mcgill university price list · (ltm™) support team phone: 1.781.222.6701 email:...

RESEARCH MODELS AND SERVICES 2018

McGill University Price List

Research Models and ServicesWhat began as a thousand cages in a warehouse in Boston is now a global network of comprehensive research facilities that are strategically

positioned to support your research in all major therapeutic areas. Through vital husbandry and study support, as well as supplementary staffi ng, consulting,

training, and equipment, we fi ll the gaps so you can focus on your research. Our portfolio includes:

Further downstream, we help you maintain momentum on the way to market by shepherding your drug through discovery, safety assessment, clinical

development, and manufacturing. Visit www.criver.com to explore how we can help streamline your operations throughout the course of research.

MORE THAN A MOUSE

• Research Animal Models

• Biospecimens

• Animal Health Monitoring

• Surgical Services

• Animal Colony Management

• Embryology Services

• Preconditioned Models

• Model Creation Services

• Genetic Testing Services

• Clinical Pathology and Biomarkers

1.877.criver1 | www.criver.com | [email protected]

Customer Support CenterPhone: 1.877.CRIVER1 (1.877.274.8371)Email: [email protected]

Our expert technical group, including our highly qualifi ed professional staff of veterinarians and doctorate-level scientists, can assist you in areas such as laboratory animal science, biology, husbandry, surgery, and health issues.

Specifi cally, we can assist you with:

• Information regarding the Charles River portfolio

• Performing literature searches

• Answering questions about specifi c animal models

• Coordinating custom orders, including surgical procedures and genetically modifi ed or preconditioned research models

Research Models Customer Service DepartmentPhone: 1.800.561.4975Fax: 1.450.638.6700

Our customer service representatives strive to make the research model order and shipment process as easy as possible for you. Our customer service representatives can help you with product information as well as pricing and shipping details. We offer three ways for you to order research models: phone, fax, and mail.

Specifi cally, we can assist you with:

• Animal orders

• Model availability

• Pricing and shipping details

Laboratory Services Client Relations/ Laboratory Testing Management® (LTM™) Support TeamPhone: 1.781.222.6701Email: [email protected]

The Laboratory Services Client Relations team is your resource for health and genetic testing, including the use of LTM™, our online, interactive order entry and results management system that centralizes your health and genetic testing programs into one virtual location. For more information on LTM™, visit www.criver.com/ltm.

The Client Relations team can assist you with:

• Online ordering, scheduling sample submission, and sample shipping

• Coordinating delivery of your complimentary shipping materials

• Results retrieval and interpretation

• One-on-one or group demonstrations and training on LTM™

• Pricing, quotes, and invoice questions

If you are unsure about whom to contact at Charles River, we recommend that you start with our Customer Support Center. Our representatives are available from 6 a.m.–6 p.m. ET Monday through Friday to fi eld any questions you may have, or to direct inquiries to the correct contact or department. For all correspondence: Laboratoires Charles River St-Constant, 324 Rang St-Régis Nord, St-Constant, Québec J5A 2E7

CONTACT US


Our Animal ModelsCharles River is committed to providing you with high-quality genetically standardized models such as VAF/Plus® and VAF/Elite® animals which are free of select infectious agents and parasites. We understand that selecting the appropriate animal model for your studies is critical to your research success. To assist you, we offer an evaluation program that allows you to assess the quality and compatibility of our animal models before making a purchase. For more information, please go to www.criver.com/rmeval.

VAF* Health Profi lesThe table below lists the infectious agents specifi cally excluded from our VAF/Plus®, VAF/Elite®, and Immunodefi cient VAF/Elite® animal colonies. For further information regarding viral profi les, microbiological fl ora, or the comprehensive list of agents included in the Charles River health surveillance program, please go to the Health Reports section of our website at www.criver.com/info/rm or contact us at 1.877.274.8371 or [email protected].

Health Profi le Species Agents Excluded†

VAF/Plus®

Mouse

SEND, PVM, MHV, MVM, MPV, TMEV (GDVII), REO, EDIM, MAV, POLY, K, MCMV, MTLV, LCMV, HANT, ECTRO, ECUN, CARB, LDV, MNV

M. pulmonis, Salmonella spp., S. moniliformis, C. kutscheri, H. hepaticus, C. rodentium

RatSEND, PVM, SDAV, KRV, H-1, RPV, RMV, REO, RTV, LCMV, HANT, MAV, ECUN, CARB

M. pulmonis, Salmonella spp., S. moniliformis, C. kutscheri, H. hepaticus

Guinea pigSEND, PVM, LCMV, REO, GAV

M. pulmonis, Salmonella spp., S. moniliformis, S. zooepidemicus, B. bronchiseptica, H. hepaticus

HamsterSEND, PVM, LCMV, REO, ECUN

Salmonella spp., H. hepaticus

RabbitECUN, RHDV

P. multocida, Salmonella spp., Treponema, Tyzzer’s disease

VAF/Elite®

Mouse (immunocompetent)

These mice are free of all of the agents listed above in the VAF/Plus® mouse profi le, plus Beta hemolytic Streptococcus spp., K. oxytoca, K. pneumoniae, P. pneumotropica, P. aeruginosa, P. mirabilis, S. aureus.

Mouse (immunodefi cient)

These mice are free of all of the agents listed above in the VAF/Plus® mouse profi le, plus Beta hemolytic Streptococcus spp., K. oxytoca, K. pneumoniae, P. pneumotropica, Pneumocystis spp., P. aeruginosa, P. mirabilis, S. aureus, C. bovis.

Rat (immunodefi cient)

These rats are free of all of the agents listed above in the VAF/Plus® rat profi le, plus S. aureus, S. pneumoniae, Beta hemolytic Streptococcus spp., Klebsiella spp., K. oxytoca, K. pneumoniae, P. pneumotropica, Pneumocystis spp., P. aeruginosa, P. mirabilis, C. bovis.

* Virus Antibody Free (VAF)† All helminths, ectoparasites, and pathogenic GI protozoa are excluded as part of our VAF/Plus® and VAF/Elite® profi les. See Glossary of Terms for abbreviation key for agents.

The VAF/Elite® health profi le is currently offered for the following stocks and strains of mice: 129-Elite, BALB/c-Elite, C57BL/6-Elite, CD1-Elite, SJL-Elite, and SKH1-Elite.

RESEARCH MODELS


Birth DatesBirth dates are furnished on shipping documents and are calculated according to the ship date of the order. The date of birth is based upon the midpoint of the specifi ed age range. Exact date of birth is provided when exact-age animals are ordered.

Age/Weight Correlation InformationAge/weight correlation information is presented throughout this product catalog for each sex of most stocks and strains. The information is specifi c to the conditions maintained in Charles River barrier production rooms. The shaded areas on each chart are the mean weight, plus or minus two standard deviations, at a given age, averaged across all production facilities. This represents the majority of the population. Overlaps in the full range of weights occur between age groups and will be more pronounced in outbred animals.

Ordering Information To accommodate your need for prompt shipment, sales are made on the basis of telephone orders without written documentation. Fax or email confi rmation of orders are available upon request. Our acceptance of your order is expressly made conditional on your consent to our General Terms and Conditions of Sale, and our prices have been set accordingly.

Any provision of a purchase order or confi rmation that is additional to or confl icts with our General Terms and Conditions of Sale is expressly rejected and shall not be binding on us. Please consider this before placing your order.

Some animal models are produced only in small quantities. Upon your request, we will work to scale up our colony production to meet your needs.

The prices in this catalog are for customers located in the Canada who are purchasing research models and services sourced from Canada. All other customers should contact Customer Service for pricing in your region.

For additional information, please contact the Customer Service Department at 1.800.561.4975 or by fax at 1.450.638.6700.

Cancellation PoliciesStandard or Regular Animal Orders To avoid charges, cancellation of standard animal orders must be received one business day prior to the scheduled shipment date.

Rabbit Orders Cancellations of rabbit orders shipping at 3.1 kg or higher are subject to a cancellation fee.

Timed Pregnant Animals To avoid charges, cancellations for pregnant animals must be received prior to the scheduled mating day.

Value-Added Services To avoid charges, cancellations for value-added services, including, but not limited to, tattooing or ear tagging, must be received at least three business days prior to the ship date.

Surgical and Biospecimen Services Cancellations must be received at least fi ve business days prior to the scheduled ship date for most orders. Notice of cancellation is extended prior to the scheduled ship date for procedures with prolonged holding times, including, but not limited to, 5/6 nephrectomy, Parkinson’s, and telemetry procedures. Animals requested to be held longer than seven days postoperatively will incur a holding fee.

Shipments Outside North America Cancellations need to be received by 5:00 p.m. Eastern Time (ET) on the Friday prior to shipping. If canceled by then, the only cost incurred is for the USDA Health Certifi cate. If cancellation notice is received after the animals are packed and/or sent to the airport, the customer is responsible for animal and freight charges for transportation to/from the airport.

Miscellaneous ChargesSurcharges (where applicable)

1 gram weight range for inbred mice Add 5%

5 gram weight range for non-obese rats & hamsters Add 25%

10 gram weight range for non-obese rats Add 15%

Retired breeders with specifi ed weight or approximate age Add 50%

Applicable Container and Other Charges

Filtered shipping container (Sew Easy™) 19.75 each

Gnoto-safe® shipping container 38.60 each

Rabbit shipping container 21.75 each

Weight list 0.60 per animal

Import/Export Preparation Charges

Preparation of appropriate documentation for international shipment of Charles River products

570.00per shipment*

Importation or exportation of non-Charles River products

870.00 per shipment*

* Plus fi xed costs

Pregnant Animal Guarantee PolicyCharles River produces pregnant animals to your order specifi cation. Most barrier-reared rats and mice can be safely and accurately palpated for pregnancy after 13 days of gestation. Prior to that, pregnancy is determined by observation of a vaginal plug. Following timed exposure to the male, the date the copulatory plug is found (plug date) is considered to be day zero of gestation. For additional information and/or strain availability, contact the Customer Service Department at 1.800.561.4975.

PERCENT GUARANTEED PREGNANT

Stock or Strain

Timed Pregnant Up to 12 Days Gestation

Timed Pregnant 13

Days Gestation and Over

Untimed Pregnant

13-17 Days Gestation Only

Outbred rats 90% 100% 100%

Outbred mice 75% 100% 100%

Inbred and specialty rats, inbred and specialty mice

Plugguarantee

only75% 75%

NZW rabbits 50% 100% N/A

Note: We do not guarantee the number of offspring per litter. Due to natural variation in the length of gestation, the exact day of parturition is not guaranteed. To avoid charges, cancella-tions for pregnant animals must be received prior to the scheduled mating day.


RatsGram Range Non-Obese

Days Range Non-Obese

Days Range Obese

Animals perContainer*

Up to 50 Up to 21 Up to 21 20

51-75 22-26 22-24 17

76-100 27-30 25-26 13

101-125 31-35 27-28 10

126-150 36-42 29-36 9

151-200 43-50 37-42 8

201-250 51-60 43-48 6

251-300 61-70 49-56 5

301-400 71-94 57-63 4

401-450 95-plus 64-70 3

451-plus 71-plus 2

* Number of animals per container may be reduced as needed based on model requirements.

MiceGram Range Non-Obese

Days Range Non-Obese

Days Range Obese

Animals per Container

Up to 35 Up to 56 Up to 56 40

36-plus 57-plus 57-70 33

71-plus 20

RabbitsKilogram Range Animals per Container

Up to 2.5 2

2.6-plus 1

Guinea PigsGram Range

Days Range


Up to 350 Up to 33 10

351-600 34-65 6

601-800 66-81 5

801-plus 82-plus 4

GerbilsGram Range

Days Range

Animals per Con-tainer

Up to 35 Up to 35 35

36-50 36-56 25

51-70 57-84 20

71-plus 85-plus 15

HamstersGram Range

Days Range


Up to 50 Up to 21 25

51-70 22-42 20

71-plus 43-plus 15

100% Recyclable Gnoto-safe®

Shipping ContainerMice Rats

Animals per container* 30 2

* Two cages per container

Special Services Rats per

ContainerMice per Container

Guinea Pigs per Container

Hamsters per Container

Retired breeders 3 33 2 3

Proven breeders 3 33 2 3

Timed pregnants 7 17 3 3

Untimed pregnants 7 17 3 3

Littermates 7 (1 litter) 7 (1 litter) 3 (1 litter) 10 (1 litter)

Mothers with pups 2 3 2 2

Lactating females 7 33 3 15

Filtered (Sew Easy™) Shipping Container DensitiesIt is our responsibility to maintain the strictest health and welfare standards when shipping our animals, not only because it’s the right thing to do but because our animals are vital to your research. To help make the comfort and care of our animals a priority, we provide several crates that are tailored to established shipping density guidelines for a variety of species. Our shipping

crates have viewing windows that allow you to inspect the animals and assess their interior conditions during and after shipping. The interior of our fi ltered crates is UV light irradiated prior to packing animals, and our individual Gnoto-safe® plastic containers are disinfected with a cold sterilant prior to packing the animals.

www.criver.com CHARLES RIVER RESEARCH MODELS AND SERVICES | US 2018

Filtered shipping container (Sew Easy™) 20.30 Filtered shipping container (Sew Easy™) 20.30Gnoto-safe™ shipping container 38.20 Gnoto-safe™ shipping container 38.20

Air Freight 269.50 Air Freight 269.50Truck Freight 44.00 Truck Freight 44.00Local Truck Freight 15.35 Local Truck Freight 7.68 50% discountRabbit Air Freight 269.50 Rabbit Air Freight 269.50

Unless otherwise stated, the following McGill University pricing reflects a 0% discount off of the 2018 published Charles River research models and services price list.

