Department of PediatricsDivision of Pediatric NephrologyP.O. Box 016960 (M-714)Miami, Florida 33101

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PAIDMiami, FL

Permit No. 438

MIAMI PEDIATRIC NEPHROLOGY 44TH YEAR SEMINARMarch 2 - March 5, 2017The Alexander All Suite Ocean Front ResortMiami Beach, Florida

Sponsored by the

Presented by the Division of Pediatric Nephrology, Department of Pediatrics and the Division of Renal Pathology, Department of Pathology

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44th mIamI PedIatrIc nePHrology SemInar and 4tH renal PatHology courSe

MARCH 2 - 5, 2017

For More Information call 305-243-6716Visit us at http://pediatrics.med.miami.edu/nephrology/seminar

MIAMI BEACH, FL The Alexander

ALL SUITE OCEAN FRONT RESORT5225 Collins Avenue • Miami Beach, FL 33140

PROGRAM DIRECTOR: Gastón Zilleruelo, M.D. ASSOCIATE PROGRAM DIRECTORS:

Carolyn L. Abitbol, M.D. and Michael Freundlich, M.D.FOUNDED BY: José Strauss, M.D.

COURSE DESCRIPTIONThe Miami Pediatric Nephrology Seminar now in its 44th year is an unique international gathering of pediatric and adult nephrologists, pediatricians, internists, general practitioners, renal pathologists, neonatologists, pediatric urologists, transplant surgeons, nurses, nutritionists and allied health professionals from all over the United States and the world sponsored by the University of Miami, Leonard Miller School of Medicine and Holtz Children’s Hospital at Jackson Memorial Hospital. The content is basic, the approach is clinical. Conceptual and practical problems are featured in a balance of formal presentations followed by informal discussions. Topics covered relate research advances to the understanding of mechanisms of renal disease, pathological expressions and clinical diagnosis and management. All registrants have opportunities to be involved in a dynamic exchange of information, experience, and insight. Selection of topics, faculty and format are based on suggestions from past Seminar participants and current questions. The 44th Pediatric Nephrology Seminar and the preceding Renal Pathology Course will include a total of 12 Sessions from March 2-5, 2017. The Pre-Seminar Renal Pathology Course is an intensive, one and half day comprehensive course covering all aspects of nephro-pathology starting with sample processing and transition to glomerular, tubular, cystic as well as systemic and metabolic disorders affecting pediatric and young adult patients finalizing with a clinico-pathologic correlations interactive Session. The Pediatric Nephrology Seminar will cover a wide range of topics including The Kidney of the Neonate, Genetics for the Clinician, Clinico - Pathologic Correlations, Cardiovascular-Kidney Interactions in CKD, Innovative Concepts and Therapies in Glomerular Disorders, Nutrition and Growth in CKD (Workshop), Dialysis/CRRT and Transplant Challenges. In addition, there will be an optional “hands-on” Workshop dealing with CRRT and Critical Care Pediatric Nephrology at the end of the Seminar specifically developed for physicians in-training. All the topics selected have high clinical research relevance and have not been covered in this format by other conferences in recent years. The Seminar will feature 28 distinguished Guest Faculty and 21 Local Faculty who will provide expertise and cordial exchanges including several panel discussions and Meet the Professor Luncheons. We hope you will enjoy attending this newly structured scientific meeting.

CONFERENCES OBJECTIVES• Diagnose and treat the most frequent conditions by identifying recent

discoveries in basic, translational and clinical research in selected areas of pediatric nephrology, and assessing its impact in research development.

• Recognize and assess routine handling, processing and reporting of kidney biopsies with a systematic approach in the diagnosis of medical renal diseases.

• Assess and utilize genetic diagnostic testing in the practitioner approach to children with inherited pediatric nephrology disorders.

• Recognize the pathogenesis, diagnose complications and select appropriate management of children with nephrotic syndrome.

• Use recombinant growth hormone therapy in the management of children with growth impairment associated with chronic kidney disease (CKD) and assessment of nutrition abnormalities in children with this condition.

• More effectively manage children with CKD, dialysis and transplant and its complications.

• Evaluate pathogenesis, complications and management of infants and children with glomerular disorders and chronic kidney diseases.

• Assess the process of how to apply for research funds and recognize the importance of defining milestones and development of a curriculum for research for fellows in training.

