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Management of Eye Injuries: Managing the Red or Injured Eye
Robert Baldor, MD, FAAFP
ACTIVITY DISCLAIMERThe material presented here is being made available by the American Academy of Family Physicians for educational purposes only. Please note that medical information is constantly changing; the information contained in this activity was accurate at the time of publication. This material is not intended to represent the only, nor necessarily best, methods or procedures appropriate for the medical situations discussed. Rather, it is intended to present an approach, view, statement, or opinion of the faculty, which may be helpful to others who face similar situations.
The AAFP disclaims any and all liability for injury or other damages resulting to any individual using this material and for all claims that might arise out of the use of the techniques demonstrated therein by such individuals, whether these claims shall be asserted by a physician or any other person. Physicians may care to check specific details such as drug doses and contraindications, etc., in standard sources prior to clinical application. This material might contain recommendations/guidelines developed by other organizations. Please note that although these guidelines might be included, this does not necessarily imply the endorsement by the AAFP.
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DISCLOSUREIt is the policy of the AAFP that all individuals in a position to control content disclose any relationships with commercial interests upon nomination/invitation of participation. Disclosure documents are reviewed for potential conflict of interest (COI), and if identified, conflicts are resolved prior to confirmation of participation. Only those participants who had no conflict of interest or who agreed to an identified resolution process prior to their participation were involved in this CME activity.
All individuals in a position to control content for this session have indicated they have no relevant financial relationships to disclose.
The content of my material/presentation in this CME activity will not include discussion of unapproved or investigational uses of products or devices.
Robert Baldor, MD, FAAFPProfessor and Vice Chair, Department of Family Medicine and Community Health/Director, Community-Based Education, Office of Undergraduate Medical Education/Director of Health Policy Education, Meyers Primary Care Institute/Medical Director, Center for Developmental Disabilities Evaluation and Research at the Eunice Kennedy Shriver Center, University of Massachusetts (UMass) Medical School, Worcester
Dr. Baldor has been teaching for 30 years and practices family medicine at the UMass Memorial Medical Center, Worcester. A member of the Massachusetts Governor’s Commission on Intellectual Disability, he has been recognized in The Best Doctors in America: Northeast Region and is a past-president of the Massachusetts Academy of Family Physicians. He publishes and presents regularly on a variety of family medicine topics and is an associate editor for The 5-Minute Clinical Consult. Dr. Baldor practices family medicine with a special interest in developmental and intellectual disabilities. Throughout the years, he has spoken on a variety of primary care topics at the AAFP's annual meeting.
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Learning Objectives1. Perform timely physical examinations to determine the nature
of an eye emergency and refer patients to an ophthalmologist as necessary.
2. Evaluate eye emergencies, particularly central retinal artery occlusion and intraocular foreign bodies, to determine when further testing or surgery might be necessary.
3. Coordinate with sub-specialists, to receive necessary care to prevent vision damage, for patients identified with symptoms of iritis.
Audience Engagement SystemStep 1 Step 2 Step 3
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An Approach..
Performing a timely physical exam to determine the involved anatomical element will assist with your diagnosis and treatment methods.
The Eye….
• Lids/lashes
• Lacrimal system
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The Anterior Segment….
• Conjunctiva– Sclera
• Cornea– Iris
– Lens
J marchn/Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=34828874
Conjunctiva• Sclera
CorneaAnterior Chamber
• Iris• Pupil• Lens
Posterior Segment• Vitreous• Optic Nerve• Macula
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The Posterior Segment….
Vitreous
• Retina
• Optic Nerve
• Macula
Red Flags…
HISTORY• Trauma
• Recent ocular surgery
• Contact lens use
SYMPTOMS• Severe pain
• Severe photophobia
• Nausea/vomiting
https://commons.wikimedia.org/wiki/File:Red_flag_II.svg
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Acuity…
• The most worrisome history is a report of a recent decline in visual acuity!!
Always check visual acuity on exam…
A TC A N D Y
Modified: commons.wikimedia.org/wiki/File:1606_Snellen_Chart-02.jpg
The Ophthalmologic exam…
• Conjunctiva– Blood vessels injected? (focal or diffuse)
• Global tenderness to palpation? – Sclera involved?
