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MD/PhD Program “Molecular Medicine“
Hannover Biomedical Research School at Hannover Medical School
Report 2006
MD/PhD Program “Molecular Medicine“
Hannover Biomedical Research School (HBRS) at Hannover Medical School
Responsible Univ. Prof. Dr. Reinhold E. Schmidt Chairman MD/PhD Program Carl-Neuberg Str. 1 30625 Hannover Tel: 0511-532-6656 [email protected] MD/PhD committee:
Prof. Dr. A. Gossler, Prof. Dr. H. Drexler, Prof. Dr. C. Baum, Prof. Dr. C. Klein, Prof. Dr. R. Lichtinghagen, Prof. Dr. M. Gaestel, HD Dr. B. Sodeik, PD Dr. T. Tschernig, Dr. E. Jäckel, Dr. E. Hesse/ Prof. Dr. D. Gadzicki, Dr. M. Ünalan, M. Rhein, N. Heinz Dr. Susanne Kruse, Marlies Daniel MD/PhD Office
OE 9117 Carl-Neuberg Str. 1 30625 Hannover Tel. 0511-532-6011 [email protected] [email protected] Internet: www.mh-hannover.de/hbrs.html
Chairman of the MD/PhD program
The MD/PhD program “Molecular Medicine“ was established in autumn 2000. Our program has meanwhile become one of the leading PhD programs in Germany due to excellent interdisciplinary cooperation between the Hannover Medical School (MHH), the University, the School of Veterinary Medicine Hannover and the Helmholtz Center for Infection Research (HZI), Braunschweig, due to the support of the International Promotion Program (IPP) by DAAD and DFG. We are also proud to have international outstanding teachers, such as Prof. Fritz Melchers (Immunology), in our program. It is also the first German PhD program which has been accreditated according to European standards (modules ECTS). There is a good ratio between medical students and students from life sciences as well as between German and foreign students. This program attracts great national and international interest. Additionally, the MD/PhD program is the basis for the Hannover Biomedical Research School (HBRS) founded in 2003, which has been extremely successful in integrating all postgraduate programs at MHH. Joint curricula have been established. We are very proud that the HBRS is now funded (with 5 Million Euro) by the German Excellence Initiative (DFG) for the next five years. Meanwhile, more than fifty students have successfully graduated from the program. They are ambassadors for MHH around the world. Many sponsors are generously providing support for our workshop or stipends for our students. Many thanks to everyone who has supported this MD/PhD program, especially to those students who determine the excellence of the program.
Reinhold E. Schmidt, MD Professor of Medicine and Immunology
Dean of Hannover Biomedical Research School
We express our thanks to our sponsors: “Friends of MHH” Martin Lawrenz, Hannover
Table of Contents
I. Current Status, Problems and Prospects_________________________ 7
1. Current Status _____________________________________________________________________7 2. Common Rules____________________________________________________________________10 3. Cooperation with International Institutes______________________________________________11 4. Success and measures for implementation _____________________________________________12
II. Measures and Results _______________________________________ 13
1. Personnel ________________________________________________________________________13 1.1. Scientific collaborators and administrative personnel _________________________________________ 13 1.2. Tutors ______________________________________________________________________________ 14
2. Language courses _________________________________________________________________14 3. Social Activities ___________________________________________________________________14 4. Organization of Educational Material_________________________________________________15 5. Marketing Measures _______________________________________________________________15 6. Guest Lectures and additional colloquia_______________________________________________16 7. Travel ___________________________________________________________________________17 8. Visits abroad by the graduate students ________________________________________________17
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I. Current Status, Problems and Prospects
1. Current Status
Statistics Applications 2006
Country Number of applicants Now in the program
Total female male total female male
Germany 38 24 14 8 4 4
Western Europe: 7 3 4 2 1 1
Central and Eastern Europe
27 14 13 - - -
North America: - - - - - -
Latin America: 10 7 3 - - -
Africa, Subsahara: 27 9 18 - -
North Africa and Middle East:
30 13 17 1 1 -
Asia, Australia and Oceania:
271 84 187 8 6 2
Total: 410 154 256 19 12 7
Final exams in the MD/PhD program 2006:
16 students did their final exams in June and November 2006. From 17 students of the year 2003, five
did their final exams after exactly 3 years = 30%, six plan to finish after 3.5 years, six after 4 years.
Detailed Description At the moment (February 2007) there are 73 students in the program [36 women and 27 men; 51
international and 22 Germans; 18 medical students (incl. veterinary students) and 55 life scientists].
The international students come from Austria (2), Bolivia (1), China (4), Columbia (1), Estonia (1),
Ethiopia (1), Georgia (1), Hungary (1), India (30), Iran (1), Indonesia (1), Kenia (2), Mongolia (1),
Poland (1), the Netherlands (1), Ukraine (1) and Zimbabwe (1).
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The students are either financed by the corresponding departments or by scholarships (DAAD; MHH,
industry etc.). We are very happy that from 2007, HBRS will provide a number of half stipends
(1.250,-Euro/month for 18 months) for the best ten students of the ranking list after selection.
Concerning selection of the new students, a 3-step level procedure was introduced in 2002. It consists
of: 1. preselection by the PhD commission, 2. a written test in the individual home countries, 3. an
interview (in 2006 in Hannover, New Delhi and Hyderabad, India, and Harbin, China). In 2002 an
extensive application form was developed, which as further improved in 2006. Now, all programs in
the HBRS have adapted this application form.
The selection of the applicants is based on qualification only. The accepted candidates are supposed to
choose a department and a research project themselves. This means that there can be bottle-necks
regarding the guarantee of the financing of the students. For this reason scholarships were successfully
applied for in e.g. the Excellence Initiative of the German government.
In 2006, orientation weeks were organized from October 1st to 16th with the kind support of about
10.000 Euro by the DAAD (Stibet) and “Welcome in Niedersachsen” (WIN).
Students work on a 3-year research project in one of the departments of the MHH or at cooperating
institutes (see list of students). In addition, there is an obligatory program of teaching consisting of
seminars and tutorials (see list of lecturers).
In October 2003, the Graduate School: “Hannover Biomedical Research School” (HBRS) was founded
at MHH (director: Prof. Dr. R.E. Schmidt, office: Dr. S. Kruse). Here, all graduate programns [PhD
(MD/PhD “Molecular Medicine”, PhD “Infection Biology”, new PhD “Regenerative Sciences”,
Graduate Colleges (GRK 705, GRK 1441, European GRKs “Pseudomonas” and “Strategies of human
pathogens to establish acute and chronic infection”), etc.] are coordinated.
In 2004, a joint Curriculum of the HBRS [MD/PhD program, PhD program “Infection Biology”
(speaker: Prof. Dr. Förster) and Miditrain (GBF, EST Marie Curie, speaker: Prof. Dr. Hauser); GRKs]
was established in order to bundle resources.
In the first year, basics and methods of biology and medicine are taught. There are special in-depth
seminars for medical students as well as life scientists.
During the second academic year, focus lies more on current research projects (applied aspects). Since
2003, four main foci have been established in the MD/PhD program: Immunology; Infection;
Oncology and Differentiation; Genetics and Cell Biology (Fig. 2).
Besides an extensive English curriculum, guest seminars, scientific colloquia, discussions with the
supervisors and technical practical courses took place.
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Most important are the so-called “soft skills“ as well as seminars about “Research Ethics” (members of
the institute of “Science and Ethics”, Bonn), “Animal Experiments“ (Prof. Hedrich), “Scientific
Writing“ (Dr. Kruse), “Presentation techniques” (Prof. Dierks), “Intercultural communication”
(together with Göttingen), “Stress Management” (Kümmerle, Berlin), “Career perspectives” etc.
The students keep book about all seminars. The lecturers are regularly evaluated by students.
After 18 months, students give an oral intermediate exam in the respective main subject and the
subject of the co-examiner (presentation and discussion of a research paper). After 3 years the final
exam is given in form of a public disputation.
In 2006, sixteen MD/PhD students (Diya Abraham, Max-Planck Institute, India; Khaled Alkharsah,
Virology, Syria; Georg Bohn, Pediatric Hematology and Oncology, Germany; Tammy Chang,
Pediatrics, Germany; Anuhar Chaturvedi, Hematology and Oncology, India; Shipra Gupta,
Pharmacology, India; Christoph Happel, Pediatric Hematology and Oncology, Germany; Vladimira
Jakubcakova, Max Planck Institute, Slovakia; Shashi Kant, Physiological Chemistry, India; Yijiang Li,
Thoracic and Cardiovascular Surgery, China; Anika Hofmann née Meyerholz, Cell Biology, Germany;
Gesa Meyer, Toxicology, Germany; Rahul Purwar, Dermatology, India; Krishna Kumar Singh, Human
Genetics, India; Manvendra Kumar Singh, Molecular Biology, India; Linding Wang, Virology, China)
successfully finished the program. Next final exams will be on June 15th and November 9th, 2007.
The ECTS System was introduced (credit points = cp; see Fig. 1). The program was accreditated
according to European standards by ZEvA on December 9th, 2003.
Figure 1. Study Structure MD/PhD Program “Molecular Medicine“
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3-year PhD project work (125 cp) Annual presentation in department (3x; 10 cp) Journal club (3x; 3 cp) Public annual presentation/project report (3x; 10 cp) Talk/presentation on international congress (2 cp)
Basics (seminar and tutorial; 3 h per week; 8 cp)
Year 1 Year 2 Year 3
Interdisciplinary seminars/courses (60 h; 6 cp) Project-orientated seminars/courses (80 h; 8 cp)
PHD thesis
and Final exam Complex and clinical
systems (seminar and tutorial; 3 h per week; 8 cp)
Intermediate Exam after 18 months
Figure 2. Curriculum 2006/7
In September 2002, a German-wide network of biomedically orientated PhD programs was established
(currently more than 15 members). Further improvement of the coordination of selection procedures
(exams and interviews) was achieved. In 2006, the third joint workshop on “Intercultural
communication” was organized by the PhD programs of Göttingen and Hannover in Springe (Deister).
2. Common Rules
On 15.12.99, a rule for the MD/PhD program was passed by the senate of Hannover Medical School.
This rule unites a regulations for studies and exams. On 12.02.02, the MD/PhD program received
authorization from the Lower Saxony Ministry for Science and Culture to alternatively award besides
the PhD title for scientists the title Dr. rer. nat. Such changes in the rules and adaption to the program
situation were passed by the senate on 04.06.02. On 11.02.04, the rules were adapted to the
suggestions by the committee of referees for accreditation and were overall updated, same accounts for
April 2005. Currently, the PhD rules are adapted for all programs in the HBRS. In addition, special
rules and regulations for HBRS are developed.
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For all: Seminar, 2h and Tutorial, 1h
1st year
In parallel: special in-depth seminars for medical students and students from life sciences, respectively
Basics in Molecular Medicine (Focus on Methods) Seminar, 2h
Tutorial, 1h
Tutorial for the respective seminar/tutorial series
1st sem. 2nd sem.
2nd year
1. Focus: Immunology
2. Focus: Genetics & Cell Biology
3. Focus: Infection
4. Focus: Differentiation & Oncology
or
or
4th sem.3rd sem.
3rd year: concentration on individual research projects
Immunology/Stem Cell Biology/ Bacteriology/ Virology
Cell Biology/ Genetics/ Biochemistry/ Methods
3. Cooperation with International Institutes
Fortunately, within the MHH there is an active exchange, i.e. participation of almost all scientifically
active departments in the MD/PhD program – whether by means of active organizing within the
MD/PhD commission, by supervising the MD/PhD students at the research laboratories or as lecturers
in the numerous educational programs. This goes for the basic scientific as well as for the clinically
orientated departments, for example: Biochemistry, Cardiology, Cell Biology, Clinical Immunology,
Dermatology, Gastroenterology-Hepatology-Endocrinology, Genetics, Hematology, Heart and
Thoracic Surgery, Immunology, Microbiology, Molecular Biology, Nephrology, Oncology, Pathology,
Physiology, Rheumatology, Tumor Biology, Virology, Visceral and Transplantation Surgery, etc.
Therefore intensive cooperation exists between collaborators (Post-docs etc.) from Graduate Colleges
with the MD/PhD program. Moreover, the “Graduate School” (HBRS) was founded in October 2003.
There is close cooperation between the graduate and PhD programs of the School of Veterinary
Medicine Hannover, also concerning lecturers and students. In addition, there are very close
cooperations to the Helmholtz Center for Infection Biology (HZI) in Braunschweig and the Fraunhofer
Institute for Toxicology and Experimental Medicine (ITEM) in Hannover. Thanks to the scientists of
the MHH there is already intensive cooperation with European and internationally very well-known
research institutes (e.g. also by means of the two European Research Training Groups). Of course, the
PhD students profit from this cooperation, too.
A constant exchange and participation in education and research exists with the following institutes:
a) national:
• Helmholtz Center for Infection Research (HZI); Braunschweig • School of Veterinary Medicine, Hannover • Fraunhofer Institute for “Toxicology and Experimental Medicine” (ITEM), Hannover • Institute for “Animal Breeding”, Mariensee (FAL) • Center for Stem Cell Research, Gatersleben • Max-Planck Institute for Infection Biology Berlin • Leibniz University of Hannover • Technical University of Braunschweig There is intensive cooperation with these national institutes as well as concerning education (lecturers) and concerning research, i.e. making three year projects available or the function of scientists as co-supervisors.
b) international (especially with):
• Centre for DNA Fingerprinting (CDFD), Hyderabad, India With Prof. Dr. S. Hasnain there has been intensive contact since 2002 (see guest lecturer and trip to India). The establishment of a mutual “summer school“ is planned and the exchange of scientists will be realized within the Indo-German Science Center.
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c.) Economy/Industry (especially with):
Solvay GmbH Hannover, Bayer Schering Pharma AG Berlin and Novartis GmbH Basel
Industry excursions (e.g. Solvay AG, Hannover; Bayer AG, Research Center, Wuppertal) are regularly
taking place.
4. Success and measures for implementation
In 2006, sixteen students successfully finished the MD/PhD program (see above). Some of the finalists
continue to work at MHH or German universities (medical consultant, Postdoc etc.). Nine of them
already plan or went to work as Postdocs abroad (Canada. UK, USA, China, Switzerland, Sweden).
The MD/PhD program has established an ALUMNI organization and student’s network. In 2006, the
first Alumni newsletter was created. Furthermore, an Alumni survey was performed, which showed
very positive responses.
The MD/PhD program plays a key role (scientific, organization) in Hannover Biomedical Research
School (HBRS).
In 2006, MHH was very successful in the German Excellence Initiative. HBRS (with its MD/PhD
program „Molecular Medicine“) will be supported with 5 Million Euro for the next five years. This
includes the position of the scientific coordinator Dr. Kruse, 25 „half“ PhD stipends (18 months) per
new year, language teachers, student tutors, marketing, invitation of guest lecturers, soft skills, summer
schools, teaching aids, flexible funds, selection processes, travel of coordinators, support of student’s
travel to congresses, child care.
Furthermore, the accreditation (see above) implements the program.
The program was very successful in gaining sponsors, either for the annual workshop, the year book or
for student’s grants (see list on page 6). A sponsoring concept as well as special flyers were developed.
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II. Measures and Results The MD/PhD Program “Molecular Medicine“ started in winter semester 2000/01. From 2002 to 2006,
the program was supported by the DAAD/DFG by means of the “International Promotion Program”
(IPP). From 2007, the program will be supported by means of the German Excellence Initiative for the
Hannover Biomedical Research School (HBRS).
1. Personnel
Within the IPP the posts for a scientific coordinator (full time) and funds for assistant students (see
“non scientific care”; 10 hours/week) have been granted.
1.1. Scientific collaborators and administrative personnel
Since 01.05.2002, Dr. Susanne Kruse has been working on the program as scientific coordinator. She
has various tasks; she is responsible for the total coordination and organization of the MD/PhD
program and HBRS, e.g.
• Consultation of the PhD students and applicants
• Organization and coordination of the application and selection procedure
• Cooperation with the PhD commission and HBRS
• Processing of the PhD commission meetings
• Contact to supervisors and lecturers of the Medical School and cooperating institutes
• Public relations (articles, homepage design etc.)
• Marketing (flyers, poster, advertisements etc.)
• Fund raising (incl. sponsors); applications (DFG, BMBF etc.)
• Planing and coordination of the curriculum (including “Soft skills”)
• Organization of workshops/seminars
• Presentation of the seminar “Scientific Writing“
• Evaluation of seminars and tutorials
• Preparation of exams and coordination
• Organization of the inauguration, non scientific care and social activities
• Contact to DAAD and other PhD programs (esp. MD/PhD Network)
• Administration of the budget
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Mrs. Marlies Daniel works at the PhD Office (full time) as person in charge/correspondant. Her
position is financed by the Hannover Medical School.
Mrs. Daniel supports Dr. Kruse with the coordination und organization of the MD/PhD program. She
is responsible for the total correspondence, telephone calls, organization of the application procedure,
organization of events, taking care of the students (esp. during the training period: organization of
accommodation, banks, insurance etc.), statistics etc.
1.2. Tutors
In 2006, Tracey Gillman has been employed as assistant student on an hourly basis. She especially
takes care of the MD/PhD students in close cooperation with the “International Office”, helps at
German authorities, supports International evenings.
2. Language courses
Mrs. Petra Marotz has been employed as the German teacher since 01.10.2002 (hourly basis). Mr
Andre Brana was hired initially for the orientation weeks 2006. Both teach 2 hours/week. This
concerns a course for beginners and an advanced course (1 year experience). A total of over 20 PhD
students of HBRS participate in the courses.
3. Social Activities
• On 14.01.06 an Indian evening was organized.
• On 09.06.06, final exams of 7 MD/PhD students took place.
• On 12.07.06, eight students participated in an excursion to the biotech company ”Qiagen GmbH“
in Hilden, organized by the PhD program “Molecular Biology” in Göttingen.
• On 20.07.06, summer term was closed with an international barbecue for all PhD students,
lecturers and supervisors in HBRS.
• On 26.07.06, students visited the opera house Hannover (Ballet „Bolero“), in cooperation with the
International Office.
• On 09.09.06, a day excursion to Langeoog was organized in close cooperation with the
International office.
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• Orientation weeks (03.10.-16.10.06) were financially supported by the “WIN“ program (Welcome
in Niedersachsen) of Lower Saxony.
• The opening of term / welcome of new students was celebrated on 16.10.06. All students,
supervisors and lecturers of the MD/PhD program “Molecular Medicine“, the PhD program
“Infection Biology”, the Research training sites, the Master program “Biomedicine” as well as the
president of MHH and several guests (e.g. State secretary Dr. Lange, MWK; International
Advisory Board of HBRS) participated. Invited speaker was Prof. Kalden (University of Erlangen;
see also 6.), musical introduction by: Anna Piechotta + Band.
• On 10.11.06, the festive ceremony after the final exams took place. Invited guest speaker was Prof.
Dr. Yves Barral (ETH Zürich) (see also under 6.), musical introduction by Nora Teschner
(Cellotrio).
• On 12.11.06, an excursion/walk to the Süntel (Bad Münder) was organized.
• On 25.11.06, the Indian Diwali festival was celebrated.
• On 05.12.06, students visited the Christmas Market in Hannover city center.
• On 14.12.06, an international Christmas Party was celebrated with all students, supervisors and
lecturers of HBRS (all programs).
4. Organization of Educational Material
An HBRS study room was established. Laptops and major text books were purchased for student’s
use.
5. Marketing Measures
• A large number of ads were published in Nature, Science, New Scientist, Laborjournal etc. The
resonance was enourmous (400 applications).
• A year book 2005 was printed.
• On 21.02.06, an info meeting on the MD/PhD program was organized for students/candidates.
• Because of the accreditation, the MD/PhD program serves as a model and advisor for lots of other
national and international programs.
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6. Guest Lectures and additional colloquia
• From 12.01.-13.01.06, a workshop on „project management“ was organized by the GRK
„Characterization of pathophysiological animal models“. Four students of the MD/PhD program
participated.
• On 20.01.06, Dr. Kruse held the seminar “Scientific writing“ at MHH.
• From 06.-08.03.06 and from 06.-09.11.06, Prof. Hedrich and colleagues held the course “Animal
Experiments“ for HBRS students at MHH.
• From 09.-11.03.06, the annual Stephansstft Workshop (retreat) was taking place. Students had to
present and discuss their projects with all participants (students, supervisors, lecturers). In addition
assemblies of students as well as lecturers/supervisors were organized. The international evening
was planned for Friday. The workshop was financially supported by a number of sponsors.
• On 04.5.06 the written test for new applicants was given at MHH. In addition, tests were organized
in home countries of candidates.
• On 09.06.06, seven MD/PhD students had their final exams (public defenses; in English). At least
one external examiner was invited (Blackbourn, Birmingham, England; Schlitt, Regensburg;
Albrecht, Fribourg, Switzerland; Jeltsch, Bremen; Maronde, Frankfurt; Boileau, Paris, France;
Brand, Würzburg; Gessler, Würzburg). The official festive act was celebrated on 10.11.06 (see
below). During their stay in Hannover, some of the external reviewers gave guest lectures talking
about their own research results.
• From 16.-18.06.06, the workshop “Intercultural Communication“ took place in Springe (near
Hannover) in a joint effort of PhD programs in Göttingen and Hannover.
• Altogether 73 applicants were invited for interview in Hannover, New Delhi (India; DAAD office),
Hyderabad (India; CDFD) and Harbin (China) in June/ July 2006. Candidates had to give short
presentations of previous experimental work and were asked questions (total 20 min).
• From 20.-21.07.06, the workshop “Presentation techniques“ was offered by Prof. Dr. Dierks
(MHH). Aim was to prepare students for presentations on congresses, meetings etc.
From 18.-19.09.06, the seminar „Gene Technology Security“ was organized by Dr. Mertsching (Gene
Security Officer). The course was given at MHH for the third time in English. Participants receive a
certificate, which enablees to work as project leader in the field of genetechnology and working with
pathogenic microorganisms.
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• On 16.10.06, the opening of the new study year was celebrated. Guest speaker was Prof. Dr. J.
Kalden (University Clinics of Erlangen). In addition, members of the international advisory board
of HBRS were invited: Molin, Copenhagen, Denmark; Weber, Zürich, Schwitzerland; Cohen,
Dundee, Scotland.
• On 23.10.06, Prof. Melchers gave lecture in course of the HBRS curriculum.
• On 10.11.06, the final exams (public defense; in English) was organized for nine MD/PhD
students. At least one external examiner was invited (Johnsson, Münster; Bruder, Braunschweig;
Radeke, Frankfurt; Schäkel, Dresden; Niehues, Düsseldorf; Stürzl, Erlangen; Häußler,
Braunschweig; Seternes, Tromsoe, Norway). On the evening of the festive ceremony, Prof. Dr.
Yves Barral (ETH Zürich) was invited as guest speaker. Musical introduction was given by Nora
Teschner. During their stay in Hannover, some of the external reviewers gave guest lectures talking
about their own research results.
7. Travel
• From 22.-23.02.06, Dr. Kruse participated in the DAAD ECTS Workshop (Medicine/Public
Health) in Dresden.
• From 02.-03.05.06, Dr. Kruse and Prof. Dr. R. E. Schmidt travelled to the IPP (DAAD) annual
meeting in Bonn.
• From 18./19.05.06, Dr. Kruse participated in the meeting on „Alumni and graduate surveys”
organized by the university of Kassel.
• From 09.-12.06.06, Prof. Dr. R.E. Schmidt travelled to Calcutta (India) and the Indo-German
Science Center.
• From 03.07.-07.07.06, Dr. Kruse, Prof. Dr. C. Klein, Dr. Oliver Pabst and Prof. Dr. R. E. Schmidt
performed interviews with 30 Indian applicants in the DAAD office New Delhi and at CDFD
Hyderabad. From these applicants, nine were selected for the MD/PhD program.
8. Visits abroad by the graduate students
• Altogether 73 applicants were invited for interviews in June/July 2006 (see above).
• For all new students travel costs to Hannover were supported by the “WIN” program (see above)
• Overall, the MD/PhD students attended numerous meetings, congresses and short research stays
abroad. They were supported by the departments, DAAD, DFG etc.
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Year 2002
Aravind Sekhar
EducationCollege/University:1996-2002 Bangalore Medical College, Bangalore
Highest degree:M.B.B.S.(Bachelor of Medicine & Surgery)
Major Subjects:Medicine, Surgery, Obstetrics & Gynaecology
Projects/Research:Genes specifically expressed in intestine epithelium
Scholarships:JNCASR Summer Research Fellowship `98
Scientific Interests and Goals:Developmental biology
Hobbies and other interests:Travel, Reading, Rock Music, Calligraphy
First name:Aravind
Last name:
Sekhar
Date of birth:19.04.1978
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. A. GosslerMolecular Biology
Year 2003
Dorothea Dijkstra
Dorothea Gadzicki
Jaba Gamrekelashvili
Arnab Ghosh
Eric Hesse
Kumaravelu Jagavelu
Gustavo Salguero Lopez
Harini Nivarthi
Andri Pramono
Bishnudeo Roy
Tibor Veres
Anastassiia Vertii
First Name:Dorothea (Dorrit)
Last Name:Dijkstra
Date of Birth:28.10.1977
Country:The Netherlands
E-mail:[email protected]
Supervisors:Prof. Dr. T. WerfelDr. R. GutzmerDermatology
EducationCollege/University:1995-1999 Hogeschool IJsselland, Deventer, The
Netherlands1999-2001 Vrije Universiteit, Amsterdam, The
Netherlands
Highest degree:MSc (Drs.)
Major Subjects:Immunology, Dermatology, Pharmacology
Scientific Interests and Goals:To find out the role of anaphylatoxins C3a and C5a and their respective receptors in modulating the interaction between dendritic cells and T-lymphocytes in the skin. We will compare healthy subjects and patients with chronic inflammatory skin diseases as a model.
Hobbies and other interests:Parasitology (fascinating how they escape from host immune responses!), World Wildlife Foundation, Windsurfing, Skating, Friends, Drawing, Reading, Music, my parents dog Rocaille etc.
EducationCollege/University:1994-2001 Medizinische Hochschule Hannover, Germany
Highest degree:MD (Dr. med.)
Major Subjects:Genetics, Tumorigenesis
Projects/Research:Identification of secondary genetic changes in BRCA1/2-induced hereditary breast cancer development
Scholarship/Award:Junior Professorship for Hereditary Breast Cancer awarded bythe Lower Saxony Ministry of Science and Culture, Dorothea Erxleben Program (from November 2005)
Scientific Interests and Goals:To gain insight into fundamental molecular processes duringbreast cancer development, in particular of hereditary breastcancer, to improve the diagnostic procedures and adapttherapeutic strategies for a better prognostic outcome.
Hobbies and other interests:Literature, theatre, sports, drawing
Publications:- Gadzicki D, Müller-Vahl KR, Heller D, Ossegge S, Nöthen MM, Hebebrand J, Stuhrmann M (2004) Tourette Syndrome is not caused bymutations in the central cannabinoid receptor (CNR1) gene. Am J MedGenet B Neuropsychiatr Genet 127:97-103- Gadzicki D, von Neuhoff N, Steinemann D, Just M, Busche G, Kreipe H, Wilkens L, Schlegelberger B. (2005) BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib. Cancer Genet Cytogenet 159:164-7- Gadzicki et al. Communicating BRCA1 and BRCA2 genetic test results.(2006) J Clin Oncol 24:2969-70- Gadzicki D, Baumer A, Wey E, Happel CM, Rudolph C, Tönnies H, Neitzel H, Steinemann D, Welte K, Klein C, Schlegelberger B. (2006) Jacobsen syndrome and Beckwith-Wiedemann syndrome caused by a parental pericentric inversion inv(11)(p15q24). (2006) Ann Hum Genet 70:958-64. - Ansgar Gerhardus, Henriette Schleberger, Brigitte Schlegelberger, Dorothea Gadzicki. (2007) Diagnostic Accuracy of Methods for the Detection of BRCA1 and BRCA2 Mutations. A Systematic Review. Eur J Hum Genet (in press)
First name:
Dorothea
Last name:Gadzicki
Date of birth:07.10.1975
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. B. Schlegelberger,Cell and Molecular Pathology
EducationCollege/University:1996-2002 Tbilisi State Medical University, Tbilisi Georgia
Highest degree:MD
Major Subjects:Basic and tumor Immunology
Projects/Research:Influence of tumor cell death on tumor-specific immune responses
Scientific Interests and Goals:Mechanisms of immune tolerance & activation in tumor immunity
Hobbies and other interests:Table tennis, football, neuroscience.
Publications:Garbe AI. Vermeer B. Gamrekelashvili J. von Wasielewski R. Greten FR. Westendorf AM. Buer J. Schmid RM. Manns MP. Korangy F. Greten TF. Genetically induced pancreatic adenocarcinoma is highly immunogenic and causes spontaneous tumor-specific immune responses. Cancer Res. 2006 Jan 1;66(1):508-16.
Nizharadze N. Gongadze M. Sanikidze T. Gamrekelashvili J. Sumbadze C.Kevlishvili O. Effects of LPS on the proliferating processes in splenocytes. Proc. Georgian Acad. Sci., Biol., Ser. A., 2002, vol. 28, #5-6 pp. 573-576.
First name:
Jaba
Last name:Gamrekelashvili
Date of birth:07.01.1979
Country:Georgia
E-mail:[email protected]
Supervisor:PD.Dr. T. GretenDepartment of Gastroenterology,Hepatology & EndocrinologyMH Hannover
EducationCollege/University:1996-2001 Mysore Medical College, India
Highest degree:MBBS
Major Subjects:Medicine
Projects/Research:Mechanisms and modulation of anti-leukemia immunity
Scientific Interests and Goals:To obtain further insights into management of childhoodleukemia
Hobbies and other interests:Exploring Indian wildlife; Anthropology and development of languages
First name:
Arnab
Last name:Ghosh
Date of birth:09.05.1978
Country:India
E-mail:[email protected]
Supervisor:PD Dr. M. SauerPediatric Hematology and Oncology
EducationCollege/University:since 2005 Yale University School of Medicine, USA1996-2005 Hannover Medical School, Germany
Harvard University Medical School, USAUniversity of Birmingham, GBUniversity of Otago, New ZealandUniversity of Zurich, SwitzerlandUniversity of Cape Town, South Africa
Highest degree:MD
Major Subjects:Cell- and Molecular Biology
Projects/Research:Regulation of osteoblastogenesis and bone formation
Scientific Interests and Goals:Bone Biology
Scholarship:1. Endocrine Fellows Foundation Award2. DFG Research Fellowship3. I-lab Award, Aventis Foundation4. Hannelore Munke Research Award, MHH5. DAAD Fellowship6. Scholarship, Bayer Leverkusen Foundation
Hobbies and other interests:Sports, Literature
Publications:Hesse E, Rosenthal H, Brabant G, Laenger F, Gratz KF, Bastian L.Manuscript submitted
Hesse E, Moessinger E, Rosenthal H, Laenger F, Brabant G, Petrich T, GratzKF, Bastian L. J Bone Miner Res. 2007 Jan, Vol. 22, No 1. 158-62. Epub2006 Oct 2.
Hesse E, Jagodzinski M, Wehmeier M, Horne WC, Baron R. J Bone Miner Res. 2005 Sep, Vol. 20, S356
Hesse E, Musholt PB, Potter E, Petrich T, Wehmeier M, von Wasielewski R, Lichtinghagen R, Musholt TJ. Br J Cancer. 2005 Sep 5;93(5):565-70
Hesse E, Bastian L, Zeichen J, Pertschy S, Bosch U, Krettek C. Knee SurgSports Traumatol Arthrosc. 2006 Apr;14(4):335-9. Epub 2005 Jun 10.