• Establish appropriate diagnosis and management of children with various medical renal diseases by assessing the histopathologic findings obtained from kidney biopsies.

• Review practical protocols for the management of patients with extracorporeal therapies in the critical care setting.

Upon completion of the Seminar, participants should be able to define the various etiologies and physiologic conditions relating to these subjects, select appropriate diagnostic procedures, understand that which may occur

as a result of the disease process or treatment, and indicate appropriate therapy. In addition, those able to do basic or clinical research focused on pediatric nephrology challenges, will be stimulated by those knowledgeable about research issues and be informed about support sources. It is anticipated that the exchanges of knowledge occurring during this meeting, will help identify future research directions and new approaches and technologies that will eventually lead to a better understanding of these conditions and improved treatment and prevention strategies. It is expected that the Faculty will serve as role models for future generations of Pediatric Nephrologists and serve to stimulate interest in this field as a career choice. The Pediatric Nephrology Seminars have successfully addressed for over 43 years the issues of selecting the best faculty speakers, formal lectures of short duration followed by panel discussions and case-based presentations. Informal exchanges throughout the meeting allows for clear improvement in the professional gaps of the intended audience. The faculty, format and educational design will allow learners to give better patient care with regards to early detection of kidney disease in children or its complications (i.e growth hormone deficiency) and a more evidence based management of these conditions.

ACTIVITY LEARNING OBJECTIVESGoals for the Scientific Conference/Seminar.The purpose of the Pediatric Nephrology Seminar XLIV and the Renal Pathology Course will be to review the current state/knowledge of selected relevant areas of research in Pediatric Nephrology with clinical practice implications. The specific aims of the proposed scientific Seminar are:

1. To review the current understanding of the diagnosis and management of various kidney disorders with a focus on clinical research, clinico-pathologic correlations, current issues for the primary care practitioner, effects of nutrition, and recombinant growth hormone in chronic kidney disease, in-depth review on the nephrotic syndrome and selected glomerulopathies, on-going challenges in critical care nephrology, chronic kidney disease, dialysis and transplantation, and new developments in congenital obstructive uropathies and urolithiasis.

2. To identify the most critical and promising areas for future basic and clinical research efforts regarding Pediatric Nephrology.

3. To stimulate interest in Pediatric Nephrology as a career choice .

4. To provide role models for the next generation of Pediatric Nephrologists and a communication network for future collaboration and career support for retention of current trainees.

FACULTY DISCLOSURE AND CONFLICT OF INTEREST RESOLUTIONAll conflicts of interest of any individual(s) in a position to control the content of this CME activity will be identified and resolved prior to this educational activity being provided. Disclosure about provider and faculty relationships, or the lack thereof, will be provided to learners.

Pediatric Nephrology Seminar XLIV and the Renal Pathology Course are an international forum for pediatric and adult nephrologists, pediatricians, internists, general practitioners, renal pathologists, neonatologists, pediatric urologists, transplant surgeons, nurses, nutritionists and allied health professionals to review selected relevant subjects and share new scientific materials.

ACCREDITATIONThe University of Miami Leonard M. Miller School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATIONThe University of Miami Leonard M. Miller School of Medicine designates this live activity for a maximum of 27.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. This seminar has been planned and implemented in accordance with the essential areas and policies of the Florida Board of Nursing for Continuing Education Provider #50-2105. The University of Miami School of Nursing and Health Studies designates this live activity for a maximum of 26.50 CEU credits.

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ACKNOWLEDGEMENTSENDORSEMENTS

Carolyn L. Abitbol, M.D.Professor of Pediatrics Division of Pediatric Nephrology, Medical Director, Pediatric Dialysis Unit, Fellowship Training Program Director, Co-Director Pediatric Nephrology Seminar

Laura Barisoni, M.D.Professor of Pathology, Division Chief, Renal Pathology Service, Department of Pathology, Director Renal Pathology Course

Jayanthi Chandar, M.D.Associate Professor of Clinical Pediatrics, Division of Pediatric Nephrology, Medical Director Pediatric Kidney Transplant Program

Sheila Coakley, R.N.Pediatric Dialysis Unit, Nicklaus Children’s Hospital

Gabriel Contreras, M.D.Professor of Medicine, Division of Nephrology and Hypertension

Carlos Cuervo, M.D.Voluntary Assistant Professor of Pediatrics, Division of Pediatric Nephrology

Marissa Defreitas, M.D.Assistant Professor of Clinical Pediatrics, Division of Pediatric Nephrology

Christian Faul, Ph.D.Associate Professor of Medicine and Cell Biology, Division of Nephrology and Hypertension.

