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LOUISE PILOTE MD, MPH, PhD

CURRICULUM VITAE

Office Address: Division of General Internal Medicine,, McGill University Health Centre (MUHC) 687 Pine Avenue West, A4-23, Montreal, Quebec, Canada H3A 1A1 Telephone: Work: (514) 934-1934 ext. 44722 Home: (514) 486-6372 Fax:(514) 934-8293 Email: louise.pilote@mcgill.ca Date and Place of Birth: 04/19/61, Sherbrooke, Canada Marital Status: Married to Mark J. Eisenberg MD, MPH Children: Sarah Leah, Ariella, Elisheva, Elie, Eliana Languages: French/English EDUCATION Medical 1980-85 M.D.C.M., McGill University, Montréal, Québec, Canada Postgraduate Training Clinical 1985-88 Internal Medicine Residency, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada Research 1993-97 PhD in Epidemiology, University of California at Berkeley, Berkeley, California, USA 1994-95 Post-Doctoral Research Fellowship in Cardiology, The Cleveland Clinic Foundation, Ohio, Grants from the Heart and Stroke Foundation of Canada (accepted) and from Fonds de la recherche en santé du Québec (declined) 1992-94 Post-Doctoral Fellowship in Health Services Research, Stanford University; grants from the Heart and Stroke Foundation of Canada (accepted) and from Fonds de la recherche en santé

du Québec (declined) 1990-92 Robert Wood Johnson Clinical Scholars Program, Post-Doctoral Fellowship in Clinical

Epidemiology, Stanford University, Stanford, California, USA 1988-89 Master of Public Health, Harvard School of Public Health, Boston, Massachusetts, USA LICENSES AND CERTIFICATIONS 1991 State of California (license no. A049728) 1990 Corporation professionnelle des Médecins du Québec, (specialty in Internal Medicine) 1988 Fellow, Royal College of Physicians and Surgeons of Canada, Internal Medicine, FRCP(C) 1988 Diplomate, American Board of Internal Medicine 1986 Corporation Professionnelle des Médecins du Québec (license no. 86-649)

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ACADEMIC POSITIONS University 2007 Professor of Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada 2002 Associate Professor (with tenure), Department of Medicine, McGill University, Montreal, Quebec,

Canada 1995 Assistant Professor, Department of Medicine, McGill University, Montreal, Quebec, Canada 1998-present Associate Member, Department of Epidemiology and Biostatistics, McGill University, Montreal,

Quebec, Canada 1989-90 Assistant Professor, McGill University, Department of Epidemiology and Biostatistics, Addis Ababa, Ethiopia Hospital 2006-present Director, Division of General Internal Medicine, McGill University and McGill University Health

Centre, Montreal, Quebec, Canada 1995-present Staff Physician, Division of Internal Medicine, Montreal General Hospital 1995-present Medical Scientist, Division of Clinical Epidemiology, Montreal General Hospital 1991-94 Clinician at the General Internal Medicine Clinic at Stanford University, California 1991-94 Preceptor at University of California at San Francisco Clinic for the Homeless 1988-89 Part-time attending staff in Internal Medicine, McGill University teaching hospital, Queen Elizabeth Hospital CAREER AWARDS 2009-2013 Fonds de la recherche en santé du Québec/ chercheur nationaux 2008-2015 James McGill Professorship, McGill University 2007-2009 Fonds de la recherche en santé du Québec/ chercheur boursier-Senior (ranked first) ($83534) 2003-2008 William Dawson Scholar Chair, McGill University (equivalent to CRC, tier II) 2002-2007 Canadian Institutes of Health Research career award (ranked first) ($70,000/year) 2002-2006 Fonds de la recherche en santé du Québec/ chercheur boursier-clinicien junior 2 (ranked first)

(declined) 1997-2002 Research Scholarship Heart and Stroke Foundation of Canada (ranked first) ($53,000/year) 1997-2002 Medical Research Council of Canada career award (ranked first) (declined) 1997-2002 Fonds de Recherche en Santé du Québec/ chercheur boursier-clinicien (ranked first) (declined) HONORS 2008-2009 Lady Davis Fellowship Award for sabbatical, Hebrew University, Jerusalem, Israel 2008 Faculty Honour List for Educational Excellence, Faculty of Medicine, McGill University 2006 Staff Research Award, Department of Medicine (McGill University Health Centre) 1997 Canadian Society of Internal Medicine - Young Investigator Award ($2,500) 1997 MacDonald Award: Granted to the highest rated grant in the Heart and Stroke Foundation Research Scholarship Competition ($15,000 x 1 year) 1988-1989 Frank Knox Canada-Harvard Memorial Fellowship (Harvard University) 1988 Benjamin Levitan Cardiology Award (Royal Victoria Hospital) 1982 McGill Summer Project Scholarship 1981-1982 Greville-Smith Scholarship (McGill University) 1981 Faculty of Medicine Scholar (Dean's list, McGill University) 1980-1981 Greville-Smith Entrance Scholarship

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TEACHING 1. McGill Courses Undergraduate (medical students) 1997-present Attending Physician, Clerkship Ambulatory Care Teaching (160 hr/yr) 1995-2005 Tutor, Introduction to Clinical Medicine (ICM-A), McGill University (20 hr/yr) 1995-2005 Tutor, Introduction to Clinical Medicine (ICM-B), McGill University (30 hr/yr) 1995-2006 Tutor, McGill Epidemiology Course - 4th Year Medical Students, Small Group Teaching (8 hr/yr) Postgraduate Teaching (Residency) and Clinical Teaching 1999-present Examiner, Mock Oral Exams, 3rd Year Residents (6 hr/yr) 1999-2003 Organizer, Residents Research Day (6 hr/yr) 1996-2002 Examiner, Internal Medicine Oral Exam, Collège des médecins du Québec (16 hr/yr) 1995-present Attending Physician, Montreal General Hospital, Medical Wards (3 mo/yr) 1995-present Attending Physician, Montreal General Hospital, Internal Medicine Consultation Service (2 mo/yr) 1995-present Attending Physician, Emergency Room (8 hr/mo) 1995-2006 Research Coordinator, Internal Medicine Residency Program (20 hr/yr) Postgraduate Teaching (Research) 2006 Hypertension – The CHEP Guidelines 2005-2007 Seminar on Research Methods, Internal Medicine Residents, Montreal General Hospital 2002-present Yearly Student Research Methods Workshop, Canadian Cardiovascular Outcomes Research and the

GENESIS Teams, Montreal General Hospital 2000 Instructor, Course in Pharmaco-Economics, 3 credits, Economic Evaluation of Medical

Technologies (516-630A), Department of Experimental Medicine, McGill University (3 hr) 1998 Instructor, 2-Day Visiting Lecture, Health Care MBA Program, University of California, Irvine,

Montreal General Hospital and McGill School of Management on International Business. (1 hr) 1988-2000 Instructor, Summer Course in Pharmaco-Economics, 3 credits, Economic Evaluation of Medical

Technologies (516-630C), Department of Experimental Medicine, McGill University (3 hr) 1997-2007 Residency Research Coordinator, Internal Medicine Postgraduate Residency Program, Montreal

General Hospital CME Courses 2002 Workshop on Health Economic Issues of Myocardial infarction, McGill University 1996 McGill Drug Therapy Course, Evidence-based management of acute myocardial infarction 2. Research Trainees Supervised Thesis Supervisor 2006-present George Thanassoulis MSc Effect of drug policy on process of care and outcome FRSQ Masters degree bursary 2005-present Michel Vallée MSc Sex differences in the incidence of hypertension 2005-2007 Igor Karp Post-doc Gender and sex determinants of cardiovascular diseases

Department of Medicine, McGill University GENESIS Scholar Award

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2004-2007 Suzanne Morin MSc Anti-resorptive agents in the treatment of osteoporosis: Recurrent hip fracture rates and mortality.

CIHR Bone Scholar Grant Department of Medicine, McGill University 2002-2005 Zheng Zhou PhD Statins in secondary prevention among elderly patients after AMI: Evaluation of class effect and the benefit of early use NSERC PhD Award, FRSQ Fellowship, CCORT PhD Fellowship Heart & Stroke Foundation Fellowship (declined) Department of Epidemiology and Biostatistics, McGill University Doctoral Research Award: Fonds de Recherche en santé du Québec 2002-2003 Christine Beck PhD Administrative Data Feedback For Effective Cardiac Treatment (AFFECT): A Cluster Randomized Trial Department of Epidemiology and Biostatistics, McGill University 2002-2006 Marie Hudson Post-doc Anti-inflammatory drugs and heart disease. CIHR Post-doc Award Post-doc CCORT Fellowship Award (declined) Department of Medicine

McGill University 2000-2003 Vidal Essebag PhD Anti-arrhythmic agents and pacemaker use. FRSQ PhD Fellowship Award FRSQ Post-doc Fellowship Award Department of Epidemiology and Biostatistics, McGill University 2000-2002 Jean-Marc Boucher Diploma Effect of pre-hospitalization ASA use on outcomes after acute coronary syndrome. Department of Epidemiology and Biostatistics, McGill University 2000-2002 Eric Rodrigues MSc Distance and access to acute myocardial infarction care. Dean’s Honor List MUHC Research Award Department of Epidemiology and Biostatistics, McGill University 1999-2001 Christine Beck MSc Use of instrumental variables in the analysis of administrative databases. Dean’s Honor List CIHR Master’s Student Fellowship Award Department of Epidemiology and Biostatistics, McGill University Thesis Co-Supervisor 2005-present Raluca Ionesco-Ittu Prevalence of congenital heart disease Department of Epidemiology and Biostatistics McGill University