First name:
Eric
Last name:Hesse
Date of birth:09.10.1975
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. R. Baron (PhD, DDS)Dr. W.C. Horne (PhD)(Orthopaedics and Cell Biology,Yale University)
Prof. Dr. C. Krettek (MD)(Trauma Surgery,Hannover Medical School)
EducationCollege/University:1997-1999 Bharathidasan University, Trichy, India
Highest degree:M.Sc.
Major Subjects:Microbiology
Projects/Research:Involvement of the p38-MK2 signaling pathway in artherogenesis
Scientific Interests:Developmental Biology
Hobbies and other interests:Photography, Lepidoptery, Travelling
Publications:Kumaravelu J, Shanmugasundaram GK, Unwala H, Ramamoorthi N, Banerjea AC. Genes and Immunity 2001; 2, 404-407.Ramamoorthi N, Kumaravelu J, Shanmugasundaram GK, Rani K, BanerjeaAC. Genes and Immunity 2001; 2, 408-410.
First name:Kumaravelu
Last name:Jagavelu
Date of birth:08.03.1976
Country:India
E-mail:[email protected]@hotmail.com
Supervisor:Prof. Dr. B. SchiefferCardiology
EducationCollege/University:1995-2001 Universidad Nacional de Colombia, Bogota Colombia
Highest degree:MD
Major Subjects:Cellular and molecular biology of cardiovascular diseases: Cellular and molecular mechanisms of angiogenesis.Role of progenitor cells in neovascularization
Projects/Research:Impact of biomechanical stretch in progenitor cell differentiation. Role of progenitor cells in Hypertension
Scientific Interests and Goals:My main goal is to apply the knowledge from research in molecular biology on the understanding of cardiovascular diseases. As a first approach I am working on in vitro and in vivomodels of vascular hypertension at a cellular and molecular level. It will open me new perspectives about potential applications of molecular technology and their impact on diagnostic and prevention strategies and more specific and effective treatments for these kind of diseases.
Hobbies and other interests:Take a walk by the mountains. Good music and literature.
First name:
Gustavo
Last name:Salguero
Date of birth:11.07.1978
Country:Colombia
E-mail:[email protected]
Supervisor:Prof. Dr. B. SchiefferCardiology and Angiology
EducationCollege/University:B.Sc. Biochemistry, Daulat Ram College, Delhi Univrsity.M.Sc. Biotechnology, Madurai Kamaraj University
Highest degree:Master
Major Subjects:Biotechnology, Biochemistry
Projects/Research:Molecular analysis of transcription factors involved in dendritic cell developmernt
Hobbies and other interests:Reading, Indian classical dance.
First name:
Harini
Last name:Nivarthi
Date of birth:15.08.1980
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. C. KleinPediatric Hematologyand Oncology
EducationCollege/University:1999 B.Sc. University of Indonesia, Indonesia2003 M.Sc. University of Indonesia, Indonesia
Highest degree:M.Sc. in Microbiology Medicine
Major Subjects:Cell Biology, Embryonic Stem Cell
Projects/Research:Analysis of Thrombopoetin function on hematopoeticdifferentiation in mouse embryonic stem cell
Scientific Interests and Goals:My interest unravelling molecular mechanism of hematopoiesis in embryonic stem cell.
Hobbies and other interests:Playing piano, watching movie.
Publications:
Rekiansyah M, Pramesyanti A, Bella B, Kosasih H, Ma‘roef CN, Tobing SY, Rudiman PI, Alisjahbana B, Endi TP, Green S, Kalayanarooj S, Rothman AL, Sudiro TM. Southeast Asian J. Trop. Med. Public Health. 2005 ;36(5) :1187-1197.
Wang Z, Skokowa J, Pramono A, Ballmaier M, Welte K.Ann NY Acad Sci. 2005; 1044:29-40.
First name:Andri
Last name:Pramono
Date of birth:21.08.1976
Country:Indonesia
E-mail:[email protected]
Supervisor:Prof. Dr. K. WeltePediatric Hematology and Oncology
EducationCollege/University:2001-2003 School of Biotechnology, Madurai Kamaraj University, Madurai, India
Highest degree:MSc in Biotechnology
Major Subjects:Biotechnology
Projects/Research:Contribution of B1 cells to the gut associated humoral immunity.
Scholarships •Received DBT (Department of Biotechnology, India) studentship during my MSc.• Junior research fellowship (JRF) awarded by Counsil for Scientific and Industrial Research (CSIR), India
Scientific Interests and Goals:I Have a particular interest in understanding the complexity ofthe regulation of immune responses.
First name:
Bishnudeo
Last name:Roy
Date of birth:04.08.1978
Country:India
E-mail:[email protected]
Supervisor:Dr. S. WeissMolecular ImmunologyHZI Braunschweig
EducationCollege/University:1996-2003 Semmelweis University Budapest, Hungary
Highest degree:MD
Major Subjects:Respiratory Immunology
Projects/Research:Interaction between pulmonary dendritic cells and nerves duringallergic airway inflammation
Scientific Interests and Goals:Understanding the mechanisms of cross-talk between thenervous and immune system and investigating the contributionof neuroimmune interactions to allergy
Hobbies and other interests:Music, literature, languages, hiking
Publications:Vannay A, Fekete A, Muller V, Strehlau J, Viklicky O, Veres T, Reusz G, Tulassay T, Szabo AJ. Kidney Blood Press Res. 2004;27(2):105-13.
Sander LE, Lorentz A, Sellge G, Coeffier M, Neipp M, Veres T, Frieling T, Meier PN, Manns MP, Bischoff SC. Gut. 2005 Nov 18
First name:
Tibor
Last name:Veres
Date of birth:11. 06. 1978
Country:Hungary
E-mail:[email protected]
Supervisor:PD Dr. BraunFraunhofer-Institute forToxicology and Experi-mental Medicine
EducationCollege/University:1993-1998 Kharkov State University -Kharkov, Ukraine2001-2003 Kadir Has University-Istanbul, Turkey
Highest degree:MSc in Biology
Major Subjects:Molecular Biology, Protein Interaction, Heat Shock Proteins
Projects/Research:Search for biological functions of Hsp25 phosphorylation
Scientific Interests and Goals:Hsps have essential cellular functions. This is the pillow thatprovides us with „soft landing“ once we fall unexpectedly. So I will try to learn how it works in details.
Hobbies and other interests:Alpine skiing (Bad Grund Club), Diving (PADI), Thai-Chi, meditation; Street cats (“Sokak Melek”, “SED”)
Publications:Memon A., Aktoprakligil D., Ozdemir A., Vertii A. Turk J. Bot 2001; 25:11-121
Duman BS, Turkoglu C, Akpinar B, Guden M, Vertii A, Dak E, Cagatay P, Gunay D, Buyukdevrim AS. Arch Pathol Lab Med. 2004 Aug;128(8):869-74.
Duman BS, Turkoglu C, Akpinar B, Guden M, Vertii A, Cagatay P, Gunay D, Sevim Buyukdevrim A. Ann Hum Biol. 2005 Sep-Oct;32(5):620-9.
A. Vertii, C. Hakim, A. Kotlyarov and M. Gaestel. J Biol Chem 2006 Sept; 281(37): 26966-26975.
First name:
Anastassiia
Last name:Vertii
Date of birth:03.08.1976
Country:Ukraine
E-mail:[email protected]
Supervisor:Prof. Dr. M. GaestelDr. A. KotlyarovInstitut für Biochemie/Physiologische Chemie
Year 2004
Rannar Airik
Abdul Mannan Baru
Adan Jirmo Chari
Sangeeta Chauhan
Mingmin Chen
Prajeeth C.K.
Gamze Kabalak
Khurshed Iqbal
Joanna Jagielska
Nonsikelelo Mpofu
Frederick Onono
Erkembulgan Purevdorj
Aeheli Choudhury Roy
Jessica Schwermann
Meera Shah
Anurag Singh
Kirsten Sommer
Leena Srivastava
Basant Thakur
Murat Ünalan
Fei Zhao
EducationCollege/University:1998-2004 University of Tartu, Estonia
Highest degree:M.Sc. in Developmental biology
Major Subjects:Developmental Biology, Molecular Biology
Projects/Research:Analysis of the function of the T-box gene Tbx18 in the murinekidney development
Scientific Interests and Goals:To get further insights into the mechanism of tissue and organ patterning in early mammalian development.
Hobbies and other interests:Movies, literature, etc.
Publications:Airik R, Bussen M, Singh MK, Petry M, Kispert A. Tbx18 regulates the development of the ureteral mesenchyme. J. Clin. Invest 2006; 116:663-674
First name:Rannar
Last name:Airik
Date of birth:20.07.1979
Country:Estonia
E-mail:[email protected]
Supervisor:Prof. Dr. A. KispertMolecular Biology
First Name:Abdul Mannan
Last Name:Baru
Date of birth:20.03.1979
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. G. BehrensClinical Immunology
EducationCollege/University:1996-1999 Bachelors in Microbiology, Mumbai University, India1999-2001 Masters in Microbiology, Mumbai University, India
Highest Degree:Masters in Microbiology
Major subjects:Genetics, Biochemistry, Biotechnology, Medical and Industrial Microbiology
Project / Research:1.) Roads to Presentation: Targeting the pathways in antigen uptake to dissect out mechanisms for cross presentation.2.) Differentiation and characterization of dendritic cells from HOXB4 transduced haematopoietic stem cells
Credentials and scholarships:• Topped Mumbai University in Microbiology at Bachelors level.• Worked as a Junior Research Fellow at TIFR, Mumbai, under Indo-Frenchcollaborative grant.• Worked as a Senior Research Fellow at TIFR, Mumbai under ICMR grant.
Scientific Interest and goals:To understand and characterize the cells and processes involved in immune protection.
Hobbies and other interests:Stage, Reading, Music.
PublicationsB.A. Mannan, K. Patel, I. Malhotra, B. Ravindran & Shobhona Sharma. How specific is the immune response to malaria in adults living in endemic areas? J. Vector Borne Dis. 2003; 40: 84-91.K. Aruna, Tirtha Chakraborty, Savithri Nambeesan, Abdul Baru Mannan, Alfica Sehgal, Seema R Bhalchandra and Shobhona Sharma. Identification of a hypothetical membrane protein interactor of ribosomal phosphoprotein P0. J. Biosciences 2004, 29:33-43.
EducationCollege/University:1994-1998 B.Sc (honours) Moi Univ.-Kenya2000-2003 M.Sc (Immunoparasitology) University of
Nairobi-Kenya
Highest degree:M.Sc (Immunoparasitology)
Major Subjects:Immunology,Virology and Parasitology
Projects/Research:Assessment and Modulation of dendritic cell induced CD8+T cell responses to HSV-1 epitopes. Differential antigenacquisition and presentation potential of murine splenic DC
Scientific Interests and Goals:Elucidation of scientific principles and their translation intobeneficial-societal use
Hobbies and other interests:Soccer, Chess and Charting with friends
First name:Adan
Last name:Chari Jirmo
Date of birth:19.12.1973
Country:Kenya
E-mail:[email protected]@mh-hannover.de
Supervisor:Prof. Dr. G. BehrensClinical Immunology
EducationCollege/University:2001-2003 University of Jammu, M.Sc in Biotechnology.
Highest degree:M.Sc. in Biotechnology
Major Subjects:Biotechnology
Projects/Research:1. Construction and characterization of cDNA library of Plantagoovata.2. Regulation of the turn over of mitotic cyclins and their role in the development of human malignancies.
Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology program. (2001-2003).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.
Scientific Interests and Goals:My main field of interest is cell biology and oncology, I want to study cell cycle and its regulation . I would consider myself to be successful in my ambition if I am in any way able to add to the knowledge that will ultimately help us to understand this fascinating area of biology.
Hobbies and other interests:Music, Movies, literature, etc.
First name:Sangeeta
Last name:Chauhan
Date of birth:16.05.1980
Country:India
E-mail:[email protected]
Supervisor:Dr. N.P. MalekMolecular Biology
EducationCollege/University:1999-2003 BSc. in Biological Science, Ningbo University, China2003-2004 MSc. in Molecular Genetics, the University of
Leicester, UK
Highest degree:MSc. in Molecular Genetics
Major Subjects:Genetics, Biochemistry and cellular biology
Projects/Research:The function of PDZ domain proteins in ion transport and the signalpathways by regulated cytoproteins.
Scientific Interests and Goals:To identify certain signal pathways on ion transport and theirdifferent physiological affection on ion absoption and secretion.
Hobbies and other interests:Relaxing and lying on somewhere with cool soft drinks and wonderful performance.
First name:Mingmin
Last name:Chen
Date of birth:05.10.1980
Country:China
E-mail:[email protected]
Supervisor:Prof. Dr. U. SeidlerGastroenterology, Hepatology & Endocrinology
EducationCollege/University:1997-2000 Bachelor of Science (Microbiology)
Osmania University, Hyderabad, India2001-2003 Master of Science (Biotechnology)
MKU, Madurai, India
Highest degree:Master of Science: Biotechnology
Major Subjects:Biotechnology
Projects/Research:Effects of MALP-2 on antigen presentation and cross-presentation by dendritic cells.
Scientific Interests and Goals:To translate molecular research into clinical diagnostics and therapeutics
Hobbies and other interests:Sports, Music
First name:Prajeeth
Last name:C.K
Date of birth:28.05.1979
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. G. BehrensClinical Immunology
EducationCollege/University:1998-2000 University of Greifswald, Germany2000-2002 University of Heidelberg, Germany2003 Diploma in Pharmacy
(University of Greifswald)
Highest degree:Dipl. pharm.
Major Subjects:Immunology, Human genetics
Projects/Research:Genetic risk factors of autoimmune diseases: Multiple Sclerosis, Sjögren’s syndrome and Systemic lupus erthematosus
Scientific Interests and Goals:My main interest is to study new targets and the development of therapeutics.
Hobbies and other interests:singing, guitar, meeting with friends, cinema
First name:Gamze
Last name:Kabalak
Date of birth:20.03.1979
Country:Germany
E-mail:[email protected]
Supervisor:PD Dr. T. WitteClinical Immunology
EducationCollege/University:1998-2000 M.Sc. In Biotechnology, HPU, Shimla, India.2001-2002 Diploma in Bioinformatics, JNU, Delhi, India.
Highest degree:M.Sc. in Biotechnology, Advanced Diploma in Bionfomatics
Major Subjects:Biotechnology and Computational Biology
Projects/Research:To unravel Telomeres and Telomerase activity in BovineEmbryos and Stem cells
Scientific Interests and Goals:To execute innovative and value-added research
Scholarships:Research Fellowsip by Council for Scientific and Industrial Reseach (CSIR), ICMR and Department of Biotechnology, India.
Hobbies and other interests:Travelling, Movies, Reading and Exploring „The Deutschland“.
First name:Khursheed
Last name:Iqbal
Date of birth:19.09.1978
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. H. Niemann
Department ofBiotechnology,Institute of Animal Sciences(FAL), Mariensee
EducationCollege/University:1996-1999 Bachelor of Science Honours Degree in
Biochemistry,University of Zimbabwe, Zimbabwe2002-2004 Master of Science Degree in Molecular Biology ,
Vrije Universiteit Brussel, Belgium
Highest degree:MSc in Molecular Biology
Major Subjects:Biochemistry and Molecular Biology
Projects/Research:Antigen-specific regulatory T-cells for control of auto- and alloimmune responses
Scientific Interests and Goals:To understand the molecular basis of human diseases and to apply this knowledge in the developmemnt of new therapies.
Hobbies and other interests:Traveling, Reading, Singing, meeting new people and learningabout new cultures
First name:Nonsikelelo
Last name:Mpofu
Date of birth:16.08.1977
Country:Zimbabwe
E-mail:[email protected]
Supervisor:Dr. E. JaeckelGastroenterology, Hepatology& Endocrinology
EducationCollege/University:1997 Jomo Kenyatta University of Agriculture and Technology-
Kenya, BSc(Biochemistry and Chemistry)
2003 University of Nairobi –Kenya MSc in Biochemistry
Highest degree:MSc in Biochemistry
Major Subjects:Biochemistry
Projects/Research:Farnesyl Transferase Inhibitor (FTI) Modulation of Topoisomerase
IIα Inhibition efficacy in Myloid Leukemia
Scientific Interests and Goals:Interested in Biological Signalling and its role in controlling
disease
Hobbies and other interests:Long distance Running, Eating free food, Arguing and Sleeping
Publications:Graham SP, Pelle R, Honda Y, Mwangi DM, Tonukari NJ, Yamage M, Glew
EJ, de Villiers EP, Shah T, Bishop R, Abuya E, Awino E, Gachanja J, Luyai AE, Mbwika F, Muthiani AM, Ndegwa DM, Njahira M, NyanjuiJK, Onono FO, et al. Theileria parva candidate vaccine antigensrecognized by immune bovine cytotoxic T lymphocytes. Proc Natl AcadSci U S A. 2006 Feb 21; [Epub ahead of print]
First name:
Fredrick Onyango
Last name:Onono
Date of birth:26.11.74
Country:Kenya
E-mail:[email protected]
Supervisor:PD Dr. C. ReuterHematology and Oncology
EducationCollege/University:1992-1998 MD National Medical University of Mongolia1999-2001 MSc Medical Genetics NMUM
Highest degree:MD, MSc
Major Subjects:Medical Genetics, Cell Biology
Projects/Research:ErB4 in fetal surfactant synthesis
Scientific Interests and Goals:To study molecular and cellular aspects of prenatal and postnatal disorders, to contribute to the development of biomedicalresearch in my country.
Hobbies and other interests:Sports, Travel
First name:Erkhembulgan
Last name:Purevdorj
Date of birth:23.05.1975
Country:Mongolia
E-mail:[email protected]
Supervisor:Dr. C. DammannPediatric Pulmonologyand Neonatology
EducationCollege/University:1999-2002 BSc (Hons.) Microbiology,Gargi College, Delhi
University, New Delhi, India2002-2004 MSc Biotechnology, AIIMS, New Delhi, India
Highest degree:MSc Biotechnology
Major Subjects:Microbiology, Immunology, Molecular Biology
Projects/Research:Analysis of the sequence of telomere dysfunction followed bytelomerase activation during aging and carcinogenesis
Scientific Interests and Goals:To translate molecular research into clinical diagnostics and therapeutics
Hobbies and other interests:Reading, Philately, Numismatics, Origami
Publications:Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, Rudolph KL. Cdkn1a deletion improves stem cellfunction and lifespan of mice with dysfunctional telomeres withoutaccelerating cancer formation. Nat Genet. 2007 Jan;39(1):99-105.
First name:Aaheli
Last name:Roy Choudhury
Date of birth:18.05.1981
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. K. L. RudolphGastroenterology, Hepatology& Endocrinology
EducationCollege/University:1998-2004 TFH-Berlin, Germany 2002 Dublin City University, Ireland2003 Baylor College of Medicine, Houston, TX, USA
Highest degree:Dipl. Ing. (FH)
Major Subjects:Pharmaceutical & Chemical Engineering
Projects/Research:Interaction between the p38 MAP kinase signaling cascade and Polycomb group proteins:Analysis of function and structure of MK2-Edr Polycomb complexes.
Scholarships:Grant from Hannover Biomedical Research School
Hobbies and other interests:Sports and travelling
First name:Jessica
Last name:Schwermann
Date of birth:13.09.1979
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. M. GaestelPhysiologicalChemistry
EducationCollege/University:2001- 2003: Master of Science in Biotechnology: MaduraiKamaraj University, Madurai., India.1998- 2001: Bachelor of Science ( Chemistry): VanasthaliVidyapith, Rajasthan, India.
Highest degree:Master of Science, Biotechnology
Major Subjects:Biochemistry, Molcular Biology, Immunology, Plant Biotechnology, Animal Biotechnology
Projects/Research:Structural-Functional analysis of cis-acting elements required formRNA stability.
Scientific AchievmentBest poster award on ´Characterization of DNA Gyrasemodulatory activity of Glutamate Racemase from Mycobacteriatuberculosis.Sugopa Sengupta, Meera Shah, V Nagaraja. in ITREID ( transcriptional meeting), 2005.
Scientific Interests and Goals:To get further insights to the proteins involved which areresponsible for mRNA regulation.
Hobbies and other interests:Music, dance, Reading, interest lies in doing science.
PublicationsSugopa Sengupta, Meera Shah, and Valakunja Nagaraja. Glutamate racemasefrom Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding. Nucleic Acids Res. 2006 November; 34(19): 5567–5576.
First name:
Meera
Last name:Shah
Date of birth:03. 05. 1980
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. H. HoltmannInstitute of PhysiologicalChemistry
EducationCollege/University:1999-2002 B.Sc. Hons. In Chemistry Banaras Hindu University,India2002-2004 M.Sc. Biotechnology, Madurai Kamaraj University,
India
Highest degree:M.Sc. In Biotechnology
Major Subjects:Biotechnology
Projects/Research:Elucidation of molecular mechanisms of Helicobacter VacA toxin.
Hobbies and other interests:Playing Games (table tennis, cricket), listening to music
First name:Anurag
Last name:Kumar Singh
Date of birth:06.02.1981
Country:India
E-mail:[email protected] [email protected]
Supervisor:Prof. Dr. U. SeidlerGastroenterology, Hepatology & Endocrinology
EducationCollege/University: Bsc,Poorvanchal University
Highest degree:M.Sc, JNU, New Delhi
Major Subjects:Biotechnology
Projects/Research:1. Structural and functional study of Actin binding proteins2. Cloning and expression of recombinant GMCSF in E. coli
Plasmid stability of GM-CSF gene in diff vectorsCenter For Biotechnology JNUSupervisor: KJ Mukherjee Associate Professor JNU
3. Cell BiologyMaintainance of Macrophage,Lymphocyte and Tcell linesMaintaince of entamoeba cell linesWorked with vibrio strains and also some experiments on
proteases
Scientific Interests and Goals: To go into infection biology feild.
Hobbies and other interests:Music
First name:Leena
Last name:Srivastava
Date of birth:02.02.78
Country:India
E-mail:[email protected]
Supervisor:Dr. E. KorenbaumBiophysical Chemistry
EducationCollege/University:M.Sc Biotechnology from School of Biotechnology, MaduraiKamaraj University
Highest degree:M.Sc Biotechnology
Major Subjects:Molecular Biology, cell biology, biochemistry and biotechnology.
Projects/Research:An approach towards structural determination of Cardamonmosaic virus.To generate SYMV resistance in Soybean crops using siRNAmediated gene silencing.
Scientific Interests and Goals:To do basic research in the field of cell and molecular biology. Post-transcriptional gene regulation.
Hobbies and other interests:Travel and Cricket
First name:Basant Kumar
Last name:Thakur
Date of birth:29.09.78
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. H. HoltmannPhysiological Chemistry
EducationCollege/University:1995-2002 Humboldt University Berlin, Medical Faculty
Charitè, Germany
Highest degree:MD (Dr.med.)
Major Subjects:Molecular- and Cell Biology, Differentiation
Projects/Research:Convergence of Wnt- and BMP Morphogen Signaling; CurrentStudies Focus on fluent and blocked Vertebrate CellDifferentiation Cascades; Exemplatory studied in two Model systems: in the endodermal derived Endocrine Gland, Thyroid, and in Haematopoiesis.
Scientific Interests and Goals:Understanding the molecular basis of multicellularity includingdifferentation and proliferation. My goal is to use a dual approachof standard laboratory techniques guided by theoretical models to identify key mechanisms in the regulatory complexity of Morphogens.
Hobbies and other interests:Fine art, Cooking/Sushi, Programming C++ and Perl,, MolluscShell Patterns, History of Physics and Biological Sciences.
Publications:Slominski A, Bortchkareva NV, Botchkarev VA, Chakroborty A, Luger T, Uenalan M, Paus R Biochim Biophys Acta 1998 19; 1448(1): 157-52 Slominski A, Bortchkareva NV, Botchkarev VA, Chakroborty A, Luger T, Uenalan M, Paus R Ann N Y Acad Sci 1999 20;885:448-450Ohnemus U, Uenalan M, Handjiski B, Paus R J Invest Dermatol 2003 122(1): 7-13Ohnemus U, Uenalan M, Conrad F, Handjiski B, Mecklenburg L, NakamuraM, Inzunza J, Gustafsson JA, Paus R Endocrinology 2005;146(3):1214-25.Skokowa J, Cario G, Uenalan M, Schambach A, Germeshausen M, BattmerK, Zeidler C, Lehmann U, Eder M, Baum C, Grosschedl R, Stanulla M, ScherrM, Welte K. Nat Med. 2006;12(10):1191-7
First name:Murat
Last name:Ünalan
Date of birth:31.10.1975
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. K. Welte, Pediatric Hematology & Oncology (formerly Prof. Brabant, Endocrinology)
EducationCollege/University:1997-2001 Huazhong Agricultural University, P.R.China2001-2004 Wuhan Institute of Virology, Chinese Academy of
Sciences
Highest degree:Master of Science
Major Subjects:Tumor immunology
Projects/Research:Identification of a dominant antigen of the murine pancreatic
tumor by SEREX, and characterize the antigen
Scientific Interests and Goals:Tumor research
Hobbies and other interests:Travelling and Movies
First name:Fei
Last name:Zhao
Date of birth:28.10.1978
Country:P.R.China
E-mail:[email protected]
Supervisor:PD. Dr. T.F. GretenGastroenterology, Hepatology& Endocrinology
year 2005
Mathias Christgen
Priyanka Dutta
Ursula Ehmer
Luis Guachalla Gutierez
Lydia Asrat Haile
Harshvardhan
Henoch Hong
Ananta Paine
Amrita Rai
Sumit Rathore
Mathias Rhein
Reena Singh
Inga Sörensen
Ratnesh K. Srivastav
Ujala Srivastava
Kathrin Steinwede
Shazad Nawaz Syed
Dong Wang
Alexander Wolf
Katja Zscheppang
EducationCollege/University:2004-2005: University Kiel, Germany, Institute of Pathology, Clinical Training (PJ).2003-2004: Howard Hughes Medical Institute, Cleveland, U.S.A., Research Scholar in Cancer Genetics.2000-2003: University Kiel, Graduate Student in Medicine. 1998-2000: University Halle, Germany, Undergraduate Student in Medicine.
Highest degree:M.D
Major Subjects:Medicine
Projects/Research:Isolation of characterization of clonogenic breast cancer cells
Awards & Scholarships:2003: Scholarship of the German Academic Exchange Service.2002: Abraham-Buschke-Award of the Charité Berlin.2001: Scholarship of the „Studienstiftung“.1995: Jugend-Forscht-Award in chemistry.
Scientific Interests and Goals:Yo Berra, an American baseball star of the 1950ties, once said: “What gets us into trouble is not what we don‘t know. It‘s what we know for sure that just ain‘t so.“ In my opinion, this pertains to science, too. Hence, it is my goal, that our research on epithelial malignancies truly tackles the nature of cancer.
Hobbies and other interests:Soccer, funk music and cross country skiing.
PublicationsFrom previous work
First name:Matthias
Last name:Christgen
Date of birth:27.01.1979
Country:Germany
E-mail:[email protected]
Supervisors:PD. Dr. U. Lehmann / Prof. Dr. H.H. Kreipe, Pathology
EducationCollege/University:2003-2005 All India Institute for Medical Sciences (AIIMS)
Highest degree:M.Sc. in Biotechnology
Major Subjects:Biotechnology
Projects/Research:1. Further characterize the contribution of p53 to cytokine receptor mediated signaling and cellular phenotype in 32Dwt and 32D p53hypo cells. 2. Elucidate cellular components involved in myeloiddifferentiation
Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology programe (2003-2005).
Scientific Interests and Goals:My main field of interest is Haematopoesis, I want to study thebiology of the haematopoetic cytokine receptor signalling. I would consider myself to be successful in my ambition if I am inany way able to add to the knowledge that will ultimately help us to understand this fascinating area of biology better.
Hobbies and other interests:Music, books, Movies, literature, etc.
First name:Priyanka
Last name:Dutta
Date of birth:12.09.1981
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. M. Scherr/ Prof. Dr. M. EderHaematology
EducationCollege/University:1997-2004 Hannover Medical School
Highest degree:MD
Major Subjects:Gastroenterology and hepatology, human genetics, metabolism
Projects/Research:Identification of functional relevant single nucleotide polymor-phisms in drug metabolizing enzymes (UDP-glucuronosyltrans-ferases, UGT). Regulation studies on UGT in a transgenic mouse model
Scientific Interests and Goals:Molecular genetics, impact of genetic polymorphisms on metabolism, regulation of metabolic enzymes.
Hobbies and other interests:Reading, sports, travelling, cooking.
Publications:
Vogel A, Kneip S, Barut A, Ehmer U, Tukey RH, Manns MP, Strassburg CP. Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. Gastroenterology 2001; 121: 1136-1144
Vogel A, Ockenga J, Ehmer U, Barut A, Kramer FJ, Tukey RH, Manns MP, Strassburg CP. Polymorphisms of the carcinogen detoxifying UDP-glu-curonosyltransferase UGT1A7 in proximal digestive tract cancer. Z. Gastroenterol. 2002, 40(7): 497-502
Ehmer U, Vogel A, Schütte JK, Krone B, Manns MP, Strassburg CP. Variation of hepatic glucuronidation: novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4. Hepatology, 2004; 39(4): 970-977
First name:Ursula
Last name:Ehmer
Date of birth:22.9.1978
Country:Germany
E-mail:[email protected]
Supervisor:PD Dr. C. S. StrassburgGastroenterology, Hepatology & Endocrinology
EducationCollege/University:1998-2003 Universidad Mayor de San Andres. Licenciado in
Biochemistry. La Paz, Bolivia2004-2005 University of Westminster. MSc in Medical
Biotechnology. London, UK
Highest degree:M.Sc. in Medical Biotechnology
Major Subjects:Biochemistry
Projects/Research:Analysis of the role of oxidative stress and the cell cyclecheckpoint protein g0s2 in organismal ageing.
Scholarships:Full International Scholarship. University of Westminster (2004-2005).
Scientific interests and goals:Ageing, in its broad spectrum of effects, will be the ultimate cause of death of mankind after rather curable diseases in developingcountries are controlled. Since ageing can be considered a multifactorial process, different models to study the decay of life and strategies to contrarest it are being developed. It is probablythe oxidative stress and telomere shortening theories that are themost important and well studied models of ageing, and here I want to establish plausible links between these two multistepprocesses in an in vivo setting with the perspectives to keepprogressing in the field of regenerative medicine.
Hobbies and other interests:Music, brewery, evolution, human relations.
First name:Luis Miguel
Last name:Guachalla Gutierrez
Date of birth:03.03.1980
Country:Bolivia
E-mail:[email protected]
Supervisor:Prof. Dr. K.L. RudolphGastroenterology, Hepatology& Endocrinology
EducationCollege/University:2001-2003 National Institute of Pharmaceutical Education and Research, M.Sc in Pharmacology.
Highest degree:M.Sc. in Pharmacology
Major Subjects:Pharmacology
Projects/Research:T cell based therapies in mouse model of colitis associatedColon cancer
Scientific Interests and Goals:To get further insights in to the molecular causes of diseases.
Hobbies and other interests:Music, Movies, travelling
Publications:Srinivasan K, Viswanad B, Asrat L, Kaul CL, Ramarao P. Combination of high-fat diet fed and low dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.Pharmacol Res.2005 Oct;52(4):313-20.
