max gerson - a cancer therapy results of fifty cases part 1.doc

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Ensuring Quality CareThe Gerson Institute is a non-profit organization, established in 1977. s a publi! benefit, agen!ywe are dedicated to healing and preventing chrome and degenerative diseases based on the

vision, philosophy and successful work of Max Gerson. M.D. "e pursue this #ission by offering arange of progra#s and resour!es designed to pro$ide !urrent, a!!urate infor#ation to people%ho are interested in the Gerson Therapy&.

'a$ing fulfilled this role for () years %e ha$e be!o#e rightfully *no%n as the &starting pla!e&for all Gerson Therapy in+uiries, fro# both patients and #edi!al professionals ali*e. "e ta*e

pride in this role and %e are !o##itted to prote!ting the Gerson trade#ar* and the GersonTherapy ser$i!e #ar*, both of %hi!h be!a#e fully registered to the Gerson Institute in ((.

"hile o%nership of these #ar*s pro$ides us %ith !lear legal prote!tion, %e at the GersonInstitute $alue the# #ore as tools for ensuring +uality !are. "e are fully a%are of ho% dauntingany health !risis !an be and %e re!ognize our responsibility in pro$iding +ualified endorse#entsfor the prospe!ti$e Gerson Therapy patient. In adheren!e to our legal obligations %e %ill!ontinue to #a*e our resour!es in!reasingly useful to the publi! and %e %ill be proa!ti$e in

prote!ting the integrity and our o%nership of the Gerson na#e.

s you learn #ore about the Gerson Therapy %e en!ourage you to refer ba!* to the GersonInstitute for ad$i!e and ongoing support. 'ere are so#e of the progra#s offered by us that #ighthelp you on your %ayGerson Institute Approved Referral List

This is perhaps the #ost utilized progra# offered by the Gerson Institute. /ur referral list!onsists of #any fully trained pra!titioners, !lini!s, support groups, !o#panions and ho#e set-up!oordinators. If your Gerson Therapy hospital, physi!ian or support group does not ha$e our &sealof appro$al&, %e do not endorse the#0Edu!ation /utrea!h/ur Edu!ation /utrea!h 2rogra# !onsists of a $ariety of %or*shops and se#inars in!luding 0'e Gerson Therapy Training Program for icensed Professionals. 3aun!hed in 1994 this training

progra# in$ol$es a %ee* of instru!tion and an internship at a li!ensed Gerson !lini!. Graduatesare eligible to 5oin the Gerson Institute ppro$ed 6eferral 3ist and future !lini!s %ill only beli!ensed on!e *ey #edi!al staff ha$e !o#pleted this progra#. /ther %or*shops offered by theGerson Institute in!lude onsite Gerson Therapy !oo*ing !lasses, health #aintenan!e and &ho% to&se#inars and our in!reasingly popular Caregi$er Training "ee*end, the edu!ational pre-re+uisite for li!ensed Gerson !o#panions and ho#e set-up !oordinators.Gerson !ealing "ewsletter 4 issues a year8in!e 19:;, the Gerson !ealing "ewsletter has been the lin* bet%een the GersonInstitute and its patients and supporters. Ea!h issue in!ludes ne%s fro# the Institute,n updated e$ent !alendar, reports on alternati$e and idiopathi! trends, re!o$ered2atient testi#onials and arti!les %ritten by Gerson e<perts in!luding Charlotte

Gerson.

Speakers Bureau

Conta!t us to s!hedule a spea*er for your !o##unity organization, !hur!h or s!hool. e#inars!an be !atered to your needs and %e pla!e an e+ual e#phasis on disease pre$ention as %e doupon treat#ent.

Gerson Therapy /$ersight 2anellthough =a< Gerson de$eloped the Gerson Therapy o$er ) years ago, %e re!ognize that the%orld is e$er !hanging. This panel of re!ognized Gerson Therapy e<perts ensures that >rGerson&s proto!ol refle!ts rele$ant !hanges %ithout losing sight of his !ore prin!iples. This panel

dis!usses +uestions ranging fro# #ind-body #atters to dental pro!edures before sub#itting position state#ents to Gerson Institute #e#bers, patients and li!ensed !are pro$iders.

Patient Support Programs



The Gerson Institute offers a !o#prehensi$e range of patient support resour!es. These in!luderegular telephone support, a !o#prehensi$e %eb site, the Gerson Therapy ?ollo% @p 2rogra#,2atient upport Aet%or*, 2rodu!ts 6esour!es 3ist, 6e!o$ered 2atient 6eferral 3ist and an t'o#e Gerson Therapy 2a!*et for the #any people %ho are su!!essfully healing the#sel$esfro# ho#e.

2lease !onta!t our staff to find out #ore about any of these progra#s and resour!es. "e loo*for%ard to hearing fro# you.

A Cancer TherapyResults of Fifty Cases

and

The #ure of $dvanced #ancer by Diet Therapy

A Summary of 30 Years of Clinical Experimentation

Ma !erson" M#$#Gerson Institute



Copyright B 19):, 1999, (( by The Gerson Institute

il rights reser$ed. Ao part of this boo* #ay be reprodu!ed or utilized in any for# or by any#eans, ele!troni! or #e!hani!al, in!luding photo!opying, re!ording, or by any infor#ationstorage and retrie$al syste#, %ithout per#ission in %riting fro# the publisher.

/riginal !opyright. 19): by =a< Gerson, =.>.

The Gerson Institute1)7( e!ond $enuean >iego,C 9(11

Telephone 419-4:)-))9, or 1-:::-;-GE6/Ae#ail #ailDgerson.org %eb %%%.gerson.org

3ibrary of Congress Cataloging-in-2ubli!ation >ata

Gerson, =a< !an!er therapy results of fifty !ases a su##ary of years!lini!al e<peri#entation =a< Gerson.

p. C#./riginally published Ae% For* "hittier oo*s, H! 19):IA -::(4:-(-( pb* al*. paper8

I. Can!er->iet Therapy-Case tudies 1. TitleH>A3= 1. Aeoplas#s- therapy. Aot !+uired 6C(71.>)(G;7 1997 414.99&;4-

>C(1 >A3=>3C for 3ibrary of Congress94-)9)4 CI2

2rinted in the @nited tates of #eri!a

The na#es GersonJ1 and Gerson Therapy are %orld%ide trade#ar*s, ser$i!e #ar*s, andor registered

trade#ar*s or ser$i!e#ar*s of the Gerson Institute. ll 6ightsreser$ed. @sed by s5ennission.

The infor#ation !ontained in this boo* is for edu!ational and s!ientifi! purposes only.>o not unden.a*i any #edi!al uoainii#i or dietary !hanges %ithout the ad$i!e and supi5ori- of anappropriately li!ensed health!are pra!titioner.

2refa!e to the i<th Edition=a< Gerson, =.>. had the %isdo#, foresight, and !ourage to loo* beyond the pre$ailing#edi!al $ie%s of his day. /ut of years of !lini!al e<peri#entation, he arri$ed at so#e then-radi!al !on!epts

K >iet has a !onsiderable effe!t on al#ost all diseasesK The hu#an body !an heal itself gi$en the appropriate nutrientsK ny effe!ti$e treat#ent for degenerati$e disease #ust treat the %hole personK 2eople %ith serious illnesses #ust help their body deto<ify

"hile these ideas sound sensible today, they %ere al#ost blasphe#ous in the 19;s and 19)s.=ore than ; years ha$e passed sin!e =a< Gerson, =.>. died in =ar!h of 19)9. t that ti#e,

#ost !an!ers %ere not !onsidered !urable by orthodo< #edi!ine, and the #eri!an =edi!alsso!iation and #eri!an Can!er o!iety both flatly re5e!ted the notion that diet !ould ha$e any

effe!t on either the pre$ention or treat#ent of !an!er.In spite of the fier!e resistan!e to his ideas and #ethods, =a< Gerson %or*ed $irtually alone totreat and heal #any !an!ers !onsidered to be ter#inal, as %ell as nu#erous other diseases. 'e

mailto:[email protected]


http://www.gerson.org/

http://www.gerson.org/




%or*ed to publish and share infor#ation as best he !ould about the #ethods he had de$eloped. tthe ti#e of this printing in 1999, !an!er sur$i$al rates re#ain $irtually un!hanged, and thenu#ber of ne% !an!er diagnoses has !ontinued to in!rease ea!h year. Certain diseases !an!ersof li$er, lung, and pan!reas, a#ong others8 are still $irtual death senten!es. Ae% diagnoses of

pre$iously rare diseases are gro%ing at an alar#ing rate. The "ar on Can!er de!lared by then- president Ai<on in 1971 has, for #ost !an!ers, neither de!reased the nu#ber of ne% diagnoses,

nor i#pro$ed sur$i$al for those already diagnosed,?or o$er ( years, the Gerson Institute has %or*ed to help patients re!o$er fro# these

other%ise in!urable diseases, and to share *no%ledge of, and !ontinue resear!h andde$elop#ent of the safe, effe!ti$e Gerson Therapy approa!h to healing !an!er and otherdegenerati$e diseases. "hen %e started in 1977, al#ost no one %ould listen to %hat %e had tosay. "e %ere unable to treat patients in the @nited tates be!ause #edi!al boards threatened theli!enses of physi!ians %ho de$iated fro# !on$entional treat#ent #ethods. /nly the desperatelyill and dying, gi$en up by their do!tors, sought our help. In spite of the diffi!ulties, %esu!!eeded in helping hundreds of patients re!o$er fro# other%ise ter#inal diseases, tea!hingthousands #ore to ta*e steps to i#pro$e health and pre$ent the de$elop#ent of disease.

Today, fortunately, #u!h has !hanged. =any patients are no% de#anding and re!ei$ing8 fro#

their insuran!e !o#panies the option of pursuing holisti! treat#ent. gro%ing nu#ber of statesha$e established separate, independent li!ensing boards for pra!titioners using natural #ethods./ther states ha$e passed la%s re+uiring insuran!e !o#panies to pay for alternati$e !are, orspe!ifi!ally prote!ting pra!titioners using natural #ethods fro# reprisals by their #edi!al

boards. The Aational Institutes of 'ealth has established an /ffi!e of lternati$e =edi!ine,dedi!ated to resear!h and $alidation of holisti! #ethods of treat#ent. Independent #edi!alresear!hers ha$e do!u#ented and $erified the bio!he#i!al basis for #any i#portant ele#ents ofthe Gerson Therapy in #ore than arti!les in the peer-re$ie%ed #edi!al literature.

ll of these fa!tors ha$e led to a dra#ati! in!rease in interest in Gerson Therapy treat#ent.Today, our staff handles as #any as in+uiries a day fro# those see*ing infor#ation onGerson Therapy #edi!al edu!ation progra#s, referrals to pra!titioners, treat#ent !enters,half%ay houses, and therapy assistants. 2atients are see*ing Gerson treat#ent as a first !hoi!e,rather than a last hope. ?or those interested in #edi!al training, the Gerson Institute #aintains!ertifi!ation progra#s for physi!ians, treat#ent !enters, and ho#e !are assistants. "e area!ti$ely %or*ing to establish !ertified treat#ent !enters and #edi!al pra!titioners %orld%ide.Conta!t us for !urrent offerings.

"hile there are #any paths to %ellness, the Gerson Therapy is, in our opinion, the #ost!o#plete, all-en!o#passing approa!h for !o#prehensi$e healing. /ur !ontinuing resear!h isdesigned to ensure that %e #aintain and i#pro$e our ability to heal and pre$ent diseases,enhan!e %ell-being and longe$ity, and help indi$iduals operate at their pea* potential for a longand satisfying life into the (1st !entury and beyond.Charlotte Gerson Founder, Gerson Institute une !"""

DEDICATED TO MY WIFE MARGARET

!*no%ledg#ents

I ?EE3 IA>ETE> to e<press #y deep gratitude first to #y daughter, Gertrude elten, for her a!ti$e!ooperation as the #anager of the Can!er Clini! and her untiring help in the further de$elop#ent

of this ne% therapy.#ong the physi!ians, I %ish to e<press #y indebtedness to >r. Loseph Miegler,

6oentgenologist, for his loyal help in preparing $aluable N-ray pi!tures and ob5e!ti$e



e<planationsO >r. Purt 'einri!h for his e<a!t urologi!al and !ystos!opi! findingsO the late >r.La#es . 6i!!i for his pre!ise gyne!ologi!al reports and the late >r. Lonas ora* for hisenthusiasti! intelle!tual sti#ulusO and 2rofessor >r. "erner Pollath, Ger#any, for his ideal#anner of transfor#ing proble#s into realisti! biologi!al #aterial.

=y eldest daughter, Lohanna /berlander, helped energeti!ally in the translation andorganization of this %or*. =y youngest daughter, 3otte traus, helped %here$er she !ould %ith

great interest and understanding en!ourage#ent. =y se!retary, Erna 'arding, %or*ed diligently%ith enduring perse$eran!e in typing this #anus!ript.I %ish to a!*no%ledge %ith deep gratitude the !ooperation and en!ourage#ent re!ei$ed fro# the?oundation for Can!er Treat#ent, In!., a non-profit organization for#ed #any years ago bygrateful patients for the purpose of perpetuating the treat#ent as des!ribed in this boo*. To thefollo%ing dire!tors of the ?oundation, I %ould li*e to e<press #y spe!ial than*s 2rofessor >r.lbert !h%eitzer, 2rofessor 'enry !haefer-i##e#, =r, Carl Gropler, 6e$. >r. Er%in eale,2rofessor ?ul#er =ood, =r. 3ouis L. 6osenthal and =r. rnold L, /berlander.

CPA/"3E>G=EAT

"ithout the aid and en!ourage#ent of #y %ife, =argaret, I !ould not ha$e %ritten this boo*.To her, I ha$e dedi!ated this %or*.

=N GE6/A, =.>.

ContentsThis publi!ation is an e<e#plifi!ation of the %or* of =a< Gerson, =.>., on his treat#ent of

!an!er as dis!losed to the @nited tates enate in publi! hearings held Luly 1, ( and ,19;4. It isdesigned as a report on his !ontinued %or* in !an!er treat#ent, and %ill be filed %ith the @nitedtates enate %hen it again resu#es hearings on #eans of !uring and pre$enting !an!er. The title

page of the @. . enate Co##ittee report, !ontaining ((7 pages, follo%s#$"#%& &%'%$&#! 'E6IAG

before a ub!o##ittee of theC/=#iTTTEE /A ?/6EIGA 6E3TI/A @AITE> TTE EATE E$EATF-AIAT' C/AG6E

e!ond ession on . 1:7)

ill to authorize and re+uest the 2resident to underta*e to #obilize at so#e !on$enient pla!e in the@nited tates an ade+uate nu#ber of the "orld&s /utstanding E<perts, and !oordinate and utilize theirser$i!es in a upre#e Effort to >is!o$er =eans of Curing and 2re$enting Can!er.

Luly I, ( and , 19;4

2rinted for the use of the Co##ittee on ?oreign 6elations

:9;71 G/E6A=EAT 26IATIAG /??ICE

26T IC'2TE6 2GE

2refa!e

Introdu!tion (1 The e!ret of =y Treat#ent )( The Con!ept of TotalityR>e!isi$e in Can!er and other

>egenerati$e >iseases **

>ire!tions for General Autrition +*

; >e$elop#ent of the Co#bined >ietary 6egi#e in Can!er ur$ey8 (*

) The Theor ()



4 ?e% i#ilar Can!er Theories )7 2ara!elsus& >ietary 6egi#e -

: >ifferent uthors& Can!er Therapies by >iet ur$ey8 ))9 Early Can!er y#pto#s *

1 Can!er and 3i$er (11 ur$ey of Treat#ent of 3i$er 2athology by e$eral

uthors /**+ >e$elop#ent of 3i$er =edi!ation in Chroni! >egenera-

ti$e >iseases /-1 !ientists Ter# 6adiation a 2eril to ?uture of =an 0)

1; =ineral =etabolis# in >egenerati$e >iseases 0-

1) >istribution of Enzy#es in /rgans *1)

14 =ineral !!u#ulations in the Thyroid **(17 The 'ealing of Can!er **-1: 6ole of llergy in the 'ealing 2ro!ess of Can!er *()

19 Introdu!tion to the >iet *(-( Introdu!tion to Autrition and >iet *)

(1 The aitless >iet *)(/,+ alt in Can!er >iet *(

( Inse!ti!ides */

(; The ignifi!an!e of the Content of the oil to 'u#an>iseases /)

() Can!er >iet and its 2reparation *0/

(4 The 2ra!ti!e of the Therapy*-( ** 6ea!tionsR?lare @ps +1*

(: hort 2ra!ti!al E<planation of the =edi!ation +1)

(9 6ehabilitation of the Can!er 2atient +*(

=ost ?re+uent =ista*es of 2atients in the ppli!ationof the Treat#ent +*)

Che!* 3ist for Can!er 2atients on the Gerson Therapy +*/

1 =edi!ationRo#e ?ailures+*-

( Tables++( Total Treat#ent of a Typi!al Case +() 'ourly !hedule of Typi!al Treat#ent+(

Co#bined >ietary 6egi#e+(/ pe!ial Aotes to 2hysi!ian +0

>IGA/I 2GE

E<!eptionally large tu#or #ass of the pituitary gland.

urrounding bones partly destroyed. +)*!h%anno#a of the left !erebellar pontine angle.+))

Aeurofibro#ata %ith rapid gro%th, #any #etastases of sar!o#a type, also brain tu#or %ith he#iparesis, leftside.pongioblasto#a, left part thala#us, +

Cerebellar pontine angle tu#or. +/+

2ituitary tu#or. +//

Cer$i!al and upper thora!i! intra#edullary glio#a. +0(

Cer$i!al !ord angio#a. +0)

Chorionepithelio#a, #etastases in abdo#en and lungs. +0/

Cho!olate !yst of left o$ary, s!lrrhus !ar!ino#a of right breast %ith regional ly#ph node in$ol$e#ent. 'yper parathyroidis#, high blood pressure, angina pe!toris. +-1



6ight testi!le terrato#a. SE#bryonal Cell Car!ino#a.86egro%th in right groin. =etastases in periaorti!glands and both lungs. +-)

preading #elanosar!o#a. +--

!ti$e #elanosar!o#a. (1+

6e!urrent #elanosar!o#a spreading o$er the body. (1

!ti$e neurogeni! fibrosar!o#a %ith glands. (1

14 6etro-peritoneal ly#phosar!o#a. (1-

17 6e!urrent osteofibrosar!o#a Giant !ell tu#or of left

#astoid pro!ess8. '*1

1: 6etro-peritoneal ly#phosar!o#a a!ti$e, spreading toglands all around, also bilateral bron!heal. (*(

19 3y#phoblasto#a or 'odg*in&s >isease. (*

( 3y#phosar!o#a, spreading. (7(1 3y#phosar!o#a, regro%ing. (*-

(( 3y#phosar!o#a, subtotal o!!lusion. (+*

( =yosar!o#a, follo%ed by osteo#yelitis, subtro!hantheri! pathologi! fra!ture of left subtro!hantheri! area.()(; 2aget one >isease. () Tu#or #ass in aorti! %indo%. ((4 6egro%th of #alignant tu#or of right parotis. Chroni!

osteoarthritis. ((

(7 deno!ar!ino#a of both Thyroid and ig#oid. 7(: Car!ino#a of thyroid gland. ((0

(9 Car!ino#a of right breast, Grade III. ((-

deno!ar!ino#a of right breast %ith diffuse a<illaryly#ph node in$ol$e#ent and re!urren!e after radi!al

#aste!to#y. (1 naplasti! !ar!ino#a of the right breast %ith a<illary

#etastases and a regro%th in the !artilage of the fifthrib. (

( 6e!idi$es of breast !ar!ino#a. (/

2aget&s >isease, right breast. (0

; 6e!urrent basal !ell !ar!ino#a. (-

) asal !ell !ar!ino#a %ith undiagnosed !o#pli!ations. ()*

4 asal !ell !ar!ino#a of right upper lip. ()

7 6e!urrent basal !ell epithelio#a, sole, left foot. )): 6egro%th of left *idney sar!o#a. ()

9 2rostate !ar!ino#a %ith #etastases in lu#bar spine.rterios!lerosis and high blood pressure. ):

; Can!er of prostate, #etastases in left sa!roilia! 5oint. 4(;1 ron!hiogeni! !ar!ino#a, total right pneu#one!to#y.

Indi!ation of a!ti$e spreading !an!er. (

;( ron!hiogeni! !ar!ino#a, inoperable, suspi!ion of neoplas#a pressing on spinal !ord. 4

; 3eft sub#a<illary gland tu#or, #etastases in right upper lung lobe. 7(

;; 6egro%th of adeno!ar!ino#a of upper re!tu# %ith#etastases in lo%er abdo#en. (/

A/. >IGA/I

;) deno!ar!ino#a of sig#oid !olon. /bstru!tion ne!essi-



tating operation.

;4 Cer$i< !ar!ino#a %ith in$ol$e#ent of the $aginal $ault,#ore induration to the left $aginal $ault, +uite nodular. Induration also in the re!to-$aginal septu#.

;7 Cer$i< !ar!ino#a, inoperable !ase.;: +ua#ous !ell !ar!ino#a of left *idney, left ureter,

re!urren!e in urine bladder.;9 Can!er of the urine bladder. =igraine heada!he.) deno!ar!ino#a of uterus and #etastases to urine

bladder and $agina, %ith large urine fistula.

ppendi< I 'estonng the 'ealing =e!hanis# in other (-*

Chroni! >iseases by Charlotte Gerson traus

ppendi< II >e$elop#ent of the Gerson Can!er 1(

Therapy - a 3e!ture by >r. =a< Gerson

ppendi< III Conte#porary Con!erns in 6a% 3i$er +*

Lui!e Therapy =ar!h, 1998 A=E A> @T'/6 IA>EN +(



#AR$ !@LECT IA>EN

Introdu!tion

T'I //P has been %ritten to indi!ate that there is an effe!ti$e treat#ent of !an!er, e$en inad$an!ed !ases. ?or that reason it is ne!essary to a!+uaint the reader %ith obser$ations and datain the !an!er proble# %hi!h are used in the a!!epted !an!er treat#ents. The history of #edi!inehas sho%n that #any physi!ians adhere to their a!!usto#ed treat#ent %ith great tena!ity, andoften e$iden!e $ery strong allergi! rea!tions against e$erything that !ould possibly !hangetheir !usto#ary therapeuti! #ethods.

It is $ery %ell *no%n that great diffi!ulties e<ist, and that #any ob5e!tions #ay be raised

against publi!ation of a !an!er therapy %hi!h differs fro# the a!!epted #ethods. The ti#e isripe, ho%e$er, to %ipe out the deep pessi#is# %hi!h #ost physi!ians ha$e about e$erything thatassu#es to be therapeuti!ally effe!ti$e in degenerati$e diseases and espe!ially in !an!er.

t this ti#e, of !ourse, it is not possible to repla!e a !entury-long pessi#is# %ith ano$er%hel#ing opti#is#, "e all *no% that e$erything in biology is not as pre!ise as in#athe#ati!s or physi!s. I fear that it %ill not be possible, at least in the near future, to repair allthe da#age that #odern agri!ulture and !i$ilization ha$e brought to our li$es. I belie$e it isessential that people unite, in the old !onser$ati$e #anner, for the hu#anitarian purpose of

produ!ing nutrition for their fa#ilies and future generations as natural and unrefined as possible.The !o#ing years %ill #a*e it #ore and #ore i#perati$e that organi!ally gro%n fruit and$egetables %ill be, and #ust be, used for prote!tion against degenerati$e diseases, the pre$ention

of !an!er, and #ore so in the treat#ent of !an!er.

!!ording to present go$ern#ent statisti!s, one out of e$ery si< persons in our population %ill dieof !an!er. It %ill not be long before the entire population %ill ha$e to de!ide %hether %e %ill alldie of !an!er or %hether %e %ill ha$e enough %isdo#, !ourage, and %ill po%er to !hangefunda#entally all our li$ing and nutritional !onditions. ?or Can!er is a pheno#enon !oe<istent%ith the li$ing pro!ess . . .

"e %ill again need real house%i$es, not eager to sa$e *it!hen ti#e, but ho#e#a*ers %ho %illde$ote their li$es to the benefit of all, espe!ially the tas* of de$eloping and #aintaining a healthyfa#ily. abies %ould no longer be fed by a for#ula but %ould ha$e the natural #other&s #il*Othey %ould gro% up %ithout being affli!ted %ith a fatal disease su!h as leu*e#ia, and %ithout

being #entally retarded, both !onditions %hi!h are in!reasing rapidly at present.?or the future of !o#ing generations, I thin* it is high ti#e that %e !hange our agri!ulture andfood preser$ation #ethods. /ther%ise, %e %ill ha$e to in!rease our institutions for #ental

patients yearly, and %e %ill see the hospitals o$er!ro%ded %ith degenerati$e diseases e$en #orerapidly and in greater nu#bers than the hospitals the#sel$es !an be enlarged. e$enty years ago,leu*e#ia %as un*no%n in the @nited tates. ?ifty years ago, lung !an!er %as so seldo#obser$ed in !lini!s and autopsies that e$ery !ase %as %orthy of publi!ation. ut todayR%hat a!hange for the %orse. / 2uae mutatio rerum.3

The pra!ti!e of the treat#ent is a diffi!ult tas*. The treat#ent in the hospital as %ell as in theho#e re+uires so#ebody&s help all day long, parti!ularly in ad$an!ed !ases %here a life is atsta*e and the patient is $ery %ea*. The fa#ily has to gi$e up so#e of the so!ial life and do this

hu#anitarian %or* %ith deep de$otion. The de!line in our #ode# life is e$ident by this la!* ofde$otion for the si!* #e#bers of the fa#ily.

This is a short outline of the !ontents of this boo*.



?a!ts and proofs of fifty !an!er !ases ha$e been pla!ed in the foreground, %hile theories ande<planations ha$e been shortened.

1 Lesse Greenstein, 4iochemistry of #ancer, p. )9:, 19);.

C'2TE6 I

The e!ret of #y Treat#ent

/? C/@6E, there is none0 The heading is used be!ause I a# as*ed fre+uently, often reproa!hfully, by physi!ians about it.

The har#ony in the #etabolis# of all internal organs and syste#s #ust be #aintainedO itrefle!ts the eternal #ystery of life, e<pressed in our health and !ontinuan!e, Ea!h for# of life isa biologi! entity. Ea!h has only one purpose to gro% and reprodu!e %ith the aid of the food toits disposal.( The onset of #etaboli! disturban!e !onstitutes the beginning of disease.

&The Eternal 3ife has been de$eloped o$er #illions of years,&& Pollath said, and it %ill !ontinueto de$elop endlessly. Ea!h of its parts is i#portant. Aone is pri$ileged, for the internal e+uili-

briu# #ay not be disturbed.

?ollo%ing histori!al analysis, %e see in Pollath&s presentation that it %as #ainly s!ien!e andte!hnology %hi!h ha$e brought about the e$il, a part of it is o$ersi#plifi!ation.

y#pto#ati! treat#ent is har#ful %here$er in nature it is applied to the soil, plants, ani#alsor hu#an beings, or in #edi!ine.

Ea!h part is i#portant, but the %hole in its infinitely fine order is #ore i#portant.'istorysho%s that, fro# ti#e to ti#e, #en are s%ayed too easily by ne% thoughts and theories and byne% de$elop#ents in te!hnology and !he#istry, %hi!h they use as their bases in #edi!al

pra!ti!e.) This leads the# too far a%ay fro# nature,+ Quote of L. ?. "is!hhusen, Cle$eland, /hio.

ee Introdu!tion to >r. "erner Pollath&s boo* Die 5rdnung 6nserer "ahmng.'ippo*rates erlag, tuttgart, Ger#any,

;Ibid.4 The 6e$erend Luenger, 7ailure of Technology.

Therefore, it be!o#es ne!essary fro# ti#e to ti#e to bring#edi!al do!trine ba!* nearer to nature. See !hapter on 2ara!elsus. 8

ee*ing an e<planation for the negati$e attitude of the #a5ority of physi!ians to%ard the idea ofan effe!ti$e !an!er treat#ent, I ha$e !o#e to se$eral !on!lusions. ?irst, %e are all trained to

belie$e that !an!er is an in!urable disease. e!ondly, se$eral pre$ious atte#pts to introdu!e ane% !an!er treat#ent, in!luding theories and pro#ises, ha$e failed. The great falla!y lies in the#anner in %hi!h dietary tests are proposed and #ade, that is, by the use of one spe!ial substan!e

at a ti#e, obser$ing its effe!t on the body, follo%ed by another substan!e, and so forth. long ti#e ago, I %or*ed along the sa#e lines. The result %as a failure. Thereupon I started to

use al#ost the sa#e dietary regi#e de$eloped through years of e<perien!e, %hi!h I had pre-$iously applied in #y %or* in tuber!ulosis. 8Diattherapie der ungentuberkulose, 19;8 Toobser$e e<ternally the rea!tions of the diet and its !hanges I !hose s*in tuber!ulosis, so-!alledlupus vulgaris. 3ater I used the sa#e pro!edure in !an!er patients by obser$ing the rea!tions ofthe diet and its !hanges in in$ol$e#ents of the s*in. These obser$ations sho%ed the treat#entinade+uate for #alignan!ies of the intestinal tra!tO these need #ore intensi$e treat#ent. The#edi!ation for the tuber!ulosis treat#ent and that for !an!er treat#ent %ere de$eloped in asi#ilar #anner, but they are not the sa#e.

?ro# the beginning, the funda#ental idea %as and still is the follo%ing nor#al body has the

!apa!ity to *eep all !ells fun!tioning properly. It pre$ents any abnor#al transfor#ation andgro%th. Therefore, the natural tas* of a !an!er therapy is to bring the body ba!* to that nor#al

physiology, or as near to it as is possible. The ne<t tas* is to *eep the physiology of the



#etabolis# in that natural e+uilibriu#. nor#al body also has additional reser$es to suppress and destroy #alignan!ies. It does not

a!t in that #anner in !an!er patients, %here the !an!er gre% fro# the s#allest !ellular unitfreely, %ithout en!ountering any resistan!e. "hat for!es !an suppress su!h a de$elop#ent =yans%er is that this !an be a!!o#plished by the o<idizing enzy#es and the !onditions %hi!h#aintain their a!ti$ity. The best *no%n o<idizing enzy#es are arginase, !atalase, <antine

dehydrogenase, esterase, the urea o<idizing syste#s, !ystine-desulfurase, !yto!hro#e-!,!yto!hro#e o<idase and a#ino a!id o<idase and fla$in. ll these are lo%er in a!ti$ity in bothfetal li$er and hepato#a than in nor#al or regenerating li$er. /tto "arburg4 %as the first %hofound the #etaboli! de$iations of #alignant tissue fro# nor#al tissue and for#ulated

it by the !o-effi!ient anaerobi! gly!olysis!ell respiration8

In nor#al tissue it is zero.In e#bryoni! tissue .1In benign tu#ors .;) to 1.;)In #alignant tissue up to 1(.

/n the !ontrary, al*aline phosphatases and the dea#inases are higher in a!ti$ity in fetal li$er andhepato#a than in nor#al and regenerating li$er. The $ery fre+uently e<pressed $ie% is that fetaland neoplasti! hepati! tissue sho% a si#ilar o<idizing pattern to e#bryoni!, #ore pri#iti$e, andless differentiated tissue.

It is *no%n that in pri#iti$e for#s of life the energy of the !ells is deri$ed al#ost entirely fro#anaerobi! !onditions or through fer#entation. In higher ani#als, the lo%er fer#entati$eanaerobi! syste#s are #i<ed %ith o<idation syste#s, %hereby #ore and #ore #ole!ular o<ygenis utilized, transported fro# the respiration of the lungs. The #alignan!ies in hu#an beings!ontinuously fall ba!* deeper and deeper into fer#entation. The #a5or general part of the body

be!o#es #ore poisoned and #ore redu!ed in its defense and healing po%er.

The ideal tas* of !an!er therapy is to restore the fun!tion of the o<idizing syste#s in the entireorganis#. This, of !ourse, is diffi!ult to a!!o#plish. It in$ol$es the follo%ing 18 deto<i!ation ofthe %hole body, (8 pro$iding the essential #ineral !ontents of the potassiu# group, 8 addingo<idizing enzy#es !ontinuously as long as they are not rea!ti$ated and built in the body in thefor# of green leaf 5ui!e and fresh !alf&s li$er 5ui!eJ8. This %ill !reate a near nor#al !ondition ofthe o<idizing syste# in the body, to %hi!h #alignant !ells %ith the fer#entation syste# !annotadapt. Autrition is generally an e<ogenous fa!tor, but the inta*e of food, slightly to<i!, belo% the

le$el of a sti#ulant, brings about

: /tto "arburg, The Metabolism of Tumors, Constable Co. 3td 3ondon, 19. J ee ppendi< III.page ;(1

a disposition in the organis#, %hi!h #ay be regarded as pre#orbid. >iet, ho%e$er, appeared toha$e no influen!e on li$er tu#ors in rats produ!ed by (-a!etylaniino-fluorene. The #anner in%hi!h diet produ!es pro!ar!inogeni! or anti!ar!inogeni! effe!t is un*no%n. Che#i!al differen!es

bet%een #ito!hondria of nor#al li$er and #ouse li$er hepato#a ha$e been reported by'ogeboo# and !hneider.

o#e interesting obser$ations in regard to the influen!e of diet on the de$elop#ent ofspontaneous hepato#as in inbred C' #i!e %ere #ade by Tannenbau# and il$erstone. Thesein$estigators ha$e sho%n that in!rease of fat in the diet fro# t%o per !ent to ( per !entin!reased the rate of hepato#a for#ation fro# 7 per !ent to ) per !ent. 3o% ribofla$in inta*e

resulted in a de!rease of hepato#a for#ation. This !an be attributed to the redu!ed !alori! inta*e,%hi!h has been sho%n to inhibit gro%th of hepato#as in this spe!ies. It has li*e%ise been sho%nthat, !ontrary to the e<perien!es %ith indu!ed hepato#as in rats, the spontaneous tu#ors in #i!e



are not a!!elerated by a ri!e diet but on the !ontrary are a!!elerated by in!reased !asein !ontent.=ethionine has li*e%ise been sho%n to a!!elerate the de$elop#ent of these tu#ors in #i!e. The!on!lusion is dra%n that the sulphur-!ontaining a#ino a!ids, %hi!h are ne!essary for nor#algro%th, are also ne!essary for gro%th and de$elop#ent of these neoplas#s. gain a startlingindi!ation of the si#ilarity bet%een physiologi! gro%th and neoplasial7

/ur #odern !i$ilization brings about a pre#orbid disposition in al#ost all hu#an beings,

differing only in degree. It #ay be regarded in so#e of us8 as a pre-neoplasti! !ondition!!ording to go$ern#ent statisti!s, this applies to one out of si<. The per!entage has a!!eleratedin the last () yearsO !ar!ino#as and undefined !an!ers in #an*ind are in!reasing yearly.

efore I %as ready to de#onstrate #y tuber!ulosis results in the =edi!al o!iety of erlin, '.Monde* as*ed #e to dis!uss the diet and its effe!ts %ith the best *no%n nutritional biologist,2rofessor E. bderhalden, @ni$ersity 'alle a . . . fter a short dis!ussion his ad$i!e %as It isi#possible to e<plore one or another substan!e alone. "e need, as you did, a si#ple nutritionalground%or*. /n this basis you !an %or* out the therapy by

% Mitchell A# Spell&erg" Disease of the Liver, !rune and Stratton" '()*" p# '+,#

adding or subtra!ting one or another substan!e and obser$e the effe!t 'a$ing su!h results I%ould not !hange anything. The sa#e thing is true for #edi!ation. =ost of it %e !annot e<plain,the result is de!isi$e.

Autrition is pri#arily an e<ogenous fa!tor, but a !onstantly !hanged unnatural nutrition bringsabout in our organis# that internal pre#orbid disposition.: I #ay add It is a slo%ly progressi$einternal adaptation %hi!h the body perfor#s, as each daily poisonous irritation le$el is #ost

probably too lo% to !ause a defensi$e rea!tion until a tu#or !an gro% %hile the body isundefended and poisons !ontinue to a!!u#ulate.9

fter #y se!ond le!ture at the International Can!er Congress in Ger#any in /!tober, 19)(,2rofessor "erner Pollath handed #e his latest boo* Die 5rdnung 6nserer "ahrung The /rder

of /ur Autrition 19)(U %ith the ins!ription "ith gratitude for your >o!trine IAC@63E IC@63E.

The se!ret of #y treat#ent is that the nutritional proble# is not %ell enough understood in$ie% of the *no%ledge and infor#ation on hand at present. bderhalden&s and other s!ientists&ad$i!e helped a great deal to sol$e the proble# in !lini!al pra!ti!e. I thin* the #edi!ation is alittle #ore sub5e!t to #edi!al argu#entation. oth #ay be t%o other unsol$ed proble#s in#edi!ineO our tas* is to a!*no%ledge this and to present the fa$orable results of the treat#ent.

In a nor#al body all is ali$e, espe!ially the basi! substan!es built by the #inerals, they ha$eionized or a!ti$ated potassiu# and #inerals of the potassiu# group %ith positi$e ele!tri!al poten-tials.

In a si!* bodyR#ainly in !an!erRpotassiu# is inactive9sodium and #inerals of the sodiu#

group are ionized %ith negati$e potentials. /n this basis all other abnor#al pro!esses de$elop as!onse+uen!es. ?or healing purposes the body #ust be deto<ifiedRa!ti$ated %ith ionized#inerals, natural food so that the essential organs !an fun!tion again.

?or healing the body brings about a *ind of infla##ation. That is a tre#endous transfor#ati$erea!tion. This renders the body hypersensiti$e or allergi! to a high degree against abnor#al

: Professor ieg#und, p. (77. Gan:heits behandlung der Geschwulsterkrankun9 gen, '()+#

-ippokrates .erlag#

( See Leonnard /ickenden%s OUT Daily Poison, $evin0Adafr Co#" '())#

or strange substan!es in!luding ba!illi, !an!er !ells, s!ars, et!.8, Conse+uently the #ore

#alignant the !ells are the #ore effe!ti$e is the treat#ent. I thin* this is the end effe!t or se!retof the treat#ent. The s!hool of $on erg#ar# did re$eal so#e of the features of the allergi!rea!tion.1

#e!hani!al #ethod and se$eral types of sti#ulation !ould not a!!o#plish su!h a purpose.



The atte#pts of ugust ier, '. 3a#pert, Ger#any and /. ela%ry, uffalo 1( and others didnot su!!eed in helping degenerati$e diseases or !an!er.

1 ee !hapter se$enteen.11 !yperaemie ah !ellmittel.1( Tumorbeeinfiussung dvrch !yperthermic und !uveraemle. Parl ? 'aue

erlag, @l# a. >or.au, 19)7.

C'2TE6 II

The Con!ept of Totality->e!isi$e in Can!er and /ther>egenerati$e >iseases

CACE6 I a !hroni!, degenerati$e disease, %here al#ost all essential organs are in$ol$ed in the#ore ad$an!ed !ases The entire #etabolis# %ith the intestinal tra!t and its adne<a, the li$er and

pan!reas, the !ir!ulatory apparatus the !ellular e<!hange supporter 8, the *idneys and bile syste#as #ain eli#ination organs8, the reti!ulo-endothelial and ly#phati! syste# as defense ap-

paratus8, the !entral ner$ous syste# and espe!ially the $is!eral ner$ous syste# for #ost#etaboli! and #otori! purposes.

>r. Ai!hols %as probably one of the first in our ti#e %ho re!ognized the !on!ept of totalityas applied to disease. 'e !o#bined the follo%ing !lini!al appearan!es E#otional, nutritional,

poisons, infe!tions, a!!idents and inheritan!e as underlying !auses for diseases Ao %onder %eare all si!* . . . and s!ien!e is no longer s!ien!e %hen it atte#pts to $iolate God&s natural la%. 1

'e did not #ention degenerati$e diseases in general, and did not approa!h the !an!er proble# inhis arti!le. 'o%e$er, his idea sho%s in #any respe!ts progress in the !on!ept of a!ute and!hroni! diseases.

o#e !an!er biologists are of the opinion that !an!er is a pheno#enon !o-e<istent %ith theli$ing pro!esses, that the !an!er !ell is not so#ething li$ing e<!lusi$ely fro# the body, andthat the !an!er !ell is not a spe!ial syste# isolated fro# the li$ing organis#. They are united

with and part of the whole1: ee The Texas 4ankers &ecord for =ay, 19)(, 3ee

?dt, Ao. ):. 11

the natural pro!essesO it is also the rule in art, in philosophy, in #usi!, in physi!s, %here the#ost learned s!holars found the !on!ept of totality ali$e in their fields of resear!h and %or*. sa fe% sa#ples, I %ould li*e to #ention first 'enry >ru#ond&s philosophi!al %or* "atural aw

in the 'piritual ;orld 1::8. The basis of it is e<pressed in his %ords The !ontinuity of the physi!al %orld to the spiritual. This #eans the !oheren!e of the physi!al inorgani! po%ers as

they are transferred basi!ally into the organi! %orld of plants and ani#als. In #an, there are theele!tri!al potentials outstanding in the life of the !ells. They are espe!ially a!!u#ulated in thener$ous syste#, %hi!h is ulti#ately our spiritual organ !apable of !reating progress and greata!!o#plish#ents.

/ur Daily Potion by 3eonard "i!*enden, >e$ia-dair Co., Ae% For*, 19)).

In physi!s, lbert Einstein&s first great %or* %as &elativity of 'pace and Time. t first thetheory %as !onsidered fantasti!. 3ater it %as generally a!!epted. Einstein&s ad$an!ed studies dealt%ith a transfor#ation of light and the photoele!tri! effe!t. ?inally, his transfor#ation theory

atte#pted to in!lude gra$ity, #agnetis#, and ele!tri!ity into one basi! physi!al syste#, %hi!h he!alled the @nified ?ield ie%R most difficult to prove.