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1998-1999 Guilin Li MSc Re-analyses of Framingham data using time-dependent covariates. Department of Epidemiology and Biostatistics, McGill University Thesis Committee Member 2008-present Aihua Liu PhD Is the risk of lung cancer in relationship to cigarette smoking

different between females and males? Department of Epidemiology and Biostatistics McGill University 2004-2008 Marie-Pierre Sylvestre PhD Time-dependent methods and survival analysis CIHR Doctoral Award Department of Epidemiology and Biostatistics McGill University 2003-2005 Kris Filion MSc The use and effectiveness of perioperative cardiac medical therapy

among patients undergoing bypass surgery. FRSQ Scholarship Department of Epidemiology, Biostatistics, and Occupational Health, McGill University 2002-2005 Igor Karp PhD Multi-variable methods for assessing changes over time in health status with application in arthritis and cardiovascular epidemiology. CCORT PhD Fellowship Award CIHR PhD Fellowship Award Department of Epidemiology and Biostatistics McGill University 2004-2006 Thao Huynh MSc AMI-Quebec: Treatment and outcomes of acute myocardial

infarction in Quebec. Montreal General Hospital 175th Anniversary Scholarship and Hoffmann-La Roche Pharma. Division of Cardiology, Department of Medicine, McGill University 2001-2004 Mylene Kosseim PhD Ranking Hospitals According to Acute Myocardial Infarction Mortality: Do the Methods Matter? 2001-2003 Karen Okrainec MSc Medical therapy following coronary revascularization:

Results from the ADORE Trial and the ROSETTA-CABG Study. FRSQ-FCAR MSc Bourse de formation Department of Epidemiology and Biostatistics, McGill University 1999-2001 Arik Azoulay MSc Cost of treatment of acute myocardial infarction in Canada

and the United States (INCCUS) study. Department of Epidemiology and Biostatistics, McGill University

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Medical Residents Research 2006-2008 Shadi Athaki MD Acute coronary syndrome in young adults 2005-2006 Keyhan Golyar MD The effectiveness of beta-blockers and angiotensin-converting enzyme inhibitors in women with congestive heart failure. Endocrinology training program Fellow Faculty of Medicine,

Division of Endocrinology, McGill University 2005 Khaled Buresly MD Bleeding risk with anticoagulants. Cardiology Fellow Department of Medicine, McGill University 2000-2002 Abdul Halabi MD Acute myocardial infarction at sites with and without

catheterization laboratory. Cardiology Fellow Department of Medicine, McGill University 1999-2001 Graham Wong MD Prognosis of diabetic patients with acute myocardial infarction.

Cardiology Fellow Department of Medicine, McGill University 1998-2000 Michel Doucet MD Relationship between hospital volume of PTCA and outcome. Cardiology Fellow Department of Medicine, McGill University Undergraduate Students 2006- 2008 Virginie Demers Medical Student, McGill University CCORT Summer Student 2005-2006 Melanie D’Almeida Medical Student, McGill University 2005-2006 Robert Segal Undergraduate Student, McGill University 2002-2003 Gaëlle Camus Undergraduate Student, McGill University CCORT Summer Student 2002-2003 Patrick Merrett Undergraduate Student, McGill University Challenge Grant, Government of Canada 1999-2001 Ewurabena Simpson Quality of life after acute myocardial infarction. Undergraduate Student, McGill University Challenge Grant, Government of Canada McGill Winter Bursary

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3. Other Research-related Teaching 2002-2009 Organizer, GENESIS ICE team annual meeting 2002-2006 Organizer, Student Day GENESIS/CCORT 2005-2006 Organizer, GENESIS Workshop at the Canadian Cardiovascular Society, The Montreal General Hospital, October 24, 2005. 2005 Gene-environment CIHR funded interdisciplinary capacity enhancement teams,

Workshop at the Canadian Cardiovascular Society, October 25, 2005. 2002-2003 Organizer, Canadian Cardiovascular Outcomes Research Team (CCORT) Student Research

Methods Workshop, Division of Clinical Epidemiology, The Montreal General Hospital, November 22, 2002; July 11, 2003 1997-1998 Coordinator, Monthly Cardiovascular Epidemiology Seminars, Division of Clinical Epidemiology,

The Montreal General Hospital 1995-1997 Monthly Journal Club with Internal Medicine. Critical Review of Literature 4. Invited Lectures & Seminars Within McGill 2007 Epidemiology Seminars: Statistics and Cancer, Department of Epidemiology 2006 Epidemiology Seminars: Effectiveness of cardiac drugs in women, Department of Epidemiology 2005 Epidemiology Seminars, Royal Victoria Hospital. Clinical trials in women with CVD 2005 Medical Grand Rounds, Montreal General Hospital and Royal Victoria Hospital. GENESIS-Gender

and sex determinants of Cardiovascular Disease: From Bench to Beyond 2005 Cardiology Round, Statins; A class effect, Montreal General Hospital 2003 CCORT Student Research Day. Research methods for cardiovascular outcomes research. 2002 Division of Clinical Epidemiology Seminar, Royal Victoria Hospital. Population-based analysis

of the effectiveness of cardiac drug use in Quebec. 2002 Medical Grand Rounds, Montreal General Hospital. Population-based analysis of the effectiveness

of cardiac drug use in Quebec. 2002 Medical Grand Rounds, Royal Victoria Hospital. Population-based analysis of the effectiveness

of cardiac drug use in Quebec. 2001 McGill University Cardiology Rounds. Acute myocardial infarction care in Quebec: How do we

perform? 2001 McGill Epidemiology Seminar at Purvis Hall. Use of instrumental variables to assess acute myocardial

infarction in Québec. 2001 Medical Grand Rounds, Montreal General Hospital. Treatment and outcome for acute myocardial

infarction in Québec: How do we perform? 2000 Division of Clinical Epidemiology Scientific Sessions, Montreal General Hospital. Quality of life after

acute myocardial infarction: A prospective cohort study. 1999 Medicine Rounds, Montreal General Hospital. ABCs of clinical epidemiology and how to embark

on a research project. 1999 Epidemiology Seminars, Centre for Clinical Epidemiology and Community Studies, Jewish General

Hospital. Quality of life after acute myocardial infarction: A preliminary analysis of a prospective cohort study.

1999 Cardiology Rounds, Montreal General Hospital, Quality of life after acute myocardial infarction: A preliminary analysis of a prospective cohort study.

1998 Cardiac Surgery Rounds, Montreal General Hospital. Availability of cardiac databases. 1998 McGill Epidemiology Seminar at Purvis Hall. Procedures and outcomes in the treatment of acute

myocardial infarction in Quebec and the United States 1998 Epidemiology Seminar at The Royal Victoria Hospital. Iron metabolism and coronary artery disease 1998 Interdivisional Internal Medicine Rounds. Pitfalls of practice guidelines 1996 Drug Therapy course. McGill University. Treatment of Acute myocardial Infarction 1996-1998 Medical Economics course; Division of clinical epidemiology, The Montreal General Hospital,

McGill University

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1995 Grand Rounds at the Royal Victoria Hospital and The Montreal General Hospital, McGill University. Treatment of Myocardial Infarction in the US and Canada

Invited Lectures & Seminars Outside McGill Academic 2008 Hebrew University, Hadassah Hospital, Jerusalem, Israel “ Cardiovascular Outcomes after a Change in

Prescription Policy for Clopidogrel” 2008 Medical Grand Rounds, CHUM La femme et la maladie cardiovasculaire 2007 CCORT II Annual Meeting “Drug Policy Project- Clopidogrel use in Quebec and Ontario” Toronto,

Ontario 2007 Présentation au colloque 2007 du RQRUM, « Quels sont les critères pour préparer une demande de

subvention auprès des différents organismes tels que les IRSC? « Quebec, Quebec 2006 Canadian Society of Interventional Cardiology, Outcomes Post-PCI, Toronto, Ontario 2006 Canadian Society of Internal Medicine, Improving Presentation Skills, Calgary, Alberta 2005 Cardiology Rounds, Sacré-Coeur Hospital, Université de Montréal. ACE/ARB Gender differences in

effectiveness angiotensin converting enzyme inhibitors and angiotensin receptor blockers in women and men with congestive heart failure

2005 IHEA International Health Economics Association, 5th World Congress, Barcelona 2005 2e Symposium et exposition annuels Société Québécoise d’Insuffisance Cardiaque, Hôtel Loews Le

Concorde, Quebec 2006 Canadian Cardiovascular Society, Workshop, Sex and gender determinants of cardiovascular disease:

An overview 2005 Canadian Cardiovascular Society, Workshop, Genetic and environmental interactions in

cardiovascular diseases and disorders 2005 Invited Professor. Mortality rates in elderly patients who take different ACE inhibitors after AMI: A

class effect? Calgary, Alberta 2005 Latin American Forum on Global Cardiovascular Risk, Mexico 2005 Thematic Symposia at the 2nd Annual CIHR National Research Forum for Young Investigators in

