Marsel Mesulam, MD

NORTHWESTERN UNIVERSITY FEINBERG SCHOOL OF MEDICINE

SOURCE OF CONFUSION

•bvFTD and PPA are major syndromes of FTLD.

•However, in a minority of cases they can be caused by AD.

QUIZ1. ARE PPA AND bvFTD MAJOR CLINICAL SYNDROMES OF FTLD?

2. ARE PPA AND bvFTD ALWAYS CAUSED BY FTLD?

3. IS PPA OR bvFTD A MAJOR CLINICAL SYNDROME OF ALZHEIMER'S DISEASE?

4. CAN PPA OR bvFTD BE CAUSED BY ALZHEIMER'S DISEASE?

YES

NO

NO

YES

B

W

STG

MTG

M1 S1

Rogalski, Cobia, Wieneke, Weintraub, Mesulam- SFN 2009

FDR 0.01 FDR 0.015

A1

V1

Left hemisphere Right hemisphere

ppaconnection.org