First name:Lydia
Last name:Haile
Date of birth:10.03.1979
Country:Ethiopia
E-mail:[email protected]
Supervisor:PD. Dr. T. GretenGastroenterology, Hepatology& Endocrinology
Education2002-2004; Masters in Life Sciences from Jawaharlal Nehru University (JNU), New Delhi.2004-2005; Doctoral student at Indian Institute of Science (IISc), Bangalore.
Highest Degree:M.Sc. in Life Sciences.
Major Subjects:Molecular Cell Biology and Immunology.
Projects/Research:1. Survival of syngenic and xenogenic erythrocytes in mice, Immune functioning and modulation.2. Initiation of replication in single stranded positive sense RNA viruses.
Scholarship:Junior Research Fellowship (JRF-NET) awarded by Council forScientific and Industrial Research (CSIR), India.
Scientific Interests and Goals:I am interested in induction of aging and its molecluar aspects.The main mediators of aging are the immune system and the Nervous system or Brain. In the past time the average age of human being has increased continously and so the incedences of age related disordes like Parkinsons disease and Alzehimers disease that target Brain; have also increased parallely. My work is focused on the induction of aging and ist effect on development and progression of such disorders.
Hobbies and other interests:Music, Cricket, Movies and Poetry.
Name:Harshvardhan
Date of Birth:01.01.1982
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. L. K. RudolphGastroenterology, Hepatology & Endocrinology
EducationCollege/University:2000-2005 University of Heidelberg in Biology.2004-2005 Diploma Thesis at the DKFZ (German CancerResearch Center)
Highest degree:Diploma in Biology
Major Subjects:Molecular Biology, Cell Biology, Biochemistry
Projects/Research:Study how HIV-1 affects and impairs the innate immunityfocusing on natural killer cells and dendritic cells; establishing an in vitro model for the interaction of highly purified dendritic cellsand natural killer cells
Scientific Interests and Goals:Immunology and Virology are my main fields of interest.
Hobbies and other interests:Playing piano, Basketball, Christian Literature, Cooking and Eating etc.
First name:Henoch Sangjoon
Last name:Hong
Date of birth:08.04.1980
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. R.E. Schmidt/Dr. H. HeikenClinical Immunology
EducationCollege/University:2002-2004 University of Pune , M.Sc. in Bioinformatics
Highest degree:M.Sc. in Bioinformatics
Major Subjects:Bioinformatics
Projects/Research:Identification of immunotherapeutically targetable peptide
antigens for individualized leukemia treatment .
Scholarships:G.N. Ramchandran Scholarship , awarded by CBT, India (2002-
2004).
Scientific Interests and Goals:My areas of interest are immunology and cancer reseach . As a scientist my dream is to find effective treatments for various
infectious and systematic diseases .
Hobbies and other interests:Painting, movies, music, literature .
First name:Ananta
Last name:Paine
Date of birth:17.08.1979
Country:India
E-mail:anantapaine24@@yahoo.com
Supervisor:Prof Dr. B. Eiz Vesper Transfusion Medicine
Education
College/University:1999-2002 Banaras Hindu University, B.Sc. (Hons) in Chemistry2002-2004 Indian Institute of Technology Roorkee, Roorkee M.Sc. in Biotechnology.
Highest degree:M.Sc.
Major Subjects:Biotechnology
Projects/Research:1. Structure and function of Dynamin and Dynamin Related Proteins.2. Worked as J.R.F at National Centre for Cell Science,Pune India. I was working on project “ Differentiation of mouse embryonic stem cells (mES) into Pancreatic ß cell like clusters (2004-05)3. Project work on “ Studies on acid and salt tolerance of Rhizobial strains isolated from legumes(2004)4. Worked on cloning ,expression and characterization of phosphoenol pyruvate carboxylase,UV survival and thermoluminescence of wild and mutants of Anacystis nidulans (2003).
Scholarships:1. Junior Research Fellowship (JRF) awarded by Council for Scientific and Industrial Research (CSIR), India. Among top 20%2. Qualified Graduate Aptitude Test in Engineering (GATE). All India Rank 563. Received Biotechnology Scholarship for Masters (2002-04),it was sponsored by DBT ,India.
Scientific Interests and Goals:To learn more about Dynamins.
Hobbies and other interests:Music , Dress designing and Roaming
First name:Amrita
Last name:Rai
Date of birth:15-07-1980
Country:India
E-mail:[email protected]
Supervisor:Prof. D.J.MansteinBiophysical Chemistry
EducationCollege/University:1999-2004 Johann Wolfgang Goethe University of Frankfurt
Highest degree:Diploma of Biochemistry
Major Subjects:Biochemistry, Biophysical Chemistry
Projects/Research:1. Mouse models for neurotrophin receptor- induced leukemia2. Functional analysis of deregulated neurotrophin receptoractivation in leukemia3. Validation of potential therapeutic approaches to treatneurotrophin- induced leukemia
Scholarships:PhD stipendship of the German Jose Carreras LeukemiaFoundation (Deutsche Jose Carreras Leukämie- Stiftung)
Scientific Interests and Goals:My scientific focus is leukemia. We try to understand the basicmechanisms that lead to leukemogenesis through oncogenicderegulation of neurotrophin receptors. The goal is to utililzemouse models for the discovery of new therapeutic approaches to treat human neurotrophin- related leukemia.
Hobbies and other interests:Music(guitar), Aikido, english language, sports
First name:Mathias
Last name:Rhein
Date of birth:10.02.1978
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. C. BaumDr. Z. LiExperimental Hematology
First name:Reena
Last name:Singh
Date of birth:05.08.1981
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. A. KispertMolecular Biology
EducationCollege/University:2003-2005 Madurai Kamaraj University
Highest degree:M.Sc. in Biotechnology
Major Subjects:Biotechnology
Projects/Research:1. Study of expression of pigmentation genes in skin and their
functional role in melanogenesis.2. Cloning of Thaumatin like protein and Chitinase gene in binary
vector and transformation of indica rice variety White Ponni to enhance sheath blight resistance.
Scholarships:1. Fellowship awarded by DBT,india for selection in All india
combined M.Sc. biotechnology programme (2003-2005).2. Junior Research Fellowship (JRF) awarded by Council for
Scientific and Industrial Research (CSIR), India (2005).
Scientific Interests and Goals:My main field of interest is Developmental Biology, I want to
investigate role of T-box genes during heart development.
Hobbies and other interests:Music, dance, love to be in the laps of nature,
EducationCollege/University:2000-2005 University of Applied Sciences Hamburg2003-2004 Biotechnology Research Institue, Montreal, Canada
Highest degree:Diploma in Biotechnology
Major Subjects:Biotechnology:Applied Micro-and Molecular Biology
Projects/Research:1. Expression, Purification and Characterisation of the bacteriocinpediocin PA-1 from Pichia pastoris (BRI, National Research Council of Canada, Montreal)2. Lesion induced plasticity in the spinal cord of adult zebrafish (dDiploma thesis, Center of Molecular Neurobiology Hamburg)3. Analysis of Dll1 function in the vascuar system
Scholarships:1. Karl-Heinz-Ditze Stiftung: full scholarschip for studyingabroad2.Scholarship from DAAD for study expenses in Canada.
Scientific Interests and Goals:My main field of interest is development ofthe vascular system. I want to study genes which are involved in vasculogenesis and angiogenesisy. I would like contribute a small step to thedevelopment of new therapies for vascular diseases in humans.
Hobbies and other interests:Hockey, Fitness, Traveling
Publications:A. Limbourg, M.Ploom, D. Elligsen1, I.Sörensen, T. Ziegelhoefer, A. Gossler, H.Drexler1 and FP. Limbourg. The Notch Ligand Delta-like 1 (Dll1) is Essential for Postnatal Arteriogenesis, Circulation Research, 2007
First name:Inga
Last name:Sörensen
Date of birth:04.07.1980
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. A. GosslerMolecular Biology
EducationCollege/University:2001-2003 Madurai kamaraj University M.Sc in Biotechnology.
Highest degree:M.Sc. in Biotechnology
Major Subjects:Biotechnology
Projects/Research:1.Expression, refolding and purification of ßketo acyl ACP reductase an indespansible enzyme of Fatty acid biosynthesisof plasmodium.2.Cloning, subcloning and expression of PKS antibiotics in E.coliexpression system.3. Refolding and purification of C and Z sigma factor of Micobacterium tuberculosis.
Scholarships:1. Awarded by DBT,india for selection in All india combinedM.Sc. biotechnology programe (2001-2003).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.3. R&D Assistantship from JNCASR, Bangalore, India.4. 40th rank in GATE coducted by Indian institute of technology India in 2003.
Scientific Interests and Goals:My main field of interest is Biochemistry.
Hobbies and other interests:Music, Cricket, Movies, literature, etc.
First name:Ratnesh
Middle nameKumar
Last name:Srivastav
Date of birth:11.10.1979
Country:India
E-mail:[email protected]
Supervisor:Dr. R. Niedenthal/ Prof. Dr. M. GaestelPhysiological Chemistry
EducationCollege/University:1998-2001 Bachelors in Science from University of Lucknow,
Lucknow, India.2001-2003 Masters in Biochemistry from University of Lucknow,
Lucknow, India
Highest degree:M.Sc. in Biochemistry
Major Subjects:Biochemistry
Projects/Research:Production and characterisation of the Est1 knockout mouse and
the role of Rad9 in replicative senescence.
Scholarships & Awards:Prof. P.S. Krishnan gold medal for securing first position in
mastersCouncil for Scientific and Industrial research(CSIR) and Indian
council of Medical Research (ICMR) fellowship
Scientific Interests and Goals:The elucidation of senescence mechanisms in in vitro and in vivo
systems.
Hobbies and other interests:Music, Reading etc.
First name:Ujala
Last name:Srivastava
Date of birth:03.06.1980
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. L.K. RudolphGastroenterology, Hepatology& Endocrinology
EducationCollege/University:2000-2005 University Bremen2005 Diploma in Biology (University Bremen)
Highest degree:Dipl. Biology
Major Subjects:Immunology, Microbiology
Projects/Research:Investigation of the role of lysosomal cathepsins in mycobacterialinfections of the lung
Scientific Interests and Goals:To understand the host immune response in engendering protective immunity against bacterial and viral infections and Iam also interested in the strategies of pathogens to evade the immune system. .
Hobbies and other interests:music, guitar, theatre, movies…
First name:Kathrin
Last name:Steinwede
Date of birth:06.12.1980
Country:Germany
E-mail:[email protected]@MHH.de
Supervisor:PD Dr. U. MausPneumology
EducationCollege/University:1999-2000 MSc –I Botany (Nagpur University)2000-2002 MSc in Biochemitry (Nagpur University)
Highest degree:MSc (Biochemistry)
Major Subjects:Biochemistry, Biotechnology, Immunology
Projects/Research:1. “Establishment of COS cell Transfection and Erythrocyte Adhesion
Assay for Plasmodium vivax Erythrocyte Binding Protein”.2. “Standardization of AmpRT Assay using HIV-1 genome”3. Understanding the molecular mechanism, genetics and functional
genomics of insecticide resistance Helicoverpa armigera.
Scholarships:1. Indian Council for Medical Research Junior Research Fellowship
(ICMR JRF), July 2003.2. PhD fellowship from German Research Council (GRK-705).
Scientific Interests and Goals:My focus in PhD research is Molecular Immunolgy. I would like to
decipher molecular regulation in autoimmune diseases withspecial emphasis on AIHA so that the knowledge can betranslated into effective therapeutic scheme.Only more research – result oriented, would help invigorate my curiosity and take me to an advanced stage of standpoint.
Hobbies and other interests:Outdoor Sports, Music,Technologies, etc.
First Name:Shahzad Nawaz
Last Name:Syed
Date of birth:02.06.1978
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. J.E. GessnerClinical Immunology
EducationCollege/University:1997-2002 Peking Union Medical College.
Highest degree:M.D.
Major Subjects:Immunology/Infectious Disease
Projects/Research:Pathogenic roles of keratinocytes in cutaneous lupuserythematosus.
Scholarships:Les Amis de Pasteur,Pasteur Institute of Brussels
Scientific Interests and Goals:Besides interests in Immunology/Infectious disease, I wouldelucidate the role of keratinocytes in the pathophysiology of lupus erythematosus especially the cross presentation of extracellular antigens to MHC-I restricted CD8 T cells.
Hobbies and other interests:Literature,History,Music,Econimy, Philosophy and Linguistic.
Publications:1.Wang D, Liu Baofeng. Malaria Vaccine, p.355-401.Vaccinology. Editor in chief: Zhang Yanling, Science Press of China, Beijng, PR China, 2004
2.Wang D, Mao YH, Wang H. Molecular cloning of P.y. dynamin-like protein PyDyngene and the immunological character of its domains. ACADEMIAE MEDICINAE SINICAE. 2003;25(2):176-80
First name:Dong
Last name:Wang
Date of birth:25.10.1975
Country:China
E-mail:[email protected]
Supervisor:Prof. Dr. M. WittmannDermatology
EducationCollege/University:1999-2004 University Hannoversince 2004 Medical School Hannover
Highest degree:Dipl. Biochemistry
Major Subjects:Biochemistry, Organic Chemistry, Pharmacology
Projects/Research:Analysis of the mechanism by which the yersinia enterocolitica
virulence factor Yop.P inhibits host cell protein kinases
Scientific Interests and Goals:to research the way like the virulence factor Yop.P can inhibit
simultaenously several inflammation pathways
Hobbies and other interests:climbing, hiking, canoeing, travelling by bike, chess, Music
Publications:Tsikas D, Wolf A, Frolich JC. Simplified HPLC method for urinary and circulating
creatinine. Clin Chem. 2004 Jan;50(1):201-3.
First Name:Alexander
Last Name:Wolf
Date of birth:14.03.1979
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. M. KrachtPharmacology
EducationCollege/University:2000-2005 University of Applied Sciences, Senftenberg.
Highest degree:MSc in Biotechnology
Major Subjects:Biotechnology
Projects/Research:ErbB4 receptor activation, trafficking, and function in fetal lung type II cells
Scientific Interests and Goals:To get further insights in the mechanisms by which ErbBreceptors regulate processes of fetal lung maturation.
Hobbies and other interests:Meeting with friends, Movies, Reading
Publications:Zscheppang K, Korenbaum E, Bueter W, Ramadurai SM, Nielsen HC, Dammann CE. Pediatr Pulmonol. 2006; 41(12): 1205-12Zscheppang K, Liu W, Volpe MV, Nielsen HC, Dammann CE. Am J Physiol. 2007, submittedBueter W, Dammann O, Zscheppang K, Korenbaum E, Dammann CE. Cytokine. 2007, in pressLiu W, Zscheppang K, Murray S, Nielsen HC, Dammann CE. BiochimBiophys Acta. 2007, submitted
First name:Katja
Last name:Zscheppang
Date of birth:31.08.1981
Country:Germany
E-mail:[email protected]
Supervisor:Dr. C. DammannPediatric Pulmonologyand Neonatology
year 2006
Hengameh Adollahpour
Nora Anderson
Arpita Baisantry
Hari Balaji
Anne Gompf
Maria Gschwandtner
Kshama Gupta
Dhivya Haridass
Niels Heinz
Wolfgang Koestner
Snehlata Kumari
Tobias Mätzig
Manoj Menon
Nidhi Narain
Natalie Naue
Daniel Poehnert
Wilhelm Walter
Kristina Wiege
Xiangyue Zhang
EducationCollege/University:1997-2005 Tehran University of Medical Sciences2005- 2006 research assistant in medical school of Hannover
Highest degree:Medical Doctor
Major Subjects:Molecular Medicine
Projects/ResearchTo study different functions of transcription factor “Gfi1”.
Scientific Interests and Goals:Immunology, Hematology , Oncology and Immunodeficienysyndromes
Hobbies and other interests:Music, travelling, Movies, literature, ….
First name:Hengameh
Last name:Abdollahpour
Date of birth:16.10.1979
Country:Iran
E-mail:[email protected]
Supervisor:Prof. Dr. C. KleinPediatric Hematology &Oncology
EducationCollege/University:1998-2005 Hannover Medical School (MHH), Germany2003-2003 Doctoral student, Department of Anesthesiology,
University of Colorado: Health Sciences Center, Denver, CO, USA.
Highest degree:State Examination (Physician)
Major Subjects:Medicine
Projects/Research:NMR- and MS-based metabonomic approaches to assess biomarkers of liver toxicity.
Scientific Interests and Goals:My specific focus of interest is the connection between aberrations of the cellular metabolism and pathological conditions, including the metabolic response to toxic injury andits role in malignant transformation and maintenance of the malignant phenotype. By working in the research field of metabonomics I hope I will be able to contribute to translation of basic research into advantages for clinical practice.
Hobbies and other interests:Hiking, Literature, Music, Movies
Publications:Anderson, N. and Borlak, J., Drug-induced phospholipidosis FEBS Letters, p.5533-40580 volume 23 (2006).
Anderson, N. Jelena, M., Serkova, N., Time dependent effects of Imatinib on human leukemia cells. Journal of Cancer Research and Oncology, p. 63, volume 130, supplement 1 (2004).
Gottschalk, S., Anderson, N., Hainz, C., Eckhardt, S.G., Serkova, N. Imatinib (STI571) – mediated changes in glucose metabolism in human leukemia BCR-ABL- positive cells. Clinical Cancer Research, p. 6661-6668 volume 10 (2004).
First name:Nora
Last name:Anderson
Date of birth:07.01.1979
Country:Germany
E-mail:Nora.andersonweb.de
Supervisor:Prof. Dr. J. BorlakMolecular ToxicologyFraunhofer Institute, ITEM
EducationCollege/University:2001-2004 : B.Sc. (Hons) Microbiolgy, Gargi College, Delhi University,
New Delhi, India.2004-2006 : M.Sc. Biotechnology, AIIMS, New Delhi, India.
Highest degree:M.Sc. in Biotechnology.
Major Subjects:Biotechnology, Molecular Biology, Immunology, Cell Biology
Projects/Research:1. Analyze the functional consequences of the deletion of candidate
genes of the DNA damage pathway on the lifespan, organ homeostasis and stem cell function in telomere dysfunctional mice.
2. Analysis of a telomerase activating compound (GRN TAT0002) in improving liver regeneration.
Awards and Scholarships:1. Junior Research Fellowship (JRF) awarded by Council for Scientific
and Industrial Research (CSIR), 2006, India. 2. Junior Research Fellowship (JRF) awarded by Department of
Biotechnology (DBT-JRF),2006, India.3. Junior Research Fellowship (JRF) awarded by Indian Council of
Medical Research, 2006, India.4. Secured University 2nd rank in B.Sc. (Hons) Microbiolgy (2001-
2004), Delhi University.5. Award for Best Student securing highest aggregate in South Campus
(2001-2004), Delhi University.
Scientific Interests and Goals:Telomere shortening likely influences human ageing by limiting stem cell function, regenerative reserve and organ homeostasis. The checkpoints that are induced by telomere dysfunction on stem cell level are unknown. The characterization of such checkpoints could help to define therapeutic targets aiming to improve regenerative reserve and organ homeostasis during ageing.
Hobbies and other interests:Reading, Listening to music.
First name:Arpita
Last name:Baisantry
Date of birth:14.10.1984
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. K. L. RudolphGastroenterology,Hepatology& Endocrinology
EducationCollege/University:2001-2003 Madurai Kamaraj University M.Sc in Microbial Gene Technology
Highest degree:M.Sc. in Microbial Gene Technology
Major Subjects:Molecular Biology
Projects/Research:1. Rutin like compound from Punica granatum and itsbioactivities.2. Mechanisms of apotosis induced by phytochemicals in BC-8 cells3. cDNA library screening of AK-5 tumor for a ligand for theactivating NK cell receptor NKRP2
Scholarships:1. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.3. GATE scholarship
Scientific Interests and Goals:Translational Research ‘From bench to bedside’(and hopefully from mouse to man) : the ability to rapidly transfer new basic scientific knowledge to biomedical knowledge, in order to generate advanced diagnostic and therapeutic applications, at the same time offering new investigation tools. And in pursuit of that I would like to study common mechanisms in inflammation and cancer.But if someone would ask me to state my research interests in one word, then that would be ‘Immunology’
Hobbies and other interests:Music, dance, history ,literature and sports.
First name:Hari
Last name:Balaji
Date of birth:09.11.1981
Country:India
E-mail: [email protected]
Supervisor:Prof. Dr. T. WerfelDermatology
EducationCollege/University:2000-2006 Free University of Berlin
Highest degree:Diploma in Biology
Major Subjects:Genetics, Biochemistry & Molecular Biology, Cell Biology, Immunology
Projects/Research:Investigation of telomere dysfunction-induced environmentalchanges and their influence on hematopoietic stem cell functionand engraftment.
Scientific Interests and Goals:To understand the molecular and cellular basis of ageing and to improve the function of endogenous and also transplanted stem cells in the treatment of regenerative dysfunctions.
Hobbies and other interests:Music, Dancing, Inline Skating, Literature, …
First name:Anne
Last name:Gompf
Date of birth:14.03.1980
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. K.L. RudolphGastroenterology, Hepatology & Endocrinology
EducationCollege/University:2002-2006 IMC University of Applied Sciences Krems, Austria
Medical and Pharmaceutical Biotechnology
Highest degree:Dipl.Ing. (FH)
Major Subjects:Medical Biotechnology
Projects/Research:Investigation of the role of histamine receptor 4 (H4R) in comparison to other histamine receptors in allergic inflammationof the skin
Scientific Interests and Goals:During my PhD studies I want to get more in depth knowledge about the immunology of allergic skin inflammation in general. Particularly I will deal with H4R, which seems to play a role inthe pathogenesis of allergic diseases since it is expressed on cells of the peripheral immune system. Since the expression profile and role of this receptor - in health and disease - have not been adequately investigated and understood till now, the explorationof this receptor is the goal of my future work.
Hobbies and other interests:Having fun, Meeting friends, Reading and some sports
.
First name:Maria
Last name:Gschwandtner
Date of birth:25.12.1983
Country:Austria
E-mail:[email protected]
Supervisor:Prof. Dr. T. Werfel/Dr. R. GutzmerDermatology
EducationCollege/University:M.Sc. Biotechnology [M. Biotech, 2003-2005], Department of
Biotechnology, AIIMS, New Delhi, India.
Highest degree:M.Sc. in Biotechnology
Major Subjects:Biotechnology [Molecular Biology, Immunology,Cell biology,
Biochemistry, Biostats……]
Projects/Research:Biophysical Chemistry
Scholarships:1. Have been awarded in the All India Biotechnology Quiz
Competition held at the ‘Centre for Biotechnology ‚ JNU, New Delhi, on the ‘National Science Day‘ 2003.
2. Awarded with Junior Research Fellowship (JRF) by Department of Biotectnology (DBT-JRF, 2005) India, and Indian council of Medical Research (ICMR-JRF,2005) ,India.
3. Lecturership by CSIR, India.
Scientific Interests and Goals:My main field of interest is Cell Biology and Biophysics, and
would be fortunate if could get an opportunity to explore and contribute to the better understanding of the field of Neurosciences and neurodegenarative disorders….
Hobbies and other interests:Music, Instrumental Music (Tabla, Piano, Bongo,… .), Sketching,
Painting, Adventure Sports….etc.
First Name:Kshama
Last Name:Gupta
Date of birth:22.06.1982
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. D. MansteinBiophysical Chemistry
EducationCollege/University:Masters in Biotechnology, University of Madras, 2002-2004.
Highest degree:Masters in Biotechnology
Major Subjects:Biotechnology, Biochemisty
Projects/Research:1. To generate a functional mouse model with a human
immune system and human liver cells for the study of HCV pathogenesis and therapy..
2. To study the functional ability of bone marrow derived stem cells in the repair of endothelial cell damage in liver.
Awards & Scholarships:1. Secured University 7th Rank– Masters Biotechnology 2002-
2004, University of Madras.2. Secured Overall Proficiency First Prize (Best outgoing
student 2004), Alpha Arts and Science College (University of Madras)
3. Junior Research Fellowship (JRF) from Indian Institute of Science, Bangalore, India.
Scientific Interests and Goals:My objective is to take up a challenging research and development position in the fields of stem cell biology, virology and contribute significantly to explore and discover the unseen leading to both human welfare and personal excellence.
Hobbies and other interests:Books, music, chess & cooking
First name:Dhivya
Last name:Haridass
Date of birth:17.07.1981
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. M. OttGastroenterology, Hepatology& Endocrinology
EducationCollege/University:1998 - 2004 University of Kaiserslautern (Germany)Diploma in Biology in January 2005Title of Thesis: „Analysis of conditional mdr-1 expression in human cells“ Diploma work done at the European Institute for research and development of transplantation strategies (EUFETS, FreseniusBiotech Group)
Major Subjects:Retroviral vectors, haematopoietic stem cell biology
Projects/Research:1) Evaluation and optimisation of „All-in-One“ retroviral vectorsbased on the Tetracycline-regulatory System2) Tet-regulated expression of HoxB4 in haematopoietic (stem) cells3) Tet-regulated expression of chemoresistance genes (MGMT/Mdr-1) in haematopoietic cells
Scientific Interests and Goals:The main interest of my work is to establish an optimized conditional gene expression system which is therapeutically applicable in the field of somatic gene therapy.
Hobbies and other interests:Meeting with friends, music, billard, card-games, soccer,
First name:Niels
Last name:Heinz
Date of birth:07.02.1978
Country:Germany
E-mail:[email protected]
Supervisor:Dr. B. SchiedlmeierProf. Dr. C. Baum Experimental Hematology
EducationUniversity:1997-2003 University Hamburg2000-2003 Medical thesis in the Inst.for Immunology, Hamburg2003-2004 University Lübeck: M.D.-degree2004-2006 Specialist training in neurology, Bad Segeberg
Highest degree:M.D.
Major Subjects:Immunology
Projects/Research:Silencing alloreactivity by leukaemia-specific T cell receptor(TCR) gene transfer
Awards:Second poster-price in the 5th Joint Meeting of theSignal Transduction Society (STS), Weimar 2001
Scientific Interests and Goals:My main field of interest is tumor immunology. In my project TCR gene
transfer into either autologous or allogeneic T cells shall be used to direct T cells specifically against leukemia associated antigens. The potential of genetically engineered T cells to either overcome endogenous tolerance against leukaemia-associated antigens or to break alloreactivity respectively shall be investigated
Hobbies and other interests:Playing the mouthorgan, out door activities
Publications:Krebs C., Koestner, W., Nissen M., Welge V., Parusel I., Malavasi F., Leiter E., H.
Santella R., M., Haag, F., Koch-Nolte F. Flow cytometric and immunoblotassays for cell surface ADP-ribosylation using a monoclonal antibody specificfor ethenoadenosine. Analytical Biochemistry 2003, 314(1):108-15.
Krebs C, Adriouch S, Braasch F, Koestner W, Leiter EH, Seman M, Lund FE, Oppenheimer N, Haag F, Koch-Nolte F. CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins. J Immunol. 2005;174(6):3298-305.
First name:Wolfgang
Last name:Koestner
Date of birth:10.06.1976
Country:Germany
E-mail:[email protected]
Supervisor:PD Dr. M. SauerPediatrics
EducationCollege/University:2004-2006 University of Pune, Pune MSc in Biotechnology.
Highest degree:MSc in Biotechnology
Major Subjects:Biotechnology
Projects/Research:Clinical Immunology, C5a pathway
Scholarships:1. DBT,Govt. of India Scholarship for All india combined M.Sc. biotechnology programe (2004-2006).2. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India, 2006.3. Junior Research Fellowship by DBT, Govt. of India, 2006.
Scientific Interests and Goals:My main field of interest is Immunology, which has clinicalapplication too!
Hobbies and other interests:Music, Net Surfing, literature, etc.
First name:Snehlata
Last name:Kumari
Date of birth:02.02.1981
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. J.E. GessnerClinical Immunology
EducationCollege/University:2000-2005 Ruhr-University Bochum, Germany
Highest degree:Diploma in Biology
Major Subjects:Molecular Biology and Virology
Projects/Research:1. Comparative studies of malignant transformation events caused
by gene transfer into hematopoietic stem cells by γ-retro andlentiviral vectors.
2. Identification of stem cell expanding genes by insertionalmutagenesis.
3. Improvement of gene transfer vectors and methods to increasegene therapy savety.
Scholarships:1. Awarded by „Studienstiftung des deutschen Volkes“ for
undergraduate studies (2003 – 2005)2. Awarded by „Studienstiftung des deutschen Volkes“ for
graduate studies (2006)
Scientific Interests and Goals:Retrovirus mediated gene therapy is one of the most interesting topics in science. It combines interdisciplinary research dealing with virology, signaling, imaging and all kinds of molecular biology at the boarder between life science and the clinics.One of my greatest scientific goals is to help make gene therapymore applicable and even saver than it is today, so that genetictreatment can become a standard therapy one day.
Hobbies and other interests:Music, Movies, Cocking, etc.
First name:Tobias
Last name:Mätzig
Date of birth:07.08.1979
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. C. BaumExperimental Hematology
EducationCollege/University:2004-2006 Madurai Kamaraj University, M.Sc. (MGT). 2001-2004 Presidency College, Bangalore University, B.Sc. in Biotechnology.
Highest degree:M.Sc. in Microbial Gene Technology
Major Subjects:Microbial Gene Technology
Projects/Research:Biochemistry
Scholarships:1. Junior Research Fellowship (JRF) awarded by Council forScientific and Industrial Research (CSIR), India.2. Bharat Petroleum Scholarship (2004) for higher studiesawarded by Bharat Petroleum Corporation, India.
Scientific Interests and Goals:My main field of interest is Biochemistry. I am interested in understanding the molecular basis of life. I have always tried and will always try to bring the branches of chemistry and biology together and see life as a set of co ordinated chemical events. I would like to add on to this basic understanding, which can makethings simple and life easier
Hobbies and other interests:Music, Reading, sketching etc.
First name:Manoj
Last name:BalakrishnaMenon
Date of birth:05.10.1983
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. M. GaestelPhysiological Chemistry
EducationCollege/University:2001-2004 : B.Sc. (Hons) Microbiology, University of Delhi,
India.2004-2006 : M.Sc. Biotechnology, A.I.I.M.S, New Delhi, India.
Highest degree:Masters in Biotechnology
Major Subjects:Biotechnology, Molecular Biology, Immunology and Cell biology
Projects/Research:•To study the effect of human MSC on engraftment and repopulation of cord blood derived haematopoietic stem cells in sublethaly irradiated Balb/C Rag2/yc(-/-) mice.•To study in vitro the differentiation of hMSC to hepatocytes.
Scholarships/Awards:Awarded Junior Research Fellowship by Indian Council of Medical Research (I.C.M.R) in Jul 2006Awarded lectureship in NET-CSIR Examination held in Dec 2005Awarded Junior Research Fellowship by Indian council for Agricultural Research in 2004.Received the award for “Best student in microbial World” in graduation.
Scientific Interests and Goals:My main field of interest is Stem Cell Biology.The role of the stem cells in giving rise to different cell types and entire organs for tissue repair and transplants, is what fascinates me the most. I welcome the challenge of serving global community by participating in such a dynamic and challenging field as that ofstem cell liver transplantation. I would consider myself flourishing in my endeavors if I am able to make a sound and humble contribution towards the betterment of patients suffering from liver injuries and failures.
Hobbies and other interests:Traveling to different places,listening to music, dancing and watching movies.
Publications:V. Baniasadi, N. Narain, R. Goswami & S.N. Das. Promoter region –318 C/T and –1661 A/G CTLA-4 Single nucleotide polymorphisms and type 1 diabetes in North Indians. Tissue antigens 2006 : 67 : 383-389.