In art, as an e<a#ple of this !on!ept, is the %or* of !haefer-i##ern, %ho too* the

http://dor.au/

http://dor.au/



e<planation of art out of the narro% li#itations of the old rational prin!iples and de#onstrated

that art is a !reati$e po%er, inherent in our brain fun!tions, de$eloping a!!ording to the body&s gro%th, #ental, e#otional and intelle!tual #aturity. !haefer-i##e# said that The

!reati$e potentialities in #en and in %o#en, in business and the professions, are al%ays presentas an entity, united %ith all other po%ers of the body. !haefer-i##e# used art to unfold theinherent artisti! ability in the edu!ation of !hildren, sin!e it #ay be!o#e the de!isi$e fa!tor in

the ground%or* of a !ulture that rests on the !reati$e nature of #an.1

Aorbert "iener, 2rofessor of =athe#ati!s at =.I.T., %rites There are fields of s!ientifi! %or*%hi!h ha$e been e<plored fro# the different sides of pure #athe#ati!s, statisti!s, ele!tri!alengineering and neurophysiology, in %hi!h ea!h single notion re!ei$es a separate na#e fro# ea!hgroup, and in %hi!h i#portant %or* has been tripli!ated or +uadrupli!atedO %hile still otheri#portant %or* has been delayed by the una$ailability in one field of results that #ay ha$ealready be!o#e !lassi!al in the ne<t field.14

=edi!al s!ien!e has eli#inated the totality of the natural biologi!al rules in the hu#an body,#ostly by di$iding resear!h and pra!ti!e into #any spe!ialities. >oing intensi$e, #asterly spe!ial-ized %or*, it %as forgotten that e$ery part is still only a pie!e of the entire body.

In all te<tboo*s, %e find that single biologi!al pro!esses ha$e been studied and o$eresti#atedstate#ents #ade about the#. The sy#pto#s of a disease ha$e be!o#e the #ain proble# forresear!h, !lini!al %or* and therapy. The old #ethods %hi!h

1) ee !haefer-i##e#&s The 6nfolding of $rtistic $ctivity, 19). @ni$ersity of California 2ress.er*eley and 3os ngeles. 14 Aorbert "iener, #ybernetics, 19), p. :.

sought to !o#bine all fun!tional parts in a body into a biologi!al entity, ha$e been pushed asideal#ost in$oluntarily, in the !lini!, and espe!ially in institutions of physiology and pathology.?inally, that idea be!a#e $ery re#ote in our thin*ing and therapeuti!al %or*. The opinion of the

best !an!er spe!ialists is, as Lessie Green-stein stated, E#phasis #ust be laid on a direct study onthe side of #alignan!y itself,17 despite the fa!t that his boo* is an e<!ellent !olle!tion of

physiologi!al !hanges in the other organs, espe!ially the li$er. In #y opinion, the appli!ation ofthe !on!ept of totality !an help us find the true !ause of !an!erO it !ould be best %or*ed out in

pra!ti!al e<a#ples, not in ani#al e<peri#ents %here e$ery little sy#pto# is obser$ed singly byitself8.

In the nutritional field, obser$ations for !enturies ha$e sho%n that people %ho li$e a!!ording tonatural #ethods in %hi!h plants, ani#als and hu#an beings are only frag#ents of the eternal!y!le of Aature do not get !an!er. /n the !ontrary, people %ho a!!ept #ethods of #ode#nutrition on an in!reasing s!ale be!o#e in$ol$ed in degenerati$e diseases, in!luding !an!er, in arelati$ely short ti#e.

In later #edi!al history, the best *no%n !an!er-free people %ere the 'unzas, %ho li$e on theslopes of the 'i#alaya #ountains and %ho use only food gro%n in their o%n !ountry and

fertilized %ith natural #anure. I#ported food is forbidden. ery si#ilar is the story of theEthiopians %ho also ha$e natural agri!ulture and li$ing habits %hi!h see#s to pro$e that thistype of agri!ulture *eeps people free of !an!er and #ost of the degenerati$e diseases.

The da#age that #odern !i$ilization brings into our li$es begins %ith the soil, %here artifi!ialfertilization leads to the displa!e#ent of #ineral !ontents and !hanges in the flora of #i!robes!o#bined %ith the e<odus of the earth%or#s. Conse+uently, fre+uent erosion of arable landta*es pla!e. These !hanges bring about, at the beginning, an irritation of the plantsO later they!ause their degeneration, praying %ith poisonous substan!es inse!ti!ides8 in!reases the poisonsin the soil, and these poisons are transferred to plants and fruits.

"e #ust !on!lude fro# these and #any other obser$ations that the soil and all that gro%s in it

is not so#ething distant17 Lesse Greenstein, 4iochemistry of #ancer, p. )9:, 19);.



fro# us but #ust be regarded as our external metabolism, %hi!h produ!es the basi! substan!es forour internal #etabolis#. Therefore, the soil #ust be !ared for properly and #ust not be depletedor poisonedO other%ise, these !hanges %ill result in serious degenerati$e diseases, rapidlyin!reasing in ani#als and hu#an beings. The soil needs a!ti$ityRthe natural !y!le in gro%th andin restR and natural fertilizer, as %e ha$e to gi$e ba!* that %hi!h is ne!essary to replenish the!onsu#ed substan!es. This is the best prote!tion against erosionO it also #aintains the soil&s

#i!robi! flora, produ!ti$ity and life. ?ood planted and gro%n in this %ay #ust be eaten partly asli$ing substan!es and partly freshly prepared, for life begets life. ery signifi!ant are reportsabout Es*i#os %ho get degenerati$e diseases and !an!er in those parts of their !ountry %here!anned food and unnatural nutrition %ere introdu!ed and a!!epted.

>r. lbert !h%eitzer, %ho built a hospital in 3a#barene, Central fri!a, ; years ago,reported in his letters of /!tober, 19);, the follo%ing

=any nati$es, espe!ially those %ho are li$ing in larger !o##unities, do not li$e no% the sa#e%ay as for#erlyRthey used to li$e al#ost e<!lusi$ely on fruits and $egetables, bananas, !assa$a,igna#, taro, s%eet potatoes and other fruits. They no% li$e on !ondensed #il*, !anned butter,#eat- and fish-preser$es and bread. >r. !h%eitzer obser$ed in 19); the first operation onappendi!itis on a nati$e of this region. . . . The date of the appearan!e of !an!er and other

diseases of !i$ilization !annot be tra!ed in our region %ith the sa#e !ertainty as that of appen-di!itis, be!ause the #i!ros!opi! e<a#inations ha$e only been in e<istan!e here for a fe% years. ...It is ob$ious to !onne!t the fa!t of in!rease of !an!er also %ith in!reased use of salt by thenati$es. . , . Curiously enough, %e did not ha$e any !an!er !ases in our hospitals before.

>r. alisbury reported, !on!erning the Aa$a5o Indians, that he had, in ( years, ), Indianad#issions in the hospital, %ith only 44 !ases of !an!er. The death rate a#ong these Indians isone out of 1,, %hile it is about one out of ) a#ong Indians %ho ha$e a!!epted part of thenutrition of #ode# !i$ilization.

The antu population of outh fri!a has ( per !ent pri#ary li$er !an!ers. Their diet, of a $erylo% standard, !onsists !hiefly of !heap !arbohydrates, #aize and #ealy #eals. eldo# do theyha$e fer#ented !o%&s #il*. =eat is eaten only at !ere#onies. T%o physi!ians, >rs. Gilbert andGil#an, studied their nutrition habits in ani#al e<peri#ents and pla!ed stress on the diet of theantus as a !ause of !an!er. The result %as that in al#ost all ani#als the li$er %as affe!ted and( per !ent de$eloped a !irrhosis of the li$er later. "hen an e<tra!t of the li$er of a antu #an%as painted on the ba!* of #i!e, benign or #alignant tu#ors de$eloped.

t the !on!lusion of this !hapter, the reader #ay %ell as* "hat should I do %ith the idea ofthe !on!ept of totality in understanding the !an!er proble# and treat#ent The ans%er is thepre#orbid da#age goes do%n to the basi! $ital pro!esses by poisoning the entire #etabolis#as it %as a!*no%ledged in Ger#any at the International Congress for Gan:heitsbehand9lung der

Geschwulsterkrankungem.*0 2rofessor ieg#und, of the @ni$ersity of =uenster, e<plained thatthis poisoning o!!urs now as a general !onstitutional !ondition %hi!h is !aused by #odern

!i$ilization and %hi!h is not only a preneoplasti! stage but also a pre#orbid general !ondition ofthe hu#an body.1

Therefore, the treat#ent also has to penetrate deeply to !orre!t all the vital pro!esses. "hen thegeneral #etabolis# is !orre!ted, %e !an influen!e again retrospe!ti$e fun!tioning of all otherorgans, tissues, and !ells through it. This #eans that there should be a treat#ent applied %hi!h%ill fulfill the tas* of totality in e$ery respe!t, ta*ing !are of the fun!tions of the %hole body inall its different parts, thus restoring the har#ony of all biologi!al syste#s. The treat#ent %hi!h%ill fulfill this !o#ple< proble# is des!ribed in detail later. 'ere it should #erely be e#phasizedthat the treat#ent has to fulfill t%o funda#ental !o#ponents. The first !o#ponent is tiedeto<i!ation of the whole body %hi!h has to be !arried out o$er a long period of ti#e, until all thetu#ors are absorbed and the essential organs of the body are so far restored that they !an ta*e

o$er this i#portant !leaning fun!tion&& by the#sel$es. If that is not effe!ted to the ne!essarydegree, the entire body be!o#es the $i!ti# of a !ontinuously in!reasing poisoning %ith dire!onse+uen!es !o#a hepati!u#8. e!ondly, the entire intestinal tra!t has to be restored



si#ultaneouslyO

i: 2rofessor ". Mabel, Totality Treatment of Tumorous Diseases, 'ippo*rates erlag, 19),19 2rofessor ieg#und, op. ctt., p. (77.

%ith the restoration of the intestinal tra!t, the #ost i#portant se!retory fun!tions %ill be repaired,as %ell as its !ir!ulation and #otility regulated by the $is!eral ner$ous syste#. In that %ay %e !ana!ti$ate, together %ith other fun!tions, defense, i##unity and healing po%er in the body.I##unity does not #ean here that the body is prote!ted against a spe!ial ba!teriu#O as in aninfe!tious disease, it #eans that no abnor#al !ell !an gro% or de$elop in the body %ith nor#al#etabolis#. ?or that purpose, the degree of restoration of the li$er plays a de!isi$e role. "eshould not forget that a body deto<ified !onstantly through the li$er and the best nutrition !an#aintain an a!ti$e #etabolis# %ith the help of the li$er. Thus, the !on!ept of totality %ill beobeyed in #edi!ine as it is a!ti$e in other li$ing and non-li$ing pro!esses of nature. The sa#e istrue in the field of nutrition.

!!ording to a report at the third International Congress of io!he#istry, *no%ledge of the

interrelationships a#ong nutrients in a diet is essential for an understanding of their +uantitati$ere+uire#ents for the ani#als. @tilization of one nutrient #ay be profoundly affe!ted by the presen!e or absen!e of another. ?or instan!e, under !ertain !ir!u#stan!es the to<i!ity of zin! inrats #ay be !orre!ted by !opper, the presen!e of both #olybdenu# and zin! in any diet #ayresult in signifi!antly poorer gro%th than %as !aused by the addition of these ele#ents separately(8. eleniu# poisoning #ay be redu!ed by arseni! 78O #olybdenu# poisoning in !attle #ay

be !orre!ted by !opper 1(8. Intra$enously ad#inistered #ethionine pre$ented the to<i!ity ofhigh doses of !obalt (18. There is less absorption of iron fro# the gastro-intestinal tra!t in ratsdefi!ient in !opper than in rats supplied %ith !opper ((8.

These obser$ations and #any others reaffir# the finding that an abnor#al !ondition of theani#al #ay not refle!t #erely a lo% or a high le$el of dietary essential, but an e<!ess or a

shortage of one or #ore other nutrients %hi!h interfere %ith the nor#al #etabolis# of theessential dietary !onstituent.

/ne of the #ost stri*ing e<a#ples of this land !on!erns the assi#ilation and storage of !opperin sheep (8. It %as found in ustralia that the addition of ferrous sulphide to the diet lo%eredthe e<pe!ted !opper a!!u#ulation in the li$er by 7) per !ent. Min! gi$en in an a#ount of 1 #g.a day had an effe!t %hi!h %as signifi!ant at the fi$e per !ent le$el, but %hen added in s#allera#ounts %hi!h %ould be a$ailable to sheep grazing nor#al pastures, it had no effe!t on !opperretention.

=olybdenu# gi$en in the for# of a##oniu# #olybdate %as found to ha$e a se$erly li#itingeffe!t, but this effe!t %as only obser$ed %hen the diet also !ontained a suffi!ient +uantity ofinorgani! sulphate....

The nature of the interrelationship of one #i!roele#ent %ith another and %ith other food!onstituents is still i#perfe!tly or not at all understood. It is #y opinion that it is %ithin thes!ope of the bio!he#ists& and nutritionists& #a5or duties to !lear up the obs!urity in this do#ain assoon as possible,(

These e<a#ples are !hosen to illustrate the biologi!al fa!t that not one fa!tor alone or a!o#bination of single fa!tors is de!isi$e, but %hat is de!isi$e is ho% they influen!e the whole

body, mind and soul in their entirety.

To the great !o#ple<ity of the biologi!al fun!tions of the body belongs also its capacity of

adaptation. healthy body !an adapt itself to different types of nutrition. It reabsorbs the ne!es-sary #inerals, $ita#ins and enzy#es as %e *no% fro# e<peri#ents to deter#ine the ti#e for the!lini!al appearan!e of one or another $ita#in defi!ien!y. si!* body has lost this !apa!ity. The

defi!ien!ies !annot be restored as long as the essential organs are poisoned. That is true in !an!eralso, as de#onstrated by !lini!al obser$ations.

Can!er, the great *iller, %ill be pre$ented and !an be !ured if %e learn to understand the eternal



la%s of totality in nature and in our body. oth are !o#bined and ha$e to be united in aneffe!ti$e treat#ent for !an!erO in that %ay %e !an learn to !ure !an!er in a higher proportion, e$enof ad$an!ed !ases. The i#itations of the totality of fun!tions of the %hole body, ho%e$er, also!o#e into a!tion here. The totality of fun!tions is lost if one or another $ital organ is too fardestroyed. I sa%, in se$eral patients, tu#ors in the abdo#en absorbed, and in others, hundreds ofnodules and nodes on the s*in and so#e at the base of the brain eli#inated, but the patients died

of !irrhosis of the li$er in a period of one to three and a half years after%ards.The role of the li$er in !an!er, a!!ording to E%ing, is seen in the fa!t that there are about :) per

!ent of pri#ary hepato#as

( 3. ee*les in Proceedings of the Third <nternational #ongress of 4iochemistry, russels, 19)), p.;7.

and ) per !ent of pri#ary !holangio#as asso!iated %ith !irrhosis of the li$er. The #a5ority ofauthors thin* these !hanges in the li$er ha$e arisen independently of, and probably before thegro%th of neoplas#, as !hanges are diffuse and far re#o$ed fro# the lo!al tu#or. >r. E%ingstates, further#ore, that there is a unifor# gradual pro!ess bet%een nodular hyperplasia of theli$er, #ultiple adeno#as, and #ultiple !ar!ino#as. The usual progress fro# adeno#a to!ar!ino#a is abundantly supplied in literature. These obser$ations %ere $erified in e<peri#ental%or* %ith !ar!inogens %hi!h brought about an apparent progression fro# regenerati$e tissue ofthe li$er to hyperplasia and finally to neoplasia. 6ats fed butter-yello% %ith a ri!e diet sho%ed!irrhosis of the li$er in si<ty days and benign !holangio#as and hepato#as in ninety days, and, in1) days, !ar!ino#as in nearly all rats, da#aging espe!ially the li$er, produ!ing high anaerobi!gly!olysis, al*aline phosphatase and other abnor#alities. The prote!ti$e effe!t of a diet, !onsistingof $ita#ins and !asein on for#ations of e<peri#ental hepati! !ar!ino#a, #ay per#it so#e!o#parison %ith the hu#an disease. It %as found, ho%e$er, that all these results greatly $ary%ith the type of ani#al and also %hether tu#ors %ere gro%n as indu!ed or appeared asspontaneous hepato#as, and $ary e$en #ore so in hu#an hepato#as. Therefore, it be!a#e

i#possible to find a de!isi$e fa!tor in the $ast literature of the produ!tion of these #alignan!ies,as physi!ians loo*ed and are still loo*ing for one spe!ifi! fa!tor only. The solution is that it is nota single fa!tor but generally one of #any fa!tors or an a!!u#ulation of one poisoning for a long

period of ti#e as the e<peri#ents of It!hi*a%a and Fa#agi$a sho%. They needed about nine#onths first to da#age the li$er, *idneys, et!.Ranother proof of rea!tions in their totality. That a$ery strong poison !an da#age the li$er in a fe% days and produ!e a hepato#a in ten days doesnot spea* against it. This !annot be !o#pared %ith the slo%ly progressi$e deterioration in oursyste# !aused by #odern !i$ilization.

?ro# %or* in our !lini!, %e *no% that #any diseases do not appear independent of ea!h other, but #ore as nosologi!al entities. fe% e<a#ples 8 inus infla##ation is fre+uently!o#bined %ith !hroni! bron!hitis or bron!hie!tasis, also %ith laryngitis, nephritis, and other

distant infe!tions. 8 Chroni! !ystitis is fre+uently united %ith appendi!itis. urely, !ystitis isasso!iated %ith a !o#bination of disturban!es in the digesti$e organs. C8 Gall-bladder diseases,#ostly !o#bined %ith li$er alterations, appear together %ith #yo!ardial !hanges and later !ause!irrhosis of the li$er. Conse+uently, %here the defense of the body is essentially redu!ed therefre+uently are ba!terial infe!tions of one or se$eral organs. These !lini!al findings bring us to the!on!lusion that se$eral different types of pathologi!al !hanges #ay o!!ur as the !onse+uen!e of adeep general !ause in the body %hi!h %e !an subordinate under one leading idea, the la% oftotality or the loss or di#inished degree of healing po%er in a #ore !lini!al sense. >espite ourgreat progress in #odern bio!he#istry, %e !annot depart fro# the old 'ippo!ra-tian do!trine ofdire!t and ob5e!ti$e !lini!al obser$ation to !oordinate the# under one !lini!al pi!ture. Ininfe!tious diseases, there %ould not ha$e been trans#issions to neighboring or distant organs, in

#alignan!ies not #etastases, if there %ere enough healing po%er present. Thus, the de$elop#entof disease, its !ourse and healing pro!ess, do not depend so #u!h on the type of tissue or organin$ol$ed, but #ore on the general healing po%er of the entire organis#, united or !entralized in



all its #etaboli! pro!esses for the #ost part !on!entrated in the li$er.Contrary to this !on!ept, our te<tboo*s and 5ournals ha$e separated different diseases and e$en

!an!ers as #alignant tu#ors of the nose and paranasal sinuses, #alignan!ies of the sto#a!h orthe *idney, !an!er of the lungs, et!. There are, of !ourse, differen!es in the type, de$elop#ent,!o#pli!ations, prognosis, et!., but the basi! idea #ust be #aintained that the defense and healing

po%er is an essential part of the whole body and #ust be restored, %hate$er organ or organs #ay

be in$ol$ed or %hate$er !ause the #alignan!y #ay ha$e had. I repeat In general, the re!o$eryfro# a #alignan!y #eans the restoration of the %hole body fro# a *ind of degeneration. In so#e!ases of e<ternal !an!ersRs*in and breastRthe lo!al treat#ent #ay be suffi!ient, but the !on!eptof totality is a superior and farther-rea!hing approa!h as the fa!ts indi!ate in !ases listed in this$olu#e. ee part II8

C-APT1R III

$irections for !eneral 2utrition

I A ?/6=E6 ti#es, nutrition %as traditionally de$eloped by the !onditions of the parti!ular !ountryand histori! e$ents. It %as !ontrolled by religion or states, and #aterially adapted to the finan!esof fa#ilies or indi$iduals. The #odifi!ations in our !ulture and the progress in s!ien!e andte!hni+ue are altering our food !onstantly by its produ!tion in agri!ulture, by preser$ation anddistribution, and also by adaptation to the i#pro$e#ents of li$ing !onditions. These proble#s(1#ust be disregarded here, sin!e I !an gi$e only the essential general dire!tions.

To des!ribe the funda#entals of a general nutrition for healthy people %hi!h guarantees anuninterrupted daily flu< of energy, strength and reser$es for %or* and other duties, is aresponsible tas* and diffi!ult to for#ulate in a !o#prehensi$e for# %ithout #any tables,literature and e<planations. The %ay in %hi!h the funda#entals are des!ribed here is deri$ed

fro# #any long years of e<perien!e %ith people re5e!ted fro# #ilitary ser$i!e or denied lifeinsuran!e.They %ere #ade a!!eptable by follo%ing these dire!tions. Thousands of patients %ere gi$en this

ad$i!e after their re!o$ery fro# !hroni! si!*nesses, and #ost of the# in!luded their fa#ilies inthis pattern of nutrition for #any years. The results %ere satisfa!tory. The #a5ority re#ained ingood health, %ere a!!eptable for life insuran!e and other ser$i!es and in!reased their strength and%or*ing po%er. =y fa#ily and I, too, ha$e follo%ed these dire!tions for #ore than thirty years.

(1 ee !istory of "utrition by lfred ". =!Cann, !ien!e of Eating, >resden, 19(7 and >ie Geschickte

Der %rnahning, by 2rof. 3i!htenfelt, erlin, 191.

This outline per#its suffi!ient #argin for personal li$ing habits, fa#ily feasts and holidays, asone-+uarter of all of the food should be to one&s !hoi!eO the re#ainder should be ta*en for the purpose of prote!ting the fun!tions of the highly essential organsRli$er, *idneys, brain, heart,et!.Rby storing reser$es and a$oiding an unne!essary burden on these $ital organs. To sa$e our

body fro# e<tra %or* in the disposal of e<!essi$e food, espe!ially fats %hi!h are diffi!ult todigest, the destru!tion of poisons, et!, is a pre!aution that #ay pre$ent #any *inds of earlydegeneration, pre#ature old age, and all *inds of a!ute and !hroni! si!*ness in organsso#e%hat %ea*er in origin and de$elop#ent or pre$iously da#aged. That this outline is %rittento pre$ent si!*ness, not to !ure it, #ust be stressed beforehand. The purpose of healing de#andsa #u!h deeper dieteti! en!roa!h#ent and a #edi!ation dire!ted to the pathology of the body&s!he#istry after a diagnosis is established.

The funda#entals %ill not be presented as an enu#eration of !arbohydrates, fats, proteins,$ita#ins, hor#ones and enzy#es as they are des!ribed in physiology te<tboo*s, together %ith thene!essary a#ount of gra#s or !alories. These old te<tboo* arrange#ents #eet only the needs of



a #etabolis# based largely on the entire a#ount of eli#ination, ta*ing into a!!ount only so#eless essential re+uire#ents. s s!ien!e is not yet de$eloped to the point of *no%ing all theenzy#es, $ita#ins and #any biologi!al fun!tions of hor#ones and #inerals, it is safer to usefoods in the #ost natural for#, !o#bined and #i<ed by nature and raised, if possible, by anorgani! gardening pro!ess, thus obeying the la%s of nature. This obser$ation helped the hu#anra!e for thousands of years before any s!ien!e %as de$eloped. In this %ay %e bring in all *no%n

$ita#ins and enzy#es, both the dis!o$ered and the undis!o$ered ones, and espe!ially theun*no%n, to +uote 2rofessor Pollafh, life sti#ulating substan!es, gi$en best as fresh as possibleand not da#aged by refining or preser$ing pro!esses, su!h as !anned food, These !ontain all ofthe ne!essary substan!es in their proper +uantity, #i<ture and !o#position, and are regulated byinstin!t, hunger, taste, s#ell, sight and other fa!tors.

Three-+uarters of the food %hi!h should be !onsu#ed in!lude the follo%ingll *inds of fruits, #ostly fresh and so#e prepared in different %aysO freshly prepared fruit

5ui!es orange, grapefruit, grape, et!.8O fruit saladsO !old fruit soupsO #ashed bananas, ra%grated apples, applesau!e, et!ll $egetables freshly prepared, so#e ste%ed in their o%n 5ui!es and others either ra% or finely

grated, su!h as !arrots, !auliflo%er or !eleryO $egetable salads, soups, et!.O so#e dried fruits and

$egetables are per#itted but not frozen ones.2otatoes are best %hen ba*edO the !ontents #ay be #ashed %ith #il* or soupO they should

seldo# be fried and preferably boiled in their 5a!*ets.alads of green lea$es or #i<ed %ith to#atoes, fruits, $egetables, et!.read #ay !ontain %hole rye or %hole %heat flour, or these #ay be #i<edO it should be refined as

little as possible. /at#eal should be used freely. u!*%heat !a*es and potato pan!a*es are op-tional, as are bro%n sugar, honey, #aple sugar and #aple !andy.

=il* and #il* produ!ts, su!h as pot !heese and other *inds of !heese %hi!h are not greatlysalted or spi!ed, butter#il*, yoghurt and butter. Crea# and i!e !rea# should be redu!ed to a

minimum or restri!ted to holidays i!e !rea# is poison for !hildren8.

The re#aining one-fourth of the dietary regi#e, %hi!h allo%s for persona !hoi!e, #ay !onsistof #eat, fish, eggs, nuts, !andies, !a*es, or %hate$er one li*es best. Ai!otine should be a$oidedOli+uors, %ine and beer should be redu!ed to a #ini#u# in fa$or of fresh fruit 5ui!esO !offee andtea should be !ut to a #ini#u# %ith the e<!eption of the follo%ing teas pepper#int, !a#o#ile,linden flo%er, orange flo%er, and a fe% others.

alt, bi!arbonate of soda, s#o*ed fish and sausage should be a$oided as #u!h as possible, asshould sharp !ondi#ents su!h as pepper and ginger, but fresh garden herbs should be used-onions, parsley lea$es, !hi$es, !elery and e$en so#e horseradish.

s for $egetables and fruits, they should, I repeat, be ste%ed in their o%n 5ui!es to a$oid theloss of #inerals easily dissol$ed in %ater during !oo*ing. It see#s that these $aluable #ineralsare not so %ell absorbed %hen they are out of their !olloidal state.

ll $egetables #ay be used. Espe!ially re!o##ended for their #ineral !ontent are !arrots, peas,to#atoes, %iss !hard, spina!h, string beans, russels sprouts, arti!ho*es, beets !oo*ed %ithapples, !auliflo%er %ith to#atoes, red !abbage %ith apples, raisins, et!.

The best %ay to prepare $egetables is to !oo* the# slo%ly for one and one-half to t%o hours,%ithout %ater. To pre$ent burning, pla!e an asbestos #at under the sau!epan. Fou #ay also useso#e sto!* of soup see >iet spe!ial soup8 or else sli!ed to#atoes #ay be added to the$egetables. This also %ill i#pro$e the taste. pina!h %ater is too bitter for useO it generally is notli*ed and should be drained off. /nions, lee*s and to#atoes ha$e enough li+uid of their o%n to*eep the# #oist %hile !oo*ing. eets should be !oo*ed li*e potatoes, in their 5a!*ets and %ith%ater.8 "ash and s!rub $egetables thoroughly, but do not peel or s!rape the#. au!epans #ust

be tightly !o$ered to pre$ent stea# fro# es!aping. Co$ers #ust be hea$y or !lose fitting.

Coo*ed $egetables #ay be *ept in the refrigerator o$ernight. To %ar# the#, heat slo%ly %ith alittle soup or fresh to#ato 5ui!e.

n e<planation for the i#portan!e of the absorption of these #inerals %as propounded by .



unge, %ho said that there #ust be #ore P or potassiu# in the organs in general than Aa orsodiu#, and that a !ertain relationship bet%een P and Aa #ust be #aintained.

P has to be predo#inant !hiefly %ithin the !ells !alled, therefore, intra!ellular8 %hile Aa has tostay outside the !ells in seru#, ly#ph, !onne!ti$e tissue therefore !alled e<tra!ellular8. 3aterobser$ations led to the opinion that the #inerals do not rea!t singly but in groups. s a!onse+uen!e, >r. 6udolph Peller established the do!trine of t%o #ineral groups, the intra!ellular

potassiu#8 or anodi! group tra$eling to the anode, and the e<tra!ellular sodiu#8 or !athodi!group tra$eling to the !athode under biologi!al !onditions. further !onse+uen!e %as thedis!o$ery that hor#ones, $ita#ins and enzy#es obey the sa#e rule as the t%o #ineral groupsOthis #eans that their fun!tion depends upon the pre$alen!e of the P-group %ithin the !ells of theorgans and tissues su!h as the li$er, #us!les, brain, heart, *idney !orte<, et!., %hereas the Aa-group re#ains outside of the#. The Aa-group is stationed in fluids and tissues seru#, ly#ph,!onne!ti$e tissue, thyroid, bile du!ts, et!. 'ere are also the !athodi! or negati$e $ita#ins andenzy#es, of %hi!h the #ain fun!tions, #etabolis# and storage, are !onfined to this e<tra!ellulargroup.

It is i#possible to $isualize a #etabolis# %ithout the #entioning of hor#ones, $ita#ins andenzy#esO their parti!ular fun!tions shall not be ite#ized. Generally hor#ones gi$e indi$idualityto tissues and !ellsO $ita#ins, or !/-enzy#es, help #etaboli! differentiation and $itality, andenzy#es bring about, step by step, #etaboli! a!ti$ity and spe!ifi! digesti$e pro!esses generaldehydro-genation and o<idation8, pre$ent inter#edial #etabolites of %hi!h so#e are poisonousand #ay lead to !atara!t, stone for#ation or !hroni! infla##ations. The nor#al#etabolis#.depends upon the !o#bined fun!tion of all of the#, e$en if ea!h of the# possesses$arious %ays and #eans of fun!tioning.

To the P-group belong about 4 per !ent of body tissues and to the Aa-group per !entO 1 per !ent are on the borderline. ll of the# are *ept in their proper pla!e, probably by #eans oftheir ele!tri!al potentials. >uring the day, so#e Aa penetrates the potassiu# tissues, and this isfollo%ed by !hloride and %ater, a pro!ess %hi!h brings on fatigue, a little hea$iness or s%elling.

t night, it is reabsorbed and in the #orning it is eli#inated in urine, and the person feelsrefreshed.

These biologi!al rules are $ital for the maintenance of health

inas#u!h as a defi!ien!y, defe!t or !hange #eans si!*ness. l#ost all a!ute and !hroni!si!*nesses begin %ith an in$asion by Aa, !hloride and %ater of the anodi! organs, !ausing theso-!alled ede#a produ!ed by poisons, infe!tions, trau#a, et!. It see#s to #e, therefore, that

so#e tables %ith short e<planations are indispensable to #ar* ho% deeply the fun!tions of the#inerals are i#planted in the ani#al&s body. (( . hobI, Mineral Metabolism, 199, pp. 19-(.



Table 1 represents the #ineral groups in the de$elop#ent of the body fro# fetus to adult, pro$ing that the fetus, ta*en as a %hole, is first an ani#al pre$alent in Aa-group but later Aa,!hloride and %ater de!rease fro# 11( #illie+ui$alents Aa to ;:, %hile fro# the P-group, Pin!reased fro# )1 #e+. to 4:O phosphorous in!reases fro# 49 to 7;, et!. This relationship has to

be #aintained throughout our life be!ause, as #entioned abo$e, the fun!tion of the essentialhor#ones, $ita#ins, and enzy#es is adapted and based on that PAa relationship or better, on the

t%o groups of P and Aa, the p' !ontent, !o-enzy#es, et!.Table ( indi!ates the great i#portan!e of the PAa relationship in %o#an&s #il* !o#pared %ith

the #il* of rats and !o%s

Tables ; and ) #ay pro$e that this relationship is re$ersed in si!*ness. "hile the tissues lost the po%er to retain the P-#inerals and gly!ogen, these de!reased see Table ;8 fro# (.4 to ).:,then sodiu# !hloride and %ater in$ade the tissue !ells fro# e<tra!ellular fluids, thus !ausing anin!reasing rise in the #il* of Aa fro# 1.( to ;(.7

( Ibid., p. 7. (; Ibid., p. (7.



The hu#an body has a %onderful reser$e po%er and #any possibilities of ad5ust#ent, but the best defense apparatus is a 1 per !ent fun!tioning #etabolis# and reabsorption in the intestinaltra!t in !o#bination %ith a healthy li$er. 2eople #ay !on!lude, needlessly, that it is noti#portant to pla!e so #u!h e#phasis on nutrition. This #ay be so under nor#al !onditions and ifthese persons are not da#aged through heredity, !i$ilization, si!*ness, trau#a or othera!!u#ulations ni!otine and other poisons8.

Ci$ilization has partially ta*en a%ay this natural besto%al. E<peri#ents on test groups to produ!e different $ita#in-defi!ien!ies by o#itting food !ontaining these $ita#ins sho%ed thatone third !an be #ade defi!ient in about four #onths and t%o thirds in si< #onthsO only fi$e tosi< per !ent resisted ten #onths of defi!ient feeding here in the @nited tates. These nutritionale<peri#ents and others sho% that only a #inority possesses a !o#plete inta!t reabsorptionapparatus and at the sa#e ti#e

(E. 2. ?is!her, 5phthalmologic. 11;1, 19;7.

enough ad5ust#ent and reser$e po%er for healthy and unhealthy periods in their li$es.It is not ne!essary for healthy persons to !are so #u!h about enough or too #any

!arbohydrates and proteins, and their !alori! $alue should be ignored. 'o%e$er, one !annotignore the absolutely ne!essary #inerals, $ita#ins and enzy#es in their #ost natural!o#position and in suffi!ient a#ounts for a relati$ely long ter# and re#ain unpunished. The#inerals ha$e to be in the tissues %here they belong, as they are the !arriers of the ele!tri!al

potentials in the !ellsO and there they enable the hor#ones, $ita#ins and enzy#es to fun!tion properly. This gi$es the body the best %or*ing po%er and reser$es for a sound #etabolis# andlife.

@==6F

The best ad$i!e is to use fresh $egetables and fruit organi!ally gro%n as #u!h as possible.=others should pay #ore attention to their !hildren and their *it!hen. /ne&s o%n garden %ould

be a great help in su##erti#e.aluable and pra!ti!al infor#ation !an he found in the follo%ing publi!ations

oil and =en. =earbook of $griculture, 19:?ood and 3ife. =earbook of $griculture, 1995rganic Gardening, L. I. 6odale, 'ano$er 'ouse, Garden City, A. F., 19))5ur Daily Poison, 3eonard "i!*enden, The >e$in-dair Co., A. F., 19))5ur Plundered Planet, ?airfield /sborn, 3ittle ro%n Co., oston, 19;:The iving 'oil, E. . alfour, ?aber ?aber 3td., 3ondon, 19;:

!unsa, 6alph ir!her, 'ans 'uber, ern, %itzerland, 19)( &oad to 'urvival, "illia# ogt, "#. loane sso!iates, A. F., 19;: !andbuch der Diaetetik, Lohannes !ala, ?ranz >euti!*e, "ien, 19);

'tudies in Deficiency Diseases, 6obert =!Carrison, =.>., 3ee ?oundation,=il%au*ee , "is., 19;) Degeneration &egeneration, =el$in E. 2age, >.>.., 2age

?oundation, t.



2etersburg, ?la., 19)1 ;hat Price #ivili:ation> Charles Eliot 2er*ins, =odern !ien!e 2ress,"ashington, >.C., 19;4 The Drama of 7luorine, $rch %nemy of Mankind, 3eo pira, =.>., 3ee

?oundation, 19) Prolongation of ife, >r. le<ander . ogo#olets, >uel0 loan 2ear!e,In!., A. FV 19;4 "utrition 4- Physical Degeneration, "eston . 2ri!e, 2aul . 'oeber, 19;9

!unger 'igns in #rops, y#posiu#. #eri!an o!iety of grono#y ". Pollath, ?ur %inheit

der !eilkunde. 'ippo*rates erlag, tuttgart. 19;( ". Pollath, Die 5rdnung 6nserer "ahrung,

'ippo*rates erlag, tuttgart, M%eite uflage, 19)G. $. "endt, @ost und @ultur. Thie#e, 3eipzig 194=. ir!her-enner, %rnaehrungskrankheiten. "endepun*t-erlag. Mueri!h

und 3eipzig. ?uenfte uflage. 19;. >. 3i!hti-$. ras!h und . Punz-ir!her, Die @linische

4edeutung der

7rischkost. 'ippo*rates Meits!hrift. .11. 19)4 >uane ". 2robst, =.>. The 2atient is a @nitof 2ra!ti!e, 2art /ne,

"ature of Disease. Charles C. Tho#as, pringfield, 111. 19: !andbook of "utrition. $

y#posiu#. #eri!an =edi!al sso!iation, 19; The Aitamins. $ y#posiu#. #eri!an=edi!al sso!iation. 199 'ymposium 5n &espiratory %n:ymes. The @ni$ersity of "is!onsin2ress.

19;( Ed%ard 'o%ell, The 'tatus of 7ood %n:ymes in Digestion and Metabolism,

Aational Enzy#e Co#pany. 19;4 Parl =yrba!*, The %n:ymes. !ade#i! 2ress In!., Ae%For*. 19)1 . I. /parin, The 5rigin of ife on the %arth. !ade#i! 2ress In!., Ae%

For* 19)7, ee espe!ially The %or* of 2asteur, p. (:, Con!lusion, p.;:7 =a< Gerson, =.>., ?eeding the Ger#an r#y, "ew =ork 'tate Bournal

of Medicine. 1;71.;1.19;1 RR-. >ietary Considerations in =alignant Aeoplasti! >isease, &eview of

Gastroenterology. ol. 1(, Ao. 4, pp. ;19 to ;() Ao$.->e!. 19;)- -. Effe!t of a Co#bined >ietary 6egi#e on 2atients %ith =alignant

Tu#ors, %xperimental Medicine and 'urgery. Ae% For*, ol. II,

Ao$. ;,19;9- -. Ao Can!er in Aor#al =etabolis#, Medi:inische @linik, =uni!h,Lan. (9, 19);, Ao. ), pp. 17)-179

W . Can!er, a 2roble# of =etabolis#, Medi:inische @linik, =uni!h,Lune (), 19);, Ao. (4 RR. Can!er 6esear!h, 'earings before a ub!o##ittee of the

@nitedtates enate, . 1:7). Luly 1, (, and , 19;4

C-APT1R I.

$evelopment of the Com&ined $ietary Regime inCancer 3Survey4

T'E 'IT/6F of the de$elop#ent of the !o#bined dietary regi#e in !an!er follo%s briefly fterthe dieteti! treat#ent of lung tuber!ulosis %as established 19(7-19(:8 I treated, during 19(:-(9,#y first three !an!er !ases all %ith fa$orable results. The dietary regi#e as it %as used intuber!ulosis !onsisted essentially of a saltless, properly prepared diet of fresh fruit and $egetables,

predo#inantly ra%, finely grated, arid #any freshly prepared 5ui!es, su!h as orange, grapefruit,and espe!ially, apple and !arrot 5ui!es. ?re+uent ene#as %ere applied and =ineralogen Sa !o#-

position of #inerals8 %as ad#inistered. 3ater there %as added daily butter#il*, pot !heese,yoghurt and t%o ra% egg yol*s. stirred up in orange 5ui!e.

=y first !an!er !ase %as a !ar!ino#a of the bile du!ts %ith t%o s#all #etastases of the li$er.



T-1 T-15R6

=F T'E/6F is not presented to gi$e a general s!ientifi! e<planation of the !an!er proble#, norto !o#pare it %ith the #any e<isting theories and e<planations. It is supposed to be a guide%hi!h helps physi!ians to apply the treat#ent properly. The theory %as deri$ed fro# !lini!al

obser$ations during %hi!h %as re!orded %hat %as #ost !hara!teristi! of the disease and %hatsee#ed to be #ost de!isi$e in the !ourse of the treat#ent. In short, it is this "hat is essential isnot the gro%th itself or the $isible sy#pto#sO it is the da#age of the %hole #etabolis#,in!luding the loss of defense, i##unity and healing po%er. It !annot be e<plained %ith norre!ognized by one or another !ause alone.In #y opinion, !an!er is not a proble# of defi!ien!ies in hor#ones, $ita#ins and enzy#es. It isnot a proble# of allergies or infe!tions %ith a $irus or any other *no%n or un*no%n #i!ro-organis#. It is not a poisoning through so#e spe!ial inter#edial #etaboli! substan!e or anyother substan!e !o#ing fro# an outside, so-!alled !ar!inogeni! substan!e. ll these !an be

partial !ausati$e agents in #an, !ontributing ele#ents, !alled se!ondary infe!tions, et!. Can!er isnot a single !ellular proble#O it is an a!!u#ulation of nu#erous da#aging fa!tors !o#bined indeteriorating the %hole #etabolis#, after the li$er has been progressi$ely i#paired in itsfun!tions. Therefore, one has to separate t%o basi! !o#ponents in !an!erO a general one and alo!al one. The general !o#ponent is #ostly a $ery slo%, progressing, i#per!eptible sy#pto#!aused by poisoning of the li$er and si#ultaneously an i#pair#ent of the %hole intestinal tra!t,

later produ!ing appearan!es of $itally i#portant !onse+uen!es all o$er the body. The pro!ess

in the pre-stage of !an!er has not been pro$en !lini!ally. That #ay be $ery diffi!ult, e$eni#possible, as li$er da#age is #ost probably a predisposition of #any other degenerati$ediseases. In !an!er, one or the other li$er fun!tion #ay be predo#inantly #ore da#aged or!o#bined %ith so#e other disturban!e in another organ. 'o%e$er, %e should *eep an eye on theli$er as the first e<peri#ents of Fa#agi$a and It!hi-*a%a de#onstrated that !an!er de$eloped,

after the liver, the *idneys and ly#ph glands sho%ed pathologi!al !hanges. In the poisoning ofthe li$er, !lini!al sy#pto#s are not noti!eable for a long period of ti#e, e$en for #any years.