Circulatory and Respiratory Health, Winnipeg, Manitoba 2004 Canadian Cardiology Society Workshop, CCORT Atlas on Canadian Variations in Cardiac Care 2003 Canadian Cardiology Society, Workshop 2002 Chair. American College of Cardiology. Quality conference. Washington, D.C. 2002 Canadian Society of Internal Medicine, Research Methods, Nova Scotia 2002 Santé publique de Montréal. Tuberculosis in the homeless: Improving adherence to follow-up and

ionized prophylaxis through incentives, Montreal 2001 Coût-efficience du traitement hypolipidémiant pour la prévention primaire et secondaire de la maladie

cardiovasculaire. Une analyse en population générale. Conférence de santé publique du Québec, Montreal

2001 Canadian Society of Internal Medicine, Chair, Research Session, Banff 2001 Commonwealth Fund, Academy of Health Services Research meeting. Canada-US comparisons

of AMI care, Atlanta 2000 2nd International Conference on Technological Change and Medical Expenditure Growth, Stanford

University, California 2000 Canadian Society of Cardiology; Chair Health Services Research session, Vancouver 2000 Canadian Society of Internal Medicine meeting; Chair of the scientific session. 2000 European Society of Cardiology, Amsterdam, The Netherlands. Treatment of acute myocardial

infarction in the United States and Canada 1999 International Conference on Technological Change and Medical Expenditure Growth, Stanford

University, California. The Canadian approach to AMI treatment 1999 Canadian Institute of Medicine, Montreal. Problems of the young investigator 1998 International Conference on Technological Change and Medical Expenditure Growth, Stanford

University, California

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1998 Cost-effectiveness of lipid lowering drugs. University of Sherbrooke 1998 Symposium on Medical Economics, University of California at Davis, California 1998 Robert Wood Johnson Clinical Scholars meeting, Florida 1995 Grand Rounds at the Cleveland Clinic Foundation. The Canadian-US GUSTO substudy 1993 Advanced International Cardiovascular Epidemiology Seminar (Singapore) 1993 Robert Wood Johnson Clinical Scholars meeting, Florida 1992 Robert Wood Johnson Clinical Scholars meeting, Florida 1992 10 Day International Teaching Seminar on Cardiovascular Epidemiology and Prevention, Sweden 1991 Robert Wood Johnson Clinical Scholars meeting, Florida Lay Public 2008 Publications in L’Actualite and McLean magazine 2007 Newspaper articles published (National Post, Globe and Mail, LaPresse, The Gazette) 2007 Several radio and televised interviews (RDI, TVA, LCN, CJAD, Info 690, CTV) 2007 Publication in CMAJ Supplement 2006 Article published (MUHC News Centre) 2006 Several televised press conferences 2006 Newspaper article published (The Globe and Mail, Le Devoir, La Presse) 1999-2000 Collège André Grasset, Montréal. Women in Medicine 1999 Personnalité de l’année de la Presse en Sciences et Technologie 1998 Personnalité de la semaine de la Presse 1997 Fondation des Maladies du Coeur, Alma, Québec. Le traitement de l’infarctus au Québec 1994-2001 Several televised press conferences (CNN, Radio Canada, and RDI) 1994-2005 Several newspaper articles published about my research findings in local and international

newspapers OTHER CONTRIBUTIONS 1. Journals Editorial Boards 2007 American Heart Journal 2006- Canadian Journal of Cardiology 2002- Co-Editor, The Canadian Cardiovascular Outcomes Research Teams’ Canadian Cardiovascular

Atlas Project 2002, 2004 Guest Editor for the American Heart Journal 1997-2000 Canadian Medical Association Journal 1996- American Heart Journal Ad hoc Reviews 2003- British Medical Journal, Journal of Clinical Epidemiology 2002- Annals of Internal Medicine (ranked in top 30%of reviewers); Circulation 2000- Canadian Journal of Cardiology; Journal of the American Medical Association;

Journal of Free Radical Biology and Medicine; Heart 1997- Canadian Medical Association Journal; New England Journal of Medicine; Medical Care; Chest 1996- American Heart Journal; Journal of the American College of Cardiology Participation in Conference Organization 2002-2009 Organizer, GENESIS ICE team annual meeting 2007- Abstract grader for 13th World Congress on Heart Disease, International Academy of Cardiology 2005-2006 Member of organizing committee, Canadian Society of Internal Medicine Conference, Toronto.

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2004 Session Moderator, Canadian Cardiology Society, Calgary, CA. 2003 Organizer, Cardiovascular Réseau/Clinical Trials Subgroup, Delta Hotel, Montreal, QC 2002 Session Moderator for the American Heart Association, 4th Scientific Forum on Quality of Care and

Outcome Research in Cardiovascular Disease and Stroke 2002 Organizer, Cardiovascular Réseau/Clinical Trials Subgroup, Jewish General Hospital 2001-2004 Abstract grader for the Canadian Cardiovascular Society meeting 2000-2004 Abstract grader and Session Chair for Canadian Society of General Internal Medicine meeting 1999-2000 Abstract grader for American Society of General Internal Medicine meeting 1993 Session Moderator for the American Heart Association 2. Granting Agencies Internal Scientific Evaluator\ 2007 Michael Smith Prize in Health Research, CIHR 2005- Heart and Stroke, Internal Review Committee 2001-2006 Canadian Institutes of Health Research, Health Services Research Fellowship 2001 Heart and Stroke Foundation of Canada, Research Fellowship 2001 Heart and Stroke Foundation of Canada, Career Award Committee 1998-2000 Medical Research Council of Canada, Health Services Research Committee 1998 Fonds de la recherche en santé du Québec/Conseil consultatif en pharmacologie; operating grants External Scientific Evaluator 2007 Alberta Heritage Foundation 2005 Department of Community Health Sciences, University of Calgary 2000 Clinical Trials Committee, Canadian Institutes of Health Research (CIHR) 2000 Interdisciplinary Research Team Program, CIHR 1997 National Health Research and Development Program 1996 British Columbia Health Research Foundation 1996-1997 Medical Research Council of Canada 1996-1998 Heart and Stroke Foundation of Canada 1995-1998 Health Services Research and Epidemiology of the FRSQ program 3. Committees 2009- Member, Allied Health Professionals- Fellowships, Canadian Institutes of Health Research 2008 External Reviewer, Dalhousie University Clinical Scholars program 2008 External Reviewer, Heart and Stroke Foundation of Ontario 2007 Member, Departmental Tenure Committee 2007 Fonds de la recherché en santé du Québec, Member of Finance Committee 2006 Expert Reviewer, Health Care in Canada 2005-2007 McGill Admissions Committee, Department of Epidemiology 2000-2002 Canadian Cardiovascular Outcome Research Steering Committee 2004-2006 McGill Admissions Committee, Faculty of Medicine 2004-2007 Organizing Committee Member, Canadian Society of Internal Medicine 2003- Expert Consultant, Heart and Stroke Foundation of Québec 2002- Member, Board of Directors, Fonds de la recherche en santé du Québec 2002 Internal Reviewer of Vascular Surgery Program at McGill University 2000-2005 Canadian Cardiovascular Outcome Research Steering Committee 2000- Member of the Canadian Society of Internal Medicine research committee 1999-2000 McGill Medical School Accreditation Internal Committee 1997- Internal Medicine Residency Training Committee, The Montreal General Hospital 1995-1999 Montreal General Hospital Ethics Committee

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4. Expert Panels 2007 Canadian Heart Health Strategy-Action Plan 2006 CIHI Health Care in Canada 2006 report 2005-2007 Heart and Stroke Foundation of Canada, Member of the Personal Support Program review 2004 New Brunswick Heart Center Evaluation Team 2002 Canadian Heart Health Strategy and Action Plan 2001 Canadian Cardiovascular Research Team on Quality Indicators for AMI Care, Toronto 2001 Member, Scientific Council, Gestion Recherche Québec (GEREQ), Montreal 5. Professional and/or Learned Societies Fellow, Royal College of Physicians and Surgeons of Canada Member, Collège des médecins du Québec Examiner, Collège des médecins du Québec, Internal Medicine, oral examinations (1996-2002) RESEARCH Peer-Reviewed Grants 2009-2013 Co-investigator: An RCT of women’s adherence to women-only, home-based $ 369,204 and traditional cardiac rehabilitation. (CR4HER) Heart and Stroke Foundation 2008-2013 Co-investigator: Improving prediction of cardiovascular morbidity and mortality $383,559 In men and women using a new nuclear imaging technique designed to assess Endothelial function by vascular reactivity. Canadian Institute of Health Research 2008-2011 Principal Investigator: GENESIS PRAXY (GENdEr and Sex DetermInantS of $ 136,572 Cardiovascular Disease: From Bench to Beyond PRemature Acute Coronary

SYndrome). Heart and Stroke Foundation of Ontario 2008-2011 Principal Investigator: GENESIS PRAXY (GENdEr and Sex DetermInantS of $ to be determined Cardiovascular Disease: From Bench to Beyond PRemature Acute Coronary $47,000/1st year SYndrome). Heart and Stroke Foundation of Nova Scotia 2008-2011 Principal Investigator: GENESIS PRAXY (GENdEr and Sex DetermInantS of $ to be determined Cardiovascular Disease: From Bench to Beyond PRemature Acute Coronary $17,000/1st year SYndrome). Heart and Stroke Foundation of Quebec 2008-2011 Principal Investigator: GENESIS PRAXY (GENdEr and Sex DetermInantS of $ to be determined Cardiovascular Disease: From Bench to Beyond PRemature Acute Coronary $45,747/1st year

SYndrome). Heart and Stroke Foundation of British Columbia 2008 Principal Investigator: GENESIS PRAXY (GENdEr and Sex DetermInantS of $10,000 Cardiovascular Disease: From Bench to Beyond PRemature Acute Coronary SYndrome). Desjardin Sécurité Financière Award for best project on women and heart

disease.