First name:Nidhi
Last name:Narain
Date of birth:26.07.1983
Country:India
E-mail:nidhinarain@@yahoo.com
Supervisor:Prof. Dr. M. OttGastroenterolgy, Hepatology & Endocrinology
Education2001-2006 University of Hanover, Germany
Highest degree:Diploma‘ in Biology
Subjects:Cellular and Developmental BiologyBiochemistryImmunology
Projects/Research:1. Membrane association and sorting of splicing variants and
artificially generated mutants of intestinal lactase2. Protein – Protein and Protein-DNA interactions at the DNA
replication fork of E.coli
Scientific Interests and Goals:It’s interesting how proteins work, so I am fortunate that my PhD project involves comparison of protein structure and function.
Hobbies and other interests:English Literature, Travel, Botany
First name:Natalie
Last name:Naue
Date of birth:14.04.1982
Country:Germany
E-mail:[email protected]
Supervisor:Dr. U. CurthBiophysical Chemistry
EducationCollege/University:2000-2006 Medizinische Hochschule Hannover, Medicine
Highest degree:MD
Major Subjects:Transplantation Medicine
Projects/Research:1. In vitro studies of the natural killer cell complex: intra- and intercellular response to ligands2. In vivo experiments: the role of the natural killer cell complex in transplantation
Scientific Interests and Goals:Transplantation immunology is of most interest to me. Although there are great progresses done on this field of research a lot of pathomechanisms leading to graft loss or acceptance are still not known yet. It is my effort to gain a deeper insight of those mechanisms and to transfer this knowledge to clinical practice.
Hobbies and other interests:music, sports, movies, literature, etc.
Publications:Koch M., Mengel M., Poehnert D., Nashan B.: Effects of Everolimus on cellular and humoral immune processes leading to CAN in a rat model with sensitized recipients; accepted in Transplantation
First name:Poehnert
Last name:Daniel
Date of birth:25.04.1981
Country:Germany
E-mail:[email protected]
Supervisor:Dr. M. Koch/ PD Dr. R. LückVisceral Surgery
Education University:2001-2006 Universität Hannover
Highest degree:Diplom-Biologe
Major Subjects:Biophysics
Projects/Research:Motor Mechanics of Cytoplasmic Dynein
Scientific Interests and Goals:Molecular motors like cytoplasmic dynein are the heart of almost all biological transport processes, whether in organized structures, such as in muscles and axonemes or acting in isolation to move single sub-micron-sized cargo. There are many diseases linked to mutations in molecular motors and understanding of the molecular interaction during the force-generating cycle is still at an elementary stage. That is why I will try to find out more about cytoplasmic dynein's motor mechanics.
Hobbies and other interests:Music and instruments, canoeing, literature,photos
First name:Walter
Last name:Wilhelm
Date of birth:04.04.1982
Country:Austria
E-mail:[email protected]
Supervisor:PD Dr. W. SteffenMolecular and Cell Physiology
EducationCollege/University:2000-2005 Carl von Ossietzky University, Oldenburg
Highest degree:Dipl. Biology
Major Subjects:Molecular Biology
Projects/Research:1. Mechanisms of cell and isotype specific Gαi dependent
signaling pathways in immune effector cells2. Inhibition of the NFκB repressing factor (NRF) mRNA by
RNA-Interference3. Age determination of Orix euplectes by the length of
telomeres
Scholarships:GRK 705 II „ Characterization of pathophysiological
animal models“, Medical School Hanover
Scientific Interests and Goals:My main field of interest is gene regulation and
signaltransduction in the immune system. I would like to understand some of the complex mechanism which providethe basis for the diverse organisation of the immune system.
Hobbies and other interests:Scuba Diving, Photography, Motorbike
First name:Kristina
Last name:Wiege
Date of birth:14.12.1977
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. J.E. GessnerClinical Immunology
EducationCollege/University:2001-2004 Peking Union Medical College, P.R. China
Highest degree:M.Sc. In Molecular Immunology
Major Subjects:Immunology, Medicine
Projects/Research:1.Identification of alternative spliced isoforms of hIL-23R2.The role of IFN gamma on tumor stroma cells3.The role of stroma cells (including mesenchymal stem cells) in the
functional organization of lymphoid organs
Scholarships:Medical Education Scholarship of The United Laboratories (Hongkong) in the Medical Universities of mainland China, Golden Prize (1998-1999)
Scientific interests and goals:Immune system is quite fancy, finding something novel and interesting in basic immunological areas is my long term goal. My scientific goal during Ph.D study is to identify something new on stroma cells of lymphoid organs, e.g. what’s the special subset marker, how they function on the interactions of different immune cells especially their migration during the development of lymphoid organs and immune reactions. Besides this I also quite like transcriptional and epigenetics control of lymphocytes, in their functional differentiation and memory, etc.
Hobbies and other interests:Hiking, Music, Reading
Publication List:Xiangyue Zhang, Shuhui Wang. Progress in the study of IL-23 and IL-23 receptor,BasicMedical Sciences and Clinics,August, 2004; 24(4), p457-461.
Xiangyue Zhang, Zhiguang Li, Zhihai Qin. Cancer Immunosurveillance or not? (New view), Progress in biochemistry and biophysics, November,
2005;32(11), p1093-1098.
Xiangyue Zhang, Li Liu, et al. Alternative Splicing of Human IL-23 Receptor Gene Generates Multiple Isoforms in Selected Tumor Cell Lines. Immunogenetics, 2006 Jan;57(12):934-43
First name:Xiangyue
Last name:Zhang
Date of birth:24.10.1978
Country:P. R. China
E-mail:[email protected]
Supervisor:Prof. Dr. R. FörsterImmunology
Faculty Jürgen Alves Andreas Lengeling (GBF)
Christopher Baum Zhixiong Li
Armin Braun (Fraunhofer Inst.itut) Robert Lindner
Jan Buer (GBF) Nisar Peter Malek
Olaf Dammann Dietmar Manstein
Matthias Eder Ulrich Maus
Britta Eiz-Vesper Fritz Melchers (MPI, Berlin)
Reinhold Förster Martin Messerle
Matthias Gaestel Nils v. Neuhoff
Harald Genth Heiner Niemann (TiHo, Mariensee)
Engelbert Gessner Francoise Routier
Achim Gossler Lenhard Rudolph
David Groneberg Michaela Scherr
Matthias Gunzer (GBF) Bernhard Schieffer
Carlos Alberto Guzmann (GBF) Brigitte Schlegelberger
Hermann Haller Reinhold Ernst Schmidt
Hansjörg Hauser (GBF) Jörg Schmidtke
Hans Heiken Thomas F. Schulz
Denise Hilfiker Reinhard Schwinzer
Helmut Holtmann Ursula Seidler
Peter Horn Axel Seltsam
Roland Jacobs Beate Sodeik
Elmar Jaeckel Manfred Stuhrmann-Spangenberg
Christine Josenhans Burkhard Tümmler
Ingo Just Ernst Ungewickell
Andreas Kispert Claus Urbanke
Christoph Klein Jürgen Wehland (GBF)
Andreas Klos Siegfried Weiss (GBF)
Hannes Klump Eva Weissinger
Alexey Kotlyarov Karl H. Welte
Hans Kreipe Thomas Werfel
Norbert Krug (Fraunhofer Institut) Miriam Wittmann
Ulrich Lehmann Anna M. Wobus (IPK Gatersleben)
Department and function:Professor, Biophysical Chemistry
Education:1975 – 1981 University of Hannover, Biochemistry1981 – 1984 PhD thesis
Positions:1984 – 1990 Postdoc Hannover Medical School1990 – 1995 PD Hannover Medical School1995 - Prof. Hannover Medical School
Major research interests:Protein design using different model systems:• Restriction endonuclease EcoRI• IS1 Transposase• Helikase I• DynaminCircular Dichroism Spectroscopy
Selected Publications:Kalthoff C, Alves J, Urbanke C, Knorr R, Ungewickell EJ. J Biol Chem 2002, 277: 8209-16.Scheele U, Alves J, Frank R, Duwel M, Kalthoff C, Ungewickell E. J Biol Chem. 2003; 278(28):25357-68.Fritsche P, Alves J. Biol Chem. 2004; 385(10):975-85Wierstra I, Alves J. Biochem Biophys Res Commun. 2006 Sep 15;348(1):99-108.Wierstra I, Alves J. Biol Chem. 2006 Jul;387(7):949-62. Wierstra I, Alves J. Biol Chem. 2006 Jul;387(7):963-76.Wierstra I, Alves J. FEBS J. 2006 Oct;273(20):4645-67Wierstra I, Alves J. Biochem Biophys Res Commun. 2007;352(1):61-8.
First name:Jürgen
Last name:Alves
Acad. Title:Prof. Dr. rer. nat.
Address:OE 4350Hannover Medical School
Phone and e-mail:++49-0511-532 [email protected]
Further information:http://www.mh-hannover.de/institute/bpc
Department and function:Professor, Experimental Hematology
Education:1981-1982 Philosophy1982-1989 Medicine
Positions:1989-1991 Research Clinics, Borstel b. Bad Oldesloe1991-1992 Toxicology, Univ. of Hamburg1993-1999 Heinrich-Pette-Institute Hamburg 2000 University Hospital Eppendorf, Hamburg2000 - MHH, Dept. Hematology and Oncology2002 - Cincinnati Children‘s Hospital Adjunct Position2006 - Head of Experimental Hematology
Major research interests:Cell Therapy, Gene Transfer and TherapyRetroviruses, Gene expressionStem Cell BiologyBiology of cell selection and clonal evolutionOncogenesis
Selected Publications:Baum C, et al. Mol Ther. 2004; 9(1):5-13.Werner M, et al. Gene Ther. 2004; 11(12):992-1000Klein C, Baum C. Hematol J. 2004;5(2):103-11Williams D, Baum C Nature. 2004; 429(6988):129Frank O, et al. Blood. 2004; 104(12):3543-9.Kraunus J, et al. Gene Ther. 2004; 11(21):1568-78.Galla M, et al. Mol Cell. 2004; 16(2):309-15. von Kalle C, et al. Semin Hematol. 2004; 41(4):303-18.Modlich U, et al. Blood. 2005; 105(11):4235-46.Kustikova O, et al. Science. 2005; 308(5725):1171-4.Klump H, et al. Ann N Y Acad Sci. 2005; 1044:6-15.Schambach A, et al. Mol Ther. 2006 Feb;13(2):391-400.Schambach A, et al. Gene Ther. 2006; Apr;13(7):641-5Schambach A, et al. Gene Ther. 2006 Jul;13(13):1037-47Schambach A, et al. Exp Hematol. 2006 May;34(5):588-92.Modlich U, et al. Blood. 2006 Oct 15;108(8):2545-53.Kraunus J, et al. J Biol Chem. 2006 Dec 8;281(49):37381-90Kustikova OS, et al. Blood. 2006 Nov 21; E pub
First name:Christopher
Last name:Baum
Acad. Title:Prof. Dr. med.Prof. of Pediatrics
Address:OE 6960Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www99.mh-hannover.de/kliniken/zellth/
Department and function:Head of Immunology and Allergology, Fraunhofer Institute of Toxicology and Experimental Medicine
Education:1998 PhD in Immunology, Humboldt-University
Berlin
Positions:1999-2001 Scientific Assistant (“post doc”), Prof. Dr. Renz,
Department of Clinical Chemistry, Philipps University Marburg, Germany
2001- Head of Immunology and Allergology, FraunhoferInstitute of Toxicology and Experimental Medicine
Major research interests:Neuro-immun Interaction in asthmaAnimal models of asthmaLung infection modelsImmunotoxicology
Selected Publications:C. Nassenstein, A. Braun, V.J. Erpenbeck, M. Lommatzsch, et al. J Exp Med. 2003; 198:455-467.A. Braun, M. Lommatzsch, U. Neuhaus-Steinmetz, D. Quarcoo, H. Renz. Br J Pharmacol. 2004;141:431-440H. Weigt, P.F. Muhlradt, M. Larbig, N. Krug, A. Braun. J Immunol. 2004; 172(10):6080-6.U. Forssmann, I. Hartung, R. Bälder, S.E. Escher, et al. J Immunol. 2004; 173(5):3456-66..R. Bälder, B. Fuchs, W. Bautsch, J. Zwirner, et al. J. Immunol. 2005; 174(2):783-9.Schulte-Herbruggen O, Nassenstein C, Lommatzsch M, Quarcoo D, Renz H, Braun A. J Neuroimmunol. 2005;160(1-2):204-9Weigt H, Nassenstein C, Tschernig T, Muhlradt PF, Krug N, Braun A. Am J RespirCrit Care Med. 2005;172(5):566-72.Lommatzsch M, Quarcoo D, Schulte-Herbruggen O, Weber H, Virchow JC, Renz H, Braun A. Int J Dev Neurosci. 2005;23(6):495-500.Nassenstein C, Schulte-Herbruggen O, Renz H, Braun A. Eur J Pharmacol. 2006; 533(1-3):195-206. Nassenstein C, Dawbarn D, Pollock K, Allen SJ, Erpenbeck VJ, Spies E, Krug N, Braun A. J Allergy Clin Immunol. 2006;118(3):597-605
First name:Armin
Last name:Braun
Acad. Title:PD Dr.
Address:Nikolai-Fuchs-Str. 130625 Hannover
Phone and e-mail:+49 511 5350 [email protected]
Further information:www.item.fraunhofer.de
Department and function:Professor, Mucosal Immunity, HZI Braunschweig
Education:1987-1994 Medicine in Hannover and New York, 1995 Approbation, Doctor of Medicine, 2001 Habilitation in Immunology,
Positions:1998-present Head of Mucosal Immunity (HZI), 1998-present Institute of Medical Microbiology (MHH), 1996-1998 DFG-Fellowship in Immunology, Hôpital Necker-
Enfants Malades, Paris, France,1995-1996 Resident in Internal Medicine, Department of
Hematology and Oncology (MHH),
Major research interests:My current work on mucosal immunity concentrates on functional genomics of regulatory T cells in transgenic mouse models and patients with autoimmunity and inflammation. Other interests are Host-Pathogen-Crosstalk and Molecular Diagnostics.
Selected Publications:Bruder D, Westendorf AM, Geffers R, Gruber AD, et al. Am J Respir Crit Care Med. 2004; 170(11):1145-52Westendorf AM, Templin M, Geffers R, Deppenmeier S, et al. Gut. 2005; 54:60-9.Ma HW, Kumar B, Ditges U, Gunzer F, Buer J, Zeng AP. Nucleic Acids Res. 2004; 32(22):6643-9.Juhas M, Wiehlmann L, Salunkhe P, Lauber J, Buer J, Tummler B. FEMS MicrobiolLett. 2005; 242(2):287-95Rharbaoui F, Bruder D, Vidakovic M, Ebensen T, Buer J, Guzman CA. J Immunol. 2005; 174(3):1317-24Bruder D, Westendorf AM, Hansen W, Prettin S, Gruber AD, Qian Y, von BoehmerH, Mahnke K, Buer J. Diabetes. 2005;54(12):3395-401.Hansen W, Loser K, Westendorf AM, Bruder D, Pfoertner S, Siewert C, Huehn J, Beissert S, Buer J. J Immunol. 2006;177(1):209-15.Franzke A, Hunger JK, Dittmar KE, Ganser A, Buer J. Ann Hematol. 2006;85(11):747-58. Westendorf AM, Fleissner D, Deppenmeier S, Gruber AD, Bruder D, Hansen W, Liblau R, Buer J.Gastroenterology. 2006;131(2):510-24.Franzke A, Koenecke C, Geffers R, Piao W, Hunger JK, Ganser A, Buer J. TumourBiol. 2006;27(6):329-33.Westendorf AM, Bruder D, Hansen W, Buer J. Ann N Y Acad Sci. 2006;1072:401-6.
First name:Jan
Last name:Buer
Acad. Title:Prof. Dr. med.
Address:HZIMascheroder Weg 138124 Braunschweig
Phone and e-mail:[email protected]
Further information:www.helmholtz-hzi.de
Department and function:Head, Perinatal Infectious Disease Epidemiology UnitObstetrics, Prenatal Medicine, and General GynecologyPediatric Pulmonology and Neonatology
Education:1981-83 Linguistics, U of Hamburg, 1983-90 Medicine, Med U of Lübeck and U of Hamburg,
Epidemiology,1996-97 Harvard School of Public Health,
Positions:1991-95 Post-Doc, Pediatrics, U of Hamburg1995-97 Post-Doc, Neuroepidemiology, Children‘s Hospital,
Boston,1997-2000 Instructor in Neurology, Harvard Med School,since 2000 Assistant Professor in Neurology, Harvard Med School, since 2002 Professor of Perinatal Infectiology, Hannover Med.
School
Major research interests:Epidemiologic research on the role of infection and inflammation in theetiology and pathogenesis of brain white matter damage in pretermnewborns
Selected Publications:Dammann O, Leviton A. Ann Neurol. 2004;55(2):158-161.Dammann O, Allred EN, Van Marter LJ, Dammann CE, Leviton A. Pediatr Res. 2004; 55(2):319-325.Leviton A, Dammann O. Pediatr Res. 2004; 55(4):541-5Losch H, Dammann O. J Child Neurol. 2004; 19(5):318-22.Dammann O, Allred EN, Leviton A, Shen-Schwarz S, Heller D, Genest DR, Collins MH. Placenta. 2004; 25(10):788-96.Dammann O, Bartels DB, Berner R. Pediatr Infect Dis J. 2004;23(10):978-9Bartels DB, Kreienbrock L, Dammann O, Wenzlaff P, Poets CF. Arch Dis Child FetalNeonatal Ed. 2005; 90(1):F53-9.Leviton A, Blair E, Dammann O, Allred E. J Pediatr. 2005; 146(1):123-7.Dammann O, Leviton A, Gappa M, Dammann CE. BJOG. 2005 Mar;112 Suppl 1:4-9.Dammann O, Hori A, Szentiks C, Hewicker-Trautwein M. Dev Med Child Neurol. 2006; 48(4):290-3.Dammann O, Leviton A. Semin Fetal Neonatal Med. 2006 Oct;11(5):363-8.Dammann O, Leviton A. N Engl J Med. 2006 Aug 17;355(7):727-9.Dordelmann M, Kerk J, Dressler F, Brinkhaus MJ, Bartels DB, Dammann CE, Dork T, Dammann O. Neuropediatrics. 2006 Jun;37(3):130-6.
First name:Olaf
Last name:Dammann
Acad. Title:Prof. Dr.med., M.Sc.
Address:OE6415Hannover Medical School
Phone and e-mail:++49-511- 532 [email protected]
Further information:http://www.mh-hannover.de/forschung/perinatalinfektiologie/index.htm
Department and function:Professor, Hematology/Oncology unit; Consultant Bone marrow transplantation
Education:1982-89 Study of Medicine, Homburg/S and
Frankfurt/M1990 Doctoral thesis1989-91 Research assistant and fellow Int. Med.1991-93 Research fellow Dana Farber Cancer Inst., Boston1993-2000 Research fellow Int. Med. Frankfurt + MHHSince 2001 Habilitation, consultant Int. Medicine
Positions:1991-1993 Dana Farber Cancer Institute, Boston1993-1996 Johann Wolfgang v.Goethe University
FrankfurtSince 1996 MHH
Major research interests:Signal transduction by cytokine receptors in myeloid cellsModels for myeloproliferative disorders and acuteleukemiaLentiviral gene transferRNA interference
Selected Publications:Scherr M, Battmer K, Winkler T, Heidenreich O, Ganser A, Eder M.. Blood 2003, 101:1566Scherr M, Morgan MA, Eder M. Curr Med.Chem 2003, 10: 245Tiede A, Eder M, von Depka M, Battmer K, Luther S, et al. Gene Ther. 2003; 10(22):1917-25. Scherr M, Steinmann D, Eder M. Ann Hematol. 2004; 83(1):1-8.Scherr M, Battmer K, Dallmann I, Ganser A, Eder M. Oligonucleotides. 2003; 13(5):353-63.Scherr M, Eder M. Curr Opin Mol Ther. 2004; 6(2):129-35Scherr M, Battmer K, Schultheis B, Ganser A, Eder M. Gene Ther. 2005; 12:12-21.Eder M, Scherr M. N Engl J Med. 2005; 352(23):2446-8.Scherr M, Chaturvedi A, Battmer K, Dallmann I, Schultheis B, Ganser A, Eder M. Blood. 2006;107(8):3279-87.Venturini L, Eder M, Scherr M. J Biomed Biotechnol. 2006;2006(4):87340.Venturini L, Battmer K, Castoldi M, Schultheis B, Hochhaus A, Muckenthaler MU, Ganser A, Eder M, Scherr M. Blood. 2007 Feb 6; [Epub ahead of print]
First name:Matthias
Last name:Eder
Acad. Title:Prof. Dr. med.
Address:OE 6860Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/kliniken/haemonko/index.htm
Department and function:Professor, Institute for Transfusion Medicine
Education:1988 – 1993 Biology, University Greifswald1993 – 1996 PhD, Virology, MHH2003 W1-Professor for Immunogenetics, Institute for
Transfusion Medicine, MHH
Positions:1996-1999 Research Group Leader at the German Red Cross
Institute, Springe1999-2003 Research Group Leader, Institute for Transfusion
Medicine, MHH2003-recent W1-Professor for Immunogenetics, Institute for
Transfusion Medicine, MHH
Major research interests:• Minor histocompatibility antigens involved in GvL and GvHD• Antigen-specific cytotoxic T cells• Cell therapy• Expression of recombinant HLAs and proteins• Peptide sequencing
Selected Publications:Elsner HA, Bernard G, Eiz-Vesper B, de Matteis M, Bernard A, Blasczyk R. Tissue
Antigens. 2002; 59(2):139-141.Khattab B, Eiz-Vesper B, Ganser A, Hertenstein B, Blasczyk R. Ann Hematol 2004:
83: 107-113.Eiz-Vesper B, Seltsam A, Blasczyk R. Transfusion 2005; 45 (6): 960-968.Bade-Doeding C, Elsner HA, Eiz-Vesper B, Seltsam A, Holtkamp U, Blasczyk R.
Immunogenetics 2004; 56: 83 - 88. Bade-Doeding C, Elsner HA, Eiz-Vesper B, Seltsam A, Holtkamp U, Blasczyk R.
Immunogenetics 2005; 56: 769-772.Eiz-Vesper B, Horn PA, Daubert C, Khattab B, Blasczyk R. Transfusion 2006;
46(7):1210-20.Bade-Doeding C, Deluca DS, Seltsam A, Blasczyk R, Eiz-Vesper B. Immunogenetics
2007 Feb 10; [Epub ahead of print]
First name:Britta
Last name:Eiz-Vesper
Acad. Title:Prof. Dr. rer. nat.
Address:OE 8355Institute for Transfusion MedicineHannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/transfusion
Department and function:Director, Immunology
Education:1981 Abitur, Gymnasium Pegnitz1988 DVM, Munich, Veterinary Faculty1988 - 1991 Ph.D. Thesis
Positions:1991-93 Postdoc, Insitute of Biochemistry, University of Munich1994-00 Research Associate, Max-Delbruck-Center for
Molecular Medicine, Berlin2000-01 Associate Professor for Experimental Surgery and
Immunology, University of Erlangen2001 – Director and Head, Institute of Imunology, Professor for
Immunology
Major research interests:Chemokines and chemokine receptors, role in lymphoid organorganogenesis and organization, development of immunology memory,cell migration, tumor metastasis
Selected Publications:Pabst O, Ohl L, Wendland M, Wurbel MA, Kremmer E, Malissen B, Forster R J Exp
Med. 2004; 199(3):411-6Pabst O, Herbrand H, Bernhardt G, Forster R. Curr Opin Immunol. 2004; 16:394-9.Misslitz A, Pabst O, Hintzen G, Ohl L, et al. J Exp Med. 2004; 200(4):481-91Ohl L, Mohaupt M, Czeloth N, Hintzen G, et al. Immunity. 2004; 21(2):279-88.Pabst O, Herbrand H, Worbs T, Friedrichsen M, et al. Eur J Immunol. 2005; 35:98-
107.Gunther K, Leier J, Henning G, Dimmler A, Weissbach R, Hohenberger W, Forster
R. Int J Cancer. 2005 Sep 20;116(5):726-33Hardtke S, Ohl L, Forster R. Blood. 2005 Sep 15;106(6):1924-31.Pabst O, Peters T, Czeloth N, Bernhardt G, Scharffetter-Kochanek K, Forster R. J
Immunol. 2005 Jun 15;174(12):7492-5.Czeloth N, Bernhardt G, Hofmann F, Genth H, Forster R. J Immunol. 2005;
175(5):2960-7.Pabst O, Herbrand H, Willenzon S, Worbs T, Schippers A, Muller W, Bernhardt G,
Forster R. J Immunol. 2006; 176(3):1474-80.Pabst O, Herbrand H, Friedrichsen M, Velaga S, Dorsch M, Berhardt G, Worbs T, Macpherson AJ, Forster R. J Immunol. 2006 Nov 15;177(10):6824-32.Hintzen G, Ohl L, del Rio ML, Rodriguez-Barbosa JI, Pabst O, Kocks JR, Krege J, Hardtke S, Forster R. J Immunol. 2006 Nov 15;177(10):7346-54.Berberich S, Forster R, Pabst O. Blood. 2007 Feb 8; [Epub ahead of print] Davalos-Misslitz AC, Rieckenberg J, Willenzon S, Worbs T, Kremmer E, Bernhardt G, Forster R. Eur J Immunol. 2007 Feb 16; [Epub ahead of print]
First name:Reinhold
Last name:Förster
Acad. Title:Prof. Dr. med. vet
Address:OE5240Hannover Medical School
Phone and e-mail:[email protected]
Department and function:Director, Biochemistry (Physiological Chemistry)
Education:1983 PhD in Biology (Biophysics), Humboldt-University
Berlin1993 Habilitation in Biochemistry, Free University Berlin
Positions:1991-1995: Junior Research Group Leader at the Max-Delbrück-
Centrum for Molecular Medicine (MDC), Berlin-Buch1995-1997: Heisenberg-Fellow of the German Research Council
(DFG), Guest Research Group Leader at the MDC,Berlin-Buch
1997-2000: Professor of Molecular Genetics; Innovationskolleg"Zellspezialisierung" of the Martin-Luther-UniversityHalle-Wittenberg
2001-recent: Chair and Head of Institute of Biochemistry/ Physiological Chemistry of Hannover Medical School
Major research interests:Analysis of mechanisms of stress-dependent signal transductionNucleo-cytoplasmic signallingRegulation of gene expression by protein phosphorylation at the post-transcriptional level
Selected Publications:Neininger A., Thielemann H, Gaestel M. EMBO Rep. 2001; 2: 703-708.Neininger A., Kontoyiannis D., Kotlyarov A., Winzen R., Eckert R., et al. J. Biol. Chem. 2002; 277: 3065-3068.Kotlyarov A., Yannoni Y., Fritz S., Laaß K., Telliez J.-B., et al. Mol. Cell. Biol. 2002; 22: 4827-4835.Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, et al. Mol Cell Biol. 2003; 23(21): 7732-7741.Schumacher S, Laass K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, Gaestel M EMBO J. 2004; 23(24):4770-4779Gaestel M. Nat Rev Mol Cell Biol. 2006; 7(2):120-30.Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Mol Cell Biol. 2006;26(6):2399-407.Vertii A, Hakim C, Kotlyarov A, Gaestel M. J Biol Chem. 2006;281(37):26966-75Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M. J Biol Chem. 2006;281(46):35511-9.
First name:Matthias
Last name:Gaestel
Acad. Title:Prof. Dr.
Address:OE 4310Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/biochemie
Department and function:Group leader, Department of Toxicology
Education:1998-95 Chemistry, Technical University of Darmstadt,
Germany 1995-2000 PhD in Chemistry, Albert-Ludwigs-Universität
Freiburg
Positions:2000-recent: Group leader, Institute of Toxicology/
Hannover Medical School
Major research interests:Mode of action of bacterial protein toxinsSignal transduction pathways governed by Rho and Ras
Selected Publications:Genth, H., J. Selzer, C. Busch, J. Dumbach, F. Hofmann, K. Aktories, I. Just.. Infection and Immunity. 2000; 68: 1094-1101Genth, H., R. Gerhard, A. Maeda, M. Amano, K. Kaibuchi, K. Aktories, I. Just.. Journal of Biological Chemistry. 2003; 278:28523-28527.Gerhard,R., H. Tatge, H. Genth, T. Thum, J. Borlak, G. Fritz, I. Just.. Journal of Biological Chemistry 2005; 280(2):1499-505, 2005.Czeloth, N., G. Bernhardt, F. Hofmann, H. Genth, R. Foerster. Journal of Immunology 2005; 175(5):2960-7.Genth H, Huelsenbeck J, Hartmann B, Hofmann F, Just I, Gerhard R. FEBS Lett. 2006;580(14):3565-9Huelsenbeck J, Dreger S, Gerhard R, Barth H, Just I, Genth H. Infect Immun. 2007;
75(2):801-9.
First name:Harald
Last name:Genth
Acad. Title:Dr. rer. nat.
Address:OE 5340Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/toxikologie
Department and function:Group Leader, Laboratory of Molecular Immunology; ClinicalImmunology
Education:1993 PhD in Chemistry and Molecular Biology, Technical
University (TU) Berlin1999 Habilitation in Immunology, Hannover Medical School
Positions:1994-1996: Research Associate, Dept. of Clinical Immunology,
Hannover Medical School 1994: Visiting Scientist, Dept. of Immunology, University of
Utrecht, The Netherlands1997: EMBO Research Fellow, Dept. of Pathology, CMU
Geneva, Switzerland1997-recent: Research Group Leader, and from 2002 on, Scientific
Director and Head of the Laboratory of Molecular Immunology at the Department of Clinical Immunology, Hannover Medical School
Major research interests:I) Analysis of molecular mechanisms underlying immunoregulationduring disease development in gene knockout mice.II) Signal transduction of G-protein coupled receptors.III) Gene regulation of IgG Fc receptors and their targeting for theestablishment of new therapeutic strategies.
Selected Publications:Schiller C. et al. Eur J Immunol. 2000; 30:481-490.Baumann U. et al. J Immunol. 2000; 164:1065-1070.Baumann U. et al. J Immunol. 2001; 167:1022-1027.Chouchakova N. et al. J Immunol. 2001; 166:5193-5200.Heusohn F. et al. J Immunol. 2002; 168:2857-2864.Radeke HH. et al. J Biol Chem. 2002; 277:27535-27544.Shushakova N. et al. J Clin Invest. 2002; 110:1823-1830.Nieswandt B. et al. Int Immunol. 2003; 15:341-349.Godau J, et al. J Immunol. 2004; 173(5):3437-45Skokowa J, et al. J Immunol. 2005; 174(5):3041-50.Wingender G, et al. Immunology. 2006; 117(1):117-26.Kumar V, et al. J Clin Invest. 2006;116(2):512-20.Konrad S, et al. Br J Haematol. 2006 Aug;134(3):345-7
First name:J. Engelbert
Last name:Geßner
Acad. Title:Prof. Dr. rer.nat.Dr. hum.biol.habil.
Address:OE 6830Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/immun
Department and function:Director, Molecular Biology
Education:1982 B.S. Eberhard-Karls-University, Tübingen,) 1983 M.S. Friedrich-Miescher-Laboratory (FML) of
the Max-Planck-Society, Tübingen1986 Ph.D. Max-Planck-Society, Tübingen1987 - 1989 Postdoc at the Mount Sinai Hospital Res.
