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Faculty of MedicineFaculty of MedicineAin Shams UniversityAin Shams University

Postgraduate StudiesPostgraduate Studies

Medical Doctorate inMedical Physiologyفي الدكتوراه درجة

الطبية الفسيولوجياProgram Code: PHY 700

Program Guide and Logbook

C a n d i d a t e C u r r i c u l u m v i t a e

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Filled by post graduate authorities

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TABLE OF CONTENTS:

4

Training

[any other training that will be useful in your job]

PageI – Welcome Statement 6II - Mission Statement 6 III–Senior supervisor 6 IV – Program specifications 7 1 - Basic Information 2 - Professional Information 7 3 – Academic standards 9 4 - Curriculum structure and contents 9 5 - Program courses: 9 6. Program admission requirements: 10 7. Regulation for progression and program completion 11 8. Appendiac course specifications

o Medical physiology course specification 14o Cardiac electrophysiology 29o Platelet physiology 33 o Physiology of obesity & adipose tissue 36o Physiology of aviation and space 40o Advanced pulmonary function tests & respiratory failure. 44 o Brain role in body homeostasis . 48

V - General information 52VI – Your log book 54 1 – Introduction 54 2 – Supervisors 54 3 - Tables for training records 54 4 – Log book preview 60VII - Head of department approval for the exam entry 61

Detachable forms: VIII – Thesis follow up 62IX - Evaluation forms 63

I – Welcome Statement:The Department of Physiology welcomes you to the Medical Doctorate

degree in Medical Physiology. As a department we are committed to medical student education and continuously strive to improve your educational experience.

5

This handbook presents information guide and logbook activity of the Medical Doctorate degree in Medical Physiology administered by the Physiology department, Faculty of Medicine, Ain Shams University.

II - Mission Statement:The mission of the Faculty of Medicine, Ain Shams University is

• The preparation of a competent graduate, who is able to compete on both national and regional levels, capable of life long learning, training and tutoring, while adhering to the codes of practice of medical health services and ethics.

• The college as well, seeks continuous development of programs and courses. It also enhances expansion of applied scientific research and health programs for community services and environmental development.

The mission of this degree is Preparation of a trained researcher and lecture in medical physiology capable of following standards of medical education & conducting scientific research with updated technical skills in his speciality.

III – Senior Supervisor Prof.---------------------------------------------------------------------------------------------E-mail:

------------------------------

6

IV – Program SpecificationsA- Basic Information1. Program title: Medical Doctorate degree in Medical

physiology2. Program type: Single Double Multiple3. Faculty :Faculty of Medicine: Ain Shams University4. Department ;Physiology Department5. Assistant co-ordinator Dr. Nehal M. Bahgat6. Co-ordinator Dr. Bataa M. elkafoury Dr. nehal M. Bahgat Gamil 7. Last date of program approval:……………………………………………………………

B- Professional Information:1. Program aims:

a- To enable the candidate to relate organ functions at cellular and molecular level in health and disease states.

b- To enable the candidate to integrate regulatory mechanisms of different body functions in health & disease states

c- To enable the candidate to teach different physiology topics in tutorials and lectures.

d- To update candidate knowledge and practical skills e- To enable the candidate to apply physiological principles ,hypothesize and

carrying out a thesis

2. Intended learning outcomes (ILOs):a. Knowledge and understanding:

By the end of the program the candidate will be able to; a1-Relate functions of different body systems and the

mechanisms involved in its regulation at cellular and molecular basis. a2-Describe how different body functions are integrated to maintain homeostasis. a3-Explain disturbed body functions at cellular & molecular level.

7

b. Intellectual capabilities: By the end of the program the candidate will be able to: b1- Analyze the given information. b2- Conclude the outcome of a disturbed body function b3- Argue problems through case study and choose the best from multiple . b4- Hypothesize and experiment physiological issues. c. Professional and practical skills :. By the end of the program the candidate will be able to: c1- carry out advanced experiments in practical physiology

Isolated perfused hearts (rabbit & frog). Recording cardiovascular parameters in animals under various

conditions Pulmonary function tests assessement. Skeletal muscle contraction assessement. Smooth muscle contraction Neuromuscular transmission assessement Autonomic functions in humans EMG & nerve conduction velocity Study of platelet aggregation

c2-To use different equipments in physiology department for scientific research.

d. General and transferable skills:. By the end of the program the candidate will be able to:

d1-Communicate with medical students in tutorials and lectures.

d2-To cmmunicate with staff members in physiology depart- ent and otherdepartments in seminars and scientific conferences.

d3- Present seminars, papers in physiology department and medical conferences.

3 . Academic standards: (Benchmarks) Academic reference standards guided by University of Cambridge programme specifications.

4. Curriculum structure and contents; 4a- Program duration: 2.5 years.

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4b-Program structure:-الساعات المعتمدة

الكود المقررات الدراسية

العلمي البحث أساسيات دورة متطلبا ت

الكليةيوجد ال الجزء

األول15 الرسالة12106

PHY7001

PHY7002

التطبيقية .1 و العامة النظرية المقررات( محاضرات(

التخصصية .2 و المتقدمة النظرية المقرراتدراسية( حلقات و ندوات

التجريبية .3 النماذج و العملية المقررات

الجزءالثاني

2E7003E7004E7005E7006E7007E7008

من واحدة مادة اختيار :يتمالقلب .1 كهروفسيولوجيةالدم .2 صفائح فسيولوجياالدهني .3 النسيج و السمنة فسيولوجيالبجوي .4 الفضاء و الطيران فسيولوجياو .5 التنفس لوظائف المتقدمة اإلختبارات

التنفسي الفشلالجسم .6 عناصر اتزان في المخ دور

المقررا ت

اإلختيارية

15 كراسةاألنشطة

60 المجموع

1. Program courses:5.1- Year of programme -1st year semester -1&2a-Compulsory

Code No.

Course title Total hours

Lect

Lab

PHY7001

General theoretical & applied courses.

150

5.2- Year of programme -2nd & ½ semester 3,4,5 a-Compulsory

9

Code No

Course Title Total Hours

Lect Lab

PHY7002 1. Advanced & specialized theoretical courses.

2.3. Practical courses &

Experimental models Isolated perfused hearts (rabbit

& frog). Recording cardiovascular

parameters in animals under various conditions

Pulmonary function tests assessement.

Skeletal muscle contraction assessement.

Smooth muscle contraction Neuromuscular transmission

assessement Autonomic functions in humans EMG & nerve conduction

velocity Study of platelet aggregation

180

180

b-electiveCode No.

Course title Total HoursLec Lab

E7003

E7004

E7005

E7006

E7007

E7008

Crdiac electrophysiology

Platelet physiology

Physiology of obesity and adipose tissue

Physiology of aviation

Advanced pulmonary function tests &respiratory failure.

30

10

Brain role in Homeostatsis

6. Program admission requirements:

الدكتوراه): :-7المادة ( درجة على للحصول الطالب لقيد يشترطالمواد -1 إحدى أو التخصص مادة في الماجستير درجة على حاصال يكون أن

لها معادلة درجة على أو المصرية الجامعات إحدى من بها المتصلة األساسية

الدراسة -2. متطلبات على العمل جهة ومصاريف- 9. موافقة الرسوم تسديد

الملحق ) في المطلوبة المستندات وإستيفاء األجهزة وإستهالك 0( 2التدريب

دخول- 10 قبل األقل على دراسية فصول خمس لمدة للدراسة التفرغ

. احد فى األقل على المدة لنفس التدريب يتم أن ويمكن الثاني الجزء امتحان

الشروط أستيفاء بعد الكلية من المعتمدة العلمية المراكز أو المستشفيات

. المختصة األقسام تحددها التى7. Regulation for progression and program completion