2018 CHARLES RIVER LIST PRICE 2018 CUSTOMER PRICE

Crate Charges

Freight Charges

CRATE & FREIGHT


CD® IGS Rats when ordering, specify CDSTRAIN CODE: 001

Weight in Grams Material# Price Material# Price Weight in Grams

Up to 50 24100527 17.45 24100503 17.45 Up to 50

51-75 24100528 20.80 24100504 21.60 51-7576-100 24100529 24.45 24100505 25.40 76-100

101-125 24100530 27.50 24100506 27.95 101-125

126-150 24100531 29.40 24100507 31.05 126-150

151-175 24100532 31.50 24100508 32.75 151-175

176-200 24100533 34.65 24100509 36.35 176-200

201-225 24100534 37.00 24100510 38.85 201-225

226-250 24100535 40.40 24100511 42.10 226-250

251-275 24100536 45.05 24100512 45.45 251-275

276-300 24100537 46.70 276-300

301-325 24100538 49.20 301-325

326-350 24100539 55.00 326-350351 plus 351 plus

Retired breeders 24100584 35.55 24100583 34.15 Retired breedersLittermates 21 days old only 24100580-21 27.70 24100580-21 27.70 Littermates 21 days old only

Lactating rat with litter 24100577-1 142.30 Lactating rat with litterTimed pregnant* 24100552 136.40 Timed pregnant*

Untimed pregnant* 24100574 112.90 Untimed pregnant* For timed and untimed pregnant, please see our pregnant animal guarantee policy. * For timed and untimed pregnant, please see our pregnant animal guarantee policy.

Sprague Dawley® Rats when ordering, specify SAS SDSTRAIN CODE: 400

Weight in Grams Material# Price Material# Price Weight in GramsUp to 50 24104812 16.70 24104792 16.30 Up to 5051-75 24104813 19.15 24104793 20.00 51-7576-100 24104814 22.45 24104794 23.85 76-100101-125 24104815 25.75 24104795 26.10 101-125126-150 24104816 27.70 24104796 30.45 126-150151-175 24104817 31.30 24104797 33.30 151-175176-200 24104818 34.90 24104798 36.70 176-200201-225 24104819 38.95 24104799 39.85 201-225226-250 24104820 41.65 24104800 42.80 226-250251-275 24104821 43.70 251-275276-300 24104822 47.50 276-300301-325 24104823 49.55 301-325326-plus 326-plus

Retired Breeder 24104868 34.95 24104867 34.25 Retired BreederLittermates (21 days old only) 24104864-21 19.90 24104864-21 19.90 Littermates (21 days old only)

Lactating Rat with Litter 24104863-1 115.05 Lactating Rat with LitterTimed Pregnant* 24104838 110.80 Timed Pregnant*

Untimed Pregnant* 24104860 88.65 Untimed Pregnant*

112.90

Prices upon request

40.40

45.05

46.70

49.20

55.00

35.55

Price Price

20.0023.8526.1030.45

110.80

19.90115.05

34.9519.90

32.75

36.35

38.85

42.10

45.45

34.1527.70142.30136.40

2018 CUSTOMER PRICE

Prices upon request

FEMALE FEMALE MALEMALE

Prices upon requestPrices upon request

17.45

20.8024.45

27.50

29.40

31.50

34.65

37.00

Price

17.45

21.6025.40

27.95

31.05


MALE FEMALE MALE FEMALE

33.30

16.7019.1522.4525.7527.7031.30

27.70

Price

36.7039.8542.80

2018 CHARLES RIVER LIST PRICE

* For timed and untimed pregnant SAS SD rats, determination of pregnancy is by observation of vaginal plug. Plug date is considered to be day zero of gestation. Please see our pregnant animal guarantee policy.

16.30

34.9038.9541.6543.7047.5049.55

34.25

88.65* For timed and untimed pregnant SAS SD rats, determination of pregnancy is by observation of vaginal plug. Plug date is considered to be day zero of gestation. Please see our pregnant animal guarantee policy.

OUTBRED RATS


CD® Hairless RatsSTRAIN CODE: 184

Age in Days* Material# Price Material# Price Age in Days*

Up to 21 24102743 61.40 24102717 61.40 Up to 21

22-28 24102744 66.60 24102718 66.60 22-28

29-35 24102745 70.60 24102719 70.60 29-35

36-42 24102746 75.40 24102720 75.40 36-42

43-49 24102747 79.45 24102721 79.45 43-4950-56 24102748 85.45 24102722 85.45 50-5657-63 24102749 91.20 24102723 91.20 57-6364-70 24102750 96.80 24102724 96.80 64-7071-77 24102751 105.95 24102725 105.95 71-7778-84 24102752 114.70 24102726 114.70 78-84

85 Plus 85 PlusRetired breeders 24102769 72.30 24102768 71.55 Retired breeders

Lactating rat with litter 24102767 285.45 Lactating rat with litterUntimed pregnant† 24102766 246.75 Untimed pregnant†

*Estimated age *Estimated age† For untimed pregnant, please see our pregnant animal guarantee policy. † For untimed pregnant, please see our pregnant animal guarantee policy.

Long-Evans RatsSTRAIN CODE: 006

Weight in Grams Material# Price Material# Price Weight in GramsUp to 50 24100880 17.30 24100850 17.30 Up to 5051-75 24100881 20.70 24100851 21.40 51-7576-100 24100882 24.30 24100852 25.30 76-100101-125 24100883 27.30 24100853 27.95 101-125126-150 24100884 29.25 24100854 30.55 126-150151-175 24100885 31.30 24100855 32.20 151-175176-200 24100886 34.10 24100856 35.80 176-200201-225 24100887 36.65 24100857 38.50 201-225226-250 24100888 40.05 24100858 41.65 226-250251-275 24100889 44.65 24100859 45.00 251-275276-300 24100890 46.25 276-300301-325 24100891 48.55 301-325326 plus 326 plus


Lactating rat with litter 24100935 141.45 Lactating rat with litterTimed pregnant* 24100910 131.85 Timed pregnant*

Untimed pregnant* 24100932 112.15 Untimed pregnant*

* For timed and untimed pregnant, please see our pregnant animal guarantee policy. * For timed and untimed pregnant, please see our pregnant animal guarantee policy.

Sentinel Rats (Isolator-Maintained)STRAIN CODE: 118

Age in Days* Material# Price Age in Days*

28-42 24102499 40.20 28-42*Estimated age *Estimated age

131.85112.15

35.8036.65 38.5040.05 41.65

45.0046.2544.65

35.2527.50

Prices upon request33.9527.50141.45

17.3020.70 21.4024.30 25.3027.30 27.95

30.5531.30 32.20

Price

285.45



FEMALE

Prices upon request

96.80105.95114.70

71.55

246.75

FEMALE

Price

61.40

96.80105.95114.70

66.60

70.60

75.40

79.4585.45

Prices upon request72.30

FEMALE

Price

40.20

FEMALE

Prices upon request

Price

29.25

48.55

MALE FEMALE MALE

17.30

34.10

66.60

70.60

75.40

79.4585.4591.20

MALE

Price

61.40

FEMALE MALE

91.20

OUTBRED RATS


Wistar IGS RatsSTRAIN CODE: 003

Weight in Grams Material# Price Material# Price Weight in GramsUp to 50 24100704 17.45 24100674 17.45 Up to 5051-75 24100705 20.90 24100675 21.65 51-7576-100 24100706 24.55 24100676 25.50 76-100101-125 24100707 27.60 24100677 28.20 101-125126-150 24100708 29.55 24100678 30.90 126-150151-175 24100709 31.65 24100679 32.45 151-175176-200 24100710 34.45 24100680 36.20 176-200201-225 24100711 37.00 24100681 38.85 201-225226-250 24100712 40.40 24100682 42.10 226-250251-275 24100713 45.05 251-275276-300 24100714 46.70 276-300 301-325 24100715 49.20 301-325 326 plus 326 plus


Lactating rat with litter 24100754-1 142.80 Lactating rat with litterTimed pregnant 24100729 133.15 Timed pregnant

Untimed pregnant 24100751 113.25 Untimed pregnant

STRAIN CODE: 273

Weight in Grams Material# Price Material# Price Weight in Grams

Up to 50 24103513 18.45 24103487 18.50 Up to 5051-75 24103514 23.50 24103488 25.45 51-7576-100 24103515 28.55 24103489 30.30 76-100101-125 24103516 33.30 24103490 34.65 101-125126-150 24103517 36.35 24103491 40.10 126-150151-175 24103518 38.00 24103492 42.75 151-175176-200 24103519 43.10 24103493 46.85 176-200201-225 24103520 47.35 24103494 50.25 201-225226-250 24103521 52.35 226-250251-275 24103522 55.25 251-275276-300 24103523 58.05 276-300301-325 24103524 62.75 301-325326 plus 326 plus


Lactating rat with litter 24103563-1 161.85 Lactating rat with litterTimed pregnant 24103538 150.90 Timed pregnant

Untimed pregnant 24103560 126.30 Untimed pregnant 126.30

55.2558.0562.75

45.45 43.7534.50 34.50

161.85

38.00 42.7543.10 46.8547.35 50.2552.35

150.90

18.45 18.5023.50 25.4528.55 30.3033.30 34.6536.35 40.10

34.2527.80142.80133.15113.25

Price Price

40.4045.05

FEMALE

46.70

Price17.4521.6525.5028.2030.9032.4536.2038.8542.10

Price17.4520.9024.55


Prices upon request Prices upon request

MALE FEMALE

MALE FEMALE


MALE FEMALE

Wistar Han IGS Rats


MALE

49.20

27.6029.5531.6534.4537.00

35.5527.80

OUTBRED RATS


Material# Price Material# PriceUp to 21 24109686 48.25 24109665 49.00 Up to 2122-28 24109687 48.25 24109666 49.00 22-2829-35 24109688 55.00 24109667 61.65 29-3536-42 24109689 67.05 24109668 74.40 36-4243-49 24109690 76.90 24109669 90.00 43-4950-56 24109691 93.70 24109670 90.00 50-5657-63 24109692 97.50 24109671 105.15 57-6364-70 24109693 110.75 24109672 105.15 64-7071-77 24109694 117.30 24109673 135.70 71-77

78 plus 78 plusRetired breeders 24109743 53.30 24109742 51.30 Retired breeders

Littermates 21 days old only 24109739-21 54.60 24109739-21 54.60 Littermates 21 days old onlyLactating rat with litter 24109736 306.05 Lactating rat with litter

Timed pregnant 24109711 255.05 Timed pregnantUntimed pregnant 24109733 234.05 Untimed pregnant

*Estimated age *Estimated age

Material# Price Material# PriceUp to 21 24109603 32.65 24109582 33.25 Up to 2122-28 24109604 33.80 24109583 36.80 22-2829-35 24109605 41.75 24109584 40.35 29-3536-42 24109606 49.90 24109585 49.40 36-4243-49 24109607 54.60 24109586 55.20 43-4950-56 24109608 61.45 24109587 66.05 50-5657-63 24109609 65.30 24109588 66.05 57-63


Littermates 21 days old only 24109651 51.00 24109651 51.00 Littermates 21 days old onlyLactating rat with litter 24109648 270.30 Lactating rat with litter








54.6061.4565.30

270.30219.70197.70

48.2551.00

33.2536.8040.3549.4055.2066.0566.05

47.2551.00

117.30

53.3054.60

Price

51.3054.60306.05255.05234.05

Prices upon request

Price

Price48.2548.2555.0067.0576.9093.7097.50110.75

Price49.0049.0061.6574.4090.0090.00105.15105.15



MALE FEMALE

Brown Norway Rats when ordering, specify BNSTRAIN CODE: 091

Fischer Rats when ordering, specify CDF ™

STRAIN CODE: 002

FEMALE MALE

Age in Days* Age in Days*

MALE FEMALE


30.60 31.4532.75 34.8537.30 34.85

Age in Days*Age in Days*

MALE FEMALE


32.6533.8041.7549.90

F344 Rats when ordering, specify SAS FISCHSTRAIN CODE: 403

Age in Days*

MALE FEMALE

Age in Days*

MALE FEMALE

Price Price

41.50 39.3047.30 44.9559.25 50.3061.10 50.30


129.20104.70

44.00 42.7569.85 69.85

270.65

INBRED RATS


Material# Price Material# PriceUp to 21 24109517 36.45 24109496 35.25 Up to 2122-28 24109518 41.45 24109497 40.05 22-2829-35 24109519 46.40 24109498 45.35 29-3536-42 24109520 49.05 24109499 50.25 36-4243-49 24109521 59.50 24109500 57.90 43-4950-56 24109522 69.50 24109501 62.40 50-5657-63 24109523 74.55 24109502 68.85 57-6364-70 24109524 78.40 24109503 68.85 64-70







MALE FEMALE MALE

Lewis RatsSTRAIN CODE: 004

FEMALE



59.50 57.90

48.00 46.2547.50 47.50

225.15193.75150.90

69.50 62.4074.55 68.8578.40 68.85

Price Price36.45 35.2541.45 40.0546.40 45.3549.05 50.25

INBRED RATS


Material# Price Material# Price

Up to 28 24103918 121.25 24103892 118.95 Up to 28

29-35 24103919 129.90 24103893 127.35 29-35

36-42 24103920 136.65 24103894 134.00 36-42

43-49 24103921 145.00 24103895 142.25 43-49

50-56 24103922 151.45 24103896 148.50 50-56

57 plus 57 plus

Timed Pregnant 24103944 292.20 Timed Pregnant


Material# Obese Material# Obese

Up to 42 24104342 493.75 24104316 349.45 Up to 42

43-49 24104343 506.80 24104317 364.50 43-49

50-56 24104344 525.35 24104318 379.35 50-56

57-63 24104345 541.15 24104319 394.45 57-63

64-70 24104346 557.00 24104320 409.50 64-70

71 plus 71 plus


Material# Lean +/? Material# Lean +/?