Institute, Toronto, Canada
Positions:June 1989- July 1994 Head of an independent research group at
Max-Delbrück-Lab., Cologne, GermanyApril 1994 Habilitation: University of Cologne Aug. 1994 - July 1997 Associate Staff Scientist, The Jackson
Laboratory, Bar Harbor, MEAug. 1997 - June 1999 Staff Scientist , The Jackson Laboratorysince July 1999 Professor for Molecular Biology, MHH
Major research interests:The main research interest of the group lies on the analysis of the molecular mechanisms underlying developmental processes during mammalian embryogenesis. Development of the Notochord The notochord is a transient embryonic structure that serves as a signaling center that is essential for the dorsoventralpatterning of the spinal cord and somites. Various mutations in mice disturb the development or maintenance of the notochord. Identification and functional characterization of the genes affected by these mutations is the subject of several projects. Somitogenesis Somites form as the result of segmentation of the paraxial mesoderm. They give rise to the vertebrae, ribs, the epaxial and hypaxialmuscles and the dorsal dermis. Their formation lays the basis for the metameric arrangement of the vertebrae and of the spinal ganglia. The formation of segments as well as their subdivision into cranial and caudal compartments is the subject of our investigations. We analyse the role of Notch signalling in these processes as well as spontaneous mouse mutants in which somitogenesis is disrupted.
Selected Publications:Cordes R, Schuster-Gossler K, Serth K, Gossler A. Development. 2004; 131:1221-33Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A. Genes Dev. 2004; 18(10):1209-21.Abdelkhalek HB, Beckers A, Schuster-Gossler K, Pavlova MN, et al. Genes Dev. 2004; 18(14):1725-36Hofmann M, Schuster-Gossler K, Watabe-Rudolph M, Aulehla A, Herrmann BG, Gossler A. Genes Dev. 2004; 18(22):2712-7Schroder N, Sekhar A, Geffers I, Muller J, Dittrich-Breiholz O, Kracht M, Wedemeyer J, Gossler A. Gastroenterology. 2006;130(3):902-7.Schuster-Gossler K, Cordes R, Gossler A. Proc Natl Acad Sci U S A. 2007; 104(2):537-42.
First name:Achim
Last name:Gossler
Acad. Title:Prof. Dr.
Address:OE 5250Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/institute/molekularbiologie/
Department and function:Chair of Molecular Pneumology, Department of Respiratory Medicine
Education:2000 MD, Justus-Liebig-University, Giessen2004 Habilitation in Medicine, Free University Berlin
Positions:2000: Visiting Research Fellow (DAAD), National Heart and
Lung Institute, Imperial College, London, UK2000-2002: Clinical Research Fellow, Charité, Berlin2002-2003: Jun.-Professor of Respiratory Immunology and
Infectiology, Research Center Borstel and University of Lübeck
2003-2004: Senior Lecturer and head, Molecular Pneumology, Allergy Centre, Charité, Berlin
2004-2006: Assoc. Prof. (PD), later acting director, Institute of Occupational Medicine, Charité, Berlin
Since 2006: Prof. and Chair, Molecular Pneumology, Hannover Medical School
Major research interests:Neuroimmune mediators of inflammationPathophysiology of obstructive airway diseasesPathophysiology of occupational and environmental diseases
Selected Publications:Heppt W, Dinh QT, Cryer A, Zweng M, Noga O, Peiser C, Melvan M, Witt C, Fischer A, Groneberg DA. Clin Exp Allergy. 2004 Jul;34(7):1105-10.Groneberg DA, Niimi A, Dinh QT, Cosio B, Hew M, Fischer A, Chung KF. Am J Respir Crit Care Med. 2004 Dec 15;170(12):1276-80.Groneberg DA, Peiser C, Eynott PR, Welker P, Erbes R, Witt C, Chung KF, Fischer A. Biol Chem. 2005 Jan;386(1):53-9.Feleszko W, Zawadzka-Krajewska A, Matysiak K, Lewandowska D, Peradzynska J, Dinh QT, Hamelmann E, Groneberg DA, Kulus M. J Allergy Clin Immunol. 2006 Jan;117(1):97-102.Reviews:Groneberg DA, Fischer A, Chung KF, Daniel H. Am J Respir Cell Mol Biol. 2004 Mar;30(3):251-60.Groneberg DA, Poutanen SM, Low DE, Lode H, Welte T, Zabel P. Lancet Infect Dis. 2005 Mar;5(3):147-55.Groneberg DA, Rabe KF, Fischer A. Eur J Pharmacol. 2006 Mar 8;533(1-3):182-94. Groneberg DA, Harrison S, Dinh QT, Geppetti P, Fischer A. Curr Drug Targets. 2006 Aug;7(8):1005-10.
First name:David
Last name:Groneberg
Acad. Title:Prof. Dr.
Address:OE 6870Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/5534.html
Department and function:Head of Junior Research Group Immunodynamics, HZI
Education:1999 Diploma in Biochemistry, University of
Witten/Herdecke, Witten1999 PhD in Biology (Immunology), University of
Witten/Herdecke, Witten
Positions:2003-recent Junior Research Group Leader at the HZI, Braunschweig
Major research interests:Analysis of cell migration in vitro and in vivoT cell activationImmunological defence against pathogens
Selected Publications:Gunzer, M., Kämpgen, E., Bröcker, E.-B., Zänker, K.S., Friedl, P. Adv. Exp. Med. Biol. 1997; 417: 97-103.Gunzer, M., Friedl, P., Niggemann, B., Bröcker, E.-B., Kämpgen, E., Zänker, K.S. J.Leukoc.Biol. 2000; 67: 622-629.Gunzer, M., Schäfer, A., Borgmann, S., Grabbe, S., Zänker, K.S., Bröcker, E.-B., Kämpgen, E., Friedl, P. Immunity 2000; 13: 323-332Gunzer, M., Weishaupt, C., Planelles, L., Grabbe, S. J Immunol Methods 2001; 258: 55-63Gunzer, M., Weishaupt C., Hillmer A., Basoglu Y., Friedl P., Dittmar K.E., KolanusW., Varga G., Grabbe S. Blood 2004; 104:2801-2809.Gunzer M, Riemann H, Basoglu Y, Hillmer A, Weishaupt C, Balkow S, et al. Blood. 2005; 106(7):2424-32.Friedl P, den Boer AT, Gunzer M. Nat Rev Immunol. 2005 Jul;5(7):532-45.Behnsen J, Narang P, Hasenberg M, Gunzer F, Bilitewski U, Klippel N, Rohde M, Brock M, Brakhage AA, Gunzer M. PLoS Pathog. 2007 Feb 2;3(2):e13 [Epub aheadof print]
First name:Matthias
Last name:Gunzer
Acad. Title:Dr.
Address:HZIMascheroder Weg 1D-38124 Braunschweig
Phone and e-mail:++49- 531- 6181 [email protected]
Further information:http://www.helmholtz-hzi.de
Department and function:Head Vaccine Research Group, Microbial Pathogenesis and Vaccine Research, Division of Microbiology, HZI Braunschweig
Education:1976-1981 Medicine, National University Rosario, Argentina1982-1986 Specialisation in Bacteriology, Rosario, Argentina 1988 MD, University of Genoa, Italy1989 Qualifying Medical Graduates Examination, School of
Medicine and Surgery, Genoa, Italy1993 PhD in Microbiology, University of Genoa, Italy2000 Habilitation Medical Microbiology, Hanover Medical
School
Positions:Since 1994 Head Vaccine Research, GBF, Braunschweig, Germany1991 - 1993 Laboratory of Microbial Pathogenesis, Univ. Genoa, Italy1989 - 1991 Division of Microbiology, GBF, Braunschweig, Germany1986 - 1989 Institute of Microbiology, Genoa, Italy1982 - 1986 National University of Rosario, Argentina1982 - 1986 Italian Hospital, Rosario, Argentina1982 - 1986 Children Hospital, Rosario, Argentina
Major research interests:Vaccinology, mucosal immunity, development of antigen delivery systems and adjuvants.
Selected Publications:Schulze K, Goldmann O, Toppel A, Medina E, Guzman CA. Vaccine. 2005; 23(11):1408-13.Rharbaoui F, Bruder D, Vidakovic M, Ebensen T, Buer J, Guzman CA. J Immunol. 2005; 174(3):1317-24Guzman CA, Cebolla A, Beltrametti F, Staender LH, de Lorenzo V. FEBS Lett. 2005; 579(3):813-8.Borsutzky S, Kretschmer K, Becker PD, Muhlradt PF, Kirschning CJ, Weiss S, Guzman CA. J Immunol. 2005; 174(10):6308-13.Schulze K, Medina E, Guzman CA. Vaccine. 2006; 24(9):1446-50.Borsutzky S, Ebensen T, Link C, Becker PD, Fiorelli V, Cafaro A, Ensoli B, Guzman
CA. Vaccine. 2006; 24(12):2049-56.Becker PD, Fiorentini S, Link C, Tosti G, Ebensen T, Caruso A, Guzman CA. Vaccine. 2006;24(25):5269-76.Link C, Ebensen T, Standner L, Dejosez M, Reinhard E, Rharbaoui F, Guzman CA.Microbes Infect. 2006;8(8):2262-9.Schulze K, Olive C, Ebensen T, Guzman CA. Vaccine. 2006;24(35-36):6088-95Ebensen T, Schulze K, Riese P, Link C, Morr M, Guzman CA. Vaccine. 2007; 25(8):1464-1469Olive C, Schulze K, Sun HK, Ebensen T, Horvath A, Toth I, Guzman CA. Vaccine. 2007;25(10):1789-97.
First name:Carlos Alberto
Last name:Guzman
Acad. Title:MD, PhD
Address:HZIMascheroder Weg 138124-Braunschweig
Phone and e-mail:[email protected]
Department and function: Director, Nephrology; Chairman, Department of Internal Medicine
Education:1972-1982 Chemistry, Art History, Medicine in
Tübingen, Berlin and Cardiff
Positions:1992-1996 Assistenzarzt FU Berlin1996-1999 Postdoctoral Fellowship Yale University1992-1997 Professor of Medicine, Franz-Volhard-Klinik
at the Max Delbrück Centre, Berlin1999 Professor of Medicine, MHH
Major research interests:I am interested in acute and chronic changes of the vasculature. I havestarted in analysing signal transduction pathways in vascular smooth muscle cells and gradually moved into endothelial cells. Additionally, I am interested in vascular development, circulating endothelialprogenitor cells and stem cells in the kidney.
Selected PublicationsSchwarz A, Mengel M, Gwinner W, Radermacher J, et al. Kidney Int. 2005; 67(1):341-8Fliser D, Wagner KK, Loos A, Tsikas D, Haller H. J Am Soc Nephrol. 2005; 16(4):1135-40.Schwarz A, Gwinner W, Hiss M, Radermacher J, Mengel M, Haller H. Am J Transplant. 2005; 5(8):1992-6Gwinner W, Menne J, Lonnemann G, Bahlmann F, Koch KM, Haller H. Int J ArtifOrgans. 2005 Dec;28(12):1224-7.Agrawal R, Marx A, Haller H. J Hypertens. 2006; 24(1):185-92Haller H, Viberti GC, Mimran A, Remuzzi G, Rabelink AJ, Ritz E, Rump LC, Ruilope LM, Katayama S, Ito S, Izzo JL Jr, Januszewicz A. J Hypertens. 2006; 24(2):403-8.Menne J, Meier M, Park JK, Boehne M, Kirsch T, Lindschau C, Ociepka R, LeitgesM, Rinta-Valkama J, Holthofer H, Haller H. Kidney Int. 2006 Oct;70(8):1456-62. Schwarz A, Rustien G, Merkel S, Radermacher J, Haller H. Nephrol Dial Transplant. 2007 Feb;22(2):584-91Tossidou I, Kardinal C, Peters I, Kriz W, Shaw A, Dikic I, Tkachuk S, Dumler I, Haller H, Schiffer M. J Biol Chem. 2007 Jan 9; [Epub ahead of print]Meier M, Park JK, Overheu D, Kirsch T, Lindschau C, Gueler F, Leitges M, Menne J, Haller H. Diabetes. 2007 Feb;56(2):346-54.
First name:Hermann
Last name:Haller
Acad. Title:Prof. Dr.
Address:OE 6840Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:[email protected]
Department and function:Head, Gene Regulation and Differentiation And Division of Molecular Biotechnology, HZI Braunschweig
Education:1969-1974 University of Stuttgart-Hohenheim, Food technology1974-1977 PhD thesis at University of Konstanz, Biology
Positions:1978-1980 Post-Doc at MPI f. Molecular Genetics, Berlin and
DKFZ, Heidelberg1981- Research fellow, group leader, head of dept.,
head of division, HZI, Braunschweig
Major research interests:1. Signal transduction in the cytokine system (signalling molecules
and their impact on transcription, cellular and systemic consequences)
2. Biotechnology with mammalian cells (protein production, viral vectors, cellular vaccines)
Selected Publications:Kröger A, Dallügge A, Kirchhoff S., Hauser H. Oncogene 2003, 22:1045-1056Spitzer D, Dittmar KE, Rohde M, Hauser H, Wirth D. J Virol. 2003; 77(10):6070-5Koster M, Lykke-Andersen S, Elnakady YA, Gerth K, et al. Exp Cell Res. 2003;
286(2):321-31Unsinger J, Lindenmaier W, May T, Hauser H, Wirth D. Biochem Biophys Res
Commun. 2004; 319(3):879-87Niedick I, Froese N, Oumard A, Mueller PP, Nourbakhsh M, Hauser H, Koster M. J
Cell Sci. 2004; 117(Pt 16):3447-58Wirth D, Hauser H. Methods Mol Biol. 2004;267:467-76.May T, Hauser H, Wirth D. Nucleic Acids Res. 2004; 32(18):5529-38May T, Wirth D, Hauser H, Mueller PP. Biochem Biophys Res Commun. 2005;
327(3):734-41May T, Mueller PP, Weich H, Froese N, Deutsch U, Wirth D, Kroger A, Hauser H.J Biotechnol. 2005; 120(1):99-110.Froese N, Schwarzer M, Niedick I, Frischmann U, Koster M, Kroger A, Mueller PP,
Nourbakhsh M, Pasche B, Reimann J, Staeheli P, Hauser H. Mol Cell Biol. 2006; 26(1):293-302.
Frahm T, Hauser H, Koster M. J Cell Sci. 2006 Mar 15;119(Pt 6):1092-104.Schucht R, Coroadinha AS, Zanta-Boussif MA, Verhoeyen E, Carrondo MJ, Hauser
H, Wirth D. Mol Ther. 2006 Aug;14(2):285-92.
First name:Hansjörg
Last name:Hauser
Acad. Title:Dr. rer. nat
Address:HZIMascheroder Weg 138124 Braunschweig
Phone and e-mail:++49 [email protected]
Further information:www.helmholtz-hzi.de
Department and function:Clinical ImmunologyResearch Associate
Education:1990 MD, Hannover Medical School
Positions:1990-1992: Internship, Dept. of Immunology and Transfusion
Medicine, Hannover Medical School 1992-1995: Research Fellowship (German Research Council, DFG)
in the Laboratory of Immunobiology, Dana-Farber Cancer Institute/Harvard Medical School, Boston, USA
1995-recent: Resident in Internal Medicine, Clinical Immunology, Hannover Medical School
Major research interests:Analysis of NK cell functions in HIV infectionPrognostic factors in HIV infectionChemokines and chemokine coreceptorsImpact of GBV-C coinfection on HIV progression
Selected Publications:Tillmann HL, Heiken H, Knapik-Botor A, et al. N Engl J Med. 2001; 345(10):715-24.Grosse V, Schulte A, Weber K, Mendila M, Jacobs R, Schmidt RE, Heiken H. AIDS 2002; 16(7):1075-7.Tillmann HL, Stoll M, Manns MP, Schmidt RE, Heiken H. AIDS. 2002; 16(5):808-9.Jacobs R, Weber K, Wendt K, Heiken H, Schmidt RE. J Clin Immunol. 2004; 24(3):281-6. Jacobs R, Heiken H, Schmidt RE. Mol Immunol. 2005; 42(2):239-49.Ansari AW, Bhatnagar N, Dittrich-Breiholz O, Kracht M, Schmidt RE, Heiken H. IntImmunol. 2006;18(10):1443-51
First name:Hans
Last name:Heiken
Acad. Title:Dr. med.
Address:OE 6830Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/immun
Department and function:Group Leader, Molecular Cardiology (Cardiology and Angiology)
Education:1994 PhD in Biology (Genetics and Developmental Biology),
University of ZürichZürich, CH
Positions:1994-1996: Post Doc in the Department of Biology at the EMORY University in Atlanta (Georgia, USA)1997-2001: Post Doc in the Department of Cardiology and
Angiology of Hannover Medical School2001-recent: Group Leader in Molekular Cardiology in the
Department of Cardiology and Angiology
Major research interests:Analysis of mechanisms of stress-dependent signal transductionresponsible for the transition of compenatory hypertrophy to decompensated hypertrophy in the heart. Focus on the gp130-JAK/STAT signaling pathway and AP-1 transcription factors.Regulation and role of pro-angiogenic gene CCN1 in the pathophysiology of the heart.
Selected Publications:Hilfiker-Kleiner D, Hilfiker A, Schieffer B, Engel D, Mann DL, Wollert KC, DrexlerH Cardiovasc Res. 2002; 53(2):460-469.
Hilfiker A., Hilfiker-Kleiner D., Fuchs M., Kaminski K., Lichtenberg, A., RothkötterH., Schieffer B., and Drexler H. Circulation. 2002; 106(2):254-260
Podewski E.K., Hilfiker-Kleiner D., Hilfiker A., Morawitz H., Lichtenberg A., Wollert K.C. and Drexler H. Circulation. 2003Hilfiker-Kleiner D, Kaminski K, Kaminska A., Fuchs M., Klein G., Podewski E., Kiian I., Wollert K.C., Hilfiker A., Drexler H. Circulation 2004; 109(18):2227-33Hilfiker-Kleiner D, Hilfiker A, Fuchs M, et al. Circ Res. 2004; 95(2):187-95.Schieffer B, Selle T, Hilfiker A, Hilfiker-Kleiner D, et al. Circulation. 2004; 110(22): 3493-500.Hilfiker-Kleiner D, Hilfiker A, Kaminski K, Schaefer A, Park JK, Michel K, Quint A, Yaniv M, Weitzman JB, Drexler H. Circulation. 2005; 112(10):1470-7.Hilfiker-Kleiner D, Hilfiker A, Castellazzi M, Wollert KC, Trautwein C, SchunkertH, Drexler H. Cardiovasc Res. 2006;71(1):108-17.Hilfiker-Kleiner D, Landmesser U, Drexler H. J Am Coll Cardiol. 2006;48(9 Suppl):A56-66Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, Forster O, Quint A, Landmesser U, et al. Cell. 2007;128(3):589-600.
First name:Denise
Last name:Hilfiker-Kleiner
Acad. Title:PhD
Address:OE 6887Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/cardiology
Department and function:Professor, Biochemistry (Physiological Chemistry)
Education:1980 Diploma in Biology, University of Hannover1985 Ph. D., Ludwig-Maximilians-University Munich1993 Habilitation in Immunology, Medical School Hannover
Positions:1985-1987: Postdoctoral fellow at the Weizmann Institute of
Science, Rehovot, Israel1987-2001: Group leader, Institute of Pharmacology, Medical
School Hannover2001-2003: GBF-BraunschweigSince 2003: Professor for Biochemistry of Cellular Signal
Transduction, Institute of Biochemistry/Physiological Chemistry, Medical School Hannover
Major research interests:Post-transcriptional control of gene expression in inflammation
- cis-acting RNA elements- regulatory RNA-binding proteins- signalling pathways affecting post-transcriptional mechanisms
Selected Publications:Winzen R., Kracht M., Ritter B., Wilhelm A., Chen C.-Y.A., Shyu A.-B., Müller M., Gaestel M., Resch K., Holtmann. H. EMBO J. 1999; 18:4969-4980.Holtmann H., Winzen R., Holland P., Eickemeier S., Hoffmann E., Wallach D., Malinin N., Cooper J.A., Resch K., Kracht M. Mol. Cell. Biol. 1999; 19:6742-6753.Bollig F., Winzen R., Kracht M., Ghebremedhin B., Ritter B., Wilhelm A., Resch K., Holtmann H. Eur. J. Biochem. 2002; 269:5830-5839.Bollig F, Winzen R, Gaestel M, Kostka S, Resch K, Holtmann H. Biochem BiophysRes Commun. 2003;301(3):665-7Winzen R, Gowrishankar G, Bollig F, Redich N, Resch K, Holtmann H .Mol Cell Biol. 2004; 24(11):4835-47Gowrishankar G, Winzen R, Bollig F, Ghebremedhin B, Redich N, Ritter B, Resch K, Kracht M, Holtmann H. Biol Chem. 2005; 386(12):1287-93. Gowrishankar G, Winzen R, Dittrich-Breiholz O, Redich N, Kracht M, Holtmann H.Biol Chem. 2006;387(3):323-7.
First name:Helmut
Last name:Holtmann
Acad. Title:Prof. Dr.
Address:OE 4310Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/biochemie
Department and function:Institute for Transfusion Medicine, Group Leader Cell Therapy
Education:1990-97 Graduated in Medicine, University of Bochum1999 M.D., University of Bochum1998-99 Postgraduate training in Hematology and Oncology,
University of Cologne2002-05 Postgraduate training in Transfusion Medicine,
University of Düsseldorf and Hannover Medical School
Positions:1998-99 Resident, Internal Medicine, University of Cologne2000-02 Research Fellow, FHCRC, Seattle, USA2002-04 Physician, Cord Blood Bank, Institute for Transplantation
Diagnostics & Cell Therapies, University of Düsseldorf2004-recent Group leader, Institute for Transfusion Medicine,
Hannover Medical School, Hannover
Major research interests:Cell and Gene Therapy, Immunogenetics, Stem Cell Biology, Large Animal Studies, Stem Cell Transplantation
Selected Publications:Horn, P.A., J. Morris, A. Bukovsky, et al. Gene Therapy 2002. 9: 1464-1471Neff, T., P.A. Horn, V.E. Valli, A.M. Gown, et al. Blood 2002. 100: 2026-2031Horn, P.A.*, M.S. Topp*, J.C. Morris, R.S. Riddell, et al. Blood 2002. 100: 3960-7Neff, T.*, P.A. Horn*, et al. Journal of Clinical Investigation 2003. 112: 1581-1588Horn, P.A., B.M. Thomasson, B.L. Wood, et al. Blood 2003. 102: 4329-4335Storek, J., T. Gillespy III, H. Lu, A. Joseph, et al. Blood 2003. 101: 4209-4218Kiem, H.P., et al. Molecular Therapy 2004 9, 389-395Horn, P.A., K.A. Keyser, L.J. Peterson, T. Neff, et al. Blood 2004. 103: 3710-3716Horn, P.A., Morris, J.C., Neff, T., Kiem, H.P. Molecular Therapy 2004. 10, 417-431Horn, P.A., Blasczyk, R. Tissue Antigens 2005. 66, 56-57Horn, P.A., Mansmann V., Blasczyk, R. Tissue Antigens 2005. 66, 335-337Horn, P.A., DeLuca, D., Jindra, P., Blasczyk, R. 2006. Human Immunology 2005; 66(12):1254-7.Eiz-Vesper, B., Horn, P. A., et al. Transfusion 2006;46(7):1210-20.Horn PA, Elsner HA, Blasczyk R. Pediatr Transplant. 2006 Sep;10(6):753-4.Horn PA, Tani K, Martin U, Niemann H. Cloning Stem Cells. 2006 Fall;8(3):124-9.
First name:Peter A.
Last name:Horn
Acad. Title:Dr. med.
Address:OE 8350Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/transfusion/transfusionsmedizin/
Department and function: Group Leader, Clinical Immunology
Education:1981-1986 Biology in Hannover
Positions:1987-recent Scientist in the Division of Clinical Immunology, MHH1992 PhD in Biology, MHH2003 Habilitation in Immunology, MHH
Major research interests:Analysis of Natural Killer (NK) cell subpopulations. Our particularinterest is focused on NK cells with weak cytoxic capacity that aresupposed to play an important role in immune regulation.
Selected PublicationsJacobs R, Hintzen G., Kemper A., Beul K., et al. Eur J Immunol 2001; 31: 3121-3126.Jacobs R., Pawlak C. R., Mikeska E., Meyer-Olson D., et al.. Rheumatol 2001; 40: 868-875.Kittner J. M., Jacobs R., Pawlak C. R., Heijnen C. J., Schedlowski M., Schmidt R. E.. Rheumatol 2002; 41: 1031-1039.Straub R. H., Kittner J. M., Heijnen C. J., Schedlowski M., Schmidt R. E., Jacobs R. J Rheumatol 2002; 29: 1659-1664.Jacobs R, Weber K, Wendt K, Heiken H, Schmidt RE J Clin Immunol. 2004; 24(3):281-6Jacobs R, Heiken H, Schmidt RE Mol Immunol. 2005; 42(2):239-49Wendt K, Wilk E, Buyny S, Buer J, Schmidt RE, Jacobs R. J Leukoc Biol. 2006; 80(6):1529-41.
First name:Roland
Last name:Jacobs
Acad. Title:PD Dr.
Address:OE 6830Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/kliniken/immun
Department and function:Assistant and research group leader department gastroenterology, hepatology, endocrinology
Education:1996 Master in medicine, University of Hamburg1997 MD, Dept. Pharmacology, Friedrich-Alexander
University, Erlangen
Positions:1996-1999: Research fellow and assistant Dept. Gastroenterology,
MHH, Hannover1998: Research Fellow, German Primate Center Goettingen1999-2003: Postdoctoral fellowship dept. cancer immunology and
AIDS, Dana Farber Cancer Institue, Harvard MedicalSchool, Boston
2003-recent: Assistant and research group leader departmentGastroenterology, Hepatology, Endocrinology
Major research interests:Mechanisms and regulation of immune tolerance in autoimmunity, alloimmunity and chronic infection
Selected Publications:Jaeckel E, Heringlake S, Berger D, Brabant G, Hunsmann G, Manns MP. Diabetes 1999; 48(1):209-14. Jaeckel E, Cornberg M, Santantonio T, Mayer J, et al. New England Journal of Medicine 2001; 345:1452-1457.Jaeckel E, Klein L, Martin-Orozco N, von Boehmer H. J Exp Med 2003; 197: 1635-1644.Wiegand J, Jackel E, Cornberg M, Hinrichsen H, et al. Hepatology 2004; 40:98-107.Jaeckel E, El-Armouche A, Boheler KR, Boknik P, et al. Biochem Biophys Res Comm 2004; 318: 219-226.Jaeckel E, Lipes MA, von Boehmer H. Nat Immunol 2004; 5: 1038-1035.Jaeckel E, von Boehmer H, Manns MP Diabetes 2005; 54: 306-310.Jaeckel E, Kretschmer K, Apostolou I, von Boehmer H. Semin Immunol. 2006; 18(2):89-92
First name:Elmar
Last name:Jaeckel
Acad. Title:MD
Address:OE6819TPFZ, K11/01-1450
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/gastro/gastro.htm
Department and function:Group leader (Institute of Medical Microbiology and Hospital Epidem.)
Education:1996 PhD in Biology (Microbiology/Biochemistry/Cell
Biology), Ruhr-University Bochum, Germany
2003 Habilitation in Medical Microbiology, University of Würzburg, Germany
Positions:1998-1999: Junior Research Group Leader, Dept. Medical
Microbiology, Ruhr-University Bochum, Germany
1999-2000: Post-Doctoral Research, Institute for Cellular Pathology, Université Catholique de Louvain, Bruxelles/Brussel, Belgium
2000-2004: Junior Research Group Leader, Institute for Hygiene and Microbiology, University of Würzburg, Germany
from 2004: Research Group Leader “Cellular Microbiology”Institute for Medical Microbiology and Hospital Epidem. at Hannover Medical School
Major research interests:Characterization of virulence mechanisms of pathogenic bacteriaBacterial sensing, signal transduction and gene regulationBacterial motility and secretion processesInfluence of bacteria on cellular signaling and immune responses in health (commensals) and disease (pathogens) in the gastrointestinal tract
Selected Publications:Schreiber S., Stüben M., Groll C., Scheid P., et al. Natl. Acad. Sci. 2004; 101: 5024-5029.Niehus E., Gressmann H., Ye F., Schlapbach R., et al. Mol. Microbiol. 2004; 52: 947-961. Schmausser B., Josenhans C., Endrich S., Suerbaum S., et al. Infect. Immun. 2004; 72: 6773-6779.Schreiber S, Bucker R, Groll C, Azevedo-Vethacke M, Garten D, Scheid P, et al. Infect Immun. 2005; 73(3):1584-9Schreiber S, Bucker R, Groll C, Azevedo-Vethacke M, Scheid P, Gatermann S, Josenhans C, Suerbaum S. Arch Microbiol. 2006;184(5):335-40.Andrzejewska J, Lee SK, Olbermann P, Lotzing N, Katzowitsch E, Linz B, Achtman M, Kado CI, Suerbaum S, Josenhans C. J Bacteriol. 2006;188(16):5865-77.Ye F, Niehus E, Drlica K, Josenhans C, Suerbaum S. Int J Med Microbiol. 2007 Jan 31; [Epub ahead of print]
First name:Christine
Last name:Josenhans
Acad. Title:P.D. Dr. rer. nat. (Ph.D.)
Address:OE 5210Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/mikrobiologie/
Department and function: Head of Department of Toxicology
Education:1976-1980 Pharmacy, Universität Münster1981-1987 Medicine, Freie Universität Berlin
Positions:1989-1995 Postdoc positions in Pharmacology at the Universities
of Giessen, Essen, Homburg/Saar1997 Post Orange Fellowship of INSERM in Nice, France1995-2000 Assistant Professor at the University of Freiburg2000 Professor of Toxicology, MHH
Major research interests:The molecular and cellular mode of action of bacterial proteintoxins and the functional consequences on the signal transductionof the target cells.
Selected Publications
Vetter, IR, Hofmann, F, Wohlgemut, S, Herrmann, C, and Just, I (2000) J. Mol. Biol. 301:1091-1095 Wilde, C, Chhatwal, GS, Schmalzing, G, Aktories, K, and Just, I (2001) J. Biol. Chem., 276:9536-9542Wilde, C, Barth, H, Sehr, P, Han, L, Schmidt, M, Just, I, Aktories, K (2002) J. Biol. Chem. 277:14771-14776 Gerhard, R, John, H, Aktories, K, and Just, I (2003) Mol. Pharmacol. 63:1349-1355Genth H, Gerhard R, Maeda A, Amano M, Kaibuchi K, Aktories K, Just, I. (2003) J. Biol. Chem. 278: 28523-28527Ahnert-Hilger G, Höltje M, Große G, Pickert G, Mucke C, Nixdorf-Bergweiler B, Boquet P, Hofmann F, and Just I. (2004) J. Neurochem. 90:9-18Gerhard, R, Tatge, H., Genth, H., Thum, T., Borlak, J., Fritz, G., and Just, I. (2005)J. Biol. Chem. 280:1499-1505Theodoresu, D, Wittke, S, Ross, MM, Walden, M, Conaway, M, Just, I, Mischak, H, Frierson, H (2006) Lancet Oncology 7:230-240.
First name:Ingo
Last name:Just
Acad. title:Prof. Dr.