يوليو : ): 8مادة ( أول من األولى العام فى مرتين الدكتوراه لدرجات التسجيل يتم

ديسمبر آخر حتى نوفمبر أول من والثانية أغسطس آخر 0حتى

منهما ): 9مادة ( كل مدة دراسيين فصلين على جامعى عام كل فى الدراسة توزع

. مع . فبراير منصف فى الثانى ويبدا أكتوبر أول فى االول يبدا اسبوعا عشر خمسة

الدراسى . للفصل التسجيل يتم و اسابيع ستة لمدة مكثف صيفى دراسى فصل تنظيم

. المسجلة المقررات حسب الشروط إستيفاء بعد االقل على بدايته من اسبوعين قبل

عن الواحد الفصل فى الدراسى العبء يزيد أن . 6والينبغى ويجوز معتمدة ساعات

او ) بالحذف الدراسى الفصل بداية من اسبوعين خالل المقررات تعديل للطالب

احتسابه (. دون المقرارت احد من اسابيع سته خالل االنسحاب له يجوز كما االضافة

. فيه راسبافصول ) ): 17مادة ( ست شهرا وثالثون ستة الدكتوراه على للحصول الدراسة مدة

للساعات( طبقا بالقسم متكامال تدريبيا برنامجا الطالب خاللهم يجتاز دراسية

متابعة كتيب فى منه المطلوب خاللها ويستوفى الخامس بالباب الموضحة المعتمدة

م األنشطة المطلوب أرباع ثالثة إستيفاء قبل اإلمتحان بدخول له يسمح من وال نه

المعتمدة . الساعات

11

للدكتوراه ): 18مادة ( األول الجزء في الدراسة وجد مدة يجتاز إن واحد دراسي فصل

الجزء في للدراسة لإلنتقال بالكامل فيه النجاح يشترط وال إمتحانا الطالب بعده

الجامعية المستشفيات بإحدى التدريب خاللها ويشترط المراكز الثاني المعتمدةأو

الخارج أو بالداخل سواء بالكلية العليا الدراسات ولجنة القسم يتم من أن على

المعتمدة للساعات طبقا الدراسة . إستكمال

الرسالة ): 19مادة ( موضوع بتسجيل الدكتوراه لدرجة الدارس القيد يقوم للدرجةمع

لها توال يخصص وال للدرجة التسجيل على عامين مرور قبل الرسالة مناقشة جوز

درجات.

التسجيل ): 20مادة ( قبل الجامعة متطلبات بإستيفاء الدكتوراه لدرجة الدارس يقوم

الكلية الرسالة ومتطلبات الثاني ومناقشة الجزء إمتحان دخول ومتطلبات .قبل

مجموع ) اإلنجليزية اللغة في التويفل شهادة على الحصول هي (550الجامعة درجة

فى بالكلية العليا الدراسات لجنة من معتمدة دورات حضور هى الكلية ومتطلبات

تحددها خاصة إختبارات إجتياز أو الطبي واإلحصاء الطبية والدراسات التخطيط مجال

اللجنة. الدكتوراه ): 21مادة ( لدراسة المعتمدة و الساعات ست منها ساعة تسعون و ست

ستون يضاف و الماجستير اثناء دراستهم تمت ساعة األقل معتمدة ساعة ثالثون على

متابعة لكتيب ساعة عشرة خمس منها ساعة األنشطة ويخصص عشرة وخمس

األول للجزء األقل على ساعات وست وجد للرسالة . إن

): 22مادة ( بناءا الجامعة لمجلس ويجوز سنوات خمس الدكتوراه لدرجة القيد مدة

مجلس طلب بعد بالكلية العليا الدراسات لجنة موافقة وبعد الكلية مجلس طلب على

بإضافة السماح الطالب على المشرفين جميع من سنوية تقارير إلى وإستنادا القسم

واحد .عام الدكتوراه درجة على للحصول القيد تاريخ من سنوات ثمان أقصى وبحدا ت): 23مادة ( ب لتزم المرتبطة المواد أقسام مع باألشتراك المعنية وضعالقسام

وقصيرة طويلة أسئلة من المختلفة التقييم وسائل تشمل موضوعية إمتحانات

أن على المختلفة المهارات تقيس مقننة إكلينيكية وإختبارات ، اإلختيارات ومتعددة

بالكلية . العليا الدراسات لجنة من وتعتمد ذلك تفاصيل المناهج كراسة تشملللدكتوراه ): 24مادة ( النهائى االمتحان درجات منها 1500مجموع درجة 300درجة

. الف المعدل اليها ويضاف وجد إن األول يوازى صللجزء بما التراكمى . 400لى

12

إمتحان ): 25مادة ( ويعقد عام كل من ونوفمبر أكتوبر في األول الدور إمتحان يعقد

. عام كل من ومايو أبريل فى الثاني الدورعلى ):26مادة ( الحصول بعد الدكتوراه مواد فى النجاح درجة% 60يكون من

. حدة على كل والشفوي واالكلينيكى والعملي التحريري Assessment Schedule and Weighing of Assessments:

Item Mark

Poin

ts

GPA

sc

oreحالة

ب الطال St

uden

t

During semeste

r

End of semeste

rTotal

Second semester 100 100Third semester 100 100Fourth semester 100 100Fifth semester 100 100Sixth semesterFinal exam

Written 900

1500 1500Oral 150Practical /Clinical 450

Total 400 1500 1900

للنقاط: طبقا الطالب درجات تعادل التالى ملحوظة الوجه على : 4:فأكثر % 90 -1

نقاط

A

أقل% 85من- 2 حتى %90من

:3.67 نقاط

A-

أقل% 80من -3 حتى%85من

:3.33 نقا

B+

13

طأقل% 75من -4 حتى

%80من :3.00

نقاط

B


:2.67 نقاط

B-


:2.33 نقاط

C+

أقل% 62من- 7 حتى%65من

:2.00 نقاط

C


:1.67 نقاط

C-

من -9 Fصفر:%60أقل

للدكتوراه النهائى االمتحان درجات منها 1500مجموع إن 300درجة األول للجزء درجةالف. المعدل إليها ويضاف يوازى صوجد بما التراكمى العالى 300لى للدبلوم درجة

و . 400والماجستير للدكتوراه درجةالفصلى ) المعدل حساب كل( GPAويتم نقاط ضرب حاصل مجموع أساس على

للمقررات المعتمدة الساعات على مقسوما المعتمدة ساعاته عدد فى مضروبا مقرر( . للطالب التراكمى المعدل حساب يتم كما الدراسى الفصل فى الطالب درسها التى

CGPA )كل فى الطالب عليها حصل التى النقاط ضرب حاصل مجموع أساس علىالمعتمدة الساعات مجموع على مقسوما المعتمدة ساعاته عدد فى مضروبا مقرر

الكلية.من مجموعة أو مادة فى الرسوب حالة أ مقررات الفى الدبلوم أووالماجستير فى

. الدكتوراه فقط المجموعة أو المادة فى اإلعادة الذى يتم الفعلى التقدير حساب ويتمتقدير النجاح عند له فيحسب رسوبة تكرر إذا أما فقط إعادة أول فى عليه يحصل

اى% )60 اى 1.67فقط .(C-نقاط

14

Course specificationsMedical Physiology Course Specification

Program(s) on which the course is given: Medical Doctorate degree in medical

physiology

Major or minor element of program: Major

Department offering the program : Physiology department

Department offering the course: Physiology department

Academic year / Level: 1st ,2nd ,3rd,4th ,5th semesters.

Date of specification approval ………………………………………..

A- Basic InformationTitle: Medical Physiology Code:PHY700Credit Hours: 60 Lecture:6h/week Total:330Tutorial: 0 Practical:3h/week Total:180

CoordinatorDr.Bataa ElKafooryDr. Nehal Mohamed Bahgat Gamil

B - Professional InformationCourse Aims:

15

1- provide the candidate with deep knowledge in human physiology &pathophysiology based on cellular and molecular level.

2- enable the candidate to integrate regulatory mechanisms of different body functions in health & disease.

3- enable the candidate to teach different physiology topics in tutorials and lectures.