The li$er is the largest single organ in the body and is surpassed by none in the #ultipli!ityand i#portan!e of its $arious physiologi! a!ti$ities. !!ordingly, the state of the li$er and le$elof its fun!tional effi!ien!y are of great signifi!an!e to the general bodily e!ono#y both in healthand in disease.(9 The li$er %eighs se$en to ten pounds and has a fun!tional !apa!ity far in e<!essof ordinary needs. efore the fun!tional reser$es are used up, it is $ery diffi!ult to dete!t adeterioration of fi$er fun!tion, The li$er is a dyna#i!, a!ti$e organ, and has #anifold fun!tions.=ost of these are inti#ately asso!iated and !orrelated %ith the a!ti$ities of the other organs. It isi#possible to test a li$er by a single fun!tion, e$en by se$eral, to find the degree of hepati!deterioration. That is the reason %hy the initial de$elop#ent of !an!er re#ains hidden for su!h a

long ti#eO this inter$al #ay be !alled the pre-!an!erous or pre-sy#pto#ati! period. If a persongets ner$ous, feels %ea*er, has less energy and loses %eight during that ti#e, no physi!ian !an#a*e a spe!ifi! diagnosis as a !an!er test does not e<ist and there is no early spe!ifi! sy#pto#!o#ple<. 2hysi!ian and patient ha$e to %ait until a tu#or is far enough de$eloped in one oranother area of the body to sho% lo!al sy#pto#s or signs %hi!h !an no longer be o$erloo*ed!lini!ally. This is %hen %e use all #odern e+uip#ent su!h as N-ray e<a#inations, bron!hos!opy,!ystos!opy, and 2apani!olaou tests at e$ery spot %here %e !an rea!h the different organs. u!hsy#pto#s !an be !aused by s#aller or larger destru!tions %ith se!retions or bleedings fro# thelungs, sto#a!h, intestinal tra!t, *idneys, bladder, uterus and other organs or #etastati! glands.There #ay be a

(4 ". . >. nderson, Pathology, 19;:, p. :41.

great $ariety of spe!ial signs fro# the brain, spinal !ord, bones and other sy#pto#s. ?inally, in



so#e !ases, a diagnosis !an be established only %ith the help of e<ploratory operations.The s!ientifi!ally a!!epted #ethod is that these sy#pto#s alone %ill be treated locally

%here$er they appear. That is %hat %e physi!ians learn and ho% %e are trained in uni$ersity!lini!s. ll resear!h %or* adheres #ostly to these lo!al sy#pto#s. This is, in #y opinion, thereason %hy de!isi$e progress in !an!er treat#ent has been i#peded, espe!ially in the last )years, during %hi!h #odern #edi!ine #ade re#ar*able progress in #any other fields.

The lo!al !o#ponent is !aused, in #y opinion, by abnor#al !ells, i##ature !ells, for#erlyda#aged !ells, transitional !ells %hen they fall ba!* or are for!ed to fall ba!* into a type ofe#bryoni! life, be!ause they are no longer supported suffi!iently by the a!ti$ated ionized8#inerals of the potassiu# group and a suffi!ient a#ount of rea!ti$ated o<idizing enzy#essi#ultaneously united %ith the nor#al regulations of hor#ones, $ita#ins and. the i#pulse of anor#al fun!tioning $is!eral ner$ous syste#. ?inally the fun!tions of sub!utaneous, reti!ularly#ph !ell tissue and reti!ulo-endothelial syste# are di#inished in fun!tion and defense po%er.

s #entioned abo$e, the general !o#ponent is i#portant, and it %ill be treated. It !o#prises#ainly the deterioration of the essential organs of the digesti$e tra!t, !hiefly the fi$er. There, theda#age is done by a per#anent daily poisoning brought about by our #odern !i$ilization. Thisstarts %ith the soil %hi!h is denaturalized by artifi!ial fertilizers and depletion, thus gradually

redu!ing the top soil. In addition, the soil is poisoned by sprays %ith >>T and other poisons. sa !onse+uen!e, our nutrition is da#aged by a de!rease in the i#portant P-group !ontent of fruitand $egetables gro%n on su!h poisoned soil. ?urther#ore, the food substan!es are da#aged asthey are refined, bottled, blea!hed, po%dered, frozen, s#o*ed, salted, !anned, and !olored %ithartifi!ial !oloring. Carrots are sold in !ellophane bags after ha$ing been treated for better

preser$ation. /ther foods !ontain da#aging preser$ati$esO finally, !attle and !hi!*ens are fed orin5e!ted %ith stilbestrol to a!!u#ulate #ore %eight and be +ui!*ly ready for #ar*et.

If %e approa!h the !an!er proble# fro# a #ore pra!ti!al

ie%point - the !lini!al side - based on the !on!ept of totality, %e learn t%o things firstly, %eha$e to li$e near nature,(7 a!!ording to our natural de$elop#ent. e!ondly, s!ien!e !annot help

us to sol$e the deep, underlying !ause of !an!er.

(:

The #ost basi! property of the heart is that it is a #us!le, and the !hief property of #us!le isthat %e do not understand it. The #ore %e *no% about it, the less %e understand and it loo*s asif %e %ould soon *no% e$erything and understand nothing. The situation is si#ilar in #ostother biologi!al pro!esses and pathologi!al !onditions, su!h as the degenerati$e diseases !an!er8.This suggests that so#e $ery basi! infor#ation is #issing. The story of #yosin #ay illustrate this

point. It see#s as if %e *no% too little about the life pro#oting substan!es 3ebensstoffe Ras ".Pollath has !alled the#,(9 re!ognizing their enor#ous i#portan!e.

lbert !h%eitzer re!ognized the greatness of the a%e for life or the need to ha$e the deepestrespe!t for e$erything that is ali$e >ie Ehrfur!ht $or# 3eben8. The li$ing being, %hether largeor s#all, plant or ani#al, is in e$ery respe!t perfe!tly !reated or de$eloped, in all its fun!tions

and in all its parts, best in its totality.E$erybody respe!ts and needs s!ien!e, resear!h, and laboratory %or*, but their !on!lusions

should not be o$eresti#ated. 2arti!ularly, the dire!tion of therapeuti! a!tion should al%ays be based on the idea of the body as an entity, %hi!h has to be supported and restored in its silent perfe!tion.

It is unne!essary to understand the %hole life in its #inute biologi!al parti!les and effe!tRbutit is ne!essary that, for the proble# of therapy, the entire si!* hu#an organis# be atta!*ed in itstotality, espe!ially in degenerati$e diseases. It %ould be a great #ista*e to apply the therapy onlyas far as %e understand the !orresponding biologi!al rea!tions or as far as they !an be pro$en inani#al e<peri#ents. In parti!ular, in degenerati$e diseases and in !an!er, %e should not apply asy#pto#ati! treat#ent or only one that %e !an fully understandO %e need a treat#ent that %ill

!o#prise the %hole body as far as %e *no% or (7 ee G. ". eadle, !ien!e, Lan. ;, 19)7, o0. 1(), Ao. (4.(9 ee lbert !ent-Gyorgyi, & ioenergeti!s, 'cience, Ao$. (, 19)4, ol. 1(;, Ao. ((7.



pathologi!al !hanges, together %ith the *idneys, spleen and the ly#phati! apparatus. The long period %as re+uired to poison the li$er, before the da#aged !ells !ould perfor# the #utationinto !an!er.

nother e<peri#ent pro$ed that !an!er is not a !ontagious disease. 3ater, %e learned totransplant !an!er under spe!ial

: ee sur$ey arti!le of le<ander 'addo%, The io!he#istry of Can!er, in the $nnual &eview of

4iochemistry, ol. (;, p. 4:9.:;J ee 6udolf !hoenhei#er, The Dynamic 'tate of 4ody #onstituents, 'ar$ard @ni$ersity 2ress,

19;(.

!onditions in ani#als. 3eo 3oeb %as the first %ho su!!eeded in ino!ulating rat sar!o#a of thethyroid gland to se$eral generations of rats.:)

The +uestion %hether hu#an beings !an be i##unized against !an!er has to be ans%erednegati$ely. There is no a!ti$e nor passi$e i##unization thin*able in a body %here !an!er isgro%ing by itself as a part of its o%n organis#. The type of !an!er #ostly $irus tu#ors 8 against%hi!h i##unization su!!eeded do not e<ist at all in hu#an beings.:

The first physi!ian %ho tried to transplant !an!er %as #ost probably >r. L. 3. libert, a fa#ous

surgeon in 2aris at the ti#e of Aapoleon. /n /!tober 17, 1::, >r. libert perfor#ed ane<traordinary operation at the 'ospital of t. 3ouis in 2aris. 'e too* !an!erous #aterial fro# afe#ale breast tu#or, bro*e it into s#all parti!les and finally #ade an e#ulsion %hi!h he in5e!tedinto hi#self and three of his students. se$ere fe$erish infla##ation appeared and lasted a fe%daysO there %as no other rea!tion. fe% days later, >r. libert repeated the sa#e e<peri#ent onhi#self and a !olleagueRagain no other results.

"e *no% that Aapoleon, %hose father died of !an!er of the sto#a!h, %as $ery #u!h interestedin the !an!er proble# and assu#ed that he %ould die of the sa#e disease, %hi!h he did. 'edis!ussed the sub5e!t $ery often %ith his physi!ian >r. 3u!ien Cor$isart.

In re!ent years, >r. E. "eiss of Chi!ago tried to in5e!t a s#all a#ount of %atery e<tra!tobtained fro# hu#an !an!erous tissue into !an!er patients, on!e a %ee* for si< !onse!uti$e

%ee*s. The result %as an in!rease in appetite and a slight gain in %eight for a short ti#e only.?ro# these first e<peri#ents and fro# nu#erous later ones, %e learned ho% diffi!ult it is to

#a*e !an!er transplantations effe!ti$e in the sa#e type of ani#al and ho% #u!h #ore diffi!ult itis to transplant it into other types.

The +uestion %hether the healthy body has the po%er to pre$ent its ta*ing in!orporation8%as negle!ted for a long ti#e, in the follo%ing respe!t in general %e *no% that the healthy bodyhas the po%er to defend itself against in$asion by foreign

:) L.=. 6esear!h (:1). 191.

:4 ee P. '. auer, Das @rebsproblem, 19;9, pp. ;:-;;1

bodies or li$ing ba!teria, !o!!i, $iruses, et!. by a defense rea!tion, or to destroy the# after theyha$e entered the body, by an infla##atory rea!tion as a #eans of healing.

I repeatRa defense or healing rea!tion o!!urs in the healthy body %hen !an!er tissue ore<tra!ts of !an!er tissues are in5e!ted. 'o%e$er, the rea!tion %as different in !an!er patients.There, all different types of e<peri#ents had only a #ini#u# or te#porary effe!t, as the!an!erous body had lost its defense and healing po%er.

e$eral outstanding authors, su!h as ugust ier, 2ir+uet, and $on erg#ann, thought the#alignan!ies !ould be in!luded in the proble# of the infla##ation, sin!e the !an!er body !ouldno longer bring about a nor#al infla##atory healing rea!tion. In the beginning, 6udolf ir!ho%thought that the !hroni! infla##ation %as also a pro!ess of degeneration, %hile today the infla#-#atory pro!ess is re!ognized as a #esen!hy#al rea!tion, %hi!h #ay turn out to the ad$antage or

disad$antage of the body.G. $on erg#ann, head of the =edi!al @ni$ersity Clini! in erlin and 2resident of the erlin=edi!al sso!iation, %as the first to e<a#ine at his !lini! the fun!tional !he#i!al !hanges in



!an!erous tissue and !an!er-bearing bodies in their rea!tions, but he did not dare to use thesefindings for therapeuti!al e<peri#ents. 'e e<plained in his boo* that there are differen!es in the$arious types of infla##atory #etabolis# %hi!h %ere studied in details at his hospital.7 The !ellsin an infla##atory e<udate ha$e aerobi! gly!olysis e$en greater than the nor#al blood leu*o!ytes,%hile the leu*o!ytes in leu*e#ia ha$e only an anaerobi! #etabolis#.:

e!ause of the i#portan!e of these findings for the ne% approa!h to the !an!er proble#, i.e.,

regarding it as a disturban!e of the total #etabolis# and its essential fun!tions, I should li*e to+uote a passage fro# >r. $on erg#ann&s boo*

E$en if a syste#ati! therapeuti! use of this idea is i#possible at this ti#e, a !an!er #etabolis#starts %here the body is no longer able to produ!e a healing infla##ation. It is possible to sho%distin!tly antithesis of the t%o #etabolis#s in their rea!-

7 !# von Bergmann Pathologic, pp. 17-17;.::- ee 2es!hel .3eu*n!osten, 7lin# /o#" '(+8" 2o# 9+" and Ruth Lohmann :7re&sstoff;echsel":

7lin# /o#" 2o# +(#

tions. E<peri#ents are #ade by 6uth 3oh#ann under super$ision of >r. Pe#pner %hi!h pro$ethat sli!es of tissue, ta*en fro# #alignant rat tu#ors or hu#an !an!er tissues, are *illed fast in aninfla##ation e<udate si#ply be!ause the spe!ifi! #etabolis# of the !an!er !ell !annot be#aintained in those surroundings. The e<a!t $alues for sugar, bi!arbonate and the a!id-degree#easured by the p' figure sho% that no !an!er !ell !an li$e there any longer. ee Table II, Ao.18

Table ( !learly sho%s the +ui!* eli#ination of the !an!er !ells in infla##ation fluid after afe% hours, %hile they %ere perfe!tly able to li$e in seru#. It #eans that %here the infla##ation#etabolis# begins, the !an!er #etabolis# stops and the !an!er !ells ha$e to die in the area ofsu!h a fa$orable infla##ation #etabolis# %ith high o<idation po%er.

?ehleisen 1:(8, Coley 1:9(-19198 and others !ould not enfor!e a suffi!ient infla##atoryrea!tion by ino!ulating infe!tions or infe!tious #aterial in !an!er patients %in!h %ould produ!eenough high fe$er for healing rea!tion. >rs. libert, "eiss, >uro$i!, Prebiozen8 and others did

partially su!!eed in their long endea$ors to produ!e a suffi!ient defense rea!tion in the body byino!ulating !an!erous tissue or e<tra!ts fro# !an!er tissues, infe!tious #aterials, et!.

Thus, %e begin to re!ognize the disease of !an!er as a pathologi!al degenerati$e $ariation of thetotal #etabolis#, si#ilar to $ariations of other degenerati$e diseases.

The therapeuti!al endea$ors !on!entrate on three essential ite#s

18 far-rea!hing and #aintained deto<i!ation.(8 6estoration of the %hole enteral #etabolis#, in!luding the li$er, as far as possible.



pro!esses.;( 'e also thin*s that the general disease is present before the tu#or appears as2rofessor Mabel assu#es.

"e should not regard the tu#or as a spe!ial type of disease. That !annot be pro$en by the fa!tthat not only the ripe and unripe tu#or !ells !an be influen!ed by the sa#e !onditions of the#etabolis#, but also #any other seg#ents are influen!ed at the sa#e ti#e and in the sa#e %ay.I obser$ed the sa#e !lini!al appearan!es in !an!er patients %ho also i#pro$ed or restored

!o#pletely se$eral !hroni! diseases in the organs during the

;( 2rof. Ernest 3eupold, The 'ignificance of 4lood #hemistry in &egard to Tumor Growth and Tumor

Destruction, Georg Thle#e erlag, tuttgart, 19);, p. ((.

treat#ent su!h diseases as !hroni! arthritis, !hroni! sinusitis, !hroni! gall bladder disorders,arterios!lerosis, asth#a, !raurosis $ul$ae, e!ze#as, et!.

o#e !hroni! or degenerati$e diseases, in!luding !an!er, ha$e been negle!ted in the last years. Can!er %as !onsidered in!urable in the #inds of physi!iansO therefore, it al#ost see#ed

not %orth%hile to put intensi$e %or* into it. Internal physi!ians left !an!er %or* to surgeons, biologists, and pathologists. These, ho%e$er, %ere deeply interested in finding out %hat !auses!an!er and %hat it does in ani#als and hu#an beings in the field of their !o#peten!e, biologi!alor !he#i!al spe!ialty.

2atients ha$e reported that after unsu!!essful operations and N-ray treat#ents that physi!iansga$e the# sedation only, thereby adding ne% poisons to the large a#ount %hi!h the disease is!ontinuously produ!ing.

"hen papers report that a surgeon re!o##ends #ore operations for the purpose of pre$entingthe loss of the patient to the non-physi!ians, %e all should feel gra$ely !on!erned. u!h aber-rations fro# s!ientifi! beha$ior should be an in!enti$e to apply any pro#ising treat#ent,regardless of %ho %or*ed it out or ho% diffi!ult it #ay be. "here li$es are at sta*e our surgeons

and physi!ians should not re!o##end only surgery or non-surgery, but should !onsider all#eritorious possibilities. /f !ourse, this boo* des!ribes #any obsta!les %hi!h ha$e to beo$er!o#e in this #ode# !i$ilization.

C-APT1R .II

Paracelsus% $ietary Regime<

I A 'I %or*s, 2ara!elsus 1;9-1);18 e#phasizes that #an is a #i!ro!os# in the #a!ro!os# ofthe uni$erse, depending on all the la%s %or*ing therein. oth #en and nature ha$e a fre+uent andre!ipro!al influen!e upon one another %hi!h rea!hes into the s#allest parti!les through %ater,earth, sun, season, #o$e#ent of stars, food, soil, et!. bo$e all %e #ust realize that there is noth-ing in hea$en or on earth that does not also e<ist in #an hi#self. "e !an say, therefore, that thesyste# %hi!h go$erns the hu#an being itself is Great Aature. ol. I, p. ()8 The body needsnutrition through %hi!h it is bound to nature. 'o%e$er, that %hi!h %e ha$e to gi$e to the bodyas nutrition also !ontains to<ins and da#aging substan!es. In order to deal %ith the har#fulthings %hi!h %e ha$e to use to our disad$antage, the 3ord ga$e us an al!he#ist sto#a!h8 not toabsorb the poisons that %e eat together %ith the good nourishing food, but to separate it fro# thefa$orable substan!es.

The hu#an being has to a!+uire *no%ledge of %hat to eat and drin*, and %hat he has to %ea$eand %ear, be!ause nature ga$e hi# the instin!t of self-preser$ation. ?or the things that one doesfor the prolongation of one&s life are ordained by Great Aature. If so#eone eats %hat is useful for



his health and a$oids other things that #ay shorten his life then he is a #an of %isdo# and self-!ontrol. ll that %e do should ser$e to prolong our life.

=any undis!o$ered +ualities are hidden in our nutrition and

K Ta*en fro# the translation by >r. . s!hner, Ae% For*Rerlag $on Gusta$ ?is!her. tuttgart,19.

;9

they are able to !ountera!t the da#aging for!es of the stars su!h as sunburn8. !!ording to2ara!elsus, so#e of the Great Aature&s for!es help produ!e ani#al urges and bad instin!ts in #an%hi!h God-gi$en reason and 5udg#ent !an !ountera!t and o$er!o#e. ?ood and drin* !an !ause#orbid !onditionsO he belie$es that nutrition aids the de$elop#ent of all !hara!teristi!s good or

bad, gentle or !ruel. =an in his !hara!ter and disposition rea!ts to his food li*e the soil tofertilizer. s a garden !an be i#pro$ed %ith the right fertilizer so !an #an be helped %ith theright food, In the hand of the physi!ian nutrition !an be the highest and &est remedy#

3Arcanum4 Diet must be the basis of all medical therapy, yet diet should not be a treatment in

itself. ut it ;ill enable Great Aature to de$elop and fully unfold its o%n healing po%er. ute$en nutrition is sub5e!t to the influen!e of hea$en and earthO therefore, the physi!ian #ust study

its !o#binations in order to apply the# at the right ti#e and brea* the po%er of the disease. II, p. 4998

>iet should also be pres!ribed differently for ea!h se<, for it should not ser$e to a!!u#ulate blood and flesh. It should rather effe!t the eli#ination of the foodstuffs %hi!h ha$e spoiled and poisoned blood and flesh. Therefore #edi!ation and spe!ial nutrition are ne!essary. In thetreat#ent of a patient the physi!ian #ust !onsider that the nutrition as %ell as the #edi!ation isin agree#ent %ith the patient&s se<, this is not ne!essary in the !ase of a healthy person.

2ara!elsus gi$es greatest !onsideration to diet in !onstitutional diseases %hi!h, in the %idestsense, !ould also be !alled diseases of the #etabolis# he !alls the# the tartari! a!id or stone-for#ing diseases8. Tartari! a!ids are !ontained in our food but they do not belong in hu#an

beings. These parti!les are tiny pie!es of #inerals, sand, !lay or glue %hi!h in the hu#an body

turn into stone. The hu#an sto#a!h is not !reated %ith the ability to separate these substan!es.This separation is a!hie$ed by the subtile sto#a!hs %hi!h are built into the #essenteriiun,li$er, *idney, bladder and all other intestines. If their fun!tion !eases, $arious diseases %ill resultin the organs !on!erned through the !oagulation of these tartari! substan!es by the ani#al spiritsof #an the sper#a or piritus des alzes8. There%ith 2ara!elsus puts into this group ofdiseases the stone-for#ing ones, as %ell as the 2hleboliths, $as!ular !ra#ps, dental diseases,!hroni! digesti$e disturban!es, sto#a!h and intestinal ul!ers, diseases of the li$er and spleen,gout and arthritis, bron!hie!tasis and bron!hitis, not tuber!ulosis8, for he separates it fro# thisgroup, at least in its #ore serious for#s8 and finally brain diseases. t that early period2ara!elsus had re!ognized that the endogen and e<ogen sti#ulants are $ery !losely !onne!ted in!onstitutional diseases. 'e pla!es the e<ogen sti#ulants e<!lusi$ely into nutrition and %ith that

he !o#es !lose to our #odern thoughts in respe!t to a therapy of nutrition. "e !onsu#e tartari!a!id #ainly in legu#inous plants and grains, stal*s and roots. Those transfor# into a toughs%eet sli#e, %hile #il* foods, #eat and fish !ontain a !lay-li*e #ass, %ine for#s a tartar%inestone8 and %ater a sli#y stone.

s prophyla<is against tartari! diseases, the physi!ian #ust pay spe!ial attention to the preparation of the food. I, p. 1:8 The nutrition of #anRfood and drin*Rshould be espe!ially!leansed fro# tartar. ?urther#ore, the spe!ifi!ally guilty tartars in the different regions should

be as!ertained and e<!luded fro# the food. ?or instan!e, the Pehlhei#er %ine %ould !ause the body a large a#ount of tartari! separation %or* but not the Ae!*ar %ine, therefore thePehlhei#er should be forbidden.

?ro# #any obser$ations I %ould li*e to #ention one as far as I a# !on!erned, I ha$e ne$erseen a !ountry %here there are so fe% tartari! diseases as in &eltlin& a $alley in the Italian lpsOsouth of 3a*e Co#o8 %here there are less than in Ger#any or Italy, ?ran!e or the /!!identor,the European /rient. In this !ountry, eltlin, the inhabitants ha$e neither podagra nor !oli-!a#,



!ontra!tura# nor !al!ulu#. It is su!h a healthy !ountry that e$en that %hi!h gro%s there ishealthy, and not #any better, healthier lo!ations !ould be found in all #y far tra$els. I, p. 48

?or the !ure of so#e diseases 2ara!elsus suggests spe!ial dietary pres!riptions. ?irst for the bladder and *idney stones I, p. :;98 the follo%ing are forbidden #il* produ!ts, !heese, al*a-hne or lead-!ontaining %aters, rain %ater, sour sea sla!*s, sour "ine, #eat !rabs and fish.ubstan!es of ri!h #ineral and purin !ontent are intuiti$ely forbidden to pre$ent phosphati! and

uri! a!id stone for#ations. "hen pains are present poppy seed #orphine8 is re!o##ended to

render the bladder insensiti$e.8 /n the other hand, there are the follo%ing re#edies I, p. 1)(8,%hi!h redu!e and do not trans#ute or pre!ipitate, for pre$ention of bladder and gall stonesThere is nothing so #u!h to re!o##end as butter and oli$es. 'eartburn II, p. )98 deri$esfro# %ine, salty #eat and $enison. These should be a$oidedO as a re#edy he suggests #u!h#il*, t. Lohn&s bread, !hal* al*ali08, sealing earth #agnesiu#8, ar#eni! !lay and o!ean!hal*. Then he pres!ribes daily $ita#in doses through !onsu#ption of #elon 5ui!e and fruit,!ontinuous usage of %in!h should pre$ent the for#ation of stones in the intestinal tra!t.

In a !onsiliu#, II, p. ;7(8 2ara!elsus re!o##ends against 2odagra and i##inent stro*e besides the #edi!al !ures of the %atering pla!es su!h as 2feffers and "ildbad Gastein8 as the

follo%ing %hen you are ta*ing the baths you should be abste#ious %ith food and drin*, and%ith %o#en you should ha$e little or no inter!ourse. ?ish is forbiddenRbut %hen fried it doesthe least da#ageO no tough, hard #eat and nothing fro# the pig is per#itted. s drin*, an old,#ild, !lear red %ine %ould ser$e bestO beer should be ta*en only rarely and then it should not be!onsu#ed %ithout nut#eg and fer#ented bread. s prophyla<is, he re!o##ends II, p. ;:78this is #y ad$i!e ho% you !an prote!t yoursel$es, na#ely, four things should you a$oidR strong s#elling %ineRlas!i$ious foodRangerR%o#enO and the #ore abste#ious you shall li$e inthese things the better. ?or pre$ention against stro*e of brain or spinal !ord, dizziness and

pleurisy, he 1 ad$ises that the follo%ing foods should be a$oided as #u!h as possible spi!es,strong %ine, herb %ine, garli!, #ustard, $inegar O and fish, espe!ially the fried foods. bstentionis good, but one #ust not suffer hunger or thirst and should sti!* to one&s daily habits at all hours.

This is not a re!o##endation for fastingR!ures.In a !ertain aetiologi!al !ontrast to the tartari! diseases he puts the infe!tious diseases. In

2ara!elsus& ti#e an atta!* of disease through infe!tion by ba!illi %as not yet *no%nO in hisastrologi!al *ind of !on!eption he tra!es the origin of infe!tious diseases ba!* to the effe!t of thestars. These !onsu#e the patient I through their fires, they !ause the body to dry up and %itherOtherefore, the ar!anu# in these patients is #oist food and !onsu#ption of large a#ounts of#oisture. ?or the patient si!* %ith the plague, he says SI, p. 7(98 that one should not gi$e the#any #eat, eggs, fish and nothing fried. ?or drin*, they should be gi$en only soup of %ater or

barley sau!e %ith rose $inegar. The #ost

26CE3@& >IET6F 6EGI=E )

useful drin* is barley %ater #ost of this is the original tea!hingof 'ippo!rates8.

CONCLUSION In the#sel$es, the state#ents of 2ara!elsus about diet are not unifor# but one !an noti!e

e$ery%here in the# the thought that !o#bines the#O their !he#i!al effe!t. E$ery%here in his%ritings it !an be per!ei$ed ho% he %ould li*e to disse!t e$erything into the finest parti!lesato#s8 and find an interpretationO it see#s as if he %ould li*e a penetrating po%er to enable hi#to loo* into things #i!ros!opi!ally. The lay#an only sees the surfa!eO the physi!ian #ust be able

to $isualize the inside and the hidden fa!ts %hi!h !o#bine to for# the %hole, regardless of%hether it is a pie!e of %ood or bone. =ar$elous are his ideas about the !he#i!al rea!tions andhis passionate lo$e for all !he#i!al o!!urren!es %hi!h he applied to the rea!tions of the body



long before his ti#e. 2ara!elsus see*s to de$elop e$erything fro# its origin. In that he al%aysobser$es three things the hea$en, the earth and the #i!ro!os#O it is si#ilar %ith healing. =an!an only be !o#prehended through a #a!ro!os#O not through hi#self alone. /nly the *no%ledgeabout this har#ony perfe!ts the physi!ian.

This short !ondensation does not ta*e a !riti!al stand in the histori!al sense to%ards thestate#ents of 2ara!elsus as #easured against the *no%ledge of his ti#e. It #erely see*s to sho%

ho% sti#ulating his %ritings are and the %ealth of ideas %hi!h shines through e$ery%here, ho%intense his urge to find !ausal !onne!tions or at least to inti#ate the# in his passionate %ay and

bring the# in a!!ordan!e %ith the eternal la%s in nature outside of the body and the sa#e la%sruling inside the #i!ro!os#.

C-APT1R .III

$ifferent Authors% Cancer Therapies &y $iet 0 A

Survey

P. '. @E6 %rote that %e #ust distinguish sharply bet%een nutritional prophyla<is and !an!ertherapy by diet.J >r. auer ta*es a stri!tly negati$e attitude to the +uestion of dietary therapy in!an!er, ?or this reason, he lists the dietary regi#es of a nu#ber of authors 18 ?is!her-"asels19-19)8 re!o##ended the a$oidan!e of o$ereating, nutrition poor in sugar, %ater and salt,

poor in $ita#in , !holesterol, al*aline, and a higher a!idity to be rea!hed by inta*e of a!idfoods and addition of a!ids. ee >r. Puhl.8

(8 uler 197-19;18 re!o##ended a non-sparing diet, ri!h in salt and spi!es, ra% #eatse$eral ti#es %ee*ly, 5ui!es of $egetables and fruits and oils to repla!e ani#al fats.

8 ?reund and Pa#iner, %hose dietary e<peri#ents %ere highly regarded for a long ti#e,suggested repla!e#ent of ani#al fats by $egetable oils to a$oid gro%th of the si!* ba!teriu# !oliand pre$ent the for#ation of nor#al fatty a!ids. Carbohydrates %ere to be redu!ed and theintestines %ere to be !leansed by #eans of physi!s and #edi!ation. ?reund and Pa#iner %ere thefirst to list per#itted and prohibited foods 191(-19()8.

;8 Pretz, ienna 1998 leaned !losely on the re!o##endations of ?reund for thei#pro$e#ent of the general !ondition of the !an!erous organis#.

)8 ruenings, ?ran*furt a=ain 19&s8 re!o##ended a diet poor in !arbohydrates and ri!hin proteins, aided by insulinO he belie$ed in i#pro$e#ent by an a!idifying effe!t.

;CP. '. auer, Das @rebsproblem The Can!er 2roble#8, pringer erlag, erlin, 19;9, p. 4).

48 E. alzborn, ienna 19;8 ad$o!ated a dietary regi#e for inoperable !an!er patients

%hi!h !onsisted of little protein and fat, fe% $ita#ins, #inerals and foods %ith a redu!ed a#ountof !arbohydrates be!ause of fer#entation and gas produ!tion.

78 Ingebos 19;(8 re!o##ended a regi#e based on the ideas of =ason in 3oe%enO theregi#e a$oided fats and foods ri!h in fats, espe!ially those ri!h in !holesterol, and also a$oidingartifi!ially !olored foods and drin*s. 'e prohibited salt and #eat and fishRfrozen, s#o*ed orsterilized. Easily digestible foods %ere per#itted lean fish grilled or broiled, !hopped lean #eat,

brains, and thy#us %hi!h !ould be !oo*ed. ll $egetables should be ser$ed ra% or !oo*ed in%aterO $egetable soup and oat#eal, $egetable oils, fruit and potatoes %ere part of the regi#eO

bread %as per#itted. l!oholi! be$erages, pepper, #ustard and papri*a %ere forbidden, as %ass#o*ing.

auer presents a su##ary of ans%ers to +uestionnaires sub#itted to ; physi!ians by the

Monatschrift fuer @rebsbekaemp9fung.CC "ith the e<!eption of 2rofessor >en* of ienna, all the physi!ians sho%ed a negati$e attitude to dietary therapy in their ans%ers. o#e loo*ed upon diet#ore as a #eans of pre$enting !auses of !an!er than a #eans of treating !an!er.



In his boo*, #ancer and Diet, >r. ?rederi!* 3. 'off#an rea!hed the !on!lusion that !an!er isnot lo!al in its originO treat#ent should, therefore, not be li#ited to the lo!al lesions. deranged #etabolis# is the result of dietary and nutritional disorders #anifesting the#sel$es in$arious %ays, not diffi!ult of as!ertain#ent by #ode# #ethods of e<a!t s!ientifi! deter#ination,!hiefly gastri! and blood analysis, or other pre!ise #ethods of indi!ating blood disorders.

I a# absolutely !on$in!ed that the underlying !ause of !an!er is to be found in an e<!essi$e

inta*e of foods of a high organi! or #ineral !ontent, or generally of an al*aline base insteadof a!id In brief, the tea!hing of #ode#-day nutritional s!ien!eshould be the urgen!y of #oderation in all thingsR#oderation in food inta*e, parti!ularly as tohighly-spi!ed foods, #oderation in bodily fluids, in!luding al!oholi! be$erages, !offee and tea, as%ell as #oderation in the use of toba!!o. I##oderation in any one parti!ular dire!tion fa$ors thelo!al de$elop#ent of #alignant

Y Monatschrift fuer @rebsbekaempfung, ol. 9, 194, p. ()7

gro%ths. ... I !onsider #y o%n duty dis!harged in presenting the fa!ts as I ha$e found the#,

%hi!h lead to the !on!lusion that o$ernutrition is !o##on in the !ase of !an!er patients to are#ar*able- and e<!eptional degree, and that o$erabundant food !onsu#ption un+uestionably isthe underlying !ause of the root !ondition of !an!er in #ode# life.;)

In Dietotherapy #linical $pplication of Modern "utrition, !ar!ino#a of the sto#a!h isdes!ribed as essentially a surgi!al proble#. post-operati$e diet is re+uired only after subtotal ortotal gastre!to#y. /n!e the patient has sur$i$ed the operation and the !on$ales!en!e hasfollo%ed, the diet is $ery liberal and pra!ti!ally without restrictions. 2atients %ho ha$e suffered

partial rese!tions of the sto#a!h !an #anage pra!ti!ally the sa#e diet as nor#al persons.;4

Purt te# and 6obert "illhei# %rote, In regard to the relation bet%een food +uantity andtu#or gro%th, the pre$ailing #a5ority of authors ha$e e<pressed the opinion that food restri!tionis follo%ed by a depression of neoplasti! gro%th.;7

3i*e ?. 3. 'off#an 1978, E. ?riedberger 19(48, . Tan-nenbau# 19;-;(8, ". Caspar19:8 and others e<pressed the sa#e opinion and ad$o!ate #oderation in food. real therapy isnowhere to be found, although so#e authors are not as pessi#isti! as others.

The different dietary propositions #ade at the International Congress for Totality Treat#entsof Tu#ors in 19)( %ere not put into pra!ti!e, although #any of the propositions had the !orre!tapproa!h.It is not ne!essary here to pay attention to the #any proposals for applying one or #ore $ita#ins,or enzy#es or those #i<ed %ith #inerals. It %ould be a pri#iti$e !on!ept to propose that thead#inistration of one or another enzy#e, $ita#in or #ineral or their !o#position %ould !hangeor !ountera!t the enzy#ati! disturban!e or intra!ellular nature. Aearly 1 years ago, /tto oel*er %rote The degree to %hi!h a disease is open to

therapeuti! atta!* is in$ersely related

;) ?rederi!* 3. 'off#an,3.3.>.,Can!er and Diet, "illia#s and "il*ins Co., alti#ore, 197.;4 Dietotherapy #linical $pplication of Modern "utrition, edited by =i!hael G "ohl, =.>., ". .

aunders, 2hiladelphia, 19;4, p. )7 and ff.Purt te# and 6obert "illhei#, The 4iochemistry of Malignant Tumors, 6eferen!e 2iess, roo*lyn,

19;, p. 91.

to the nu#ber of re#edies that %e possess.;: Ao%here is this#ore true than in !an!er, for %hi!h treat#ents ha$e been ad$an!ed by the thousands. The olderones in!luded !rab or !rab soup, no doubt an early appli!ation of the #ista*en theory that li*e!ures li*eO purgationO yeast treat#entO different dietary regi#esO hypere#ia and its oppositeO

bloodlettingO sal$esRfirst bla!* and later, if this pro$ed ineffe!tual, red onesO !austi! pastesO hotiron-burningsO pipe !layO blood-!leansing teasO sil$er and goldO #er!uryO !opperO phosphorusOarseni!Re<ternally and internallyO nar!oti!sO !o#pressionsO .!oldsRlong before the re!ent $entureinto !he#otherapyO a!idsO al*alisO diaphoresisO $egetable produ!ts of all sorts, in!luding $iolet



lea$es and toadsO auto-$a!!ine lu#en-thal8O polysa!!haride 'att8O i#planting of erysipelasstrepto!o!!i, et!.

The #ode# !an!er re#edies in!lude surgery, N-ray treat#entO radiu#O ionized #inerals gold, phosphorus, iodine, !obalt8O !o#binations of $ita#insO hor#onesO 6e$i!i&s lodoa!etateOPrebiozin, and the ne%est proposal of !reation of !an!er fo!!i on the s*in as !an!er of oneorgan shields other organs to a !onsiderable e<tent.;9

s !an!er author "illia# '. "oglo# %rites, If %e ha$e no !ure of !an!er today, surely it isnot fro# la!* of trying.;:

To present a histori!al sur$ey of all the therapeuti! atte#pts to influen!e the !an!er gro%th, orat least to alle$iate pain, %ould be e<tre#ely diffi!ult. !o#plete sur$ey #ay run into thousandsof enu#erations, as old popular !an!er re#edies, based on natural obser$ations, #ay be found inal#ost all !ountries of the %orld. E$en in #odern s!ientifi! therapy, al#ost all atte#pts ha$efailed, %hether in the fields of ba!teriology, i##unology or bio!he#istry. In su##arizing therelations bet%een tu#ors and enzy#es, Purt tern and 6obert "illhei# said that of thetherapeuti!al uses of enzy#es in tu#or pathology it %ould be an e<tre#ely pri#iti$e !on!ept ifad#inistration of one enzy#e or the other %ere to be proposed as an effe!ti$e #eans of!ountera!ting an enzy#ati! disturban!e of ne!essarily intra!ellular nature. s a #atter of fa!t, noinstan!e is *no%n in general pathology, %ith the e<!eption of gross intestinal defi!ien!ies ofenzy#es, in %hi!h

;: Quoted by "illia# '. "oglo#, $pproach to Tumor #hemotherapy, 19;7, p. 1.- '. 2eller, =.>. #ancer in Man, 19)(, p. ;::.

an enzy#e therapy has pro$en useful pepsin and trypsin8 ).2rofessor 3eupold had so#e results by !hanging the blood-!he#is#usRthe !holesterin-sugar-phosphati! syste#.J1

?eller brought up a theory for !an!er !ure in his boo* by saying, !an!er of one organ shieldsother organs to a !onsiderable e<tent. !ured !an!er lea$es an in!reased resistan!e to the de$el-op#ent of another pri#ary tu#or in so#e other part of the body, lthough the nature of thisresistan!e is un*no%n, its utilization for !an!er !ontrol is possible. . . . The pri#ary tu#or is alo!al #anifestation of a general disposition to !an!er.)( 2eller arri$ed at this notion fro# so#eobser$ations in tuber!ulosis. It %as !on!luded by se$eral authors that tuber!ulosis of the s*inlupus8 prote!ts the other organs, espe!ially the lungs, against the tuber!ulosis infe!tion.

fe% %ords #ay be added to the abo$e-#entioned !ontradi!tions in !an!er treat#ents!ientists ha$e s*irted the nu!leus of the proble# throughout the !enturies as des!ribed in thehistory of #edi!ine. s soon as one of Aature&s se!rets is un!o$ered, apprehension and s*epti!is#appear.

The history of #edi!ine is filled %ith tragi! errors %hi!h allo%ed su!h a long ti#e to elapse bet%een the ti#e of dis!o$ery of a basi! prin!iple and the a!tual #edi!al appli!ation of the

dis!o$ery for the good of #an*ind. To +uote fro# a re!ent paper by 'a##et, Ao%here today isthis delay #ore unhappily e$ident than in the field of !an!er resear!h. The a!!u#ulated data of6ous, hope, Coley, ittner, trong, nder$ont, Green, Greene, "illia#s, Taylor, ?urth,T%o#bly, Co%dry, >iller, a%den, 2irie, tanley, "y!*off, Punitz, and others indi!ate beyond

per-ad$enture the path for getting at so#ething of pra!ti!al benefit to the !an!er patient of thefuture other than surgery and ra-

) Purt tern and 6obert "illhei#, The 4iochemistry of Malignant Tumors.)1 2rof. Ernst 3eupold, The 'ignificance of 4lood #hemistry in &egard to tumor Growth and Tumor

Destruction, Georg Thie#e erlag, tuttgart, p. 1;.)( . 2eller, =.>., #ancer in Man, 19)(, International @ni$ersities 2ress, Ae% For*, p. ;::.) 'cience, Aol. 1, Ao. (4:), 19;4, p. 71;.

C-APT1R I=



deterioration of the li$er !annot be dete!ted before the great fun!tional reser$es ha$e been!onsu#ed. In addition, the fi$er has great !apa!ity to regenerate, therefore, a partial destru!tion#ay be restored if lie deterioration is not e<tensi$e and rapid.