• Cornea involved?– Fluorescein staining
• Size, shape and reactivity of the pupils– Iris details
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Red Flags…
ORBITAL SIGNS…
• Severe tenderness of globe or eyelids
• Significant periorbital erythema
• Decreased ocular motility
• Proptosis
https://commons.wikimedia.org/wiki/File:Red_flag_II.svg
Periorbital cellulitis
SYMPTOMS/SIGNS • Periocular pain
• Periorbital swelling
• Normal vision
TREATMENT
Broad Spectrum PO Antibiotic
• Gram positive coverage
Cephalexin or cloxacillin
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Orbital cellulitis
SYMPTOMS/SIGNS • Periocular pain
• Decreased eye movement
• Periorbital swelling
• Proptosis
TREATMENT
IV antibiotics
• 2nd
Generation cephalosporin Cefuroxime
• Referral
https://aneskey.com/preseptal-and-orbital-cellulitis/
Dacryocystitis
SYMPTOMS/SIGNS
• Periocular pain
• Infero-nasal swelling
• Purulent material refluxed from punctum w/pressure on distended lacrimal sac
• Normal vision
TREATMENT
• Broad Spectrum Antibiotic
• Referral
Dr. Dorothy L. Hitchmoth, PLLC
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Blepharitis
SYMPTOMS/SIGNS
• Morning stickiness
• Burning/itchy
• Lid margin debris/erythema
• Normal vision
TREATMENT
• Baby shampoo to clean lids
• Topical antibiotic qhs to eyelid margins
Dr. Dorothy L. Hitchmoth, PLLC
Dry Eyes
SYMPTOMS/SIGNS
• Itchy/burning
• Worse as day goes on
• Decreased tear film
• Vision usually normal
TREATMENT
• Artificial tears
https://creativecommons.org
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` Red Flags: The Ophthalmologic exam…
• Abnormal pupil shape, reactivity
• Circum-corneal injection (“ciliary flush”)
• Corneal signs– Fluorescein staining?
– White spots?
– Poor view of anterior chamber/iris?
https://commons.wikimedia.org/wiki/File:Red_flag_II.svg
AES Question #1
Chemosis is most often seen with which one of the following conditions?
1. Allergic conjunctivitis
2. Bacterial conjunctivitis
3. Chemical conjunctivitis
4. Viral conjunctivitis
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Conjunctivitis (Allergic)
SYMPTOMS/SIGNS
• Itching
• Injected conjunctiva/ chemosis
• Lid erythema/inflammation
• Vision usually normal
TREATMENT• Topical antihistamines
– Ketotifen
• Topical mast cell stabilizers – Cromolyn
Dr. Dorothy L. Hitchmoth, PLLC
Conjunctivitis (Bacterial)
SYMPTOMS/SIGNS
• Constant red eye with purulent discharge
• Injected conjunctiva with discharge
• Vision usually normal
TREATMENT
• Topical antibiotics– Bacitracin/neomycin/polymyxin
– Erythromycin
– Sulfacetamide
Dr. Dorothy L. Hitchmoth, PLLC
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Infectious Keratitis (bacterial)
SYMPTOMS/SIGNS
• Severe pain
• White pus on cornea
• Blurry vision
• Decreased vision
TREATMENT
• Topical antibiotics– Cefazolin and tobramycin
• Referral
Conjunctivitis (Viral)
SYMPTOMS/SIGNS • Constant red irritated eye
• Watery discharge
• Small follicles on lower bulbar conjunctiva
• Vision usually normal
TREATMENT
• Reassurance
https://commons.wikimedia.org/wiki/File:Hemorragicconjunctivitis2.jpg
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Pinguecula & Pterygia
SYMPTOMS/SIGNS
• Elevated conjunctival thickening of inter-palpebral region
TREATMENT• Artificial tears
• Topical NSAIDs– Ketorolac,
diclofenac
https://commons.wikimedia.org/wiki/File:Pterygium.png
Episcleritis
SYMPTOMS/SIGNS
• Mild Eye achiness
• Focal/diffuse injection of sclera deep to the conjunctiva
• Vision normal
TREATMENT
Topical NSAIDs
• Ketorolac, diclofenac
https://commons.wikimedia.org/wiki/File:Scleritis.png
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Scleritis
SYMPTOMS/SIGNS