4- update candidate knowledge and practical skills

2- Intended Learning Outcomes (ILOs) from the Course:a- Knowledge and understanding By the end of the program the candidate will be able to: a1-describe functions of different body systems and the

mechanisms involved in its regulation at cellular and molecular basis.

a2-Describe how different body functions are integrate to maintain homeostasis. b. Intellectual capabilities: By the end of the program the candidate will be able to: b1- Explain disturbed body functions at cellular & molecular level b2- Think and conclude the outcome of a disturbed body function. b3-Analyze the given information. b4- Argue problems through case study and choose the best from multiple .

c. Professional and practical skills :. By the end of the program the candidate will be able to: c1- carry out advanced experiments in practical physiology

Isolated perfused hearts (rabbit & frog). Recording cardiovascular parameters in animals under various

conditions Pulmonary function tests assessement. Skeletal muscle contraction assessement. Smooth muscle contraction Neuromuscular transmission assessement Autonomic functions in humans EMG & nerve conduction velocity Study of platelet aggregation

c2-use different equipments in physiology department for scientific research. d. General and transferable skills:. By the end of the program the candidate will be able to: d1-communicate with medical students in tutorials and lectures. d2- communicate with staff members in physiology department and other

16

departments in seminars and scientific conferences. d3- present seminars, papers in physiology department and medical conferences.

3- Course contents1- First semester; General applied & theoretical courses )first year courses(.

Title: Module 1 Code : PHY7001a

Credit hours;6 hours Lecture : 6 h/week Total; 90h

Topics No. of hoursL P SDL

I) General Physiology A] Membrane and cellular Physiology 1- Homeostasis and feedback mechanisms 2- Cell membrane )structure, characteristics & channels(. 3- Transport across cell membrane. 4- Cellular organelles. B] Membrane potentials:

1-Resting membrane potentials 2-Action potentials

C] Physical principles of gases exchange D] Genetic control of protein synthesis.

5

II) Nerve and Muscle Physiology٭1- Nerve impulse and its conduction2- Electrical events and their ionic bases of skeletal

muscle contraction3- Neuromuscular transmission and its clinical

disorders4- Molecular mechanism of skeletal muscle

contraction-types of contraction5- Energetics of skeletal muscle6- Functions of skeletal muscle inside the body under

normal and abnormal conditions7- Comparative study of smooth and cardiac muscle

versus the skeletal muscle8- Effects of denervation and regeneration

10

(III) Autonomic Nervous System and Adrenal Medulla:1. General properties of sympathetic & parasympathetic

nervous system Autonomic ganglia.2. Sympathetic and parasympathetic supply to body organs

and its functions.3. Cholinergic receptors )structure, type, function agonists &

antagonists(.4. Adrenergic receptors )structure, types, function agonists

and antagonists(.

10

17

5. Synaptic transmission in autonomic nervous system6. Mechanisms of action of autonomic nervous system7. Evaluation of autonomic functions. Autonomic

overactivity and insufficiency. Sympathectomy.8. Autonomic reflexes.9. Autonomic tones and the effects of their failure.10. Higher control of A.N.S.11. Autonomic dysfunction.12. Physiology of adrenal medulla

IV) Blood Physiology1- Plasma proteins: types, origins, concentrations and

their functions. Hypoproteinemia2- Physiology of red blood cells3- Normal and abnormal hemoglobins4- Erythropoiesis, anemia and polycythemia5- Blood groups and blood transfusion6- Haemostasis, coagulation, fibrinolysis and

anticlotting mechanisms. Common coagulation disorders

7- Platelet physiology. Platelet disorders8- Physiology of leucocytes. Leucopoiesis9- Immune mechanisms, allergy, anaphylaxis &

autoimmune disorders10- Physiology of tissue macrophage system 11-Phsiology of lymph12-Body water and water balance

15

V) Cardiovascular Physiology1. Functional structure of cardiovascular system. Heart

as a pump- Haemodynamics- Arterial blood volume and pressure.

2. Electrophsiology of the heart. Electrocardiography- cardiac rate, rhythms and conduction disturbances.

3. Mechanics of the cardiac muscle. Cardiac and systemic function curves

4. Cardiovascular reserve mechanisms and physiology of heart failure- ischemic heart disease

5. Cardiac output and its measurement6. Arterial blood pressure. Hypo. & hypertension.7. Venous circulation and chronic venous insufficiency8. Microcirculation & tissue fluid formation and

oedema9. Physiology of coronary and cerebral circulation10. Portal circulation in the body and their physiological

significance11. Blood flow, resistance, elastance and compliance of

vascular system regional blood flow12. Haemorrhage and shock

40

18

13. Cardiovascular control mechanisms )control of blood volume and control of arterial pressure(

14. Assessment of cardiovascular functions- valsalva’s manoeuvre

15. Lymphatic circulation16. Pulmonary circulation17. Shunt physiology- congenital heart disease

physiologyVI) Respiratory Physiology

1- Functional structure & functional divisions2- Mechanics of breathing )inspiration and expiration(3- Pressure- volume relationships4- Compliance and elastance- resistance5- The work of breathing6- Lung volumes and capacities7- Pulmonary surfactant physiology8- Gas exchange )alveolar ventilation, diffusion &

perfusion(9- Gases transport )O2 and CO2(10- Ventillation perfusion ratio )V/P ratio( and its

mismatching. Physiology of lung diseases11- Pulmonary function tests12- Control of respiration: Nervous, chemical & non

chemical regulation of respiratory center activity13- Physiology of respiratory failure14- Hypoxia circulation15- Dyspnea, orthopnea- artificial respiration16- Decompression sickness17- Respiratory adjustments to high altitude, diving18- Non respiratory functions of the lung19- Anesthesia and postoperative hypoxia. Pulmonary

embolism pneumonectomy

10

XIV)Physiology of Skin1. Functions of the skin. Physiology of itching2. Skin circulation- Dermographism3. Physiology of pigmentation4. Physiology of eccrine and aporine sweat glands5. Physiology of sebaceous gland6. Physiology of hair- hair cycle

*

XV)Physiology of Muscular Exercise1. Changes in skeletal muscle following exercise

training2. Physiological adjustments during various types of

exercise3. Cardiovascular responses to exercise4. Respiratory responses to exercise

*

19

5. Haematological responses to exercise6. Changes in body fluids and electrolytes in response

to exercise7. Endocrinal changes in response to exercise8. Metabolic responses to exercise

L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning.

2- Second semester; General applied & theoretical courses )second year courses(.

Title: Module 2 Code :PHY7001b

Credit hours:6 hours Lecture;8 h/week Total; 90h Topics No. of hours

L P SDL

VII) Renal Physiology1-Functional structure and functions of the kidney2-Body buffer systems3-Kidney functions in the regulation of body fluids. Role

of antidiuretic hormone in the regulation of total body water. Electrolyte balance and their disorders

4-Renal circulation and renal blood flow5-Glomerular filtration and autoregulation6-Plasma clearance7-Renal tubular function )reabsorption and secretion(8- Renal handling of Na+, glucose, bicarbonate and NH3

9- Regulation of excretion of Na+, Cl- and K+

10-Acid-base balance and its disturbance. Anion gap11-Concentration, dilution & acidification of urine12-Physiology of micturition and its disorders13-Physiology of dialysis and renal failure14-Renal function tests

10

VIII) Gastrointestinal Physiology1- Functional structure of the gastrointestinal tract2- Gastrointestinal hormones3- Phsiology of the stomach )gastric digestion &

absorption(. Postgastrectomy syndromes4- Physiology of duodenum & effects of duodenectomy5- Gastrointestinal motility. The vagus and vagotomy.6- Secretory functions of gastrointestinal tract7- Physiology of the colon8- Physiology of gall bladder9- Physiology of pancreas and effects of pancreatectomy10- Physiology of the liver- Jaundice and hepatic failure11- Control of gastrointestinal activities12- Small intestine, absorption and malabsorption13- Gastrointestinal function tests

10

20

XIII) Energy &General metabolism & Body Temperature Regulation

1. Metabolic rate and basal metabolic & specific dynamic action

2. Respiratory quotient )R. Q.( 3. Energy balance, control of food intake, obesity, under &

malnutrition4. Starvation5. Thermoregulatio, hypo & hyperthermia

Metabolic hormone

5

IX) Physiology of Central Nervous System1- Coding of sensory information2- Sensations and sensory lesions3- Motor systems and their lesions. )Muscle tone-

voluntary movements(. Sensory motor relationship4- Physiology of pain and its control5- Reflexes6- Physiology of the neocortex7- Synaptic transmission8- Central neurotransmitters9- Electrophysiology of the brain, Electroencephalogram,

reticular activating system, consciousness, sleep and coma.

