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§ Cybercitizen Health EU – 2012 – Cancer

§ Cybercitizen Health US – 2011 Cancer 2012 ADD ADHD 2012 HIV/AIDS 2012 MS

§ ePharma Consumer US – 2011 Epilepsy Segmentation

§ Cybercitizen Health US – 2013 Reference Deck

§ ePharma Consumer US – 2012 Manhattan Research consumer study

Manhattan Research

Consumer HCP

§ ePharma Physician US 2011 – Urologists § Taking the Pulse US – 2010 Allergists

2010 Neurologists § Taking the Pulse – 2012 Pharmacists § Taking the Pulse – 2013

Cardiologists Endocrinologists Neurologists Oncologists PCPs Psychiatrists Rheumatologists

§ ePharma Physician US – 2012 § Taking the Pulse 2011 – Europe § Taking the Pulse 2012 - BRIC § Taking the Pulse 2013 - US

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Manhattan Research: Taking the Pulse Global

Country-specific HCP technology/social usage, resources, pharma company relationships

Taking the Pulse § Australia 2014 § Brazil 2014 § Canada 2014 § China 2014 § Europe 2013

§ France § Germany § Italy § Spain § UK

§ India 2014 § Japan 2014 § Mexico 2014 § Middle East 2013 § Russia 2014 § South Africa 2013 § Turkey 2014

Digital Workflow: How are physicians flowing across screens and platforms and how can marketers provide value-add

content and services ?

Media Mix: Which sources are physicians relying on day-to-day to conduct their practices?

Mobile optimization: How are smartphones and tablets

impacting decisions?

Pharma relationship: How can pharma leverage relationships with physicians both online and offline?

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Taking the Pulse® Global 2014 Study Methodology Summary

Source: Manhattan Research, Taking the Pulse® Global 2014

How was the survey conducted?

When was the survey fielded/released?

The 2014 survey was conducted online.

The survey was fielded in Q1 of 2014.

Where was the survey conducted?

In order to optimize the study and provide geographic diversity, various regions were targeted in each country. First, second, and third tier cities were targeted, as well as segments of non-urban physicians in each

country, including rural physicians from towns, villages, outer-suburbs, county-level cities, and the countryside. Of the physicians who participated in the survey, 50% live in Tier 1 cities, 35% live in Tier 2

cities, and 15% live in Tier 3 cities. 

Australia Brazil Canada China India Japan Mexico Russia Turkey

Total Participants

228 205 230 362 201 202 203 204 202

PCPs 121 99 111 151 100 100 100 101 101

Specialists 107 106 119 211 101 102 103 103 101

Surveyed face-to-

face/phone

- 103 - 157 100 - 101 90 102

Surveyed Online

228 102 230 205 101 202 102 114 100

Non-urban physicians

34 50 50 87 44 51 45 46 47

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Taking the Pulse® Global 2013 Study Methodology Summary

Source: Manhattan Research, Taking the Pulse® Global 2014

How was the survey conducted?

When was the survey fielded/released?

The Taking the Pulse Europe 2013 survey was conducted online and recruited via email. The Middle East and South Africa Taking the Pulse 2013 surveys were conducted via face to

face interviews.

The Europe survey was fielded and released in Q4 of 2013. The Middle East survey and the South Africa survey were both conducted December 2013 – February 2014.

Where was the survey conducted?

The 2013 survey was conducted online and physicians were recruited via email. Physicians were told it was regarding “communication channels” within their practice and were given the option to complete the survey

in the language of their choice (options were German, Spanish, French, Italian, or English).

Europe: France

Europe: Germany

Europe: Italy

Europe: Spain

Europe: UK

Middle East

South Africa

Total Participant

s

256 248 249 252 250 110 (50 United Arab

Emirates, 30 Kuwait, 30 Saudi Arabia)

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Today’s Focus

•  What’s New? •  What’s Unexpected and Surprising? •  How are HCPs different?

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Digital WorkFlow

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Digital  Workflow:  

Triple  screen  threat:  The  majority  of  all  2014  surveyed  na8ons’  HCPs  u8lize  their  desktop/laptop,  smartphone,  and  tablet  in  their  workday.    

•  Japan  is  the  only  excep8on,  where  less  than  half  of  their  physicians  (47%)  u8lize  triple  screens  for  professional  purposes.    