• Severe eye pain with radiating headache
• Diffuse bluish/purple hue to sclera
• Tender to palpation
• Vision maybe decreased
TREATMENT
• Systemic steroids
• Refer
Iritis (Uveitis)
SYMPTOMS/SIGNS
• Pain/Blurry vision
• Photophobia
• Small pupil/Perilimbal erythema
• WBCs in anterior chamber
• Decreased vision
TREATMENT• Refer
• Topical steroid hourly
• Topical dilator BID– Phenylephdrine
https://upload.wikimedia.org/wikipedia/commons/e/ec/Iritis
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Acute angle-closure glaucoma
• Risk factors: hyperopia, myopia, narrow angle, shallow anterior chamber
• An attack can occur as a result of dim lighting• Medication side effect:
– Dilating drops– Anticholinergics (e.g. antidepressants)– Sulfa & topiramate can cause ciliary body
swelling w/ secondary angle closure
https://upload.wikimedia.org/wikipedia/commons/1/13/Acute_Angle_Closure-glaucoma.jpg
Acute angle-closure glaucoma
SYMPTOMS/SIGNS
Blurred vision, frontal headache, colored halos around lights, pain, discomfort, nausea/vomiting
• Increased intraocular pressure (> 30 mmHg) o Globe firm to palpation
• Sluggish pupillary light reaction
• Shallow anterior chamber
• Corneal haziness, injected conjunctiva.
https://www.flickr.com/photos/communityeyehealth/5686392027
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Acute angle-closure glaucoma
APPROACH/TREATMENT
Lower the increased intra-ocular pressure• 1gtt 0.5% timolol, 1% apraclonidine & 2% pilocarpine
– 1 minute apart, along with 500-mg acetazolamide PO
– IOP should be measured & treated hourly
• Definitive treatment is laser iridotomy
Corneal abrasion
SYMPTOMS/SIGNS
Pain, tearing, photosensitivity
• Blepharospasm, foreign body sensation, or blurry vision.
• Minimal trauma (eye rubbing, contacts)– High-velocity injury - penetrating eye injury?
• Fluorescein staining
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Fluorescein staining
• A drop of topical anesthetic o Proparacaine 0.5%
• Touch strip onto conjunctiva
• Abrasion may stain yellow; cobalt blue light shows a green defect
• Multiple vertical lines suggest a foreign body under upper eyelido Evert eyelid to look for foreign body
https://commons.wikimedia.org/wiki/File:Human_cornea_with_abrasion_highlighted_by_fluorescein_staining.jpg
Dendritic Staining: Infectious Keratitis (HSV)
• Topical antiviral
– Trifluridine
• Topical steroid
• Referral
Dr. Dorothy L. Hitchmoth, PLLC
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AES Question #2
Corneal abrasions are best treated with which one of the following methods?
1. PO analgesics, antibiotic drops, patching x 24hrs
2. PO analgesics, antibiotic drops, patching until symptom-free
3. PO analgesics, antibiotic drops, no patching
4. PO analgesics only
Corneal Abrasion: Treatment goals….
Relieve pain, prevent infection, speed healing
• Oral analgesics
• Topical agents– Antibiotics (Erythromycin, Sulfacetamide)
– NSAIDs (Ketorolac, diclofenac)
– Cycloplegics (Cyclopentolate, Homatropine)
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Corneal foreign body
APPROACH/TREATMENT
Remove with saline irrigation or sweep with a cotton swab • If necessary use a 25-gauge needle • Foreign bodies may leave a rust ring
– Remove within a few days
Mechanical Globe Injury
Workplace, recreational events• Full-thickness rupture or laceration through
cornea/sclera • Blunt injury
o Thrown ball, MVA, physical attack• Laceration
o Knife, high-velocity projectile
pixabay.com/en/earth-globe-explosion-collapse-1773943/
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AES Question #3
The best test for mechanical globe disruption is which one of the following?