10- Hypothalamus. Limbic system11- Interrelation between hypothalamus and limbic system12- Speech & its disorders13- Memory, learning, emotions and motivation14- Physiology of cerebrospinal fluid15- Physiology of association areas and effects of its lesions16- Inhibitory mechanisms in the CNS and theie

physiological significance17- Behavior- criteria for brain death- Decerebration.

Decortication18- Blood brain barrier and cerebral blood flow

40

X) Special Senses Physiology A) Physiology of Vision

1- Functional structure of the eye2- Protective mechanisms of the eye3- Pupillary size and its control4- Optics of vision: Refraction of light and image

formation of the retina- Errors of refraction5- Physiology of the retina: Receptors )types, characters

and mechanisms of stimulation( electroretinogram. Visual acuity

6- Visual pathway & lesions. Visual field and its defects7- Binocular vision

10

21

8- Colour vision and colour blindnessB) Physiology of Hearing

1- Functional structure of ear. Tympanic reflex2- Physiological aspects of sound stimulus3- Auditory receptors and mechanism of hearing4- Auditory pathway. Deafness5- Localization of source and direction of sound

C) Physiology of Smell Olfactory receptors and pathway of olfactionD) Physiology of Taste Gustatory receptors and taste pathwayXII) Endocrine Physiology

1- General concepts in endocrine physiology2- Mechanism of hormonal action3- Hormonal control systems4- Hypothalamic pituitary axis and its physiological

significance5- Pitutary gland and its disorders6- Thyroid gland and its disorders 7- Physiology of adrenal cortex and its disorders8- Glucose homeostasis and pancreas9- Calcium homeostasis and physiology of bone. Tetany10- Physiology of thymus gland11- Physiology of pineal gland12- Physiology of growth13- Puberty14- Interaction between endocrine system and nervous

system15- Hormonal control of sodium, potassium and water

balance- Magnesium balance- phosphorus balance16- Ectopic hormones and autocoids

10

XII) Physiology of ReproductionA) Male Reproductive System

1. Testicular functions2. Testosterone 3. Sertoli cells4. Spermatogenesis & factors affecting it5. Male infertility- Gynecomastia

B) Female Reproductive System1. Female reproductive cycles2. Female sex hormones )estrogen and progesterone(3. Physiology of pregnancy, parturition and lactation4. Placenta and feto-placental unit5. Menopause6. Birth control.

5

22

3- Third semester; Advanced & specialized theoretical courses. Title: Module 3 Code : PHY7002a

Credit hours :6 hours Tutorial:10 h/week Total; 90 h Topics No. of hours

T P SDL (I) ADVANCES IN CELLULAR PHYSIOLOGY:

1- Cell membrane.2- Channels in physiology and ion channel disorders.3- Second messenger pathways.

10

(II)RECEPTORS IN PHYSIOLOGY. 5(III)PHYSIOLOGY OF AGING. 5(IV)ADVANCES IN AUTONOMIC NERVOUS SYSTEM PHYSIOLOGY .

5

(V)PHYSIOLOGY OF STRESS . 5(VI) CYBERNTICS IN PHYSIOLOGY. * (VII) ADVANCES IN CARDIOVASCULAR PHYSIOLOGY :

1- Physiology of vascular endothelial cells nitric oxide and endothelins

2- Relation ship between blood pressure plasma lipids and blood coagulation.

3- Physiology of heart failure. 4- Endocrinal function of the heart. 5- Physiology of congenital heart diseases. 6- Arterial blood pressure etiology control and

management. 7- Physiological approach to mechanisms of

hypertension

35

(VIII) ADVANCES IN BLOOD PHYSIOLOGY: 1- Haemostasis and anticlotting mechanisms. 2- Haematopoiesis and platelet physiology.3- WBCs physiology and immune mechanisms

5

) IX) ADVANCES IN GASTROINTESTINAL PHYSIOLOGY: 1- Intestinal fluid and electrolyte management. 2- G.I.T. neurotransmitters and GIT hormones. 3- Physiology of colon.4- Physiology of diarrhea.

10

(X)ADVANCES IN RESPIRATORY PHYSIOLOGY:1-Endocrine functions of the lung.2- Physiology of respiratory failure.

3- Physiology of bronchial asthma.

5

23

(XI) ADVANCES IN RENAL PHYSIOLOGY:1- Endocrinal functions of the kidney. 2- Physiology of renal failure. 3- Acid – base regulation.

5

L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning

4.Fourth semester; -Advanced & specialized theoretical courses. -Elective course.

Title: Module 4 Code : PHY7002b

PHY7005 or PHY7006 or PHY7007 or PHY7008 Credit hours :6 hours Tutorial:8 h/week Total; 90 h

Topics No. of hoursT P SDL

(XII) ADVANCES IN CENTRAL NERVOUS SYSTEM PHYSIOLOGY: 1-Central neurotransmitters. 2- Physiology of glial cells.3- Glutamine and transporter protein .glutamate receptors –glutamate toxicity .4- Psychiatric and cognitive disorders in disturbed central nervous system physiology. 5- New strategies in CNS regeneration . Neutropins. 6- Recent advances in pathophysiology of spinal cord lesions.7- Physiology of pain and its control. 8- Current concepts on the control of posture and movement.9-Recent advances in learning and memory.

45

XIII) ADVANCES IN ENDOCRINE PHYSIOLOGY: 1- Regulation of growth . Growth factors. 2-Physiology of diabetes mellitus.3- Physiology of osteoporosis. 4- Physiology of prostaglandins.

5- Calcium binding proteins and calcium in health and disease

5

(XIIII) ENVIROMENTAL PHYSIOLOGY: 1- Physiology of diving & space. 2- Physiology of high altitude. 3- Physiological effects of natural antioxidants.

5

(XV) BIOLOGICAL EFFECTS OF ELECTRO MAGNETIC FIELDS: Mechanisms, modeling, biological effects, therapeutic effects, international standards and exposure criteria.

5

(XV) RECENT ADVANCES IN HEALTH AND NUTRITION .

*

24


5- Fifth semester; Practical courses & experimental models. Title: Module 5 Code : ------- Credit hours;6 hours Practical;12h/week Total;180h

TopicsP SDL

(1) Experiments on Nerve and Muscle: Gradation of muscle contraction. The phenomenon of fatigue. Simple muscle twitch. Effect of temperature on simple muscle twitch. Effect of fatigue on simple muscle twitch. Effect of two successive stimuli. Effect of several successive stimuli. Effect of temperature on clonus and tetanus. Effect of fatigue on clonus. Effect of loading on skeletal muscles performances. Nerve conduction velocity–Median nerve conduction

velocity.(2) Experiments on Frog's Heart and Rat Heart:

Determination of the pace maker of heart. Conduction of impulses in the frog's heart.

)Partial and complete heart block(. Refractory period of heart )extra systole(. All or none law in cardiac muscle. A-V interval. Effect of autonomic drugs and ions on heart. Isolated heart perfusion )In vitro studies on rat heart(.

(3) Smooth Muscle and Autonomic Receptors: Rabbit's intestine. Uterine muscle. Adrenergic and cholinergic effects on iris.