Michael Freundlich, M.D.Professor of Clinical Pediatrics, Division of Pediatric Nephrology Co-Director Pediatric Nephrology Seminar

Alessia Fornoni, M.D.Peggy and Harold Katz Family Professor of MedicineChief, Katz Family Division of Nephrology and HypertensionDirector, Peggy and Harold Katz Drug Discovery Center

Beverly Jackson, R.N.Pediatric Dialysis Unit, Holtz Children’s Hospital

Chryso Katsoufis, M.D.Assistant Professor of Clinical Pediatrics, Division of Pediatric Nephrology

Evel Michel, DNP, ARNPNurse Manager, Pediatric Dialysis Unit, Holtz Children’s Hospital

Michael A. Nares, M.D.Associate Professor of Clinical Pediatrics, Division of Pediatric Critical Care Medicine, University of Miami

José Strauss, M.D.Emeritus Professor, Division of Pediatric Nephrology, Former Chairman Pediatric Nephrology Seminars

David B. Thomas, M.D.Professor of Pathology, Department of Pathology, Co-Director Renal Pathology Course

Wacharee Seeherunvong, M.D.Associate Professor of Clinical Pediatrics, Division of Pediatric Nephrology

Marie Saintvil, R.N.Pediatric Dialysis Unit, Nicklaus Children’s Hospital

Kelli Walker, ARNP, MSNTherapy Development Specialist Gambro

Marcia Young, R.N.Pediatric Dialysis Unit, Holtz Children’s Hospital

Gastón E. Zilleruelo, M.D.Professor of Pediatrics, Director, Division of Pediatric Nephrology, Program Director, Pediatric Nephrology Seminar

Carmen Avila-Casado, M.D., Ph.D.Professor University of Toronto, Director of Education EM Lab, Secretary of the Renal Pathology Society Toronto, Ontario

Melvin Bonilla-Felix, M.D.Professor and Chair, Department of Pediatrics, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico

Patrick Brophy, M.D., Ph.D.Director of Pediatric Nephrology, Children’s Hospital, Iowa City, IA

Pierre Cochat, M.D., Ph.D.Responsable du Pôle des Spécialités Pédiatriques, Service de Néphrologie Rhumatologie Dermatologie, Centre de Référence des Maladies Rares ‘Néphrogones’ Hôpital Femme Mère Enfant & Université Claude-Bernard, Secretary General, International Pediatric Nephrology Association, IPNA, Lyon, Bron Cedex, France

Michelle R. Denburg, M.D.Assistant Professor of Pediatrics and Epidemiology, Division of Nephrology, The Children’s Hospital of Pennsylvania, Perelman School of Medicine at the University of Pennsylvania

Robert Ettenger, M.D.Distinguished Research Professor, Emeritus, Department of Pediatrics, Division of Nephrology, Mattel Children’s Hospital, UCLA, David Geffen School of Medicine at UCLA

Maria Ferris, M.D., Ph.D., MPHAssociate Professor and Director, Pediatric ESKD and Transition Programs, University of North Carolina Kidney Center, UNC at Chapel Hill, NC

Guido Filler, M.D., Ph.D.Professor of Pediatrics, Department of Pediatrics, Children’s Hospital, London Health Science Centre University of Western Ontario, Canada

Richard N. Fine, M.D.Professor of Pediatrics, State University of NY at Stony Brook, NY

Joseph T. Flynn, M.D.Dr. Robert O. Hickman Endowed Chair in Pediatric Nephrology, Professor of Pediatrics, University of Washington, Chief, Division of Nephrology, Seattle Children’s Hospital, Seattle, WA

Rasheed A. Gbadegesin, MBBS, M.D.Associate Professor of Pediatrics, Division of NephrologyDuke University Medical Center, Durham, NC

William F. Glass II, M.D., Ph.D., MBAProfessor and Vice Chair for Graduate Medical Education, Director of the Pathology Residency Program, Director of Renal Pathology Services, UT Health /McGovern Medical School, Houston, TX

