maternity drugs
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Labor and Delivery Unit DrugsDrug Rout
e ofAdm
in
NursingResp.
Contra Mechanismof action
Side eects Class
!hytonadione in".#$it%&
injection Avoid IM inj;use softtoothbrush;reportsymptoms ofbleeding;teach abouttheimportance of
frequent labtests
Hypersensitivity, severehepaticdisease, lastfew weeks ofpregnancy
eeded foradequate bloodclotting !factorsII, "II, I#,#$
#CNS&HA, braindamage#'(&nausea,decreased %&'s#)*MA&hemolyticanemia,hemoglobinuria,hyperbilirubinemia#(N+*'&rash, uticaria
#R*S!&bronchospasm,dyspnea, feeling ofchest constriction, resparrest
"it (; fat)solublevitamin
Cytotec#Misoprostol
&,
*+ o not take ifpregnant; donot take formore than -wks unlessdirected;
avoid +'.preparations/aspirin,cough, coldproducts,condition mayworsen
Hypersensitivity to thisproduct orprostaglandins;*regnancy !#$
Inhibits gastricacid secretion;may protectgastric mucosa;can increasebicarbonate,
mucusproduction
#'(&diarrhea, 0",1atulence,constipation,dyspepsia, abdominalpain#'U&spotting, cramps,
hypermenorrhea,menstrual d0os
2astricmucosaprotectant;antiulcer
Duramorph
inj Allergy to otheropiates, acutebronchial
asthma, upper
*ain relief Hypotension, respdepression and0or resparrest; pruritus, urinary
retention, constipation,
opium
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#forintrathecalin".&
airwayobstruction
HA
-entanyl
'rans)
dermalasalspray3% sprayInj
About .3
changes,physicaldependence,not to usewith alcoholor other .3depressants!transdermal$e4cessiveheat mayincreaseabsorption
Hypersensitivit
y to opiates,myastheniagravis;*regnancy 5
Inhibits
ascending painpathways in.3, increasespain threshold,alters painperception bybinding toopiatereceptors
#CNS&di66iness,
delirium, euphoria,sedation#C$&bradycardia,arrest,hypo0hypertension#**N+&blurred vision,miosis#'(&0", constipation#gu&urinary retention#(N+*'&rash,diaphoresis#MS&muscle rigidity#R*S!&respdepression, arrest,laryngospasm
+pioid
analgesic
MagnesiumSulfate ($,
I",irectI",.ontinuous I"I&route
ot for long)term; chillingimprovestaste; shakesuspension;not to give atbedtime; givecitris fruiteafter tocounteracttaste;e4pectedresults
Hypersensitivity, abdominalpain, 0",obstruction,acute surgicalabdomen,rectal bleeding,heart block,myocardialdamage
Inreasesosmoticpressure, draws1uid into colon,neutrali6es H.l
#CNS&muscleweakness, 1ushing,sweating, confusion,sedation, depressedre1e4es, 1accidparalysis, hypothermia#C$&hypotension,heart block, circulatorycollapse, vasodilation#'(&0", anore4ia,cramps, diarrhea#)*MA&prolongedbleeding time#M*+A&electrolyte,1uid imbalances
7lectrolyte; anti)convulsant; salinela4ative;antacid
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#R*S!&respdepression
!enicillin '
($!/,
I" .arry I ifallergic, shakesusp well;report sore
throat, fever,fatigue; reportdiarrhea
Hypersensitivity to penicillin,corn;pregnancy !8$
Intereferes withcell)wallreplication ofsusceptible
organisms; incell death
#CNS&lethargy,hallucinations,depression, twitching#'(&0" diarrhea
#'U&vaginitis,moniliasis#M*+A&alkalosis,hypernathypo0hyperkalemia#M(SC&local pain
8road)spectrumanti)infective
/etamethasone (M#Celestone&
IM otify if youare taking+'.s or othermedications;may interferewith vaccines;may need tobe on a salt)restriction dietor take (9supplements
ecreasesin1ammation
8lack0tarry stools;blurred vision; bluishskin; unusual bleedingor bruising; muscleweakness0cramps;sudden0severestomach pain, n0v
.ortico)steroid
Cervidil#Dinoproston
"ag sup;2el!pre:lledsyringe$;"aginsert
emainsupine for