Address:OE 5340Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/institute/212.html?&no_cache=1/
Department and function:Professor, Molecular Biology of Vertebrates
Education:1983-1989 University of Tübingen, Biochemistry1987-1988 Queen Mary College, London, Biochemistry1989-1990 Diploma thesis, MPI Tübingen1990-1993 PhD thesis, MPI Tübingen
Positions:1993-1994 Postdoc, MPI Tübingen1994-1996 Postdoc, Harvard University1997-2001 Group leader, MPI FreiburgSince 2001 C3 Professor, MHH
Major research interests:Genetic control of vertebrate (mouse) development:- Organogenesis (organs of mesodermal origin like kidneys, skeleton,
muscles, heart)- Function of Wnt and Tbx genes in development
Selected Publications:Kispert A, Vainio S, McMahon AP. Development 1998; 125: 4225-4234Herrmann BG, Koschorz B, Wertz K, McLoughlin KJ, Kispert A. Nature 1999; 402: 141-146Leitges M, Neidhardt L, Haenig B, Herrmann BG, Kispert A. Development 2000; 127: 2259-2267Kohlhase J, Heinrich M, Liebers M, Frohlich Archangelo L, Reardon W, Kispert A. Cytogenet Genome Res. 2002; 98(4):274-7Moeller C, Swindell EC, Kispert A, Eichele G. Development. 2003; 130(21):5103-11. Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, Kispert A. Genes Dev. 2004; 18(10):1209-21Haenig B, Kispert A . Dev Genes Evol. 2004; 214(8):407-11.Singh MK, Petry M, Haenig B, Lescher B, Leitges M, Kispert A. Mech Dev. 2005; 122(2):131-44Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Burger A, Ericson J, Kispert A. Development. 2005 Jun;132(12):2697-707.Airik R, Bussen M, Singh MK, Petry M, Kispert A. J Clin Invest. 2006;116(3):663-74.Barrionuevo F, Taketo MM, Scherer G, Kispert A. Dev Biol. 2006;295(1):128-40.Christoffels VM, Mommersteeg MT, Trowe MO, Prall OW, de Gier-de Vries C, Soufan AT, Bussen M, Schuster-Gossler K, Harvey RP, Moorman AF, Kispert A. Circ Res. 2006 Jun 23;98(12):1555-63
First name:Andreas
Last name:Kispert
Acad. Title:Prof. Dr.
Address:OE 5250Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:http://www.ifm-mhh.de.vu/
Department and function:Professor; Pediatric Hematology/Oncology
Education:1983-1990 Medical School (University Ulm, Munich)1992 Magister Artium, Philosophy2000 Doctorat Immunology (Institut Pasteur, Paris)
Positions:1990 Residency in Pediatrics, University Munich1991-1994 Residency and Research Associate Hôpital Necker
Enfants Malades, Paris1994-1995 Residency in Pediatrics, University Freiburg1995-1998 Clinical and Research Fellow
Children‘s Hospital, Harvard Medical School Boston1998-2000 Instructor in Pediatrics and Research Associate, Howard
Hughes Medical Instit., Harvard Medical School, Boston2000- Hannover Medical School
Major research interests:Gene Therapy, Tumor Immunology, Stem Cell Biology
Selected Publications:Snapper SB, Takeshima F, Rosen FS, Antón I, Thomas S, et al. Nat Cell Biol 2001;3:897-904Robert C, Klein C, Cheng G, Kogan A, Mulligan RC, et al. Gene Therapy 2003; 10(17):1479-86Klein C, Nguyen D, Liu CH, Mizoguchi E, Bhan AK, Rosen FS, et al. Blood 2003; 101(6):2159-66Klein C, Baum C Hematol J. 2004;5(2):103-11Cloppenborg T, Stanulla M, Zimmermann M, Schrappe M, Welte K, Klein C.Leukemia. 2005; 19(1):44-8.Rathinam C, Geffers R, Yucel R, Buer J, Welte K, Moroy T, Klein C. Immunity. 2005; 22(6):717-28.Maecker B, Mougiakakos D, Zimmermann M, Behrens M, Hollander S, Schrauder A, Schrappe M, Welte K, Klein C. Leukemia. 2006;20(4):645-9.Rathinam C, Sauer M, Ghosh A, Rudolph C, Hegazy A, Schlegelberger B, Welte K, Klein C. Leukemia. 2006;20(5):870-6.Dewey RA, Avedillo Diez I, Ballmaier M, Filipovich A, Greil J, Gungor T, Happel C, Maschan A, et al. Exp Hematol. 2006;34(9):1161-9.Klein C, Grudzien M, Appaswamy G, Germeshausen M, Sandrock I, Schaffer AA, Rathinam C, Boztug K, et al. Nat Genet. 2007 Jan;39(1):86-92.Bohn G, Allroth A, Brandes G, Thiel J, Glocker E, Schaffer AA, Rathinam C, Taub N, et al. Nat Med. 2007;13(1):38-45.
First name:Christoph
Last name:Klein
Acad. Title:Prof. Dr., PhD
Address:OE 6780Hannover Medical School
Phone and e-mail:+49-511-532 [email protected]
Further information:www.mh-hannover.de/Kliniken/paed_haemonko/Klinik.htm
Department and function:Assistant Medical Director, Medical Microbiology
Education:1980 - 86 Study of Medicine at the Johannes-Gutenberg University
Mainz1988 - 91 Experimental training in Molecular Biology and Cell
Biology at the Baylor College of Medicine, Department ofCell Biology, Houston, Texas, Medical Center
2000 Consultant with board certification in Med. Microbiol.
Positions:1987 - 88 Research Assistent in the Department of Medical
Microbiology, Johannes-Gutenberg University, Mainz1991 -2000 Research Assistant and, from 2001 on, Assistant Medical
Director at the Department of Medical Microbiology, MHH
Major research interests:Basic research on …1. Chlamydia: Bacteria–host-cell interaction, regulated host-cell genes, mechanisms and signalling pathways2. Complement: Anaphylatoxic peptides C3a, C5a and their G-proteincoupled receptors as part of the innate immunity, receptor regulation on various levels including gene-regulation and interaction with cytokines
Selected Publications:Settmacher B, Rheinheimer C, Hamacher H, Ames RS, et al. Eur J Immunol. 2003; 33(4):920-7Hess S, Peters J, Bartling G, Rheinheimer C, et al. Cell Microbiol. 2003; 5(11):785-95Otto M, Hawlisch H, Monk PN, Muller M, et al. J Biol Chem. 2004; 279(1):142-51Godau J, Heller T, Hawlisch H, Trappe M, et al. J Immunol. 2004; 173(5):3437-45.Fischer SF, Vier J, Kirschnek S, Klos A, et al. J Exp Med. 2004; 200(7):905-16.Peters J, Hess S, Endlich K, Thalmann J, Holzberg D, Kracht M, Schaefer M, Bartling G, Klos A. Cell Microbiol. 2005; 7(8):1099-108Schaefer M, Konrad S, Thalmann J, Rheinheimer C, Johswich K, Sohns B, Klos A. J Biol Chem. 2005; 280(51):42113-23Johswich K, Martin M, Thalmann J, Rheinheimer C, Monk PN, Klos A. J Biol Chem. 2006;281(51):39088-95.
First name:Andreas
Last name:Klos
Acad. Title:Prof. Dr.
Address:OE 5210Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/institute/mikrobiologie/
Department and function:Dept. of Experimental Hematology (head: Prof.Dr.C.Baum),Project Leader
Education:1997 PhD in Biology (Molecular Genetics),
University of Vienna1993 Diploma (Mag.rer.nat.) in Molecular Genetics
University of Vienna
Positions:2003-present: Resarch Associate at the
Institute of Experimental Hematology(head Prof.Dr.C.Baum), Hannover Medical School
1998-2003: Research Associate at the Heinrich-Pette-Institute for Experimental Viroloy and Immunology (HPI), Hamburg
1995-1998: Assistant Professor (“Vertragsassistent”) at the University of Vienna,Institute of Medical Biochemistry.
Major research interests:- In vitro generation of Hematopoietic Stem Cells (HSCs) from
Embryonic Stem (ES-) Cells suitable for transplantation- Manipulation of stem cell self-renewal and differentiation by the
homeodomain transcription factor HOXB.
Selected Publications:Pilat, S., Carotta, S., Schiedlmeier, B., et al. (2005) PNAS, 102: 12101-12106.Will, E., Speidel, D., Wang, Z. et al. (2006) Cell Cycle, 5, 14-22.Schiedlmeier, B., Klump, H., Will, E., et al. (2003) Blood, 101: 1759-1768.Will, E., Klump, H., Heffner, N., et al. (2002) Nucl Acids Res, 30: e59.Klump,H., Schiedlmeier,B., Vogt, B., et al. (2001) Gene Ther, 8, 811-817.
First name:Hannes
Last name:Klump
Acad. Title:Dr.rer.nat.
Address:OE 6960Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/zellth/
Department and function:Group Leader, Biochemistry (Physiological Chemistry)
Education: 1978-1985 Medical School, Charkov, Ukraine1987-1991 PhD thesis
Positions:Research Assistent
Major research interests:MAPK cascades activated by stress or cytokinesSignalling events that are triggered by p38 activity,and analyse how these events contribute to specific gene expression and cellular responses.
Selected Publications:Kotlyarov A., Neininger C., Schubert R., Eckert C., Birchmeier H-D, et al. Nature Cell Biol. 1999; 1: 94-97.Kotlyarov A, Gaestel M. Biochem. Soc. Trans. 2002; 30: 959-963.Kotlyarov A, Yannoni Y, Fritz S, Laaß K, Telliez J-B, et al. Mol. Cell. Biol. 2002; 22: 4827–4835.Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, et al. Mol Cell Biol. 2003; 23(21):7732-41.Wu Y, Hannigan MO, Kotlyarov A, Gaestel M, Wu D, Huang CK. Biochem BiophysRes Commun. 2004; 316(3):666-7Schumacher S, Laass K, Kant S, Shi Y, et al. EMBO J. 2004; 23(24):4770-9.Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Mol Cell Biol. 2006;26(6):2399-407Vertii A, Hakim C, Kotlyarov A, Gaestel M. J Biol Chem. 2006;281(37):26966-75.Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M. J Biol Chem. 2006;281(46):35511-9.Ronkina N, Kotlyarov A, Dittrich-Breiholz O, Kracht M, Hitti E, Milarski K, Askew R, Marusic S, Lin LL, Gaestel M, Telliez JB. Mol Cell Biol. 2007;27(1):170-81.
First name:Alexey
Last name:Kotlyarov
Acad. Title:MD
Address:OE4310Hannover Medical School
Phone and e-mail:[email protected]
Further information:www.mh-hannover.de/ institute/biochemie/
Department and function:Director, Institute of Pathology
Education:1976-1982 Study of Medicine, University of Kiel1985 Doctoral thesis, University of Kiel1991 Habilitation , University of Kiel
Positions:1984 - 1993: Institute of Pathology, University of Kiel; senior
registrar since 19911993 - 1998: Professor and Deputy Director Institute of Pathology
University of Würzburgsince 1998: Professor and Head of the Department of Pathology,
Medizinische Hochschule Hannover
Major research interests:Molecular pathology of breast cancer and leukemiasDifferentiation and regeneration of normal tissues
Selected Publications:Serinsoz E, Neusch M, Busche G, Wasielewski R, Kreipe H, Bock O. Br J Haematol. 2004; 126(3):313-9.Mengel M, Jonigk D, Wilkens L, Radermacher J, von Wasielewski R, Lehmann U, Haller H, Mihatsch M, Kreipe H. Am J Pathol. 2004;165(6):2079-85.Bock O, Loch G, Schade U, Büsche G, von Wasielewski R, Wiese B, Kreipe H. Br J Haematol. 2005; 130:76-82Brakensiek K, Langer F, Schlegelberger B, Kreipe H, Lehmann U. Br J Haematol. 2005l;130(2):209-17.Lehmann U, Kreipe H. Methods Mol Med. 2006;120:65-75.Brocker V, Langer F, Fellous TG, Mengel M, Brittan M, Bredt M, Milde S, Welte T, Eder M, Haverich A, Alison MR, Kreipe H, Lehmann U. Am J Respir Crit Care Med. 2006;173(11):1276-82.Bock O, Neuse J, Hussein K, Brakensiek K, Buesche G, Buhr T, Wiese B, Kreipe H. Am J Pathol. 2006;169(2):471-81.Bock O, Hussein K, Neusch M, Schlue J, Wiese B, Kreipe H. Eur J Haematol. 2006; 77(6):463-70.Schade U, Bock O, Vornhusen S, Jager A, Busche G, Lehmann U, Kreipe H. HumPathol. 2006;37(9):1153-61Bock O, Hussein K, Brakensiek K, Buhr T, Schlue J, Wiese B, Kreipe H.Leuk Res. 2006 Oct 6; [Epub ahead of print]Mengel M, Gwinner W, Schwarz A, Bajeski R, Franz I, Brocker V, Becker T, NeippM, Klempnauer J, Haller H, Kreipe H.Am J Transplant. 2007;7(2):356-65
First name:Hans H.
Last name:Kreipe
Acad. Title:Prof. Dr.
Address:OE 5110Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/pathologie
Department and function:Head of Immunology, Allergology and Clinical Inhalation Research, ITEM
Education:1981-89 Medicine in Hannover, Göttingen and Hartford (USA)1998-2000 Degree in Internal Medicine, Respiratory Medicine,
Allergology and Intensive Care Medicine, Hannover Medical School (MHH)
1999 Habilitation in Internal Medicine (MHH)
Positions:1989-93 and1995-2000: Assistenzarzt Medical School Hannover (MHH)1993-95: Postdoctoral Fellowship University Bochum and
University Southampton (German Research CouncilScholarship)
since 2000: Professor of Immunology, Allergology and Clinical Inhalation Research, MHHand Head of Department Immunology, Allergology and Clinical Inhalation Research, Fraunhofer ITEM
Major research interests:Pathophysiology and therapeutic interventions of airway diseases, in particular asthma. Preclinical and clinical research.
Selected Publications:Erpenbeck VJ, Hagenberg A, Dulkys J, Elsner J, Krentel H, et al. Am J Respir CritCare Med 2004; 169; 578-586.Hohlfeld JM, Schmiedl A, VJ Erpenbeck, Venge P, Krug N. J Allergy Clin Immunol2004; 113: 496-502.Weigt H, Muhlradt PF, Larbig M, Krug N, Braun A. J Immunol. 2004; 172:6080-6.Schaumann F, Borm PJ, Herbrich A, Knoch J, et al. Am J Respir Crit Care Med. 2004; 170(8):898-903.Baelder R, Fuchs B, Bautsch W, Zwirner J, et al. J Immunol. 2005; 174(2):783-9.Krug N, Hohlfeld JM, Geldmacher H, Larbig M, Heermann R, Lavallee N, Nguyen DT, Petzold U, Hermann R. Allergy. 2005;60(3):354-9.Erpenbeck VJ, Hagenberg A, Krentel H, Discher M, Braun A, Hohlfeld JM, Krug N. Int Arch Allergy Immunol. 2006;139(4):306-316Erpenbeck VJ, Ziegert M, Cavalet-Blanco D, Martin C, Baelder R, Glaab T, Braun A, Steinhilber W, et al. Clin Exp Allergy. 2006;36(7):930-40.Larbig M, Burtin B, Martin L, Stamm H, Luettig B, Hohlfeld JM, Krug N. Br J ClinPharmacol. 2006;62(2):158-64.
First name:Norbert
Last name:Krug
Acad. Title:Prof. Dr.
Address:Fraunhofer Institute forToxicology and Experimental MedicineNikolai-Fuchs-Str. 130625 Hannover
Phone and e-mail:++49- 511- 5350 [email protected]
Further information:www.item.fraunhofer.de
Department and f unction:Group Leader and Head of the Laboratory of Molecular Diagnostics; Pathology
Education:1986-1992 University of Hannover, Biochemistry1992-1996 PhD, Molecular Biology
Positions:1996-1998 Head Laboratory of Molecular Diagnostics
Institute of Pathology, Bielefeldsince 1999 Research Group Leader and Head of the
Laboratory of Molecular Diagnostics,Institute of Pathology, Hannover Medical School
Major research interests:Epigenetics of malignant neoplasiaTumor evolutionMolecular diagnosis of neoplasiaMain focus on breast cancer and hematological neoplasia in humans
Selected Publications:Kleeberger W, Versmold A, Rothamel T, Glockner S, Bredt M, et al. Am J Pathol. 2003; 162(5):1487-94Tessema M, Langer F, Dingemann J, Ganser A, Kreipe H, Lehmann U.Leukemia. 2003; 17(5):910-8. Lehmann U, Brakensiek K, Kreipe H. Ann Hematol. 2004; 83(3):137-52Lehmann U, Kreipe H. Methods Mol Biol. 2004; 287:207-18.Langer F, Stickel J, Tessema M, Kreipe H, Lehmann U. Leuk Res. 2004; 28(10):1081-3.Brakensiek K, Langer F, Kreipe H, Lehmann U. Blood. 2004; 104(5):1586-7Tessema M, Langer F, Bock O, Seltsam A, Metzig K, Hasemeier B, Kreipe H, Lehmann U. Int J Oncol. 2005; 26(2):499-507.Langer F, Dingemann J, Kreipe H, Lehmann U. Leuk Res. 2005; 29(3):325-9.Lehmann U, Berg-Ribbe I, Wingen LU, Brakensiek K, Becker T, KlempnauerJ, et al. Clin Cancer Res. 2005; 11(10):3654-60.Brakensiek K, Langer F, Kreipe H, Lehmann U. Leuk Res. 2005; 29:1357-60.Brakensiek K, Langer F, Schlegelberger B, Kreipe H, Lehmann U. Br J Haematol. 2005; 130(2):209-17.Lehmann U, Kreipe H. Methods Mol Med. 2006;120:65-75.Brocker V, Langer F, Fellous TG, Mengel M, Brittan M, Bredt M, Milde S, Welte T, Eder M, Haverich A, Alison MR, Kreipe H, Lehmann U. Am J RespirCrit Care Med. 2006;173(11):1276-82.Brakensiek K, Wingen LU, Langer F, Kreipe H, Lehmann U. Clin Chem. 2007; 53(1):17-23.
First name:Ulrich
Last name:Lehmann
Acad. Title:PD Dr. rer. nat.
Address:OE 5102Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/ institute/pathologie/
Department and function:Division of Microbiology, Head of the Junior Research Group Infection Genetics, HZI – Helmholtz Center for Infection Research
Education:1997 PhD in Biology (Genetics), University of Bielefeld
Positions:1997-2000: Postdoctoral Research Fellow at the University of
Pennsylvania, Medical School, Philadelphia, USA2000-2001: Senior Research Scientist at the Institute of Mammalian
Genetics, National Research Centre for Health and Environment (GSF), in Munich
2001-recent: Junior Research Group Leader at the HZI.
Major research interests:Host-pathogen interactions, Mouse infection models, Macrophage functions during infections, Clearance of apoptotic cells, Infection Genetics.
Selected Publications:Hough, R.B., Lengeling, A., Bedian, V., Bucan, M. PNAS 1998; 95: 13800-13805.Lengeling, A., Wiltshire, T., Otmani, C., Bucan, M. Genome Res.1999; 9: 732-738.Lengeling, A., Pfeffer, K. and Balling, R. Mamm. Genome 2001; 12: 261-271.Schneider, J.E., Böse, J., Bamforth, S.D., Gruber, A.D., Broadbent, C., Clarke, K., Neubauer, S., Lengeling, Bhattacharya, S. BMC Dev. Biol. 2004; 4: 16.Böse, J., Gruber, A.D., Helming, L., Schiebe, S., Wegener, I., Hafner, M., Beales, M., Köntgen, F., Lengeling, A. Journal of Biology 2004; 3, 15.Helming L, Bose J, Ehrchen J, Schiebe S, Frahm T, Geffers R, Probst-Kepper M, Balling R, Lengeling A. Blood. 2005; 106(13):4351-8Medina E, Lengeling A. Brief Funct Genomic Proteomic. 2005; 4(3):248-57.
First name:Andreas
Last name:Lengeling
Acad. Title:Dr. rer. nat.
Address:Mascheroder Weg 138124 Braunschweig
Phone and e-mail:[email protected]
Further information:www.helmholtz-hzi.de
Department and function:Project leaderDept. Experimental Hematology
Education:1993 Master of Medicine (equivalent to MD)
Tongji Medical School, Wuhan, PR. China1998 MD, University of Hamburg, Hamburg2006 Habilitation and venia legendi in
Experimental Hematology, Hannover Medical School
Positions:1993-1995 Clinical and Research fellow, Tongji Medical School1995-1996 Clinical fellow, Clinic of Dr. Kleeberg (HOPA,
Hamburg)1996-1998 Research fellow, Center for Bone Marrow
Transplantation, University Hospital Eppendorf,Hamburg
1999-2002 Faculty member and Deputy Director Department of HematologySun Yat-Sen Memorial HospitalSun Yat-Sen University, Guangzhou, PR. China
2000-2002 Postdoctoral fellowDepartment of Cell & Virus GeneticsHeinrich-Pette-Institute, University of Hamburg
2001-04.2006 Staff scientist, project leaderDept. Hematology, Hemostaseology and Oncology Hannover Medical School
04.2006- Project leader, Dept. Experimental Hematology
Major research interests:1) Leukemogenesis of receptor tyrosine kinases;2) Stem cell biology; 3) Gene therapy
Selected Publications:Li Z et al., Science 2002;296:497Li Z et al., Leukemia 2002;16:1655-63Li Z et al., Experimental Hematology 2003; 31:1206-1214Baum C et al., Blood 2003;101:2099-2113Baum C et al., Molecular Therapy 2004;9:5-13Kustikova OS et al., Science 2005;308:1171-1174Schambach A et al., Gene Therapy 2006;13:1037-1047Kustikova OS et al., Blood 2007 in press
First name:Zhixiong
Last name:Li
Acad. Title:PD Dr.med.
Address:OE 6862Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Department and functionGroup Leader, Cell Biology
Education:1982-1987 Biology, Technical University of Munich1988-1992 PhD Thesis, MPI for Biochemistry, Martinsried
Positions:1992-1997 Postdoc at Washington University, St. Louis, MO, USA1997-2000 Assistant in the Department of Immunobiology,
University of Bonnsince 2000 Assistant in the Department of Cell Biology
Major research interests:Antigen processing and presentation; intracellular sorting of MHC II molecules, antigens and cofactors for antigen processing; lipid rafts and their function in MHC II biology; roles of intestinal epithelial cells in mucosal immunity
Selected Publications:Lindner R., Unanue E. EMBO J. 1996; 15: 6910-6920.Lindner R. Electrophoresis 2001; 22: 386-393.Lindner R. Traffic 2002; 3: 133-146.Karacsonyi C, Knorr R, Fulbier A, Lindner R J Biol Chem. 2004; 279(33):34818-2Karacsonyi C, Bedke T, Hinrichsen N, Schwinzer R, Lindner R. J Leukoc Biol. 2005; 78(5):1097-105.
First name:
Robert
Last name:Lindner
Acad. Title:Dr. rer. nat.
Address:OE 4130Hannover Medical School
Phone and e-mail:++49- 511- 532-2918
Further information:www.mh-hannover.de/Institute/Zellbiologie/
Department and function:Group Leader, Gastroenterology, Hepatology and Endocrinologyand Molecular Biology
Education:6/96 MD1/98-12/00 Post Doc Fred Hutchinson Cancer Center, Seattle WA;
USA
Positions:since 1/96 Dept. of Gastroenterology, MHHsince 2/01 Dept.of Gastroenterology and Institute for Molecular
Biology
Major research interests:My scientific interest concentrates on the understanding of themammalian cell cycle, specifically on the control of cyclin dependentkinases. Our research tries to elucidate the molecular regulation of cyclin kinase inhibitors by proteolytic mechanisnms. We are usingbiochemistry and mouse models as our main tools.
Selected Publication:Malek NP, Sundberg H, McGrew S, Nakayama K, Kyriakides TR, Roberts J. Nature2001; 413: 323-27.Zender L, Hutker S, Liedtke C, Tillmann HL, Zender S, et al. Proc Natl Acad SciUSA 2003; 100(13):7797-802.Kossatz U, Dietrich N, Zender L, Buer J, Manns MP, Malek NP. Genes Dev. 2004; 18(21):2602-7Timmerbeul I, Garrett-Engele CM, Kossatz U, Chen X, Firpo E, Grunwald V, Kamino K, Wilkens L, Lehmann U, Buer J, Geffers R, Kubicka S, Manns MP, Porter PL, Roberts JM, Malek NP. Proc Natl Acad Sci U S A. 2006;103(38):14009-14.Kossatz U, Vervoorts J, Nickeleit I, Sundberg HA, Arthur JS, Manns MP, Malek NP.EMBO J. 2006 Nov 1;25(21):5159-70.
First name:Nisar Peter
Last name:Malek
Acad. Title:Dr.med.
Address:OE5250Hannover Medical School
Phone and e-mail:[email protected]
Further information:http://www.mh-hannover.de/ kliniken/gastro/gastro.htm
Department and function:Director, Biophysical Chemistry
Education:1986 PhD in Biochemistry, Heidelberg University1999 Venia Legendi for Biochemistry and Biophysics,
Heidelberg University
Positions:1986 Research Associate, University of Michigan, USA1987-1990 Postdoctoral Fellow, Stanford University, USA1990-1996: Group Leader, National Institute for Medical
Research, London, UK1996-2002: Senior Group Leader, Max-Planck-Institute for
Medical Research, Heidelberg2002-: Professor of Biophysical Chemistry, MHH
Major research interests:Molecular motorsRegulation of dynamic changes in the cytoskeleton associated with cellmovements and cytokinesisG-protein mediated processes
Selected Publications:Knetsch, M.L.W., Schäfers, N., Horstmann, H., Manstein, D. J. EMBO J 2001, 20: 1620-1629.Klockow, B., Tichelaar, W., Madden, D., Niemann, H.H., Akiba, T., Hirose, K., Manstein, D.J. EMBO J 2002, 21: 240-250.Krylyshkina, O., Manstein, D.J. et al. J. Cell Biol. 2003, 161: 853-859.Reubold, T.F., Eschenburg, S., Becker, A., Kull, F.J., Manstein, D.J. Nature Struct. Biol 2003, 10: 826-830.Tsiavaliaris G, Fujita-Becker S, Manstein DJ. Nature. 2004; 427(6974):558-61.Fujita-Becker S, Durrwang U, Erent M, Clark RJ, Geeves MA, Manstein DJ. J BiolChem. 2005; 280(7):6064-71Reubold TF, Eschenburg S, Becker A, Leonard M, Schmid SL, Vallee RB, Kull FJ, Manstein DJ. Proc Natl Acad Sci U S A. 2005; 102(37):13093-8.Durrwang U, Fujita-Becker S, Erent M, Kull FJ, Tsiavaliaris G, Geeves MA, Manstein DJ. J Cell Sci. 2006; 119(Pt 3):550-8.Fujita-Becker S, Tsiavaliaris G, Ohkura R, Shimada T, Manstein DJ, Sutoh K. J BiolChem. 2006;281(47):36102-9.Fedorov R, Witte G, Urbanke C, Manstein DJ, Curth U. Nucleic Acids Res. 2006;34(22):6708-17.
First name:Dietmar
Last name:Manstein
Acad. Title:Prof. Dr.
Address:OE 4350Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:http://www.bpc.mh-hannover.de/
Department and function:Department of Pulmonary MedicineHead, Laboratory for Experimental Lung Research
Education:1996 PhD in Biology, Justus-Liebig-University Giessen
2005 Habilitation in Molecular Medicine, Justus-Liebig-UniversityGiessen
Positions:1997-1999: Post-Doc and Project Co-leader, SFB 547
“Cardiopulmonary Vascular System”, JLU Giessen1999-2004: Assistant Professor of Experimental Lung Research;
Justus-Liebig-University Giessen2005-recent: Head, Laboratory for Experimental Lung Research,
Hannover School of Medicine
Major research interests:Pathobiology of mononuclear phagocytes in acute and chronic lung
infections
Selected Publications:Holschermann H, Durfeld F, Maus U, et al. Blood 88: 3837, 1996.Maus U, v. Grote K, Kuziel WA, et al. Am J Respir Crit Care Med
166:268, 2002.Maus U, Huwe J, Ermert L, et al. Am J Respir Crit Care Med 165: 95,
2002.Maus UA, Waelsch K, Kuziel WA, et al. J Immunol 170: 3273, 2003.Maus U, Srivastava M, Paton JC, et al. J Immunol 173: 1307, 2004.Srivastava M, Jung S, Wilhelm J, et al. J Immunol 175: 1884, 2005.Maus U, Janzen S, Wall G, et al. Am J Respir Cell Mol Biol 35: 227,
2006.Srivastava M, Meinders A, Steinwede K, et al. Cell. Microbiol. 9:738,
2007.
First name:Ulrich
Last name:Maus
Acad. Title:Priv.-Doz. Dr.
Address:OE 6875Hannover School of Medicine
Phone and e-mail:[email protected]
Further information:www.mh-hannover.de/3053.html
Department and function:Professor, Senior Research Group leader
Education:1961 Dipl. chem.., University of Cologne, Germany1964 Ph.D. (Dr.rer.nat.), University of Cologne, Germany1971 Dr.rer.nat. habil., Venia legendi, University of Freiburg
i.Br. Germany Faculty of Biology
Positions:1965-67 Research Associate, Salk Institute for Biological
Studies, La Jolla, CA, USA (Fulbright Travel Scholar)1968-69 Postdoctoral Fellow, Max Planck Institute for Molecular
Genetrics, Beriln, Germany1970 Senior Research Assistant, Max Planck Institute for
Molecular Genetrics, Berlin, Germany1970 Visiting Scientist, Weizmann Institute, Rehovot, Israel1970-71 Visiting Scientist, Department of Genetics, Stanford
University Medical School, Stanford, CA1970-1980 Permanent Member, Basel Institute for Immunology,
Basel, Switzerland1980-2001 Director, Basel Institute for Immunology, Basel,
Switzerland2003- Senior Research Group Leader, Max Planck Institute for
Infection Biology, Berlin, Germany
Major research interests:The senior group will continue to work on some projects which were developed at the Basel Institute for Immunology and which have focused on the development of cells of the innate and adaptive from stem cells and early progenitors and which have studied the development of B-lymphocytes in greater details.
Selected Publications:Shimizu T, Mundt C, Licence S, Melchers F, Martensson IL. J Immunol. 2002; 168, 6286-93.Rolink AG, Schaniel C, Melchers F. Immunol Rev. 2002; 187, 87-95.Hoffmann R, Bruno L, Seidl T, Rolink AG, Melchers F. J Immunol. 2003; 170, 1339-53.Ohnishi K, Melchers F. Nat Immunol. 2003; 4, 849-56.Melchers F. Nat Rev Immunol. 2005; 5, 578-84.Melchers F, Rolink AR. Curr Top Microbiol Immunol. 2006;305:1-23.Melchers F. Immunity. 2006;25(6):864-7.
First name:Fritz
Last name:Melchers
Acad. Title:Prof. Dr.