Ariel Gomez, M.D.Harrison Distinguished Professor of Pediatrics, Director, Child Health Research Center, Charlottesville, VA

Larry Greenbaum, M.D., Ph.D.Professor of Pediatrics and Chief Pediatric Nephrology, Emory University, Atlanta. President American Society of Pediatric Nephrology (ASPN)

Friedhelm Hildebrandt, M.D.Chief Division of Nephrology, Boston Children’s Hospital, Professor of Pediatrics, Harvard Medical School, Boston, MA

Frederick J. Kaskel, M.D., Ph.D.Professor and Vice Chair of Pediatrics, Director for Child Health Einstein/Montefiore Institute for Clinical and Translational Research, NY

Vera Koch, M.D.Professor of Pediatric Nephrology, Instituto da Crianza do Hospital das Clinicas, Universidad of Sao Paulo, School of Medicine, Brazil. Secretary General ALANEPE

John D. Mahan, M.D.Professor, Department of Pediatrics, Program Director, Pediatric Residency Program, Program Director, Pediatric Nephrology Fellowship Program, Vice Chair for Education, The Ohio State University COM, Columbus, OH

Chris McIntyre, M.D.Professor of Medicine, Medical Biophysics and Pediatrics, Robert Lindsay Chair of Dialysis Research and Innovation, Schulich School of Medicine and Dentistry, University of Western Ontario, Ontario, Canada

Mark Mitsnefes, M.D., M.S.Professor of Pediatrics, Division of Nephrology and Hypertension, Program Director Clinical Translational Research Center, Cincinnati Children’s Hospital, OH

Marva Moxey-Mims, M.D.Director Pediatric Nephrology and Renal Centers Programs NIH, NIDDK, DKUH, Bethesda, MD

Isidro Salusky, M.D.Professor of Pediatrics; Director, General Clinical Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA

Matthew G. Sampson, M.D.Assistant Professor of Pediatrics, University of Michigan, Ann Arbor, MI

William E. Smoyer, M.D.Director Center for Clinical and Translational Research, The Research Institute at Nationwide Children’s Hospital, Columbus, OH

H. William Schnaper, M.D.Professor of Pediatrics; Vice Chairman, Children’s Memorial Medical Center, Feinberg School of Medicine, Northwestern University, Chicago, IL; Past President , ASPN

Surya Seshan, M.D.Professor of Pathology, Department of Pathology, The New York Hospital-Cornell Medical Center, New York, NY; Renal Pathology Course Co-Director

Bradley Warady, M.D.Professor of Pediatrics, University of Missouri-Kansas City School of Medicine, Director Division of Pediatric Nephrology; Director of Dialysis and Transplantation, Children’s Mercy Hospital and Clinics, Kansas City, MO

Joshua Zaritsky, M.D.Chief of Pediatric Nephrology, Nemours/AI duPont Hospital for Children, Wilmington, DE

American Society of Pediatric Nephrology

Genentech

IPNA (International Pediatric Nephrology Association)

Mallinckrodt Pharmaceuticals

Retrophin

THURSDAY MARCH 2, 2017PRE-SEMINAR RENAL PATHOLOGY COURSEDIRECTOR: Laura Barisoni, M.D. CO-DIRECTORS: David B. Thomas M.D., and Surya Seshan M.D.

7:00-8:00 A.M. REGISTRATION. Continental Breakfast.8:00-8:10 A.M. INTRODUCTION. Opening Remarks. Gastón E. Zilleruelo, Laura Barisoni, M.D.

SESSION 1: PROTEINURIC LESSIONSModerator: Carmen Avila-Casado M.D., Ph.D.8:10-8:50 A.M. Processing and Reporting of Renal Biopsies David B. Thomas, M.D. 8:50-9:30 A.M. Algorithmic Approach to Renal Diseases Laura Barisoni, M.D. 9:30-10:10 A.M. New Classification of Podocytopathies (MCD-FSGS) Laura Barisoni, M.D. 10:10-10:30 A.M. BREAK10:30-11:10 A.M. Congenital and Infantile Nephrotic Syndrome William F. Glass II M.D., Ph.D.,MBA11:10-11:30 A.M. IgM-C1Q Nephropathies - David B. Thomas, M.D.11:30-12:00 P.M. Membranous GN - Laura Barisoni, M.D. 12:00-12:15 P.M. Discussion12:15-1:15 P.M. LUNCH