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2008-2011 Co-Investigator. Sex Differences and Determinants of Health Status Post Acute $ 300,000 Myocardial Infarction in Younger Adults. Heart and Stroke Foundation 2008-2010 Co-Investigator. The efficacy of popular diets: A systematic review and $ 100,150

hierarchical bayesian meta-analysis. Fonds de la recherche en santé du Québec 2008-2010 Co-Investigator. Exploring sex differences in the efficacy of cardioprotective $ 150,000 medications: a series of meta-analyses. Canadian Institute of Health Research 2008-2009 Co-Investigator. Sex and Ethnic differences in stroke prognosis and quality of $ 100,000 care. Canadian Institute of Health Research 2008-2009 Co-Investigator. Exploring sex differences in the efficacy of cardioprotective $ 52,000 medications: a series of meta-analyses. Heart and Stroke Foundation of Alberta 2008-2009 Co-Principal Investigator. Effect modification of gene-mediated susceptibility $ 100,000

to myocardial infarction by sex and other conventional coronary risk factors. Canadian Institute of Health Research 2008-2009 Co-Investigator. Integrating Gender into health Research: A scoping $ 68,540

Study on Conceptual Frameworks and Tools for Measuring Gender. Canadian Institute of Health Research 2007-2010 Principal Investigator. A population-based analysis of the effectiveness and $ 353,977

Adverse effects of medications in patients with atrial fibrillation. Canadian Institute of Health Research

2007-2010 Co-Principal Investigator. Timely access to specialized care in men and $ 457,485

women with congestive heart failure: Do we meet nationally established benchmarks? Canadian Institute of Health Research

2007-2010 Co-Investigator. Pharmacogentic and pharmacokinetic variation in CYP2B6 $ 75,000 medications: a series of meta-analyses. Canadian Institute of Health Research 2007-2009 Co-Investigator. From adherence to outcomes: A study of sex differences in $ 120,000

the use and impact of cardioprotective medications in Diabetes. Canadian Institute of Health Research 2007-2009 Co-Investigator. Cardiac outcomes in patients with metabolic syndrome: $ 112,816

A systematic review and hierarchical Bayesian meta-analysis Canadian Institute of Health Research 2006-2011 Co-Investigator. Development, validation and application of new methods $ 572,735 for analysing observational studies of medications. Canadian Institute of Health Research

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2006-2011 Co-Investigator. CIHR Team Grant in Cardiovascular Outcomes Research. $ 4,770,581 Canadian Institute of Health Research 2006-2008 Co-Investigator. Walking behaviour and glycemic control in type 2 diabetes: $ 213,113

seasonal and sex differences. Canadian Institutes of Health Research 2006 Co-Investigator. A hierarchical Bayesian meta-analysis of randomized clinical $ 75,000 trials of behavioural interventions for smoking cessation. CIHR Knowledge Translation and Exchange 2005-2008 Co-Investigator. Recherche évaluative et économique portent $ 253,000 sur la prevention primaire, la prevention secondaire et le traitement

des maladies cardiovascularies. Fonds de la recherche en santé du Québec 2005-2008 Co-Investigator. An economic and quality of life evaluation of bupropion $ 119,400

therapy for smoking cessation in patients following an acute coronary syndrome. Canadian Institutes of Health Research 2005-2006 Co-Principal Investigator. Étude du suivi des patients vus en urgence $ 75,000

hospitalière pour insuffisance cardiaque congestive (IC): Comparaison de ceux qui sont orientés vers les cliniques spécialisées IC et de ceux que ne le sont pas. Canadian Institutes of Health Research

2005-2006 Co-Investigator. A hierarchical Bayesian meta-analysis of randomized $ 41,000 clinical trials of smoking cessation aids. Canadian Institutes of Health Research

2005-2006 Co-Investigator. The safety of transdermal nicotine immediately following $ 50,000 an acute coronary syndrome (STADIA) trial: A pilot study. Canadian Tobacco Control Research Initiative 2004-2007 Principal Investigator. Gender and Sex Determinants of Cardiovascular $ 1,476,247

Disease: From Bench to Beyond. (GENESIS) CIHR/Institutes of Gender and Health and Circulatory and Respiratory Health, the Lung Association, Heart & Stroke Foundation of Canada

2004-2007 Co-Investigator. Zyban as an Effective smoking cessation aid for patients $ 75,000 following an acute coronary syndrome. (ZESCA ) trial. Heart and Stroke Foundation Clinical Trial

2004-2007 Co-Investigator. Development and validation of new statistical methods $213,049 for modeling intermediate events in survival analysis.

Canadian Institutes of Health Research 2004-2007 Principal Investigator. Modern statistical methods to analyze administrative $ 216,875 databases. Canadian Institutes of Health Research 2004-2007 Principal Investigator. A population-based analysis of the effectiveness and $ 331,277

determinants of use of cardiac drugs for congestive heart failure. Canadian Institutes of Health Research

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2004-2007 Co-Investigator. L’Impact du type d’intervention chirurgicale sur l’utilisation $ 192,445 des ressources du système de santé chez les patients porteurs d’une transposition des gros vaisseaux. Fonds de recherche en santé du Québec 2004-2005 Principal Investigator. The cardiovascular effects of selective $ 63,933 cyclooxygenase-2 (COX-2) inhibitors in patients with heart disease. Canadian Institutes of Health Research 2004-2005 Co-Investigator. Post-angiographic rates of abstinence with multiple smoking $ 50,000 cessation aids: The promise trial pilot study. Canadian Tobacco Control Research Initiative 2004-2005 Co-Investigator. Use of perioperative anti-ischemic medical therapy among $ 54,500 patients undergoing abdominal-aortic aneurysm repair. Canadian Institutes of Health Research 2003-2006 Co-Investigator. Zyban as an Effective Smoking Cessation Aid for Patients $ 1,457,900 Following an ACS: The ZESCA Trial. Canadian Institutes of Health Research Randomized Controlled Trial 2003-2006 Co-Principal Investigator. Biais lié au genre dans les cliniques spécialisées $ 384,592

en insuffisance cardiaque : référence, prise en charge, traitement et résultat du service de santé. Canadian Institutes of Health Research

2003-2005 Co-Investigator. Refining methods to assess adherence to multidisciplinary $ 63,736 pain treatment. Social Sciences and Humanities Research Council of Canada

2002-2006 Co-Investigator. Canadian Cardiovascular Outcomes Research Team. $ 1,000,000

Heart and Stroke Foundation of Canada 2002-2006 Co-Investigator. Ėtat de stress aigu et trouble de stress post-traumatique $ 300,000

après infarctus ou arrêt cardiaque: prévalence et conséquences médicales et psychologique. Canadian Institutes of Health Research

2002-2005 Co-Investigator. Impact of socioeconomic status on therapy choice: $ 107,000 NSAID prescriptions and gastrointestinal events. Canadian Institutes of Health

Research 2002-2004 Co-Investigator. Efficacité des médicaments cardiaques après l’infarctus $ 120,000

du myocarde. Fonds de la recherche en santé du Québec (declined) 2002-2004 Principal Investigator. Determinants of variation in the management $ 48,500 of acute myocardial infarction. Heart and Stroke Foundation of Ontario 2002-2004 Principal Investigator. Determinants of variation in the management $ 45,000 of acute myocardial infarction. Heart and Stroke Foundation of Quebec 2002-2004 Principal Investigator. Determinants of variation in the management $ 39,850 of acute myocardial infarction. Heart and Stroke Foundation of British

Columbia and the Yukon

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2002-2004 Principal Investigator. A population-based analysis of the effectiveness $ 96,192 of cardiac drugs after acute myocardial infarction. Canadian Institutes of Health

Research 2002-2004 Principal Investigator. Estimating the effectiveness of invasive and $ 136,000 non-invasive management strategies for acute myocardial infarction using administrative databases. Canadian Institutes of Health Research 2002-2004 Principal Investigator. A population-based study of determinants of $ 89,190 variation in the management of acute myocardial infarction.