Address:Max Planck Institute for Infection BiologyCampus Charité MitteSchumannstr. 21/2210117 Berlin, Germany
Phone and e-mail:++49-30-28460 [email protected]
Further information:http://www.mpiib-berlin.mpg.de/
Department and function:Associate Professor, Virology
Education:1990 PhD in Biology (Genetics), Eberhard Karls-University
Tübingen2002 Habilitation in Experimental Virology,
Ludwig Maximilians-University München
Positions:1991-1994: Postdoc at the Department of Virology, University
of Ulm and Department of Haematology and Oncology, University of Freiburg
1995-2001: Research Group Leader at the Department of Virology, University of Heidelberg and at the Max von Pettenkofer-InstituteLudwig-Maximilians-University München
2001-2004: Leader of the Virus-Cell-Interaction Unit at the Medical Faculty, University of Halle-Wittenberg
since 2005: Professor of Molecular Virology, Hannover Medical School
Major research interests:Analysis of viral proteins involved in the interaction of herpesviruseswith their host cellsImmunomodulation by herpesvirusesDevelopment of viral vectors for gene transfer, vaccination and tumortherapy
Selected Publications:Messerle M., Crnkovic I., Ziegler H., Hammerschmidt W., Koszinowski U.H. Proc. Natl. Acad. Sci. 1997; 94:14759-14763.Borst E., Hahn G., Koszinowski U.H., Messerle M. J. Virol. 1999; 73:8320-8329. Borst E., Mathys S., Wagner M., Muranyi W., Messerle, M. J. Virol. 2001; 75:1450-1458.Mathys S., Schroeder T., Ellwart J., Koszinowski U.H., Messerle M., Just U. J. Inf. Dis. 2003; 187:988-999.Borst E., Messerle M. Hum. Gene Ther. 2003; 14:959-970. Loewendorf A., Krueger C., Borst E., Wagner M., Just U., Messerle M. J. Virol. 2004; 78:13062-13071.Borst E., Messerle, M. J. Virol. 2005; 79(6):3615-26.Gustems M, Borst E, Benedict CA, Perez C, Messerle M, Ghazal P, Angulo A. J Virol. 2006 Oct;80(19):9899-904.
First name:Martin
Last name:Messerle
Acad. Title:Prof. Dr. rer. nat.
Address:OE 5230Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/virologie/home.html
Department and function:Group Leader Molecular Genetic Diagnostics
Education:1988-1994 Study of marine biology, University of Kiel
Main focus: marine pathology1994 Thesis at Robert Koch Institut Berlin (AIDS Zentrum)1999 PhD in cell biology, University of Kiel
Positions:1994-2000: Group Leader, Stem Cell Transplantation Unit of the II.
Medical Clinic, University of Kiel2001 Head of Molecular Genetic Diagnostics, Institute of Cell
and Molecular Pathology, Hannover Medical School
Major research interests:- Modification of steroid resistance in childhood leukemia (ALL)
by differentially expressed peptides and proteins- Mesenchymal stem cells and wnt-pathway regulation
Selected Publications:von Neuhoff N, Kaiser T, Wittke S, Krebs R, et al. Rapid Commun. Mass Spectrom2004; 18: 149-156Janke, V., von Neuhoff, N., Schlegelberger, B., Leyhausen, G., Geurtsen, W. Biomaterials. 2004; 25(19):4573-80.Ritgen M, Stilgenbauer S, von Neuhoff N, Humpe A, et al. Blood. 2004; 104:2600-2.Rudolph C, Steinemann D, von Neuhoff N, Gadzicki D, et al. Cancer Genet Cytogenet. 2004; 153(2):144-50.Cario G, Stanulla M, Fine BM, Teuffel O, Neuhoff NV, et al. Blood. 2005; 105(2):821-6.Dammann CE, Meyer M, Dammann O, von Neuhoff N. Biol Neonate. 2006; 89(2):126-32Lauten M, Schrauder A, Kardinal C, Harbott J, Welte K, Schlegelberger B, SchrappeM, von Neuhoff N. Leukemia. 2006;20(5):820-6.
First name:Nils
Last name:von Neuhoff
Acad. Title:Dr. rer. nat.
Address:OE 5120Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/zellpathologie
Department and function:Head, Biotechnology; FAL
Education:1973-1978 Veterinary Sciences, Veterinary University Hannover1978-1980 PhD thesis1985/86 Texas A&M University, College of Veterinary
Medicine1989: Habilitation Veterinary University Hannover1994: Apl. Professor for Reproductive Biology Veterinary
University Hannover
Positions:1980-1987: Scientist at the Institute for Animal Science1987-now: Head of Dept. Biotechnology at the Institute
Major research interests:Molecular regulation of preimplantation developmentTransgenesis in domestic species, Use of agricultural animals forbiomedical applications, Aspects of somatic cloningGenetic diversity
Selected Publications:Wrenzycki C, Herrmann D, Lucas-Hahn A, Korsawe K, Lemme E, Niemann H.Reprod Fertil Dev. 2005; 17(1-2):23-35.Kues WA, Carnwath JW, Niemann H. Reprod Fertil Dev. 2005;17(1-2):125-34.Yadav PS, Kues WA, Herrmann D, Carnwath JW, Niemann H. Mol Reprod Dev. 2005;72(2):182-90.Holker M, Petersen B, Hassel P, Kues WA, Lemme E, Lucas-Hahn A, Niemann H.Cloning Stem Cells. 2005;7(1):35-44.Somfai T, Dinnyes A, Sage D, Marosan M, Carnwath JW, Ozawa M, Kikuchi K, Niemann H. Theriogenology. 2006;66(2):415-22.Gebert C, Wrenzycki C, Herrmann D, Groger D, Reinhardt R, Hajkova P, Lucas-Hahn A, Carnwath J, Lehrach H, Niemann H. Genomics. 2006;88(2):222-9Kues WA, Schwinzer R, Wirth D, Verhoeyen E, Lemme E, Herrmann D, Barg-Kues B, Hauser H, Wonigeit K, Niemann H. FASEB J. 2006;20(8):1200-2.Ehling C, Rath D, Struckmann C, Frenzel A, Schindler L, Niemann H. Theriogenology. 2006;66(9):2160-4.Kues WA, Ollhoff RD, Carnwath JW, de Souza FP, Madeira HM, Niemann H. J Anim Breed Genet. 2006;123(5):326-30.Wrenzycki C, Herrmann D, Gebert C, Carnwath JW, Niemann H. Methods Mol Biol. 2006;348:285-304.Horn PA, Tani K, Martin U, Niemann H. Cloning Stem Cells. 2006;8(3):124-9Schwarzer M, Carnwath JW, Lucas-Hahn A, Lemme E, Kues WA, Wachsmann B, Haverich A, Martin U, Niemann H. Cloning Stem Cells. 2006;8(3):150-8.
First name:Heiner
Last name:Niemann
Acad. Title:Prof. Dr. med.vet. Dr.habil.
Address:Dept. BiotechnologyInstitute for Animal Science, MarienseeFAL, Hoeltystr. 1031535 Neustadt
Phone and e-mail:++49-(0)[email protected]
Further information:www.tzv.fal.de
Department and function:Department of Cellular ChemistryJunior Professor
Education:1994 PhD in Biochemistry at Lille Universiy, France
Positions:1995-1996: Postdoctoral position at University College London, UK1997-1999: Postdoctoral position at University of Dundee, UK2000: Maternity break2001: Marie Curie Fellow at Wageningen Research Center,
The Netherlands2002: Research Scientist, Cellular Chemistry, Hannover
Medical School2003- present: Junior Professor in Parasitology
Cellular Chemistry, Hannover Medical School
Major research interests:Analysis of the glycosylation pathways of eukaryotic pathogenssuch as the parasite Leishmania major and the fungus AspergillusfumigatusGalactofuranose metabolism; Nucleotide sugar transportersDesign and testing of drug leads in collaboration with other laboratories
Selected Publications:Ashikov A, Routier FH, Fuhlrott J, Helmus Y, Wild M, Gerardy-Schahn R, Bakker H. J Biol Chem 2005; 280(29), 27230-27235 Higson AP, Ross AJ, Tsvetkov YE, Routier FH, Sizova OV, Ferguson MA, NikolaevAV. Chemistry 2005, 11 (7), 2019-2030.Routier FH, Bakker H, Oelmann S, Jordi W, Lommen A, Gerardy-Schahn R, Bosch D. Glycobiology 2005: 15(2), 193-201.Tiralongo J, Ashikov A, Routier FH, Eckhardt M, Bakker H, Gerardy-Schahn R, von Itzstein M. Glycobiology 2006; 16(1), 73-81Bakker H, Kleczka B, Gerardy-Schahn R, Routier FH. Biol Chem 2005;386(7), 657-661.Kleczka B, Lamerz AC, van Zandbergen G, Wenzel A, Gerardy-Schahn R, Wiese M, Routier FH. J Biol Chem. 2007 Feb 6; [Epub ahead of print]
First name:Françoise
Last name:Routier
Acad. Title:Prof. Dr.
Address:OE 4330Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/zellulaere_ chemie
Department and function:Department of Gastroenterology, Hepatology and EndocrinologyTeam Leader
Education:1997 Medical Doctor, Georg-August-University Göttingen2003 Habilitation in Experimental Gastroenterolgy, MHH
Positions:1998-2000: Postdoc with RA DePinho:
1. Albert-Eonsytein-college of Medicine, Bronx, New York2. Dana Faber Cancer Institute, Boston, MA
2001: Research Group Leader on Senescence, Aging and Carcinogenesis funded by the Emmy-Noether-Program of the DFG
Major research interests:1. Exploring the role of telomere shortening in A) Senescence, Aging, and Regeneration and B) Induction of chromosomal instability and Cancer2. Identification of organ and tissue specific Aging Markers3. Exploring new model organisms for aging research
Selected Publications:Rudolph KL, Chang S, Millard M, Schreiber-Agus N, DePinho RA. Science 2000; 287:1253-8. Rudolph KL, Millard M, Bosenberg MW, DePinho RA. Nat Genet. 2001; 28:155-9.Wiemann SU, Satyanarayana A, Tsahuridu M, Tillmann HL, et al. FASEB J. 2002;16:935-42.Satyanarayana A, Wiemann SU, Buer J, Lauber J, et al. EMBO J. 2003; 22:4003-4013 Satyanarayana A, Greenberg RA, Schaetzlein S, Buer J, et al. MCB 2004; 24:5459-74.Schaetzlein S, Lucas-Hahn A, Lemme E, Kues WA, et al. PNAS 2004; 101:8034-8.Wiemann SU, Satyanarayana A, Buer J, Kamino K, et al. Oncogene 2005; 24(9):1501-9.Lechel A, Satyanarayana A, J u Z, Plentz RR, et al. EMBO Rep. 2005; 6(3):275-81Schaetzlein S, Rudolph KL. Reprod Fertil Dev. 2005;17(1-2):85-96.Plentz RR, Lankisch TO, Basturk M, Muller CC, Kirchhoff T, Gebel M, Bleck JS, Kubicka S, Manns MP, Meier PN, Rudolph KL. J Gastroenterol Hepatol. 2005; 20(7):1134-6.Plentz RR, Tillmann HL, Kubicka S, Bleck JS, Gebel M, Manns MP, Rudolph KL. J Gastroenterol Hepatol. 2005; 20(9):1422-8.Djojosubroto MW, Chin AC, Go N, Schaetzlein S, Manns MP, Gryaznov S, Harley CB, Rudolph KL. Hepatology. 2005; 42(5):1127-36.Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, et al. Nat Genet. 2007 Jan;39(1):99-105.
First name:K. Lenhard
Last name:Rudolph
Acad. Title:Prof. Dr. med.
Address:OE 6811Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Department and function:Junior Professor of Molecular Hematology
Education:1997 PhD in Chemistry (Biological Chemistry), Johann
Wolfgang Goethe-University in Frankfurt/Main2002 Habilitation in Molecular Biology, Hannover Medical
School
Positions:1997-1998: Post-doc at the Beckman Research Institute of the City
of Hope, Dept. of Molecular Biology1998-2002 Post-doc at the Hannover Medical School, Dept. of
Hematology and Oncology2002-current: Junior Professor of Molecular Hematology at the
Hannover Medical School, Dept. of Hematology and Oncology
Major research interests:Gene silencing mediated by RNA interference (RNAi): functionalgenomics and therapeutic optionsLentiviral gene transfer into hematopoietic stem and precursor cells
Selected Publications:Scherr M., Battmer K., Blömer U., Schiedlmeier B., Ganser A., Grez M., Eder M. Blood 2002; 99: 709-712.Scherr M., Battmer K., Ganser A., Eder M. Cell Cycle 2003; 2: 251-257.Scherr M., Battmer K., Winkler T., Heidenreich O., Ganser A., Eder M. Blood 2003;101:1566-1569.Scherr M., Battmer K., Dallmann I., Ganser A., Eder M. Oligonucleotides 2003; 13: 353-363.Scherr M., Battmer K., Schultheis B., Ganser A., Eder M. Gene Ther 2005; 12: 12-21.Eder M, Scherr M. N Engl J Med. 2005; 352(23):2446-8.Scherr M, Chaturvedi A, Battmer K, Dallmann I, Schultheis B, Ganser A, Eder M. Blood. 2006;107(8):3279-87.Venturini L, Eder M, Scherr M. J Biomed Biotechnol. 2006;2006(4):87340.Venturini L, Battmer K, Castoldi M, Schultheis B, Hochhaus A, Muckenthaler MU, Ganser A, Eder M, Scherr M. Blood. 2007 Feb 6; [Epub ahead of print]
First name:Michaela
Last name:Scherr
Acad. Title:Prof. Dr.
Address:OE 6860Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/haemonko/AK_Scherr/index1.html
Department and function:Professor, Cardiology and Angiology
Education:1984-1990 Medical School, Albert Ludwigs
University Freiburg i. Br.1987-1990 Doctoral thesis: Role of the Renin-
Angiotensin System in Experimental Heart Failure.1992-1993 Clinical Residency, Dept. of Cardiology,
Freiburg, University Hospital1993-1996 Postdoc, Dept. Of Experimental
Pathology, EMORY University Atlanta, USA.1996- Dept. Of Cardiology and Angiology, MHH
Positions:1992-1993 Clincial Residency1993-1996 Post-doc1996-1999 Clinical Residency1999-2001 Research Associatesince 2001 Assistant Prof. of Medicine
Major research interests:Vascular biology and Signal transduction of G-Protein coupledreceptors. Experimental and clinical atherosclerosis research
Selected Publications:Grote K, Drexler H, Schieffer B. Nephrol Dial Transplant. 2004; 19(4):770-3.Schieffer B, Bunte C, Witte J, Hoeper K, Boger RH, Schwedhelm E, Drexler H. J Am Coll Cardiol. 2004; 44(2):362-8Grote K, Bavendiek U, Grothusen C, Flach I, Hilfiker-Kleiner D, Drexler H, Schieffer B. J Biol Chem. 2004; 279(53):55675-81Schmidt B, Drexler H, Schieffer B. Am J Cardiovasc Drugs. 2004; 4(6):361-8.Schieffer B, Selle T, Hilfiker A, Hilfiker-Kleiner D, et al. Circulation. 2004; 110(22):3493-500Luchtefeld M, Grote K, Grothusen C, Bley S, Bandlow N, Selle T, Struber M, Haverich A, Bavendiek U, Drexler H, Schieffer B. Biochem Biophys ResCommun. 2005; 328(1):183-8.Grothusen C, Bley S, Selle T, Luchtefeld M, Grote K, Tietge UJ, Drexler H, Schieffer B. Atherosclerosis. 2005; 182(1):57-69.Grote K, Luchtefeld M, Schieffer B. Vascul Pharmacol. 2005;43(5):357-63.Grote K, Ortmann M, Salguero G, Doerries C, Landmesser U, Luchtefeld M, Brandes RP, Gwinner W, Tschernig T, Brabant EG, Klos A, Schaefer A, DrexlerH, Schieffer B. Cardiovasc Res. 2006 Aug 1;71(3):596-605.Luchtefeld M, Bandlow N, Tietge UJ, Grote K, Pfeilschifter J, Kaszkin M, Beck S, Drexler H, Schieffer B. Atherosclerosis. 2006 Oct 25; [Epub ahead of print]
First name:Bernhard
Last name:Schieffer
Acad. Title:Prof. Dr. med.
Address:OE 6880Hannover Medical School
Phone and e-mail:++49-511-532 4666++49-511-532 [email protected]
Further information:www.mh-hannover.de/ kliniken/kardiologie/htm/ home.html
Department and function:Director, Cell and Molecular Pathology
Education:1975-1982 Studied medicine at the Ludwig Maximilian University
in Munich and the Christian Albrecht University of Kiel
Positions:1983-2000 Assistant, University Lecturer, then Professor at the
Institute of Human Genetics, University of Kiel1987-2000 Deputy Director of the Institute of Human Genetics,
University of Kiel2001- Director of the Institute of Cell and Molecular
Pathology, Hannover Medical School
Major research interests:My main interests are tumor genetics, with particular emphasis on thedissection of tumorigenesis, development of new diagnostic tools, and on genetic counseling in hereditary cancer syndromes.
Selected Publications:Wilkens L, Flemming P, Gebel M, Bleck J, Terkamp C, et al. Proc Natl Acad SciUSA. 2004;101(5):1309-14. Neuhoff N, Kaiser T, Wittke S, Krebs R, et al. Rapid Commun Mass Spectrom. 2004; 18(2):149-56Zhang Y, Zeleznik-Le N, Emmanuel N, Jayathilaka N, et al. Genes Chromosomes Cancer. 2004; 41(3):257-65. Rudolph C, Steinemann D, Von Neuhoff N, Gadzicki D, et al. Cancer Genet Cytogenet. 2004; 153(2):144-50.Gadzicki D, von Neuhoff N, Steinemann D, Just M, Busche G, Kreipe H, et. al. Cancer Genet Cytogenet. 2005;159(2):164-7.Wilkens L, Gerr H, Gadzicki D, Kreipe H, Schlegelberger B. Virchows Arch. 2005; 447(3):586-92.Rudolph C, Hegazy AN, von Neuhoff N, Steinemann D, et al. Cancer Genet Cytogenet. 2005; 161(1):51-6.Rudolph C, Liehr T, Steinemann D, Emura M, Daibata M, Matsuo Y, et al. CytogenetGenome Res. 2006;112(3-4):213-21.Staal FJ, Cario G, Cazzaniga G, Haferlach T, et al. Leukemia. 2006;20(8):1385-92.Balakrishnan A, von Neuhoff N, Rudolph C, Kamphues K, et al. Genes Chromosomes Cancer. 2006;45(10):883-92Rudolph C, Bittner C, Feller AC, Merz H, Schlegelberger B. Cytogenet Genome Res. 2006;114(3-4):292-5.Gohring G, Hanke C, Kratz C, Kontny U, et al. Ann Hematol. 2006;85(12):883-5.Gadzicki D, Baumer A, Wey E, Happel CM, et al. Ann Hum Genet. 2006;70(Pt 6):958-64.
First name:Brigitte
Last name:Schlegelberger
Acad. Title:Prof. Dr..
Address:OE 5120Hannover Medical School
Phone and e-mail:++49-0511-532 [email protected]
Further information:www.mh-hannover.de/institute/zellpathologie/
Department and function:Director, Clinical ImmunologyChairman of the MD/PhD Program
Education:1976 M.D., Medical School of the Rheinische Friedrich-
Wilhelms-Universität Bonn1977 Masters of Psychology, Rheinische Friedrich-Wilhelms-
Universität Bonn
Positions:1978-83 Instructor in Medicine, Medical School of the University
of Bonn1986-94 Associate Professor of Medicine and Immunology,
Hannover Medical School1995- Head, Professor of Medicine and Immunology, Dept.
Clinical Immunology, Hannover Medical School
Major research interests:Fc receptors, regulation and activation, role in pathogenesis of diseases; activation mechanisms of human natural killer cells; pathogenesis of vasculitis and chronic rheumatoid arthritis; immunotherapy (cytokinesand immunoglobulins); immunodeficiencies, AIDS - pathogenesis and treatment; clinical therapy studies
Selected Publications:Jacobs R, et al. J Clin Immunol. 2004; 24(3):281-6Momot T, et al. Arthritis Rheum. 2004; 50(5):1561-5Stoll M, et al. Autoimmun Rev. 2004; 3(4):243-9Tillmann HL, et al. AIDS Care. 2004; 16(6):736-43Jacobs R, et al. Mol Immunol. 2005; 42(2):239-49Skokowa J, et al. J Immunol. 2005; 174(5):3041-50.Koch S, et al. Genes Immun. 2005; 6(5):445-7.Mobius U, et al. J Acquir Immune Defic Syndr. 2005; 39(2):174-80.Rihl M, et al. J Infect. 2005 Nov 4;Kumar V, et al. J Clin Invest. 2006; 116(2):512-20.Momot T, et al. J Rheumatol. 2006;33(5):1029.Kittner JM, et al. J Clin Immunol. 2006; 26(4):400-5.Konrad S, et al. Br J Haematol. 2006;134(3):345-7.Ansari AW, et al. Int Immunol. 2006;18(10):1443-51.Wendt K, et al. J Leukoc Biol. 2006; 80(6):1529-41.
First name:Reinhold Ernst
Last name:Schmidt
Acad. Title:Prof. Dr. med.
Address:OE 6830Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/kliniken/immunwww-mh-hannover.de/studium/phd
Department and function:Director, Human Genetics
Education:1966-1973 Universities of Freiburg and Basel, Medicine
Positions: 1988-1990 Professor of Human Genetics, Berlin1990- Professor of Human Genetics, Director and Chair,
MHH
Major research interests:Molecular Basis of Inherited Disease, Genetics of Behavior in Subhuman Primates, Structure and Ethics of Genetic Service Provision
Selected Publications:Rommel, Karck, Haverich, Schmidtke, Arslan-Kirchner, Hum. Mutat 2002; 20: 406Schubert S, Skawran B, Dechend F, Nayernia K, Meinhardt A, et al. Biol Reprod. 2003; 69(3):968-75.Pabst B, Arslan-Kirchner M, Schmidtke J, Miller K. Cytogenet Genome Res. 2003; 103(1-2):3-7Schmidtke J, Kuhnau W, Wand D, Edelmann J, Szibor R, Krawczak M PrenatDiagn. 2004; 24(8):662-4.Stuhrmann M, Strassburg C, Schmidtke J. Eur J Hum Genet. 2005; 13(1):69-78Krawczak M, Trefilov A, Berard J, Bercovitch F, et al. Biol Reprod. 2005; 72(5):1109-13.Singh KK, Schmidtke J. Immunogenetics. 2005; 57(3-4):289-92.Skawran B, Schubert S, Dechend F, Vervoorts J, Nayernia K, Luscher B, Schmidtke J. Mol Cell Biochem. 2005; 276(1-2):159-67.Singh KK, Ristau S, Dawson WW, Krawczak M, Schmidtke J. Exp Eye Res. 2005; 81(4):401-6.Trefilov A, Croucher PJ, Krawczak M, Schmidtke J. Twin Res Hum Genet. 2005; 8(6):551-2.Singh KK, Shukla PC, Rommel K, Schmidtke J, Arslan-Kirchner M. Eur J HumGenet. 2006;14(7):876-9.Karwacki V, Kovac J, Mauceri G, Backhaus A, Fohse L, Schmidtke J, Schubert S.Genomics. 2006;88(1):65-73.Singh KK, Rommel K, Mishra A, Karck M, Haverich A, Schmidtke J, Arslan-Kirchner M. Hum Mutat. 2006;27(8):770-7.Stuhrmann M, Nippert I, Hoy L, Schmidtke J. Clin Genet. 2006;70(1):73-7.Singh KK, Elligsen D, Liersch R, Schubert S, Pabst B, Arslan-Kirchner M, Schmidtke J. J Mol Cell Cardiol. 2007;42(2):352-6.
First name:
Jörg
Last name:
Schmidtke
Acad. Title:Prof. Dr.
Address: OE 6300Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.human-genetik.net
Department and function:Director, Virology
Education:1980 MD Mainz1986 Habilitation Innsbruck
Positions:1996 MRCPath, London, 2003 FRCPath, London, 2004- Virology, MHH
Major research interests:Kaposi‘s sarcoma – associated herpesvirus/human herpesvirus 8
Selected Publications:Greensill J, Sheldon J, Renwick NM, Beer B, Norley S, et al. J. Virol. 2000; 74:1572-1577.Luppi M, Barozzi P, Schulz TF, et al. N Engl J Med 2000; 343: 1378-1385Viejo-Borbolla A, Kati E, Sheldon J, Nathan K, Mattsson K, et al. J.Virol. 2003; 77(12):7093-100.Brinkmann MM, Glenn M, Rainbow L, Kieser A, Henke-Gendo C, Schulz TF. J Virol. 2003; 77(17):9346-58.Viejo-Borbolla A, Schulz TF. AIDS Rev. 2003; 5(4):222-9Henke-Gendo C, Schulz TF, Hoeper MM. N Engl J Med. 2004; 350(2):194-5Henke-Gendo C, Schulz TF. Curr Opin Infect Dis. 2004; 17(1):53-7Dedicoat M, Newton R, Alkharsah KR, Sheldon J, et al. J Infect Dis. 2004; 190(6):1068Viejo-Borbolla A, Pizzato M, Blair ED, Schulz TF. Virus Res. 2005;108(1-2):45-55.Viejo-Borbolla A, Thomas P, Blair ED, Schulz TF. J Gen Virol. 2005;86:2469-80.Henke-Gendo C, Mengel M, Hoeper MM, Alkharsah K, Schulz TF. Am J Respir CritCare Med. 2005; 172(12):1581-5.Viejo-Borbolla A, Ottinger M, Bruning E, Burger A, Konig R, Kati E, Sheldon JA, Schulz TF. J Virol. 2005; 79(21):13618-29.Alkharsah KR, Dedicoat M, Deluca DS, Schulz TF, Blasczyk R. Tissue Antigens. 2006; 67(2):170-2Ottinger M, Christalla T, Nathan K, Brinkmann MM, Viejo-Borbolla A, Schulz TF.J Virol. 2006;80(21):10772-86.Barozzi P, Bosco R, Vallerini D, Potenza L, Torelli G, Luppi M, Facchetti F, GuaraldiG, Schulz TF. Transplantation. 2006;82(6):851-2.Brinkmann MM, Pietrek M, Dittrich-Breiholz O, Kracht M, Schulz TF. J Virol. 2007; 81(1):42-58.Alkharsah KR, Dedicoat M, Blasczyk R, Newton R, Schulz TF. J Infect Dis. 2007; 195(6):809-16.
First name:
Thomas F.
Last name:Schulz
Acad. Title:Prof. Dr. med., FRCPath
Address:OE 5230Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Department and function:Group Leader, Transplant Laboratory
Education:1983 Degree of „Diplom-Biologe“ (Masters Degree in
Biology), University of Braunschweig
1987 Degree of „Dr.rer.nat.“ (PhD), University of Hannover
1994 Habilitation; Venia legendi for Immunology, Hannover Medical School (MHH)
Positions:1983-1987 Research Assistant, MHH
1987-1990 Research Associate, MHH
1990-1991 Fellowship of the German Research Council (DFG), National Jewish Center for Immunology, Denver
1991- Group leader, Transplant Laboratory, MHH
1999- Professor of Immunology
Major research interests:Transplant Immunology/Xenotransplantation: Analysis of human anti-pig T cell responses, development of immunomodulatory antibodies, immunological monitoring of transplant recipients.Analysis of T cell activation in the human: Signal transduction, role of cell surface molecules (CD28, CD45), CD45 polymorphisms.
Selected Publications:Siefken R, Klein-Heßling S, Serfling E, Kurrle R, Schwinzer R. J Immunol 1998; 161:1645-1651 Jacobsen M, Schweer D, Ziegler A, et al. Nature Gen 2000; 26:495-499Niemann H, Verhoeyen E, Wonigeit K et al. Transplantation 2001; 72:1898-906 Dulat H, von Grumbkow C, Baars W, Schröder N, Wonigeit K, Schwinzer R. Eur J Immunol 2001; 31: 2217-2226Schwinzer R, Witte T, Hundrieser J, et al. Genes Immun 2003; 4:168-169Bedke T, Baars W, Schwinzer R Ann Transplant. 2003; 8(3):35-8Do HT, Baars W, Schwinzer R. Transplant Proc. 2005; 37(1):51-2.Do HT, Baars W, Borns K, Windhagen A, Schwinzer R. J Immunol. 2006; 176(2):931-8.
First name:Reinhard
Last name:Schwinzer
Acad. Title:Prof. Dr.rer.nat.
Address:OE 6220Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/visceralchirurgie/
Department and function:Gastroenterology, Hepatology & EndocrinologyAttending in medicine and GI, principal investigator
Education:1977 -1985 Study of Medicine at the Ludwig-
Maximilian‘s University, Munich1985 Doctoral thesis2000 Venia legendi for international medicine
Positions:1985 - 1987 Postdoc, Dept. of Pharmacology, MHH1987 – 1988 Postdoc., Dig. Dis Center, Beth Israel Hospital, Boston1988 – 1995 Resident in Internal medicine and GI, Technical
University of Munich1995 - 2002 Attending, GI Division, Eberhard-Karls University,
Tübingen
Major research interests:1.Structure-function relationsships and protein-protein interactions in the regulation of the transport proteins for intestinal salt absorption and anion secretion.2.Mechanisms of volume regulation in gastrointestinal cells.3.Adaptive mechanisms in the gastrointestinal tract after selectiveknockout of transport and regulator proteins which are important in gastrointestinal salt and nutrient transport.
Selected publications:Bachmann O, Rossmann H, Berger UV, Colledge WH, Ratcliff R, et al. Am. J.Physiol. 2003; 284(1):G37-45.Spiegel S, Phillipper M, Rossmann H, Riederer B, Gregor M, Seidler U. Am J PhysiolGastrointest Liver Physiol. 2003; 285(5):G887-97.Fahrmann M, Kaufhold M, Pfeiffer AF, Seidler U. Br J Pharmacol. 2003; 139:545-54Spiegel S, Phillipper M, Rossmann H, Riederer B, Gregor M, Seidler U. Am J PhysiolGastrointest Liver Physiol. 2003; 285(5):G887-97Bachmann O, Riederer B, Rossmann H, Groos S, et al. Am J Physiol GastrointestLiver Physiol. 2004; 287(1):G125-33.Schwab A, Rossmann H, Klein M, Dieterich P, Gassner B, Neff C, Stock C, Seidler U. J Physiol. 2005;568(Pt 2):445-58Tuo B, Riederer B, Wang Z, Colledge WH, Soleimani M, Seidler U. Gastroenterology. 2006;130(2):349-58Bachmann O, Reichelt D, Tuo B, Manns MP, Seidler U. Am J Physiol GastrointestLiver Physiol. 2006;291(4):G650-7.Bachmann O, Heinzmann A, Mack A, Manns MP, Seidler UE. Am J PhysiolGastrointest Liver Physiol. 2006 Nov 9; [Epub ahead of print]
First name:Ursula
Last name:Seidler
Acad. Title:Prof. Dr. med.
Address:OE 6811Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/ kliniken/gastro/gastro.htm
Department and function:Institute for Transfusion Medicine
Education:1996 MD, Friedrich-Alexander-University
Erlangen2002 Medical specialist in transfusion medicine2003 W1-Professor for molecular immunohematology
Positions:1996-1998: Intern, Clinic I for Internal Medicine, Clinical Center
Fuerth1998-2001: Resident, Department of Hematology, Oncology and
Blood Bank, Humboldt-University Berlin1997-2000: Resourch Group Leader, Institute for Transfusion
Medicine, Hanover Medical School, Hanover, Germany2003-recent: W1-Professor, Institute for Transfusion Medicine,
Hanover Medical School, Hanover, Germany
Major research interests:Molecular biology of erythrocyte proteinsDecreasing Immunogenicity of Progenitor Cells by Regulating MHC Expression
Selected Publications:Seltsam A, Hallensleben M, Kollmann A, Blasczyk R. Blood 2003; 102: 3035-42.Eiz-Vesper B, Seltsam A, Blasczyk R. Transfusion 2005; 45:960-8.Seltsam A, Das Gupta C, Wagner FF, Blasczyk R. Transfusion. 2005;45:359-65.Wagner FF, Blasczyk R, Seltsam A. Transfusion 2005;45:1331-4.Figueiredo C, Seltsam A, Blasczyk R. J Mol Med. 2006;84(5):425-37.Seltsam A, Das Gupta C, Bade-Doeding C, Blasczyk R. Transfusion. 2006;46(3):434-40.Figueiredo C, Horn PA, Blasczyk R, Seltsam A. Transfusion. 2007;47(1):18-27.Seltsam A, Strigens S, Levene C, Yahalom V, Moulds M, Moulds JJ, Hustinx H, Weisbach V, Figueroa D, Bade-Doeding C, Deluca DS, Blasczyk R. Transfusion. 2007 Jan;47(1):133-46.