SESSION 2: HEMATURIAS/NEPHROTIC SYNDROMESModerator: William F. Glass II M.D., Ph.D., MBA

1:15-2:00 P.M. MPGN/DDD/C3 Nephropathy Carmen Avila-Casado, M.D., Ph.D.2:00-2:40 P.M. IGA-HSP - Surya Seshan, M.D.2:40-3:10 P.M. Post-Infectious GN Carmen Avila-Casado, M.D., Ph.D.3:10-3:30 P.M. BREAK

SESSION 3: SYSTEMIC DISEASES Moderator: David B. Thomas M.D.

3:30-4:15 P.M. Lupus Nephritis - Surya Seshan, M.D.4:15-4:45 P.M. Vasculitis - David B. Thomas, M.D.4:45-5:15 P.M. Thrombotic Microangiopathy - Surya Seshan, M.D.5:15-5:30 P.M. Discussion

FRIDAY, MARCH 3, 20177:00-8:00 A.M. REGISTRATION. Continental Breakfast.

SESSION 4: TRANSPLANT PATHOLOGY & CLINICAL CHALLENGESModerators: Surya Seshan, M.D., Jayanthi Chandar, M.D.8:00-8:20 A.M. Allograft Rejection: Cellular, AMR Carmen Avila-Casado, M.D., Ph.D. 8:20-8:40 A.M. Recurrent and De-Novo Glomerular Diseases Surya Seshan, M.D. 8:40-9:00 A.M. Transplant Infections William F. Glass II, M.D., Ph.D., MBA 9:00-9:20 A.M. Immunomonitoring Post Tx: is it useful? Jayanthi Chandar, M.D. 9:20-9:40 A.M. Newer Approaches for Immunosuppression 2017 Robert Ettenger, M.D. 9:40-10:00 A.M. Steroid Free Protocols in Pediatric Transplantation Richard Fine, M.D.

10:00-10:30 A.M. Panel Discussion10:30-11:00 A.M. BREAK/Visit Exhibitors

SESSION 5: CLINICO-PATHOLOGIC CORRELATIONSModerators: David B. Thomas, M.D., Wacharee Seeherunvong, M.D.11:00-1:00 P.M. Case Presentations and Discussion1:00-2:00 P.M. Lunch. Meet the Professors Luncheon

SESSION 6: NEONATAL NEPHROLOGY Moderators: Joseph T. Flynn, M.D., Carolyn L. Abitbol, M.D.2:00-2:20 P.M. Neonatal AKI & Developmental Biomarkers in Preterm infants Patrick Brophy, M.D. 2:20-2:40 P.M. Neonatal Kidney Volume: Should we Measure it? Carolyn L. Abitbol, M.D.2:40-3:00 P.M. Neonatal Hypertension: Management and Complications - Joseph T. Flynn, M.D.3:00-3:20 P.M. Cardiorenal Syndrome After Preterm Birth Carolyn L. Abitbol, M.D. 3:20-3:40 P.M. Panel Discussion3:40-4:00 P.M. BREAK

SESSION 7: GENETICS FOR THE CLINICIANModerators: Vera Koch, M.D., Friedhelm Hildebrandt, M.D., Ph.D. 4:00-4:20 P.M. Genetic Algorithm Screening in Nephrotic Syndrome Friedhelm Hildebrandt, M.D.,Ph.D. 4:20-4:40 P.M. Role of Genetics in VUR Rasheed A. Gbadegesin, M.D.4:40-5:00 P.M. Genetic Forms of Urolithiasis Friedhelm Hildebrandt, M.D., Ph.D.5:00-5:20 P.M. What Have We Learned from the NEPTUNE Study? - Matthew G. Sampson, M.D. 5:20-5:40 P.M. Fabry nephropathy: Early Screening, Diagnosis and Management - Pierre Cochat, M.D. 5:40-6:00 P.M. Panel Discussion 6:00-6:30 P.M. Special Lecture: Developmental Nephrology: State of the Art Ariel Gomez, M.D. 6:30-7:30 P.M. WELCOME RECEPTION

SATURDAY MARCH 4, 20177:30-8:00 A.M. REGISTRATION. Continental Breakfast.