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Digital  Workflow:  

Top  Screen:  While  many  HCPs  use  desktop/laptop  the  most  as  their  top  screen  during  the  workday  and  during  pa8ent  consulta8ons,  some  HCPs  in  certain  markets  do  spend  the  most  8me  on  other  devices    

•  Notably,  physicians  in  China,  India,  Mexico,  and  Russia  spend  more  8me  on  their  smartphones  during  the  workday  than  on  their  desktop/laptop  or  tablet  device    

•  When  comparing  tablet  and  smartphone  professional  usage,  most  polled  countries  indicate  equal  usage,  with  a  few  excep8ons  

•  HCPs  in  Japan  are  more  likely  to  own  a  tablet  than  a  smartphone  

•  Physicians  in  Turkey  are  more  likely  to  use  their  smartphone  during  the  day  than  a  tablet  

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Device  Profile:  In  terms  of  frequency  of  use,  desktops/laptops  are  the  leading  screen.  These  sessions  last  longer  than  sessions  on  tablets  and  smartphones  

Digital  Workflow:  

•  HCPs  use  their  desktop/laptop  anywhere  from  4  8mes  a  day  to  25  8mes  a  day,  with  sessions  las8ng  15  minutes  to  24  minutes  EACH    

Sharing  Resources:  Physicians  vary  in  terms  of  their  openness  with  sharing  a  digital  resource  with  pa8ents  during  a  pa8ent  consulta8on  

•  In  countries  such  as  Brazil,  Canada,  and  South  Africa,  physicians  are  open  to  usually  showing  a  resource  to  a  pa8ent  during  a  consulta8on      

•  HCPs  in  Australia,  China,  India,  Japan,  Middle  East,  Russia,  and  Turkey  occasionally  or  never  show  a  digital  resource  to  their  pa8ent  

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Digital  Workflow:  

Typical  workday:  In  all  countries,  physicians  spend  the  majority  of  their  workday  seeing  pa8ents  (anywhere  from  4.7  hours  to  7.5  hours  a  day)  

•  In  countries  such  as  China  and  Turkey,  physicians  do  not  report  spending  8me  on  EHR  plaWorms  in  their  workday  

Low EHR usage

High EHR usage

Australia – 72%

Brazil – 62%

Canada – 60%

India – 33%

Japan – 60%

Mexico – 51%

Russia – 33%

Turkey – 0%

China – 0%

France– 70%

Italy 21%

Germany- 46%

Spain – 74%

UK – 59%

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Media Mix

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Media  Mix:  

Source  of  InformaMon:  In  all  polled  countries,  the  majority  of  HCPs  prefer  digital  format  over  print  as  their  first  choice  when  looking  for  informa8on  to  guide  their  clinical  decisions  

India – 60%

China – 62%

Japan – 66%

Russia & South

Africa – 71%

Turkey and

Middle East- 73%

Canada – 80%

Brazil – 81%

Mexico – 82%

Australia – 86%

% of HCPs who prefer digital resources

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Media  Mix:  

Pharma  website  visitaMon:    Pharma  website  weekly  visita8on  amongst  physicians  ranges  from  19%  to  82%  in  a  country.    Pharma  websites  are  defined  as  pharmaceu8cal  product  websites,  customer  service  websites,  corporate  websites  and  disease/condi8on  websites  

•  Of  all  polled  countries,  the  majority  physicians  in  Russia  (82%)  visit  any  pharma  website  weekly  or  more  o[en,  indica8ng  that  those  physicians  are  most  willing  or  open  to  pharma-­‐sponsored  sources  for  informa8on  and  digital  assets  

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Media  Mix:  

0% 10% 20% 30% 40% 50% 60% 70% 80% 90%

100% Utilization and Interest in HCP communities

Already Use Very Interested Somewhat Interested Not interested

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Media  Mix:  

Local  Networks  

Doctors.net.uk  Coliquio  Egora  Medscape  Physician  Connect  Medicitalia  

NIH  Medportal.Ru  Weibo  Orkut  Quora  Bebo  

Viadeo  Tuen8  Xing  

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Mobile Optimization

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Mobile  OpMmizaMon:  

Top  Smartphone/Tablet  

•  The  Top  Smartphone  is  iOS/Apple  in  Australia,  Brazil,  Canada,  EU,  Japan,  Turkey,  and  South  Africa  

•  Android  is  the  top  smartphone  in  China,  India,  Mexico,  Middle  East,  and  Russia  

•  Incidentally,  physicians  in  China,  India,  Mexico,  and  Russia  also  reported  that  they  spend  more  8me  on  their  smartphone  than  on  their  desktop/laptop  during  the  workday,  indica8ng  that  the  Android  plaWorm  may  be  more  conducive  to  longer  usage  sessions  than  the  iOS  plaWorm  for  HCPs  

•  Android  plaWorm  is  gaining  trac8on  in  the  EU  smartphone  market  

•  The  Top  Tablet  is  iOS/Apple  in  Australia,  Brazil,  Canada,  China,  Japan,  EU,  Mexico,  Middle  East,  Turkey,  and  South  Africa  

•  Android  is  the  top  tablet  in  both  India  and  Russia  

•  Physicians  in  India  and  Russia  are  also  more  likely  to  have  both  a  smartphone  and  tablet  on  the  Android  plaWorm    

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Mobile  OpMmizaMon:  Interest  in  InteracMng  with  Pharma  via  Smartphone  

•  HCPs  vary  in  their  interest  in  using  pharma  resources  on  their  smartphone.  The  most  common  interests  that  respondents  chose  were  product  websites,  condiMon  specific  websites,  or  an  app  provided  by  a  pharma  company.    