Up to 42 24104397 214.10 24104371 172.60 Up to 42

43-49 24104398 229.85 24104372 187.55 43-49

50-56 24104399 245.70 24104373 202.40 50-56

57-63 24104400 261.60 24104374 217.35 57-63

64-70 24104401 277.35 24104375 232.35 64-70

71 plus 71 plus


409.50

Lean +/?

214.10

229.85

245.70

261.60

277.35

172.60

187.55

202.40

217.35

232.35

Lean +/?

SHHF RatsSTRAIN CODE: 374 (Lean +/?)

Age in Days*

MALE PRICE FEMALE PRICE

Age in Days*


557.00



2018 CUSTOMER PRICE2018 CHARLES RIVER LIST PRICE

Dahl/Salt Sensitive Rats (Dahl/SS)STRAIN CODE: 320


MALE

121.25

292.20

FEMALE

Price

118.95

127.35

134.00

142.25

148.50

Price

Prices upon Request

129.90

136.65

145.00

151.45

FEMALE MALE

Prices upon Request

SHHF RatsSTRAIN CODE: 373 (Obese)

MALE PRICE

Prices upon request

FEMALE PRICEMALE PRICE

Obese Obese

493.75

506.80

525.35

541.15

349.45

364.50

379.35

394.45

FEMALE PRICE

Prices upon request


DISEASE AND TRANSLATIONAL RATS



Up to 21 24100979 68.35 24100949 65.80 Up to 21

22-28 24100980 71.20 24100950 69.05 22-28

29-35 24100981 76.90 24100951 74.05 29-35

36-42 24100982 85.30 24100952 85.15 36-42

43-49 24100983 91.05 24100953 90.90 43-49

50-56 24100984 99.85 24100954 99.75 50-56

57-63 24100985 109.50 24100955 108.80 57-63

64-70 24100986 119.25 24100956 118.50 64-70

71-77 24100987 131.15 24100957 123.35 71-77

78-84 24100988 143.80 24100958 135.15 78-84

85-91 24100989 158.75 24100959 149.30 85-91

92-98 24100990 168.75 24100960 158.70 92-98

99-105 24100991 185.70 24100961 174.70 99-105

106 Plus 106 Plus

Retired breeders 24101032 100.35 24101031 96.60 Retired breeders

Littermates 21 days old only 24101028-21 105.80 24101028-21 105.80 Littermates 21 days old only

Lactating rat with litter 24101026 443.15 Lactating rat with litter

Timed pregnant 24101001 346.15 Timed pregnant




Up to 21 24101067 54.75 24101040 53.70 Up to 21

22-28 24101068 60.55 24101041 59.45 22-28

29-35 24101069 66.00 24101042 64.80 29-35

36-42 24101070 69.90 24101043 68.55 36-42

43-49 24101071 76.55 24101044 78.60 43-49

50-56 24101072 92.35 24101045 90.60 50-56

57-63 24101073 99.30 24101046 97.40 57-63

64-70 24101074 110.10 24101047 108.00 64-70

71-77 24101075 117.60 24101048 113.30 71-77

78-84 24101076 131.95 24101049 127.10 78-84

85-91 24101077 144.45 24101050 139.15 85-91

92-98 24101078 157.20 24101051 151.45 92-98

99-105 24101079 171.70 24101052 165.40 99-105

106 Plus 106 Plus



Lactating rat with litter 24101118 443.15 Lactating rat with litter




96.60

59.45

64.80

68.55

Age in Days* Price

54.75

60.55

66.00

FEMALE MALE

Age in Days*

MALE

Prices upon request



STRAIN CODE: 007

69.90

FEMALE

Price

53.70

WKY Rats (control for the SHR)STRAIN CODE: 008

143.80 135.15

158.75 149.30

443.15

68.35

71.20

76.90

85.30

78.60

90.60

97.40

151.45

165.40

108.00

76.55

92.35

110.10

117.60

131.95 127.10

139.15

113.30

346.15

324.50

144.45

157.20

171.70

98.50

103.80

Prices upon request

103.80

443.15

131.15

Prices upon request

99.30

SHR Rats

Age in Days*

MALE FEMALE

Age in Days*

123.35

91.05

99.85

109.50

119.25

65.80

69.05

74.05

MALE

Price

85.15

90.90

99.75

108.80

118.50

FEMALE

Price

346.15

324.50

168.75 158.70

185.70 174.70

Prices upon request

100.35 96.60

105.80 105.80




Up to 28 24104004 128.30 24103978 121.30 Up to 28

29-35 24104005 138.75 24103979 131.20 29-35

36-42 24104006 153.75 24103980 145.40 36-42

43-49 24104007 164.00 24103981 155.05 43-49

50-56 24104008 180.15 24103982 170.30 50-5657 plus 57 plus



Up to 42 24104176 414.10 24104150 295.50 Up to 42

43-49 24104177 427.85 24104151 309.40 43-49

50-56 24104178 441.90 24104152 323.50 50-56

57-63 24104179 455.95 24104153 337.45 57-63

64-70 24104180 469.75 24104154 351.30 64-7071 plus 71 plus


Material# Lean fa/+ Material# Lean fa/+

Up to 42 24104676 212.10 24104650 212.10 Up to 42

43-49 24104677 226.85 24104651 226.85 43-49

50-56 24104678 241.45 24104652 241.45 50-56

57-63 24104679 255.95 24104653 255.95 57-63

64-70 24104680 270.80 24104654 270.80 64-7071 plus 71 plus



Up to 42 24104232 168.40 24104206 168.40 Up to 42

43-49 24104233 183.15 24104207 183.15 43-49

50-56 24104234 197.75 24104208 197.75 50-56

57-63 24104235 212.10 24104209 212.10 57-63

64-70 24104236 226.85 24104210 226.85 64-7071 plus 71 plus


Prices upon request


Lean fa/+ Lean fa/+

212.10 212.10

226.85 226.85

241.45 241.45

255.95 255.95

270.80 270.80Prices upon request

ZDF RatsSTRAIN CODE: 371 (Lean +/?)



Prices upon request


Lean +/? Lean +/?

168.40 168.40

183.15 183.15

197.75 197.75

212.10 212.10

226.85 226.85

ZDF RatsSTRAIN CODE: 380 (Lean fa/+)




FEMALE PRICE

Prices upon request


ZDF RatsSTRAIN CODE: 370 (Obese)

128.30 121.30


138.75

469.75 351.30Prices upon request

FEMALE PRICE MALE PRICE

153.75 145.40

164.00 155.05

180.15 170.30

Obese Obese

414.10 295.50

427.85 309.40

441.90 323.50

455.95 337.45


FEMALE

Price

MALE PRICE

131.20

Stroke Prone Rats when ordering, specify SHRSPSTRAIN CODE: 324

Age in Days*

MALE FEMALE

Age in Days*

MALE

Price

Prices upon request




Up to 42 24104564 428.85 24104538 310.30 Up to 42

43-49 24104565 444.60 24104539 325.60 43-49

50-56 24104566 459.90 24104540 341.15 50-56

57-63 24104567 475.20 24104541 356.70 57-63

64-70 24104568 490.85 24104542 372.25 64-70

71 plus 71 plus



Up to 42 24104619 168.25 24104593 165.85 Up to 42

43-49 24104620 183.80 24104594 181.15 43-49

50-56 24104621 199.30 24104595 196.55 50-56

57-63 24104622 214.60 24104596 212.30 57-63

64-70 24104623 230.15 24104597 227.50 64-70

71 plus 71 plus



Up to 28 24102803 281.90 24102777 271.45 Up to 28

29-35 24102804 294.70 24102778 283.80 29-35

36-42 24102805 308.65 24102779 297.20 36-42

43-49 24102806 324.55 24102780 312.50 43-49

50-56 24102807 348.50 24102781 335.55 50-56

57-63 24102808 368.00 24102782 354.30 57-63

64-70 24102809 386.65 24102783 372.35 64-70

71-77 24102810 404.50 24102784 389.55 71-77

78-84 24102811 415.30 24102785 399.95 78-84

85-91 24102812 427.70 24102786 411.85 85-91


Material# Lean Material# Lean

Up to 28 24102860 71.85 24102834 69.20 Up to 28

29-35 24102861 74.75 24102835 71.95 29-35

36-42 24102862 77.75 24102836 74.90 36-42

43-49 24102863 88.00 24102837 84.70 43-49

50-56 24102864 96.85 24102838 93.25 50-56

57-63 24102865 105.85 24102839 101.90 57-63

64-70 24102866 110.40 24102840 106.30 64-70

71-77 24102867 114.85 24102841 110.55 71-77

78-84 24102868 119.70 24102842 115.20 78-84

85-91 24102869 126.65 24102843 122.00 85-91

Retired breeders 24102913 123.10 Retired breeders




FEMALE PRICEMALE PRICE


Age in Days*

STRAIN CODE: 378 (Obese)MALE PRICE

Age in Days*

MALE PRICE



FEMALE PRICE FEMALE PRICE

Zucker Rats STRAIN CODE: 185 (Obese)


168.25 165.85

183.80 181.15

199.30

ZSF1 Rats

ZSF1 Rats STRAIN CODE: 379 (Lean +/?)

Age in Days*


Age in Days*


Lean +/? Lean +/?

428.85 310.30

444.60 325.60

459.90 341.15

475.20 356.70

490.85 372.25

Lean +/? Lean +/?

196.55

214.60 212.30

230.15 227.50

Zucker Rats STRAIN CODE: 185 (Obese), 186 (Lean)

Age in Days*


Age in Days*


281.90 271.45

294.70 283.80

308.65 297.20

324.55 312.50

348.50 335.55

368.00

Obese Obese

Lean Lean

71.85 69.20

74.75 71.95

77.75 74.90

354.30

386.65 372.35

404.50 389.55

415.30 399.95

427.70 411.85

119.70 115.20

126.65 122.00

123.10

88.00 84.70

96.85 93.25

105.85 101.90

110.40 106.30

114.85 110.55




Up to 21 24106606 11.90 24106590 12.85 Up to 21

22-28 24106607 12.05 24106591 13.20 22-28

29-35 24106608 12.90 24106592 13.90 29-35

36-42 24106609 13.35 24106593 14.35 36-42

43-49 24106610 14.75 24106594 15.00 43-49

50-56 24106611 15.35 24106595 15.85 50-56

57 plus 57 plus

* Estimated age * Estimated age

Material# Price Material# PriceUp to 12 24101145 5.80 24101132 5.80 Up to 1213-15 24101146 6.35 24101133 6.35 13-1516-18 24101147 6.55 24101134 6.55 16-1819-21 24101148 6.70 24101135 6.70 19-2122-24 24101149 6.85 24101136 6.85 22-24


Littermates 21 days old only 24101190-21 7.80 24101190-21 7.80 Littermates 21 days old onlyLactating mouse with litter 24101187-1 75.80 Lactating mouse with litter


STRAIN CODE: 482 30% discount


Up to 21 24105886 21.40 24105846 20.75 Up to 21

22 - 28 24105887 23.60 24105847 23.25 22 - 28

29 - 35 24105888 23.95 24105848 23.45 29 - 35

36 - 42 24105889 24.15 24105849 23.60 36 - 42

43 - 49 24105890 24.30 24105850 23.95 43 - 49

50 Plus 50 Plus

** Isolator-maintained ** Isolator-maintained


CD-1® IGS MiceSTRAIN CODE: 022

CD1-Elite Mice**


Black Swiss MiceSTRAIN CODE: 492

14.53

16.28

16.42

12.05

12.90

13.35

14.75

15.35

Prices upon request

75.80

Prices upon request

Age in Days*


Prices upon request

FEMALE MALE

16.52

16.77

6.85

Weight in Grams Weight in Grams Price5.80 5.806.35 6.356.55 6.556.70 6.70

Price

41.3528.80

FEMALE


16.77

FEMALE

MALE

PRICE

14.98

MALE

16.91

17.01

FEMALE

PRICE

16.52

FEMALE MALE

14.35

15.00

15.85

MALE

PRICE

11.90

Age in Days*

FEMALE

PRICE

12.85

13.20

13.90

MALE


6.35 6.357.80 7.80

OUTBRED MICE




Littermates 21 days old only 24101259-21 10.05 24101259-21 10.05 Littermates 21 days old onlyLactating mouse with litter 24101257-1 90.30 Lactating mouse with litter



Up to 12 24101284 7.30 24101271 7.30 Up to 12

13-15 24101285 7.90 24101272 8.05 13-15

16-18 24101286 7.95 24101273 8.10 16-18

19-21 24101287 8.25 24101274 8.25 19-21

22-24 24101288 8.45 24101275 8.45 22-24

25 plus 25 plus



Lactating mouse with litter 24101326-1 88.95 Lactating mouse with litter



Material# Price Material# PriceUp to 21 24105722 42.35 24105696 42.35 Up to 2122-28 24105723 45.60 24105697 45.60 22-2829-35 24105724 49.50 24105698 49.50 29-3536-42 24105725 51.95 24105699 51.95 36-4243-49 24105726 53.15 24105700 53.15 43-4950-56 24105727 55.65 24105701 55.65 50-56