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e& intercourse,tub baths,douches,tampon usefor at least ?wks
#(N+*'&rash, skincolor changes#MS& leg cramps, jointswelling, weakness#'*L&uterinecontractile
abnormality, back pain,fever#(NS*R+&uterinehyperstimulation,fever, 0", diarrhea,abdominal pain#SU!!1S(+1R0&uterine rupture,anaphyla4is
*phedrineSulfate,
InjsubcutIMI"
Angle closureglaucoma; ifvasopressordrugs may becontraindicated
ervousness, an4iety,di66iness, HA, 0", lossof appetite, or troublesleeping
8roncho)dilator
)emabate
InjIM
*ossiblecervicaltrauma
Indices abortion *elvic pain, cramping,vaginal bleeding; highfever; light)headedness or 3+8;0" diarrhea; increased8*
o4ytocic
Nubain#Nalbuphine&
I"38.'IM
eport .3changes,physicaldependencycan resultwith long termuse;withdrawalsymptoms
Addiction;pregnany !.$
epresses painimplsetransmission atthe spinal cordlevel byinteracting withopioidreceptors
#CNS&drowsiness,di66iness, confusion,HA, sedation, euphoria#C$&palpatations,bradycardia, change inbp#**N+&tinnitus,blurred vision#'(&0" anore4ia,
+pioidanalgesic
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may occur;avoid .3depressants07
'+H
constipation, cramps#'U&increased urinaryoutput, urinaryretention#(N+*'&rash#R*S!&resp
depression
+erbutaline#/rethine&
inhalant o smoking;up 1uids byB? %0day;allow minsbtwninhalation ofproduct Cinhaledproduct
containingsteroid; ifmissed, not tomake up after< hr, to waituntil ne4tdose
Hypersensitivity tosympathomimetic, closedangleglaucoma,tachydysrthymias
ela4esbronchialsmooth muscle;bronchodilation, diuresis,; .3,cardiacstimulationoccur; rela4esuterine smooth
muscle
#CNS&tremors,an4iety, insomnia, HA,di66iness, stimulation#C$&palpitations,tachycardia, H',dysrhythmias#'(&0"#M*+A&hypokalemia,hyperglycemia
#R*S!¶do4icalbronchospasm,dyspnea
3elective8?)agonist;broncho)dilator
/upivacaine#forintrathecalin".&
inj Alert if youhave asthma,diabetes,liver, kidney,heart disease,sei6ures, M2,thyroidproblems,circulations,hypo0H'
May preventpain
Aniety, depression,tinnitus, blurred vision,chest pain, fast,pounding, slow, oruneven heartbeat,trouble breathing, 0",chills, sei6ures
%ocalanesthetic
IMI"
eportincreasedblood loss,
3erum to4emia,cephalopelvicdisproportion,
Acts directly onmyo:btils,thereby
#CNS&sei6ures, tetaniccontractions#C$&hypo0H'
hormone
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12ytocin#!itocin for(1L&,
abdominalcramps,feverl, foulsmellinglochia;contractions
will be similarto menstrualcramps,graduallyincreasing inintensity
fetal distress,hypertonicuterus;prolapsedumbilical cord;active gential
herpes
producinguterinecontraction;stimulates milkejection;vasoactive
antidiureticeDect
#-*+US&dysrhythmias,
jaundice, hypo4ia#'(&anore4ia, 0",constipation#'U&abrupto
placentae, decreaseduterine blood 1ow#)*MA&hyperbilirubinemia#(N+*'&rash
*rythromycin
ophthalmicoint.,
ointment
otify ofdiarrheastools, darkurine, pale
stools,jaundice ofeyes or skin
*ree4istinghepaticdisease;*regnancy !8$
8inds to >=3ribosomalsubuniys ofsusceptible
bacteria andsuppressesproteinsynthesis
#CNS& sie6ures#C$&dusrhythmias, E'prolongation#**N+&hearing loss,
tinnitus#'(& 0" diarrhea#'U& vaginitismoniliasis#(N+*'& rash
Anti)infective
)epatitis /$accine,
inj eport rash,whee6ing,inability tobreathe
.oagulationd0os; *regnancy! .$
*rovidespassiveimmunity toHep 8
#CNS& HA, di66iness,fever#'(& 0"#(N+*'&swelling
Immuneglobulin
LidocaineInjsolution
(nown historyofhypersensitivityto localanesthetics
*revent pain neven heartbeats;drowsiness0confusion;tremors, sei6ures;blurred vision
%ocalanesthetic
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"accine/
"icodin
Infantliquid
'ylenol/