The fi$er has #anifold fun!tions, and #ost of the# are !losely asso!iated %ith the fun!tion ofother organs. /ne is for!ed, therefore, to ta*e se$eral fun!tional tests to #easure the fun!tionaldegree of the fi$er. The !onstant up%ard and do%n%ard trend of this large dyna#i! organ #a*es

it ne!essary to repeat the tests before a #ore positi$e state#ent !an be for#ed. The i#portan!e ofthe li$er %ill be best des!ribed by !o#parison %ith the !hlorophyll !ontained in the !ells of lea$es

R#aintaining #etabolis# and the life of the plant."hen se$eral authors e<a#ined the fun!tion of the li$er of ) patients %ith $arious types of

!an!er of the gastro-intestinal tra!t, they found a pronoun!ed hepati! dysfun!tion. )) fter re-#o$al of the tu#ors, the li$er re!o$ered to a !ertain degree, for so#e ti#e. Thus, the !hangessho%ed that the deterioration !an

); ". . >. nderson, Pathology. 19;:, p :41.))ee bels, 6e*ers, et al, nnal of Internal =edi!ine, 14, ((1 19;(8.

be re$ersed. =ay I anti!ipate that the treat#ent des!ribed here does the sa#e The absorption of

the tumor mass and glands and the restoration of the function of the liver.

Lesse Greenstein stated that, there see#s to be little doubt that hepati! insuffi!ien!y is a!on!o#itant pheno#enon %ith !an!er and, as the authors e#phasize, su!h da#aged li$ers i#posean additional hazard to those nor#ally a!!o#panying operati$e pro!edures.):

In so#e bio!he#istry boo*s on !an!er, the li$er deterioration in !an!er is di$ided into threestages The first stage represents the ti#e of the de$elop#ent and the appearan!e of !an!er.>uring that ti#e the dysfun!tion of the li$er is, as #any authors assu#e, present but undete!table

by #eans of tests or palpation. I belie$e, ho%e$er, that the fi$er has lost P and P-group #ineralsso that the o<idizing enzy#es !an no longer be reo<idized in suffi!ient +uantities to !ontrol all!ell gro%th.

>uring the second stage, the tu#or gro%s and so#e #etastases appear in glands. /ne !an palpate an enlarged li$er hypertrophy8 and find so#e ede#a in the organs. t that ti#e, %eassu#e that the a!ti$ity of the !an!er has in!reased %hile the defense and the healing po%er ofthe body has de!reased !orrespondingly.

In the third stage, in %hi!h the !an!er has gained supre#a!y, rapid poisoning and destru!tion ofessential organs set in %ith later dissolution of these organs, in!luding the li$er %hi!h !an nolonger #aintain its substan!e and fun!tions.

In the first stage, the tu#or protein %ould see# to be supported by nor#al foodO in the se!ondstage, #ost probably, the protein is supported to a greater or lesser degree by the #us!le tissue.t this ti#e there is !onsiderable hyperlipe#ia present, %hi!h re#ains until the reser$es of the

body&s lipids are !onsu#ed.

In the third ter#inal stage, there is an a!ute, rapid loss of #us!le and li$er substan!e, sin!e$ery little defense or resistan!e is left. 'o% the tu#or produ!es su!h a !ondition is un*no%n.Lesse Greenstein assu#es the produ!tion by the tu#or of a !ir!ulating to<in, %hi!h a!!elerates the!atabolis# of the body tissues. 6udolf Peller thin*s that the progressi$e loss of potassiu# andthe #inerals of the potassiu# group lo%er the ele!tri!al potentials

)4 Lesse Greenstein, 4iochemistry of #ancer, 19);, p. )9. )7 Ibid., p. )1.

and the defense of the !ytoplas# in #us!le and li$er !ells. The sti#ulation of the $is!eralner$ous syste# by the loss of potassiu# and the in!rease in tu#or poisons also see#s to be a!ontributing fa!tor to this deleterious effe!t. high per!entage Rabout 9 per !entRof our

patients are ter#inal !ases. These patients !annot %ait for treat#ent to be de$eloped. This %asthe reason that for!ed #e to bring #y treat#ent to its highest effi!a!y in e$ery respe!t.

The first physi!ian %ho dre% attention to the !o#bination of !an!er and the fi$er or gallbladdersyste# probably %as ?reri!hs, in 1:41. 3ater, #any physi!ians agreed %ith hi#, su!h as Men*er,



?uetterer, iegert, Parnot, lond, et!. The e<isten!e of the relationship %as denied by Prehl,'eller and others. The pathologists %ere also of different opinions s!hoff and a!*#eisterde!ided that the disease of the fi$er and bile syste# %ere a!!idental findings. 3ubars!h andothers opposed this $ie%. Aeither !lini!ians nor pathologists nor biologists %ere able to sol$e the proble# which was the

first or the !ausati$e fa!tor. The great diffi!ulty is that %e !annot deter#ine %hen the pathology

of the li$er or bile syste# starts.The ne%er labeled e<a#ination %ith C1; gly!ine by Aorbert E. and >. =. Greenberg): pro$ed

that the li$er and plas#a of tu#or-bearing ani#als ha$e an in!reased protein #etabolis#.The sa#e effe!t o!!urs also in pregnan!y #easured by gly!ine C1; and 2( in li$ers of tu#or-

bearing ani#als8 %hi!h refle!ts a +ui!*er gro%th so#e%here else in the body. This #eans thatthis !ondition is not spe!ifi! for !an!er and is not !aused by spe!ifi! to<ins.

It is i#portant to re!ognize that, in our body, all the inner#ost #etaboli! pro!esses %or*together, are dependent upon one another, and %ill be deranged %ith ea!h other in diseases. .piegel#an said in an arti!le as %ell as at the Third International Congress of io!he#istry in19)) p. 1:)8 ?or o$er 4 years there ha$e e<isted in the #i!ro-biologi!al literature a series ofobser$ations subsu#ed under the title of &enzy#ati! adaptation,& in %hi!h a parti!ular !o#pound

apparently e$o*es a %ell-defined !hange in the enzy#e patterns of !ells, gro%n in its presen!e.The last de!ade has %itnessed a rene%ed interest in these analogous

6eported in #ancer, ; :, 19)1.

findings. There, geneti! and enzy#ologi!al aspe!ts ha$e been ree<a#ined %ith the aid of #orerigorous te!hni+ues and #ethodology than those that %ere a$ailable to the earlier %or*ers.These ne%er pro!edures #ade it possible to sho% in a nu#ber of !ases that the pheno#enon ofenzy#ati! adaptation possessed the follo%ing i#portant features a8 the !hanged enzy#ati!a!ti$ity %as not due to the sele!tion of pre-e<istent #utant types but rather to an in!ludedenzy#ati! #odifi!ation against a !onstant geneti! ba!*groundO b8 the obser$ed !hange in

enzy#ati! a!ti$ity !ould be as!ribed to the appearan!e of a!ti$e apoenzy#e rather than to thea!!u#ulation of !o-fa!tors or inter#ediates, uni+ue to the #etabolis# of the indu!ingsubstrate. ... It %as ne!essary, therefore, to re$ise su!h state#ents as genes !ontrol potentiality ofenzy#e synthesis.

The proble# of the li$er %as, and still is, partly #isunderstood and partly negle!ted. The#etabolis# and its !on!entration in the li$er should be put in the foreground, not the !an!er as asy#pto#. There, the out!o#e of the !an!er is deter#ined as the !lini!al fa$orable results,failures and autopsies !learly de#onstrate. There, the senten!e %ill be passedR%hether thetu#ors !an be *illed, dissol$ed, absorbed, eli#inated and, finally, %hether the body !an berestored.

The progress of the disease depends upon the possibility of %hether and to %hat e<tent the

li$er !an be restored, of !ourse, unless there are so#e !o#pli!ations and destru!tions in the $italorgans.

The treat#ent of the li$er is generally #ore sy#pto#ati!, but not %ith the des!ribed treat#ent.It has be!o#e in!reasingly e$ident that li$er !irrhosis is inti#ately asso!iated %ith pri#ary

li$er !an!er, and that en$iron#ental fa!tors play an i#portant part in the pathogenesis of bothdiseases, er#an stated. Pasper lond said In the li$er %e ha$e tried to sho% that !irrhosis ofthe li$er is not a disease sui generis, but only a sign of a disorder of #etabolis# %hi!h !auses a!hain of e$ents leading to #any !onditions %hi!h the #edi!al generation of today !onsiders to

be diseases sui generis. The %hole syndro#e of #etaboli! disorders %hi!h %e !all oesopha-.gitis, gastritis, duodenitis, gastri! and duodenal ul!er, !hole!ystitis, !holangitis, pan!reatitis,

pro!titis, and others are !onsidered only stages of a dyna#i! pro!ess, starting %ith li$er failureand portal hypertension, and resulting in !irrhosis of the li$er tissue and in !an!er. Can!er is a#utation of so#ati! tissues !aused by !hroni! da#age of the li$er. The stru!tural !hanges of theso#ati! tissues are the result, not the !ause, of the #etaboli! disorders.):



lond has studied this proble# sin!e 19(: to e<plain !an!er physiology and pathology through bile produ!tion, absorption, se!retion, and storage as a disorder of the !ooperati$e organs. 'e!a#e to the !on!lusion that %e !an sol$e #ost of the in$ol$ed proble#s if %e study the

physiology of man as a whole, rather than !ells, stru!tures, or single organs. In that respe!t, hegoes !ontrary to #ost !an!er authors %ho e#phasize a dire!t study of the site of #alignan!yitself, as, for e<a#ple, Lesse Green-stein.:

lond did not try to de$elop a therapy on that basis but too* his $ie%point fro# statisti!s and!a#e to the !on!lusion that 9:Z of all !an!ers of the internal organs su!!u#b not to the !an!er

but to the li$er disorder.41 'e does not e$en #a*e any suggestion to help the li$er in the fight todefend or #aintain the body. lond&s !on!eption see#s to be right and reasonable. 'isenu#eration of the li$er syndro#es, ho%e$er, see#s to be too strongly pronoun!ed. I find the##u!h less a!!entuated e$en in the #ore ad$an!ed !ases. Aot all !an!er !ases ha$e !irrhosis,although the #a5ority sho% a pre!irrhoti! stage of li$er hypertrophy.

>r. George =edes reported to the #eeting of the #eri!an Che#i!al o!iety in 19)) that!hanges in the !he#istry of the li$ing !ells all o$er the body ha$e been deter#ined in rats %henli$er-!an!er stri*es. 'e suggested that the dis!o$ery %ill shed ne% light on the %ay !an!er for#sin the body and the %ay it #ay be pre$ented. >r. =edes !on!entrated on the synthesis and

utilization of fats by li$ing and gro%ing tissues under $arious dietary !onditions. !eti! a!id,%hi!h is *no%n to be for#ed fro# both fats and !arbohydrates, has been used to represent foods.Earlier, >r. =edes found that, %hile all tissues !ould use both of these substan!es for the

produ!tion of fats, there %as a differen!e in nor#al tissue and tu#ors. The nor#al li$er of the ratutilized a!eti! a!id to synthesize and o<idize it to !arbon

) Pasper lond, The iver and #ancer, 19)), p. 14. no Lesse Greenstein, 4iochemistry of

#ancer, p. )9:. 41 Pasper lond, The iner and #ancer, p. 197.

dio<ide and %ater at se$eral ti#es the rate at %hi!h the tu#or did, %hereas the re$erse o!!urred%ith glu!ose in nor#al and tu#or-bearing rats.

In 19(4, the =ayo Clini! reported the $ery lo% in!iden!e in li$er !ar!ino#a of .: per !ent.That in!reased till 19;9. The highest in!iden!e %as reported during 19;: to 19)(. It is generallya!!epted that the rising in!iden!e of pri#ary !ar!ino#a of the li$er #ay be due to an in!reasingin!iden!e of li$er diseases and !irrhosis in general. These are regarded as !auses of theneoplasti! transfor#ation. The latest statisti!s of the in!iden!e of pri#ary !ar!ino#a of the li$ersho% the predo#inan!e of this disease for !ertain ra!ial groups and geographi! areas.

In general, pri#ary !ar!ino#a of the li$er is #u!h #ore !o##on in !olored ra!es than in the%hite ra!e, %hile #alignan!ies in general are less fre+uent in !olored people. The per!entage ofli$er !ar!ino#a to other !ar!ino#as is one to t%o per !ent in Europe and #eri!a %hile Chineseha$e per !entO La$anese, 4.1 per !entO ?ilipinos, ((.( per !entO Lapanese, 7.) per !entO and-outh fri!ans in the Gold =ines, :4.4 per !ent. E%ing and other authors found that pri#aryhepato#as and ) per !ent of pri#ary !holangio#as are asso!iated %ith !irrhosis. The >a#o!less%ord of !irrhosis hangs o$er all !an!er patients %ho ha$e far ad$an!ed #alignan!ies in theirabdo#inal organs. "e *no% that all these organs send their blood through the portal $eins intothe li$er %here tu#or !ells settle $ery fre+uently as soon as the li$er, %or*ing as a filter, has lostits defense po%er.

Terato#as of the li$er are e<tre#ely rare. ?or li$er fun!tion tests, see spe!ial te<tboo*s. bels,6e*ers and others reported a-high in!iden!e of hepati! dysfun!tion in patients %ith !an!er of theintestinal tra!t.

In his boo*, pellberg says that 2ri#ary !an!er of the li$er o!!urs so #u!h #ore fre+uently inthe !irrhoti! li$er as !o#pared %ith the nor#al li$er that !irrhosis has been referred to as a pre-

!an!erous lesion.

(

nd, he also says, There is no dispute that an ade+uate diet is essential in thetreat#ent of li$er diseases.4e$eral authors ha$e obser$ed that if the surgeon re#o$es a tu#or of one of the abdo#inal



the li$er is i#paired. The reason has not yet been found. The ratio of Salbu#inglobulinU

is therefore lo%ered in the li$er diseases and used for one of the tests. "eoplasia bout 1( #alignant tu#ors arise pri#arily in the li$er. =ost #alignan!ies are

#etastati! in origin and are deri$ed fro# the intestinal organs.

Pathology0Liver?ifty patients %ith $arious types of !an!er of the general intestinal tra!t presented pronoun!edhepati! dysfun!tions.4: fter re#o$al of the tu#ors the li$er re!o$ered to a !ertain degree forso#e ti#e, but the !hanges sho%ed that the deterioration is re$ersible. =ay I anti!ipate here thatthe des!ribed treat#ent does the sa#e re#o$al of the tu#or-#ass, glands, et!. and ano$er!o#ing of the dysfun!tion of the li$er. !!ording to Green-stein, There see#s to be littledoubt that hepati! insuffi!ien!y is a !on!o#itant pheno#enon %ith !an!er and, as the authorse#phasize, su!h da#aged li$ers i#pose an additional hazard to those nor#ally a!!o#panyingoperati$e pro!edures.49

>uring the first stageE de$elop#ent and appearan!e of the diseaseRthe li$er dysfun!tion isundete!table. >uring the second stageRtu#or gro%th and so#e #etastases in glandsRone finds

the li$er #ostly hypertrophi! and, as %e see in so#e !ases, also hypertrophy or ede#a of otherorgans. In the third stageE an al#ost entire ruling autono#y8 of the !an!er-%ith rapid poisoning,destru!tion and later dissolution of the organs, in!luding the li$er, %hi!h !an no longer #aintainits substan!e and fun!tions.

47 Lensen, Modern #oncepts in Medicine, #. . =osby Co., 19), p. 17;. 4: gee bels, 6e*ers, et.al, $nnual of <nternal Medicine, 14((1, 19;(. 49 Lesse Greensfein, 4iochemistry of #ancer, p. )9.

In the first stage the tu#or-protein %ould see# to be supported by the foodRin the second stage#ost probably a part of the protein is supported by the #us!le tissue and at that ti#e there is!onsiderable hyperlipe#ia present %hi!h stays there till the reser$es of the body&s lipids are

!onsu#ed.In the third or ter#inal8 stage there is an a!ute loss of #us!le and li$er substan!e and allresistan!e is lost. 'o% the tu#or produ!es su!h a !ondition is un*no%n. Greenstein assu#es the

produ!tion by the tu#or of a !ir!ulating to<in %hi!h a!!elerates the !atabolis# of the bodytissues&7 6udolf Peller thought that the progressi$e loss of P-and P-group #inerals areresponsible for it by losing the ele!tri!al potentials and defense of #us!le !ytoplas#a. Thesti#ulation of the $is!eral ner$ous syste# by the loss of P and the tu#or poisons see#s also to

be !ontributing to this deleterious effe!t.The ne%er labeled e<a#ination %ith C1; gly!ine by Aorberg and >. =. Greenberg pro$ed that

the li$er and plas#a of tu#or-bearing ani#als ha$e an in!reased protein #etabolis#.71

The sa#e effe!t also o!!urs in pregnan!y #easured by gly!ine C1; and 2( as in the li$er of

tu#or-bearing ani#als8 refle!ting a +ui!*er gro%th so#e%here else in the body. That #eans thatthis pro!ess is not spe!ifi! for !an!er and is not !aused by spe!ifi! to<ins.

The benefi!ial influen!e of large a#ounts of !arbohydrates in the diet has been re!ognized.esides the prote!ti$e a!tion of gly!ogen upon the li$er !ell, further benefit is deri$ed fro# !ar-

bohydrate by $irtue of its protein-sparing a!tion. The prote!ti$e $alue of !arbohydrate appears to be t%i!e that of protein %hen suffi!ient protein is already present in the diet to pro$ide plenty andne!essary a#ino a!ids for reparati$e purposes. n iso!alori! a#ount of !arbohydrate !annot besubstituted for proteins %ithout deterioration of the !lini!al and bio!he#i!al state. ?ifty-eightgra#s #ay be spared by !on$ersion to !arbohydrate %hen 1 gra#s of protein are fed if the!arbohydrate inta*e is enough to satisfy the i##ediate need for sugar. Ae$ertheless, the additionalre+uir#ent of high biologi! $alue protein in patients %ith li$er disease are not *no%n, the

indi!ations are that there is a great protein %astage. nore<ia, hypoproteine#ia, and loss of%eight



7 Ibid., p)1.ee report by Aorberg and Greenberg, #ancer, ;:, 19)1.

are positi$e e$iden!e of protein depletion. @n!o#pensated li$er !ell protein !atabolis# alsoi#plies rapid loss of enzy#e proteins of all types. 2rotein repletion #ay help, therefore, inrestoring the ne!essary enzy#es. There is little ris* of protein surfeit e$en if the patient

!onsu#es protein beyond satiety. This reassuran!e is %el!o#e sin!e there is so#e relu!tan!e inso#e +uarters to o$erload the insuffi!ient li$er. >o!* has de#onstrated that the li$er differsfro# the *idney in the !apa!ity to handle protein e<!ess. The hepati! artery !ir!ulation !an ta*eup the in!reased de#and for o<ygen %hen the protein !ontent of the diet is in!reased to 7; per!ent.

dietary for#ula %hi!h patients a!!ept e$en %ith #ar*ed anore<ia !onsists of ) to )gra#s of !arbohydrate, 1 to 1( gra#s of protein, and ) to : gra#s of fat. This !o#positionof diet is re!o##ended by nell, tare and Thorn, 2ate*, 2ate* and 2ost, ?le#ing and nellOIngelfinger and 'olt follo% this general for#ula %ith #inor $ariations. =orrison pres!ribed a#a<i#u# protein regi#en %hi!h !o#prises a daily diet of () to ; !alories %ith ( to gra#s of protein, to ) gra#s of !arbohydrates and ) to 1 gra#s of fat. Good#an and

Gar$in su!!eeded in ad#inistering a diet %ith a !alori! $alue of ) !alories deri$ed fro# 1)to () gra#s of protein, 4 to : gra#s of !arbohydrate and 1) to ( gra#s of fat to 1:!ases %ith a!ute hepatitis. 'ourly feedings supple#ented three regular #eals. n al#ostele!tri! response in the patients& physi!al and #ental appearan!e %as noted. >iets planned ine<!ess of these a#ounts are not li*ely to be !onsu#ed in their entirety. It is a better poli!y tooffer a diet %hi!h is a!!eptable regularly and !onsistently. The #a5or proble# is not to pres!ribea diet of a, parti!ular !o#position but to insure the ingestion of a #a<i#al a#ount of nutritiousfood. =issing a #eal is a serious handi!ap in serious li$er trouble. It is best repla!ed pro#ptly

by an intra$enous infusion of glu!ose, se$eral authors thin*.E$ery effort is #ade to #a*e food attra!ti$e. ?at and #eat add to palatability. ?or this reason

'oagland re!ently +uestioned the %isdo# of restri!ting fat. It appears that patients a!tually ha$elittle diffi!ulty in digesting fats in spite of theoreti!al !onsiderations. The fa!t should not be lostfro# sight that the prote!ti$e effe!ts of !holine and #ethionine !an be re$ersed by e<!ess fatsupple#ents. #ple fat, ho%e$er, i#pro$es the effi!ien!y of utilization of !arbohydrate and

protein in the diet. The ob5e!ti$es of i#pro$ed appetite and in!reased !alori! inta*e are readilya!hie$ed by a liberalized #enu. self-sele!ted fare is a step for%ard in this dire!tion. Thedietitian and physi!ian are in$ariably guided by #atters of a$ailable food sto!*s and prin!iples ofdietO the patient *no%s his personal li*es and disli*es better than anyone else. singleunappetizing ite# in a #eal #ay !o#pletely abolish a !apri!ious appetite. ppearan!e or odor#ay de!ide a patient against ta*ing food.

Interest in the diet #ust not lag for a single #ealO the anoreti! patient is only too %illing to s*ip

the ne<t feeding. /n!e a #eal is !onsu#ed, there appears to be no diffi!ulty in handling food-stuffs. @nder !onstant goading, anoreti! patients !onsu#e prodigious #eals regularly, yet sufferno unusual distress. The dietary plan #ust be fle<ible enough, ho%e$er, to per#it $ariations de-

pending on !hanges in the !ondition of the patient. ?or instan!e, %ith in!reasing as!ites, !irrhoti!sfind it diffi!ult to s%allo% large #eals. #all !on!entrated feeds are preferred. 6egular-sized#eals are resu#ed after para!entesis. In the a$erage !ase of li$er disease %here food inta*e is a

proble#, the #id-day repast is usually the best #eal, and the e$ening #eal the %orst. It isad$isable therefore to offer a light supper supple#ented by a generous sna!* later in the e$ening.bdo#inal distention tends to in!rease in the latter part of the afternoon and subside aftersupper. This #ay influen!e daily $ariations in appetite.

It is not a good poli!y to gorge the patient during one #eal only to !ope %ith a disin!lination to

eat se$eral #eals thereafter. 3arge helpings of fatty foods, although they te#porarily i#pro$e theappetite, #ay only pay a li#ited di$idend. ?ats delay gastri! e#ptying. En!roa!h#ent upon thene<t #eal #ay pro$e a net loss in total daily !alori! inta*e.



The protein, fat, and !arbohydrate rations are dis!ussed in detail belo%. The indi!ations and!ontraindi!ations for parenteral glu!ose, plas#a, %hole blood, purified hu#an albu#in, proteinhydrolysates, syntheti! a#ino a!id #i<tures and $ita#ins are re$ie%ed. >iet, ho%e$er, appearedto ha$e no influen!e on li$er tu#ors in rats produ!ed by (-a!etyla#inofluorene. The #anner in%hi!h diet produ!es its pro!ar!inogeni! or anti!ar!inogeni!

- . 3i!hhnaii, =.>. Diseases of the iver, Gallbladder and 4ih Ducts, 3ea ?ebiger, 2hiladelphia,

19) effe!t is un*no%n. Che#i!al differen!es bet%een #ito!hondria of nor#al li$er and #ouse li$erhepato#a has been reported by 'ogeboo# and !hneider.

o#e interesting obser$ations in regard to the influen!e of diet on the de$elop#ent ofspontaneous hepato#as in inbred C': #i!e %ere #ade by Tannenbau# and il$erstone. Thesein$estigators ha$e sho%n that in!rease of fat in the diet fro# t%o per !ent to ( per !entin!reased the rate of hepato#a for#ation fro# 7 per !ent to ) per !ent. 3o% ribofla$in inta*eresulted in a [ de!rease of hepato#a for#ation. This !an be attributed to the lo%ered !alori!inta*e, %hi!h has been sho%n to inhibit gro%th of hepato#as in this spe!ies. It has li*e%ise beensho%n that, !ontrary to the e<perien!es in the indu!ed hepato#as in rats, the spontaneous tu#orsin #i!e are not a!!elerated by a ri!e diet but, on the !ontrary, are a!!elerated by in!reased !asein!ontent. =ethionine has li*e%ise been sho%n to a!!elerate the de$elop#ent of these tu#ors in#i!e. The !on!lusion is dra%n that the sulphur-!ontaining a#ino a!ids, %hi!h are ne!essary fornor#al gro%th, are also ne!essary for gro%th and de$elop#ent of these neoplas#s. gain astartling indi!ation of the si#ilarity bet%een physiologi!al gro%th and neoplasial

Con!erning lipotropi! substan!es, pellberg held that the ob5e!t of the treat#ent is to re#o$ethe fat fro# the li$er and to reinstitute the nor#al hepati! histology and physiology. "ith thetre#endous a#ount of e<peri#ental %or* done on lipotropi! agents, and their effe!ti$eness indietary fatty li$er in ani#als, it is only natural that !lini!ians should turn to these substan!es inthe treat#ent of fatty li$erO ho%e$er, the only type of fatty li$er that !holine Sthe #ost i#portant

of the lipotropi! substan!es8 !an !ure is the one due to !holine defi!ien!y. It is li*ely that atleast so#e of the fatty li$ers in #an are due to !holine defi!ien!y, but in the fatty li$ers of prolonged infe!tion or those due to to<ins, no defi!ien!y of !holine in the diet !an be postulated,and therefore, no benefi!ial effe!t fro# !holine !an be e<pe!ted.&;

"ith regard to diet, pellberg has said that the diet should be high in proteins of good +uality,su!h as #eat and fish. protein inta*e of 1) g#. a day should be ai#ed at. The bul* of the!alories should be pro$ided by !arbohydrates and, therefore,

6uth 3oh#ar#, Pli. "o., 191, Ar. 9. 7; =it!hell . pellberg, Diseases of the iver, p. 9.

this should be !lose to ) g#. a day. The dietary fat should be *ept to a #ini#u#. in!e a

palatable natural diet high in protein !annot be de$ised fat free, at least 7 g#. of fat #ust bein!luded. I !annot see ho% one !an !ondone a high fat diet, espe!ially in the ease of fatty fi$er."hat is the logi! of supplying #ore of the substan!e that %e are trying to re#o$e fro# the fi$er"hen so#e of this e<ogenous fat rea!hes the li$er, it re+uires #ore lipotropi! substan!es and#a*es the ob5e!t of therapy #ore diffi!ult. The diet should be lo% in salt if there is e$iden!e ofede#a or as!ites.7

This is prin!ipally sy#pto#ati! but the diet is of great i#portan!e. It should !onsist entirely of#il* and sugar or other !arbohydrates. ni#al proteins should be redu!ed to a #ini#u#, as theli$er has lost to a great e<tent, if not entirely, its deto<i!ating fun!tion, Intestinal antisepsis by#eans of bis#uth, salol or !alo#el #ay be atte#pted but %ithout #u!h hope of su!!ess. Thefluid inta*e #ust be #aintained at t%o liters or #ore a day. The $o#iting is best treated by

gi$ing fluids half hourly in s#all +uantities but if persistent all foods by #outh should bestopped and intra$enous, re!tal or sub!utaneous ad#inistration of glu!ose saline substituted.. 74 7)

Ibid.



e<!eeded by far the results seen by the appli!ation of the nor#al nutrition plus the usual li$ertherapy.

2ra!ti!al e<perien!e taught us that in #alignan!ies it is ad$isable to apply i##ediately largerdoses of liver FuiceC and in5e!-& tions %ith the !rudest li$er e<tra!t li*e 3illy Ao. 7 !!. !o#-

bined %ith $ita#in 1( 1!! e+ual ) #!g. ita#in 1( see#s to help the body #a*e the !orre!tuse of a#ino a!ids, so that they %ill not be burned unne!essarily but used instead for

!onstru!ti$e purposes. In !an!er, it is one of the essential pro!esses to restore the !onditionsunder %hi!h foodstuffs !an be used in the !orre!t #anner. In the last se$en to ten years %etreated a great nu#ber of patients, #ostly diffi!ult or ter#inal !ases, %ith relati$ely fa$orableresults.

The appli!ation of the li$er therapy in!reased the effe!t of the therapy to a !onsiderable degree.o#e indi!ations %here the therapy %as found fa$orable #ay be #entioned here

a8 Into<i!ation during pregnan!y. b8 Tuber!ulosis of the lungs and other organs.!8 rthritis defor#ans in #ore ad$an!ed stages.d8 =ental diseases and bodily asthenias.e8 pasti! !onditions, espe!ially angina pe!toris.

f8 =alignan!ies.It #ay be added that leu*e#ias and #yelo#as need greater doses of li$er 5ui!eJ and $ita#in

1( too. In #y opinion these t%o types do not really belong to the !an!ers so !alled byE%ing8 as their #etabolis#s are #u!h deeper and #ore differently deranged than %e see it inother !an!er types.

In the !ase of all of these diseases, %e ha$e !ause to assu#e that !on!o#itant da#age to theli$er has o!!urred as a result of per#anent into<i!ation or fun!tional disorders of theneighboring organs dropped sto#a!h8 or by vagus9sympaticus disturban!es in allergies8.Casi#ir ?un* pointed to the !lose !onne!tion bet%een li$er dysfun!tion, digesti$e disturban!esand allergi! diseases #any years ago.

In the beginning of the treat#ent so#e patients $o#it a great a#ount of bile and suffer fro# a*ind of to<i! diarrhea. They be!o#e e<!ited, franti! and %ant to dis!ontinue the treat#ent.These strong rea!tions are a!tually indi!ations of the beginning of i#pro$e#ent, %ith in!reased

bile produ!tion, greater a!ti$ity of the li$er and eli#ination of to<ins and poisons. fter a periodof one or t%o days, patients feel greatly relie$ed, sho% better !ir!ulation, !o#ple<ion and !olor,and ha$e #ore appetite. Then it %as found out that deto<i!ation !an be a!!elerated by thein!rease of !offee ene#as and additional !astor oil treat#ents !astor oil by #outh and !astor oilene#as8, and these $iolent rea!tions no longer o!!urred.

ee ppendi< III. page ;(1

"e see again the funda#ental i#portan!e of the li$er for re!o$eryO but %e should not forget thatthe fun!tion of the li$er depends upon the regulation of the $is!eral ner$ous syste#. Therefore,the dis!ontinuan!e of all sedati$es and #ost intensi$e eli#ination of to<ins and poisons areindispensable that #eans li$er and pan!reas apparatus ta*en as a %hole and the $is!eralner$ous syste# #ust be able to fun!tion freely.3i$er !an be ta*en as nourish#ent e$en by those allergi!O patients %ho are highly

hypersensiti$e to ani#al proteinsO as therapy, ho%e$er, li$er nutrition is not suffi!ient, but #ust be supported by a #ore spe!ifi! li$er therapy. "here stronger li$er sti#ulation appears ne!essary,as in !ases of serious into<i!ation and degenerati$e diseases, e<tensi$e li$er in5e!tions and li$er

5ui!eJ therapy are ne!essary. The !o#bination of li$er therapy and diet %as ne!essary in serious!ases of osteoarthritis, asth#a angina pe!toris and #alignan!ies. The !o#bination of a saltlessdiet, poor in fat and proteins, %ith the li$er therapy, regularly lo%ers the blood sugar!onsiderably, so that the diet in!reased the effe!t of the li$er enzy#es, in!reased the effe!t ofinsulin, and de!reased the adrenalin effe!t to a great e<tent. !!ording to Ernst 3eupold, the



C-APT1R =III

Scientists Term Radiation A Peril to ?uture of

Man<

#umulative %ffect

'/CP A> surprise %ere e<pressed by the !o##ittee on geneti!sin its finding that the #eri!an publi! %as using up about one third of the safety li#it in #edi!aland dental N-rays. Its #e#bers !alled on the #edi!al profession to redu!e the use of N-rays tothe lo%est li#it !onsistent %ith #edi!al ne!essity.

This !o##ittee also urged a national syste# of personal re!ords %hereby e$ery #eri!an%ould *no% his total a#ount of e<posure. The effe!t of radiation is !u#ulati$e, it is said, no #at-ter ho% long the period o$er %hi!h it is e<perien!ed.

The si< !o##ittees studied the radiation proble# in the fields of geneti!s, pathology,

#eteorology, o!eanography and fisheries, agri!ulture and food supplies, and disposal and dispersalof radioa!ti$e %astes. . . .2athologi!al effe!ts >r. hields "arren, Chair#anR6e!o##endations %ill be #ade in the

future. The !o##ittee !on!luded in agree#ent %ith geneti!ists that radiation, no #atter ho%s#all the dose, shortens life in so#e degree. . . .

>r. "ea$er&s geneti!s !o##ittee re!o##ended as a general population safety li#it thate<posure to radiation should be held do%n to 1 roentgens for the first years of a person&s life. roentgen is a unit for #easuring the har#ful ga##a ray fro# =edi!al and dental N-raye+uip#ent, nu!lear %eapons e<plosions and fro# natural !auses li*e !os#i! rays and naturalradiu#.

J nthony 3e$iero, "ew =ork Times, Lune 1, 19)4. ur$ey of a report held in the Aational !ade#y

of !ien!es, "ashington, >. C. on the iologi!al Effe!ts ofto#i! 6adiation.s a result of #edi!al N-rays it is esti#ated that ea!h person in this !ountry re!ei$es on the

a$erage a total a!!u#ulated dose to the gonads or se< glands about three roentgens in years./f !ourse, so#e persons get none at allO others #ay get a good deal. .. . >r. "ea$er de!lared it%as stupid geneti!ally to use N-ray for the fitting of shoes. 'e %as referring to the N-rayde$i!es that ha$e be!o#e !o##on in shoe stores and into %hi!h !hildren often stare in a%e,so#eti#es %ithout regard to ti#e at the shado%s of the bones of their feet.

>r. "ea$er also !onde#ned obstetri!ians %ho #a*e N-ray pi!tures of pregnant #others tosho% the# ho% beautifully for#ed is the s*eleton of their baby %ithout realizing the hazardsof the dose of three or four roentgens that is being ad#inistered.

In addition to si< long su##ary reports of the !o##ittees, the s!ientists also issued a report tothe publi! in the si#plest lan guage possible. 'ere the lay#an #ay read ho% radiation da#ageine$itably results fro# e<posure, no #atter ho% s#all the dose.

6adiation !auses #utation or har#ful !hanges in the genes or ger# !ells of the reprodu!ti$eorgans. >a#age #anifests itself in shortening of the life span, redu!es ability to produ!e!hildren, and so#eti#es, but not often, produ!es defor#ed or frea*ish !hildren.

E$en if the #utations is in one gene, there is so#e har#ful effe!t that #utation %ill go onthrough e$ery generation until the line that bears it be!o#es e<tin!t.

The report e<plained ho% e$ery !ell of a person&s body !ontains a great !olle!tion, passeddo%n fro# the parents, the parents& parents, and so on ba!*, of di$erse heredity units !alledgenes.

The lay#an&s report %ent on to e<plain?ro# the point of $ie% of the total and e$entual da#age to the entire population, e$ery#utation !auses roughly the sa#e a#ount of har#. This is be!ause #utant genes !an only



disappear %hen the inheritan!e line in %hi!h they are !arried dies out. In !ases of se$ere andob$ious da#age this #ay happen in the first generationO in other !ases it #ay re+uire hundredsof generations.

Thus, for the general population, and in the long run, a little radiation to a lot of people is ashar#ful as a lot of radiation to a fe%, sin!e the total nu#ber of #utant genes !an be the sa#e inthe t%o !ases.

ut da#age to future generations due to radiation %ill be diffi!ult to identify. The study ofgeneti!s da#age has only 5ust begun, %ith a report due on geneti! effe!ts obser$ed in the popu-lations of 'iroshi#a and Aagasa*i, the Lapanese !ities destroyed by #eri!an ato# bo#bs in"orld "ar II. . . .

The !o##ittee said the radiologists #ay %ell re!ei$e doses in the !ourse of their o!!upationranging fro# $ery slight to about 1, roentgens.

In fi<ing a reasonably safety li#it of 1 roentgens, the "ea$er panel !o##ented, nothar#less, #ind you, but reasonable. /f this safety li#it, the panel said, %e are no% using onthe a$erage so#e three or four roentgens for #edi!al N-rays.

This is roughly the sa#e as the una$oidable dose re!ei$ed fro# ba!*ground radiation, the"ea$er panel added. It is really $ery surprising and disturbing to realize that this figure is solarge, and !learly it is prudent to e<a#ine this situation !arefully. It is folly to in!ur any N-raye<posure to the gonads %hi!h !an be a$oided %ithout i#pairing #edi!al ser$i!e or progress.

"hile there e<ists no %ay of #easuring a dose of radiation sustained by se< organs, the"ea$er !o##ittee said that unless shielding %as used so#e part of e$ery dental or #edi!al N-ray rea!hed these organs. They said a dental N-ray %ould deli$er about .) roentgen to thegonads, and a general fluoros!opi! e<a#ination t%o or #ore roentgens.

In the last 1 years s!ien!e has introdu!ed into the !an!er therapy isotopesO radioa!ti$e iodine,!obalt, phosphorus, strontiu#, as %ell as proteins and hor#ones. In the beginning there %as alot of opti#is# about the ne% #ethods, but a great disillusion soon follo%ed. End of report.8

=y o%n e<perien!es sho% that the #a5ority of patients %ho had ; to : deep N-ray

treat#ents and, in addition, 14 to ; !obalt treat#ents !ould not re!o$er at all. o#e i#pro$edafter a #u!h longer period and others only partially,The follo%ing appeared in an arti!le on radiation in the "ew =ork Times on Luly (1, 19)7

Safety limit is set

s a safety li#it, the Aational !ade#y of !ien!es has re!o##ended,that the a$erage person re!ei$e not #ore than ten roentgens of #an-#ade radiation to thereprodu!ti$e organs fro# !on!eption to the age of .

The roentgen is a unit of #easure#ent of radiation dose.

The report also lends ne% support to the repeated %arnings of ato#i!

offi!ials and s!ientists that #an fa!es a far greater danger fro# #edi!al use of radiation than hedoes fro# the radio-a!ti$e fall-out fro# ato#i! testings.

si#ilar %arning !a#e last #onth fro# >r. 3eroy E. urney, urgeon General of the @nitedtates 2ubli! 'ealth er$i!e, %ho said that in $ie% of the in!reasing sour!es of radiation in thenu!lear age, the ti#e had !o#e to reassess the safe le$els of radiation fro# #edi!al treat#ent.

In re!ent years there has been an in!reasing a%areness in the #edi!al profession of the potential danger of radiation fro# N-ray treat#ents, and steps ha$e been instituted to li#it theradiation dose.

1STIMAT1 S112 -I!-

The report states that the esti#ate is probably a!!urate to %ithin a fa!tor or t%o. In other %ords,

the thirty-year dose to the gonads !ould be as lo% as t%o 6oentgens and as high as eight6oentgens. The belief a#ong so#e radiation e<perts is that, if anything, the esti#ate is on thehigh side.



e!ause of the ine$itable un!ertainty of statisti!al analyses of li#ited data, s!ientists arere!o##ending that a population sa#pling progra# be underta*en to deter#ine #ore e<a!tlyho% #u!h N-ray radiation is re!ei$ed by the a$erage person.

u!h sa#pling progra# is to he re!o##ended to the @nited Aations !ientifi! Co##ittee onthe Effe!ts of to#i! 6adiation by the International Co##issions on 6adiologi!al 2rote!tion and6adiologi!al @nits and =easure#ents.

C-APT1R =I.

Mineral Meta&olism in $egenerative $iseases

T'E GEAE63 approa!h to the treat#ent of patients %ith degenerati$e diseases should ha$e as its purpose the o$er!o#ing of the bio!he#i!al abnor#alities %hi!h are #ore or less responsible for

the de$elop#ent of the disease. I a# !on$in!ed that the proble# of !hroni! diseases is not one of bio!he#istry, !he#istry or the sy#pto#s %e obser$e in and on the body. 6ather, it is produ!ed by deeper-lying for!es %hi!h !ause defi!ien!y of energies. 2hysi!ians obser$e biologi!alsy#pto#s and %or* only %ith the#. The real a!ting for!es behind the $isible !he#i!al !hangesare physi!al energies, e<pressed by Einstein as the ele!tro-#agneti! field. To a !ertain degree,this is !losely !onne!ted %ith the ele!tri!al potentials %hi!h are lo%ered in !an!er, a!!ording toal#ost all in$estigators about 8 and also a!!ording to the obser$ations of >r. 6udolf Peller.

The abo$e-#entioned bio!he#i!al sy#pto#s are e<pressed in 'astings& Ter#inology asintra-!ellular or P-group #inerals in essential organs and the e<tra-!ellular or Aa-group#inerals in the fluids. 3aboratory findings re$eal that in !hroni! diseases, sodiu# and !al!iu#,

both negati$ely !harged, in$ade the %ea*er positi$ely !harged organsO a!!ordingly, P is lost

fro# these organs, opening the door to further negati$e #etaboli! transfor#ations. !ere thedisease starts, but not the symptoms.