Littermates 21 days old only 24105747-21 151.50 24105747-21 151.50 Littermates 21 days old onlyLactating mouse with litter 24105746 404.80 Lactating mouse with litter



** Isolator-maintained ** Isolator-maintained

STRAIN CODE: 491

Age in Weeks* Material# Price Age in Weeks*4-6 24106297 13.80 4-6


13.80

Sentinel Mice (Isolator-Maintained)

FEMALE FEMALE

Price



CF-1™ MiceSTRAIN CODE: 023

CFW® Mice (Swiss Webster)STRAIN CODE: 024

SKH1-Elite Mice**STRAIN CODE: 477


Prices upon request

Weight in Grams Weight in Grams


FEMALE FEMALE MALE MALE

Prices upon request

Price Price7.50 7.508.20 8.20

7.9510.0590.3061.35

Prices upon request

FEMALE

MALE

MALEFEMALE MALE

FEMALE FEMALE MALE

40.45

8.258.30 8.308.35

Prices upon request

2018 CUSTOMER PRICE

290.55


51.9553.1555.65

54.15151.50151.50404.80

54.15

53.1555.65

45.60

8.35

8.2010.05

8.25

88.95

60.50

39.90

45.6049.5051.95

49.50

42.35PRICE42.35

PRICE

Price Price

7.30 7.30

7.90 8.05

7.95 8.10

8.25 8.25

8.45 8.45

8.05 7.90

9.90 9.90

OUTBRED MICE



Up to 28 24105646 33.45 24105606 35.85 Up to 28

29 - 35 24105647 37.65 24105607 40.45 29 - 35

36 - 42 24105648 40.45 24105608 42.70 36 - 42

43 - 49 24105649 42.70 24105609 45.50 43 - 49

50 - 56 24105650 47.80 24105610 50.65 50 - 56

57 plus 57 plus



Lactating mouse with litter 24105684 238.35 Lactating mouse with litter



**Isolator maintained **Isolator maintained


Up to 21 24108432 52.45 24108416 52.45 Up to 21

22-28 24108433 53.90 24108417 53.90 22-28

29-35 24108434 56.65 24108418 56.65 29-35

36-42 24108435 61.90 24108419 61.90 36-42

43-49 24108436 63.55 24108420 63.55 43-49

50-56 24108437 72.70 24108421 72.70 50-56

57 plus 57 plus






Up to 28 24106534 38.00 24106518 38.65 Up to 28

29 - 35 24106535 39.65 24106519 40.35 29 - 35

36 - 42 24106536 41.25 24106520 42.00 36 - 42

43 - 49 24106537 48.40 24106521 45.50 43 - 49

50 - 56 24106538 52.05 24106522 49.00 50 - 56

57 Plus 57 Plus


**Isolator-maintained **Isolator-maintained

38.00

39.65

41.25

48.40

42.00

52.05

45.50

49.00

PRICE

MALEFEMALE

Age in Days*

MALE

B6 Albino Mice**

Age in Days*

FEMALE

PRICE

53.90 53.90

56.65 56.65

72.70 72.70

Prices upon request

STRAIN CODE: 493

NCI A/JCr MiceSTRAIN CODE: 563

Age in Days*

MALE FEMALE

42.70

45.50

50.65



MALE

Age in Days*

42.70

47.80

Age in Days*

MALE FEMALE

PRICE

129-Elite Mice**STRAIN CODE: 476

FEMALE

33.45

37.65

40.45

PRICE

Prices upon request

Age in Days*

MALE

61.90

63.55 63.55

61.90

Prices upon request

86.85 86.00

286.45

229.10

28.15

40.60

Prices upon request

28.45

40.60

238.35

214.35

52.45

PRICE

52.45

FEMALE

PRICE

35.85

40.45

38.65

40.35


INBRED MICE



Up to 21 24108505 32.95 24108489 32.95 Up to 21

22-28 24108506 35.60 24108490 35.60 22-28

29-35 24108507 38.20 24108491 38.20 29-35

36-42 24108508 40.90 24108492 40.90 36-42

43-49 24108509 43.55 24108493 43.55 43-49

50-56 24108510 46.20 24108494 46.20 50-56

57 plus 57 plus





Littermates 21 days old only 24109084-21 29.75 24109084-21 29.75 Littermates 21 days old onlyLactating mouse with litter 24109081 239.70 Lactating mouse with litterTimed/Untimed pregnant 24109056 183.20 Timed/Untimed pregnant


STRAIN CODE: 547 30% discount (excludes retired breeders)


Up to 21 24107387 35.50 24107371 38.20 Up to 21

22-28 24107388 41.05 24107372 44.30 22-28

29-35 24107389 42.60 24107373 45.80 29-35

36-42 24107390 43.75 24107374 47.20 36-42

43-49 24107391 48.55 24107375 48.80 43-49

50-56 24107392 50.85 24107376 50.25 50-56

57-63 24107393 53.10 24107377 51.40 57-63

64 plus 64 plus




33.99 34.16

35.60 35.18

37.17 35.98

18.65

239.70183.20

29.75

BALB/c-Elite Mice**

Age in Days*

MALE FEMALE

Age in Days*

MALE

FEMALE FEMALE MALE MALE

Age in Days* Age in Days* PRICE PRICE


29.75

22.35 22.5023.10 23.2024.90 24.75


32.95

35.60

NCI B6-Ly5.1/Cr MiceSTRAIN CODE: 564

Age in Days*

MALE FEMALE

Age in Days*

MALE FEMALE

PRICE

43.55

46.20 46.20

Prices upon request

BALB/c MiceSTRAIN CODE: 028

25.35 25.3525.80 25.8026.35 26.3526.90 26.60

Prices upon request Prices upon request18.65

PRICE

29.82 32.06

30.63 33.04

FEMALE

PRICE PRICE

24.85 26.74

Prices upon request

28.74 31.01

20.05 21.50

32.95

35.60

38.20 38.20

31.00 31.00

40.90 40.90

43.55


35.00 35.00

INBRED MICE



Up to 21 24109124 26.30 24109098 27.95 Up to 21

22-28 24109125 30.90 24109099 31.90 22-28

29-35 24109126 32.20 24109100 33.05 29-35

36-42 24109127 35.15 24109101 35.15 36-42

43-49 24109128 39.65 24109102 37.80 43-49

50-56 24109129 40.40 24109103 38.45 50-56

57-63 24109130 42.70 24109104 41.45 57-63

64-70 24109131 50.30 24109105 42.20 64-70

71 plus 71 plus




Timed/Untimed pregnant 24109151 202.40 Timed/Untimed pregnant


STRAIN CODE: 027





STRAIN CODE: 475 30% discount (excludes special services)



Littermates 21 days old only 24105596-21 51.95 24105596-21 51.95 Littermates 21 days old onlyLactating mouse with litter 24105595 402.10 Lactating mouse with litter




FEMALE MALE FEMALE

29.60 29.6030.15 30.15

C57BL/6 Mice


22.55 24.25

28.00

25.15 26.1026.10 26.90

28.0029.10 28.70

24.33 26.78

MALE FEMALE

Age in Days*

MALE FEMALE

26.30 27.95

C3H MiceSTRAIN CODE: 025

Age in Days*


30.90 31.90

32.20 33.05

35.15

33.30 30.75

25.35 25.35

39.35 39.35

236.45

42.70 41.45

50.30 42.20

202.40

PRICE PRICE

28.18 30.9130.38 33.3232.20 33.9237.63 34.58

MALE FEMALE

Age in Days*

MALE FEMALE

PRICE PRICE

35.05 35.05


35.15

39.65 37.80

40.40 38.45

Prices upon request Prices upon request21.60 24.1032.75 32.75

281.55

C57BL/6-Elite Mice**

Age in Days*

240.10

PRICE PRICE

Age in Days* Age in Days*MALE

38.33 35.39

51.95 51.95402.10267.60

39.10 36.05Prices upon request Prices upon request

INBRED MICE







57 plus 57 plus

*Estimated age *Estimated age**Isolator-maintained **Isolator-maintained



Timed /Untimed pregnant 24103170 263.50 Timed /Untimed pregnant*Estimated age *Estimated age

Material# Price Material# PriceUp to 28 24105799 32.75 24105759 35.30 Up to 2829 - 35 24105800 35.00 24105760 37.10 29 - 3536 - 42 24105801 36.95 24105761 42.15 36 - 4243 - 49 24105802 39.15 24105762 42.70 43 - 4950 - 56 24105803 41.05 24105763 44.95 50 - 5657 Plus 57 Plus

Retired breeders 24105839 28.35 24105838 28.35 Retired breedersLittermates 21 days old only 24105837-21 37.40 24105837-21 37.40 Littermates 21 days old onlyLactating mouse with litter 24105836 264.35 Lactating mouse with litter


*Estimated age *Estimated age**Isolator-maintained **Isolator-maintained

MALE

PRICE73.00


FEMALE

PRICE73.00

Age in Days*

MALE FEMALE

PRICE PRICE

Fox Chase CB17™ Mice** STRAIN CODE: 251

2018 CUSTOMER PRICE


44.9049.80 45.7050.70 47.85

DBA/2 Mice

92.2097.75


FVB Mice

97.75

34.55 36.35

78.2586.40

39.15 37.0041.25 43.3044.50 44.1545.35

Age in Days*MALE FEMALE

Age in Days*

78.2586.4092.20

32.75 35.3035.00 37.1036.95 42.15

SJL-Elite Mice**STRAIN CODE: 478

Age in Days*

39.85 41.9547.25 49.2554.45 55.50

25.95 28.8028.90 31.6533.50

Prices upon request Prices upon request23.50 23.50

263.50

36.35

STRAIN CODE: 207


Age in Days*

MALE FEMALE

PRICE PRICE

227.70

MALE FEMALE

Age in Days*

MALE FEMALE

PRICE PRICE

28.35 28.3537.40 37.40

264.35

39.15 42.7041.05 44.95


216.35

30.65 30.6549.00 49.00

247.95

STRAIN CODE: 026


51.60 48.30Prices upon request Prices upon request

INBRED MICE



57 plus 57 plusLittermates 21 days old only 24109908-21 39.45 24109908-21 39.45 Littermates 21 days old only












STRAIN CODE: 033

STRAIN CODE: 176

STRAIN CODE: 099

MALE FEMALE MALE FEMALE


FEMALE

Age in Days*MALE


STRAIN CODE: 031

FEMALE

Age in Days*

MALE

B6C3F1 Mice

B6D2F1 Mice when ordering, specify BDF1

CB6F1 Mice


Age in Days*

MALE FEMALE

Age in Days*


Age in Days*

CD2F1 Mice when ordering, specify CDF1

33.80 36.8033.80 36.80

31.95 36.80

Age in Days*

MALE FEMALE

Age in Days*

FEMALE MALE


Price

31.20

48.90

Price23.60 26.4027.25 29.65

Price

30.50

Price25.10 27.1529.00 31.75

36.15

39.45 39.45

32.7037.40 36.1541.15 36.15

34.85

39.20 39.20

47.65

31.0536.60 32.5040.50 34.85

Prices upon request

39.25 39.25

Price Price25.45 27.85

Price Price25.90 28.2029.90 33.3030.75 34.15

38.60 36.3038.60 36.30

41.65 41.65

30.40 31.6533.75 32.7533.75 34.10

Prices upon request

HYBRID MICE


STRAIN CODE: 490 (Homozygous), 491 (Heterozygous)§ 251+ pricingHOMOZYGOUS MALE HOMOZYGOUS FEMALE

QUANTITY 1-100 QUANTITY 1-100Age in Days* Material# Price Material# Price Price Price

Up to 42 24106234A 79.90 24106216A 92.85 Up to 42 50.20 58.5043-56 24106236A 88.55 24106218A 103.00 43-56 58.90 69.9557-63 24106237A 100.65 24106219A 116.65 57-63 71.95 82.90

64 Plus 64 Plus*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.

STRAIN CODE: 490 (Homozygous), 491 (Heterozygous)§ 251+ pricingHOMOZYGOUS MALE HOMOZYGOUS FEMALEQUANTITY 101-250 QUANTITY 101-250

Age in Days* Material# Price Material# Price Price PriceUp to 42 24106234B 60.10 24106216B 69.85 Up to 42 50.20 58.5043-56 24106236B 69.05 24106218B 81.35 43-56 58.90 69.9557-63 24106237B 81.05 24106219B 93.80 57-63 71.95 82.90

64 Plus 64 Plus*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient §Heterozygous (haired) animals are not immunodeficient.

STRAIN CODE: 490 (Homozygous), 491 (Heterozygous)§ No discountHOMOZYGOUS MALE HOMOZYGOUS FEMALE

QUANTITY 251+ QUANTITY 251+Age in Days* Material# Price Material# Price Price Price

Up to 42 24106234C 50.20 24106216C 58.50 Up to 42 50.20 58.5043-56 24106236C 58.90 24106218C 69.95 43-56 58.90 69.9557-63 24106237C 71.95 24106219C 82.90 57-63 71.95 82.90

64 Plus 64 Plus*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient §Heterozygous (haired) animals are not immunodeficient.