Canadian Institutes of Health Research (declined) 2002-2002 Co-Investigator. New perspectives on gender and health competition $ 10,000 Canadian Institutes of Health Research (seed grant)

2001-2006 Co-Investigator. AMI outcomes across provinces. Canadian Cardiovascular $ 4.7 million Outcomes Research Team. Canadian Institutes of Health Research/Interdisciplinary

Health Research Teams 2001-2002 Collaborator. Access to care for vulnerable populations. 24,897 US Technology Change in Health Care (TECH) Research Network Commonwealth Fund, USA 2000-2003 Co-Investigator. Quebec Study of the Adult congenital population study. $ 30,000

Heart and Stroke Foundation of Quebec 2000-2003 Co-Principal Investigator. ROSETTA-CABG Registry. Heart and Stroke $ 36,000 Foundation of Québec 2000-2002 Principal Investigator. Routine vs Selective Exercise Testing After $ 50,000

Coronary Artery Bypass Graft Surgery. Fonds de la recherche de santé du Québec

2000-2002 Co-Investigator. SLE-specific risk factors for coronary disease $ 199,026 and stroke. Canadian Institutes for Health Research

1999-2001 Principal Investigator. A retrospective Study of the Treatment of Acute $ 120,000 Myocardial Infarction in Quebec. Fonds de la recherche en santé du Québec 1999-2001 Co-Principal Investigator. The Non-Q Wave MI Study: A randomized $ 120,000

Clinical Trial. Fonds de la recherche en santé du Québec

1998-2000 Co-Principal Investigator. The Adore Study – Selective versus routine $ 120,000 Use of functional testing after angioplasty. Fonds de la recherche en santé du Québec

1996-1998 Principal Investigator. A prospective cohort study of quality of life after $ 120,000 myocardial infarction. Fonds de la recherche en santé du Québec 1996-1998 Principal Investigator. Use of lipid modifying drugs for the primary and $ 160,000

secondary prevention of coronary heart disease. Fonds de la recherche en santé du Québec/Conseil consultatif en pharmacologie

1996-1998 Principal Investigator. Iron metabolism and coronary artery disease. $ 30,000 Heart and Stroke Foundation of Canada

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1995-2000 Team Member. Group Grant to the Division of Clinical Epidemiology, $ 1,140,000 Montreal General. Fonds de la recherche en santé du Québec Hospital. Fonds de la recherche en santé du Québec Industry 2002-2004 Consultant. Association between NSAIDS, Cox-2 inhibitors and $ 10,000

thromboembolic cardiovascular events. Merck & Co. Inc. 2001-2002 Co-Principal Investigator. Exploratory project on technological change in $ 16,000 US

osteoporosis prevention: International differences in trends and their consequences. Merck Pharma Inc.

2001-2002 Co-Principal Investigator. Association of conventional nonsteroidal $ 5,000 anti-inflammatory drugs with hospitalizations for myocardial infarction. Merck & Co Inc., USA. 2000-2001 Co-Principal Investigator. Cost of myocardial infarction in Canada and $ 12,500 US

the United States (INCCUS) Study. Eclipsys Corporation, USA. 2000-2001 Co-Principal Investigator. Cost of perioperative myocardial ischemic $ 150,000 US

complications. Pfizer, USA. Internal 1996-1997 Principal Investigator. A prospective cohort study of quality of life after $ 10,000 myocardial infarction. The Montreal General Hospital Research Institute PUBLICATIONS (Peer-Reviewed) *Where my students are first authors, I am the senior author (last place).

1. Pilote L, Huttner I, Marpole D, Sniderman A. Stiff left atrial syndrome. Can J Cardiol 1988;4:255-259.

2. Pilote L, Silberberg J, Lisbona, R, Sniderman A. Prognosis in patients with low left ventricular ejection fraction after myocardial infarction: importance of exercise capacity. Circulation 1989;80:1636-1641.

3. Begg CB, Pilote L, McGlave PB. Bone marrow transplantation versus chemotherap0y in acute non-

lymphocytic leukemia: a meta-analytic review. Eur J Cancer Clin Oncol 1989;25:1519-1523. 4. Begg CB, Pilote L. A model for incorporating historical controls into a meta-analysis. Biometrics

1991;47:899-906.

5. Pilote L, Olwitt G, Okugagzhi G, Larson C. Community based nutritional survey, Geruke Jimate peasant's association, Illubabor region, Ethiopia. Ethiop J Health Dev 1991;5:1-4.

6. Pilote L, Thomas RJ, Dennis C, Goins P., Houston-Miller N, Kraemer HC, Leong C, Berger III WE, Lew H,

Heller RS, Rompf J, Debusk RF. Return to work after uncomplicated myocardial infarction: a trial of practice guidelines in the community. Ann Intern Med 1992; 117:383-389.

7. Eisenberg MJ, Pilote L. Pharmacologic stress echocardiography. (letter) Ann Intern Med 1992;117:168-169.

8. Pilote L, Racine N, Hlatky MA. Differences of treatment of acute myocardial infarction in the United States

and Canada, comparison of two university hospitals. Arch Intern Med 1994;154:1090-1096.

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9. Zolopa A, Hahn JA, Gorter R, Miranda J, Wlodarcyzk D, Pilote L, Peterson J, Moss A. HIV and tuberculosis

infection in San Francisco's homeless adults. Prevalence and risk factors in a representative sample. JAMA 1994;272:455-461.

10. Mark DB, Naylor CD, Hlatky MA, Califf RM, Topol EJ, Granger CB, Knight JD, Nelson CL, Lee KL, Clapp-

Channing N, Pryor DB, Sutherland W, Pilote L, Armstrong PW. Use of medical resources and quality of life after acute myocardial infarction in Canada and the United States. N Engl J Med 1994;331:1130-1135.

11. Pilote L, Eisenberg MJ. Prevention of radiocontrast-induced renal insufficiency. [Letter] N Engl J Med

1995;332:1035-1036.

12. Pilote L, Bourassa MG, Bacon C, Hlatky MA. Better functional status in American than in Canadian patients after myocardial infarction: An effect of medical care? J Am Coll Card 1995;26:1115-1120.

13. Pilote L, Califf RM, Sapp S, Miller DP, Mark DB, Weaver WD, Gore JM, Armstrong PW, Ohman EM, Topol

EJ. Regional variation across the United States in the management of acute myocardial infarction. N Engl J Med 1995;333: 565-572.

14. Pilote L, Granger C, Armstrong PW, Mark DB, Hlatky MA. Differences in the treatment of acute myocardial

infarction in the United States and Canada: a physician's survey. Med Care 1995;33:598-610.

15. Pilote L , Hlatky MA. Attitudes of women towards hormone therapy and prevention of heart disease. Am Heart J 1995;129:1237-1238.

16. Pilote L. Helicobacter Pylori: cause or effect for peptic ulcer disease? (letter) Ann Intern Med 1995;122:394-

395.

17. Pilote L, Racine N, Hlatky MA Response to a Letter to the Editor about our article: Treatment of acute myocardial infarction in the United States and Canada: a comparison of two university hospitals. Arch Intern Med 1995;155:335.

18. Pilote L, Miller DP, RM Califf, JS Rao, WD Weaver, EJ Topol. Determinants of use of coronary angiography

and revascularization after thrombolysis for acute myocardial infarction in the United States. N Engl J Med 1996;335:1198-205.

19. Pilote L, Peterson J, Zolopa A, Hahn JA, Schecter G, Moss A. Tuberculosis prophylaxis in the homeless: a trial

to improve adherence to referral. Arch Intern Med 1996;156:161-165. 20. Pilote L, Pashkow F, Thomas J D, Snader CE, Harvey SA, Marwick TH, Lauer MS. Clinical yield and cost of

exercise treadmill testing to screen for coronary artery disease in asymptomatic individuals. Am J Cardiol 1998;81:219-224.

21. McClellan MB, Kessler DP for the TECH Investigators. A global analysis of technological change in health

care: Preliminary report from the TECH Research Network. Health Affairs 1999;18;250-255.

22. Tulsky J, Pilote L, Chesney M, Burke M, Hahn J, Moss A. Adherence to Isoniazid prophylaxis in the homeless. A randomized controlled trial. Arch Int Med 2000;160:697-702.

23. Pilote L, Lavoie F, Ho V, Eisenberg MJ. Changes in the treatment of acute myocardial infarction in Quebec

accompanied by improved survival rates: 1988 through 1995. Can Med Assoc J 2000:163;31-36.

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24. Pilote L, Joseph L, Bélisle P, Van Lente F, Robinson K, Tager IB. Iron stores and coronary artery disease: A clinical application of a method to incorporate measurement error of the exposure in a logistic regression model. J Clin Epi 2000;53:809-816.

25. *Beck C, Joseph L, Bélisle P, Pilote L. Predictors of quality of life 6 months and 1 year after acute myocardial

infarction. Am Heart J 2001;142:271-279.

26. Pilote L. Treating acute myocardial infarction. (letter) Can Med Assoc J 2001;164:323-324.

27. Eisenberg MJ, Schechter D, Lefkovits J, Goudreau E, Deligonul U, Mak KH, Del Core M, Duerr R, Garzon PM, Huynh T, Smilovitch M, Sedlis S, Brown DL, Brieger D, Pilote L. The ROSETTA Investigators. Use of routine functional testing after percutaneous transluminal coronary angioplasty: results from the ROSETTA Registry. Am Heart J 2001;141:837-846.

28. The Technological Change in Health Care (TECH) Research Network. Differences in technological change

around the world: Evidence from heart attack care. Health Affairs 2001;20:25-42.

29. Pilote L, Miller DP, Califf RM, Topol EJ for the GUSTO-I Investigators. Recurrent ischemia after thrombolysis for acute myocardial infarction. Am Heart J 2001;141:559-565.

30. *Beck CA, Lauzon C, Eisenberg MJ, Huynh T, Dion D, Roux R, Racine N, Carignan S, Diodati JG,

Charbonneau F, Lévesque C, Pouliot J, Pilote L. Discharge prescriptions following admission for acute myocardial infarction at tertiary care and community hospitals in Quebec. Can J Cardiol 2001;17:33-40.