It is #y opinion that P and Aa also play an i#portant role in the !an!er proble#. These t%o#inerals are the leaders of the t%o ele!tri!ally opposite groups. They are in !lose !onne!tion%ith the de$elop#ent and #aintenan!e of the hu#an body as %ell as %ith the origin and

progress of the disease. The hu#an organis# is, in e#bryoni! life and early infan!y, a sodiu#-ani#al, due to the relati$e preponderan!e of Aa throughout the entire organis#, but, in adult life,a potassiu#-ani#al. The potassiu# predo#inan!e #ust be #aintained throughout life. To a!ertain degree it gi$es the basis for i#portant de$elop#ents in both dire!tionsRnonnal andabnor#al. In this respe!t, the a#ount ofO #inerals is ne!essary but the degree of their ionizationis e+ually i#portant, parti!ularly in !an!er.

"e *no% no% that %hat %e ha$e inherited is not a set of !he#i!al substan!es, but a pattern ofdyna#i! energies, %hi!h dire!tly distribute and ionize the #inerals, hor#ones and enzy#es,et!., for har#oni! !ooperation %ithin li$ing !ells and tissues, %here they belong and in %hi!h%ay they ha$e to a!t and influen!e the gro%ing tissue. een fro# this point of $ie%, the !he#-i!al fa!ts as they appear in the laboratory findings ha$e the follo%ing line in our de$elop#entThe unfertilized hu#an egg !ell is 11 ## in size, full of P-group or intra!ellular #inerals P,2, =g, =n, Cu, ?e, u8, ele!tro-positi$e and has the !orresponding enzy#es, $ita#ins and

protein-!o#pounds, but the %hole is ina!ti$e, %aits and longs for ani#ation. The sper#, %hi!his 1( ## in size, !ontains the Aa-group #inerals ana is ele!tro-negati$e Aa, CI. '(/, I, r.l and the ionized part of Ca8, together %ith the other group of enzy#es and $ita#ins, but isa!ti$e and brings on enli$en#ent. The fertilized egg be!o#es, through a pro!ess of dis!hargingso#e !o#positions and absorbing a great deal of Aa fro# the surrounding ly#ph fluid,distin!tly negati$ely !hargedO a Aa-ani#ai is !reated and re#ains one throughout the entire

pregnan!y and up to si< #onths after birth ?ran* Golland8. The tables on pp. (), (4, (7 of



Chapter illustrate the different stages of de$elop#ent by ta*ing the AaP ratio as a guide.In studying these figures, %hi!h are based on laboratory findings, one has to a!!ept the strange

fa!t that these Aa-ri!h e#bryonal !ells ha$e, a!!ording to pe#an, organisator po%er, %hi!h!arry in the#sel$es the dyna#i! patterns of the prefor#ed future ani#al. The #onths of

pregnan!y and si< #onths of e<trauterine life ?ran* Golland8 are only a transitional stage of ali$ing being, %hi!h !ontinues to pass o$er into nor#al life %ith an e<!ess of P-group #inerals

in $ital organs, until disease or old age #a*es it lose so#e of the P-#inerals, together %ith the!orresponding enzy#e-fun!tions, et!. Ea!h !ell !arries in itself so#e potentialities of a nor#alli$ing !ell under nor#al internal and e<ternal en$iron#ental !onditions, or else they fall ba!* totheir original e#bryoni! state. 6. 6. pen!er and other in$estigators, %ith *een foresight,!o#pare !an!er !ells not to the !ells of old age but, rather, to e#bryoni! ones. /ne i#portantdifferen!e, ho%e$er, is that !an!er !ells are not supplied %ith ner$es and therefore la!* ner$ousregulation. The e<peri#ents of 3oh#ann re$ealed that #agnesiu# and #anganese, both#inerals of the P-group, inhibit the 2asteur effe!t there.

In The 4iochemistry of Malignant Tumors, the 2asteur effe!t is des!ribed as follo%s Thein!reased !on$ersion of #ethylgly-o<al to la!ti! a!id %hi!h thus #ay be indu!ed by thea!ti$ated enzy#e %as belie$ed to be responsible for the a!!u#ulation of la!ti! a!id in neoplas#,

and the rapid disappearan!e of #ethyl-glyo<al %as thought to interfere %ith the re-synthesis ofthis !o#pound to he<ose.:

Inas#u!h as our #ineral #etabolis# is dependent upon the food produ!ed by the soil, I %ouldli*e to refer to an introdu!tion to this sub5e!t by Charles E. Pellogg. The soil is the li$ing #atterat the surfa!e, and of the #ineral #atter beneath the surfa!e, and of the at#osphere abo$e andthe solid ro!* beneathRessentially all li$ing #atter depends upon it, dire!tly or indire!tly, is, infa!t, a part of those $ery pro!esses that produ!e the soil upon %hi!h life depends.

2lants and soils ha$e gro%n up together, ea!h partly a !ause of the otherR#an has so#e%hatthe sa#e relationship to the soils. 'e #ay !hange the#, either for better or for %orse.:1

$%&O'!L("I!

The leading #ineral of the negati$e group, potassiu#, plays an i#portant role in !lini!alsy#pto#atology, for e<a#ple, in The Bournal of the $M$, %e find the follo%ing su##ary:( Itis *no%n that P-defi!ien!y #ay o!!ur %hen the

: Purt tern and 6obert "iLlhei#, The 4iochemistry of Malignant Tumors,:1 Charles E. Pellogg, The oils That 'upport 6s, The =a!#illian Co., 19)4.:( ee The Bournal of the $merican Medical $ssociation, 1;, 19). p. ;(.

18 food sho%s di#inished !ontent of this #ineral.18 in !ases of $o#iting, !aused by #any reasons, also by ob stru!tion in !an!er.(8 in leu*e#ia, as leu*o!ytes attra!t large a#ounts of P.

8 in e<!essi$e diureses.(8 adreno-!orti!al hor#one fa$ors re-absorption of Aa and loss of P. If this hor#one is

o$er-a!ti$e, the !onse+uen!e is e<!es--si$e loss of P.

!=P%&@$%M<$

18 usually does not o!!ur as a result of oral ad#inistration as long as the *idneys are inta!t.(8 in !an!er, in ad$an!ed !ases, one finds hyper*ale#ia not too rarely, !aused by loss of P

fro# tissuesR now e<tra!ellular in the seru#, on the way to elimination.

8 in so#e !ases of renal insuffi!ien!y, also in depression, in dehydration and in so#efor#s of nephritis.

ased on other arti!les and #y o%n e<perien!e, I %ould li*e to gi$e the follo%ing su##ary ofhypo*ale#ia and hyper*ale#ia.



'F2/P3E=I

18 diabetesR#ore during insulin therapy.(8 intra$enous glu!ose and other in5e!tions, %hen free of P.8 Cushing&s syndro#e,

Glau!o#a2aralysis agitans

?re+uently in !hroni! arthritis, !hroni! sinusitisand other !hroni! diseases.

;8 follo%ing ad#inistration of Cortisone drenal !orte<8)8 undernourished patient, also fasting48 loss of P in $o#iting, diarrhea, gastri! su!tion.78 fa#iliar periodi! paralysis.:8 !an!erR#ostly in #ediu# or far ad$an!ed !ases.

!=P%&@$%M<$

18 loss of fluidsRblood, in #a5ority of !ases dehydration.(8 epilepsyR#ost !ases.8 !an!er patients #ore often in the period before they go o$er to the ter#inal stage on the

%ay to eli#ination8.;8 ne$er in !an!er patients during restoration ti#e.)8 ddison&s disease.48 anuriaRure#ia inability of fi$er and *idneys to e<!rete e<!ess potassiu# in solutionR

lost fro# essential organs878 a!ute and !hroni! asth#a, and other degenerati$e allergies also !raurosis $ul$ae8.

The !ontent of potassiu# in the seru# is, in #any !ases, #isleading. The latest arti!le ofu#ell and !ribner also tends in this dire!tion but starts to dra% attention to the obser$ation

that !hanges in the seru# potassiu# !on!entration refle!t !hanges in body need.:

=ye<perien!es are #ostly li#ited to !an!er !ases. The !ur$es of these patients o$er years are $erydiffi!ult to e$aluate. Aot one e<a#ination, but the !ur$e de!ides.8 ingle e<a#inations !an not

be regarded as an e<!ellent guide to the potassiu# need of patientsRas the abo$e-#entionedauthors say. It does not gi$e any definite indi!ation of an in!reasing or de!reasing a#ount of

potassiu# present in the tissues of essential organs. There are only a fe% e<a#inations #ade inseru# and tissues at the sa#e ti#e. =ore !oin!ident e<a#inations of P #ade at the sa#e ti#e inseru# and tissues and in different stages of the disease, are ne!essary for su!h de!isions.

2otassiu# appears to play an indispensable and uni+ue role in tissue protein synthesis,although the #e!hanis# of its utilization is at present un*no%n. 2otassiu# ions areindispensable in !ertain enzy#ati! rea!tions, and this #ay be a further reason for its urgent need.

It appears that the hea$y isotope @ * is definitely lo%er in tu#ors, as %ell as in tissues of tu#or- bearing ani#als.

=us!les, brain and li$er nor#ally ha$e a #u!h higher potassiu# !ontent than a sodiu#!ontent. It !an be a!!epted as a

: ee The Bournal of the $merican Medical $ssociation, ol. 14;, Ao. 9, Lune (9, 19)7, p. 9)9.JJ-ee , 3asnitz*i and . P. re%er, #ancer &esearch, (.;9;,19;(.

general rule that as long as potassiu# is nor#ally in the #a5ority, sodiu# is in the #inority. si#ilar relationship e<ists bet%een #agnesiu# and !al!iu#, so that %here #agnesiu# isin!reased, !al!iu# is di#inished.

Purt tern and 6obert "illhei# %rote that tu#or pro#oting property of potassiu# saltsad#inistered perorally or parenterally has been #ade $ery probable. The i#peding a!tion of!al!iu# salts is #u!h #ore proble#ati! and the alleged anti-plasti! +uality of #agnesiu# #ust

be regarded as %holly unfounded.:) In the older literature, !ontro$ersial opinions %ere



e<pressed regarding one of the #ost i#portant #ineral !onstituents of food, sodiu# !hloride.o#e authors suspe!ted this salt as the #ost sti#ulating neoplasti! gro%th agent anda!!ordingly, re!o##ended its restri!tion in the !an!er diet.:4 /ther !lini!al obser$ationsindi!ated that regi#es e<tre#ely poor in salt, su!h as ha$e been used for dietary treat#ent oftuber!ulosis,:7 e<ert a rather unfa$orable influen!e on hu#an neoplasia.::

The effe!ts of sodiu# !hloride on tu#ors %ere studied in a nu#ber of ani#al e<peri#ents

%hi!h %ere not !on!lusi$e. "hether !an!er %as sti#ulated by al*alosis or %as hindered by a!idfor#ation has been long disputed. ?inally, 6agnar erg strongly re5e!ted the $ie%point that diets

produ!ing al*alosis !ould be responsible for !an!er de$elop#ent,:9 In e$aluating #ost of thesestudies, one finds that all these atte#pts to !hange the hydrogen ion !on!entration in blood andtissues by spe!ial dietary !o#binations en!ounter great diffi!ulties, sin!e e$ery author usedso#e other food for that purpose. o#e of the authors used thy#us, an organ ri!h in protein andnu!lei! a!ids, but $ery poor in #ineralsO others used *idneys, li$ers and e<tra!ts prepared fro#different organs. !!ording to the !lini!al obser$ation that the in!iden!e of #alignant tu#ors inthe duodenu# and s#all intestines are e<tre#ely rare, they used for their e<peri#ents

:) Purt tern and 6obert "illhei#, The 4iochemistry of Malignant Tumors, p. ;1.

:4 . 3orandO 7irst <nternational #ancer #ongress, =adrid, (;:, 19.

:7 >r. =a< Gerson, Dietary Therapy of ung Tuberculosis, 19;.:: ?. lu#enthal, ?irst <nternational #ancer #ongress, =adrid 179, 19, E-

'esse, Deutsche Medi:inische ;ochenschrift, 41797, 19).:9 ee ?eitschrift fuer Aolksernaehrung, 9(77, 19;.

these organs in ani#als bearing transplanted tu#ors and in others to pre$ent any gro%th.lu#enthal and La!obs used a spe!ial e<tra!t of s#all intestines %ithout #u!h of a fa$orable

result.9 slightly #ore fa$orable result %as obtained by the feeding of the brain or e<tra!ts ofthis organ. These obser$ations, #ade by . '. 6offo, '. assiliades and C. 6ouss$ during 19)-197 are e<tre#ely interesting sin!e the substan!e of these organs are ri!h in lipids %hi!h ha$egenerally been found to sti#ulate tu#or gro%th. The de$elop#ent of tar !an!er in #i!e %asfound enhan!ed by the feeding of li$er or pan!reas to the ani#als,91 and the tu#or-sti#ulatingeffe!t of li$er feeding %as !onfir#ed in nu#erous studies of $arious tu#or-bearing ani#als. nentirely different effe!t of li$er feeding %as obser$ed by the produ!tion of li$er tu#ors in rats byfeeding butter yello%. This type of !ar!inogenesis !ould be pre$ented by a li$er diet. It isinteresting that feeding of li$er !ould only pre$ent !ar!inogeni! de$elop#ent of butter yello%,

but it !ould not pre$ent the tu#or produ!tion by benzpyrene or #ethyl!holanthrene. The !auseof these influen!es, %hi!h differ in $arious for#s of neoplas#s, %as not gi$en. Purt tern tenta-ti$ely assu#ed that the effe!ti$e un*no%n fa!tors #ay be of an enzy#ati! nature and that$ita#ins and these hypotheti!al agents #ay interfere %ith tu#or de$elop#ent and tu#or gro%th$ia #etaboli! #e!hanis#s. I ha$e e<pressed a si#ilar opinion in se$eral arti!les, and in this

boo* e<plained the use of fresh !alf s li$er 5ui!eJ in !an!er therapy. These !ontro$ersialobser$ations and des!riptions are !hosen to de#onstrate ho% !ontro$ersial the biologi!alliterature in !an!er is. ?or ea!h positi$e effe!t one !an find a negati$e one. Generalizations in!an!er are #ost diffi!ult to for#ulate. In #y opinion, the area %herein they #ay be possible %ill

be in the biologi!al field of ele!tri!al potentials, ionization of #inerals and rea!ti$ation ofenzy#es.

Greenstein has stated that In tu#ors in rats, #i!e or #an, the !atalyti! syste#s in$ol$ed inaerobi! o<idations are !onsiderably redu!ed as !o#pared %ith nor#a0 tissues and, indeed, inea!h spe!ies, are redu!ed to nearly the sa#e e<tent. high rate of gly!olysis, an in!reased%ater !ontent, and a lo% a!ti$ity of 9 ee ?eitschrift fuer @rebsfbrchung, ".);), 19. :1 . ?"atson, $merican Bournal of #ancer, 19:9, 19. ee ppendi< III. page ;(1

!yto!hro#e are a#ong the !hara!teristi!s of pra!ti!ally all tu#ors in all spe!ies studied. Aearly allrapidly gro%ing tu#ors in #i!e. and rats produ!e identi!al syste#i! effe!ts in the host ani#als, as



sho%n by the #ar*ed redu!tion in li$er !atalase a!ti$ity.9(

Can!er is the #ost $ariable disease %e ha$e for %hi!h there are thousands of different na#es.The beginning !an be #ost a!ute or $ery !hroni!, the !ourse tedious or rapid, the !o#pli!ationsinnu#erable, and it !an be !o#bined %ith #any different defi!ien!ies, %ith high or lo% blood

pressure, %ith diabetes, arterios!lerosis and other diseases of old age. t the end, the into<i!a--tion in!reases and the li$er deteriorates. =ost of our life is built upon the a!ti$ation and

#aintenan!e of the li$ing pro!esses. These are based on the #ineral #etabolis# and fun!tion ofthe li$erR%hi!h a!ts li*e !hlorophyll in plantsRa!!epting ions front the sun and transfor#ingthe# as life begets life. "hat Aature does in that %onderful, subtle for# by transfor#ationsand !o#binations %ith these ions we !annot i#itate biologi!ally. Therefore, it see#s to #ead$isable not to attack the cancer directly %ith N-6ays, radiu# or !obalt and da#age at the sa#eti#e the other parts of the body and its healing po%er. The #ore the %hole body is deto<ified,replenished and a!ti$ated, the #ore the !an!er is doo#ed.

The rare in!iden!e of #alignant tu#ors in !ountries %here garli! is used in greater a#ountssouthern Italy, Gree!e, =ontenegro, Fugosla$ia8 !annot be e<plained. I ha$e seen t%o !an!ers ofthe breast disappear %ith the use of ?enugree* seeds tea in large a#ounts, !o#bined %ith asaltless $egetarian diet. T%o others %ere !ured after the patients dran* green leaf 5ui!e only for

si< to eight #onths.The transfor#ation of the #inerals in the body and bringing the# in suffi!ient nu#bers into the

organs, %here they belong, is a $ery diffi!ult and !o#ple< tas*. spe!ial relationship e<ists bet%een sodiu#, !hloride, and a#ino a!ids, %hi!h see# to parallel the a#ount of ede#a in the body. /n the other hand, potassiu# belongs to a group %hi!h is asso!iated %ith phosphori! a!idsand !arbohydrates and is able to !o#bine %ith these !ol loids. It is, therefore, #ore reasonable tospea* of the potassiu# group and the sodiu# group as 6udolf Peller does.

9(Lesse Greenstein, 4iochemistry of #ancer, p. ):9, 19);.

The effe!t of the diet is that the potassiu# group is enri!hed in the essential organs and the

abnor#al sodiu# !ontent in these organs redu!ed to a #ini#u# and eli#inated into the e<tra-!ellular fluids, %here they belong.The e<tra!ellular fluids %hi!h !o#prise the blood plas#a, the tissue or interstitial fluid, ly#ph

and fluid in serous !a$ities, a#ount to about ( per !ent of the body %eight. The plas#a %ater!onstitutes only about four and one-half per !ent of the body %eight. The fluids %ithin the !ellsa#ount to ) per !ent of the %eight of the body, or t%o and one-half ti#es the e<tra!ellularfluids. The s*eletal #us!les !ontain about ) per !ent, the s*in about ( per !ent, and the %hole

blood only about 1 per !ent of the total body %ater. In general, the intra!ellular fluids ha$e ahigh potassiu# !ontent and a lo% !on!entration of sodiu#, %hereas the e<tra!ellular fluids ha$elarge a#ounts of sodiu# and s#all a#ounts of potassiu#. The %ater !ontent of $arious tissues in

a$erage per!entage is ta*en fro# a table9



The higher sodiu# !hloride !ontent in the urine of !an!er patients during the first %ee*s of thesaltless treat#ent pro$es that sodiu# !hloride and %ater are retained in !an!er patients. The#a5ority of the patients did not sho% any type of definite ede#a on the s*in. fe% of the# %ere

e$en undernourished, see#ingly dried out and e#a!iated, but still eli#inated $ery large +uantitiesof sodiu# !hloride in their urine, espe!ially at first. The retention %as probably in the internalorgans.

9: est and Taylor, The Physlological 4ash of Medical Practice, "illia#s and"il*ins Co., alti#ore, 19), p, 19.

If %e !onte#plate the #ineral #etabolis# as the basis for the !onstru!tion of !ells, %e ha$e toloo* into an in$isible #ineral !ir!ulation %ith a great storage po%er of the #inerals of the

potassiu# group and gly!ogen in the li$er and e+ually for iodine and the #inerals of the sodiu#group in the thyroid gland. If these #ineral groups are partly displa!ed as %e see in #ost a!ute as

%ell as !hroni! diseases, %e find si#ultaneously lo%er ele!tri!al potentials in the tissues andseru#. Conse+uently, the storage po%er is s#aller and the flo% from, the storage #agazines isgreater as the !ells lose their nor#al attra!tion po%er %ith the lo%ered potentials. This s#allerattra!tion po%er results in redu!ed storage of gly!ogen in li$er and #us!les and also in fe%er#inerals of the potassiu# group, %hile in the thyroid, the s*in and other #ainly negati$e tissues,the iodine and e<tra!ellular ele#ents, sho% defi!ien!ies or displa!e#ents.

The i#portan!e of potassiu#, iodine and blood sugar leads the physi!ians #ore and #ore to pursue these tests in al#ost all patients, as they gi$e us $aluable infor#ation not only about these#entioned substan!es but also about #any other !lini!al pro!esses. To ha$e a better insight intothe !lini!al pro!esses of our patients, it is not suffi!ient to e<a#ine single substan!es, sin!e %elearn that a single substan!e does not tra$el alone fro# the blood to the tissue !ells or in$ersely.

To !onfir# this, one #ay stain a !ell %ith #any dyesO one single #i!ros!opi! !ell or part of it%ill not a!!ept the stain of one dye only.

ehind the #etabolis# of #inerals and #atter there is a po%er of energy, an ele!trostati! andan ele!trodyna#i! one, and probably se$eral other energies, %hi!h are the sti#ulating po%ersfor all #o$e#ents of #atter. /ne should not thin* of #atter in +uantities or +ualities only butalso should ta*e into a!!ount the +uantities of energies %hi!h radiate fro# ionized #inerals, andshould sti#ulate and *eep all i#portant and $ital fun!tions of the !ells a!ti$e.

s '. Paunitz and . !hober ha$e sho%n, the ele!tri!al potentials of li$er and #us!les %entdo%n by #illi$olt or #ore after they in5e!ted diphtheria to<in or other poisons into the bloodstrea# of a rabbit. fter a fe% #inutes one !ould obser$e %ith a #i!ros!ope that so#e poisonsentered the paren!hy#a !ells %hi!h %ere repelled beforehand by the sa#e !ells. fter one-half

hour a +uantity of sodiu# appeared in the li$er paren!hy#a. This e<peri#ent, #ade in 194,!learly sho%s that

18 into<i!ation is the first effe!t, %hi!h is follo%ed by(8 loss of ele!tri!al potentials and8 loss of potassiu# #inerals.

This test de#onstrates also the !entral position of the li$er inall these pro!esses. ?or !enturies it %as assu#ed by good !lini!ians that !hanges in the li$er%ere the beginning of al#ost all diseases. s the li$er gradually loses a part of its ele!trostati!#aintenan!e po%er for reser$es, it !annot support the entire body nor#ally any longer fro# itsreser$es of gly!ogen, #any #inerals, $ita#ins and enzy#es, espe!ially during the night, but !an

store the# during the dayti#e. P. '. auer %rote great progress in the proble# of !an!erde$elop#ent is the re!ognition that it belongs to the general biology. The !ells in$ol$ed are!hanged into a different life e<isten!e. The fa!t that all *inds of tu#ors !an be present in all



li$ing organis#s is the !onfir#ation of those findings. . . . "ithin all li$ing beings the !apa!itye<ists to fall si!* %ith !an!er, %hi!h is a property of all tissues and organs.9;

To bring the syste# to nor#al or near to nor#al for healing purposes, it needs ani#atingenergies besides the pure substan!es %ithout %hi!h it is unable to a!t, !ooperate and fulfill dutiesfor #etabolis# and distribution. It is i#possible to li$e %ithout the energies %hi!h are #o$ingall substan!es all o$er the body and are supporting all !ells.

The atte#pts of old and ne% #edi!al authors to abandon the #ost spe!ifi! #ethods or thesy#pto#ati! treat#ents and to rely upon and to stress the !on!eption of totality ha$e #anyad$antages. 2utting the positi$e !enter of the li$er and the negati$e !enter of the thyroid #ore inthe foreground is ne!essary for this therapy.

There are so#e parti!ular details in the #ineral #etabolis# %hi!h !hara!terize the ne%treat#ent. ?irst, there is the artifi!ial nia!in besides the i#portant potassiu#. Aia!in sho%ed$ery good !linii!al results %hen ad#inistered in large doses, si< to eight ti#es

9; P. '. auer, Das @rebsproblem, p, 471.

) #g. a day it is the so-!alled pellagra pre$enti$e fa!tor, also *no%n as ita#in :8. The

theoreti!al e<planation %as gi$en later by >r. ". eiglboe!*, %ho pro$ed in ani#al e<peri#entsthat it is a potential restorer and raises the depleted li$er stores of gly!ogen. ". /. ?enn alsothin*s that it restores the depleted potassiu# stores in the li$er. Aia!in is not only a $ita#in,indispensable for the protein #etabolis#, but also is, as El$eh5e# and others sho%ed, an effi!ientrestorer of !ell energies in a great nu#ber of diseases fro# the !o##on !old to !an!er.

nother !hara!teristi! feature of the treat#ent is the liberal use of iodine in the inorgani! for#of lugol-solution and the organi! for# of thyroid. oth are strong restorers of the ele!tri!al

potentials and !ell a!ti$ity. The thyroid gland stores only ( per !ent of all the body&s iodine!ontent. The rest of the body&s iodine is !ontained in the s*eletal #us!les, the li$er and !entralner$ous syste#, but it is also relati$ely highly !on!entrated in the pituitary gland and in theo$aries. The thyroid gland ta*es up about : ti#es #ore iodine than does any other tissue. To

help the body in the o<idation po%er, iodine #ust be radioa!ti$e I1 and I118. The I1 isotopehas the longest half life eight days8.

In !an!er patients %e obser$e that the basal #etabolis# !an be $ery high, up to 4: or do%n to#inus 4. Corresponding is the iodine !ontent of the blood seru# abo$e or belo% nor#al and it!an be $ery e<!essi$e in both dire!tions, parti!ularly in #ore ad$an!ed !ases. "ith the therapythe high iodine !ontent !an be brought to nor#al or belo% nor#al in a relati$ely short ti#e, fro#1-( days. That #eans that the body %as losing great a#ounts of iodine at the beginning of thetreat#ent and the therapy re$ersed this pro!ess. $ery lo% iodine !ontent #ay indi!ate that the

body had already lost #ost of its iodine reser$es and no% absorbs iodine during the therapy inrelati$ely great +uantities. Aot one e<a#ination, but the !ur$e de!ides.

It is generally a!!epted that the organi! iodine of the blood, seru# is a #ore reliable inde< thanthe #etaboli! rate, as the latter is not !ontrolled e<!lusi$ely by the thyroid. Iodine see#s to playan i#portant role in tu#ors the#sel$es. In #ouse and rat tu#ors the iodine !on!entration %asfound to e<!eed that of li$er and #us!le.

The iodine deposition in tu#ors is a debated +uestion. It is reported increased by other authors, but only after the onset of regressi$e !hanges in the tu#or.

n interesting report by Greenstein states that I11 in the blood of nor#al and tu#or bearing

#i!e is the sa#e, but the decreased !apa!ity of tu#or-#i!e in !on!entration of ad#inistered I11

is probably related to so#e !hange in the physiology of the thyroid glands the#sel$es.9) It%ould be shortsighted, e$en in!orre!t, to obser$e one of the #ineral substan!es alone, or a groupof the#. <nnumerable metabolisms continue to act simultaneously, and many abnormal steps

have to be made until a symptom appears. The !lini!al signs are then un!hara!teristi!, su!h asfatigue, %ea*ness, easy e<haustion, #ore e<!itabilityRall these !an be due to #any differentdefi!ien!ies or !auses. To sti#ulate the body %ith one or another $ita#in, or a group of the#, or



a #i<ture of the# %ith #inerals, #ay help for a short %hile. It is a diffi!ult de!ision todeter#ine %here to sti#ulate and %here only to replenish the organs. This is a diffi!ult tas*

be!ause the organs #ay ha$e de$eloped so#e pathologi!al alterations in the #eanti#e. lar#sy#pto#s or spe!ial infe!tions #ay be e<!eptions but these are li#ited to a short period andre+uire sy#pto#ati! treat#ent.

In #ost situations, espe!ially in !hroni! and degenerati$e diseases, it is #u!h safer and #ore

fa$orable for the organis# to be helped in its totalityO this #eans the entire #etabolis# #ust berestored to nor#al or near-nor#al fun!tions.

s far as the #ineral #etabolis# is !on!erned, it see#s to be the basis for the a!ti$ede$elop#ent of a #alignan!y in a poisoned body. The #ineral #etabolis# in itself is not enoughto e<plain the nu#ber of fa!tors in$ol$ed in that biologi!al situation. It see#s to be the general

basis on %hi!h #any different defi!ien!ies o!!ur %ith serious !onse+uen!es in the #etaboli! pro!esses of protein, fats, and, to a lesser degree, in !arbohydrates. @nder su!h !onditions thedigestion and o<idation to the end produ!ts are progressi$ely da#aged. I %ill try to gi$e anappro<i#ate pi!ture about a !on!eption of nor#al life and the de$iation into !an!er.

Lesse Greenstein, 4iochemistry of #ancer, p. ((.

ife means #ancer means

1. =aintenan!e of the nor#al 1. lo% into<i!ation and alter-

#etabolis#, its regulations ation of the %hole body,and produ!tions for hor#ones,enzy#es, !oenzy#es, et!.,absorption and eli#ination po%er.

espe!ially the li$er.

(. =aintainin the re$alen!e (. In$asion of the Aa- rou ,of the potassiu# group in loss of P-group, follo%ed by

$ital organs and Aa-group #ainlyoutside in the fluids and so#e tissues. tissue ede#a.

. Peeping the positi$e ele!- . 3o%er ele!tri!al potentialstri!al otentials of the !ells in $ital or ans, #ore ede#a,high as the basis for energy a!!u#ulation of poisons,and fun!tion si#ultane- loss of tension tonus re-ously as a defense against du!ed rea!ti$ation and o<i-in$asion of the Aa-group dation po%er, dedifferentia-and the for#ation of ede#a. tion of so#e !ells.

;. =aintenan!e of !ir!ulation, ;. Can!er startsRgeneral poi-tension tonus stora e !a- sonin in!reases $ital fun!-

pa!ity, reser$es. tions and energies de!rease R!an!er

) 6ea!ti$ation po%er of $ital ). ?urther destru!tion of the

substan!es, espe!ially en- #etabolis# and li$er par-zy#es. en!hy# R !an!er rules R is a!ting,

s readin .4 >efense and healing po%er. 4. 3oss of last defenseRhepati!

!o#aRdeath.

I %ould li*e to say a %ord about the proble# of trans#iner-alization in our body. I *no% ho%

diffi!ult it is for physi!ians to ta*e a positi$e stand on that proble#. on erg#ann hoped thatthe ti#e %ill !o#e %hen %e %ill learn to add the defi!ient substan!es therapeuti!ally. I %ouldli*e to for#ulate this hope differently, as I thin* the ti#e %ill !o#e %hen %e %ill learn,a!!ording to the !on!ept of totality, to add in the right !o#position, the substan!es %hi!h %e find



to be la!*ing. t the sa#e ti#e the other substan!es and poisons %hi!h %e found to beantagonisti! or !ountera!ting ha$e to be eli#inated. The proble# of trans#ineralization is not yetre!ognized thoroughly enough to sho% all the therapeuti! diffi!ulties %hi!h ha$e to be o$er!o#eto restore the disturbed har#ony in the #ineral #etabolis#, step by step. ?ro# #y o%n !lini!ale<peri#ents I ha$e learned that it is not only ne!essary to !hange the #etabolis# in one or anothersubstan!e, but it is also ne!essary to !hange the inta*e of proteins, enzy#es, $ita#ins, et!.,

si#ultaneously to a!ti$ate all natural healing for!es %hi!h %e need for our therapy,

C-APT1R =.

$istri&ution of 1n@ymes in 5rgans=AF @T'/6 !o##ent as P. '. auer says in his boo* The #ancer Problem page 1148translated, one en!ounters again and again in the literature the !on$i!tion the riddle of !an!er!an be sol$ed by !he#istry of enzy#es . . .- or by bio!he#istry as >r. 6ad$in reported in theenate 'earing 19)7.

I thin* it %ill not be this %ay. It should be pointed out the !onditions in the !ells ha$e to be basi!ally and fun!tionally !hanged firstO the %hole #etabolis# in ea!h !ell is pathologi!allytransfor#ed in its protein and fat digestion and e<!hange. That !hange transfor#s auto#ati!allythe enzy#e-#etabolis#s %hi!h are ad5ust#ents to the pre!eding pathologies.

2ra!ti!ally all rea!tions %hi!h o!!ur in organis#s !an be attributed to the a!tion of theenzy#es.97 The enzy#es ha$e an e<tre#ely spe!ifi! a!tion, in order to #a*e a rea!tion ta*e

pla!e a !ertain resistan!e in the !ell is to be o$er!o#e. That #eans the #ole!ules %ithin the!ells #ust be a!ti$atedO a !ertain a#ount of a!ti$ation energy has to be supplied by the body fore<a#pleRin the !ells gly!ogen is bro*en do%n to !arbon dio<ide and %ater by a large nu#ber ofenzy#ati! rea!tions. This is the #ost si#ple !ell #etaboli! fun!tion and #aintained for the

longer period, %hile protein and fat #etabolis#s are in the sa#e !ells and at the sa#e ti#e+ui!*er and farther rea!hing deranged.Enzy#es fun!tion as they are #ostly organized in !hain rea!tionsRso#e are ine<tri!ably

!onne!ted %ith the li$ing organis#, they !an not be e<tra!ted, %ith inta!t a!ti$ity, fro# !ells or :4 P. '. auer, Das @rebsproblem, p. 114.97 La#es . u#ner and Parl =yrba!*, The %n:ymes, !ade#i! 2ress, 19), 2. 1.

tissues. Therefore t%o types of enzy#es %ere in e<isten!e

dis!e#able8

1.8 Enzy#es that !an be se!reted and e<tra!ted.

(.8 Enzy#es %hi!h are ine<tri!able fi<ed in the !ells8.Enzy#es !an be rea!ti$ated in the li$er and ha$e to be supplied to the !ells.

The !onse+uen!es for the !an!er therapy are, that for the restoration of enzy#ati! fun!tions the!ontent of the !ells has to be restored. That is i#possible in !an!er !ellsRpossible and ne!essaryin the other !ells.

ll in$estigators found that #alignant tu#ors are !hara!terized by a !onsiderableele!tronegati$ity in the tissues and fluidsO tarting fro# this pre#ise, I loo*ed o$er thea!!u#ulations of #inerals in nor#al and abnor#al tissues and their ele!tropolarity. I found a!enter of high ele!tronegati$ity in the thyroid, based upon the a!!u#ulation of an e<tra!ellulargroup. The !lassifi!ation in e<tra!ellular negati$e8 and intra!ellular positi$e8 substan!es is!orre!t for inorganic minerals in ele!tri!al !urrents.9: In biologi!al e<peri#ents of li$ing tissue,

ho%e$er, 'oeber dis!o$ered so#e stri*ing de$iations, !onfir#ed by later authors, =atsuo,"ilbrand, and others.

The follo%ing table !onsists of the !lassi!al lyophile groups fro# 'ofraeister and piro in the



order of 'oeber&s findings HContrary to the findings in inorgani! ele!tro!he#istry P potas-siu#8 is negati$e, tra$eling to the anode "aels!h 19;8 %hile Aa. I. r. is ele!tropositi$e,tra$eling to the !athode Peller 198. In this boo* and other literature the #inerals are!hara!terized as positi$e a!!ording to the organs %here they are deposited in the #a5ority.

T!BL( )

Electropositi%e orderline Electronegative

3i, Aa, l, ?l Co. 6b, C, P A';

CA, I, Ao r Cl Acetate, /; 2/; tartrate.

This table sho%s the antagonis# of the e<tra!ellular group-positi$ating, to the intra!ellulargroupRnegati$ating both a!!ording to 'oeber8.

9: !andbook of "utrition, #eri!an =edi!al sso!iation, 19;, p. 97, Table (.

s the first step, it %as found that the #inerals are deposited preponderantly either in the positi$e or negati$e sense in the organs of the body. s a !onse+uen!e, one !ould differentiate

the organs in pre$alent positi$e or negati$e organs, as !onfir#ed by #easure#ents #ade byPaunitz and !hober.

s a se!ond step, it %as re$ealed that #any organi! substan!es sho% a !hara!teristi! ele!tri!!harge by being a!!u#ulated predo#inantly in #ore positi$e organs or in #ore negati$e fluids,!onne!ti$e tissue, thyroid, spleen, parietal !ells, sper#atozoas, gro%ing #alignan!ies.

s a further step, I tried to study the distribution of enzy#es in different organsO there itappears to be a !hara!teristi! !lassifi!ation of one *ind of enzy#es in these and another *ind ofenzy#es in other organs.

?or so#e years, '. . urr and his !ollaborators published #any signifi!ant fa!ts !on!erningthe ele!tropolarity of #alignant gro%th. The first i#portant dis!o$ery %as the obser$ation that a

bioele!tri!al alteration %as found to pre!ede the tu#or de$elop#ent, and the se!ond, that all

#alignant tu#ors are ele!tronegati$e0 The late G. ". Crile, and his !ollaborators, =. Tel*es and. ?. 6o%land, found a de!reased ele!tri! polarization and an in!reased ele!tri! !ondu!ti$ity in#alignant tu#ors %hi!h #ay be !aused, in #y opinion, by the greater sodiu# !ontent in thegro%ing part of the tu#or Good#an and others8. e$eral in$estigators found, %ithoute<!eption, #alignant tu#or tissue negati$e by 1-( #illi$olts %ith unpolarizable ele!trodes,%hereas by using redo< ele!trodes greater potentials %ere found %hi!h a#ounted to 1#illi$olts and #ore, as unpolarizable ele!trode #easures the ions and #etal ele!trodes theele!trons.

s one indi!ator for ele!tropolarity, there %as found, for instan!e, the distribution bet%een blood !orpus!les intra!ellular, the ele!tronegati$e substan!es8 and seru# e<tra!ellular, positi$esubstan!es8. s another fa!tor, there !ould be used the a!!u#ulation in organs su!h as the li$er,

ner$e, brain, #us!le, !orte< of *idney or the a!inus of pan!reas, all preponderantly positi$e or-gans storing #ostly negati$e intra!ellular #atter %hereas the !utis of the s*in, #edulla of the*idney, !olloid of the thyroid and thy#us, sto#a!h and distal intestinal #u!osa, bile !apillariesand the !onne!ti$e tissues attra!t positi$e fro# e<tra!ellular #atter, repelling nor#ally the other.I ha$e sele!ted an author %ho did not use the %ord ele!tri!ity in his bio!he#i!al %or*s and doesnot propagate any hypothesis. The follo%ing tables are e<a#ples ta*en fro# Lesse 2. Greenstein&stables.



the proportion of the a!ti$ity of the organs for ne%ly in5e!ted potassiu# is not identi!al %iththeir !ontents in another stage, and it is also not perfe!tly identi!al %ith other analyses of thesa#e ani#al in other stages or %ith the !ontents of other biologi!ally negati$e or intra!ellular#etals or organi! !o#poundsO but in all !ases there is a !lose si#ilarity of the distribution of#any enzy#es to the a$idity for radioa!ti$e isotopes.

1 5p. cit p. 19:.11 Lesse Greenstein, 4iochemistry of #ancer, p. (4), Table 3NNI1.1( Quoted fro# y#posiu# on &espiratory %n:ymes, @ni$. of "is!onsin 2ress,

T$4% <<< Rin positi$e organs

Polonium Radio Isotope

=us!le 119 1.)

Testis 11 1.)3i$er :7 (.;Intestine 9 1.9

'eart :9 ).43ung :9 (.1rain :7 .1;*idne 4 1.)

Aer$e ) .(one ()4 .((*in (7 .42las#a ).) .1)

In su!h tissues as the li$er, lung, bone, and testis, the figures for intra!ellular #atter alone donot gi$e an a!!urate pi!ture be!ause these organs !ontain large a#ounts of the antagonisti!

groups. The bones, #oreo$er, are a !rystalline solid substan!e %hi!h !ontain large a#ounts outof proportion %ith the !ontents in protoplas#ati! %ater-ri!h tissues. The high P-!ontent of testisis also surprising.

@3?I>E

Ao% another e<a#ple of a positi$e #ineral tra$eling #ostly to the negati$eorgans.

TABLE IVIn the positi%e &r'ans In the ne'ati%e &r'ans

(i%er 0)*! +idney 030

bile syste#8 neg !orte< positi$e, #edullarain .: negati$e8=us!le .1 leen .1:6ed !ells .1 3un s .172an!reas .;7 Thyroid .1) islands Ae ati$e to#a!h .(;

Intestines .:1

#u! #e#brane negati$eO#us!le, ner$es positi$e8

The #ethods of deter#ination of enzy#es ha$e not yet rea!hed the a!!ura!y of the #odern

deter#ination of #inerals. E$en the figures for sulfide sulphur in the $ery a!!urate radioa!ti$e!ounter #ethod gi$e rather different resultsO for instan!e, in only four rats used in e<peri#ents by >, >, >zie%ia*o%s*i



t%i!e the #a<i#u# %as found in #us!le and t%i!e in s*in, the #ini#u# t%i!e in li$er, on!e ins*in, on!e in hair.1

The !on!entration of the enzy#es is $aried at different ti#es in different ani#als and !annot be!o#pared %ith inorgani! analyti!al results as analyzed by present #ethods. "ith regard to thegreat diffi!ulties in arri$ing at a !orre!t approa!h to an enzy#e distribution in !o#parison %iththe #ineral distribution, there is still a re#ar*able possibility of indi!ation in the antagonis#.

/ne has to *eep in #ind that enzy#ati! a!tion is funda#entally influen!ed by !he#i!al fa!torsother than ele!tropolarity the !o#parison %ith ele!tropolarity #ay in one or another !ase also

be a help in !ontrolling enzy#e analyses.The ele!tri! fa!tor of the #o$e#ent of fer#ents is only one of #any in $arious organs.