55%

79%

48%

81% 74% 75% 90% 86%

75% 63% 63%

0%

20%

40%

60%

80%

100% HCP interest in smartphone pharma resources

*EU  not  depicted  

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Relationship with Pharma

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Pharma  RelaMonship:  Sales  Rep  Access:  Sales  rep  penetraMon  in  HCP  offices  vary  by  country  

87% 92%

77% 70%

83% 83% 91% 93% 91%

83% 91%

76%

92% 90% 81%

75%

0

5

10

15

20

25

0% 10% 20% 30% 40% 50% 60% 70% 80% 90%

100% Rep Access

Mean number of times Saw a rep last 6 months

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Pharma  RelaMonship:  

Why  do  HCPs  feel  that  rep  visits  are  beneficial?  

•  Product  informaMon  is  the  number  one  reason  why  HCPs  find  rep  visits  to  be  beneficial  

•  Physicians  in  India,  Russia,  and  Turkey  find  value  in  printed  brochures/pa8ent  educa8onal  materials  –  these  are  also  the  three  countries  with  lowest  EHR  usage  

0

1

2

3

4

5

6

7

8

9

Product Information Answering Specific questions relating to

products

Drug Samples Clinical Trial Results Information about Medical conferences/meetings

Printed brochures and other printed patient ed

leave behinds

Top Benefits

Excluding Middle East and South Africa

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Pharma  RelaMonship:  Tablet  Reps  

Australia Brazil Canada China France

Germany India Italy Japan Mexico

Middle East Russia

South Africa Spain Turkey UK

Saw an iPad rep 84% 63% 78% 46% 54% 60% 31% 68% 71% 70% 76% 22% 71% 75% 71% 65% Agree tablets add value to the meeting 50% 50% 44% 71% 27% 18% 63% 7% 10% 71% 81% 63% 63% 9% 68% 5%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100% Tablet Rep Details

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Pharma  RelaMonship:  

Why  do  HCPs  not  uMlize  Pharma  websites?  

Almost  all  polled  countries  listed  “InformaMon  is  biased”  as  the  number  one  reason  why  physicians  do  not  use  pharma  websites    

However,  the  majority  of  HCPs  agree  that  they  would  use  pharma  websites  more  with  certain  improvements:  

•  Regularly  updated  content  •  Beder  quality  pharma  websites  •  Links  to  other  medical  resources  •  Easier  to  navigate  

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Country by Country

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•  Reason for not using pharma websites is because HCPs feel the information is

biased. 10% read professional email newsletters from pharma companies

•  Most HCPs find Rx information on their own, but 92% are interested in sharing pharma provided patient educational materials with their patients

•  About half of Australian HCPs show interest in using pharma resources on a

smartphone

•  They under-index in their social network usage

•  About half carry their smartphone with them all day, and 86% prefer digital resources for clinical information. However, they spend the most time on desktops/laptops

Trusts Pharma?

Mobile Friendly?

Australia

Social Savvy?

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•  Their pharma website visitation is strong (60%). They are also the most ikely to trust a pharma-sponsored website and would find value in pharma company interaction in an online physician community.

•  There is a high demand for content catered specifically to Brazil

•  Reps have a broad reach in Brazil. HCPs refer to them for drug samples

•  HCPs in Brazil are more likely to go on social networks (Facebook is a top choice)

•  They spend more time on EHR platforms in a given workday than physicians in other countries

•  81% agree that their first choice for clinical information is digital sources

Trusts Pharma?

Mobile Friendly?

Brazil

Social Savvy?

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•  Low pharma site visitation, and low social network utilization. They do not use pharma websites because they feel the information is biased

•  Physicians use their tablets/smartphones almost equally compared to their desktops. About half carry their smartphone all day

•  They primarily use their smartphone/tablet devices to read news articles and abstracts

Trusts Pharma?

Mobile Friendly?

Social Savvy?