First name:Axel
Last name:Seltsam
Acad. Title:Prof. Dr.med.
Address:OE 8350Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www99.mh-hannover.de/institute/transfusion/transfusionsmedizin/
Department and function:Assistant Professor, Virology
Education:1982 – 1988 University of Bonn, Biology1988 – 1989 Columbia University, New York, NY, USA
Immunology1989 - 1993 European Molecular Biology Laboratory, Heidelberg,
Cell Biology
Positions:1993 - 1997 Postdoc and Staff Scientist, Yale University,
New Haven, CT, USA, Dept. Cell Biology1997 – 2002 Group leader, Biochemistry Dept., MHH
Major research interests:Our group is interested in the cell biology of complex DNA viruses. How does a virus get access to a cell, disassemble to uncover its genome for replication, and how is – within a couple of hours – the viral program switched to virus assembly and egress? We have developed several in vivo and in vitro motility assays to analyse the cell biology of Herpes Simplex Virus and particularly the microtubule-mediated capsid transport by digital video microscopy. Using these assays, we characterize cytosolic host factors as well as structural viral proteins important in HSV1 entry and egress.
Selected Publications:Sodeik, Ebersold, Helenius. J of Cell Biology 1997; 136:1007-1021.Ojala, Sodeik, Ebersold, Kutay, Helenius. Mol & Cell Biology 2000; 20:4922-4931.Döhner, Wolfstein, Prank, Echeverri, Dujardin, Vallee, & Sodeik. Molecular Biology Cell 2002; 13:2795-2809.Mabit H, Nakano MY, Prank U, Saam B, Dohner K, et al. J Virol. 2002; 76(19):9962-71Sodeik B. J Cell Biol. 2002; 159(3):393-5.Marozin S, Prank U, Sodeik B. J Gen Virol. 2004; 85(Pt 4):775-86.Haas M, Siegert M, Schurmann A, Sodeik B, Wolfes H. Biochemistry. 2004; 43(25):8152-9.Dohner K, Sodeik B. Curr Top Microbiol Immunol. 2005;285:67-108.Wolfstein A, Nagel CH, Radtke K, Dohner K, Allan VJ, Sodeik B. Traffic. 2006; 7(2):227-37Radtke K, Dohner K, Sodeik B. Cell Microbiol. 2006; 8(3):387-400.Dohner K, Radtke K, Schmidt S, Sodeik B. J Virol. 2006;80(16):8211-24.
First name:Beate
Last name:Sodeik
Acad. Title:HD Dr. rer.nat.
Address:OE 5320Hannover Medical School
Phone and e-mail:[email protected]
Further information:www.mh-hannover.de/institute/virologie/
Department and function:Professor, Human Genetics
Education:1980 – 1986 Free University Berlin, Medicine1988 MD1995 Specialist in Human Genetics2002 apl. Professorship
Positions:1987 Guestdoc, Cerrahpasha Medical Faculty,
Istanbul, Turky1988 – 1990 Postdoc, Inst. Humangenetics, FU BerlinSince 1991 Head of Molecular Diagnostics, Inst. Human
Genetics, Medical School Hannover
Major research interests:Molecular genetics of several monogenenic disorders like cysticfibrosis, haemochromatosis, morbus Osler, ataxia telangiectasia; neuro-and psychiatro-genetics, genetic screening
Selected Publications:M.Schürmann, M.Albrecht, E.Schwinger, M.Stuhrmann. Eur J Hum Genet 2002;10:729-732Groman JD, Hefferon TW, Casals T, Bassas L, Estivill X, et al. Am J Hum Genet. 2004; 74(1):176-9.Gadzicki D, Muller-Vahl KR, Heller D, Ossege S, Nothen MM, Hebebrand J, Stuhrmann M. Am J Med Genet B Neuropsychiatr Genet. 2004; 127(1):97-103Grundmann K, Laubis-Herrmann U, Dressler D, Vollmer-Haase J, et al. Mov Disord. 2004; 19(11):1294-7.Stuhrmann M, Strassburg C, Schmidtke J. Eur J Hum Genet. 2005; 13(1):69-78.Kuehl HK, Caselitz M, Hasenkamp S, Wagner S, El-Harith el-HA, Manns MP, Stuhrmann M. Hum Mutat. 2005; 25(3):320.Stuhrmann M, Hoy L, Nippert I, Schmidtke J. Genet Test. 2005;9(3):242-54.Hildebrand F, Pape HC, Griensven M, Meier S, Hasenkamp S, Krettek C, StuhrmannM. Shock. 2005;24(6):518-22.Stuhrmann M, Nippert I, Hoy L, Schmidtke J. Clin Genet. 2006;70(1):73-7El-Harith el-HA, Kuhnau W, Schmidtke J, Gadzicki D, Ahmed M, Krawczak M, Stuhrmann M. Eur J Med Genet. 2006;49(4):323-30.Metzger S, Bauer P, Tomiuk J, Laccone F, Didonato S, Gellera C, Mariotti C, Lange HW, et al. Hum Genet. 2006;120(2):285-92
First name:Manfred
Last name:Stuhrmann-Spangenberg
Acad. Title:Prof. Dr. med.
Address:OE 6300Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/humangenetik.html
Department and function:Head, ‘Clinical Reasearch Group Pseudomonas‘
Education and positions:1971 - 1976 study of biochemistry1974 - 1981 study of medicine1979 Dr. rer.nat.1984 Dr. med.1991 habilitation1992 professorship
Major research interests:• Genomics• Molecular pathology of cystic fibrosis• Pseudomonas genomics
Selected Publications:Klockgether J, Reva O, Larbig K, Tummler B. J Bacteriol. 2004; 186(2):518-34.Mekus F, Tummler B Cystic fibrosis and NOS3. Am J Respir Crit Care Med. 2004; 169(2):319-2Mekus F, Tummler B. Am J Respir Crit Care Med. 2004;169(6):770Juhas M, Wiehlmann L, Huber B, Jordan D, et al. Microbiology. 2004; 150(Pt 4):831-41.Charizopoulou N, Jansen S, Dorsch M, Stanke F, Dorin JR, Hedrich HJ, Tummler B.BMC Genet. 2004; 5(1):6.Ritzka M, Stanke F, Jansen S, Gruber AD, et al. Hum Genet. 2004;115(6):483-91.Eberl L, Tummler B. Int J Med Microbiol. 2004; 294(2-3):123-31.
Juhas M, Wiehlmann L, Salunkhe P, Lauber J, Buer J, Tummler B. FEMS MicrobiolLett. 2005; 242(2):287-95.Salunkhe P, Topfer T, Buer J, Tummler B. Bacteriol. 2005; 187(8):2565-72.Reva ON, Tummler B. BMC Bioinformatics. 2005; 14;6:251.Stanke F, Becker T, Cuppens H, Kumar V, Cassiman JJ, Jansen S, Radojkovic D, Siebert B, Yarden J, Ussery DW, Wienker TF, Tummler B. Hum Genet. 2006;:1-13van Barneveld A, Stanke F, Ballmann M, Naim HY, Tummler B. Biochim BiophysActa. 2006;1762(4):393-7.Charizopoulou N, Wilke M, Dorsch M, Bot A, Jorna H, Jansen S, Stanke F, HedrichHJ, de Jonge HR, Tummler B. BMC Genet. 2006;7:18.Reva ON, Weinel C, Weinel M, Bohm K, Stjepandic D, Hoheisel JD, Tummler B.J Bacteriol. 2006;188(11):4079-92.Bragonzi A, Wiehlmann L, Klockgether J, Cramer N, Worlitzsch D, Doring G, Tummler B. Microbiology. 2006;152(Pt 11):3261-9.Klockgether J, Wurdemann D, Reva O, Wiehlmann L, Tummler B. J Bacteriol. 2006 Dec 28; [Epub ahead of print]Chang YS, Klockgether J, Tummler B. FEMS Microbiol Lett. 2007 Feb 13; [Epubahead of print]
First name:Burkhard
Last name:Tümmler
Acad. Title:Prof. Dr. Dr.
Address:OE 6710Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www. mh-hannover.de/ kliniken/kinderheilkunde/kfg/index.htm
Department and function: Director, Cell Biology
Education:1974: Diploma in Biology from the Free University Berlin1976: PhD obtained from the Free University Berlin1977-79: EMBO Fellow at the MRC Unit for Biophysics at
King‘s College in London, UK1979-82: Postdoctoral fellow (DFG) at the Biological
Laboratories at Harvard University (Cambridge, Ma)1982-84: Heisenberg-Fellow at the LMB in Cambridge (UK)
and the Max-Planck Institute for BiophysicalChemistry in Göttingen, Germany.
Positions:1986-92: Junior-Research group leader at the Max-Planck-
Institute for Biochemistry, Martinsried, Germany1992-1998: Associate Professor at the Dept. of pathology at
Washington University St. Louis, MOsince 1998: Professor for Cell Biology at MHH
Major research interests:Intracellular vesicular transport, functions of molecular chaperones
Selected Publications:Ungewickell, E., H. Ungewickell, et al. Nature 1995; 378: 632-635.Umeda, A., A. Meyerholz, et al. Eur J Cell Biol 2000; 79(5): 336-342.Scheele, U., C. Kalthoff, et al. J Biol Chem 2001; 276(39): 36131-36138.Kalthoff, C., S. Groos, et al. Mol Biol Cell 2002; 13(11): 4060-4073.Kalthoff, C., J. Alves, et al. J Biol Chem 2002; 277(10): 8209-8216.Scheele, U., J. Alves, et al. J Biol Chem. 2003; 278(28):25357-68.Hinrichsen, L., J. Harborth, et al. J Biol Chem. 2003; 278(46): 45160-70.Tsukada M, Prokscha A, Ungewickell E, Eichele G. J Biol Chem. 2005; 280(12):11361-8.Meyerholz A, Hinrichsen L, Groos S, Esk PC, Brandes G, Ungewickell EJ. Traffic. 2005; 6(12):1225-34.Hasse S, Ungewickell EJ, Groos S. Histochem Cell Biol. 2006;126(2):219-29Hinrichsen L, Meyerholz A, Groos S, Ungewickell EJ. Proc Natl Acad Sci U S A. 2006;103(23):8715-20.Duwel M, Ungewickell EJ. Mol Biol Cell. 2006;17(10):4513-25.
First name:Ernst
Last name:Ungewickell
Acad. Title:Prof. Dr. rer. nat.
Address:OE 4130Hannover Medical School
Phone and e-mail: ++49-511- 532 [email protected]
Further information:www.mh-hannover.de/institute/zellbiologie/
Department and function:Head, Central Institute for Biophysical and BiochemicalProcedures
Education:1968-1972 Chemistry, Technical University Braunschweig1972 – 1976 Dissertation, University Hannover
Positions:1973- Hannover Medical School
Major research interests:Protein nucleic acid and protein protein interactions Single strandedDNA binding proteins, analytical ultracentrifugation, biophysicalchemistry in solution
Selected Publications:Urbanke C, Wray J. Biochem J 2001; 358:165-73 Grazulis S, Deibert M, Rimseliene R, Skirgaila R, Sasnauskas G, et al. NucleicAcids Res 2002; 30(4):876-85Meyer S, Urbanke C, Wahle E.. Biochemistry 2002 ;41(19):6082-9Landwehr M, Curth U, Urbanke C. Biol Chem 2002; 383(9):1325-33 Schubert WD, Urbanke C, Ziehm T, Beier V, Machner MP,et al. Cell 2002; 111(6):825-36Witte G, Urbanke C, Curth U. Nucleic Acids Res. 2003; 31(15):4434-40Zaremba M, Urbanke C, Halford SE, Siksnys V J Mol Biol. 2004; 336(1):81-92Dreisewerd K, Rohlfing A, Spottke B, Urbanke C, Henkel W. Anal Chem. 2004; 76(13):3482-91Hansen T, Urbanke C, Schonheit P Extremophiles 2004; 8(6):507-12Maheswaran M, Urbanke C, Forchhammer K. J Biol Chem. 2004; 279(53):55202-10Yildiz O, Doi M, Yujnovsky I, Cardone L, Berndt A, Hennig S, Schulze S, Urbanke C, Sassone-Corsi P, Wolf E. Mol Cell. 2005; 17(1):69-82.Brasen C, Urbanke C, Schonheit P. FEBS Lett. 2005; 579(2):477-82.Urbanke C, Witte G, Curth U. Methods Mol Biol. 2005;305:101-14.Zaremba M, Sasnauskas G, Urbanke C, Siksnys V. J Mol Biol. 2006;363(4):800-12.Manelyte L, Urbanke C, Giron-Monzon L, Friedhoff P. Nucleic Acids Res. 2006;34(18):5270-9.
First name:Claus
Last name:Urbanke
Acad. Title:Prof. Dr.
Address:OE 8830Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/einrichtungen/bpc/
Department and function:Head of Division of Cell Biology and Immunology, HZI
Education:1980 PhD in Cell Biology, Max-Planck-Institute for
Biophysical Chemistry, Göttingen; University Bonn1988 Habilitation in Cell Biology, University Bonn
Positions:1980-1982: Postdoc, National Cancer Institute, Bethesda,
USA (supported by EMBO fellowship)1983-1989: Research Assistant, Dept. of Biochemistry and Cell
Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen
1989-1993: Research Assistant, Project Leader in Dept. of Microbiology, HZI, Braunschweig
1994-1997: Acting head of the Division of Cell Biology and Immunology, HZI, Braunschweig
Since 1997: Full Professor (C4) for Cell Biology and Immunology, Technical University Braunschweig;Head of the Division of Cell Biology and Immunology, HZI, Braunschweig
Major research interests:Analysis of mechanisms of host/pathogen interactions signalling to the actin cytoskeleton; actin dynamics and cell motility.
Selected Publications:Lommel, S., Benesch, S., Rottner, K., Franz, T., Wehland, J. & Kühn, R. EMBO reports 2001; 2: 850-857.Schubert, W.-D., Urbanke, C., Ziehm, T., Beier, V., Machner, M., Domann, E., Wehland, J., Chakraborty, T. & Heinz, D.W. Cell 2002; 111: 825-836.Steffen, A., Rottner, K., Ehinger, J., Innocenti, M., Scita, G., Wehland, J., Stradal, T. E. EMBO J. 2004; 23(4):749-59Erck C, Peris L, Andrieux A, Meissirel C, Gruber AD, Vernet M, Schweitzer A, Saoudi Y, Pointu H, Bosc C, Salin PA, Job D, Wehland J. Proc Natl Acad Sci U S A. 2005; 102(22):7853-8.Dieterich G, Karst U, Fischer E, Wehland J, Jansch L. Nucleic Acids Res. 2006; 34(Database issue):D402-6.Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE. FEBS Lett. 2006; 580(12):455-63.Baumgartner M, Karst U, Gerstel B, Loessner M, Wehland J, Jansch L. J Bacteriol. 2007;189(2):313-24.Thedieck K, Hain T, Mohamed W, Tindall BJ, Nimtz M, Chakraborty T, Wehland J, Jansch L. Mol Microbiol. 2006;62(5):1325-39.
First name:Jürgen
Last name:Wehland
Acad. Title:Prof. Dr.
Address:Helmholtz Center forInfection Research (HZI)Braunschweig
Phone and e-mail:++49- 531- 6181 [email protected]
Further information:www.helmholtz-hzi.de
Department and function: Head, Molecular Immunology, HZI
Education:1969-1978 Biology at the Free University of Berlin,
Special Studies: Molecular Biology and Genetics1974-1978 PhD Student at the Basel Institute for Immunology,
Basel, Switzerland
Positions:1978-1980 Research Associate at the Salk Institute for Biological
Studies, Department of Developmental Biology, San Diego,USA.
1980-1983: Scientific Assistant at the Friedrich-Miescher-Laboratorium of the Max-Planck-Gesellschaft, Tübingen, Germany.
1983-1989: Member at the Basel Institute for Immunology, Basel, Switzerland.
1989-1990: Visiting Professor at the Institute for Immunology and Rheumatology, University of Oslo, Oslo, Norway.
1990-present: Group leader at the HZI (Helmholtz Center for InfectionResearch), Braunschweig, Germany.
Major research interests:Interaction of bacteria with the immune system.B cell development.
Selected PublicationsLoessner H, Weiss S Expert Opin Biol Ther. 2004; 4(2):157-68Gekara NO, Weiss S. Biochem Soc Trans. 2004; 32(Pt 5):712-4.Zelmer A, Krusch S, Koschinski A, Rohde M, Repp H, Chakraborty T, Weiss S. J Gene Med. 2005; 7(8):1097-112.Samuelsson CV, Lienenklaus S, Muller PP, Zawatzky R, Hauser H, Weiss S. BiochemBiophys Res Commun. 2005; 335(2):584-9.Gekara NO, Jacobs T, Chakraborty T, Weiss S. Cell Microbiol. 2005;7(9):1345-56.Bruder D, Nussbaum AK, Gakamsky DM, Schirle M, Stevanovic S, Singh-Jasuja H, Darji A, Chakraborty T, Schild H, Pecht I, Weiss S. Int Immunol. 2006;18(1):89-100.Loessner H, Endmann A, Rohde M, Curtiss R 3rd, Weiss S. FEMS Microbiol Lett. 2006;265(1):81-8.Jablonska J, Dittmar KE, Kleinke T, Buer J, Weiss S. Infect Immun. 2007;75(1):462-70.Becker C, Lienenklaus S, Jablonska J, Bauer H, Weiss S. J Mol Med. 2007;85(1):63-73.Loessner H, Endmann A, Leschner S, Westphal K, Rohde M, Miloud T, HammerlingG, Neuhaus K, Weiss S. Cell Microbiol. 2007 Feb 7; [E pub ahead of print]
First name:Siegfried
Last name:Weiss
Acad. Title:Dr. rer.nat.
Address:AG MolekulareImmunologie,Mascheroder Weg 1a,38124 Braunschweig
Phone and e-mail:++49-0531-6181-230, [email protected]
Further information:http://www.helmholtz-hzi.de/de/forschergruppen/molekulare_biotechnologie/molekulare_immunologie/team/personal/infos/siegfried_weiss/
Department and function:Hematology, Hemostasis and OncologyScientist (bone marrow transplantation; Experimental Hematology)
Education:1987: MD Medical Faculty, University of Vienna, Austria1997: Habilitation in Experimental Hematology, Ludwig-
Maximillians-Universität / Munich2005: APL-Professor/ Experimental Hematology
Positions:1989-1992: Visiting fellow at the National Institutes of Health, NCI, Laboratory of Genetics1992-1993: Visiting associate (NIH/NCI/LG)1993-1998: Junior group leader GSF / Hämatologikum / Munich1998-1999: Invited scientist NIH/ National Heart/Lung/Blood
Institute1999-2002: Scientific and clinical staff fellow MHH/ Hematology2002-2003: Chief medical officer mosaiques diagnostics GmbH2003- recent: Scientific group leader MHH/ Hematology
Major research interests:Gene therapy of Graft versus Host diseaseStem Cell Transplantation: experimental and clinical applicationAntigen-specific T-cells : therapeutic and researchProteomics in clinical research and diagnosis
Selected Publications:Bonini, C., Grez, M., Traversari, C., et al., Nature Med 2003; 9: 367-369Weissinger E.M., Oettrich K., Evans C., Genieser H.G., Schwede F., Dangers M., Dammann E., Kolb H.J., Mischak H., Ganser A., Kolch W. Br J Cancer 2004; 91:186-92Weissinger, E.M., Wittke, S., Kaiser, et al. Kidney Int. 2004; 65: 2426-2434Kaiser T., Kamal H., Rank A., Kolb H.J., Holler E., Ganser A., Hertenstein B., Mischak H., Weissinger E.M. Blood 2004; 104: 340-349Weissinger, E.M., Mischak, H. Transplant Med.2004; 16:1-5Weissinger EM, Oettrich K, Evans C, Genieser HG, Schwede F, Dangers M, Dammann E, Kolb HJ, Mischak H, Ganser A, Kolch W. Br J Cancer. 2004;91(1):186-92.Weissinger EM, Nguyen-Khoa T, Fumeron C, Saltiel C, Walden M, Kaiser T, Mischak H, Drueke TB, Lacour B, Massy ZA. Proteomics. 2006;6(3):993-1000.Weissinger EM, Mischak H, Ganser A, Hertenstein B. Ann Hematol. 2006;85(4):205-11Ganser A, Morgan MA, Weissinger EM. Proc Natl Acad Sci U S A. 2007; 104(4):1109-10.
First name:Eva
Last name:Mischak-Weissinger
Acad. Title:Prof. Dr.med univ.
Address:OE 6863Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/haemonko
Department and function:Director, Pediatric Hematology/Oncology
Education:1969-1973 University Tübingen, Medicine1973-1975 Freie Universität Berlin1975 Dr. med.1976 Approbation1984 Board certified Pediatrician
Positions:1985-1987 Assist. Professor, Head Laboratory of
Cytokine Biology, Memorial Sloan KetteringCenter, New York
1987-1993 Professor for Pediatrics, MHH1993-1997 Professor for Specific Pediatric Hematology
and Oncology, MHHSince 1997 Head, Dept. of Pediatric Hematology/
Oncology, MHH
Major research interests:Cytokines, Hematopoietic stem cells, Bone marrow failuresyndromes, Leukemias
Selected Publications:Ballmaier M, et al. Ann N Y Acad Sci. 2003; 996:17-25.Beger C, et al. Br J Haematol. 2003; 122(2):245-52.Lauten M, et al. Leukemia. 2003; 17(8):1551-6Lauten M, et al. Haematologica. 2003; 88(11):1253-8.Zeidler C, et al. Rev Clin Exp Hematol. 2003; 7(1):72-83.Beger C, et al. Clin Cancer Res. 2004; 10(11):3780-7.Meissner B, et al. Leukemia. 2004; 18(11):1920-3.Kracht T, et al. Haematologica. 2004; 89(12):1492-7Cario G, et al.. Blood. 2005; 105(2):821-6Cloppenborg T, et al. Leukemia. 2005; 19(1):44-8Stanulla M, et al. Blood. 2005;105(2):906-7Cario G, et al. Br J Haematol. 2005; 129(2):275-8.Wang Z, et al. Ann N Y Acad Sci. 2005; 1044:29-40.Kardinal C, et al. Blood. 2006 Feb 1;107(3):1133-40.Germeshausen M, et al. Hum Mutat. 2006; 27(3):296.Skokowa J, et al. Nat Med. 2006;12(10):1191-7.Germeshausen M, Ballmaier M, Welte K. Blood. 2007;109(1):93-9.Klein C, et al. Nat Genet. 2007;39(1):86-92.
First name:Karl
Last name:Welte
Acad. Title:Prof. Dr. med.
Address:OE 6780Hannover MedicalSchool
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/Kliniken
Department and function:Professor, Dermatology
Education:Medical Doctor, Professor of Medicine
Positions:1985-1989 Post Doc in the Dept´s of Immunology in Hannover and in Goettingen1989-1994 Clinicail Education in the the Field of Dermatology in Hannoversince 1994: Registrar („Oberarzt“) in the Dept of Dermatology
Major research interests:Dermatoimmunology:Specifity and functions of skin infiltrating T-cells in eczemaRegulation of cytokine pattern in human T-cells and antigen-presentingcellsExpression and function of anaphylatoxin receptors
Selected Publications:Gutzmer R, Lisewski M, Zwirner J, Mommert S, Diesel C, Wittmann M, Kapp A, Werfel T. Immunology. 2004;111(4):435-43.Breuer K, Heratizadeh A, Wulf A, Baumann U, Constien A, Tetau D, Kapp A, Werfel T. Clin Exp Allergy. 2004; 34(5):817-24.Breuer K, Wulf A, Constien A, Tetau D, Kapp A, Werfel T. Allergy. 2004; 59(9):988-94.Wittmann M, Alter M, Stunkel T, Kapp A, Werfel T. Allergy Clin Immunol. 2004; 114(4):965-73.Gutzmer R, Diestel C, Mommert S, Kother B, Stark H, Wittmann M, Werfel T. J Immunol. 2005; 174(9):5224-32.Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T. J Invest Dermatol. 2005; 124(6):1225-33.Breuer K, Wittmann M, Kempe K, Kapp A, Mai U, Dittrich-Breiholz O, Kracht M, Mrabet-Dahbi S, Werfel T. Clin Exp Allergy. 2005; 35(8):1088-95.Werfel T, Breuer K, Rueff F, Przybilla B, Worm M, Grewe M, Ruzicka T, Brehler R, Wolf H, Schnitker J, Kapp A. Allergy. 2006;61(2):202-5.Wittmann M, Killig C, Bruder M, Gutzmer R, Werfel T. J Leukoc Biol. 2006; 80(1):75-86.Gutzmer R, Kother B, Zwirner J, Dijkstra D, Purwar R, Wittmann M, Werfel T. J Invest Dermatol. 2006;126(11):2422-9.Purwar R, Wittmann M, Zwirner J, Oppermann M, Kracht M, Dittrich-Breiholz O, Gutzmer R, Werfel T. J Immunol. 2006;177(7):4444-50.Turjanmaa K, Darsow U, Niggemann B, Rance F, Vanto T, Werfel T. Allergy. 2006; 61(12):1377-84.Langer K, Breuer K, Kapp A, Werfel T. Exp Dermatol. 2007 Feb;16(2):124-9.
First name:Werfel
Last name:Thomas
Acad. Title:Prof Dr. med.
Address:Dept DermatologyHannover Medical SchoolRicklinger Str. 530449 Hannover
Phone and e-mail:[email protected]@gmx.de
Further information:http://www.klinikum-hannover.de/hkl/
Department and function:Juniorprofessor, Dermatology
Education:1989 Abitur, Gymnasium am Geroweiher,
Mönchengladbach1989-96 University Studies, Human Medicine, Heinrich-Heine
University, Düsseldorf
Positions:1996 – 2003 Residency, Department of Dermatology, Hannover
Medical School1999-2001 Postdoctoral Research (DFG Grant)12/2002 - Juniorprofessor, Department of Dermatology,
Hannover Medical School
Major research interests:Inflammation in eczematous skin diseases, regulation of IL-12, Th1 / Th2 „specific“ transcription factors, heat shock proteins in inflammatory skin diseases (HSP70, HSP27, gp96)
Selected Publications:Wittmann et al. Blood 1999; 94:1717Wittmann et al. Int Arch Allergy Immunol 2001; 124:346Wittmann et al. J Immunol 2002; 168:3793Gutzmer R, Langer K, Mommert S, Wittmann M, Kapp A, Werfel T. J Immunol. 2003; 171(12):6363-71.Gutzmer R, Lisewski M, Zwirner J, Mommert S, Diesel C, Wittmann M, Kapp A, Werfel T. Immunology. 2004; 111(4):435-43Wittmann M, Alter M, Stunkel T, Kapp A, Werfel T. J Allergy Clin Immunol. 2004; 114(4):965-73Wittmann M, Purwar R, Hartmann C, Gutzmer R, Werfel T. J Invest Dermatol. 2005; 124(6):1225-33.Purwar R, Werfel T, Wittmann M. J Invest Dermatol. 2006;126(5):1043-51.Wittmann M, Killig C, Bruder M, Gutzmer R, Werfel T. J Leukoc Biol. 2006; 80(1):75-86Purwar R, Wittmann M, Zwirner J, Oppermann M, Kracht M, Dittrich-Breiholz O, Gutzmer R, Werfel T. J Immunol. 2006;177(7):4444-50.Purwar R, Werfel T, Wittmann M. J Invest Dermatol. 2007 Jan 18; [Epub ahead of print]
First name:Miriam
Last name:Wittmann
Acad. Title:Prof. Dr. med.
Address:Ricklinger Str. 530449 Hannover
Phone and e-mail:0511 9246 278miriamwittmann@ web.de
Further information:http://www.klinikum-hannover.de/hkl/
Department and function:Head, "In Vitro Differentiation" Group, IPK Gatersleben
Education:1964-1969 Study of biology at the Univ. of Greifswald1970-1974 PhD thesis at the Institute of Genetics Gatersleben /
University of Halle1997 Habilitation and venia legendi ("Cell Biology") at the
Medical Faculty, University of Halle
Positions:1974-1991 Scientific co-worker (Mutagenesis and embryonic
stem cell research) Institute of Genetics, Gatersleben, Academy of Sciences
Since 1992 Head of the Research Group "In Vitro Differentiation", IPK Gatersleben
Major research interests:-Stem cell research: Embryonic and adult (intestinal, hematopoietic) stem cells-Stem cell differentiation into cardiac, skeletal, vascular smooth muscle, neuronal and pancreatic cells-Analysis of cell-cell and cell-matrix interactions-Embryotoxicity analysis in vitro using embryonic stem cells
Selected Publications:Czyz J, Nikolova T, Schuderer J, Kuster N, Wobus AM. Mutat Res. 2004; 557(1):63-74.Rolletschek A, Blyszczuk P, Wobus AM.Toxicol Lett. 2004;149(1-3):361-9. Kania G, Blyszczuk P, Wobus AM. Int J Dev Biol. 2004; 48(10):1061-4.Kania G, Blyszczuk P, Jochheim A, Ott M, Wobus AM. Biol Chem. 2004; 385(10):943-53Blyszczuk P, Asbrand C, Rozzo A, Kania G, St-Onge L, Rupnik M, Wobus AM.. Int J Dev Biol. 2004;48(10):1095-104.Czyz J, Guan K, Zeng Q, Wobus AM. Int J Dev Biol. 2005;49(1):33-41.Kania G, Corbeil D, Fuchs J, Tarasov KV, Blyszczuk P, Huttner WB, Boheler KR, Wobus AM. Stem Cells. 2005;23(6):791-804.Nikolova T, Czyz J, Rolletschek A, Blyszczuk P, Fuchs J, Jovtchev G, Schuderer J, Kuster N, Wobus AM. FASEB J. 2005;19(12):1686-8.Wiese C, Rolletschek A, Kania G, Navarrete-Santos A, Anisimov SV, Steinfarz B, Tarasov KV, Brugh SA, et al. Stem Cells. 2006;24(9):2085-97.Wiese C, Kania G, Rolletschek A, Blyszczuk P, Wobus AM. Methods Mol Biol. 2006;325:181-205Blyszczuk P, Wobus AM. Methods Mol Biol. 2006;330:373-85.Rolletschek A, Kania G, Wobus AM. Diabetologia. 2006;49(11):2541-5.Schroeder IS, Kania G, Blyszczuk P, Wobus AM. Methods Enzymol. 2006;418:315-33.
First name:Anna M.
Last name:Wobus
Acad. Title:PD Dr. rer. nat.
Address:Institute of Plant Genetics (IPK Gatersleben)Corrensstr. 306466 Gatersleben
Phone and e-mail:[email protected]
Further information:www.ipk-gatersleben.de