Transaminase $ctivities

?ollo%ing are the $alues of Ht in different rat tissues of gluta#i! a!id and pyru$i! a!id.1;

heart 7s*el. #us!le 1

brain (li$er ;4*idney

=. G. Pritz#ann reported +uestionable transa#inase a!ti$ity in #alignant tissues and none ins#ooth #us!le !hi!*en gizzard8, lung, erythro!ytes.1) lso Euler, Gunther, and ?ors#ann,found lo% transa#ination $alues for #alignan!y.1:

If this theoreti!al approa!h is useful, and if the distribution of the organic substan!es is predo#inantly influen!ed by their ele!tri! !harge, then %e #ay hope to find out in %hi!h organthese e<tra!ellular and intra!ellular substan!es are stored. "hen %e find in %hi!h organs tolo!ate the reser$e stores of a8 #inerals, b8 organi! substan!es, !8 the *ind of ele!tropolarity,

then it %ill be possible to lo!alize the different enzy#es, too.1: ee The Bournal of 4iological #hemistry, 14;14), 19;4.1; 2hillip 2. Cohen, 'ymposium on &espiratory %n:ymes, 19;(, p. (19.1) ee %n:ymologia, );;,19:.14 ee ?eitschrift flier @rebsforschung, ;9;4, 199.

Conclusions

The #ost stri*ing feature in this re$ie% of tables is that the li$er paren!hy#a is the #ost positi$ely !harged organ !ontaining $ery often #ost of the intra!ellular group, %hereas thethyroid is the #ost negati$ely !harged organ !ontaining a #ar*ed a!!u#ulation of the

e<tra!ellular group 4 Aa ; P in #illie+ui$alents8. It is re#ar*able that the enzy#es aredistributed a!!ording to these interpretations, in li$er, #us!le and heart on one side, and inthyroid, spleen and #alignan!ies on the other side.

C-APT1R =.I

Mineral Accumulations in the Thyroid

I A C/AAECTI/A %ith so#e proble#s of !hroni! diseases %hi!h respond to the ad#inistration of

iodine but are not !lassified as iodine defi!ien!ies, it see#s ad$isable to learn %hether #ineralsother than iodine in the so-!alled e<tra!ellular group Aa, r, rs, ?, et!.8 are disturbed in their#etabolis# and stored in the thyroid. s a funda#ental first step, a deter#ination of the Aa-!ontent of a nor#al thyroid gland and its relation to P, the leading #ineral of the intra!ellular



group, is assu#ed to be essential. If %e *no% that Aa is pre$alent in any organ, and thus the proportion bet%een P and Aa in #illie+ui$alents is s#aller than one, %e %ill also find in thisorgan the other #inerals of the e<tra!ellular group Cl, Ca, '(/, and others in!reased. If %e find#ore P than Aa, then, as '. Paunitz, E. 2. ?is!her, and 6. Peller ha$e sho%n, there are also other#inerals of the intra!ellular P-group a!!u#ulated in this organ. The analyses of la#b thyroidssho%ed the follo%ing

TABLE 1

+ mg % Na mg % a In millimols A 0)-0. 0)!/ 0)..1 0)!*0 0)S0 0)*0C 0)!3 0)!S 0)/2 0)!"3 0)!" 0).!

!!u#ulations of #inerals in the thyroid !o#pared %ith sub#a<illaris glandsfro# ratsK E<a#ined in 3aboratory of College of 2hysi!ians and urgeons, Ae% For*. 11

Sex no) 4et 4ei'th ,a + +5,aGrams 6 6 ratio

A 7 * /)!3/ 0)!3 0)3! !)31 F 3 !)!/ 0)!-! 0)30 !)S0C F * -)-! 0)!-! 0)33* !)32 F * !)0/ 0)0". 0)3! !)"-E 7 * -)/00 0)!-! 0)3*3 !).

This is only one e<a#ple of the pre$alen!e of P, the intra!ellular group, %hi!h is found insub#a<illaris glands and #ost of the other organs of adult ani#als #us!les, heart, li$er, *idney

!orte<, adrenals, brain, erythro!ytes, et!., %hi!h all together !o#prise about 4 per !ent of the body. The !ontent of the Aa-gronp is pre$alent in about (9 per !ent of the body and 11 per !entare on the borderline.

The abo$e-+uoted in$estigators ha$e de#onstrated that the P or intra!ellular group is ele!tro-negati$e in biologi!al surroundings and the Aa or e<tra!ellular group is biologi!ally positi$e. TheP-group, therefore, tra$els to the positi$e !ells and the Aa-group to the negati$e !ells and fluids.This is the reason %hy %e e<pe!t a surplus of ele!tropositi$e Aa in the thyroid after ele!tro-negati$ity has been found in this organ. /n the other hand, a predo#inan!e of either Aa or P inthe #ole!ular PAa ratio gi$es us an e<!ellent indi!ation of %hat other #inerals %e #ay e<pe!tto find in an organ, su!h as the thyroid gland.

The thyroid has, !ontrary to #ost of the other organs #ore sodiu# than potassiu# #ols in

#illie+ui$alents per !ent. The sodiu# !ontent is greater be!ause of the #ain !ontent in the Aa-ri!h !olloid, %hile the epitheliu# !ells !ontain !onsiderable a#ounts of P in the positi$e granulaand ha$e #any P-ri!h erythro!ytes. The negati$ity is !entered in the !olloid, a parado< %hi!h!an only be e<plained by an ele!trolyti! pro!essO si#ilar findings are found in a nu#ber of plantand ani#al tissues. >. Gi!*lhorn des!ribed 19()8 that al*aline root !ells of 'inapsis alba #a*ethe surrounding soil a!id, and A. 'enning found a si#ilar situation produ!ed by parietal !ells ofthe sto#a!h. 3i$ing !ells are apparently able to send out ele!tri!al potentials to%ard the outsideinto the dead spa!e of the thyroid folli!le or the open spa!e of the sto#a!h.

The ele!trostati! hypothesis !lai#s that in li$ing protoplas#s the ele!tri!al !harge !annot beguessed a!!ording to the !harge in distilled %ater in the inorgani! laboratory. It has to bedeter#ined e<peri#entally and !annot be !lassified a!!ording to the ioni! rule in a+ueous

solution but is #ostly dependent upon the lyophile S!olloid %ith strong, %ea*, or la!*inglyophile-sol$able !apa!ity8 series of 'of#eister and piro first published in 1:9)8. This seriesin!ludes the positi$e half of both a!ids and al*alis, represented by lithiu# and sodiu#, !al!iu#,



iodine as one group, and the ele!tronegati$e half of the series, !hara!terized by potassiu#, phosphate, !itrate, sulphate as the other group. These t%o groups in plants and ani#als %ere*no%n, by bio!he#ists, #ore than one hundred years ago. The t%o antagonisti! groups ha$ealso been !alled e<tra!ellular and intra!ellular, a #isleading designation. The thyroid is anele!tronegati$e !enter or !athode of the body, $ery s#all, and therefore %ith a s#all a#perage,

but %ith a high $oltage in the !olloid. Table I of this !hapter sho%s that the Aa is deposited and

a!!u#ulated in the thyroid. Therefore, %e ha$e to !onsider that the so-!alled e<tra!ellular Aa#ust, in this instan!e, be intra!ellular. It should be e#phasized that the %hole positi$e half ofthe lyophile series CA, I, r, Aa, Ca, Cl, s , ?, l8 is a!!u#ulated in the thyroid. It is foundele!tronegati$e as a redo< potential in the !olloid, its #ain #ass, by >e6obertis and Gonzales19;48 and by all earlier in$estigators. The thio!yanate CA8 %as al%ays found biologi!ally#ore positi$e than the iodine. The !lini!al signifi!an!e is that thio-!yanates and other!o#pounds of si#ilar !onstitution plus thiour-a!il not yet e<a#ined8, sulfa drugs, andsali!ylates ha$e a tenden!y to repla!e iodine. Therefore, iodine appears to be a $ery #obile and$ulnerable substan!e in the thyroid as de#onstrated by its easy repla!eability in biology8.The se!ond ele#ent in the positi$e half of the lyophile series is the iodine. There is no doubt

that the iodine is attra!ted %ith parti!ular for!e by the nor#al thyroid, but less so in hypo- as

%ell as hyperthyroidis#. In both, the iodine !ontent is de!reased in the thyroid, inhyperthyroidis# e$en up to l1th of the nor#al. The differen!e is that blood iodine is #ar*edlyele$ated in #ost !ases of hyperthyroidis# %hile it is de!reased in hypothyroidis#. notherele#ent, %hi!h is $ery near to the positi$e head of the series is ionized !al!iu#. Cal!iu# %asal%ays found greatly a!!u#ulated in the thyroid by bio!he#i! essay and by nii!roeherai!alin!ineration. !!ording to the te<tboo* on bio!he#istry by /ppenhei#er, ron and Gral*a,nearly 1 #g#. per !ent %as present in 1 gra#s %hi!h #eans rather #ore in #ols than thenor#al thyroid stores I plus Aa. Then follo%s bro#ine, %hi!h Tanino has found in thyroids of!orpses of hospital patients to be a!!u#ulated in t%entyfold a#ount of iodine, if the patients hadre!ei$ed bromides during their disease. The bro#ine !ontent of the thyroid is a #a<i#u# in!o#parison to other organs %ith one e<!eption the %all of the aorta. The loss of iodine and its$arious effe!ts on the entire ner$ous syste# should be seriously !onsidered %hene$er bro#idetherapy is used !lini!ally.

There re#ain fluorine and arseni!, %hi!h ha$e their #a<i#u# a!!u#ulation in the thyroid ona!!ount of their biologi!al ele!tro-positi$ity. This #a<i#u# refers to the protoplas#i! organ or

paren!hy#al !ells, not to the solid !rystallized stru!tures su!h as hairs, bones and nails. The bones, for e<a#ple, ha$e a thousand ti#es #ore !al!iu# than the thyroid, but a#ong ; other*inds of protoplas#i! stru!tures, calcium is found at its #a<i#u# in the thyroid and a!ti$atedor ionized there.

!!ording to the anlyses of the al*ali #etals, found deposited in the thyroid, %e #ay!on!lude that the thyroid as a %hole is relati$ely ele!tronegati$e and that the !olloid in its

folli!les 4 per !ent in nor#al thyroid8 has a rather high negati$e $oltage. The !ontents of theother ele#ents or radi!als, a!!ording to the abo$e-+uoted earlier publi!ations, !onfir# thisthesis or, at least, do not !ontradi!t it.

If the thyroid is the strongest ele!tronegati$e !enter of the body, a!!ording to others and ouro%n findings, %e ha$e to dis!uss so#e !onse+uen!es for the !lini!. The other organs %hi!hsee# to !o#e $ery near to the great negati$ity of the thyroid are the bile !apillaries and the

pan!reas 3angerhans islands.The li$er proper is supposed to be the !hief positi$e !enter of the organis# in relation to

ele!trostati! theory. Aot on a!!ount of the ele!tronegati$ity of the bile !apillaries, but fro##erely pra!ti!al e<perien!e, I ha$e gi$en bile preparations for #any years to %ea* or !a!he!ti!

patients %ith !hroni! debilitating diseases. 3ater, I #ay try to apply the bile #edi!ation to this

theory as it produ!ed in the #a5ority of the !ases a benefi!ial effe!t, %hate$er the reason for it%as. In !an!er there #ay be a gradual loss be!ause of less ability to be reabsorbed.

The other organs %hi!h are also predo#inantly negati$ely !hargedRthe spleen, the s*in and



the !onne!ti$e tissueR!ontain proportionately #ore iodine, sodiu#, bro#ine, et!., and the other#e#bers of the lyophile series are i#portant for therapeuti!s in this respe!t. The ne<t neighborto iodine in the lyophile series is bro#ine, %hi!h is only 1 or 1) #illi$olts less biologi!ally

positi$e than iodine.

"hat happens, for e<a#ple, to the thyroid, if bro#ides are ad#inistered ?. Tanino tried toans%er this +uestion. 'e analyzed the thyroids of !orpses of hospital patients ti#e and dosage

are not reported8 after the ad#inistration of bro#ides. =ost of the old people %ere +uitee#a!iated, had lost the iodine of the thyroid for the greater part and had a!!u#ulated bro#ideinstead. I list here a fe% figures of Table II of Tanino %hi!h gi$es the results of thyroids, #oist

glands, %ith #ediu# !olloid !ontent.table

Se Age# disease mg Br mg I Br*I normally

)*+-

fe#ale (( Tuber!ulosis 1:.; (.4 7.=ale 77 =yo!ardia ).; (.- 1.

=ale ): 2neu#onia (.7 1.; 14.4=ale ;( Aephros!lerosis 9. 1.; (7.C

In thyroid, bro#ine is nor#ally 1 #g#. per !ent or a little #ore 3abat8. The nor#al thyroid!ontains in #oist glands . to .4 per !ent iodine.17

The figures sho% a tre#endous loss of iodine, in so#e !ases redu!ed to a #ini#u# fro# ana$erage of ;) #g#. per !ent to 1.; #g#. per !ent. These signifi!ant !lini!al findings, i#portantfor !lini!al bro#ine therapy, are generally o$erloo*ed. s for an e<planation, it #ay be statedthat the #ass a!tion la% of Goldberg and "aage 1:)(8 has a strong effe!t in the e<!hange of

bro#ine for iodine. The nor#al blood seru# has the relation of 11 of bro#ine to iodine,

about one #g#. and not ga#as li*e iodine. s early as 191, 3abat had dis!o$ered that nor#alani#als a!!u#ulate the largest store of bro#ine in the thyroid.

The study of Tanino&s figures, %hi!h sho% in all other !ases the sa#e tenden!ies #ore or less,raises so#e ne% proble#s. If %e re#e#ber that bro#ine #edi!ation #ay produ!e a !hara!-teristi! e!ze#a and al#ost the sa#e rash is obser$ed by other neighbors of the lyophile series,%e as* oursel$es %hether the

*1/ oll#ann, Pharmacology, p. 97.

s*in affli!tion, !alled bro#ine or thio!yanate e!ze#a,1: #ay not be partly a result of iodinedefi!ien!y. /r %e #ay !onsider %hether the so#nolen!e or rather an iodine defi!ien!y is present.s a #atter of fa!t the other neighbors in the 'of#eister-piro series produ!e a si#ilar tenden!yto sleep. fter %e had found that the thyroid is a store of Aa, r, I, and other #inerals of theele!tropositi$e and lyophile series %hi!h tra$el in the biologi!al #ilieu to the !athode, %e %ereinterested in the e<a#inations of . E. 6appaport, %ho e<a#ined #any body organs in theiral*alinity or a!idity e<pressed in p'. 'e e<a#ined the !orpses of hospital patients hours aftertheir death and still found strong differen!es in a!idity. The highest al*alinity in the thyroid %asusually one and a half units of p' higher than the brain e+ui$alent to 7: #illi$olts8. "e ha$e tore#e#ber that the brain is one of the !ounterparts of the thyroid !he#i!ally as %ell asele!tri!ally and that it has re!orded the #ini#u# in iodine and other substan!es of the positi$ehalf of the lyophile series %hile the thyroid has the #a<i#u# !ontent. The !erebru#, so stronglyinfluen!ed by tra!es of iodine, has only a #ini#u# of iodine in its o%n substan!e on

?ellenberg8.The p' of thyroid and brain is, a!!ording to 6appaport

Thyroid Brain



al#ost e$ery tu#or is surrounded by su!h tissue, and the sa#e tissue also e#bra!es all ne%!an!er establish#ents. This !onne!ti$e tissue is al#ost ina!ti$e and paralyzed in !an!er,in!apable of helping or prote!ting the body any longer in defense or healing.

nu#ber of s!ientists ha$e tried $arious #ethods to sti#ulate the reti!ular syste# as %ell asthe reti!ulo-endothelial syste#, %hi!h see# to !ontrol and regulate the gro%th of !ells. ?ailureof these syste#s #ay !ause the un!ontrolled gro%th, %hi!h is a !hara!teristi! part of !an!er.

I ha$e found that this i#portant syste# !annot fun!tion suffi!iently and satisfa!torily be!ausethe entire body is poisoned and has lost part of the ionized #inerals of the P-group and si#ul-taneously so#e of the ele!tri!al potentials, et!. =any s!ientists regard these syste#s as part ofthe healing apparatus.

2rofessor G. $on erg#ann des!ribed this #ethod of !an!er de$elop#ent by %ritingtranslated8 Can!er #etabolis# ta*es pla!e on!e the body is no longer !apable of produ!ing ana!ti$e &infla##ation #etabolis#& ... the !an!erous organis# is anergi! in respe!t toinfla##ation.; The e<peri#ents of his assistants, 6uth 3oh#ann and 2es!hel de#onstrated, asrefle!ted in the follo%ing tables, that !an!er !ells !an be *illed in fluid fro# a

11( 5p. tit., 19), pp. 14, 117.11 ee Gan:heitsbehandlung der Geschwtilsterkrankungen Totality Treat#ent of Tu#or >iseases8

edited by 2rof. "erner Mabel. tuttgart, 19).11; ee $on erg#ann&s ?un!tionelle Pathologie, Lulius pringer, erlin, 19(, p. '>+#

nor#al infla##ation #etabolis#, not in blood seru#. This indi!ates the fa!t anor#al body !an *ill !an!er by produ!ing an infla##ation.

The papers of ?riedri!h Pauf#an on non-ba!terial infla##ation re$ealed that these

infla##ations are follo%ed by #esen!hy#al infla##atory rea!tions of genuine nature, %ith!apillary a!ti$ity, !ell a!ti$ation and loss of %hite blood !ells. In the sa#e ani#als, !hanges inthe li$er %ere found at the sa#e ti#e, on the epithelian paren!hy#, in !onne!tion %ith the fi$er!ells the#sel$es as %ell as by infla##atory rea!tions on the #esen!hy#al tissue.

fe% of #y o%n e<peri#ents %ith !antharidin plasters ha$e !onfir#ed the fa!t that !an!er patients !ould not produ!e an infla##atory rea!tion after irritation by !antharidin !he#i!al. Theonly e<!eption %as a !ase of beginning s*in !ar!ino#a, %hi!h produ!ed about a third of thenor#al rea!tionO but the blister fluid !ould no longer *ill !an!er !ells. fter se$eral #onths orlonger of deto<i!ation, diet and #edi!ation, patients sho%ing fa$orable response %ere able to

produ!e a nor#al infla##ation #etabolis#, !apable of *illing !an!er !ells. In this !ountry, I %as11) 5p. cit., p. '>*#11: 5p. at., p. '>'#

not in a position %here I !ould !arry out enough e<peri#ents to !onstitute a s!ientifi! proof ofthe fa!t that general deto<i!ation and restoration of the #etabolis# are basi! parts of the



healing of !an!er.G. $on erg#ann %idens the !on!eption of infla##ation as an allergi! rea!tion by %riting

The si!*nesses %hi!h are in our do!trine of diseases separated a!!ording to the different organsha$e !o##on biologi!al rea!tions %ith !ellular pro!edures surpassing the defense of thereti!uloendothelial apparatus. In!luded in the allergi! rea!ting organs are the diseases of thesto#a!h as %ell as the !olon, the great glandular paren!hy#atous organs of the li$er, pan!reas,

#eninges, endo!ard, peri!ard, syno$ia of the 5ointsRfinally the #us!les, not the least being theheart #us!le, in parti!ular the $essels, the arterioles, $enules as %ell as the !apillariesRall ofthe# rea!ting %ith in$isible biologi!al stru!tural !hanges of the !ells and tissues and in the &hu#ural!ondition.& I **/

The theory of the fun!tional part of the diseases $on erg#ann !alls pathology of thefun!tion, %hi!h !an lead in both dire!tions either to the ad$antage or disad$antage of the or-ganis#. Ao% %e !o#e to the !ore of the proble# as to %hether %e !an influen!e these biologi!al or

allergi! rea!tions, and ho% far and in %hat #anner one !an dire!t the#.The !an!erous body presents in general an anergi!, rea!tion as far as the !an!er #ass and its

#etaboli! poisons are !on!erned. Therefore, in #ore ad$an!ed !ases, light infe!tions #ay be

fatal. ll atte#pts to sti#ulate the syste# by $irulent s*in infe!tions or !o#binations of theirto<ins to an allergi! response against the !an!er !onsistently failed.

3ater the unspe!ifi! allergi! rea!tions be!a#e !lini!ally #ore i#portant sy#pto#s regarding the progress of the do!trine of the infla##ation. ?irst $on 2ir+uet and later !hi!* studied theinternal infla##atory !onditions #ore intensely.

It %as found that the cantharidin blister fluid !an be used as a #easure#ent indi!ating thedegree of infla##atory preparedness !alled allergy8 of the total body, its $ariability during the!ourse of the infe!tions and other noninfe!tious diseases, and, I %ould li*e to add, for the!onfir#ation of the healing in !hroni!

117 5p. cit., p. 144.

diseases and !an!er although not enough e<peri#ents ha$e been !arried out to date.

The de!isi$e step for%ard !a#e %hen the erlin pathologist, 2rofessor 6oessle, published hise<peri#ents. 'e sho%ed that guinea pigs rea!ted %ith different types of %hite blood !ellsdisappearing fro# the irritating !apillaries by the sa#e sti#ulus but after different *inds of

pre$ious treat#ents %ere applied to the ani#als in using in5e!tions of $arious protein solutions./n su!h a basis, #ore and #ore authors !a#e to the !on!lusion that the body and its present

state of infla##atory preparedness de!ide the degree and type of infla##atory-rea!tion, not thedegree or type of the applied sti#ulus. 3i*e%ise, ir!ho%&s !ellular pathology is no longer $alidin this respe!t, but the predo#inant fun!tions of the !ells and their !hanges are effe!ti$e. The

sa#e dis!o$ery %as #ade in the field of tuber!ulosis by P. E. 6an*e %hen he stated that not the$irulen!e nor the a#ount of tuber!ulosis ba!illi deter#ine %hether there %ill be an e<udati$e or produ!ti$e type of lung tuber!ulosis, but rather the !hara!ter of the rea!tion of the organis#against the sti#ulus is de!isi$e. The re!ipro!al effe!t bet%een reagens and rea!tor !an be sogreat that any !o##on $irulent strepto!o!!us sto!*, for e<a#ple, !an be !hanged to a %ea*ertype su!h as strepto!o!!us $iridans %hi!h o!!urs in sepsis lenta older obser$ations8.

To see the ad$antages of the allergi! infla##ation %e ha$e to loo* into the anato#i!al and biologi!al findings of this fun!tion. This sub5e!t is des!ribed at length in #y tuber!ulosis boo*,11: %hi!h also in!ludes an e<planation of the rthus pheno#enon in li#iting the spot andsa$ing the body.

"e learn fro# pathologi!al and e<peri#ental findings that in !an!er there is no suffi!ient

blo!*ade around the tu#or. The %ay is free for ne% settle#ents to spread and thus poison the body and *eep it under its destru!ti$e rule. The degree of the barrier and the !apa!ity of theeli#ination organs, parti!ularly the li$er, deter#ine the progress of poisoning and brea*do%n of



the body, %hile the defense apparatus be!o#es #ore and #ore ina!ti$e.

11: Gerson, =a<, =.>. Dietary Therapy of ung Tuberculosis, pp. 1):, 14), 144, pursuant to the testsof 6oessle %ith respe!t to the rea!tion pro!eedings In the allergi! tissues.

The fa!t that %e regard the body in its entirety should not lead us to assu#e that the tu#or, theglands and the #etastases !an be influen!ed at one ti#e or e$en !ured all together. The !on!eptof totality should not let us forget that ea!h si!* organ, e$en ea!h node and gland, has its o%n

pathologi!al anato#i!al !onditions, on %hi!h the #ethod of healing essentially depends./steolyti! and osteoplasti! pro!esses !an e<ist in the sa#e organ or e$en in the sa#e $ertebranearby and it appears that ea!h single spot, node, tu#or or destru!ti$e pro!ess has so#e biologi-!al la%sO despite this, it re#ains the tas* of the treat#ent to subordinate all the pathologi!al andhealthy organs, tissues, and !ells for the benefit of the %hole. This is the natural %ay for the#etabolis# to be supported by the autono#ous ner$ous syste# %ith the reti!ulo and reti!ulo-endothelial syste#. The !lose !ooperation of the li$er is essential.

e!ause of the !ontinuous failures in the e<tensi$e e<peri#ental resear!h, #ost of the authorsare unsu!!essful in sol$ing the !an!er proble#. In #y opinion, pri#arily be!ause !o#prehension

of the deto<i!ation has al%ays been o$erloo*ed in !lini!s, %e are not suffi!iently trained in thatdire!tion. In addition %e ha$e to ta*e into a!!ount that %e ha$e $ery little or transient orsy#pto#ati! results in other !hroni! diseases. fter su!h e<perien!es, it is $ery diffi!ult for the

physi!ian to a!!ept the idea that a !an!er patient !an be !o#pletely restored. G. $on erg-#ann%rote syste#ati! therapeutic de$elop#ent of this theory #ay not be possible, . . .119. This#eans that he, as #ost other authors, ne$er e<pe!ted that it #ight be possible to restore#etabolis# in a !an!erous organis# to an e<tent suffi!ient for healing purposes.

I repeat The !an!erous body is anergi!, %hi!h #eans that it !annot pre$ent !an!erous gro%thnor respond and defend itself against it. The treat#ent, therefore, has the tas* of restoring thesenor#al fun!tions so that the defense apparatus, li$er %ith reti!ulo and reti!ulo-endothelialsyste# !an fun!tion and that finally, the !onditions are restored for produ!tion, a!ti$ation and

rea!ti$ation of o<idizing enzy#es."e ha$e $ery often seen, in the #ore ad$an!ed !an!er !ases, that there are only a fe%

ly#pho!ytes on the a$erage -1 in

119 $on erg#aan, 7unctionelle Pathologie,

the so-!alled differential !ount8. This sho%s that the body is no longer !apable of produ!ing thene!essary a#ount of ly#pho!ytes for its nor#al need or for its healing po%er. "e see not onlyin !an!er, but also in other !hroni! diseases, that the body has lost the a!ti$ity of the $aluableand ne!essary #other-tissue of ly#pho!ytes. If %e follo% the suggestions of so#e authors, %e#ay assu#e that the reti!ular and the reti!ulo-endothelial syste#s both are the ter#inals of the

$is!eral ner$ous syste#. These authors also thin* that the fun!tions of our internal organsdepend, to a greater degree, on the fun!tions of that autono#ous syste#. 2rofessor 2is!hingerre#inds us in his arti!le that these tissues also play a !entral role in the budget of the o<ygen,thus helping to bring o<ygen into the !ells. ?ro# 2rofessor !hade&s %or* %e *no% that the!onne!ti$e tissue is interposed bet%een the !apillary and the epithelial !ell, or any other !ell, inthe body. If %e assu#e that the $is!eral ner$ous syste#, the reti!uloendothelial syste#, theinterposed !onne!ti$e tissue and, on the other hand, the rea!ti$ation also of the o<idizing enzy#esis #ore or less da#aged in the !an!er body, %e #ay understand that so#e abnor#al !ells arefor!ed to go o$er fro# the use of o<ygen to the use of fer#entation, %hi!h !hanges the life!onditions of these !ells and their gro%th and penetrates the surrounding tissue to the greatestdegree.

In all e<peri#ents e<!ept for one %hi!h !ould not be !onfir#ed, it %as found that !an!er !ells!annot be sti#ulated or for!ed to !hange their abnor#al fun!tions ba!* to nor#al ones. There isno other %ay but to *ill these !ells to dissol$e and absorb the#. I belie$e the surest %ay to



'ospital, >epart#ent of 2athology, Chi!ago, ino!ulated an e<tra!t of hu#an !an!er into patientsaffe!ted %ith !an!er. The ai# of that !lini!al trial %as to find %hat therapeuti! effe!t su!h treat-#ents ha$e. fter in5e!tions, !hill and te#perature lasted for t%o hours and #ore. The results%ere a #ar*ed in!rease in appetite, #ore strength, and a slight in!rease in %eight. The ly#phnodes di#inished and be!a#e #u!h harder. Ao !ure %as obtainedRonly te#poraryi#pro$e#ent.

>r. ?ehleisen 1::, erlin Charite8 ino!ulated real erysipelas infe!tion into !an!erous areas.This resulted in #any failures and a fe% re#ar*able su!!esses. G. $on erg#ann thin*s thate$ery e<perien!ed !lini!ian *no%s of a fe% !ar!ino#as !ured by inter$ening infla##atory

pro!esses.'98 Iid.1(1 ee Gon:heitsbehandlung der Geschwulsterkrankungen.

>r. "illia# . Coley, Ae% For* 1:918, de$oted his life to this dra#ati! treat#ent %itherysipelas ino!ulations, later %ith pyogeni! #i<tures su!h as strepto!o!!us, staphylo!o!!us and

pyo!yaneus, still later adding ba!illus prodigiosus. Coley&s results and those of others re#ained

+uite un!ertain and sparing. The great #a5ority of the #edi!al profession re#ained $erys*epti!al about this #ethod of !an!er treat#ent.

The idea of helping the !an!erous organis# through a strong infla##ation is old but %as!orre!t fro# the beginning. The proble# is to find the surest and #ost effe!ti$e %ay to do this.

Can!er patients ha$e different types of allergi! rea!tions. o#e patients %ith 'odg*in&s diseaseresponded %ith al!ohol-indu!ed pain due to #alignan!y.1(( The pain %as regarded as an allergi!rea!tion brought about by a !ar!ino#a, as it %as not [ present before the disease. The patient hadapparently enough po%er for an allergi! rea!tion but not enough for an allergi!infla##ationRnot intensi$e and a!ti$e enough for an allergi! infla##ation %hi!h is thede!isi$e part of the body&s %eapon of healing po%er. Conse+uently, it appears that there #ust

be a !hara!teristi! differen!e bet%een allergi! rea!tions and allergi! infla##ations, sin!e bothare not +uite separated in their li#itation and !ausation. t the beginning of the !an!er %e !anassu#e that %ith the allergi! rea!tion there is still a part of an allergi! infla##ation present andeffe!ti$e, too %ea*, of !ourse, for healing po%er, but to a !ertain degree suffi!ient to restri!t thetu#or and to *eep it te#porarily lo!alized. It is reported in the sa#e arti!le that the patient %ithallergi! rea!tion to al!ohol ( #l.8 had only a slight dis!o#fort !aused by the allergi! rea!tionto al!ohol %hen the roentgenogra# sho%ed that the tu#or %as larger and better defined. 3ater,the anergia in!reased %hen the tu#or gre% faster, and there %as no longer pain after drin*ingthe +uadruple a#ount of gin : #l.8. u!h obser$ation indi!ates #ost probably that the in!reaseof into<i!ation de!reases gradually the allergi! rea!tion to nil. These and other obser$ations aresignifi!ant signs of the redu!tion of allergi! rea!tions by progressing into<i!ation i##inent in a

!an!erous body. <t therefore appears that the bodyJs capacity to produce++ ee L..=.., =ay 1:, 19)7, ol. 14;, Ao. , p. .

an allergic inflammation Khealing power3 depends on a most complete detoxication and an

e2uilibrium in the metabolism to near normal.

The healing apparatus see#s to ha$e retained part of its e#bryoni! !apa!ity and healing purpose for a type of regeneration,1( %hen it falls ba!* into the e#bryoni! state te#porarily andis a!ti$ated abo$e the degree of its nor#al fun!tion.

The !o#pletely deto<ified body is then able to produ!e an allergi! infla##ation if the healingapparatus Sli$er, $is!eral ner$ous syste# and reti!ulo-#esen!hy#al syste#8 !an be a!ti$atedsuffi!iently. E$erything that !an help to bring it about and strengthen the ne!essary allergi!infla##ation #ay be used for that purpose after the general deto<i!ation has ta*en pla!e,a!terial preparations Coley and others8 or 2yrifer, or any si#ilar preparations are effe!ti$e, as



far as they !an sti#ulate the $is!eral ner$ous syste# in !onne!tion %ith the li$er and the#esen!hy#al defense and healing apparatus. "e ha$e to bear in #ind that there are $erydifferent rea!tions a!!ording to the state and energy-!apa!ity of the healing apparatus. It #ay bead$isable to sti#ulate, in addition to #y treat#ent, the liberated $is!eral ner$ous syste# and thereti!ulo-endothe&ial apparatus %ith a #easured ba!terial reagens. 'o%e$er, I ha$e had no e<peri-en!e %ith it. "e do not *no% %hat sti#ulus a!ts first and %hat tissue should be a!ti$ated. G. $on

erg#ann p. 1718 +uotes the des!ription of the !ourse of the infla##ation fro# an arti!le byPe#pner translated8 t any sti#ulus an e<udation and i##igration of %hite blood !ells setsin. The !he#i!al !o#position of the e<udate is the sa#e as that of the seru# in the beginning8.s soon as the e<udate and the infla##atory !ells are present, there starts an o%n life separatedfro# nor#al tissue %ithin the infla##ation area, in the !enter of %hi!h is the #etabolis# of theinfla##atory !ells. The $elo!ity of the infla##atory rea!tions depends upon the presen!e ofinfla##ation !ells. These !ells ha$e an o<idati$e and digesti$e #etabolis# and by #eans of tin&s#etabolis# !ause an a!idosis of the infla#ed tissue and redu!tion of the infla#ed spa!e ofo<ygen and energy-produ!ing substan!e sugar8. !id for#ation and defi!it of energy-

produ!ing substan!e

1( George ". Crile, 4ipolar Theory of iving Processes. =a!=illan Co.,19(4, p. 144

bring about da#age or destru!tion of infla#ed tissue, a *ind of s%elling, degeneration andne!rosis.1(;

fter the infla##ation has *illed the tu#or #ass, see Tables I and II, this !hapter8 ne!rosissets in. In ne!rosis of !ir!u#s!ribed lo!alized areas the i#portant fun!tion is the digesti$e po%erof leu*o!yti! enzy#es of fibrin and debris in infla#ed areas, for indigested fibrin a!ts as aforeign body and leads to fibrosis. The ter# ne!rosis is used to des!ribe the !hanges %hi!h the

dead tissue and !ells undergo after their death. The ter# ne!robiosis is used in referen!e to the physiologi! death and repla!e#ent of !ertain !ells %hi!h are !onstantly o!!urring, e.g., blood!ells and in epider#is.1

=y o%n obser$ations ha$e sho%n that far ad$an!ed !an!er patients ha$e lost their allergi!#igraine rea!tion and other *inds of allergi! rea!tions. >uring the healing ti#e the #igrainesy#pto#s re!ur partially but disappear %hen the patient is !ured entirely, as the !o#bineddietary regi#e is enough to !ure allergi! #igraine sy#pto#s in #ost !ases %ithout !o#bination%ith !an!erO I also #ade si#ilar obser$ations %ith other allergi! #anifestations. In all theseinstan!es it %as found that the degree of allergi! rea!tions $aries in$ersely %ith the degree and

period of shorter or longer lasting into<i!ations. Can!er patients %ith allergi! syndro#es arefor!ed to #aintain part of the diet %ithout salt and %ith lo% ani#al fats and proteins for #any

years.I do not belie$e that there is funda#entally #ore than one healing apparatus in the body.

trong said 19;8 @p to the present there is not yet one !an!er atta!*ing defense-#e!hanis#re$ealed.

The treat#ent is, of !ourse, unspe!ifi!. To re5e!t any dietary regi#e be!ause of insuffi!ient physiologi!al proof is not sound.0(

/n the s*in %here %e had been able to study the healing of lupus see #y Tuber!ulosis boo*, p. (8 %e !ould also obser$e the follo%ing in !an!er fter the body is deto<ified, infla##ation%ith redness and slight s%elling of the in$ol$ed spot starts. fe% days later the redu!tion of theede#a and infiltration sets in. The abnor#al spot and the se!ondary infe!tions %ill be dissol$ed

by the digesti$e enzy#es and finally absorbed into the blood

1(; $on erg#ann, 7unctionelle Pathologie, p. 171.1() ". . >. ndersen, Pathology, p. 9).1(4 P. '. auer, >as @rebsproblem, pp. 4)-47.



strea#. @nder the #i!ros!ope, %e see the !reation of ne% !apillaries %hi!h penetrate into theinfiltrate and the ne!roti! #ass and build the so-!alled granulation tissue.They se!rete all different hor#ones and probably also enzy#es, si#ilar to the pla!enta tissue in

!ooperation %ith the o<idation pro!esses it is the fun!tion of leu*o!ytes, ly#pho!ytes, histio-!ytes8. The healing pro!ess starts %ith hypere#ia and then the different stages of reabsorption

follo%. The blood pi!tures sho% at that ti#e an in!rease in leu*o!ytes and ly#pho!ytes and as#all in!rease in #ono!ytes. >uring the healing ti#e a s#all in!rease in lipase %as !onfir#ed, ane!essary de$elop#ent for the digestion of the fatty !ell frag#ents. t the beginning of thedietary regi#e, %e sa% and learned that so#e nutrients hinder the healing pro!ess, %hereasothers further it. These obser$ations %ere used as indi!ators to point out %hat substan!esda#age or %hi!h other ones are ne!essary for the healing pro!ess in that period.

>espite the obser$ation that %e !an see the healing pro!esses in s*in !an!er under the#i!ros!ope, the fa!t re#ains that %e do not *no% e<a!tly the organ or organs %hi!h ha$e to besti#ulated and %e do not *no% %hat part of the treat#ent a!ti$ates the#.

"e do know that a healing apparatus is present and functions in a healthy bodyEand we

learned, in addition, by means of this treatment that it can be reactivated if the body can be

sufficiently detoxified 8in degenerative diseases and cancer3."e ha$e the distin!t i#pression that the internal organs present si#ilar or e+ual situations

under treat#ent %hi!h the s*in !an!er refle!ts. The N-rays pro$e it on the bones, lungs and otherorgans.

>eep rea!hing !an!erous ul!erations need se$eral !orresponding infla##ations so-!alledflare-ups8 until the larger area is !o$ered %ith #ore granulation tissue or ne% s*in.

These flare-ups !o#e at inter$als and %ith so#e %o#en 5ust before their #enstruation.

=y idea is that the deto<i!ation obtained by fre+uent ene#as, by the dietary regi#e and so#e#edi!ation pa$e the %ay for the first allergi! healing infla##ationO the body #ust be#aintained deto<ified and in a #etaboli! e+uilibriu# e$en %ith a partially fun!tioning li$er forthe follo%ing flare-ups.

"e should not forget that after the *illing of the tu#or #ass and its dissolution, the absorption,until re!o$ery is a !onstant hea$y burden on the eli#ination apparatus, in parti!ular on the li$erand *idneys. If %e do not help the patient intensi$ely day and night to eli#inate these additional

poisonous substan!es, as I ha$e seen it at the beginning of this treat#ent, there is a seriousdanger that the patient #ay fall into a hepati! !o#a.

In the first t%o %ee*s of this treat#ent %e obser$e that the patient a%a*es fro# the half!o#atous #ood, !aused partly by a pre$ious high sedation therapy and partly by the to<ins fro#the gro%ing tu#or #asses a!!u#ulated and no% a!ti$ated in the body. In the first ten days theurine sho%s #u!h eli#ination of AaCl, up to eight gra#s per day, rarely ten gra#s. !etone

plus t%o to three, disappears in about one %ee*, often together %ith a tra!e of albu#in andhyaline !asts.

The red blood pi!ture re!o$ers steadily in four to si< %ee*sO the %hite differential !ount sho%sthat its produ!tion apparatus has to !arry the burden.

"ithin a fe% days all %hite !ells ha$e to<i! granules, the ly#pho!ytes in!rease slo%ly, thenu#ber of leu*o!ytes re#ains in!reased for a fe% %ee*s also the per!entage of neutrophiles. "elearned that the stronger the deto<i!ation, the +ui!*er and #ore surprising are the results, as longas %e are able to *eep the #etabolis# free of poison and e+ualized in #any respe!ts despite thefa!t that %e ha$e to handle other hea$ily da#aged or e$en partly destroyed organs.

In this %ay it is possible to bring the !an!er-#ass or #asses out of their partial se!lusions orhiding pla!es ba!* into the e<!hange of the general #etabolis#, into its support and regulation.'o%e$er, the deto<i!ation is only a part of the healing pro!ess though an i#portant part.i#ultaneously, the #etabolis# has to be balan!ed at least to a !ertain degree. The si!* organsare unable to do so the#sel$es for a long period, espe!ially in ad$an!ed !ases.



The body needs essentially the i#portant #inerals P., I., 2.8, the o<idizing enzy#es and!oenzy#es, and the hor#ones.

ll of the# #ust be!o#e a!ti$ated in the body and #ust be re-a!ti$ated there, other%ise theyare lost. E+ually i#portant is the restoration of the p' #inerals in the !ells8 so that the enzy#es!an fun!tion again step by step.

$ll the explanations in this book about the healing of cancer as well as other presentations

would be not much more than words, if we were not able to demonstrate the correspondingclinical facts of real healings. 4ut after these facts are achieved, these conceptions are

explanations for our clinical observations.

/ur #odern !i$ilization has brought about su!h %idespread !hanges in our nutrition that so#e!an!er authors spea* about a so-!alled pre-!an!erous !ondition. I feel it #ust be e<pressed #oregenerally as a ryre9morbid pathology. ?or our tas* it is i#portant to *no% that %e ha$e nolonger a natural nutritionO therefore, the therapy is #ore diffi!ult. The pre-stages probably !ould

be re!ognized by e<a#ination of P, I, urea-A and uri! a!id, and !ould be #ore easily restored.The !an!erous tissues, ho%e$er, #ust be *illed, sin!e after their #i!roso#ata and #ito!hondriatoo* in !ertain bio!he#i!al !hanges in #inerals and ele!tri!al potentials and probably also

parti!les of a ne% protein substan!e into their !ell for#ation, they !annot be retransfor#ed tonor#al.

?inally, healing of !an!er #eans the restoration of the entire #etabolis# %ith its enteral and parenteral digestion together %ith its defense and healing fun!tions.