1. Retinal exam for ‘box-caring’
2. Litmus paper test
3. Seidel test
4. Tonometry
Mechanical Globe Injury
SYMPTOMS/SIGNS
• Eye pain, redness, tearing
• Decreased vision
• Irregular pupil or iris prolapse
• Dilution of fluorescein dye by aqueous flow o Positive Seidel test
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Mechanical Globe InjuryAPPROACH/TREATMENT
• Orbital CT for foreign bodies or fractures
• Superficial laceration (<1cm) w/no other findings o Topical antibiotics
• Avoid eye pressure, limit coughing or straining, antiemetics
• Prophylactic systemic fluoroquinolones
• Visible protruding foreign body should not be removedo Surgery w/in 24 hours
Chemical Injuries…
Acid or alkali exposure (liquid, powder, gas)• Alkali burns more common/more severe than acid
• Severity depends on pH and the duration of contact
• Place litmus paper in conjunctival fornix for pH
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Chemical Injuries…APPROACH/TREATMENT
• Topical anesthetics & 2 L lactated Ringer’s, NS or water irrigation
• Wipe upper & lower fornices w/swab to remove chemical crystals
• Check pH q5 minutes; irrigate until neutralized (pH 7.0 - 7.5).
• Immediate Referralo Topical ABX, artificial tears, steroids…
Central Retinal Artery Occlusion
Risk factors: Age > 70, atherosclerosis, diabetes, glaucoma, HTN, hyperlipidemia, migraine• Associated with giant cell arteritis (5-10%)
• Systemic disease: collagen vascular diseases, hypercoagulopathies, cardiac valvular disease, syphilis, sickle cell
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Central Retinal Artery Occlusion
SYMPTOMS/SIGNS
• Painless, sudden unilateral vision loss– May report amaurosis fugax
• Pupil may be dilated with sluggish reaction to light
• ‘Box-carring’ of blood within retinal vesselso Embolus may be seen
• Retinal pallor/cherry-red spot at fovea, retinal artery attenuation
Dr. Dorothy L. Hitchmoth, PLLC
Central Retinal Artery Occlusion
APPROACH/TREATMENT - Immediate Referral!
• Attempt to restore blood flow by lowering IOPo IV mannitol 0.25 to 2.0 g per kg once
o PO/IV acetazolamide(Diamox) 500 mg once
o Oral nitrates
o Lay patient flat on their back
• Ocular-digital massage to move embolus?
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Retinal Detachment
Annual incidence 12 in 100,000
Risk factors:– Age
– Ocular trauma
– Cataract surgery
– + FH
– Myopia (near sighted)
Dr. Dorothy L. Hitchmoth, PLLC
Retinal Detachment
SYMPTOMS/SIGNS
• Unilateral flashing lights
• Increase in floaters
• Vision may be unaffected or slightly cloudy
• Peripheral vision defect expands over a few days
TREATMENT
• Immediate referral
• Laser photocoagulation
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Practice Recommendations…
• Perform a thorough ophthalmologic exam & always include a test of visual acuity
• Keep an eye emergency reference handy
• Partner with a local eye care specialist with clear information on how to reach urgently
Topical Treatments…Antibiotics
• Erythromycin 0.5% ointment QID X 3days
• Polymyxin B/trimethoprim (Polytrim) solution, 1 drop, QID X 3days
• Sulfacetamide 10% (Bleph-10) solution 1 to 2 drops, QID X 3days
Antipseudomonal antibiotics• Ciprofloxacin 0.3% (Ciloxan) ointment; QID X 3days• Ciprofloxacin 0.3% (Ciloxan) solution; 1 to 2 drops, QID X 3days• Gentamicin 0.3% ointment TID X 3days• Gentamicin 0.3% solution; QID X 3days• Ofloxacin 0.3% (Ocuflox) solution; 1 to 2 drops, QID X 3days
Topical cycloplegics
• Cyclopentolate 1% (Cyclogyl) 1 drop, may repeat in five minutes if needed
• Homatropine 5% 1 drop, may repeat in five minutes if needed
Topical NSAIDs
• Diclofenac 0.1% (Voltaren) 1 drop, QID X 3days
• Ketorolac 0.4% (Acular LS) 1 drop, QID X 3days