31. Rahme E, Pilote L, LeLorier J. Risk of myocardial infarction associated with selective Cox-2 inhibitors:

Questions remain. [Letter] Arch Int Med 2002;162(22):2639-2642.

32. Pilote L. Antibiotics with activity against Chlamydia pneumoniae do not reduce the risk of myocardial infarction in the general population. (Commentary). Evidence-based Cardio Med 2002;6:164-165.

33. *Rodrigues E, Simpson E, Richard H, Pilote L. Regional variation in the management of acute myocardial

infarction in the province of Quebec. Can J Cardiol 2002;18:1067-1076.

34. Pilote L, Beck C, Richard H, Eisenberg MJ. The effects of cost-sharing on essential drug prescriptions, medical care utilization, and outcome after acute myocardial infarction in elderly patients. Can Med Assoc J 2002;167:246-252.

35. Nault P, Irshad K, Pilote L, Trahan L. Le taux d’endartériectomie carotidienne au Québec, a-t-il été influencé

par NASCET, ACAS et les consensus nord-américains. Angiology 2002;54:1-6.s

36. Rahme E, Pilote L, LeLorier J. Association between naproxen use and protection against acute myocardial infarction. Arch Intern Med 2002;162:1111-1115.

37. Pilote L, Lauzon C, Huynh T, Dion D, Roux R, Racine N, Carignan S, Diodati JG, Charbonneau F, Lévesque C,

Pouliot J, Joseph L, Eisenberg MJ. Quality of life after acute myocardial infarction among patients treated at sites with and without on-site availability of angiography. Arch Intern Med 2002;162:553-559.

38. *Doucet M, Eisenberg MJ, Pilote L. Effects of hospital volume on long-term outcomes after percutaneous

transluminal coronary angioplasty following acute myocardial infarction. Am Heart J 2002;144:144-150.

39. Pilote L, Tager IB. Outcomes research in the development and evaluation of practice guidelines. Biomed Central Health Serv Res 2002;2:(1)7.

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40. Pilote L, Green L, Joseph L, Richard H, Eisenberg MJ. Antibiotics against chlamydia pneumoniae and prognosis after acute myocardial infarction. Am Heart J 2002;143:294-300.

41. Eisenberg MJ, Okrainec K, Lefkovits J, Goudreau E, Deligonul U, Mak KH, Duerr R, Tsang J, Huynh T, Sedlis

S, Brown DL, Brieger D, Pilote L and the ROSETTA Investigators. Medical therapy in patients undergoing percutaneous coronary intervention: results form The ROSETTA Registry. Can J Cardiol 2003;19(9):1009-1015.

42. Brox AC, Filion KB, Zhang X, Pilote L, et al. In-hospital cost of abdominal aortic aneurysm repair in Canada

and the United States. Arch Intern Med 2003;163:2500-2504.

43. *Beck C, Penrod J, Gyorkos TW, Pilote L. Does aggressive care following acute myocardial infarction reduce mortality? Analysis and instrumental variables to compare effectiveness in Canadian and United States patient populations. Health Serv Res 2003;38(6):1423-1440.

44. Pilote L, Joseph L, Bélisle P, Penrod J. Universal health insurance coverage does not eliminate inequities in

access to cardiac procedures after acute myocardial infarction. Am Heart J 2003;46(6):1030-1037.

45. Azoulay A, Pilote L, Filion, KB, Eisenberg MJ. Costs of treatment of acute myocardial infarction in Canadian and US hospitals. CVR&R 2003;26:555-560.

46. *Rodrigues EJ, Eisenberg MJ, Pilote L. Effects of early and late administration of angiotensin-converting

enzyme inhibitors on mortality after myocardial infarction. Am J Med 2003;115(6):473-479.

47. *Essebag V, Genest Jr. J, Suissa S, Pilote L. The Nested Case-Control Study in Cardiology. Am Heart J 2003;146:581-590.

48. Tu JV, Austin PC, Filate WA, Johansen HL, Brien SE, Pilote L, Alter DA. Outcomes of acute myocardial

infarction in Canada. Can J Cardiol 2003;19(8):893-901.

49. Pilote L, Saynina O, Lavoie F, McClellan M. Cardiac procedure use and outcomes in elderly patients with acute myocardial infarction in the United States and Quebec, Canada, 1988 to 1994. Med Care 2003 Jul:41(7):813-22

50. *Hudson M, Pilote L. Digoxin for the treatment of heart failure [comment]. [Comment. Letter] N Engl J Med

2003;348:661-663.

51. Tran CT, Lee DS, Flintoft VF, Higginson L, Grant FC, Tu JV, Cox J, Holder D, Jackevicius C, Pilote L, Tanser P, Thompson C, Tsoi E, Warnica W, Wielgosz A. Canadian Cardiovascular Outcomes Research Team/Canadian Cardiovascular Society . Acute Myocardial Infarction Quality Indicator Panel. CCORT/CCS quality indicators for acute myocardial infarction care. Can J Cardiol 2003;19:38-45.

52. *Simpson E, Pilote L. Quality of life after acute myocardial infarction: A systematic review. Can J Cardiol

2003;19:507-511.

53. Tu J, Brien S, Kennedy C, Pilote L, Ghali W, for the Canadian Cardiovascular Outcomes Research Team. An introduction to the CCORT Canadian Cardiovascular Atlas Project – Mapping cardiovascular disease across Canada. Can J Cardiol 2003;19:225-229.

54. Pilote L. More than just hype? (Response). Can Med Assoc J 2003;168:1647-1648.

55. Pilote L. Ramipril use in Canada: HOPE or HYPE? (Editorial). Can Med Assoc J 2003;168:568-569.

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56. *Simpson E, Beck C, Richard H, Eisenberg MJ, Pilote L. Drug prescriptions following acute myocardial infarction: dosage, compliance and persistence. Am Heart J 2003;145:438-444.

57. *Essebag V, Hadjis T, Platt RW, Pilote L. Amiodarone and the risk of bradyarrhythmia requiring permanent

pacemaker insertion. J Am Coll Cardiol 2003;41:249-254.

58. Lauzon C, Beck CA, Huynh T, Dion D, Racine N, Carignan S, Diodati JG, Lévesque C, Charbonneau F, Dupuis R, Pilote L. Depression and prognosis following admission for acute myocardial infarction at tertiary and primary care practice settings. Can Med Assoc J 2003;168:547-552.

59. Grover SA, Ho V, Lavoie F, Coupal L, Zowall H, Pilote L. The importance of indirect costs in primary

cardiovascular disease prevention: can we save lives and money with statins? Arch Intern Med 2003;163: 333-339.

60. Eisenberg MJ, Schechter D, Lefkovits J, Goudreau E, deligonul U, Mak KH, Duerr R, Del Core M, Garzon P,

Huynh T, Smilovitch M, Sedlis S, Brown DL, Brieger D, Pilote L and The ROSETTA Investigators. Utility of routine functional testing after percutaneous transluminal coronary angioplasty: results from THE ROSETTA registry. J Inv Cardiol 2004;16(6):318-322.

61. Chee J, Filion KB, Haider S, Pilote L, Eisenberg MJ. Impact of age on hospital course and cost of coronary

artery bypass grafting. Am J Cardiol 2004;93(6):768-771.

62. Eisenberg MJ, Blankenship JC, Huynh T, Azrin M, Pathan A, Sedlis S, Panja M, Starling MR, Beyar R, Azoulay A, Caron J, Pilote L. Evaluation of routine functional testing after percutaneous coronary intervention. Am J Cardiol 2004;93(6):744-747.

63. Antoniou J, Martineau PA, Filion KB, Haider S, Zukor DJ, Huk OL, Pilote L, Eisenberg MJ. In-Hospital cost

of total hip arthroplasty in Canada and the United States. J Bone Joint Surg Am. 2004;86-A(11):2435-2439.

64. *Karp I, Abrahamowicz M, Bartlett G, Pilote L. Updated Risk Factor Values and the ability of the Multivariable Risk Score to Predict Coronary Heart Disease. Am J Epidemiol 2004;160(7):707-716.

65. *Essebag V, Hadjis T, Platt RW, Abrahamowicz M, Pilote L. Effect of amiodarone dose on the risk of

permanent pacemaker insertion. Pacing Clin Electrophysiol 2004;27(11):1519-25.

66. Pilote L, Abrahamowicz M, Rodrigues E, Eisenberg MJ, Rahme E. Mortality Rates in Elderly Patients Who Take Different Angiotensin-Converting Inhibitors after Acute Myocardial Infarction: A Class Effect? Ann Intern Med 2004;141(2):102-112.

67. Pilote L, Merrett P, Karp I, Alter D, Austin P, Cox J, Johansen H, Ghali W, Tu J. Cardiac procedures after an

acute myocardial infarction across nine Canadian provinces. Can J Cardiol 2004; 20(5):491-500.

68. Pilote L, Beck CA, Karp I, Alter D, Austin P, Cox J, Humphries K, Jackevicius C, Richard H, Tu, JV. For the Canadian Cardiovascular Outcomes Research Team. Secondary prevention after acute myocardial infarction in four Canadian provinces, 1997-2000. Can J Cardiol 2004;20(1):61-67.

69. Gioia LC, Filion KB, Haider S, Pilote L, Eisenberg MJ. Hospital readmissions following abdominal aneurysm

repair. Ann Vasc Surg, Jan 2005;19(1):35-41.