MALE FEMALE Material# Price Material# Price PRICE PRICE

Up to 28 24103236 88.45 24103210 88.45 Up to 28 74.30 74.3029-35 24103237 94.50 24103211 94.50 29-35 79.38 79.3836-42 24103238 101.15 24103212 101.15 36-42 84.97 84.9743-49 24103239 106.50 24103213 106.50 43-49 89.46 89.4650-56 24103240 112.60 24103214 112.60 50-56 94.58 94.58

57 plus 57 plus*Estimated age *Estimated age**Congenic, isolator-maintained **Congenic, isolator-maintained

Prices upon request

Athymic Nude Mice**

Age in Days*QUANTITY 251+

Prices upon request

HOMOZYGOUS FEMALEQUANTITY 101-250 QUANTITY 101-250

Prices upon request

HOMOZYGOUS MALE HOMOZYGOUS FEMALE

Prices upon request

MALE FEMALE

Prices Upon Request

Fox Chase SCID® Mice** When Ordering, Specify C.B-17 SCIDSTRAIN CODE: 236


QUANTITY 1-100HOMOZYGOUS FEMALE

QUANTITY 1-100

Prices upon request

QUANTITY 251+

Prices upon request

Athymic Nude Mice**

Age in Days*

HOMOZYGOUS MALE

Prices upon request



Athymic Nude Mice**

Age in Days*

HOMOZYGOUS MALE

IMMUNODEFICIENT MODELS


STRAIN CODE: 250MALE FEMALE

Material# Price Material# Price PRICE PRICEUp to 28 24103369 92.85 24103343 93.75 Up to 28 77.99 78.7529-35 24103370 98.25 24103344 99.25 29-35 82.53 83.3736-42 24103371 104.65 24103345 104.65 36-42 87.91 87.9143-49 24103372 110.50 24103346 110.50 43-49 92.82 92.8250-56 24103373 116.00 24103347 116.00 50-56 97.44 97.44

57 plus 57 plus*Estimated age *Estimated age

**Congenic, isolator-maintained **Congenic, isolator-maintained

STRAIN CODE: 572 Pricing valid through June 30, 2018 No discount Pricing valid through June 30, 2018MALE FEMALE

Material# PROMO PRICE Material# Price PROMO PRICE PRICEUp to 21 24110016 60.00 24110000 93.50 Up to 35 60.00 93.5022-28 24110017 60.00 24110001 93.50 36-42 60.00 93.5029-35 24110018 60.00 24110002 93.50 43-49 60.00 93.5036-42 24110019 60.00 24110003 93.50 36-42 60.00 93.5043-49 24110020 60.00 24110004 93.50 43-49 60.00 93.5050-56 24110021 60.00 24110005 93.50 43-49 60.00 93.5057-63 24110022 63.00 24110006 98.00 43-49 63.00 98.0064-70 24110023 64.00 24110007 100.00 43-49 64.00 100.00

71-plus 71-plus

* Congenic, isolator-maintained * Congenic, isolator-maintained** Estimated age ** Estimated age


Up to 42 24104762 130.70 24104736 138.60 Up to 42 109.79 116.4243-56 24104764 141.35 24104738 152.95 43-56 118.73 128.48

56 Plus 56 Plus*Estimated age *Estimated age

**Congenic, isolator-maintained **Congenic, isolator-maintained


28-42 24102925 184.05 24102925 184.05 28-42 154.60 154.6043 plus 43 plus

**Inbred, isolator-maintained *Inbred, isolator-maintained

STRAIN CODE: 195 (Heterozygous)§ No discountMALE FEMALE

Material# Price Material# Price PRICE PRICE28-42 24102972 67.70 24102972 67.70 28-42 67.70 67.70

43 plus 43 plus

**Inbred, isolator-maintained *Inbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.


Age in Days*

Prices Upon Request*Estimated age *Estimated age

NU/NU BALB/c Mice**STRAIN CODE: 194 (Homozygous)

Prices upon request

Prices upon request

*Estimated age


Prices Upon Request

MALE FEMALE

Prices Upon Request

*Estimated age



NOD SCID Mice**STRAIN CODE: 394


Fox Chase SCID® Beige Mice**


NU/NU BALB/c Heterozygous Mice**

MALE FEMALE

Age in Days*

Prices upon request

Prices upon request

NCG Mice*

Age in Days** Age in Days*

Prices upon request

Prices Upon Request

MALE FEMALE

Prices Upon Request



STRAIN CODE: 086 (Homozygous), 087 (Heterozygous)§ 16% discount off 1-100 onlyHOMOZYGOUS MALE HOMOZYGOUS FEMALE


Up to 42 24102168A 79.90 24102151A 92.85 Up to 42 67.12 77.9943-56 24102170A 88.55 24102153A 103.00 43-56 74.38 86.5257-63 24102171A 99.70 24102154A 116.65 57-63 83.75 97.99


STRAIN CODE: 086 (Homozygous), 087 (Heterozygous)§ No discountHOMOZYGOUS MALE HOMOZYGOUS FEMALEQUANTITY 101-250 QUANTITY 101-250




QUANTITY 251+ QUANTITY 251+Age in Days* Material# Price Material# Price Price Price

Up to 42 24102168C 50.20 24102151C 58.45 Up to 42 50.20 58.4543-56 24102170C 58.90 24102153C 69.95 43-56 58.90 69.9557-63 24102171C 71.25 24102154C 82.90 57-63 71.25 82.90


STRAIN CODE: 201 (Homozygous) No discountMALE FEMALE


43 plus 43 plus

**Outbred, isolator-maintained **Outbred, isolator-maintained

STRAIN CODE: 202 (Heterozygous)§ No discountMALE FEMALE


43 plus 43 plus

**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.


NIH III Nude Mice**


Age in Days*

Prices Upon Request Prices upon request*Estimated age


Age in Days*QUANTITY 251+ QUANTITY 251+



Age in Days*

Prices Upon Request Prices upon request

*Estimated age

NIH III Heterozygous Mice**

Age in Days*QUANTITY 101-250 QUANTITY 101-250

QUANTITY 1-100

Prices upon request

NU/NU- CD-1® Mice**



HOMOZYGOUS MALE



Prices upon request


Age in Days*

HOMOZYGOUS MALE HOMOZYGOUS FEMALEQUANTITY 1-100

HOMOZYGOUS FEMALE



STRAIN CODE: 088 (Homozygous), 089 (Heterozygous)§ 16% discount off 1-100 onlyHOMOZYGOUS MALE HOMOZYGOUS FEMALE


Up to 42 24102260A 79.90 24102242A 92.85 Up to 42 67.12 77.9943-56 24102262A 88.55 24102244A 103.00 43-56 74.38 86.5257-63 24102263A 99.70 24102245A 115.45 57-63 83.75 96.98


STRAIN CODE: 088 (Homozygous), 089 (Heterozygous)§ No discountHOMOZYGOUS MALE HOMOZYGOUS FEMALEQUANTITY 101-250 QUANTITY 101-250




QUANTITY 251+ QUANTITY 251+Age in Days* Material# Price Material# Price Age in Days* Price Price

Up to 42 24102260C 50.20 24102242C 58.50 Up to 42 50.20 58.5043-56 24102262C 58.90 24102244C 69.95 43-56 58.90 69.9557-63 24102263C 71.25 24102245C 82.15 57-63 71.25 82.15


HOMOZYGOUS HOMOZYGOUSMALE FEMALE

Material# Price Material# Price PRICE PRICEUp to 4 24103861 160.65 24103835 163.65 Up to 4 134.95 137.47

5 24103862 201.10 24103836 201.10 5 168.92 168.926 24103863 241.60 24103837 241.60 6 202.94 202.947 24103864 278.90 24103838 278.90 7 234.28 234.288 24103865 319.70 24103839 319.70 8 268.55 268.559 24103866 356.50 24103840 356.50 9 299.46 299.4610 24103867 394.50 24103841 398.10 10 331.38 334.40

11 plus 11 plus


**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.

Prices upon request

NUDE RATS** When Ordering, Specify RNU


NU/NU Mice**



NU/NU Mice**


Age in Days*QUANTITY 101-250 QUANTITY 101-250

NU/NU Mice**

Age in Days*

HOMOZYGOUS MALE HOMOZYGOUS FEMALEQUANTITY 1-100 QUANTITY 1-100

QUANTITY 251+ QUANTITY 251+


STRAIN CODE: 316 (Homozygous), 118 (Heterozygous)§

Age in Weeks* Age in Weeks*MALE FEMALE

HOMOZYGOUS HOMOZYGOUS

Prices Upon Request






Up to 28 24106461 110.45 24106445 110.45 Up to 28 92.78 92.7829-35 24106462 117.85 24106446 117.85 29-35 98.99 98.9936-42 24106463 124.95 24106447 124.95 36-42 104.96 104.9643-49 24106464 131.60 24106448 131.60 43-49 110.54 110.5450-56 24106465 139.10 24106449 139.10 50-56 116.84 116.84

57 plus 57 plus*Estimated age *Estimated age**Congenic, isolator-maintained **Congenic, isolator-maintained

STRAIN CODE: 474 16% discount off 1-100 onlyMALE QUANTITY 1-100 FEMALE QUANTITY 1-100

Material# Price Material# Price Age in Days* Price PriceUp to 42 24105506A 96.05 24105486A 111.75 Up to 42 80.68 93.8743-56 24105508A 106.50 24105488A 123.90 43-56 89.46 104.0857-63 24105509A 121.05 24105489A 137.75 57-63 101.68 115.71

64 Plus 64 Plus*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained

STRAIN CODE: 474 No discountMALE QUANTITY 101-250 FEMALE QUANTITY 101-250

Material# Price Material# Price Age in Days* Price PriceUp to 42 24105506B 72.25 24105486B 84.05 Up to 42 72.25 84.0543-56 24105508B 82.95 24105488B 97.95 43-56 82.95 97.9557-63 24105509B 97.60 24105489B 110.85 57-63 97.60 110.85


STRAIN CODE: 474 No discountMALE QUANTITY 251+ FEMALE QUANTITY 251+

Material# Price Material# Price Age in Days* Price PriceUp to 42 24105506C 60.40 24105486C 70.25 Up to 42 60.40 70.2543-56 24105508C 70.85 24105488C 84.10 43-56 70.85 84.1057-63 24105509C 86.45 24105489C 98.00 57-63 86.45 98.00


STRAIN CODE: 561 No discountMALE FEMALE

Material# Price Material# Price PRICE PRICEUp to 21 24108281 102.55 24108265 102.55 Up to 21 102.55 102.5522-28 24108282 104.90 24108266 104.90 22-28 104.90 104.9029-35 24108283 107.20 24108267 107.20 29-35 107.20 107.2036-42 24108284 109.50 24108268 109.50 36-42 109.50 109.5043-49 24108285 111.80 24108269 111.80 43-49 111.80 111.8050-56 24108286 114.15 24108270 114.15 50-56 114.15 114.15

57 plus 57 plus

**Inbred, isolator-maintained **Inbred, isolator-maintained

Prices Upon Request

Prices upon request



SCID Hairless Outbred Mice* when ordering, specify SHO ®

SCID Hairless Congenic Mice** when ordering, specify SHC™ STRAIN CODE: 488


Prices upon request


Age in Days*


Age in Days*

Prices upon request

Age in Days*

Prices Upon Request


MALE FEMALE

MALE FEMALE

Prices upon request

MALE QUANTITY 251+ FEMALE QUANTITY 251+

Prices upon request

NCI SCID/NCr Mice**


Prices Upon Request

MALE QUANTITY 101-250 FEMALE QUANTITY 101-250

Prices upon request

MALE QUANTITY 1-100 FEMALE QUANTITY 1-100

Prices upon request




Up to 200 24101975 93.60 24101950 74.90 Up to 200201-250 24101976 102.55 24101951 82.05 201-250251-300 24101977 108.30 24101952 86.55 251-300301-350 24101978 116.35 24101953 93.15 301-350351-400 24101979 121.55 24101954 97.25 351-400401-450 24101980 127.00 24101955 101.70 401-450451-500 24101981 133.80 24101956 107.30 451-500501-550 24101982 144.45 24101957 115.65 501-550



Up to 200 24102574 228.60 24102555 228.60 Up to 200201-250 24102575 246.30 24102556 246.30 201-250251-300 24102576 275.30 24102557 275.30 251-300301-350 24102577 299.90 24102558 299.90 301-350351-400 24102578 324.25 24102559 324.25 351-400401-450 24102579 342.85 24102560 342.85 401-450451-500 24102580 355.00 24102561 355.00 451-500501-550 24102581 384.45 24102562 384.45 501-550

551 plus 651 plus


Up to 50 24101885 34.70 24101853 34.70 Up to 5051-60 24101886 38.35 24101854 38.35 51-6061-70 24101887 41.75 24101855 41.75 61-7071-80 24101888 47.10 24101856 47.10 71-8081-90 24101889 53.00 24101857 53.00 81-9091-100 24101890 59.30 24101858 59.30 91-100101-110 24101891 63.95 24101859 63.95 101-110111-120 24101892 66.60 24101860 66.60 111-120

121 plus 131 plusRetired breeders 24101943 54.00 24101942 54.00 Retired breedersTimed pregnant 24101918 123.90 Timed pregnant