E<tirpation of !an!er gro%ths does not #ean a !ure of the disease. The i#pro$e#ent %hi!hfre+uently follo%s an operation #ay sho% that the liberation of the body fro# su!h poison-

produ!ing #ass is a great help for the syste#, and points to the dire!tion that the partialdeto<i!ation of the body benefits the !an!er-bearing syste# at least to a !ertain degree, andte#porarily. The i#pro$e#ent see#s to be only in the beginning, after the operation and inlo!alized !ases only, but this is not suffi!ient for the produ!tion of an allergi! infla##ation. Inthe literature, the allergi! or healing infla##ation is referred to as !hanges in the en$iron#ental

!onditions. This is an in!orre!t !on!eption.

C-APT1B =.III

Role of Allergy in the -ealing Process of Cancer

IT EE= !ertain that the healing po%er in !an!er has to be introdu!ed by an allergi! rea!tion. Tounderstand this healing po%er, one #ust ha$e a brief e<planation of the proble# of allergy itself.>r. $on 2ir+uet had e<plained allergy as a !hange in tissue rea!tions. This #eans ahypersensiti$ity de$eloped in the body !aused by an infe!tion or after in5e!tion of a proteinallergen8. nergy is the !ontraryO it refers to a di#inished or la!* of rea!tion against an antigen.'. '. >ale e<pressed the allergi! rea!tion and !onse+uent fun!tion as follo%s !hange in thedispersity of protoplas#a !olloids o!!urs if the prae!ipitin fi<ed in the !ell protoplas#aen!ounters the antigen onto %hi!h it has a spe!ifi! affinity. !hange in the dispersity of the

protoplas#a !olloids sets in, %hi!h indu!es an enzy#ati! dissolution, and the produ!tion ofhista#ine-li*e substan!e or hista#ine itself.1(7 The rea!ting organs at the allergi! atta!* are

parti!ularly the unstriped #us!les and the !apillary endothel, both of %hi!h stay under theregulation of the auto#ati! ner$ous syste# and endo!rine apparatus.1(:

"hen the tu#or #asses are in pro!ess of dissolution, there is a greater a#ount of highly a!ti$e

protein9intermediary substances su!h as hista#ine, histidine, et!., %hi!h !an a!ti$ate different pathologi!al rea!tions all o$er the body. These !ountera!t the

1(7 ee 4ulletin, Bohns 'op*ins 'ospital, 1, 11, 19(.



1(: ee rthur ?. Co!a, 7amilial "onreaginic 7ood !llergy, 9nd edition" '(*)" Charles C Tho#as,pringfield, Illinois.

healing po%er. To neutralize and eli#inate the# is the tas* of the therapy.#all +uantities of indole, s*atole and phenol are absorbed into the bloodstrea#, undergo

deto<i!ation in the li$er by !on5ugation %ith sulphuri! a!id and potassiu# or %ith gly!uroni!

a!id."hat really happens in the body in allergi! rea!tions or stronger in anaphyla!ti! sho!*s is that

nor#al enzy#ati! pro!esses are redu!ed.1(9 This idea is based on the follo%ing findingsbderhalden and "erthei#er found redu!ed a#ount of tissue, gas-e<!hange and less o<idationO3oehr found di#inished digestion of aro#ati! proteinsO 'ashi#oto and 2i!* found pathologi!al

proteolyti! pro!esses parti!ularly in the li$er !ells. in!e these rea!tions o!!ur in different organsand tissues, . ?. Co!a !alls the# spe!ies spe!ifi! sho!*organs or sho!*tissues.

The *ind of allergen sti#ulant does not deter#ine the type rea!tion $ariant8 as e$ery patienthas his o%n and his indi$idual type of rea!tion %ith %hi!h he responds to ea!h sti#ulationtherapy. These are #ostly gradual differen!es, p. 1, #y Tb! boo*8

It is no%here !learly e<plained %hy nor#al allergies suppressed %hen tuber!ulosis is a!ti$e

and %hy they reappear %hen the tuber!ulosis pro!ess i#pro$es. Aor#al allergi! or e$]anaphyla!ti! rea!tions appear %hen the poisons ha$e obtained *ind of pea* and the body is ableto neutralize, &digest and eli#inate the#, 2neu#onia healed in for#er ti#es after the body had

produ!ed a deto<i!ation !risis %ith abundant perspira-tion, diarrhea and so#eti#es $o#iting.Then healing set in. The $isible syndro#es are the a!!o#panying bodily signs of that *ind ofdeto<i!ation or !leansing rea!tionR%ith lo!al and general sy#pto#s %hi!h !an also be regardedas the start of a healing pro!ess. The therapy has to i#itate the deto<i!ation. fter thateli#ination, patients %ith asth#a, #igraine or gout feel greatly relie$ed,

s for nutrition, it is ne!essary to *eep a%ay all substan!e fro# the si!* body %hi!h !an produ!e allergi! and other biologi!ally stronger rea!tions su!h as !aused by fats, ani#al proteins,$ita#ins e<!ept $ita#in C and nia!in8 and hor#ones, be!ause

1(9 3i!ht%itz, @lin, #hemte, 19, p. 14.

they !ountera!t the nor#al allergi! healing rea!tion %hi!h is so ne!essary in the beginning to *illthe tu#or tissue. This per!eption sho%s four !onse+uen!es !learly

18 The strongest deto<i!ation not only #e!hani!ally by ene#as8 is in !an!er the conditio

sine 2ua non for the start of the healing. poisoned body is anergi! and !annot rea!t to thefa$orable side. The detoxified body can.

(8 The #aintenan!e of the deto<i!ation is absolutely ne!essary and the greatest therapeuti!alhelp for the li$er.

8 The li$er, the #ain transfor#ation and eli#ination organ, #ust be able to indu!e the

pro!edure, to #aintain it, e$en if it has to undergo so#e proteolyti! pro!esses, %hi!h parti!ularly hit the li$er !ells, a!!ording to E. ?. 2i!*.1

;8 The healing is li#ited or e$en i#possible in !ases %here and %hen the li$er is no longerable to render and #aintain this $ital ser$i!e of !onstant deto<i!ation and te#porary allergi!rea!tion to the body.

L. Lensen stated, It #ust be e#phasized that the %hole sub5e!t of allergy is $ast and !o#ple<and that it still has #any proble#s %hi!h are as yet unsol$ed.11 The !onfusion be!o#es e$engreater %hen %e see the #a5ority of the !an!er authors push the allergy proble# aside asunessential or do not #ention it at all.

. ?. Co!a reported that all of (97 persons %ith #alignant gro%ths of the breast presented

sy#pto#s of idioblapti! allergyO t%o persons a!!identally in!luded in the group %ere found to befree fro# idioblapti! !onstitution and both of these had had non-#alignant gro%ths of the breast.1(



In his !hapter on >iagnosis of llergy, Lensen !on!luded, The ans%er depends upon theirdefinition of allergy.1 E$ery author #a*es his o%n definition.

The allergy proble# is tou!hed upon here only to #a*e the healing of !an!er understandable.To eli#inate !onfusion, I suggest the follo%ing

n allergi! rea!tion #ay be thought to be a diminished 1C- r!h. f. e<per. 2ath, 7, :9, 191;.

1:1 L. Lensen, Modern #oncepts in Medicine, C. . =osby, 19), p, 47.1( rthur ?. Coea, 7amilial "onreaginic 7ood $llergy, p. 1:).1CC Lensen, Modern #oncepts in Medicine, p. 4.

enzy#ati! rea!tion 3i!ht%itz8, an allergi! infla##ation to be an in!reased enzy#ati! rea!tion$on erg#ann8. oth are enzy#ati! by nature and both are !aused by the fun!tion of the sa#eapparatus, !apillary endothelRor reti!uloendothelial syste#-s#all arteries, $is!eral ner$oussyste# and enzy#es a!ti$ated and supported by the li$er8. Therefore, the na#e allergy is

5ustified in des!ribing these different rea!tion !o#ple<es. In reality, the degree only is different as%ell as the pla!e of response. iologi!ally, it !an be regarded as an unspe!ifi!, healing-indu!inginfla##ation. It is a stru!tural response to an i##une pro!ess beyond the li#its of physiologi!al

fun!tion. "hether or not the body !an a!!o#plish the healing pro!ess re#ains still +uestionable.?urther de$elop#ent during the treat#ent %ill sho% if the body !an be restored suffi!iently toa!!o#plish it.

The tas* of the therapy is to pre$ent all i#peding infe!tious or poisonous rea!tions in!ludingthose !aused by drug allergies and allergies to food %hen not digested to the end produ!ts8.These %ill hinder the allergi! healing infla##ation.

C-APT1R =I=

Introduction to the $iet

>iet, in the sense of 'ippo!rates, is a !o#plete regi#e regulated by the fa#ily physi!iana!!ording to #edi!al indi!ations. Autrition should be regarded as a re#edy, pres!ribed as to *indand +uantity or ite#s to be forbidden. Autritional pres!riptions are a part of the total therapy

only and #ust be !o#pleted by other pres!riptions. The *no%ledge of su!h additional therapy isindispensable for the pra!ti!e. fe% dire!ti$es as to the effe!ti$eness on the $arious organs ofresponse should be des!ribed in ad$an!e.

"hen I started the first treat#ent, %ee*s and #onths produ!ed an in!reased sensiti$ity to%ard$arious natural sti#uli !aused by nutrition and #edi!ation. This in!reased sensiti$ity had so#e

benefi!ial effe!ts, but also so#e da#aging ones. /n the one hand, it helped to atta!* the tu#orand #etastases $ery +ui!*ly, but on the other, it #ade it diffi!ult to feed the patients, as $ariousallergies de$eloped, for instan!e, against li$er in5e!tions, li$er 5ui!eJ, orange 5ui!e, #inutea#ounts of le#on, and different fruits and #edi!ations. #ong the #edi!ations the #oststri*ing %ere opiates, !odeine, no$o!aine all types8, peni!illin and other antibioti!s. It be!a#ene!essary to find #eans of e<!luding all allergi! rea!tions as far as possible. "e su!!eeded ine<!luding the nutritional allergies by adding large doses of potassiu# and si#ultaneouslyapplying a stri!tly saltless diet, in!reasing the doses of lugol solution and thyroid and in!reasingdeto<i!ation by #eans of additional !offee ene#as and #ore fre+uent !astor oil treat#ents.2atients re#ained sensiti$e to N-rays, so that e$en fluoros!opi! e<a#inations %ere da#aging

and had to be o#itted as far as possible. They also re#ained sensiti$e to prolonged e<posure tosunshine. 'ypersensiti$ity to

J ee ppendi< III. page ;(1



no$o!aine also persisted, so that dentists %ere ad$ised not to use #ore than a third of the nor#aldose of ( !! .4-.7 !!8. nesthesia %ith this redu!ed dosage pro$ed e$en #ore effe!ti$e thanthat for#erly a!hie$ed %ith the nor#al a#ount 2atients also retained a hypersensiti$ity to

physi!al and #ental e<ertion, so that a #a<i#u# of rest %as ne!essary during the first #onths.E$en after four or si< %ee*s of treat#ent the #ore ad$an!ed patients %ere generally unable to

do #ar*eting and prepare the diet and 5ui!es by the#sel$es. If there is a !ondition of perspiration,%ea*ness and depression, the entire body should be rubbed t%o or three ti#es a day %ith a soft

brush %rapped in a %ash!loth and soa*ed in the follo%ing solution one-half glass of %ater to%hi!h is added t%o tablespoons of rubbing al!ohol and t%o tablespoons of %ine $inegar.

The general fun!tion of the dietary regi#e, as de$eloped by #e originally for the treat#ent oftuber!ulosis, %as regarded in #any different %ays by $arious authors %ho had spent years of%or* %ith it. /ne !alled it anti-phlogisti!, another, dehydrating, a third, in!reasing the fa$orableinfla##atory pro!ess, a fourth, a!id-for#ing, a fifth, al*alizing, and yet another, in!reasing thehealing pro!esses in the syste# by unspe!ifi! sti#ulation therapy. The truth of the #atter is that#ost of the abo$e opinions are !orre!t-they are partial effe!ts %hi!h, ta*en all together, #ay bee<pressed as aid in the sense that it is a!ti$ating the healing pro!ess in the %hole syste#.

In biology the study of the fun!tions of one substan!e in an organ is $ery diffi!ult anddisappointing.

zent-Gydrgyi says the #ore %e study and *no% the single rea!tions of the #us!les, the less%e understand its fun!tion-and the fun!tion is a part of the %hole body. In e<peri#ents onfoodstuffs, s!ientists also e<a#ine single ite#s in different si!*nesses. The results are often $ery!ontradi!tory.

>r. le<ander runs!h%ig of Ae% For* =e#orial 'ospital %as puzzled about the i##unity pheno#enon in !an!er, as #ost surgeons are. The e<isten!e of so#e bodily defense against !an!er!an hardly be denied. ut at best this defense is relati$ely feeble. "hat is #ore proper thanto strengthen the defense, %hi!h, in a higher degree, #eans the healing po%er

It is %ell *no%n that #y approa!h of studying the whole #etabolis# in its rea!tion is !ontraryto the pre$ailing $ie%point of the #edi!al profession, %hi!h adheres generally to the thought thatso#ething spe!ifi!, su!h as one #edi!ation, or a spe!ifi! seru#, or a !o#bination of differentsera, %ill ha$e to sol$e the !an!er proble#. It has be!o#e #ore e$ident of late that theappli!ation of surgery and N-rays is en!ountering #ore s*epti!is# by so#e surgeons and the

publi!.@ntil $ery re!ently, it appeared that %hate$er did not fit or agree %ith the pre$ailing pra!ti!e or

do!trine %as not s!ientifi! and %as pushed aside.1; Aone of the so-!alled food-fanati!s probably assu#es that one or the other ite#, used on!e, for a %ee*, or for a year, %ill prepare theunderlying !onditions for !an!er. This boo* e<plains that chronic into<i!ation and degenerationof the li$er-pan!reas apparatus and the %hole #etabolis# #ay !ause the underlying !onditions for

!an!er. ll other superfi!ial presentations are #is!on!eptions and #islead the reader. Theintrodu!tion to the abo$e-#entioned arti!le reads as follo%sugar, %hite flour, preser$es, spi!es, !heese, !anned goods, !oo*ed foods and to#atoes all

!ause !an!er, %e hear. Grapes, on the other hand, !an %ard off !an!er and e$en !ure it. Theseare so#e of the #is!on!eptions about !an!er %hi!h $arious food-fanati!s and !ra!*pots ha$e heldthroughout the ages.

Aone of the#, of !ourse, is true. !ien!e has not found that any dietary ite# !an lessen one&s!han!es of getting !an!er or re!o$ering fro# !an!er. lu#inu# !oo*ing utensils %ere on!ethought by so#e to !ause !an!er. =any people still belie$e that !he#i!al fertilizers, used insteadof the old-fashioned organi! *ind, #a*e people #ore sus!eptible to !an!er. nother #yth %hi!hhas gro%n only in !o#parati$ely re!ent years is that %ater fluoridation !auses !an!er.1)

"hat other s!ientists and their follo%ers assu#e is so#ething entirely different. Their opinionrepeated in short is, that #any different da#aging food ite#s, ta*en together, or in !o#bination%ith other da#aging fa!tors, su!h as artifi!ial fertilizer, alu#inu# *it!hen utensils, and dead food



su!h as frozen food or food

1; The introdu!tion to the arti!le %nvironmental #ancer in #ancer "ews 19)4, ol. N, Ao. , p. 8 !an be regarded as the #irror of thought of the #a5ority of leading authors in the #edi!al profession. In thatarti!le all see#s to be based on s!ien!e and s!ien!e e<peri#ents and s!ientifi! *no%ledge. Inreality, ho%e$er, this all is tal*ing around the !ore of the issue and e$ading the real proble#.

*() <bid.

!hanged by !he#i!al additions for preser$ation, and in addition other defi!ien!ies in food,!aused by refining pro!esses or poisons !aused by !anning, et!., all ta*en together, !an seriouslyinfluen!e and !ontinue to influen!e our body and its $ital organs. Aobody !an re!onstru!t su!h!onditions in ani#al e<peri#ents, but #any obser$ations in the history of peoples de#onstratetheir do%nfall by influen!es of !i$ilization in a broad sense. u!h a!!u#ulations not one oranother ite#8 of poisons prepare the !onditions for !an!er diseases. In #any !ases, e$en thelifespan of a physi!ian&s pra!ti!e is not suffi!ient to obser$e in #any people the a!!u#ulation ofall da#ages, as it #ay ta*e si<ty to se$enty years or longer to obser$e the outbrea* of the diseasein healthy people %ith a strong body, a resistant li$er and good reabsorption po%er.

It goes %ithout saying that $egetarians also get !an!er. o#e of the# !on!ludeRho% !an su!ha treat#ent help against !an!er %hen e$en $egetarians #ay be!o#e affli!ted

18 they do not *no% %hat !onditions are ne!essary to #aintain the nor#al #etabolis#R (8 that our #odern agri!ulture de!reased potassiu# and iodine in our nutrition, pre!isely the

#inerals essential for pre$ention of !an!erR 8 that so#e people %ith %ea* organs are not suffi!iently prote!ted by diet aloneE

;8 the therapy !o#prises #u!h more than a $egetarian diet and has been su!!essful in so#e$egetarians also.

s far as I *no%, e<peri#ents %ith the %hole #etabolis# in that respe!t are not being !arriedout any%here in the %orld. ll the e<peri#ents perfor#ed in that dire!tion in the past t%enty orthirty years sho% #ostly the abo$e-#entioned influen!e of single ite#s on the %hole

#etabolis#. The results of these e<peri#ents are partly !ontradi!tory and partly !onfli!t %ithother ideas. This is understandable, as ani#als and hu#ans $ary !onsiderably in their #etaboli!e+uilibriu#.

The a#ount of da#age done by !he#i!al fertilizers, spraying, and inse!ti!ides %hi!h lead to a!hroni! poisoning of the soil !an be esti#ated %hen %e realize ho% #any poisons go into thefruit and $egetables %e eat, into the !attle, the eggs and butter %e !onsu#e and the #il* %hi!h%e and our !hildren drin*. "e also ha$e to realize the enor#ous a#ount of food one patientneeds in a single year. 'ere is a re!ord of the a$erage +uantity of inta*e of so#e patients in the!ourse of one yearO a $ery great part of %hi!h is !on$erted into 5ui!es.

1: pounds of !arrots

1 pounds of apples)-;) pounds of !alf&s li$er 5ui!e8J1;) heads of red !abbage; heads of lettu!e1() pounds of green peppers, et!., et!.

I a# #ore than e$er !on$in!ed that bio!he#istry and #etaboli! s!ien!e %ill be $i!torious inhealing degenerati$e diseases, in!luding !an!er if the whole body or the whole metabolism %ill

be atta!*ed and not the sy#pto#s.

J ee ppendi< III, page ;(1

C-APT1R ==



>r. is*ind&s and >. ?. =. 2ottenger, Lr.&s obser$ations sho%ed that in the years fro# 19;) to19), blood !holesterol in his patients %as in!reased, a!tually !aused by ne%er inse!ti!ides.

In e<peri#ents of the ?ederal ?ood and >rug d#inistration %ith inse!ti!ides fi$e days afterfeeding sho%ed the inse!ti!ides in the gizzard, the li$er and the *idney, the tissues of the heartand brain and s!iati! ner$e fibre.

"ith larger doses, ?.>.. s!ientists ha$e also sho%n that it is possible to store #any ti#es the

a#ount in the body-fat that %ould be a!utely fatal intra$enously in a single dose. in!e >>T#obilizes fro# the body fat into the blood strea#, the intra$enous dose is the logi!al !o#parati$eone. Cu#ulati$e into<i!ation fro# e<tre#ely s#all a#ounts in food !an thus be as dangerous asdire!t e<posure to #u!h larger a#ounts.

The soil is the #eeting pla!e of the li$ing #atter at the surfa!e and of the #ineral #atter beneath the surfa!e, and of the at#osphere abo$e and the solid ro!* underneath. Essentially allli$ing #atter depends upon it, dire!tly or indire!tlyRis, in fa!t, a part of those $ery pro!essesthat produ!e the soil upon %hi!h life depends. 2lants and soils ha$e gro%n up together, ea!h

partly a !ause of the other. =an has so#e%hat the sa#e relationship to the soils. 'e finds so#eare better suited to his needs than others. 'e #ay !hange the# either for better or for %orse.1:

oil s!ien!e has a !ontribution to #a*e to%ard the future, but !ertainly not by itself. in!e

s!ien!e itself has be!o#e so spe!ialized, it is diffi!ult to see s!ien!e as a %hole and its rela-tionship to politi!s, art, business, and agri!ulture. =ore and #ore, #ode# edu!ation see#s to#a*e people spe!ialistsR#e#bers of a group or !li+ueRand leads the# a%ay fro# the #asses,fro# real de#o!ra!y. The *ind of s!ien!e that is super-spe!ialized !annot lead people to betterrelationships %ith ea!h other and the land, nor !an so-!alled pure s!ien!e, %hi!h is too !old ortoo snobbish to fa!e the real proble#s. o#e see a danger that far#ers as %ell as other people#ay turn their proble#s o$er to so#e spe!ial group, so#e spe!ial bureau!ra!y, rather than tothin* out the proble#s for the#sel$es and #a*e their de!isions by the de#o!rati! #ethod.

1: Charles E. Pellog. The =!=illan Co#pany, 19)4.

There e<ist abundant supplies of nearly all natural resour!es in the @nited tates and espe!iallyof soil. Enough in5ury to the soil has ta*en pla!e to indi!ate a pressing need for ad5ust#ents ofagri!ultural people to the soil upon %hi!h they li$e. in!e there are #any soils theserelationships are too !o#pli!ated to be resol$ed by a fe% si#ple slogans or progra#s.

The #odern te!hni+ue of !anned food goes ba!* to the appli!ation of heat by the atte#pts ofpperts %ho tried to gain the a%ard, established by Aapoleon in 179), for the best plan for food!onser$ation for his ar#y. In 1:;, he published his %or*. In 1:1, 2eter >urand re!ei$ed thefirst English patent for the #etal !an. In 1:;1 the first fa!tory for !anned food %as founded in

Aor%ay. 3ater in 1:;) the first fa!tory in >essau, Ger#any, %as established. In 1:7, 6obertPo!h introdu!ed the auto!la$e. In 1:)9, fa!tories for !anned food %ere set up in the @nitedtates. In 1:79, the first !ans for sardines %ere #ade in ta$anger, Aor%ay. In 197, the

produ!tion of !anned $egetables in the @nited tates a#ounted to 1:9,919, !ratesO there also%ere 4,7;;, !rates of fruits and 1(,, !rates of fish. The te!hni+ue of frozen food %asintrodu!ed by C. $on 3inde 1918. The te!hni+ue of !onser$ation is an!ient. It begins %ith theuse of salt for #eat and fish and $egetables, and the use of sugar for fruit. It be!a#e #orede$eloped in our #odern bio!he#istry.19

The !anned food industry has gro%n into an i#portant fa!tor in our #odern !i$ilization. Thus,the nutrition and feeding of fa#ilies has been put on a #ass produ!tion basis. The !ans stay inthe foreground and the #ista*es in that respe!t, no #atter ho% insignifi!ant they #ay appear,

be!a#e an e$er-in!reasing !ala#ity in our present day so!iety.". C. Pinney, of ista, California, re!ently produ!ed on his organi! far# apri!ots on

!o#posted, #ineralized soil that !ontain the follo%ing analysis=oisture :4.1)Zsh . .7Z



2rotein 1.;1ZP (/ ;1) pp#

Aa 7;: pp#Ca/ (91 pp#

19 "erner Pollath, ibid., pp. 7-71.

=g/ 49.( pp#2(/) 1;. pp# 1).( pp#?e (.: pp#=n 4.9 pp# 0.(: pp#Cu 0.49 pp#

The in!reased protein !ontent also has #any disad$antages. 1J E!ono#i! pressure, in ter#s oflo%er a!tual !ash returns for the far#er&s !rops, has brought a ne% ele#ent into the planning andthin*ing of so#e of our top agrono#ists. The gro%er&s pay for his year&s %or* is being

!onsiderably redu!ed through the toll ta*en by pests and disease. o the e#phasis is beingshifted, at least in so#e +uarters, to the de$elop#ent of resistant plants and to biological

controls instead of poisons.long %ith this trend there is 5ust beginning to be a realization of the fa!t that in!reasing

nu#bers of !onsu#ers are %illing to pay top pri!es for really high +uality foods. In this regard,the #ost ad$an!ed resear!h sho%s that high protein !ontent by itself is not ne!essarily theans%er. "or* %ith the a#ino a!ids has sho%n, a#ong other things, that high protein broughtabout by e<!essi$e nitrogen fertilizing !an a!tually lessen rather than in!rease the nutritional$alue of grains and $egetables. t the sa#e ti#e, s!ientifi!ally #anaged organic fertili:ing !angi$e better results, in ter#s of food $alues, e$en %ith a relati$ely lower protein !ontent.

In the "ew =ork ;orld9Telegram 'un, =ay :, 19)7, an arti!le reported that 6o!*land

County&s stra%berry !rop is ruined, the rest of the !ounty&s ^(,, fruit !rop is threatenedand $irtually e$ery bee in the !ounty has been *illed by the >epart#ent of gri!ulture&s #assi$eaerial spray of >>T, the state agri!ulture agent of the !ounty !harged today.

In #y opinion, it %as not the one spraying that !aused su!h disastrous da#age, as the pre$ious1( years of in!reased spraying %ith in!reased poisons produ!ed an a!!u#ulated to<i! and

pathologi!al !ondition in soil, ani#als and hu#an beings. I !alled it our E<ternal =etabolis#see page 1), line 18.

1; E. E. 2feiffer, =.>., &alan!ed Autrition of oils and 2lants, "atural 7ood 7arming, =ay 19)7, p. 4.

The arti!le !on!luded as follo%s >>T is, and is re!ognized and ad#itted by the defendants to be, a delayed-a!tion, !u#ulati$e poison su!h as %ill ine$itably !ause irreparable in5ury and deathto all li$ing things, in!luding hu#an beings, ani#als, birds, inse!ts and the predators and parasitesof har#ful inse!ts, if ingested, inhaled or brought into !onta!t there%ith in suffi!ient +uantities oro$er a suffi!ient period.

o#e hu#an beings, in!luding so#e of the plaintiffs, ha$e already absorbed . . . and no%irre#ediably retain in their bodies an a!!u#ulated a#ount of >>T %hi!h is to<i! and

pathologi!al, so that the threatened spraying upon their persons %ill endanger their health andli$es, and the threatened spraying on their gardens and other !ulti$ated lands %ill #a*e it unsafefor the#, this year, or e$en thereafter, to eat the produ!e therefro#.

A@T6ITI/A S>ETE6I/6TI/A8

The preparation of the 5ui!es is des!ribed in the pres!ription boo*let. There, the physi!ian %ill



find an outline of the diet as it is used at the present ti#e and also a des!ription of the preparationof $egetables. The pres!ription boo*let also !ontains an outline of the #edi!ation %ithoutindi!ating the e<a!t doses. Instead of that, one !an!er !ase is presented in full detail, fro#

beginning to end. I belie$e that the physi!ian %ill thus ha$e

T!BL( I

Potassium sodium

Applet !-/ !/#otatoes **0 !" In !00 'rams fresh su8stance$urnips 33- /" Ash content of the edi8le por tionCa88a'e -*3 -0 of some common foods(ima 8eans,dried !.*3 -*/ 9modified from (us:;

&atmeal 30 !

a #u!h !learer idea of ho% the #edi!al treat#ent !an be applied in the best #anner. The detailsof the agri!ulture of foods and $egetables !annot be gi$en in extenso in this $olu#e. pa!e %illonly per#it a fe% brief !hapters to deal %ith the proble#s of artifi!ial fertilizers, organi!

gardening #ethods, the poisons of spraying and all other fa!tors da#aging to foods and$egetables in their preparation and distribution. K Chapter .8

?or the !hoi!e of fruits and $egetables, it %as #ost i#portant to *no% the potassiu# !ontent as%ell as the sodiu# !ontent.1;1 The table sho%s that the potato has the lo%est sodiu# !ontent, of19 #illigra#s in 1 gra#s of fresh substan!e, %hile the potassiu# !ontent is ;; #illigra#s, or( ti#es as #u!h. The !ontent of the apple is fifteen to 1(), or about eight and one-half ti#es as#u!h.

The a!!ura!y of this table is +uite un!ertain, as the $egetables, fruit and #il* sho% +uitedifferent figures at different ti#es. The #ore our agri!ulture turns a%ay fro# natural #ethods, the

#ore the !ontents of fruits and $egetables are !hanged the sodiu# !ontent rises, the potassiu#!ontent di#inishes.In the near future, hospitals and !an!er !lini!s and !lini!s for !hroni! degenerati$e diseases

%ill be #ore or less for!ed to use fruits and $egetables gro%n by organi! gardening #ethods, or%e physi!ians %ill see that our results and therapeuti! su!!esses of the treat#ents %ill be fe%erand fe%er.

The poisoned soil %ill not only help to in!rease degenerati$e diseases, but it %ill also redu!e thehealing po%er of the body %hen brought under spe!ial !onditions %here it fun!tioned fa$orably

pre$iously.1;1 ee the Physiological 4asis of Medical Practice, )th edition, by Chas. '. est and Aor#an ur*e

Taylor, p. 77 The "illia#s and "il*ins Co., 19)8.

C-APT1R ==I

The Saltless $iet

T'E 6/3E of salt in hu#an nutrition has been a disputed sub5e!t for a long ti#e. o#e authorsregard salt #erely as a !ondi#ent or sti#ulant %hi!h is har#less in s#all +uantities, possiblyhar#ful in larger +uantities, but definitely dispensable in nor#al nutrition, to the e<tent that it is

not a natural !ontent of food. /thers belie$e that salt is indispensable in hu#an nutrition and thatthe sodiu# !hloride found in foods is not enough to #eet the re+uire#ents of the nor#al hu#an being.



The e<ponents of both $ie%s ha$e gi$en reasons in support of their respe!ti$e $ie%points."olff-Eisner asserts that salt is !o#parable to a $ita#in, and that its !o#plete e<!lusion !ould

not be tolerated any longer than the e<!lusion of food itself. It #ight be argued here that!o#plete e<!lusion is i#possible any%ay, inas#u!h as $arying +uantities of AaCl are found infood naturally.8

"olff-Eisner adds, ho%e$er, . . . that !oo*ing salt is the only salt %hi!h does not o!!ur in

suffi!ient +uantities in nor#al nutrition and that it, therefore, #ust be added artifi!ially.&& Thereare different $ie%s as to the +uantity of salt %hi!h, a!!ording to this theory, #ust be added to!o$er #an&s salt re+uire#ents.

The a$erage European !onsu#es ten to fifteen gra#s of salt per day and in the @nited tatesthe a$erage !onsu#ption is ten to t%el$e gra#s per day, %hereas the $alues are +uite different insia and fri!a. ll physiologists agree that these $alues far e<!eed the salt re+uire#ents. Inother %ords, they agree that people !onsu#e salt #ostly be!ause it #a*es food #ore tasty, not

be!ause the body re+uires it.unge !ondu!ted se$eral e<peri#ents in 191 on the need

for salt. 'e found a s#all de#and for salt in ani#als %hi!h eat a lot of #eat, %hereas hedis!o$ered the de#and #u!h greater in those li$ing on $egetation. 'e belie$ed that the sa#erelationship %as to be found a#ong hu#an beings. 'e found that the population of !ities, in%hi!h larger +uantities of #eat %ere eaten, !onsu#ed one-third of the +uantity of salt used bythe #ainly $egetarian rural population. i#ilarly, he found little de#and for salt a#ong the#eat-eating no#ads, /n the other hand, the salt de#and a#ong agri!ultural negroes %as sogreat that, in so#e tribes, salt a!tually had barter $alue.

?ro# his o%n e<peri#ents, unge gathered that the body eli#inates large +uantities of salt if it!onsu#es #u!h potassiu#, su!h as found in large +uantities in $egetarian nutrition. 'is!lassi!al e<peri#ent in 191, ho%e$er, is not indisputable in theory, although its !on!lusions are!orre!t.8

bderhalden shared unge&s $ie%s as to the reasons for the in!reased de#and for salt a#ong

$egetarian tribes The higher potassiu# !ontent of nutrition leads to in!reased eli#ination ofsodiu# and, therefore, !auses an in!reased de#and for salt.unge !onsidered the addition of four to fi$e gra#s of salt daily ne!essary for the #aintenan!e

of the salt balan!e per oit8O 'er#annsdorfer disputed this in his do!torate dissertation,stating that %hile #an !onsu#es up to 1) gra#s of salt per day, he !ould undoubtedly #anageon one or t%o gra#s of salt. In fasting e<peri#ents on hi#self, to test the eli#ination of salt,'er#annsdorfer generally too* t%o gra#s of salt.

These $ie%s are !onsidered one-sided in so#e respe!ts despite their ha$ing !o##on usage.=y e<peri#ents on thousands of patients, as %ell as on #yself, re$eal that the de#and for salt isso#ething to %hi!h our ner$es of taste ha$e be!o#e a!!usto#ed sin!e youth. Lust as one #ightsay that all people ha$e a need for al!oholi! be$erages and that e$en ani#alsRespe!ially the

hu#an-li*e apesR!an be!o#e !hroni! al!oholi!s, and, !on!luding fro# this fa!t that al!ohol isa ne!essary !o#ponent of hu#an nutrition, it %ould be 5ust as in!orre!t to base a !lai# of the indispensability of salt on its uni$ersally pra!ti!ed use.

There are !ertain tribes %hi!h do not use salt, 'o#er has #entioned the#, and allust tal*ed ofthe Au#idians %ho did not use salt. ut apart fro# that, e$en if all the people in the %orld hadeaten salt sin!e ti#e i##e#orial, this still %ould not pro$e that it %as to their ad$antage. fterall, there had al%ays been !hroni! diseases %hose etiology %e !annot as!ertain e$en todayO thus,%e !annot 5udge to %hat e<tent they #ay ha$e been !aused by an unreasonable %ay of life.

Lust for the sa*e of !uriosity, %e #ight point to the fa!t that, e$en today, there are tribes %holi$e %ithout salt. 2rofessor rgo! reported that tuber!ulosis %as unusually pre$alent a#ong thesettled Pirghizians, %hereas it o!!urred only rarely a#ong the no#adi! ones. 1;( The no#ads use

no salt, %hereas the Pirghizian peasants do use salt, %hi!h is freely a$ailable in the teppes, asan addition to nutrition, in the #anner of the 6ussian peasants. Aote the role of @umysE strongal!oholR%ill not be dealt %ith here.8 The Pirghizians reported to rgo! that they had noti!ed a



deterioration of their senses of sight and s#ell sin!e parta*ing of bread and salt. Ao#ads %house salt lose the ability to s!ent %ol$es. rgo! also reported that fishing and hunting tribes ofiberia sho% a #ar*ed disli*e of salt. /n his e<peditions to the Aorth 2ole, Aansen used theEs*i#os& disli*e of salt to get rid of unin$ited guests by offering the# strongly salted food.tanley and 3i$ingstone, too, reported on finding tribes to %ho# salt %as un*no%n and %hosho%ed !ertain to<i! sy#pto#s after ta*ing it for the first ti#e. lso see lbert !h%eitzer&s

report.8"e obser$ed healthy nurses after se$eral #onths of unsalted nutrition and found that their first

rea!tion to nor#al ho#e-!oo*ing %as diarrhea and nausea. This sho%s %hat far-rea!hing effe!tsthe habitual !onsu#ption of salt #ay ha$e on the organis#. fter going si< #onths %ithout salt,a nurse %ho had belie$ed that she !ould not do %ithout it rea!ted to this spi!e as a young boyrea!ts to his first !igarette.

The e$aluation of al!ohol, toba!!o and salt as parts of hu#an nutrition is !losely !onne!ted%ith national and e$en religious and politi!al #oti$es %hi!h are not al%ays related to #edi!al!onsiderations. It %ould, therefore, be %ise to o#it the ethnographi! aspe!t fro# a dis!ussion ofthe #eaning of salt in hu#an nutrition. "e should also a$oid the #ista*e of +uoting e<a#plesfro# the ani#al %orld to pro$e that the inta*e of salt is natural

1;( Quoted in Dtsch. $er:te:eitung. 1741(9.

or ne!essary. "e ha$e refused to use the argu#ent of natural nutritionO this ter# #ust bere5e!ted %hen usedRapparentlyRto the disad$antage of the diet. "hether a for# of nutrition isnatural or not has nothing to do %ith the +uestion of %hether or not it is of therapeuti! $alue indiseases. This is the only de!isi$e +uestion in pra!ti!e. Ae$ertheless, for the sa*e of !o#pleteness, a fe% brief re#ar*s regarding the desire for salt in

ani#als are in order.In areas of great e<panse, su!h as in Central India and in the >e**an, there is an enor#ous

%ealth of ga#e and no a$ailability of salt. 2resu#ably, the sa#e situation e<ists else%here. It is

of spe!ial i#portan!e to note that apes in parti!ular sho% no need for saltO #i<ed hu#annutrition is offered to the# only in !apti$ity, %hen they a!!ept it as readily as they learn to drin*al!ohol, s#o*e toba!!o and eat roast #eat.

!!ording to >r. Gusta$ 6iedlin, thorough e<peri#ents in the use of salt %ere !ondu!ted by'ahne#ann, the founder of ho#eopathy, and his students. In these e<peri#ents, 'ahne#annand his students !onsu#ed !onsiderably greater +uantities of salt for %ee*s and #onths thanthey %ere nor#ally a!!usto#ed to !onsu#e in food. The har#ful effe!ts are des!ribed in the

boo* pp. 9-1)8.1;(

rgu#ents against a saltless diet saltless #eans %ithout addition of salt to food8 %ereenu#erated by "olff-Eisner; appro<i#ately as follo%s

In a nutrition ri!h in $egetables, the body re+uires the addition of salt, as this does not o!!ur in

suffi!ient +uantities in the food as the only salt. s the potassiu# !arbonate of $egetables!o#bines in the organis# %ith !hloride and sodiu# to for# sodiu# !hloride and sodiu#!arbonate, it !auses the eli#ination of !hloride and sodiu#. This #eans that sodiu# as %ell as!hloride #ust be gi$en to the body to #a*e up this lossRhen!e the addition of salt

In this %or*, "olff-Eisner +uotes the %ell-*no%n e<peri#ents of unge, %ho asserted thatregular parta*ing of potatoes, %hi!h !ontain 1-;( ti#es #ore potassiu# than sodiu#, is

possible only if AaCl is added to this food.

&Gusta$ 6iedlin, Das @ochsal: 8'alt3, Ed. 2aul 3oreoz, ?reiburg, 19(;.1;; It should be noted here that not only salt, but also fruity a!ids parti!ipate

in su!h !hanges of the #etabolis#.T'E 3T3E >IET

In the sa#e %or*, strangely enough, it is #entioned that a8 apples !ontain e$en 1 ti#es #ore potassiu# than sodiu#, yet one #ay !onsu#e large +uantities of applesRone #ay e$en ha$ee<!lusi$e apple daysR%ithout the addition of AaCl. b8 !!ording to general opinion, the



hydro!hlori! a!id of the sto#a!h is dependent on the body&s salt inta*e. Therefore, if the inta*eof salt is #issing, the for#ation of hydro!hlori! a!id #ust de!rease, %hi!h %ould affe!t appetite,digestion, et!. for la!* of salt inhibits produ!tion of hydro!hlori! a!id. !8 ?inally, "olff-Eisnerre#ar*s that the s%eat of tuber!ular patients !ontains up to one per !ent salt, so that perspirationdepri$es the body of salt.1;) d8 ?urther#ore, it is said that the *idneys regulate the body&s ioni!stateO in fe$er and in the #a5ority of infe!tious diseases, the salt !ontent of the urine is

di#inished, e$en if the patients are gi$en salt. Conse+uently, it is argued, there is no need toregulate the inta*e of salt, if the *idneys are healthy, as the *idneys regulate the eli#ination ofsalt any%ay. in!e, a!!ording to 6oth-Poe$esti, e$en diseased *idneys are !apable of eli#inatingfi$e gra#s of salt in a liter of urine, the inta*e of fi$e gra#s of salt is unob5e!tionable for su!h*idneys.U

Inas#u!h as so#e of these argu#ents are also $oi!ed by our patients, %ho see parti!ularnutriti$e $alue in salt and appre!iate the sti#ulati$e effe!t of salt upon appetite and thirst,

physi!ians are so#eti#es for!ed to ta*e the# into !onsideration.s far as "olff-Eisner&s first argu#ent is !on!erned, it #ust only be said that that %hi!h

appears ob5e!tionable to hi# is parti!ularly desired by #e, i.e., the in!reased eli#ination of AaCl.?or if, "olff-Eisner&s presentation, %hi!h is based on unge&s $ie%, is !orre!t, i.e., if the

eli#ination of AaCl fro# the body&s salt resour!es is furthered by $egetarian nutrition, it is pre!isely that %hi!h #y diet %ants to a!hie$e. The #ore salt is eli#inated by it, the #oreeffe!ti$e the diet is in so#e respe!ts. It appears to us that it %ould be e+ually ine<pedient torepla!e the de!reased sodiu# and !hloride, %hi!h %e desire, by the feeding of salt, as it %ould beine<pedient to #a*e up in!reased eli#ination of sugar in the urine of diabeti!s by in!reasingsugar inta*e.

Ao hu#an dietaries, ho%soe$er pres!ribed, e$en %ithout added salt, are so lo% in sodiu#that they !annot support life.1;:

1;) Med. ;elt, 19(9, p. 1:(1.1;4 ee lfred T. hohl, Mineral Metabolism, p. 1(1.