(4) Blood Physiology: Determination of hemoglobin content. Determination of packed cell volume )Haematocrit value(-

Anemia – Polycythemia – Blood indices. Erythrocyte sedimentation rate )ESR(. Osmotic fragility test. Evaluation of hemostatic function of blood:

a. Determination of the bleeding time.b. Determination of whole blood clotting time.c. Determination of prothrombin time )PT(.d.Determination of activated partial thromboplastin time )APTT(. - )Purpura–Haemophilia–Hypoprothrombinemia-Hypofibrinogenemia – Hypercoagulability states).

Blood groups:a. ABO.b. Rh.

10

10

10

20

25

(5) Human Cardiovascular Function: Auscultation of heart sounds. Examination of arterial pulse. Jugular venous pulse. Electrocardiogram )ECG(. Measurement of blood flow. Experimental study of microcirculation. Capillary fragility test. Direct observation of capillaries. Vascular responses of the skin.

(6) Respiration: Determination of lung volumes and capacities. Recording of respiratory movements. Measurement and analysis of forced expiration.

(7) Examinations of Sensaions: (A) Examination of Spinothalamic Sensations:

Crude touch sensation. Temperature sensations : cold and Pain sensation:

a. Examination for cutaneous pain.b. Examination for muscle pain – ischaemic pain.

(B) Examination of Dorsal Column Sensations:

Tactile localization. Tactile discrimination. Texture of materials. Kinesthetic sensation: test for:

o Sense of position.o Sense of movement.o Muscle sense.

Vibration sense. Stereognosis. Deep pressure sense. Test for sensory ataxia.

C) Examination for Sensations in the Face.(8) Examination of Motor System.

Nutrition of the muscle. Muscle tone & muscle power.( spasticity & Rigidity) Superficial reflexes (planter, Abdominal, cremastric) Deep reflexes (Tendon jerks): Muscle spindle reflexes.

o In the upper limbs: Biceps and triceps & supinator.

o In lower limbs: knee and ankle jerks. Tests for coordination of movements:

(I) In the upper limbs: 1- Finger - to - nose test.

2- Finger- to - finger test. 3- Pronation and supination test. 4- Overshooting and checkinq tests:

a. Arm pulling tests. b. Wrist slapping test.

30

15

20

40

26

(II) In the lower limbs: 1- Gait. 2- Heel- to - knee test.

Differentiation between sensory and motor ataxia. (III) Fixation Test: Test for Nystagmus.

Motor functions of cranial nerve:1- Examination of cranial nerves III - IV - VI.

(Examine eye movements).2- Examination of cranial nerve V: a.conjunctival rflex

b. Jaw jerk.c. Test for muscles of mastication (clench the teeth).

3- Examination of cranial nerve VII: a. Orbicularis occuli test & corrugator muscle contraction.

(Facial Expression)b. Whistling (Buccinator test)

Muscle (lower face) c.Smilling

4- Examination of cranial nerve X : By movements of soft palate upwards and voice change.

5- Examination of cranial nerve XI :Testing the strength of the trapezius and sternomastoid.

6- Examination of cranial nerve. (By tongue movement). To examine tongue muscles. ·

Differentiation between Upper and lower motor neuron lesions.

Study of Reflexes in Frogs

(9)Special Senses: (A) Physiology of Vision:

1- Estimation of the field of vision: a. Confrontation test. b. Perimetry.

2- Detection of blind spot 3- Pupillarv reactions:

a . Pupillary light reflex and its pathway. b. Accomodation reflex and its pathway.

· Argyl Robertson's pupil. 4- Examination for ey fundus: Ophthalmoscopic examination.

5- Esimation of the visual acuity: (Landolt's and Snellen's charts).

6- Test for colour vision:a. Colored wool test.b. Ischihara book (charts).

B) Examination for Hearing :

15

27

Tests for hearing:a. The watch test.b. Rinne test and comparative Rinne test.c. Weber test.d. Sound localization.e. Audiometry.

10) Practical Metabolism:· Indirect calorimetry: For determination of basal metabolic rate. · Estimation of body fat. 10L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning 4 – Teaching and Learning Methods 4.1-Practical lessons

4.2-Discussion sessions4.3-Research assignment4.4-Candidate presentations.4.5-Self directed learning.4.6-E-learning.

5- Student Assessment Methods5.1 Written Exam. to assess:Knowledge & understanding and intellectual skills.5.2 Practical Exam to assess: Professional& practical skills 5.3 Oral Exam to assess|:General & transferable skills5.4 Thesis to assess: Knowledge, understanding and Intellectual skills, Professional& practical skills and General & transferable skillsWeighing of assessement %End semester 400 21written exam 900 47.5practical exam 450 23.5oral exam 150 8Total 1900 100%

6 -- List of References6.1- Course Notes: Lecturer notes6.2- Essential Books (Text Books) o Review of medical physiology By: William F. Ganong o Text Book of medical physiology By: Guyton.o BEST AND TAYLOR ’ s Physiological basis of Medical practice.

6.3- Recommended Books:o Human physiology from cell to system By: Lauralee Sherwood.

28

6.4- Periodicals, Web Sites, … etco www. Pubmed.com.o Ain Shams medical journalo Am. J. of physiology.o http:// mic2.shams.eg ( Faculty web site)

7- Facilities required for teaching and learning. Computes, library, labs, simulators.

8- Elective Courses Cardiac electrophysiology Platelet physiology Physiology of obesity & adipose tissue Physiology of aviation Advanced pulmonary function tests & respiratory failure. Brain role in body homeostasis

Course specification of cardiac electrophysiologyUniversity: Ain Shams University Faculty: of MedicineCourse specificationsProgram on which the course is given: Medical doctorate in Medical physiologyMajor or minor element of programs: MinorDepartment offering the program: Physiology department Department offering the course: Physiology department. Academic Level: Medical Doctorate in medical physiology– 5th semester Date of specification approval: …………………………..

A- Basic InformationTitle: Cardiac electrophysiology Code: E7003Credit Hours:2 hour Lecture: 2h/week Total: 30 hour

CoordinatorDr.Bataa M. ElKafouryDr. Nehal M.Bahgat Gamil

B - Professional Information1- Course Aims:

provide the candidate with thorough knowledge about electrophysiology of the heart under normal conditions.

29

promote wider understanding of electric changes of the heart under abnormal conditions .

enable the candidate to argue and discuss cardiac electrophysiology & pathophysiology in physiology lectures and tutorials.

enable the candidate to identify updated research points in cardiac electrophysiology.

enable the candidate to read and interpret scientific papers.

2 – Intended Learning Outcomes of Course (ILOs): a- Knowledge and Understanding: By the end of the course the candidate will be able to: a1- describe electrocardiogram and origin of different ECG waves. a2- list disorders of cardiac rhythm and heart muscle damage.

a3- describe electrocardiographic changes under abnormal conditions.

b- Intellectual Skills By the end of the course the candidate will be able to: b1- relate normal physiological principles to the pathogenesis of electric disorders of the heart.

b2- predict the outcome of disturbed electrophysiology of the heart.

c- Professional and Practical Skills By the end of the course the candidate will be able to: c1-explain and illustrate cardiac electrocardiography in physiology lectures. c2-dehtify updated research points in cardiac electrophysiology c3-read and evaluate scientific literature in cardiac electrophysiology

d- General and Transferable Skills By the end of the course the candidate will be able to:

d1 - Work effectively in a group during preparation of seminars. d2- communicate with staff members in the department

d3- Computer skills.

3- Course content:Topic No. of hours

L T SDLOrigin & spread of cardiac excitation

Anatomic consideration Properties of cardiac muscle Pacemaker potentials

122

30

Spread of cardiac excitation 2The electrocardiogram

Bipolar leads. Unipolar leads. Normal ECG. Bipolar limb leads & cardiac vector-

vectorcardiography. Hiss bundle electrogram- monitoring

1221

1Cardiac arrthymias Normal cardiac rate. Abnormal pacemakers, implanted pacemakers,

ectopic foci of excitation- reentry. Atrial arrthymias- ventricular arrthymias-

accelerated AV conduction- antiarrthymic drugs

14

5Electrocardiographic findings in other cardiac & systemic diseases Myocardial infarction. Effects of changes in the ionic composition of

blood.