Weight in Grams

FEMALE

MALE FEMALE

Weight in Grams

Specified Sex

Price

Specified Sex

LVG Golden Syrian Hamsters


Prices upon request

Weight in Grams

Weight in Grams

MALE FEMALE

MALE

93.60102.55108.30116.35

Price

2018 CUSTOMER PRICE2018 CHARLES RIVER LIST PRICE

Hartley Guinea PigsSTRAIN CODE: 051

IAF Hairless Guinea PigsSTRAIN CODE: 161

STRAIN CODE: 049

Weight in Grams

Prices upon request

Either Sex

Weight in Grams

324.25342.85355.00384.45

299.90324.25342.85355.00384.45

299.90


121.55

115.65

Either Sex

Price

74.9082.0586.5593.1597.25101.70107.30


127.00133.80144.45

MALE FEMALE

Price

275.30

228.60246.30275.30

228.60246.30

39.8041.30

123.90

53.00 53.0059.30 59.3063.95 63.9566.60 66.60

54.00 54.00

Price Price

34.70 34.7038.35 38.3541.75 41.7547.10 47.10

GUINEA PIGS & HAMSTERS


Material# Price Material# Price Up to 40 24103317 81.55 24103300 77.65 Up to 40

41-50 24103318 84.00 24103301 81.55 41-5051-60 24103319 90.40 24103302 84.00 51-6061-70 24103320 93.10 24103303 87.30 61-7071-80 24103321 96.30 24103304 93.10 71-8081-90 24103322 101.60 81-90

91 Plus 91 PlusRetired Breeder 24103335 81.55 24103334 81.55 Retired Breeder

Proven Breeder Pair 24103333 232.05 Proven Breeder PairUntimed Pregnant 24103329 243.65 Untimed Pregnant

Lactating mother with pups 24103330 255.55 Lactating mother with pups

Weight Weight

Kgs Lbs Material# Price Material# Price Kgs Lbs

1.4-1.8 3-4 24102061 139.25 24102040 139.25 1.4-1.8 3-41.9-2.3 4-5 24102063 157.90 24102042 157.90 1.9-2.3 4-52.4-2.7 5-6 24102065 175.60 24102044 175.60 2.4-2.7 5-62.8-3.0 6-7 24102066 201.05 24102045 201.05 2.8-3.0 6-7

3.1-3.3 7 24107101 271.05 24107099 271.05 3.1-3.3 7 3.4 - 3.6 8 24107102 292.80 24107100 292.80 3.4 - 3.6 8 3.7-3.9 8-9 24102070 325.65 24102049 325.65 3.7-3.9 8-9

Weight Weight

Kgs Lbs Material# Price Material# Price Kgs Lbs

1.4-1.8 3-4 24109405 139.25 24109385 139.25 1.4-1.8 3-41.9-2.3 4-5 24109407 157.90 24109387 157.90 1.9-2.3 4-52.4-2.7 5-6 24109409 175.60 24109389 175.60 2.4-2.7 5-62.8-3.0 6-7 24109410 201.05 24109390 201.05 2.8-3.0 6-7

3.1-3.3 7 24109411 271.05 24109391 271.05 3.1-3.3 7 3.4 - 3.6 8 24109412 292.80 24109392 292.80 3.4 - 3.6 8 3.7-3.9 8-9 24109413 325.65 24109393 325.65 3.7-3.9 8-9

MALE FEMALE

Mongolian Gerbils




MALE FEMALE STRAIN CODE: 243

201.05271.05292.80325.65

Specified Sex

Price

139.25157.90175.60201.05271.05292.80325.65

Either Sex

Price

139.25157.90175.60

STRAIN CODE: 052 (CR)New Zealand White Rabbits

Specified Sex Either Sex

243.65


255.55

Price Price81.55 77.6584.00 81.5590.40 84.0093.10 87.3096.30 93.10101.60

81.55 81.55232.05

New Zealand White RabbitsSTRAIN CODE: 571 (OAKWOOD)

Specified Sex Either Sex Specified Sex Either Sex

Price Price

139.25 139.25157.90 157.90175.60 175.60

325.65 325.65

201.05 201.05271.05 271.05292.80 292.80

GERBILS & RABBITS


LIST CUSTOMER LIST CUSTOMER LIST CUSTOMER

CODE RAT PRICE*† RAT PRICE*† MOUSE PRICE*† MOUSE PRICE*† G.PIG PRICE*† G.PIG PRICE*†

Carotid artery, common CARART 108.30 108.30 166.30 166.30 146.20 146.20

Carotid artery – cranial dosing2 CARART-CD 108.30 108.30 174.35 174.35 - -

Femoral artery FEMART 125.25 125.25 - - - -

Femoral vein FEMVEIN 106.80 106.80 - - - -

Jugular vein JUGVEIN 87.40 87.40 124.60 124.60 107.70 107.70

Double jugular vein3 JUGJUGVEIN 175.75 175.75 - - 214.85 214.85

Portal vein PORTVEIN 175.60 175.60 - - - -

Portal vein with T-tubing PVCTTUBING 213.10 213.10 - - - -

Vena cava (femoral vein) VENACAVA-FV 106.80 106.80 - - - -

1. Charles River partners with multiple catheter manufacturers to provide standard and customized catheters. Our standard vascular catheter is made of polyurethane with a

blunt-cut tip; however, round-tip catheters are available at an additional cost. Silicone, polyethylene, and blended catheters are available upon request. Specific catheters that are

able to accommodate automated samplers are also available at an additional cost.

2. For infusion only; no sample collection

3. Infusion using only one of these two catheters (indicated on shipping documentation)

* Surgical procedures do not include the price of the animal, shipping, or container charges.

† Add $12.65 Surcharge per animal for gas anesthesia. Add $15.45 surcharge per animal for immunodeficient and isolator-maintained models.



Bile duct‡ BILECANN 192.90 192.90 303.40 303.40 - -

Cecum1 CECUM 153.55 175.30 175.30 - -

Colon1 COLON 178.30 178.30 211.15 211.15 - -

Duodenum1 DUODCANN 159.25 159.25 246.50 246.50 - -

Ileum1 ILEUM 194.15 194.15 - - - -

Intraperitoneal catheterization1 IP-CATH 118.80 118.80 136.60 136.60 147.35 147.35

Intrathecal cannulation1 THECALCAN 212.25 212.25 - - - -

Jejunum1 JEJUNUM 196.05 196.05 208.00 208.00 - -

Stomach (gastric)1 STOMCANN 135.50 135.50 147.70 147.70 - -

Subcutaneous catheter1 SQCATH 60.90 60.90 95.10 95.10 81.20 81.20

Urinary bladder1 URIBLADCAN 128.00 128.00 149.10 149.10 - -




‡ The IACUC surgery protocol requires an extended postoperative holding period for animal recovery before shipping.


Vascular Catheterizations1

Non-Vascular Catheterizations

Any two vascular catheter procedures may be combined.

Any non-vascular catheter procedure may be combined with a vascular catheter procedure.

SURGICAL SERVICES




Adrenalectomy ADREX 25.15 25.15 26.45 26.45 - -

Adrenal demedullation ADREXDEMED 41.50 41.50 45.05 45.05 - -

Bile duct ligation BILEDUCLIG 69.85 69.85 87.45 87.45 - -

Castration CASTRATE 24.50 24.50 25.60 25.60 - -

Hypophysectomy (pharyngeal) – std weights‡ HYPOX 73.05 73.05 - - - -

Hypophysectomy < 75 g or > 200 g‡ HYPOX1 109.10 109.10 - - - -

Hysterectomy HYSTERX 76.55 76.55 81.90 81.90 - -

Nephrectomy – unilateral NEPHREX 42.75 42.75 45.70 45.70 - -

3/4 nephrectomy 34NEPHREX 138.85 138.85 152.60 152.60 - -

5/6 nephrectomy – multiple survival‡ 56NEPHREX 138.85 138.85 152.60 152.60 - -

Osteoarthritis model (MIA)‡ MIA14 32.15 32.15 - - - -

Ovariectomy OVARIEX 25.70 25.70 26.30 26.30 50.95 50.95

Parathyroidectomy‡ PARATHYROX 57.00 57.00 - - - -

Splenectomy SPLEENX 30.00 30.00 35.95 35.95 - -

Splenic denervation SPLENDNERV 143.30 143.30 - - -

Thymectomy THYMEX 54.35 54.35 68.60 68.60 - -

Thyroidectomy w/ parathyroid reimplant THYROX 54.95 54.95 - - - -

Thyroidectomy + parathyroidectomy THYRO+PARA 58.75 58.75 59.60 59.60 - -

Tubal ligation – bilateral BITUBALLIG 38.75 38.75 40.80 40.80 - -

Tubal ligation – unilateral UNTUBALLIG 32.40 32.40 33.40 33.40 - -

Ureter ligation URETERLIG 88.55 88.55 102.15 102.15 - -

Vagotomy (hepatic – standard procedure for mice)‡ VAGOX 78.85 78.85 80.95 80.95 - -

Vagotomy – stomach‡ VAGOX-STM 78.85 78.85 - - - -

Vagotomy (sub-diaphragmatic – standard procedure for rats)‡ VAGOX-SD 78.85 78.85 - - - -

Vasectomy VASEX 32.65 32.65 35.05 35.05 - -

Sham procedures are available upon request.



‡ The IACUC surgery protocol requeires an extended postoperative holding period for animal recovery before shipping.

Soft Tissue Procedures


A soft tissue procedure may be combined with a vascular catheter procedure.

SURGICAL SERVICES




Angiotensin II testing for IVC ANG II 101.00 101.00 - - - -

Bilateral brain cannulation1,2,‡ BIL-BRAIN 252.15 252.15 312.25 312.25 - -

Bilateral superior ganglion denervation GANGLIONBI 96.00 96.00 131.55 131.55 - -

Chronic constriction injury (CCI) of sciatic nerve BENNETT 190.45 190.45 - - - -

Intracisternal cannulation INTRCIST 194.95 194.95 - - - -

Intralateral ventricular cannulation1‡ IVC 140.40 140.40 162.30 162.30 - -

Intralateral ventricular cannulation – MRI compatible1‡ IVC-MRI 169.50 169.50 - - - -

Intralateral ventricular cannulation for pump connection1‡ IVCTUBING 163.75 163.75 196.05 196.05 - -

Intralateral ventricular cannulation for pump connection – MRI compatible1‡ IVCTUBINGMRI 196.00 196.00 - - - -

Intrathecal cannulation1‡ THECALCANN 212.25 212.25 - - - -

Microdialysis probe implantation2‡ UNI-BMICRO 186.25 186.25 - - - -

Olfactory bulbectomy OLFACTOREX 137.55 137.55 - - -

Parkinson’s model (chemical-60HDA)‡ PARKINSON 230.30 230.30 - - - -

Schizophrenia/epilepsy model MAM § § - - - -

Spinal nerve ligation (SNL) CHUNG 205.75 205.75 - - - -

Superior cervical ganglion denervation GANGLION 67.10 67.10 103.20 103.20 - -

Third Ventricular Cannulation1‡ 3RDVENTCAN 160.25 160.25 227.30 227.30 - -

Unilateral brain cannulation1,2,‡ UNI-BRAIN 152.55 152.55 172.95 172.95 - -


2. Customer provides coordinates.* Surgical procedures do not include the price of the animal, shipping or container charges.† Add $12.65 Surcharge per animal for gas anesthesia. Add $15.45 surcharge per animal for immunodeficient and isolator-maintained models.

‡ The IACUC surgery protocol requeires an extended postoperative holding period for animal recovery before shipping.§ Priced upon request.



Abdominal banding – hypertension model‡ ABDBAND 91.70 91.70 - - - -

Atherosclerosis – carotid artery embolectomy ATHERO-EMB 233.15 233.15 - - - -

Left coronary artery ligation‡ MYOINFARC 285.90 285.90 - - - -

Portal circulation redirected to the vena cava, bypassing the liver PORTCAVSHT 316.40 316.40 - - - -

Thoracic aortic banding‡ TABAND 156.20 156.20 - - - -

Thoracic Aortic Banding - Ascending Aorta‡ AATABAND 201.90 201.90 - - - -




Neurological Procedures


Cardiovascular Procedures

Any of these procedures may be combined with a vascular catheter procedure.

SURGICAL SERVICES




Blood Pressure Telemetry‡ TELEMBP 191.25 191.25 214.75 214.75 199.70 199.70

Blood Pressure + Electrocardiograph Telemetry‡ TELEMBPECG 234.00 234.00 279.55 279.55 236.25 236.25

Blood Pressure + Electroencephalograph Telemetry‡ TELEMBPEEG 234.00 234.00 - - - -

Electrocardiograph Telemetry‡ TELEMECG 160.80 160.80 166.75 166.75 166.30 166.30

Electroencephalograph + Electrocardiograph Telemetry‡ EEG/ECG 189.90 189.90 204.35 204.35 - -

Electroencephalograph + Electromyograph Telemetry‡ EEG/EMG 198.10 198.10 - - - -Electroencephalograph + Electroencephalograph + Electromyograph‡ EEG/EEG/EMG 338.90 338.90 - - - -

Electromyograph Telemetry‡ EMG 160.80 160.80 - - - -

Osmotic/Infusion Pump IMPLANT2 69.25 69.25 69.25 69.25 69.25 69.25

Pleural Pressure Telemetry‡ TELEMPP 270.85 270.85 - - - -

Pleural Pressure + Electrocardiograph Telemetry‡ TELEMPPECG 329.05 329.05 - - - -

Simple Injectable Implant IMPLANT 28.20 28.20 28.20 28.20 28.20 28.20

Temperature + Activity Telemetr‡ TELEMTA 137.80 137.80 - - - -

drop-shipped directly from the vendor to Charles River. Shipping address will be provided after order confirmation. Contact Charles River for other combinations of telemetry procedures.