The argu#ent for the ne!essity of the addition of salt to potatoes %as #entioned abo$e, as%ell as the fa!t that apples-!ontaining 1 ti#es #ore potassiu# than sodiu#Rare not salted,e<!ept by spe!ial gour#ets. This sho%s the i#portan!e of the role of habit and taste. 2easants%ould laugh at people %ho add salt to apples, yet they add salt to potatoes the#sel$es.8

It is *no%n that there is a !onne!tion bet%een the hydro!hlori! a!id of the sto#a!h and theinta*e of salt. 'o%e$er, the dependen!e of this hydro!hlori! a!id upon salt inta*e has not been

pro$en, and is !ontrary to #y e<perien!e.1;7 !!ording to 6ose#ann, the sto#a!h 5ui!es ofnor#al hu#ans !ontain ;-) #g. of hydro!hlori! a!id. Its p' lies bet%een .97 and .:. If%e !onsider the regulation for the produ!tion of sto#a!h 5ui!e, it sho%s ho% the entire organis#,espe!ially the li$er, parti!ipates in its for#ation, 5ust as it parti!ipates in all other bodily o!!ur-

ren!es, irrespe!ti$e of the organ in %hi!h the parti!ular pro!ess ta*es pla!e.

-5/ /-IT1 MA2%S $I1T A??1CTS 2ATI.1S 5? A?RICA'*,

I ha$e to point out a happening in the #odern !i$ilization of the 'ospital, so#ething %hi!hhappened this year.

"e had to perfor# the first appendi!itis operation on a nati$e of this region. 'o% it turned outthat this so fre+uent si!*ness of %hite people did not o!!ur in the !olored of this !ountry !annot

be !on$in!ingly e<plained. 2robably its still e<!eptional o!!urren!e is tra!eable to a !hange in thenutrition. =any nati$es, espe!ially those %ho are li$ing in larger !o##unities do not no% li$ethe sa#e %ay as for#erlyRthey li$ed al#ost e<!lusi$ely on fruits and $egetables, bananas,!assa$a, igna#, taro, s%eet potatoes and other fruits. They no% begin to li$e on !ondensed #il*,!anned butter, #eat-and-fish preser$es and bread.

The date of the appearan!e of !an!er, another disease of !i$ilization, !annot be tra!ed in ourregion %ith the sa#e !ertainty as that of appendi!itis. "e !annot state de!isi$ely that for#erly



1;7 ee Ei#er, Deutsch. Med. ;o., 19, Ao. (;.1;: ?ro# 2rofessor lbert !h%eitzer&s riefe aus de# 3a#barenespital S3etters fro# the 3a#barene

'ospital8 in fri!a, 19);.

there %as no !an!er at all, be!ause the #i!ros!opi! e<a#inations of all tested tu#ors, re$ealingtheir real nature, has only been in e<isten!e here for a fe% years. ased upon #y o%n e<perien!e,

going ba!* to 191, I !an say, if !an!er o!!urred at all it %as $ery rare but that it be!a#e #orefre+uent sin!e. 'o%e$er, it is not spread as #u!h as it is a#ong the %hite ra!e of Europe and#eri!a.

It is ob$ious to !onne!t the fa!t of in!rease of !an!er %ith the in!reased use of salt by thenati$es. In for#er years there %as only a$ailable the little salt e<tra!ted fro# the o!ean, %hi!h!a#e up to the hinterland. There %as a $ery li#ited traffi! only. The salt had to be transferred bydealers of the tribe li$ing at the !oast to those tribes li$ing ne<t to the# up-strea#. In this %ay itrea!hed one tribe after another and #o$ed further and further to the interior, %here the dealershanded o$er only the portion %hi!h %as left o$er fro# distribution a#ong their o%n tribe andthe !hiefs !harged hea$y !usto#s for the passage through their region. "ith this pro!edure its!ar!ely !ould get farther than 1( #iles inland. !!ording to infor#ation of old people here,

%ho# I still *ne% at the beginning of #y a!ti$ity, for#erly there %as no salt %hatsoe$er in theinterior.

This !hanged in 1:7; %hen the %hites !a#e to this land and handled the traffi! up-strea#. TheEuropean salt %as shipped in s#all sa!*s of a fe% pounds. till at the ti#e of #y arri$al in3a#barene, salt %as so pre!ious that it pre$ailed as the #ost $aluable and the #ost generous typeof re#uneration. "ho e$er had to #a*e a trip on the ri$er or tra$el along the paths of the $irgin%oods did not ta*e along #oney but salt also toba!!o lea$es i#ported fro# #eri!a8, thustrading bananas and !assa$as for his oars#en and !arriers. y and by the !onsu#ption of saltin!reased. Today it is used #u!h less a#ong the !olored than a#ong the %hites. The patients %efeed in our hospital re!ei$e a fe% gra#s a #onth and are satisfied %ith this s#all a#ount.

o it is possible that the for#erly $ery seldo# and still infre+uent o!!urren!e of !an!er in this

!ountry is !onne!ted %ith the for#er $ery little !onsu#ption of salt and the still rare use of it.Curiously enough %e did not ha$e any !an!er !ases in our hospital.

It should be #entioned that the infe!tious diseases a#ong

the %hites gradually appeared. It re#ains +uestionable if tuber!ulosis %as spread for#erly as#u!h as no%, e$en if it o!!urred at all ti#es. !!ording to #y obser$ations it be!a#e #ore fre-+uent after the ?irst "orld "ar.

The e<peri#ents of Pre#er 1;9 ha$e also sho%n !on!lusi$ely that the $alue of sto#a!h a!ids in patients on the diet re#ained nor#al for se$eral #onths, although salt inta*e %as li#ited to salt!ontained in natural food. The appetite of patients does not suffer by la!* of saltO as a rule it e$en

i#pro$es, parti!ularly in serious diseases, after the start of the treat#ent.The eli#ination of a little salt in the s%eat of so#e patients is of no i#portan!e %hate$er in

therapy, for the therapy brings about a fast de!rease and early !o#plete !essation of perspiration.traus !orre!tly attributes this, as %ell as the de!reased #u!us se!retion, to the %ater-%ithdra%ing effe!t of the saltless diet. 'e !on!ludes fro# this that the depri$ation of salt also hasfa$orable therapeuti! effe!ts upon su!h diseases su!h as ron!hogeni!, $aginal dis!harge and

pus se!retions, et!.8.The last argu#ent, that healthy *idneys regulate the ioni! state of the organis# any%ay, and

that it is therefore unne!essary to li#it salt inta*e, is phrased #u!h too generally and does not ta*einto a!!ount i#portant fa!tors apart fro# *idney fun!tion, %hi!h affe!t the eli#ination of AaClhor#ones, tonus in the $is!eral ner$ous syste#, !ir!ulatory regulations8.

The fa!t that diseased *idneys are still !apable of eli#inating fi$e gra#s of AaCl per liter ofurine has no parti!ular #eaning for our proble# regarding the +uantity of salt inta*e. Ae$erthe-less, the !hloride ion deser$es a spe!ial position a#ong the substan!es to be !on!entrated by the



*idneys. "hile the *idneys are !apable of in!reasing !on!entration of uri! substan!e ;-: ti#es,uri! a!id ()-) ti#es, sugar in diabetes8 -) ti#es o$er their !on!entrations in the plas#a,!hloride !on!entration !an be in!reased only t%o to fi$e ti#es14 ?or the past ; years, pra!ti!ale<perien!e %as gathered about the effe!ts of salt li#itation upon diseases of *idneys. It %assho%n 5ust here that radical li#itation of salt inta*e, in the sense of traus& stri!t for# %ith lessthan (.) g of AaCl per day8 or the third degree of Aoorden %ith 1.)- g of AaCl per day8

%hi!h !orresponds to the usual saltless1;9 Med. ;elt, Ao. 1119.1) 3i!ht%itz, @lin. #hemie, 19, p. )1.

T'E 3T3E >IET 141

nutrition, de!reases the burden on the diseased *idneys. s soon as the diseased *idneys are noto$er-irritated and o$er-burdened by the e<!essi$e inta*e of !hlorides in nutrition, they re!o$er inan a#azingly short ti#e and ... eli#inate #ore AaCl on a saltless diet than on the pre$iously salt-ri!h diet1)1

Aoorden also pointed out that su!h saltless nutrition !annot !ure *idney diseaseO the re#o$al ofa !onstant irritation !an only i#pro$e healing !onditions. o#ething si#ilar applies to the effe!tof our diet. The eli#ination of salt does not ser$e to !ure $arious diseases, but it is an i#portantsupporting fa!tor of the diet. da#aging irritation is re#o$ed by the eli#ination of salt.?urther#ore, if the eli#ination of salt by nor#ally fun!tioning *idneys is li#ited by fe$er, as"olff-Eisner points out, and re#ains li#ited in spite of further salt inta*e, this should not lead tothe !on!lusion that the body regulates salt distribution so %ell that physi!ians should lea$e thisfun!tion to the body. This only sho%s that the organis# !annot digest the gi$en +uantities of saltin fe$er states. Therefore, a te#porary radi!al li#itation of salt nutrition fasting, refusal ofnutrition8 is also !orre!t in a!ute diseases infe!tious diseases8. nd, if diseased *idneys !an eli-#inate fi$e gra#s of salt, this does not #ean that fi$e gra#s of salt should be gi$en. /n the!ontrary, it %ould appear to be #ore ob$ious to !on!lude that, by sparing the *idneys and otherorgans, one should try to a!hie$e in all diseases si#ilar results as in *idney-therapy and, lately,

also in heart diseases, !an!er, et!.Claude ernard %as probably one of the first to in$estigate the +uestion of origin of

hydro!hlori! a!id in sto#a!h 5ui!e. 'e in5e!ted potassiu# ferro!yanide and la!tate of iron into the$eins. The substan!es ga$e a 2russian blue rea!tion in the presen!e of free a!id. The #u!osa ofthe sto#a!h turned blue after the in5e!tion but not the parietal !ells of the fundi! glands.

The ulti#ate sour!e of the !hloride is undoubtedly the sodiu# !hloride of the blood. Chloridesare ionized CI in the parietal !ells, se!reted into the sto#a!h&s free spa!eO there they !o#bine%ith free ' ions and built free ' CI %hi!h is not se!reted as su!h. The $enous blood lea$ing thegastri! #u!osa sho%s a fall in !hloride and a rise in bi!arbonate of Aa.

In !on!lusion, it should be stressed that the entire #ineral

Aoorden-alo#on, !andbuch der %rnaehrung, 19(, p. 91.

#etabolis# of the ani#al organis# has not been suffi!iently e<plored so far. Therefore, %e!annot as yet #a*e any definite state#ents about the roles of !hloride and sodiu#Rboth indi-$iduallyRas %ell as in their !o#bination in AaCl and in other !o#binations. "e #ust be !ontent

by establishing !ertain relationships and !onditions in a healthy or a si!* body.

C-APT1R ==II

Salt in Cancer $iet>6 . '/??=A refers to the epo!h-#a*ing resear!h of "ater#an %hi!h thro%s #u!h light on



The ele!tri!al beha$ior of !ells e<posed to salt !hanges in their en$iron#ent. In the polarizationof the !ells under su!h !onditions "ater#an has found a !riterion for the dis!o$ery of the earliest!hanges and the $ery onset of abnor#al pro!esses in the tissue, at a ti#e %hen in all otherrespe!ts the organs appear still perfe!tly nor#al.

!!ording to =eyer, %hen unbalan!ed, the salts be!o#e a sour!e of trouble for !ell#etabolis#. nd that, therefore, it thus be!o#es ob$ious that the *ind of food !onsu#ed and

the regular fun!tioning and !orrelation of all these organs deter#ine in part the +uantity and theratio to one another of the salts present in the seru#.1(

=ineral i#balan!e then be!o#es a +uestion of profound i#portan!e in all dis!ussions of the!ausati$e nature of !an!erous pro!esses. I +uote further fro# =eyer in !onne!tion %ith this+uestion as follo%s

Gi$ing food !redit for that #u!h of a contributory influence to%ard the de$elop#ent of !an!er,al%ays re#e#bering the s#all per!entage of a!tual !an!er !ases a#ong those predisposed, is, of!ourse, $astly different fro# saying that already e<isting !an!er !ould be benefited by spe!ialdiet, a suggestion upon %hi!h %e loo*, in !o##on %ith the great #a5ority of the #edi!al

profession, as ha$ing no standing in #edi!al e<perien!e and no 5ustifi!ation of being #ade the basis for !an!er #edi!ation.

"ith this !on!lusion, ho%e$er, I ?rederi!* 'off#an8 a#1)( /. E. =eyer Gott#gen,19(.

by no #eans in agree#ent. /n the !ontrary I a# of the opinion that the diet of !an!er patients hasa profound effe!t on !an!erous pro!esses %hi!h !an be in!reased or de!reased a!!ording to thefood inta*e and its regulated !he#i!al !o#position.1)

Therapeuti!ally %e find the follo%ing the saltless diet and deto<i!ation redu!e Aa, Cl, '(/ inthe %hole syste#. This is the re#o$al of !ell ede#a si#ultaneously %ith the redu!tion of thenegati$e ele!tri!al potentials. Thus the %ay is pa$ed for the a!ti$ated negati$ely !harged Pgroup #inerals and positi$ely !harged iodine !o#ponents. These !hanges see# to for!e the

!an!er !ells to a higher #etaboli! rate. In #y opinion, the #ineral #etabolis# united, of !ourse,%ith a nu#ber of other re$i$ed pro!esses bring about the de!isi$e role for the death of the !an!er!ells. Can!er !ells !an fer#ent onlyO therefore they are unable to adapt to the ne% intensi$e!hangesRthey brea* do%n and die. This part of the #etabolis# #ust be properly !o#posed and!onstantly rea!ti$ated by the fun!tion of the li$er. Thus, %e #ay assu#e that al#ost all $italfun!tions, fun!tions of the restored #ineral #etabolis#, the deto<i!ation, et!., ne!essary forhealing po%er, are an!hored in the li$er.

o#e authors regarded salt as sti#ulating neoplasti! gro%th and re!o##ended its restri!tion inthe !an!er diet.1); !ontrary opinion %as e<pressed by ?. lu#enthal and E. 'esse in 19), %hosa% that regi#es e<tre#ely poor in salt ha$e a rather unfa$orable influen!e on hu#anneoplasias.

/ther authors found that a protein-poor and P-ri!h regi#e produ!ed fa$orable !onditions fortu#or de$elop#ent, by indu!ing an al*alosis. They e#phasized Ao !an!er %ithout al*alosis.The %ell-*no%n food !he#ist, 6agnar erg,1 ob5e!ted strongly to that $ie%point a diet

produ!ing al*alosis #ay be responsible for the de$elop#ent of !an!er. ll of these opinions stillre#ain in the !ategory of theories.

The a$ailable fa!ts on the role of sodiu# and potassiu# in !an!er are not !lear. The findings ofthe authors and their !on!lusions are, on the %hole, $ery disappointing. =y opinion is that!an!er is not a spe!ifi! disease, has no unifor# sy#pto#s

1) ?rederi!* 3. 'off#an, 3.3.>., #ancer and Diet, The "illia#s "il*ins Co., alti#ore, 197, p.;7. 1); ee op. !it., p. ;1. 1)) Meits!hrift fuer ol*seraaehrung, 9119,19;.

and is not e+ually de$eloped to a !ertain degree. Can!er is an e<traordinary sy#pto# only. Theunderlying !ause is to be found in the poisoning of the li$er. That is #ost probably the reason



%hy the biologi!al findings are in!on!lusi$e and so !ontradi!ting. Can!er is a disease of the li$erlately !alled a balan!e %heel of lifeR%here #ost #etaboli! fun!tions are #ore or less !on!en-trated. ?ro# here the other organs !an be pathologi!ally influen!ed and da#aged or poisoned.#ong the great nu#ber of obser$ations, there are so#e %hi!h see# to be !orre!t but they arenot !onfir#ed by laboratory e<peri#ents. "ater#an found the sodiu# !ontent of blood seru#is un!hanged in !an!er patients. enedi!t and Theis !on!luded that the blood seru# in !an!er

patients !ontains the nor#al a#ount of sodiu#. 2itts and Lohnson e<a#ined the sodiu# !ontentof blood seru# and of blister fluid in !an!erous and non!an!erous patients and dis!o$ered thatthe sodiu# !ontent of these fluids %as the sa#e in !an!er patients and in nor#al patients. >r.?ry des!ribed in the 4ritish #ancer &eview of 19(4 the fa!t that in the blood of tu#or-bearingrats the a#ount of sodiu# is () per !ent abo$e nor#al %hen the tu#or is gro%ing a!ti$ely, and4 per !ent abo$e nor#al %hen the tu#or is re!eding. =ar%ood %ent so far as to say salt is theroot !ause of !an!er.

TAS7 5? T-1 SALTL1SS $I1T I2 CA2C1R The #ain tas* of the saltless diet is to eli#inate the retained Aa, Cl, '(, together %ith to<ins

and poisons fro# the tissues all o$er the body.ll poisons and other substan!es diffi!ult to eli#inate are sti#ulants for the si!* tissues,

espe!ially li$er and *idneys. That !ondition see#s to be the reason %hy sodiu# !hloridee<!retion in!reases in tuber!ulosis, !an!er and other !hroni! diseases after t%o to three days on asaltless diet, and this !ondition stays at that higher le$el for about eight to ten or fourteen days,!orresponding to a fa$orable de$elop#ent in the !ourse of the disease. fter that isa!!o#plished, it stays near the nor#al le$el %ith the saltless diet, but sho%s a higher Aa-Cle<!retion, together %ith #ore fluid fro# ti#e to ti#e for t%o to three days, and later for one day.u!h so-!alled flare-ups go along so#eti#es %ith nausea, diairhea and ner$ous disturban!es,!aused probably by greater bile se!retion and sti#ulation of the $is!eral ner$ous syste#. fterea!h flare-up the patient feels easier and #entally i#pro$ed.

<ndications for 'altless Diet

a8 Ede#a and abnor#al deposition of sodiu# and !hloride inthe sub!utaneous tissue nephropathies8, b8 Cardio-renal insuffi!ien!y, !8 P-Ioss

and Aa-retention, in !hroni! diseases, espe!ially intuber!ulosis, !an!er, et!.

d8 >eto<i!ation, the degree of %hi!h #ust be in proportion tothe degree of the disease-and %hi!h #ust be #aintainedduring the period of restoration.

C-APT1R ==III

Insecticides

"E 'E learned in re!ent years that spraying %ith #odern inse!ti!ides is doing #ore and #oreda#age to our food and toour bodies. I !annot e#phasize too often that our food produ!tion represents our e<ternal#etabolis#. "hoe$er is interested in this field #ay read the !earings 4efore the !ouse 'elect

#ommittee to <nvestigate the 6se of #hemicals in 7ood Products, !ouse of &epresentatives %ighty97irst #ongress, 'econd 'ession. *) There is !learly des!ribed in the hearing of >r.is*ind %hat he obser$ed in this field and %hat he re!o##ended ought to be done.



The follo%ing is a brief sur$ey of this hearing The introdu!tion for un!ontrolled general use by the publi! of the inse!ti!ide >>T, or !hlorophenothane, and the series of e$en #ore deadlysubstan!es that follo%ed, has no pre$ious !ounterpart in history. eyond +uestion, no othersubstan!e *no%n to #an %as e$er before de$eloped so rapidly and spread indis!ri#inately o$erso large a portion of the earth in so short a ti#e. This is the #ore surprising as, at the ti#e >>T%as released for publi! use, a large a#ount of data %as already a$ailable in the #edi!al literature

sho%ing that this agent %as e<tre#ely to<i! for #any different spe!ies of ani#als, that it %as!u#ulati$ely stored in the body fat and that it appeared in the #il*. t this ti#e a fe% !ases of>>T poisoning in hu#an beings had also been reported. These obser$ations %ere al#ost!o#pletely ignored or #isinterpreted.

In the subse+uent #ass use of >>T and related !o#pounds a $ast a#ount of additionalinfor#ation on the to<i!ity of these #aterials, both in ani#als and in #an, has be!o#e a$ailable.

1)4 Created 2ursuant to '. 6es. ( 6eprint _(-)( 3ee ?oundation for Autritional 6esear!h,=il%au*ee , "is!onsin8.

o#eho% a fantasti! #yth of hu#an in$ulnerability has gro%n up %ith referen!e to the use of

these substan!es. e!ause their effe!ts are !u#ulati$e and #ay be insidious and be!ause theyrese#ble those of so #any other !onditions, physi!ians for the #ost part ha$e been una%are ofthe danger. Else%here, the e$iden!e has been treated %ith disbelief, ignored, #isinterpreted,distorted, suppressed or sub5e!ted to so#e of the fan!iest double-tal* e$er perpetrated.

Early last year I published a series of obser$ations on >>T poisoning in #an. in!e shortlyafter the last %ar a large nu#ber of !ases had been obser$ed by physi!ians all o$er the !ountry in%hi!h a group of sy#pto#s o!!urred, the #ost pro#inent feature of %hi!h %as gastroenteritis,

persistently re!urrent ner$ous sy#pto#s, and e<tre#e #us!ular %ea*ness. The !ondition %as ofun*no%n origin and, follo%ing an outbrea* in 3os ngeles in 19;7, %as thereafter %idelyattributed to a $irus N. s %ith all other physi!ians, a large nu#ber of #y patients had this!ondition.

I, li*e others, found it e<tre#ely puzzlingO it rese#bled no infe!tious pro!ess I %as a!+uainted%ith, and it had features strongly suggesting so#e *ind of into<i!ation. I had *no%n that >>T%as far #ore to<i! than !urrent #ythology ad#itted, but it %as only %hen I !a#e a!ross an ite#in the literature indi!ating the $ast a#ount of >>T already in use in our agri!ultural e!ono#y thatthe possibility that this agent %as in$ol$ed o!!urred to #e. I i##ediately !onsulted a$ailablete<tboo*s and found that the signs and sy#pto#s of *no%n >>T poisoning %ere suffi!ientlysi#ilar to the !ases I had seen to %arrant further in$estigation. In fa!t, in 19;) t%o ritishauthors had des!ribed %ith great a!!ura!y part of the disorder follo%ing e<posure to >>T inthree hu#an sub5e!ts.

The syndro#e !onsists of a group of or all of the follo%ing !ute gastroenteritis o!!urs, %ithnausea, $o#iting, abdo#inal pain, and diarrhea. running nose, !ough, and persistent sorethroat are !o##on, often follo%ed by a persistent or re!urrent feeling of !onstri!tion or a lu#p inthe throat o!!asionally the sensation of !onstri!tion e<tends into the !hest and to the ba!* andshoulders and #ay be asso!iated %ith se$ere pain in either ar# and #ay easily be !onfused %itha heart or gall-bladder atta!*. 2ain in the 5oints, general #us!le %ea*ness, and e<hausting fatigueare usualO the latter are often so se$ere in the a!ute stage as to be des!ribed by so#e patients as

paralysis. o#eti#es the initial atta!* is ushered in by dizziness and fainting. Inso#nia,intra!table heada!he, and giddiness are not un!o##on. >isturbed sensations of $arious *indso!!ur in #ost !asesO areas of s*in be!o#e e<+uisitely hypersensiti$e and after a fe% days thisdisappears, only to re!ur else%here, or irregular nu#bness, tingling sensations, it!hing or!ra%ling sensations, or a feeling of lo!alized heat #ay ta*e pla!e. Errati! t%it!hing of $oluntary

#us!les is !o##on. @sually there is di#inution of ability to feel $ibration in the e<tre#ities. 3ossof %eight is not un!o##on.>isturban!es of e+uilibriu# #ay o!!ur. There #ay be atta!*s of rapid pulse and palpitation

asso!iated %ith !ontra!tion of blood $essels in the s*in, s%eating of the pal#s and a sense of



i#pending loss of !ons!iousness, follo%ed by slo% pulse, flushing of the s*in, rela<ation and!essation of pal#ar perspiration.

The sub5e!ti$e rea!tions tend to re!ur in &%a$es,& as nu#erous patients ha$e des!ribed the#.o#e ha$e a!tually been able to !lo!* the rea!tion %ith !onsiderable pre!ision fro# day to day.The rea!tions appear #ost li*ely to o!!ur during periods of lo% blood sugar. dditionally,!onsu#ption of al!oholi! be$erages or a!ute e#otional stress #ay pro$o*e a se$ere

e<a!erbation./ften, patients %ith this disorder !o#plain of a hollo% feeling in the epigastriu# %hi!h

bears no !onstant !hronologi! relation to the ingestion of food, and in fa!t #ay ta*e pla!ei##ediately after a full #eal. tte#pts to eat further #ay pro$o*e sharp repugnan!e for foodand o!!asionally #ay lead to an atta!* of hi!!ups or nausea. In other patients, a!tual o$ereatingindistinguishable fro# the !o#pulsi$e types seen in !ertain psy!hogeni! disturban!es #ay result.

'ardly a single sensory ner$e appears to be i##une to in$ol$e#ent in this disorder disordersof $ision, s#ell, taste and hearing #ay o!!ur. 2ain of $arying intensity and duration #ay in$ol$eany area of the s*in and #ay lo!alize in a 5oint or e$en in a tooth. e$ere peripheral neuritisin$ol$ing intense, protra!ted pain in one or #ore of the e<tre#ities is fre+uent. 2ain in the groin,usually bilateral, is a fre+uent !o#plaint. In the a!ute stages, #ild !on$ulsions in$ol$ing #ainly

the legs, #ay o!!ur.fter subsiden!e of the a!ute atta!*, irregular spas# throughout the gastrointestinal tra!t often

persists for %ee*s or #onths asso!iated %ith in!reased fatiguability, %hi!h only gradually re-gresses. ?e$er o!!urs o!!asionally during the initial stages but is not the rule. E<!ept for atenden!y for ane#ia, and in so#e !ases a relati$e in!rease in !ertain %hite blood !ells, no!onstant !hanges are obser$able in the blood. =any of the patients ha$e an a!ute bout ofapprehension asso!iated %ith the foregoing sy#pto# !o#ple< and rarely is this relie$ed byreassuran!e as to the absen!e of physi!al findings suffi!ient to a!!ount for the se$erity of thedisturban!e.

=ost stri*ing about the syndro#e is the persisten!e of so#e of the sy#pto#s, the tenden!y torepeated re!urren!e of others o$er a period of #any #onthsRso#e patients fail to sho% !o#-

plete re!o$ery e$en after a yearRand the la!* of dete!table lesions suffi!ient to a!!ount for these$erity of the sub5e!ti$e rea!tion.

The high in!iden!e, the usual absen!e of a febrile rea!tion, the persisten!e and errati!re!urren!e of the sy#pto#s, the la!* of obser$able infla##atory lesions, and the resistan!ee$en to palliati$e therapy, as I ha$e already indi!ated, suggested an into<i!ation rather than aninfe!tion. The epide#i! first appeared at about the ti#e >>T !a#e into %idespread use by the!i$ilian population. The signs and sy#pto#s des!ribed in the phar#a!ologi! and to<ilogi!literature as !hara!teristi! of >>T poisoning turned out to be identi!al %ith those appearing in

patients %ith the affli!tion des!ribed.y far the #ost disturbing of all the #anifestations are the sub5e!ti$e rea!tions and the

extreme muscular weakness. In the se$ere, a!ute !ases, patient after patient has used identi!al%ords, 1 felt li*e I %as going to die.&I found si#ilar des!riptions in reading about the so-!alled &I!eland disease,& the #ost

!hara!teristi! sy#pto# of %hi!h is e<tre#e #us!ular %ea*ness, %hi!h begins in the legs, thenspreads to both ar#s and handsO patients e$en ha$e diffi!ulty in s%allo%ing. 8"ewsweek, =ay19)78

The sensation !an perhaps best be des!ribed as one of unbearable e#otional turbulen!e. Thereare at $arious ti#es e<!ite#ent, hyper-irritability, an<iety, !onfusion, inability to !on!entrate,inattenti$eness, forgetfulness, depression, and espe!ially e<tre#e apprehensi$eness. Theseepisodes !an easily be !onfused %ith an<iety atta!*s ha$ing a psy!hiatri! basis. The !o#binationof apprehensi$eness, !onfusion, and depression has led to sui!idal i#pulses in a nu#ber of #y

patients. e$eral insisted after a %ee* or t%o of a #ore or less !ontinuous disturban!e that theydid not %ant to li$e if the rea!tion persisted. This rea!tion %as the #ore diffi!ult to bear be!auseits sour!e %as un*no%n and, %hen the !ause be!a#e apparent, e<planation as to the etiology



%as usually of great help in tiding the patient o$er this diffi!ult period. /ne su!h patient %hohad been hea$ily e<posed to >>T %as treated psy!hiatri!ally for his sui!idal depression for#onths %ithout su!!ess. This depression $anished %ithin a fe% %ee*s %hen e<posure to >>T%as redu!ed to a #ini#u# by re#o$ing it fro# the i##ediate en$iron#ent and restri!ting thefoods #ost hea$ily !onta#inated. 2arentheti!ally, one !annot help but %onder ho% oftene<posure to the >>T group of !o#pounds has been i#pli!ated in other%ise ine<pli!able

sui!ides. Certainly in a person already #entally disturbed the additional stress of >>T poisoning!ould be disastrous. In addition, the #ental effe!ts of >>T #ay easily lead to a!!idents.

!hara!teristi! history is that of a personRand in a nu#ber of !ases, an entire fa#ilysi#ultaneously in$ol$edR%ho, pre$iously %ell and able to #a*e satisfa!tory e#otionalad5ust#ent to his en$iron#ent, suddenly is affe!ted %ith the syndro#e des!ribed and re#ains

partially disabled for #any #onths. @sually, the !ondition re#ains undiagnosed and fre+uentlythese patients #a*e the rounds of do!tor after do!tor and institution after institution see*ing atleast a diagnosis, if not relief. The e<tent to %hi!h this !an go is illustrated in the !ase of ane<ter#inator %ho had used both >>T and !hlordane.

t the ti#e I first sa% this patient he had spent t%o and one-half years $isiting $arious physi!ians and institutions see*ing relief fro# his disabling sy#pto#s, %hi!h !onsisted of pain

and sense of !onstri!tion in the throat and !hest, irregular heada!hes, and pain in his head, ne!*,and shoulders, #us!ular t%it!hing all o$er his body, inso#nia, inability to !on!entrate,forgetfulness and inattenti$eness, disturbing sensations in $arious parts of the s*in, repeatedgastroenteritis and re!urrent e<tre#e #us!ular %ea*ness. In the pro!ess of see*ing a diagnosishe as*ed do!tor after do!tor %hether the inse!ti!ides %ere responsible for his ail#ent and %asrepeatedly assured they !ould not be. 'e %as sub5e!ted to $irtually e$ery test *no%n to #edi!als!ien!e and e$en had his s*ull opened for in5e!tion of air into his !erebral $entri!les for N-ray

purposes to #a*e sure he had no brain tu#or. Aone of the #any tests and e<a#inations !oulda!!ount for his sy#pto#s. ?inally one of the psy!hiatrists to %ho# he %as referred re!ognizedthe ail#ent as ha$ing a to<i! basis.

"hen I sa% the patient he had an enlarged li$er, signs of nutritional i#pair#ent, redu!edability to feel $ibration in his legs and a redu!tion in his pulse pressure. @nder ordinary !ir-!u#stan!es none of these signs, nor all together, !ould a!!ount for all his sy#pto#s. "hen he%as ad$ised to gi$e up his 5ob and see* less to<i! e#ploy#ent, to re#o$e all tra!es of >>T and!hlordane fro# his en$iron#ent, %as gi$en nutritional therapy to alle$iate the li$er da#age and

put on a diet lo% in inse!ti!ide residues, he sho%ed pro#pt i#pro$e#ent %ithin a %ee*. ?our#onths later he %as al#ost free of sy#pto#s. 'e %as then un*no%ingly e<posed to >>T in arestaurant *it!hen %hi!h had 5ust pre$iously been aerosoled %ith >>T. "ithin half an hour theentire syndro#e returned and re+uired #ore than a %ee* to subside.

gain, t%o #onths later he %as inad$ertently e<posed to !hlordane fro# an old *it he had pre$iously used. This ti#e there %as a $ery se$ere e<a!erbation %hi!h re+uired nearly t%o

#onths for subsiden!e. ?ortunately, this patient no% is al#ost !o#pletely %ell for the first ti#esin!e 19;7.The sy#pto# of an enlarged li$er is +uite non-!hara!teristi! as %e see it in #any a!ute and

infe!tious diseases, as %ell as in degenerati$e diseases, in!luding !an!er. I had not yet had theopportunity to study all different poisons present in a !an!er body %here they produ!e thedestru!ti$e %or* #ost stri*ingly e<pressed in the li$er, the $is!eral ner$ous syste# and the!ir!ulatory apparatus, parti!ularly the !apillaries. These are 5ust the organs needed for healing

purposes.Espe!ially interesting is an obser$ation #ade in England. "hen %heat %as #illed about one-

third of the >>T residue %as found in the flour thus sho%ing that the inse!ti!ide had +ui!*ly penetrated the grain hus*s. 6ats fed %ith the bread #ade fro# this flour, li*e hens fed %ith the

un#illed grain, sho%ed %ide and rapid distribution of the inse!ti!ide in their bodies."e are espe!ially interested here in the proble# that, in asso!iation %ith li$er da#age, there

often is an in!reased fragi-bility of the %alls of the s#all blood $essels and the !apillaries.



3ater they #ay ha$e a tenden!y to rupture easily. >r. ?. =. 2ottenger in California hasrepeatedly obser$ed a rise in blood !holesterol in hu#an beings, #ore fre+uently than he e$ersa% before. 'e has seen that syndro#e in about one-third of his patients and assu#ed that it #ay

be !aused by >>T poisoning of the li$er. E$en if #ost of these obser$ations are the personal%or* of >r. is*ind, they are partly !onfir#ed by a fe% other !lini!al %or*ers in this field.

"hat has been done to date to pre$ent these unfa$orable !onse+uen!es, is not $ery

en!ouraging. n arti!le in the "ew =ork Times, ?ebruary 1, 19)(, stated that the ee!hnut2a!*ing Co#pany spent about ^44:, in the past si< years to *eep residues of ne% pesti!idesout of baby food and peanut butter. I hope that in the follo%ing years #ore substantial and!riti!al %or* %ill be done in this dire!tion.

C-APT1R ==I.

The Significance of the Content of the Soil to -uman

$iseaseT'E ?=I3I6 e<pression #other earth is 5ustified. "hen %e ta*e fro# and rob the earth %e

disturb the natural e+uilibriu# and har#ony, produ!ing si!*ness of the soil, si!*ness of the plants and fruits Sthe !o##on nutrition8, and finally si!*ness of both ani#als and hu#an beings.

s a physi!ian %ho has spent #u!h of his life in$estigating the nutritional aspe!ts of disease, Iha$e often had o!!asion to obser$e a definite !onne!tion bet%een dietary defi!ien!ies anddiseases, and bet%een dietary defi!ien!ies and a si!* or poor +uality soil.

The relationship bet%een soil and plants on the one hand and ani#al and hu#an nutrition onthe other is to #e a fas!inating sub5e!t. This relationship is a natural !y!le in %hi!h one #aydistinguish t%o great parts

I. The first part, %hi!h #ay be !alled e<ternal #etabolis#, is !o#prised of the follo%ing

a8 2lants and their fruits.

b8 Co#position of the soil in %hi!h they gro%Rthus being the real basis of all nutrition.!8 Transportation, storage and preparation of these foodstuffs.

II. The se!ond part, *no%n as internal #etabolis#, !onsists of all the bio!he#i!altransfor#ations that ta*e pla!e %hen su!h foodstuffs enter the ani#al body and support thenutrition and gro%th of its !ells and tissues.

"hen foodstuffs are ingested, their #etabolis# is influen!ed dire!tly by the bio!he#i!al!hanges of the indi$idual body and indire!tly by the !ondition of the soil fro# %hi!h they !a#e.The type of #etaboli! !hange thus dire!tly affe!ts the nutrition and gro%th of the body tissues.There is an e<ternal and an internal #etabolis# upon %hi!h all life dependsO both are !losely and

ine<tri!ably !onne!ted %ith ea!h otherO further#ore, the reser$es of both are not ine<haustible.There are, of !ourse, so#e e<!eptions, about fi$e to ten per !ent of the population %ho ha$e ane<traordinarily %ell-fun!tioning reabsorption and good storage !apa!ity apparatus.

This is to e#phasize the great i#portan!e of #etabolis# to hu#an health, i.e., the soil as the basis of life %hi!h is generally negle!ted to a great e<tent.

I thin* it %as !orre!t for the >epart#ent of gri!ulture to ha$e gi$en its 19: yearboo* theshort but e<pressi$e title oils and =en, and that of the 199 yearboo*, ?ood and 3ife. "e#ay !o#pare the %or* of the soil to a #other feeding her baby.



C. . ro%ne stated that the plant is the great inter#ediary by %hi!h !ertain ele#ents of thero!*s, after their !on$ersion into soil, are assi#ilated and #ade a$ailable for the $ital pro!essesof ani#als and #an. The si#ple inorgani! !onstituents of the at#osphere and soil are sele!tedand built up by the plants into protein, sugar, star!h, fat, organi! salts and other substan!es of

#ar$elous !o#ple<ity.1)7

Table 1 %ill gi$e the reader a good pi!ture of the great losses in #ineral nutrients sustained bysoils as a result of !ropping and lea!hing. The a#ount of #inerals dissol$ed ea!h year fro# thesoils of the drainage basis of four #eri!an ri$ers has been esti#ated by Clar*e to a$erage 79.4tons annually per s+uare #ile.

This table sho%s the soil needs a!ti$ity, the natural !y!le of gro%th, rest and return of %aste to#aintain its produ!ti$ityRits life. "e #ust not only ta*e, but also gi$e ba!* nitri! a!id and

potassiu#.

The first part of this table #a*es it !lear that the stra% of oats sho%s a redu!tion of potash toless than a third in ten years, %hile the %hole plant of bu!*%heat s!ar!ely sho%s any differen!e in



si< years, sin!e lea$es and blosso#s !annot thri$e %ithout suffi!ient potassiu#.

/ther%ise, %ith P defi!ien!y %e open the door to a!ute and !hroni! diseases. The #aintenan!eof P-pre$alen!e 4 per !ent in the #ost essential organs8 is $ery i#portant in plants, in ani#alsand #en.

That defi!ien!ies in #inerals of the soil produ!e so#e !orresponding si!*nesses on plants %as%or*ed out %ith great endea$or. 3iebig&s la% of the #ini#u# that the defi!ien!y of onenutrient in the soil %ill retard the assi#ilation of other nutrients by plants, !ould not be#aintained, as later e<peri#ents re$ealed.

/ne of the #ost interesting parts of #odern resear!h in soil, plant and ani#al nutrition is thatso#e tra!e ele#entsR!opper, #anganese, !obalt, iron, iodine, boron, and zin!Rare ne!essaryin parts per #illion, i.e., $ery tiny a#ountsRyet %ithout these tra!e ele#ents, plants and ani#alssuffer fro# serious diseases. Iodine is uni+ue a#ong these tra!e ele#ents as its defi!ien!y has nodire!t effe!t on the plant itselfO e<peri#ents sho% the sa#e gro%th and the sa#e yield on or ;generations %ith or %ithout iodine, but the follo%ing generations sho%ed a signifi!ant de!reasein !rop. These e<peri#ents %ere done by 2rof. ?al* and #yself.8 "e did not find anye<planation in the obser$ations of others about the detri#ental effe!t on #an and do#esti!ani#als.



T$4% A<< R The minor9element content of some important crops in 7luorine This table is

added to show the fluorine content of fruits and vegetables, thus proving that additional

fluoridation of %afer is unne!essaryRand !an be harmful. "ature uses fluorine inminimum doses in the skin to !o$er and protect fruits like cherries, peaches, apples, apri9

cots, potatoes, beets, etc. Ralso in the enamel of our teeth.



The birth of hairless pigs has been !aused e<peri#entally by feeding brood so%s diets lo% iniodine and has been pre$ented by supplying iodine !o#pounds, seen i##ediately in tiefollo%ing generationsO but, iron in #i!e ta*es effe!t in the fifth or si<th generation only. Thissho%s at the sa#e ti#e that so#e of the defi!ien!ies are transferred to the follo%ing or later

generations by nature Rthrough the fertilization apparatus the egg or sper#atozoonR as thereis no other %ay.?a#iliar e<a#ples of the results of a defi!ien!y of tra!e #inerals are

a8 'and drawn of tobacco, due to #agnesiu# defi!ien!y if the soil !ontains less than .(Z=g/.

b8 #hlorosis of tomatoes on ?lorida soils, %hi!h !an be !ured by #anganese additions.!8 The wilting of leaves in tobacco is !aused by !opper defi!ien!y.d8 7ailure of cattle to develop normally is often due to defi!ien!y of iron, !opper or possibly

!obalt in plants. Iron dire!tly !onne!ted to !hlorophyll.8e8 The abnormal accumulated occurrence of animal and human goitre in parts of

%itzerland, "is!onsin, =innesota and "ashington is due to iodine defi!ien!y.

f8 3a#e-si!*ness of !attle in outh fri!a is due to defi!ien!y of Ca. P. 2. in lea!hedareas.

g8 ush si!*ness of sheep in Ae% Mealand is due to la!* of !obalt. h8 'airless pigs due to iodine defi!ien!y. i8 In hu#an beings so#e a!ute and!hroni! diseases are due to the follo%ing defi!ien!ies

ad teeth, to P and Ca6i!*ets, to Ca and 2ne#ias, to !opper and iron=yede#a and goitre, to iodinetar$ation ede#a, nephriti! ede#a, !ardia! ede#a, !ardiorenal syndro#e, old age thyroid

defi!ien!y8, et!., all #ore or less due to defi!ien!y of se$eral #inerals*in and bone tuber!ulosis, to P. 2. Ca, et!.

max gerson - a cancer therapy results of fifty cases part 1.doc

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