42

**


4 – Teaching and Learning Methods: Lectures self directed learning Research assignment Candidate presentations

5 - Student Assessment Methods 5.1written exam to assess knowledge and understanding5-2-Weighing of assessment

%Written exam 100 100%

Total 100 100%

6- List of References6.1- Course Notes (paper and / or electronic) Lecture notes.6.2- Essential Books (Text Books)

o Review of medical physiology By: William F. Ganong o Text Book of medical physiology By: Guyton.o BEST AND TAYLOR ’ s Physiological basis of Medical practice.

6.3- Recommended books.

31

Clinical electrocrdiography - a simplified approach. ByAry L. Goldburger6.4- Periodicals, Web sites, … etc

o www. Pubmed.com.o Ain Shams medical journalo Am. J. of physiology.o http:// mic2.shams.eg ( Faculty web site)

7- Facilities required for teaching and learning. ECG device, Computer, skill labs, simulators.

Course specification of Platelet physiology University: Ain Shams University Faculty: of MedicineCourse specificationsProgram on which the course is given: Medical doctorate in Medical physiologyMajor or minor element of programs: MinorDepartment offering the program: Physiology department Department offering the course: Physiology department. Academic Level: Medical Doctorate in medical physiology– 5th semester Date of specification approval: …………………………..

A- Basic InformationTitle: Platelet physiology Code: E7004Credit Hours:2 hour Lecture: 2h/week Total: 30 hour



provide the candidate with thorough knowledge about physiological role of platelets in hemostasis.

promote wider understanding of platelet dysfunction. enable the candidate to argue and discuss platelet physiology &

pathophysiology in physiology lectures and tutorials.

32

enable the candidate to identify updated research points in platelet physiology.


2 – Intended Learning Outcomes of Course (ILOs): a- Knowledge and Understanding: By the end of the course the candidate will be able to: a1- describe platelet biochemistry and its role in hemostasis

a2- list disorders of platelet & hemstasis. a3- list platelet function tests

b- Intellectual Skills By the end of the course the candidate will be able to: b1- relate normal physiological principles to the pathogenesis of platelet dysfunction and hemostatic disorders.

b2- predict the outcome of platelet dysfunction. b3-use the basis of platelet physiology in interpreting platelet function tests.

c- Professional and Practical Skills By the end of the course the candidate will be able to: c1-discuss and explain platelet physiology in physiology lectures& tutorials c2-idehtify updated research points in platelet physiology & pathophysiology. c3-read and evaluate scientific literature in platelet physiology



3- Course content :

Topic No. of hoursL T SDL

introduction 2Platelet biochemistry- platelet production and structure 4

Role of platelets in hemostasis 10Platelet disorders

Types Clinical features

10

Tests of platelet function 4 *

33



5 - Student Assessment Methods5.1written exam to assess knowledge and understanding5-2-Weighing of assessment


Total 100 100%



6.3- Recommended books. Hematology for the medical students.By; Alvin H. Schmaier,Lilli M . Petruzzelli6.4- Periodicals, Web sites, … etc

o www. Pubmed.com.o Ain Shams medical journalo Am. J. of physiology.o http:// mic2.shams.eg ( Faculty web site)

7- Facilities required for teaching and learning. Computer,skill labs, simulators

34

Course specification of Physiology of obesity & adipose tissue

University: Ain Shams University Faculty: of MedicineCourse specificationsProgram on which the course is given: Medical doctorate in Medical physiologyMajor or minor element of programs: MinorDepartment offering the program: Physiology department Department offering the course: Physiology department. Academic Level: Medical Doctorate in medical physiology– 5th semester Date of specification approval: …………………………..

A- Basic InformationTitle: Physiology of obesity & adipose tissue Code: E7005 Credit Hours:2 hour Lecture: 2h/week Total: 30 hour



provide the candidate with thorough knowledge about physiological role of adipose tissue.

promote wider understanding of adipose tissue dysfunction and its

35

relation to diseases and obesity. enable the candidate to argue and discuss adipose tissue physiology &

pathophysiology in physiology lectures and tutorials. enable the candidate to identify updated research points in adipose tissue

physiology & obesity. enable the candidate to read and interpret scientific papers.

2 – Intended Learning Outcomes of Course (ILOs): a- Knowledge and Understanding: By the end of the course the candidate will be able to: a1- describe adipose tissue structure & function

a2- understand the the relationship between adipose tissue dysfunction and some diseases. a3- identify the etiology of obesity and its impact on theheart. a4-understand regulation of food intake and energy balance. a5- identify experimental models of obesity.

b- Intellectual Skills By the end of the course the candidate will be able to: b1- relate basis of adipose tissue physiology to the pathogenesis of insulin resistance , cancer and fatty liver.

b2- predict the outcome disturbed energy balance and obesity.

c- Professional and Practical Skills By the end of the course the candidate will be able to: c1-discuss and explain adipose tissue physiology, energy balance and obesity in physiology lectures& tutorials. c2-idehtify updated research points in adipose tissue physiology & obesity. c3-read and evaluate scientific literature in cardiac electrophysiology


d1 - Work effectively in a group during preparation of seminars. d2- communicate with staff members in the department.


L T SDLAdipose tissue structure & function

The adipose organs Metabolism of white adipose tissue

4

36

Leptin Adiponectin

Vasoactive factors & inflammatory mediators produced by adipose tissue.

4

Adipose tissue & disease Insulin resistance Fatty liver Cancer

4

Genetics of human obesityFetal origin of obesity

4 *

Diet composition and the control of food intake in humans.

4 *

Central integration of peripheral signals in the regulation of food intake and energy balance- role of leptin & insulin

6

Experimental models of obesity 4

Obesity & the heart 2 L: Lecture, T: Tutorial, C/P: Clinical or Practical and SDL: Self directed learning4 – Teaching and Learning Methods: Lectures self directed learning Research assignment Candidate presentations



Total 100 100%6- List of References6.1- Course Notes (paper and / or electronic) Lecture notes.6.2- Essential Books (Text Books)


6.3- Recommended books.

37

o Adipose tissue &adipokines in health & disease. By; Giamila Fantuzzi,Theodore Mazzone.

o Handbook of obesity:etiology & pathophysiology.By; George A. Bray,Claude Bouchard.

6.4- Periodicals, Web sites, … etco www. Pubmed.com.o Ain Shams medical journalo Am. J. of physiology.o http:// mic2.shams.eg ( Faculty web site)

7- Facilities required for teaching and learning. Computer,skill labs, simulators

Course specification of Physiology of aviation and space University: Ain Shams University Faculty: of MedicineCourse specificationsProgram on which the course is given: Medical doctorate in Medical physiologyMajor or minor element of programs: MinorDepartment offering the program: Physiology department Department offering the course: Physiology department. Academic Level: Medical Doctorate in medical physiology– 5th semester Date of specification approval: …………………………..

A- Basic InformationTitle: Physiology of aviation & space Code: E7006Credit Hours:2 hour Lecture: 2h/week Total: 30 hour



provide the candidate with core knowledge about physiologof aviation and space.

promote wider understanding of physiological changes during aviation, acceleration,exposure to microgravity and decompression sickness.

enable the candidate to argue and discuss issues of aviation & space physiology in physiology lectures and tutorials.

enable the candidate to identify updated research points in aviation &

38

apace physiology. enable the candidate to read and interpret scientific papers.

2 – Intended Learning Outcomes of Course (ILOs): a- Knowledge and Understanding: By the end of the course the candidate will be able to: a1- describe oxygen handling in altitudes.

a2- identify decompression sickness. a3-understand physiological changes during acceleration and on exposure to hypogravic environment. a4-list aviation –related disorders.

b- Intellectual Skills By the end of the course the candidate will be able to: b1- relate basis of normal physiology to the physiological changes that occur during aviation, acceleration and exposure to hypogravic environment. b2- predict the outcome of disturbed body physiology during aviation, acceleration and exposure to hypogravic environment. . c- Professional and Practical Skills By the end of the course the candidate will be able to: c1-discuss and explain aviation physiology and related issues in physiology lectures& tutorials. c2-identify updated research points in aviation physiology and related issues c3-read and evaluate scientific literature in aviation physiology d- General and Transferable Skills By the end of the course the candidate will be able to:



L T SDLPhysiology of altitudes 1Oxygen handling in altitudes

Altitude )hypobaric hypoxia(. Hyperventilation Hyperbaric oxygen therapy-oxygen toxicity

316

39

Decompression sickness 5Acceleration)+G2, -G2(.