Button application only (1 or 2 channel)1 BUTTON 34.00 34.00 34.00 34.00 - -

Button surgery (most buttons)1 BUTTONSURG 55.00 55.00 - - 55.00 55.00Instech brand one-channel magnetic button (VABR1B/22 for rats or guinea pigs and VABM1B/22 or VABM1B/25 for mice)2 BUTTON-1CH 84.75 84.75 84.75 84.75 84.75 84.75

Instech brand two-channel magnetic button (VABR2B/22 for rats or guinea pigs and VABM2B/22R22 or VAM2B/25R25 for mice)2 BUTTON-2CH 104.85 104.85 104.85 104.85 104.85 104.85

Instech brand three-channel magnetic button (VABR3B/22 for rats)2 BUTTON-3CH 116.45 116.45 - - - -

Instech brand one-channel non-magnetic button (VAB95BS)2 BUTONVAB95BS 84.75 84.75 - - 84.75 84.75

Instech brand one-channel magnetic mouse button (VAB62BS/22)2 BUTONVAB62BS - - 84.75 84.75 - -

Instech brand button cap (VABRC for rats or guinea pigs and VABM1C for mice)

BUTTON-CAP 23.45 23.45 23.45 23.45 23.45 23.45

Instech brand harness (application only)1 INSTJACKET 10.25 10.25 - - 10.25 10.25

Instech brand harness (single-channel VAH95AB)2 INSTJACKET+S 59.05 59.05 - - - -

Instech brand harness (two-channel VAHD115AB)2 INSTJACKET+D 81.45 81.45 - - - -

Instech brand harness for bile (VAHD115AB + VAHD115L)2 INSTJACKET+B 122.40 122.40 - - - -

Instech brand harness (three-channel VAHD115AB-1P)2 INSTJACKET+3CH 97.35 97.35 - - - -

SAI harness (application only)1 SAIJACKET 10.25 10.25 - - 10.25 10.25

SAI harness (single-channel QCH-23) SAIJACKET+S 46.50 46.50 - - - -

SAI harness (two-channel QCDH-23CW)2 SAIJACKET+D 64.25 64.25 - - - -

Instech PinPort™2 PINPORT 6.30 6.30 6.30 6.30 6.30 6.30

Instech PinPort™ supplied by customer1 PINPORT-CS 2.25 2.25 2.25 2.25 2.25 2.25

1. Items provided by customer. The items must be drop-shipped directly from the vendor to Charles River. Shipping address will be provided after order confirmation. 10% extra accessories are required to mitigate

short shipping due to unforeseen complications related to surgery.

2. Provided by Charles River. Limited stock kept in-house.


DEVICE IMPLANTS1

1. Charles River does not stock of any of these items, but will implant them when supplied by the customer in factory-direct packaging. Price does not include cost of these devices. The items must be


Optional Accessories for Catheterized Rodents

SURGICAL SERVICES


LIST CUSTOMER

CODE PRICE PRICE

Isoflurane anesthesia GAS 31.90 31.90

Antibiotic—ampicillin ANTIBIO-AMP 51.60 51.60

Antibiotic—enroflaxacin (Baytril) ANTIBIO-BAY 79.55 79.55

Price†

Rent-A-Surgeon 3,602.00

Rent-A-Trainer 5,542.00

* For more information on our Surgical Support Services, please visit www.criver.com.

† Pricing is per day per surgeon/trainer. Additional travel expenses will apply.

Surgical Support*

Miscellaneous Options


SURGICAL SERVICES


Description Code Price Description Code PriceNEW Trovan® brand identification chip - subcutaneous implant

TROVAN-ID 13.20NEW Trovan® brand identification chip - subcutaneous implant

TROVAN-ID 13.20

Avid brand identification chip – subcutaneous implant AVIDTRANS 13.60 Avid brand identification chip – subcutaneous implant AVIDTRANS 13.60Biomed brand identification chip – subcutaneous implant BIOMEDTRNS 13.60 Biomed brand identification chip – subcutaneous implant BIOMEDTRNS 13.60Ear punch EARPUNCH 4.30 Ear punch EARPUNCH 4.30Ear tags EARTAGS 4.30 Ear tags EARTAGS 4.30

RapID Tags® (customer supplied tag)† RAPID 5.60 RapID Tags® (customer supplied tag)† RAPID 5.60

Somark Labstamp® (mice only) LABSTAMP ID 5.90 Somark Labstamp® (mice only) LABSTAMP ID 5.90Tail Marking TAILMARK 4.05 Tail Marking TAILMARK 4.05Tattoo TATTOO 7.45 Tattoo TATTOO 7.45* Pre-ID™ services do not include the price of the animal, shipping, or container charges. * Pre-ID™ services do not include the price of the animal, shipping, or container charges.† Charles River can supply the tag and service for $11.80 per animal. † Charles River can supply the tag and service for $11.80 per animal.

Description Code Price Description Code PriceGlucose monitoring GLUCOSE 7.05 Glucose monitoring GLUCOSE 7.05* Pre-screening services do not include the price of the animal, shipping, or container * Pre-screening services do not include the price of the animal, shipping, or container charges. charges.

Description Code Price Description Code PriceInjection† INJECT 6.05 Injection† INJECT 6.05

IP (intraperitoneal) injection† INJ-IP 6.05 IP (intraperitoneal) injection† INJ-IP 6.05

IP (intraperitoneal) injection of pristane (mice only) PRISTANE 4.40 IP (intraperitoneal) injection of pristane (mice only) PRISTANE 4.40

Subcutaneous injection† INJ-SUB-Q 6.05 Subcutaneous injection† INJ-SUB-Q 6.05* Pre-Dosing/Pre-Injection services do not include the price of the animal, shipping, or * Pre-Dosing/Pre-Injection services do not include the price of the animal, shipping, orcontainer charges. container charges.† Customer-supplied injectable. † Customer-supplied injectable.

Pre-Screening Services*

Pre-Dosing/Pre-Injection Services*

2018 CUSTOMER PRICE



Pre-ID™ Services*

PRECONDITIONED MODELS

RESOURCES:

GENERAL TERMS & CONDITIONS OF SALE (“TERMS AND CONDITIONS”)


Charles River Laboratories, Inc. and its affi liates (“Charles River”) will provide the products (“Products”) and services (“Services”) described in the Charles River acknowledgment, quotation, protocol, or statement of work as applicable (“SOW”) and Charles River’s customer (“Customer”) will purchase the Products and Services pursuant to the specifi cations contained in the SOW and in accordance with these Terms and Conditions. These Terms and Conditions will also apply to all future purchases of Products and Services by Customer.

1. Binding CharacterAll sales and/or purchases of Products and Services are (a) governed by these Terms and Conditions and (b) made expressly conditioned upon Customer’s acceptance of these Terms and Conditions.

Customer’s acceptance of delivery of Products or Services will be deemed agreement to the Terms and Conditions.

No other document attempting to negate or otherwise modify the terms hereof, including any purchase order or request for proposal or any deviating or supplementing standard terms and conditions of Customer, will be binding upon Charles River unless expressly agreed to Charles River in writing. Instead these Terms and Conditions, including any special terms and conditions set forth separately as supplemented by any applicable provisions of Applicable Law, shall exclusively govern the sale of Products and Services by Charles River. This also applies if Charles River delivers Products or provides Services despite being aware of confl icting or additional standard terms and conditions of Customer.

2. Provision of the Products and Conduct of the Services Charles River will adhere to all laws, rules and regulations applicable to the provision of the Products and the conduct of the Services at the place of performance (“Applicable Law”).

If an amendment to the SOW requires additional or different work on the part of Charles River, Charles River may agree to conduct such work and will be paid an amount mutually agreed to by the parties. Deviations from the SOW may be made in an emergency without Customer’s approval, provided that Charles River uses commercially reasonable efforts to obtain Customer’s verbal approval, which will be subsequently confi rmed by Customer in writing. The parties acknowledge that during the course of performing the Services in accordance with the SOW, additional costs may be incurred by Charles River as a result of procedural changes, which do not amount to, or require a change in, the SOW, but which are deemed necessary by Charles River to successfully perform the Services, and which could not be foreseen at the time of the preparation of the SOW. If such procedural change occurs, Charles River will advise Customer prior to implementation and solicit Customer’s agreement as to the necessity and additional cost thereof. If Charles River is unable to contact Customer in advance, Customer agrees that in order to maintain the integrity of the Services, Charles River may proceed accordingly, and be entitled to recover such additional costs from Customer upon presentation of an explanation of such procedural changes and the necessity thereof.

3. Restrictions on Use and BreedingCustomer understands that Charles River engages in a comprehensive health monitoring, bioexclusion and quality control program. Customer agrees the results of this program only provide retrospective information relating to the timing and effectiveness of sampling and that Charles River’s program is not a substitute for customer’s own health monitoring and bioexclusion practices. Charles River does not warrant the Products will be free of infectious agents or other defects at time of delivery. Charles River will provide assistance for monitoring and testing to Customer upon written request subject to the availability of such assistance and Customer paying the standard fees for such assistance.

Products will be used by Customer in a safe manner and in accordance with all Applicable Laws. Customer agrees and will ensure that all animals purchased from Charles River, descendants of those animals derived by inbreeding or crossbreeding, including unmodifi ed derivatives of those animals or their descendants (“Models”) will not be: (i) used for any purpose other than the internal research of Customer in compliance with Applicable Law, (ii) bred (for sale or otherwise) or provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services, unless Charles River provides Customer with prior written authorization. For safety reasons, Customer will not, without the prior written consent of Charles River, return Products or shipping containers to Charles River.

The purchase of any Products conveys to Customer the non-transferable, non-sublicensable, non-exclusive right to internally use the Product and the components of the Products only in research conducted by Customer and specifi cally in accordance with the SOW. Customer cannot sell or otherwise transfer or make available to a third party the Products or their components or the Services for Commercial Purposes. “Commercial Purposes” means any activity for cash or other consideration including, but not limited to: (1) use of the Products or their components or materials made using the Products or their components in manufacturing, or to provide a service, information or data, or for clinical, therapeutic, diagnostic or prophylactic purposes or (2) resale of the Products or their components or materials made using the Product or its components, except by licensed distributors of Charles River, whether or not resold for use in research. The foregoing limitations are required by Charles River given the nature and sensitivity of the Products and Services provided by Charles River. To the extent that Charles River owns or controls (with the right to sublicense) patent rights or other intellectual property rights applicable to the Products or their intended use, those rights are licensed to Customer on a limited, revocable, non-exclusive, non-transferable and non-sublicensable basis only for the internal uses expressly permitted above and solely for the Products purchased. If Customer fails to comply with the foregoing limitations, in addition to any other remedies available to Charles River, the right of use granted under the preceding sentence will automatically terminate.

4. Compensation Unless otherwise agreed to by the parties, prices will be as per the price list (if applicable, price of Models is based on highest weight range) on the day of delivery, and they do not include applicable taxes, packaging, insurance or shipment expenses. The price list may be reviewed by Charles River annually. Customer will pay Charles River as set forth in the SOW. All invoices are due and payable thirty (30) days from the date of the invoice without any deductions and Customer agrees to pay all invoices submitted. Customer will not withhold payment, assert a right of retention or set off any counterclaims unless Customer’s counterclaims have been fi nally adjudicated by a competent court or have been acknowledged by Charles River in writing. All amounts not paid by Customer when due will accrue interest from the applicable due date until paid, at the highest rate permitted under Applicable Law. Charles River may also elect to cease or suspend the supply of the Products, any work on the Services or withhold required reports or other deliverables if Customer does not make payments when due and payable.

All applicable termination, delay or cancellation fees will be set forth in the current Research Models and Services catalog.

If in the judgment of Charles River, Customer’s fi nancial condition is precarious or there has been a materially adverse change in Customer’s fi nancial condition, Charles River will have the right to demand payment or other assurances which it deems adequate before providing any Products and Services.

5. Test ArticleCustomer will provide Charles River with suffi cient amounts of compounds, materials, animals, substances, devices and protocols meeting relevant specifi cations, including health and genetic data (“Test Articles”) with which to perform the Services. Customer will provide Charles River with complete and accurate data to apprise Charles River of the identity, strength, purity, stability, composition or other characteristics, proper storage and safe handling requirements of the Test Articles, including a Material Safety Data Sheet or equivalent documentation. Customer will certify to Charles River that the methods of synthesis, fabrication, or derivation of the Test Article have been documented. All costs associated with shipping the Test Articles to Charles River will be the responsibility of Customer, and Charles River will not be responsible for any loss, damage or destruction of the Test Articles while in transit. All Test Articles and Products used in connection with the Services will remain the property of Customer.

6. Reports Charles River will keep complete and accurate records of the status and progress of the Services if, and as required by, the SOW. Charles River will furnish a report or data containing information as specifi ed in the SOW. All reports will be prepared in the standard format of Charles River.

Neither Charles River nor Customer will publish any report or data prepared for Customer by Charles River without the prior written consent of the other party, which will not be unreasonably withheld.

If Charles River provides electronic access to the data, records, reports and other documentation and Customer elects to use such electronic access, the use of such electronic access will be governed by Charles River’s standard access terms and conditions which are available on request.

7. Inspections Upon reasonable advance written notice and during regular business hours, Charles River will permit Customer to visit the Charles River facilities where the Services are performed to monitor Charles River’s performance of the Services, in compliance with Charles River’s biosecurity measures, taking into account Charles River’s business requirements and ensuring an uninterrupted course of business at Charles River’s premises.

Charles River will notify Customer as soon as practical in the event of any regulatory inspection of Charles River’s facilities that directly impact the Services provided to Customer.