Canada

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•  Heavy smartphone usage. Physicians report it is the top screen used throughout the workday, followed by desktop

•  There is an interest in Chinese-specific resources from pharma. Their top reason for not using pharma websites more is because they do not know which website will have the information that they need

•  56% use the Weibo social network for professional purposes. While the minority use physician-only communities, 85% are very receptive with pharma involvement. 81% are interested in using a pharma-sponsored mobile resource

•  46% physicians in China reported seeing a rep with an iPad (iPad detail), with the majority still using printed materials. However, the majority agree that tablets add value to a rep visit

China

Trusts Pharma?

Mobile Friendly?

Social Savvy?

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•  More  EU  physicians  own  a  smartphone  than  any  other  device  for  professional  use  

•  But  more  8me  is  spent  on  their  desktop,  and  physicians  do  not  u8lize  tablet  very  o[en  in  the  work  day  

•  59%  access  medical  resources  in  English,  and  61%  are  interested  in  resources  created  specifically  for  their  country  

•  Their  top  social  networks  are  Google+,  LinkedIn,  and  Facebook  

•  18%  are  currently  on  physician  only  networks  

•  85%  recalled  seeing  a  rep  in  person,  and  reps  are  more  o[en  u8lizing  print  materials  rather  than  an  ipad  detail  

Trusts Pharma?

Mobile Friendly?

Social Savvy?

European Union: France, Germany, Italy, Spain, UK

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•  HCPs in India over-index in their agreement that pharma-sponsored communications are credible (26%). However, their top reason for not using pharma website is because they feel the information is biased

•  Majority are interested in pharma involvement in physician-only communities

•  Physicians use their three devices (desktop, tablet, and smartphone) but smartphone is the top screen during a typical workday

•  EHR platforms are used sparingly in the workday, and adoption is low

•  60% prefer digital resources (under-index compared to other countries)

Trusts Pharma?

Mobile Friendly?

Social Savvy?

India

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•  The percentage of physicians who use a tablet during the workday over-

indexes compared to other countries

•  While their top screen used throughout the day is the desktop, their smartphone/tablet usage is equal. Only 17% agree that smartphone is a critical resource in their working day

•  89% utilize websites designed for HCP audience. Half use any pharma website

•  Physicians predominately use Facebook, followed by Google+, for professional social networking

•  25% are currently on physician-only communities, and the majority are receptive to pharma company interactions

Trusts Pharma?

Mobile Friendly?

Social Savvy?

Japan

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•  HCPs in Mexico, on average, over-index in their time spend on digital resources in a typical workday when compared with other markets (2.9 hours)

•  Smartphone is their top screen used during the workday, and their tablet sessions are longer than desktop sessions

•  A strong percentage (82%) prefer digital resources and half would like to see a pharma-sponsored mobile app

•  61% visit any pharma website, and 94% are interested in pharma interaction in an HCP-only community

•  They also believe that pharma sources are credible

Trusts Pharma?

Mobile Friendly?

Social Savvy?

Mexico

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•  A strong percentage of physicians use Facebook for professional purposes (78%)

•  69% carry their smartphone and use it constantly

•  99% access materials in English because they feel they have the most complete information available, but half would like to see more country-specific professional resources

•  66% would prefer a physician online community without other information like medical news

Trusts Pharma?

Mobile Friendly?

Social Savvy?

Middle East (United Emirates, Kuwait, Saudi Arabia)

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•  Smartphones are their top screen used throughout the day

•  82% of physicians visit any pharma website, over-indexing other countries

•  94% indicate they are open to pharma interaction in physician only networks, and 75% indicate an interest in pharma resources on their smartphone

•  Their top reason for not visiting pharma websites is because they do not know which websites have the information they need

Trusts Pharma?

Mobile Friendly?

Social Savvy?

Russia

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•  Percentage of physicians who use a smartphone is nearly equal to that of those who use a desktop, however, they still spend the most time on desktop devices in a typical workday

•  70% carry a smartphone and use it constantly. Of those who are interested in pharma resources on their smartphone, they would like to see condition-specific websites or product websites

•  High demand for specific patient education materials as well as materials created specifically for South Africa. 98% are interested in sharing patient educational materials provided from pharma companies

•  92% saw a rep and the majority agree that they trust and respect the professional opinion of their reps

Trusts Pharma?

Mobile Friendly?

Social Savvy?

South Africa

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•  Physicians in Turkey are moving towards mobile, however 22% carry a smartphone and use it constantly throughout the day

•  They do not use pharma communications because they feel information is biased or superficial, but 75% would be interested in pharma interaction in physician networks

•  64% are satisfied with the quality of medical digital resources in their local language

•  Pharma rep reach is not as broad as in other countries, but those who do see a rep have higher than average frequency

Trusts Pharma?

Mobile Friendly?

Social Savvy?

Turkey