7

Hypogravic )Microgravic (physiology 1Spatial orientation & disorientation 3Aviation related loss of consciousness 1Visual problems of orientation 2





Total 100 100%



6.3- Recommended books.o Human performance and limitations in aviation. By; R. D.

Campbell,Michael Bagshaw.o Basic flight physiology.By; Richard O. Reinhart


7- Facilities required for teaching and learning.

40

Computer,skill labs, simulators

Course specification of advanced respiratory function tests & respiratory failure

University: Ain Shams University Faculty: of MedicineCourse specificationsProgram on which the course is given: Medical doctorate in Medical physiologyMajor or minor element of programs: MinorDepartment offering the program: Physiology department Department offering the course: Physiology department. Academic Level: Medical Doctorate in medical physiology– 5th semester Date of specification approval: …………………………..

A- Basic InformationTitle: Advanced respiratory function tests & respiratory failure Code: E7007Credit Hours:2 hour Lecture: 2h/week Total: 30 hour

CoordinatorDr.Bataa M. ElKafouryDr. Nehal M.Bahgat GamilB - Professional Information1- Course Aims:

provide the candidate with thorough knowledge about physiological basis of respiratory function tests and respiratory failure.

promote wider understanding of respiratory function tests and respiratory failure.

41

enable the candidate to argue and discuss respiratory function tests and respiratory failure in physiology lectures and tutorials.

enable the candidate to identify updated research points in respiratory physiology.

enable the candidate to read and interpret scientific papers.2 – Intended Learning Outcomes of Course (ILOs): a- Knowledge and Understanding: By the end of the course the candidate will be able to: a1- list pulmonary function tests.

a2- understand physiological basis of different pulmonary function tests. a3-understand pathophysiology of respiratory failure

b- Intellectual Skills By the end of the course the candidate will be able to: b1- relate basis of pulmonary physiology to pulmonary function tests. b2- use basis of pulmonary physiology to explain pathophysiology of respiratory failure.

c- Professional and Practical Skills By the end of the course the candidate will be able to: c1-discuss and explain pulmonary function tests in physiology lectures& tutorials. c2-identify updated research points in pulmonary physiology. c3-read and evaluate scientific literature in aviation physiology d- General and Transferable Skills By the end of the course the candidate will be able to:

d1 - Work effectively in a group during preparation of seminars. d2- communicate with staff members in the department.d3-computer skills.


L T SDL lung volume Tests

Vital capacity )VC(, Inspiratory capacity )IC( &expiratory reserve volume ) ERV(.

Functional residual capacity )FRC(& residual volume )RV(.

Thoracic gas volume )VTG(. Total lung capacity )TLC( & residual

7

42

volume/total lung capacity ratio ) RV/TLC X 100 (.

Ventilatory control tests; Tidal volume )VT(. Minute ventilation )VE(. Respiratory dead space )VD(. Alveolar ventilation)VA(.

5

Pulmonary mechanics; Forced viatl capacity Forced expiratory volume / Forced vital

capacity ratio)FEVT /FVC(. Forced expiratory flo 25%-75% )FEF25%-75%(. Peak expiratory flow )PEF( Flow volume curves Maximum voluntary ventilation )MVV(. Airway resistance & airway conductance

)Raw( & )Gaw(. Specific conductance )SGaw(. Maximl inspiratory pressure & maximal

expiratory pressure ) MIP( & )MEP(

7

Overview of exercise testing 2Anerobic threshold 2Applied respiratory muscle physiology 3Respiratory failure

Disorders of control of ventilation Specific neuromuscular disorders

4





Total 100 100%

43



6.3- Recommended books.o Pulmonary physiology. By:Michael G. Levitzky.o Principles of cardiopulmonary exercise testing & its interpretation. By:

Prof. Dr. Mohamed El-Batanouny & his colleagues. Cairo university, Faculty of medicine, Fitness & Rehabilitation unit.

o Current medical diagnosis & treatment. By; Stephen J. McPhee,Lawrence M. Tierney,Maxine A. Papadakis

o Prcatical pulmonary &critical care medicine:disease management. By: Zab Mohsenifar,Guy W. Soo Hoo.


7- Facilities required for teaching and learning. Computers, skill labs, simulators.

44

Course specification of brain role in body homeostasisUniversity: Ain Shams University Faculty: of MedicineCourse specificationsProgram on which the course is given: Medical doctorate in Medical physiologyMajor or minor element of programs: MinorDepartment offering the program: Physiology department Department offering the course: Physiology department. Academic Level: Medical Doctorate in medical physiology– 5th semester Date of specification approval: …………………………..

A- Basic InformationTitle: Brain role in body homeostasis Code: E7008Credit Hours:2 hour Lecture: 2h/week Total: 30 hour



provide the candidate with thorough knowledge about brain role in body homeostasis.

promote wider understanding of respiratory function tests and respiratory failure.

enable the candidate to argue and discuss physiological role of the brain in homeostasis in physiology lectures and tutorials.

45

enable the candidate to identify updated research points in neuro-physiology and neuroendocrinology.


2 – Intended Learning Outcomes of Course (ILOs): a- Knowledge and Understanding: By the end of the course the candidate will be able to: a1- understand the concept of body homeostasis and brain role in its maintenance.

a2- describe the homeostatic mechanisms involved in maintenance of various metabolic parameters of the body.

b- Intellectual Skills By the end of the course the candidate will be able to: b1- interprete various homeostatic mechanisms of the body. b2- predict the impact of disturbed brain function on body homeostasis.

c- Professional and Practical Skills By the end of the course the candidate will be able to: c1-discuss and explain physiological role of the brain in homeostasis in physiology lectures& tutorials. c2-identify updated research points in neurophysiology &neuroendocrinology. c3-read and evaluate scientific literature in neurophysiology and neuroendocrinology. d- General and Transferable Skills By the end of the course the candidate will be able to:

d1 - Work effectively in a group during preparation of seminars. d2- communicate with staff members in the department.


L T SDLHypothalamic integration of energy metabolism.The TRH neuron; a hypothalamic integrator of energy metabolism.

4

4

46

Hypothalamic integration of blood –borne stimuli.Integration of metabolic stimuli in the arcuate nucleous.

4

4

Hypothalamic integration of immune system 4

Neuroendocrine regulation of water balance 3Circardian timing in health and disease. 1

Organization of circardian function 2The hypothalamic clock and its control of glucose homeostasis.

2

Influence of light and the pineal gland on biological rhythms.

2





Total 100 100%6- List of References6.1- Course Notes (paper and / or electronic) Lecture notes.6.2- Essential Books (Text Books)


6.3- Recommended books.o Hypothalamic integration of energy metabolism; By Andries Kalsbeek.o Neiroendocrinology in physiology an dmedicine. By; P. Michael

Conn,Marc E. Freeman6.4- Periodicals, Web sites, … etc

o www. Pubmed.com.

47

o Ain Shams medical journalo Am. J. of physiology.o http:// mic2.shams.eg ( Faculty web site)

7- Facilities required for teaching and learning. Computer, skill labs, simulators

V- General Information 1 – Monitoring Of Training and Submission Of Training Reports

You must keep proper and updated records in your logbook to reflect the activities encountered in your training. Your logbook must be duly endorsed by an authorized signatory at the end of each semester.