SESSION 8: INNOVATIVE CONCEPTS & THERAPIES IN GLOMERULAR DISORDERSModerators: Alessia Fornoni M.D., William E. Smoyer, M.D. 8:00-8:20 A.M. Role of the Interstitium and Salt in the Progression of CKD H. William Schnaper, M.D.8:20-8:40 A.M. Role of Lipids in the Progression of CKD Guido Filler, M.D., Ph.D.8:40-9:00 A.M. Atypical HUS: New Concepts for Dx and Management Larry Greenbaum, M.D., Ph.D.9:00-9:20 A.M. Gluten Free Diets in the Nephrotic Child Frederick J. Kaskel, M.D., Ph.D.

Program PEDIATRIC NEPHROLOGY SEMINAR 2017

Program PEDIATRIC NEPHROLOGY SEMINAR 20179:20-9:40 A.M. Evidence Based Strategies for Management of Steroid Resistant/Dependent NS William E. Smoyer, M.D.9:40-10:00 A.M. Lupus Nephritis: Management Update 2017 Gabriel Contreras, M.D.10:00-10:30 A.M. Panel Discussion10:30-11:00 A.M. BREAK and Visit Exhibitors11:00-11:10 A.M. The José Strauss Visiting Professor Award

SESSION 9: CARDIOVASCULAR-KIDNEY INTERACTIONS IN CKDModerators: Guido Filler, M.D., Ph.D., Melvin Bonilla-Felix, M.D.

11:10-11:30 A.M. Dysregulated Vit D Metabolism in Proteinuric Nephropathies Michelle R. Denburg, M.D. 11:30-11:50 A.M. FGF23 is it Cardiotoxic? - Christian Faul, Ph.D. 11:50-12:10 P.M. Vitamin D is it Cardioprotective? Michael Freundlich, M.D.12:10-12:30 P.M. Update on Vascular Calcifications in CKD Isidro Salusky, M.D.12:30-12:50 P.M. Cardiorenal Syndrome Type 4 Guido Filler, M.D., Ph.D.12:50-1:10 P.M. Panel Discussion1:10-2:10 P.M. Meet the Professors Luncheon

SESSION 10: WORKSHOP ON GROWTH & NUTRITION IN CKDModerators: Carolyn L. Abitbol, M.D., Richard Fine, M.D. 2:10-2:30 P.M. Optimizing Growth in Children with CKD John Mahan, M.D.2:30-2:50 P.M. ABC of Nutritional Management of Children with CKD -Bradley Warady, M.D.2:50-3:10 P.M. Role of rHu-GH in CKD and Post Renal Transplantation Richard Fine, M.D.3:10-3:30 P.M. Assessment of Vascular Stiffness and the Role of Statins in Children with CKD Mark Mistnefes, M.D.3:30-3:50 P.M. Nutritional Support in Critically Ill Children with AKI Carolyn L Abitbol, M.D.3:50-4:10 P.M. BREAK4:10-5:10 P.M. Case Studies and Discussion5:10-6:00 P.M. Medical Knowledge Competency Assessment

SUNDAY, MARCH 5, 20177:00-8:00 A.M. REGISTRATION. Continental Breakfast.

SESSION 11: RESEARCH AND TRAINING INITIATIVESModerators: Maria Ferris, M.D., Ph.D., MPH, John Mahan, M.D.8:00-8:20 A.M. Education for Global Fellows in Research (eGFR) Curriculum - Maria Ferris, M.D., Ph.D., MPH 8:20-8:40 A.M. Grant Writing: Tips for a Successful Application Marva Moxey-Mims, M.D.8:40-9:00 A.M. IPNA Training Centers Initiative Pierre Cochat, M.D., Ph.D.

SESSION 12: DIALYSIS AND CRITICAL CARE NEPHROLOGYModerators: Bradley Warady, M.D., Chryso Katsoufis, M.D. 9:00-9:20 A.M. Renal Replacement Therapy in Critically Ill Children Patrick Brophy, M.D.