70. Pilote L, Abrahamowicz M. Angiotensin-converting enzyme inhibitors after acute myocardial infarction. Ann Intern Med Jan 2005;142(1):78-79 [Letter].

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71. *Essebag V, Platt RW, Abrahamowicz M, Pilote L. Comparison of nested case-control and survival analysis methodologies for analysis of time-dependent exposure. BMC Med Res Methodol January 2005;5(1):5.

72. *Simpson E, Pilote L. Quality of life after acute myocardial infarction: A comparison of diabetic versus non-

diabetic acute myocardial infarction patients in Quebec acute care hospitals. Health Quality Life Outcomes 2005;3:80:1-6.

73. Bestawros A, Filion KB, Guo T, Haider S, Pilote L, Eisenberg MJ. Coronary artery bypass graft surgery: Do

women cost more? Can J Cardiol 2005;21(13)1195-1200. 74. Gitman M, Okrainec K, Nguyen H, Duerr R, Del Core M, Fourchy D, Huynh T, Lader E, Rogers FJ, Chaudhry

MR, Pilote L, Eisenberg MJ. Impact of diabetes on 12-month outcomes following coronary artery bypass graft surgery: Results from the ROSETTA-CABG registry. Can J Cardiol 2005;21(13)1169-1174.

75. Cox JL, Ramer SA, Lee DS, Humphries K, Pilote L, Svenson L, Tu JV, Canadian Cardiovascular Outcomes

Research Team Investigators. Pharmacological treatment of congestive heart failure in Canada: a description of care in five provinces. Can J Cardiol 2005;21(4):337-343.

76. *Zhou Z, Rahme E, Abrahamowicz M, Pilote L. Survival bias associated with time-to-treatment initiation in

drug effectiveness evaluation: A comparison of methods. Am J Epidemiol 2005;162(10):1016-1023. 77. *Beck C, Richard H, Tu JV, Pilote L for the Canadian Cardiovascular Outcomes Research Team.

Administration data feedback for effective cardiac treatment (AFFECT): A cluster randomized trial. JAMA 2005;294(3):309-317.

78. Pilote L, Lavoie, F, Coupal L, Zowall H, Ho V, Grover SA. Cost-effectiveness of lipid-lowering treatment

according to lipid level. Can J Cardiol 2005;21(8):681-687. 79. *Hudson M, Rahme E, Baron M, Pilote L. Ibuprofen may abrogate the benefits of aspirin when used for the

secondary prevention of myocardial infarction. J Rheumatol 2005;32(8):1589-1593. 80. Eisenberg MJ, Filion KB, Azoulay A, Brox AC, Haider S, Pilote L. Outcomes and costs of coronary artery

bypass graft surgery in Canada and the United States. Arch Intern Med 2005;165(13):1506-1513. 81. *Hudson M, Pilote L, Richard H. Differences in outcomes of patients with congestive heart failure prescribed

celecoxib, rofecoxib, or non-steroidal anti-inflammatory drugs: Population-based study Br Med J 2005;330(7504):1370-1375.

82. Eisenberg MJ, Teng, FF, Chaudhry MR, Ortiz J, Sobkowski,W, Ebrahim I, Saligrama RS, Serio K, Lader E,

Pilote L for the NQWMI Investigators. Impact of invasive management versus non-invasive management on functional status and quality of life following non-Q-wave myocardial infarction: A randomized clinical trial. Am Heart J 2005;149(5):813-819.

83. *Zhou Z, Rahme E; Abrahamowicz M, Tu JV, Eisenberg MJ, Humphries K, Austin PC, Pilote L. Effectiveness

of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of a class effect. Can Med Assoc J 2005;172(9):1187-1194.

84. *Okrainec K, Platt R, Pilote L, Eisenberg MJ. Cardiac medical therapy in patients after undergoinig coronary

artery bypass graft surgery. J Am Coll Cardiol 2005;45(2):177-184. 85. *Sheppard R, Behlouli H, Richard H, Pilote L. Effect of Gender on the Treatment, Resource Utilization and

Outcomes in Congestive Heart Failure in Quebec Canada. Am J Cardiol 2005;95(8):955-959.

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86. *Buresly K, Eisenberg MJ, Zhang X, Pilote L. Bleeding complications associated with combinations of aspirin, thienopyridine derivatives, and warfarin in elderly patients following acute myocardial infarction. Arch Intern Med 2005;165(7):784-789.

87. *Beck C, Eisenberg MJ, Pilote L. Invasive versus non-invasive management of ST-elevation acute myocardial infarction: a review of randomized controlled trials and observational studies. Am Heart J 2005;149(2):194-199.

88. Sariran M, Cugno S, Blankenship J, Huynh T, Sedlis S, Starling M, Pilote L, Wilson B, Eisenberg MJ. Routine

versus selective functional testing after Percutaneous coronary intervention in patients with diabetes mellitus. J Inv Cardiol 2005;17(1):25-29.

89. *Halabi AR, Beck C, Richard H, Eisenberg MJ, Pilote L. Impact of on-site of cardiac catheterization on

resource utilization and fatal and non-fatal outcomes after acute myocardial infarction. BMC Health Serv Res. 2006, 6:148.

90. Dasgupta K, O'Loughlin J, Shunfu C, Karp I, Paradis G, Tremblay J, Hamet P, Pilote L. Emergence of sex

differences in prevalence of high systolic blood pressure: analysis of a longitudinal adolescent cohort. Circulation 2006;114(24):2663-70.

91. Kurzencwyg D, Filion KB, Pilote L, Nault P, Platt RW, Rahme E, Steinmetz O, Eisenberg MJ. Cardiac medical

therapy among patients undergoing abdominal aortic aneurysm repair. Ann Vasc Surg 2006;20(5):569-76. 92. Violette PD, Filion KB, Haider S, Pilote L, Eisenberg MJ. A cost analysis of nonelective coronary artery bypass

graft surgery. J Card Surg 2006;21(6):621-7. 93. *Kosseim M, Mayo N, Scott S, Hanley JA, Brophy J, Gagnon B, Pilote L. Ranking hospitals according to acute

myocardial infarction mortality: Should transfers be included? Med Care 2006;44(7):664-670. 94. *Okrainec K, Pilote L, Platt R, Eisenberg MJ. Use of cardiovascular medical therapy among patients undergoing

coronary artery bypass graft surgery: results from the ROSETTA-CABG registry. Can J Cardiol. 2006;22(10):841-7.

95. ROSETTA-CABG Registry; Wou K, Nguyen H, Duerr R, Del Core M, Fourchy D, Huynh T, Lader E, Rogers

FJ, Chaudhry R, Pilote L, Eisenberg MJ. Impact of functional testing results on prescription patterns of anti-anginal medication after coronary artery bypass graft surgery: results from the ROSETTA-CABG Registry. J Invasive Cardiol. 2006;18(6):278-82.

96. ROSETTA-CABG Registry, Eisenberg MJ, Wou K, Nguyen H, Duerr R, Del Core M, Fourchy D, Huynh T,

Lader E, Rogers FJ, Chaudry R, Okrainec K, Pilote L. Lack of benefit for routine functional testing early after coronary artery bypass graft surgery: results from the ROSETTA-CABG Registry. J Inv Cardiol 2006;18(4):147-152.

97. Wou K, Nguyen H, Duerr R, Del Core M, Fourchy D, Huynh T, Lader E, Rogers FJ, Chaudhry R, Pilote L,

Eisenberg MJ. Impact of functional testing results on prescription patterns of anti-anginal medication after coronary artery bypass graft surgery: Results from the ROSETTA-CABG registry. J Inv Cardiol 2006;18(6):278-282.

98. *Segal R and Pilote L. Warfarin interaction with matricaria chamomilla. [case-report] Can Med Assoc J

2006;174(9):1281-1282. 99. Eisenberg MJ, Wou K, Nguyen H, Duerr R, Del Core M, Fourchy D, Huynh T, Lader E, Rogers RJ, Chaudhry

R, Okrainec K, Pilote L for the ROSETTA-CABG Investigators. Use of stress testing early after coronary artery bypass graft surgery. Am J Cardiol 2006;97:810-816.

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100. *Zhou Z, Rahme E, Pilote L. Association between time of statin initiation after hospital discharge from acute myocardial infarction and risk of recurrence and mortality in elderly patients. Am J Cardiol 2006;97(2):155-159.

101. *Zhou Z, Rahme E, Pilote L. Are Statins Created Equal? - Evidence from Randomized Trials of Pravastatin, Simvastatin and Atorvastatin for Cardiovascular Disease Prevention. Am Heart J 2006;151(2):273-81.

102. Marelli AJ, Mackie AS, Ionescu-Ittu R, Rahme E, Pilote L. Congenital heart disease in the general population:

changing prevalence and age distribution. Circulation 2007 Jan 16;115(2):163-72. 103. Dasgupta K, Chan C, Da Costa D, Pilote L, De Civita M, Ross N, Strachan I, Sigal R, Joseph L. Walking

behaviour and glycemic control in type 2 diabetes: seasonal and gender differences-Study design and methods. Cardiovasc Diabetol. 2007 Jan 15;6:1.

