapse into coma" are amounts of niacin about +*0)* m per day

    in the presence of ade.uate tryptophan is needed"

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    Eernicke0Corsakoff Syndrome

    Deficiency of thiamin which causes cardiovascular!central! and peripheral nervous system disturbances"

    &esults from inade.uate dietary intake or from

    impaired absorption of >itamin '+

    Symptoms may be vomitin! diplopia! and

    nystamus" $ollowed by mental chanes! apathy!

    emotional disturbances! loss of memory!

    disorientation! and hallucination Death is common if untreated" If patient survives! the

    cerebral corte1 may be damaed

    This condition occurs primarily in alcoholics

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    Anticonvulsant0Induced >itamin Insufficiency

    Nutritional deficiencies may also arise as a result

    of usin anticonvulsants usually used for sei4ure

    and medications"

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    DIETARY EXCESSES

    Food Additives 0 artificial colorin! suar! flavor! preservativeare responsible for certain learnin and behavior problems

    associated with attention deficit disorder with or without

    hyperactivity

    0 The red dye ($D# HB, and yellow dye (yellow No"

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    0 Damaes the liver! which can interfere with >itamin D

    metabolism

    0 Alcohol can impair behavior! /udment! memory!

    concentration! and coordination"

    0 In prenant women! alcohol abuse can lead to $etal

    Alcohol Syndrome (baby suffers from birth defects and

    mental retardation,

    0 Alcoholics often present symptoms of astritis! peptic

    ulcer! acute alcoholic hepatitis leadin to cirrhosis and

    bronchitis

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    0 Alcohol is a dru that burns rapidly in the body" It

    produces calories per ram

    0 If alcohol is taken in e1cess of

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    a!!eineF is a central nervous system stimulant

    belonin to a roup called methyl1anthines

    0 51cessive caffeine intake can lead to /itterness!aitation! and insomnia

    0 Ehen individuals addicted to caffeine withdraw from

    it! symptoms (headache! drowsiness! irritability! and

    mild depression, bein within +G to ) hours"

    0 ow doses (K

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    0 %renant women are recommended to reduce

    caffeine intake durin early prenancy

    0 #affeine is not considered an important risk factorfor osteoporosis

    "utrient #xcesses>itamin A F rise in intracranial pressure leadin to

    drowsiness! irritability! headache! vomitin! and peelin of

    the skin

    >itamin D F usually seen in infants! manifestation of

    hypercalcemia is evident" In addition! there;s mental

    retardation! weakness! fatiue! lassitude! and headache"

    >itamin '? F in lare doses! has been shown to cause

    sensory neuropathy

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    ead F is never a normal part of the body

    0 It is widely distributed in our environment (air!

    dust and soil! food! and waiter, and has manyuses

    0 Small amounts of lead in the body have no bad

    health effects0 ead to1icity may cause anemia! kidney damae!

    decrease in bacterial and infection resistance! and

    nervous system damae in children

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    Nutrition Therapy

    5vidence shows that diet deficient in calcium!4inc! iron! and copper and associated with

    increased absorption of lead in the

    astrointestinal tract $luid intake must be ade.uate

    >itamin and mineral supplements are also

    considered

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    Developmental Disabilities with Neuroloical Disorders

    &efer to sinificant physical! mental! or sensory

    impairment often accompanied by associated

    disabilities found in various combinations

    Some of these conditions are cerebral palsy!

    Down;s syndrome! and fetal alcohol syndrome

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    #erebral %alsy (#%,

    A type of brain damae resultin from birth in/ury!cerebral hemorrhae! prematurity

    It is characteri4ed by two motor disability: atheosis

    and spinal paralysis

    #theosis $ movement is uncontrollable! the child

    needs an increased intake of calories but because of

    neuromuscular control may find difficulty in feedin

    himself" Mixed Cerebral PalsyF condition when both

    spasticity and atheosis may be present

    %pastics $ limited activity prone to obesity

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    Nutrition Therapy

    Swallowin difficulty should be assessed by aspeech patholoist to determine the current stae of

    dysphaia

    Some may combin oral and tube feedin to supply

    all the fluid! calorie! and nutrient re.uirementsaccordin to ae and ender

    $or spastic patient! calorie intake must be controlled

    to prevent too much weiht ain Maintenance of ood nutritional status and helpin

    the child to lead a normal life

    $iner foods are en/oyed by some individuals

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    Down;s Syndrome (Monolism,

    This condition is caused by trisomy of chromosome

    )+! directly correlated with the ae of the mother

    (above + yrs" old of conception,

    #hildren sufferin from this are usually short andoverweiht! with sins of mental retardation that

    varies from mild to sever

    %atients are characteri4ed by rowth retardation!protrudin tonue! delayed development of oral

    refle1es! poor swallowin! and chewin difficulties