You will be continuously assessed by your supervisors, in consultation with head of department. An assessment will be submitted within 2 weeks of completion of each semester. 2 - Miscellaneous Information:Injury and/or Blood or Body Fluid Exposure:During regular working hours, you should immediately report an exposure incident to Chemicals or toxins. If exposure occurs after regular working hours or during a weekend or holiday; please call the supervisor. 3 - Action Completion Of Clinical Training

Once all training sessions are completed the log book should be signed by the senior supervisor and the head of the department and then should be submitted to post graduate Secretariat. 4- ReferenceThe Training Guide is available at the post graduate Secretariat and could be downloaded from the following website is

---------------------------------------------------------------VI – Your log book

48

1- IntroductionThe aim of this book is to give you a guide to the expectations for each

item. It will be a guide for both you and your teachers to what you should be seeing and doing.

It will give you a list of the important topics that you should think about and should be covered in:

1. Practical sessions or2. Tutorials3. Self-directed learning )SDL(

For each item there is also a list of Practical procedures to be seen and done Professional experiences to be done

RememberThis document is only a guide. It is not an exhaustive list. It is not just a checklist to score points. It is a guide to encourage you to read and learn more. This book is for your benefit. It will form a record of your clinical training and experience.2 – Supervisors:……………………………………………………………………………………...3–Tables for Training RecordsCandidates are required to fulfill 75% of the listed activities in order to be eligible for the exam entry. The minimum number required for each activity = 75%. You are free to attend more and record your extra attendance.

Weekly Department PlanDay /time Saturda

ySunday Monda

y Tuesda

y Wednesday Thursday

Scientific conference

٭ Undergraduate Teaching ٭ ٭ ٭ ٭ ٭ ٭Demonstrationsfor under-graduates

٭

Postgraduate alectures ٭ ٭ ٭Monthly activity; SeminarsYearly activity; Ain shams medical conference

49

Scientific Assignments(NB. Minimum number required is 5 )

No

Dat

e

Plac

eTopics Supervisor

signature

1

2

3

4

5

Teaching experience(NB. Minimum number required is 20)

No

Dat

e

Plac

e

Topics Supervisor signature

123456789

1011121314

50

151617181920

Seminars attendance(NB. Minimum number required is 5 )

No Date Place Topics Supervisor signature

1

2

3

4

5

Presentations(NB. Minimum number required is 5 )

No Date Place Topics Supervisor signature

1

2

3

4

5

51

Thesis attendance(NB. Minimum number required is 10.)

No Date Place Name of the thesis Supervisor signature

1

2

3

4

5

6

7

8

9

10

Conferences attendance(NB. Minimum number required is 2)

No

Dat

e

Plac

e

Topics Supervisor signature

12

Practical skills (Agreement Scale)Requirements

52

Candidates are required to fulfill 75% of the listed activities in order to be eligible for the exam entry. The minimum number required for each activity = 75%. You are free to attend more and record your extra attendance

Item No

Obs

erve

d

Dat

e

Don

e in

depe

nden

tly(A

, B, C

)D

ate

Supe

rvis

or

sign

atur

e

1-Isolated perfused heart

12345

2-Recording of cardiovascular parmeters in animals under various conditions

12345

3-Study of platelet aggregation

12345

4-Pulmonary function tests

12345

5-Neuromuscular transmission assessement

12345

6-Record of intestinal motility

1234

53

5a- Poor b- Satisfactory c- Excellent

5 - Log book previewThe candidate logbook will be reviewed and skills performed

summarized during the semester evaluation and at the end of the course in the table below. This reflects the number of activity done by category. (According to each degree) The results of this review will be totaled in the summary chart below.

SummarySemester 1st 2nd 3rd 4th 5th 6th Total

Activity No No No NoNo No

1-Scientific assignment 1 1 1 1 1 5

3-Teaching experience 4 4 4 4 4 20

4-Seminar attendance 1 11 1

1 5

5-Presentations 1 1 1 1 1 5

6-Thesis attendance 2 22 2

2 10

7-Conference attendance1

1 2

8-Practical skills 1 23& 4

5 66

Supervisor signature

54

VII - Head Of Department Approval For The Exam Entry___________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________

55

_____________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________

56

VIII – Thesis Follow upالتقرير النصف السنوى لعام / التاريخ/

عن الطالب / المقيد لدرجة ( ماجسيتر / الدكتوراة )

بقسم /تقرير السادة االساتذة المشرفين

جم��ع الم��ادة العلمي��ة وكتابة المقدمة

شوطابدأ قطع محدودا

أوش��ك علىاإلنتهاء

إنتهى منالجمع

شوطابدأالجزء العملى قطع محدودا


إنتهى منالتحليل

57

شوطابدأمناقشة النتائج قطع محدودا


إنتهى منالتحرير

المراجع��ة النهائي��ة م��عالمشرف



إنتهت تماما

رأى الس��ادةالمشرفين

إس��تمرار قي��دالطالب

مد القيد

ش��طب قي��د الطالب

تم تش��كيل لجن��ةالمناقشة

نعم ال

ت��اريخالتشكيل

/ /

مد / شطب القيد وكيل الكليةتوقيع السادة المشرفين

58








59













مد القيد



نعم ال


/ /


60




61

















مد القيد



نعم ال


/ /


62

VIII – Thesis Follow up

63

التقرير النصف السنوى لعام / التاريخ/عن الطالب /

المقيد لدرجة ( ماجسيتر / الدكتوراة )بقسم /

تقرير السادة االساتذة المشرفين

















مد القيد



نعم ال


/ /


64




















مد القيد



نعم ال


/ /


66




















مد القيد


68


نعم ال


/ /


69

VIII – Evaluation Forms Evaluation Form (at the end of each semester)To be completed at -------------------------------------Candidate SupervisorLocation

Aim of training ______________________________________________________________________________________________________________________________________________________________________________________________________ Agreed educational objectives and timescale in which objectives should be achieved. ______________________________________________________________________________________________________________________________________________________________________________________________________

Comments by Candidate______________________________________________________________________________________________________________________________________________________________________________________________________

Comments by Supervisor ______________________________________________________________________________________________________________________________________________________________________________________________________

70

__________________________________________________________________

Date of next meeting

Signed by candidate

Signed by Supervisor

Date

71





72

__________________________________________________________________


Signed by candidate


Date

73





74

__________________________________________________________________


Signed by candidate


Date

75





76

__________________________________________________________________


Signed by candidate


Date

77





78

__________________________________________________________________


Signed by candidate


Date

79




Comments by Supervisor ____________________________________________________________________________________________________________________________________

80

____________________________________________________________________________________________________________________________________


Signed by candidate


Date

81

Degree Program Evaluation Form by The CandidateTo be completed at the end of your degree.

Please consider each pair of statements and decide which most clearly reflects your view and tick one box or answer the question.

I. Individual Information1. Are you a graduate of ASU?

yes no to some degree2. Year and semester when studies began:

II. General Questions1. What are the advantages/disadvantages of the general study environment at the University ASU?

2. What were your expectations when you applied to the degree?

3. Do you feel that the degree program prepares you well for your future studies or employment according to the demands and expectations of those institutions?

yes no to some degree

82

4. Has the time limit of the program (two or three academic years) caused you any difficulties or inconveniences?


III. Structure of Degree Program1. Did you receive enough guidance in planning your study schedule in the beginning of the program?


2. What were the main difficulties in the planning of your study schedule?

3. What is your general opinion on the structure of the degree program?

4. In your opinion, does the degree program offer a good balance of lectures, seminars, conferences, and book exams?


a) General Studies

i) Do you feel that you have received enough guidance on academic writing?


ii) Do you feel that you have acquired sufficient knowledge on research skills (eg. quantitative and qualitative research methods)?


b) Courses

i) Have you had some special difficulties in completing some of the courses? Please specify.

ii) Has there been a sufficient variety of courses offered for your optional studies?


83

iii) Have you received enough guidance for the preparation of your thesis?


IV. Concluding Points1. Did the degree program meet your expectations?

yes no to some degree2. What aspects of the degree program do you particularly like?

3. What aspects of the degree program do you particularly dislike?

4. What are your suggestions on how to improve the program?

Thank you!

84

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