9:20-9:40 A.M. The Neonate with ESRD: Management and Outcomes Bradley Warady, M.D.9:40-10:00 A.M. The Dark Side of Dialysis Christopher McIntyre, M.D.10:00-10:20 A.M. BREAK/Visit Exhibitors 10:20-10:40 A.M. Iron Metabolism and Therapy in CKD Joshua Zaritsky, M.D.10:40-11:00 A.M. Challenges in the Transition of ESRD Care Maria Ferris, M.D., Ph.D. MPH11:00-11:30 A.M. Panel Discussion Alexander Hotel Sessions Conclude

WORKSHOP ON PEDIATRIC CRITICAL CARE NEPHROLOGY (To be conducted at Holtz Children’s Hospital/ University of Miami)Coordinator: Carolyn L. Abitbol M.D.

1:00-1:10 P.M. Introduction Carolyn L. Abitbol, M.D 1:10-1:30 P.M. Developing a Program: Challenges & Rewards Evel Michel, DNP, ARNP1:30-2:00 P.M. AKI: Modalities with Versatility Patrick Brophy, M.D.2:00-2:30 P.M. Vascular Access for acute dialytic modalities Michael Nares, M.D.2:30-4:30 P.M. Workshop Stations Wacharee Seeherunvong, M.D. Chryso Katsoufis, M.D. Marissa DeFreitas, M.D. Sheila Coakley, R.N. Marie Saintvil,R.N. Marcia Young, R.N. Beverly Jackson, R.N. Kelli Walker, MSN, ARNP4:30-5:00 P.M. Final Assessment & Certificates Carolyn L. Abitbol, M.D. Jayanthi Chandar, M.D. Carlos Cuervo, M.D.

ADJOURN

Flanked by the roaring Atlantic Ocean and rippling Intracoastal Waterway, the Alexander All Suite Ocean Front Resort is located in the heart of

Miami Beach. Attendees will enjoy late-winter in South Florida which is unlike that in any other part of the U.S. thanks to a subtropical climate and

strong Caribbean/Latin American influences. It’s just the right place for recharging your personal and professional perspectives in the company of

friends and colleagues. You won’t need your coat, boots, or umbrella, but a light jacket may feel good in Miami’s moonlit evening breezes and super-air

conditioned restaurants.

Room Rates: US $310.00 + US $15.00 Resort Fee and 13% tax-Single/Double Occupancy- European plan

(meals not included).

Room rates apply three day prior to, during and three days after the Seminar. Reservations must be received by February 6, 2017 to take advantage of

the above rate. Please use attendee code 38X5X4 when making your reservations for a discounted rate.

After this date, reservation requests will be considered on a space available basis.

Advanced Registration Fee:Renal Pathology Course ONLY US $125.00Pediatric Nephrology Seminar ONLY US $375.00Pediatric Renal Pathology Course and Pediatric Nephrology Seminar US $475.00CRRT Workshop on Sunday afternoon ONLY US $ 50.00Physicians in Training (except Grantees), Nurses and Allied Health Professionals* US $295.00

* Physicians in Training will need letter of verification from Chief of service. Tuition includes admission to scientific sessions, a course flash drive and continental breakfasts. After February 20, 2017 and (On-Site) US $550.00 for physician in practice and US $330.00 for others.

PLEASE NOTE THAT ONLY US CHECKS AND MONEY ORDERS CAN BE ACCEPTED FOR ONSITE REGISTRATION. NO CREDIT CARDS CAN BE ACCEPTED ON SITE.

Services for the Disabled:If special arrangements are required for an individual with a disability to attend this conference, please contact: Yvette Arauz, (305) 585-6726 and the Alexander All Suite Ocean Front Resort 1-800-327-6121 or (305) 865-6500 no later than February 20, 2017.

For Additional Information, contact:Department of PediatricsDivision of Pediatric NephrologyP.O. Box 016960 (M-714)Miami, FL 33101Tel. (305) 585-6726Email: pediatricnephrology@med.miami.edu

To register online, visit http://pediatrics.med.miami.edu/nephrology/seminar select conference you are attending and click register and pay.

Registration Cancellation PolicyRefunds will be made only if written notice of cancellation is received prior to February 20, 2017. A US $75.00 fee is charged to all refunds. After this date, no refunds will be made. In cases where a course is cancelled due to insufficient registrations, a full tuition refund will be made.

Hotel InformatIon

The Alexander ALL SUITE OCEANFRONT RESORT

5225 Collins Avenue, Miami Beach, FL 33140Tel: 1-800-327-6121 or (305) 865-6500

Email: reservations@alexanderhotel.com

PEDIATRIC NEPHROLOGY SEMINAR XLIVRegistration Information