8. Ownership Any inventions, techniques and intellectual property, technology, commercial and industrial secrets, regardless of whether patented or registered, for providing the Products or performing the Services are, and will remain, Charles River’s exclusive property including, but not limited to, present and future documentation, scientifi c and technical data, test procedures and other information that is owned or licensed by Charles River and is not developed hereunder. Charles River will have the right to use concurrent control data as part of its general historical database. Any data, discoveries or inventions developed or generated, which directly relate to any information or materials provided by Customer hereunder including, without limitation, new data, uses, processes or compositions, will be the exclusive property of Customer. Charles River agrees to assist Customer in securing any patents, copyrights or other proprietary rights in such data, discoveries or inventions, and to perform all acts that may be reasonably required to vest in Customer all right, title and interest in such data, discoveries or inventions, and Charles River will be compensated at its standard rates for such assistance. All costs and expenses associated with establishing Customer’s rights therein will be Customer’s responsibility.

9. Archiving All reports and supporting documentation resulting from the Services are Customer’s property (“Materials”). Except as otherwise set forth in the SOW, and if requested in writing by Customer, Charles River will retain the Materials for a period of one year following the date of any fi nal report, or for such shorter period as may be required by Applicable Law. At the end of such period, Charles River will contact Customer to determine disposition of the Materials as follows: (a) extended storage of the Materials; (b) return of the Materials to Customer at Customer’s expense or (c) disposal of Materials at Customer’s expense. If Customer requests Charles River to continue to store the Materials and Charles River agrees, the cost for storage of the Materials will continue to be invoiced to Customer at Charles River’s then current rates. If Customer fails to give such instructions, Charles River will notify Customer, and if instructions are not forthcoming within thirty (30) days of said notifi cation, Charles River will have the option of continuing to store the Materials or returning the Materials to Customer at Customer’s expense. Customer will be liable for storage charges until the Materials are returned to Customer. While the Materials are in transit to Customer, all risk of loss or exposure to the Materials will be borne by Customer.

If the Materials require special storage requirements, additional charges for storage will be assessed and invoiced to Customer. Invoices will be issued annually in advance and are due and payable upon receipt.

RESOURCES:

GENERAL TERMS & CONDITIONS OF SALE (“TERMS AND CONDITIONS”)


10. Warranties

Customer warrants that it owns all rights, title and interest in the Test Articles furnished to Charles River and the intellectual property related thereto, and that Charles River’s use of the Test Articles does not infringe any third party rights.

Charles River warrants that the Products and Services will conform to the specifi cations contained in the SOW and Applicable Law. Charles River does not warrant or represent that the results of the Services will be acceptable to any regulatory or governmental agency to which they are presented nor that the results of the Services will enable Customer to further develop, market or otherwise exploit the Test Articles or any other product or service.

THE WARRANTY BY CHARLES RIVER SET FORTH HEREIN IS IN LIEU OF ANY AND ALL OTHER REPRESENTATIONS OR WARRANTIES, EXPRESS, IMPLIED OR STATUTORY INCLUDING, WITHOUT LIMITATION, ANY IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, SUITABILITY OF THE PRODUCTS AND SERVICES FOR CUSTOMER’S PURPOSES, IMPACT OF THE PRODUCTS AND SERVICES ON CUSTOMER’S OPERATIONS, OR NON-INFRINGEMENT OF A PATENT, TRADEMARK OR OTHER INTELLECTUAL PROPERTY RIGHT.

Any claim for breach of this warranty must be made in writing to Charles River within ten (10) business days after the Products are delivered or the completion of Services, after which time the Products or Services will be deemed fi nally accepted.

Risk of loss and title to the Products will pass to Customer once the Products leave Charles River’s facility or are delivered to a common carrier, as applicable.

11. Limitation of Liability

Charles River will not be liable for penalties or liquidated damages or for special, indirect, consequential punitive, exemplary or incidental damages of any type or kind (including, without limitation, lost profi ts) regardless of whether any such losses or damages are characterized as arising from breach of contract, breach of warranty, tort, negligence, strict liability or otherwise, even if Charles River is advised of the possibility of such losses or damages, or if such losses or damages are foreseeable.

Charles River’s liability, regardless of the form of action, will be limited to actual and foreseeable damages and will not exceed the total price paid for the Products or Services pursuant to which such liability arises. Charles River will not be liable for any damages arising from, or in connection with, any decision by Customer or any third party to further research, develop or market the Test Articles or any derivative or product or service related thereto, or the use made of the Products, Services or Test Articles derivative or service related thereto.

Subject to the limitations set forth in this Section, if Charles River commits a breach of the warranty set forth above, Charles River’s sole liability, and Customer’s sole remedy will be for Charles River to replace the Products or issue a credit therefore, or conform the work or portion of the Services affected by the breach to the relevant specifi cation.

12. Indemnities

Customer will defend, indemnify, save and hold harmless Charles River and its parent, subsidiaries and affi liates and their respective directors, offi cers, employees and agents from and against any claims, demands, suits, actions, causes of action, losses, damages, fi nes and liabilities, including reasonable professional fees (“Claim”) arising out of or in connection with or attributable to (a) the research, development, manufacture, distribution, use, sales or other disposition by Customer, or any distributor, collaborator, Customer, sublicense, representative or agent of Customer, of the Test Articles and/or any other substances upon which the Services were performed or any use made of the Products, or (b) any infringement of any third party’s patent or other intellectual property rights or unauthorized use or misappropriation of its know-how or trade secrets, or (c) Customer’s gross negligence or willful misconduct, or breach of this agreement or (d) personal injury related to contact with the Products during visits to Charles River’s facilities or after delivery of the Products to Customer, and will pay any costs and damages which, by fi nal judgement, after exhaustion of all reasonable appeals, may be assessed against them, provided that Customer is given written notice of the Claims within fi ve (5) days of the date of notice to Charles River and is given information, reasonable assistance and sole authority to defend and/or settle the Claim.

13. Insurance

Each party will have insurance suffi cient to cover its interest or potential liabilities hereunder including, but not limited to, worker’s compensation, if applicable, and comprehensive general liability.

14. Confi dentiality

In the course of providing the Products or performing the Services, Charles River and Customer may exchange proprietary and confi dential information. The parties will identify, in writing, such information as confi dential and/or proprietary. If a party intends to disclose confi dential information to the other party orally, the disclosing party will (i) alert the other party of the confi dential nature of the disclosure prior to the disclosure and (ii) provide written notice to the other party of the confi dential nature and contents of such disclosure within ten (10) days of the original disclosure. Each party will use its commercially reasonable efforts to maintain such information in confi dence and will employ reasonable and appropriate procedures to prevent its unauthorized publication or disclosure unless required by Applicable Law to disclose such information. Neither party will use the other party’s proprietary and/or confi dential information for any purpose other than in performance of this Agreement. The obligations of confi dentiality set forth in this Section will survive termination or expiration of this Agreement for a period of fi ve (5) years.

The confi dentiality provisions in this Section will not apply to any part of such information, which (i) is known to the receiving party at the time it was obtained from the disclosing party; (ii) is acquired by receiving party from a third party, and such third party did not obtain such information directly or indirectly from the disclosing party under obligation not to disclose; (iii) is or becomes published or otherwise in the public domain other than by violation of this Agreement by the receiving party; (iv) is independently developed by the receiving party without reference to or reliance upon the information provided by the disclosing party; or (v) is required to be disclosed by the receiving party to comply with applicable laws or governmental regulations; provided that the receiving party provides prompt written notice of such disclosure to the disclosing party and cooperates with the disclosing party’s reasonable and lawful actions to avoid and/or minimize the extent of such disclosure.

15. Termination

Unless otherwise specifi ed in the SOW, Customer will have the right to terminate the SOW at any time without cause upon thirty (30) days prior written notice to Charles River. In the event of such termination, Charles River will be paid for all Products provided or Services rendered through the effective date of termination, together with any additional expenses incurred in connection with the shutdown of the Services including, without limitation, any irrevocably committed costs and any cancellation or termination fee set forth in the SOW.

Either party may terminate these Terms and Conditions or SOW, as applicable, at any time upon thirty (30) days prior written notice to the other party, for material breach of the Terms and Conditions by the other party if such breach is not remedied to the non-breaching party’s reasonable satisfaction within the thirty (30) day notice period.

Upon termination, neither party will have any further obligations, except that (i) the liabilities accrued through the date of termination and (ii) the obligations which by their terms survive termination, including the applicable confi dentiality, record keeping, regulatory compliance, intellectual property and indemnifi cation provisions of these Terms and Conditions, will survive termination.

16. Force Majeure

Except with respect to the payment of any amount due hereunder, neither party will be considered in default of the performance of any obligation hereunder to the extent that the performance of such obligation is prevented or delayed by fi re, fl ood, earthquake, hurricane, explosion, disease, contamination, strike, acts of terrorism, war, insurrection, embargo, government requirement, civil or military authority, animal activism, act of God, or any other event, occurrence or condition which is not caused, in whole or in part, by that party, and which is beyond the reasonable control of that party.

17. Governing Law and Dispute Resolution

These Terms and Conditions and any dispute arising from or in connection with the sale of the Products and/or Services are governed by, and will be construed in accordance with, the laws of Delaware, excluding the United Nations Convention on the International Sale of Goods and without regard to any choice of law principle that would dictate the application of the law of another jurisdiction.

The parties will attempt to resolve through negotiations any controversy, claim, or dispute arising out of or in connection with these Terms and Conditions or its validity. If the negotiations are not successful, the controversy, claim, or dispute will be submitted to third-party mediation upon terms reasonably acceptable to the parties. If such claim, controversy or dispute is not resolved through mediation, upon written demand of either party, the claim, controversy or dispute will be submitted to arbitration. Such arbitration will take place in Boston, Massachusetts, will be conducted in English, and will proceed in accordance with the United Nations Commission on International Trade Law Arbitration Rules in force from time to time. A record and transcript of the proceedings will be maintained. Any award will be made in writing and in reasonable detail, setting forth the fi ndings of fact and conclusion of law supporting the award. The determination of a majority of the panel of arbitrators will be the decision of the arbitrators, which will be binding regardless of whether one of the parties fails or refuses to participate in the arbitration. The arbitrators will decide on the recovery of the costs of the arbitration, except expert and attorneys’ fees.

18. Miscellaneous

All notices from one party to the other will be in writing. Notices will be sent by internet transmission, overnight courier, or certifi ed mail, return receipt requested. All notices will be effective upon receipt.

The business relationship of Charles River to Customer is that of an independent contractor and not of a partnership, joint venture, employer, agent or any other kind of relationship.

These Terms and Conditions, and the rights and obligations hereunder, may not be assigned or transferred by either party without the prior written consent of the other party.

These Terms and Conditions, together with the SOW, set forth the entire agreement and understanding between the parties, superseding any and all previous statements, negotiations, documents, agreements and understandings, whether oral or written, as to the subject matter hereof.

In the event that any one or more of the provisions contained in these Terms and Conditions is held to be invalid, illegal or unenforceable in any respect, that invalidity, illegality or unenforceability will not affect any other term or condition, and all other terms and conditions will remain in full force and effect.

19. Intellectual Property

Charles River® and Charles River Laboratories® are registered trademarks of Charles River Laboratories, Inc. VAF/Plus®, VAF/Elite®, BlastoKit®, CD®, CD-1®, CFW®, EAD®, Gnoto-safe®, PRIA®, SHO®, THE POUND MOUSE®, Multiplexed Fluorometric ImmunoAssay® (MFIA®), Laboratory Testing Management® and MAX-BAX® are registered trademarks of Charles River Laboratories, Inc. CDF™, CF-1™, Sew Easy™, ICM™ and LTM™ are trademarks of Charles River Laboratories, Inc. The SourceSM is a service mark of Charles River Laboratories, Inc. Sprague Dawley® is a registered trademark of Harlan Sprague Dawley, Inc., Indianapolis, IN. SD™ is a Harlan Sprague Dawley trademark. Fox Chase SCID® is a registered trademark of the Fox Chase Cancer Center. Fox Chase CB17™ is a trademark of the Fox Chase Cancer Center. HydroGel™ is a trademark of ClearH2O®. Immortomouse® is a registered trademark of the Ludwig Institute for Cancer Research. PinPort™ is a trademark of Instech Laboratories, Inc., Plymouth Meeting, PA, USA. TARGATT™ is a trademark of Applied StemCell. Polymerase Chain Reaction (PCR) analysis is performed pursuant to licensing arrangements with Roche Molecular Systems, Inc. and The Perkin-Elmer Corporation. Microsatellite analysis is performed pursuant to licensing arrangements with the Marshfi eld Clinic. Purina #5008 is a trademark of Nestle Purina Petcare Company. Research Diets is a trademark of BioDAQ®. genOway® is a registered trademark of genOway S.A., Lyon, France. OpenArray® is a registered trademark of Biotrove, Inc. RODAC™ is a trademark of Becton, Dickinson and Company. TaqMan® is a registered trademark of Roche Molecular Systems, Inc. © Charles River Laboratories, Inc., 2018.

20. Language

The parties acknowledge that they have required that the Terms and Conditions, as well as all documents, notices and legal proceedings executed, given or instituted pursuant to or relating directly or indirectly hereto, be drawn up in English. Les parties reconnaissent avoir exigé la rédaction en anglais de la présente convention, ainsi que de tous documents exécutés, avis donnés et procédures judiciaires intentées, directement ou indirectement, à la suite ou relativement à la présente convention.

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