104. Pilote L, Dasgupta K, Guru V, Humphries KH, McGrath J, Norris C, Rabi D, Tremblay J, Alamian A, Barnett

T, Cox J, Ghali WA, Grace S, Hamet P, Ho T, Kirkland S, Lambert M, Libersan D, O’Loughlin J, Paradis G, Petrovich M, Tagalakis V. A comprehensive view of sex-specific issues related to cardiovascular disease. CMAJ 2007 Mar 13;176(6):S1-44.

105. Pilote L, for the GENESIS Investigators. Sex-specific issues related to cardiovascular disease: a synopsis of the

2007 suppliement. CMAJ 2007 Mar 13;176(6):789-91. 106. Mackie AS, Pilote L, Ionescu-Ittu R, Rahme E, Marelli AJ. Healthcare resource utilization in adults with

congenital heart disease: A population-based study. Am J Cardiol. 2007 Mar 15;99(6):839-43. 107. Eisenberg MJ, Lauzon C, Huynh T, Eisenhauer M, Mak KH, Blankenship JC, Doucet M, Wilson B, Pilote L.

Routine functional testing after percutaneous coronary intervention: Results of the aggressive diagnosis of restenosis in high risk patients (ADORE II Trial). Acta Cardiologica. 2007 Apr:62(2):143-50.

108. *Hudson M, Rahme E, Richard H, Pilote L. The risk of congestive heart failure with non-steroidal anti-

inflammatory drugs and selective cyclooxygenase-2 inhibitors – A class effect? Arthritis Rheum. 2007 Apr 15;57(3):516-23.

109. *Hudson M, Humphries K, Tu JV, Behlouli H, Sheppard R, Pilote L. Angiotensin receptor blockers in heart

failure: A class effect? Pharmacotherapy. 2007 Apr;27(4):526-34. 110. *Keyhan G, Chen S-F, Pilote L. The effectiveness of angiotensin-converting enzyme inhibitors in women with

congestive heart failure. Eur J Heart Fail. 2007 Jun-Jul;9(6-7):594-601 111. Norris CM, Hegadoren K, Pilote L. Depression symptoms have a greater impact on the 1-year health-related

quality of life outcomes of women post-myocardial infarction compared to men. Eur J Cardiovasc Nurs. 2007 Jun;6(2):92-8.

112. *Hudson M, Rahme E, Behlouli H, Sheppard R, Pilote L. Sex differences in the effectiveness of angiotensin

receptor blockers and angiotensin converting enzyme inhibitors in patients with congestive heart failure – A population based study. Eur J Heart Fail. 2007 Jun-Jul:6(6-7):602-9.

113. *Keyhan G, Chen S-F, Pilote L. The effectiveness of β-blockers in women with congestive heart failure. J Gen

Intern Med. 2007 Jul:22(7):955-61. 114. Pilote L, Tu JV, Humphries K, Belhouli H, Belisle P, Austin PC, Joseph L. Socioeconomic status, access to

health care and outcomes after acute myocardial infarction in Canada’s universal health system. Med Care. 2007 Jul;45(7):638-646

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115. *Hudson M, Richard H, Pilote L. Parabolas of medication use and discontinuation after myocardial infarction? Are we closing the treatment Gap? Pharmacoepidemiology and Drug Safety. 2007 Jul;16(7):773-785

116. *Azoulay A, Doris N M, Filion K B, Caron J, Pilote L, Eisenberg M J. The Use of the Transition Cost

Accounting System in Health Services Research. Cost Eff Resour Alloc. 2007 Aug 8;5(1):11 117. *Filion KB, Pilote L, Rahme E, Eisenberg MJ. Perioperative use of cardiac medical therapy among patients

undergoing coronary artery bypass graft surgery: a systematic review. Am Heart J 2007 Sep;154(3):407-14. 118. *Karp I, Topol E, Pilote L. Population attributable fraction: its implications for genetic epidemiology and

illness prevention. Am Heart J 2007 Oct;154(4):607-9. 119. Morin S, Rahme E, Behlouli H, Tenenhouse A, Goltzman D, Pilote L.Effectiveness of antiresorptive agents in

the prevention of recurrent hip fractures. Osteoporos Int. 2007 Dec;18(12):1625-32. 120. *Houde S, Feldman DE, Pilote L, Beck EJ, Giannetti N, Frenette M, Ducharme A. Are there sex-related

differences in specialized multidisciplinary congestive heart failure clinics? Can J Cardiol. 2007 ;23(6);451-455 121. *Karp I, Chen S-F, Pilote L. Sex differences in the effectiveness of statins in patients after myocardial

infarction. CMAJ 2007;176(3):333-8. 122. *Hudson M, Rahme E, Richard H, Pilote L. Comparison of measures of medication persistency using a

prescription drug database. Am Heart J 2007;153(1):59-65. 123. Rinfret S, Abrahamowicz M, Tu JV, Humphries K, Eisenberg MJ, Richard H, Austin PC, Pilote L. A

population-based analysis of the class effect of beta-blockers after myocardial infarction. Am Heart J. 2007;153(2):224-30.

124. Pilote L, Beck C, Eisenberg M, Humphries K, Joseph L, Penrod J, Tu V. Comparing Invasive and Non-invasive

Management Strategies for Acute Myocardial Infarction Using Administrative Databases. Am Heart J 2008 Jan;155(1):42-8

125. Demers V, Melo M, Jackeviscius C, Cox J, Kalavrouziotis D, Rinfret S, Humphries K, Johansen H, Tu J, Pilote

L. Comparison of provincial prescription drug plans and the impact on patients’ annual drug expenditures. CMAJ 2008;178(4):405-9.

126. *Karp I, Abrahamowicz M, Fortin P, Pilote L, Neville C, Pineau C, Esdaile J. Recent corticosteroid use and

recent disease activity: Are they independent determinants of coronary heart disease risk factors in systemic lupus erythematosus. Arthritis Rheumatism 2008 Jan 31;59(2):169-175.

127. Balashov K, Feldman D, Savard S, Houde S, Freneete M, Ducharme A, giannetti N, Michel C, Pilote L. Percent

Predicted Value for the Six-Minute Walk Test: Using norm-referenced equations to characterize severity in persons with CHF. J of Cardiac Fail 2008 Feb;14(1):75-81.

128. Humphries KH, Pu A, Carere RG, Pilote L. Angina with ‘normal’ coronary arteries – Sex differences in

outcomes. Am Heart J 2008 Feb;155(2):375-81.

129. Rinfret S, Behlouli H, Eisenberg M, Humphries K, Tu J, Pilote L. Class Effects of Statins in Elderly Patients with Congestive Heart Failure: A Population-Based Analysis. Am Heart J 2008 Feb;155(2):316-23.

130. Mackie AS, Ionescu-Ittu R, Pilote L, Rahme E, Marelli AJ. Hospital Readmissions in Children with Congenital

Heart Disease: A population-based study. Am Heart J 2008 Mar;155(3):577-84.

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131. Seda O, Tremblay J, Gaudet D, Brunelle PL, Gurau A, Merlo E, Pilote L, Orlov SN, Boulva F, Petrovich M, Kotchen T, Cowley AW, Hamet P. Systematic Genome-Wide Sex Specific Linkage of Cardiovascular traits in French-Canadians. Hypertension 2008 Apr;51(4):1156-62.

132. *Karp I, Behlouli H, LeLorier J, Pilote L. Statins and Cancer Risk. Am J Med . 2008 Apr;121(4):302-9.

133. *Karp I, Behlouli H, LeLorier J, Pilote L. Statins and Cancer Risk: decrease or increase. Am J Med. 2008 Apr;121(4):302-9.

134. Pilote L, Abrahamowicz M, Eisenberg MJ, Humphries K, Behlouli H, Tu JV Effect of different angiotensin-

converting-enzyme inhibitors on mortality among elderly patients with congestive heart failure. CMAJ. 2008 May 6;178(10):1303-11.

135. Filion KB, Pilote L, Rahme E, Eisenberg MJ.Use of perioperative cardiac medical therapy among patients

undergoing coronary artery bypass graft surgery. J Card Surg. 2008 May-Jun;23(3):209-15.

136. Shier I, Boivin JF, Platt R, Steele R, Brophy JM, Carnevale F, Eisenberg MJ, Furlan A, Kakuma R, MacDonald ME, Pilote L, Rossignol M. The interpretation of meta-analysis: an objective or subjective process. BMC Medical Informatics and Decision Making. 2008 May 21;8:19.

137. Rabi DM, Khan NA, Vallee M, Hladunewich MA, Tobe SW, Pilote L. Reporting of sex-based analyses in

clinical trials of ACE Inhibitor and Angiotensin Receptor Blocker Efficacy. Can J Cardiol. 2008 Jun;24(6):491-6.

138. Eisenberg M, Filion K, Yavin D, Bélisle P, Mottillo S, Joseph L, Gervais A, O’Loughlin J, Paradis G, Rinfret S,

Pilote L. Pharmacotherapies for smoking cessation: A meta-analysis of randomized controlled trials. CMAJ 2008 Jul 15;179(2):135-44.

139. Norris CM, Hegadoren KM, Patterson L, Pilote L. Sex differences in prodromal symptoms of patients with

acute coronary syndrome: a pilot study. Prog Cardiovasc Nurs. 2008 Winter;23(1):27-31.

140. Mottillo S, Filion KB, Bélisle P, Joseph L, Gervais A, O'Loughlin J, Paradis G, Pihl R, Pilote L, Rinfret S, Tremblay M, Eisenberg MJ. Behavioural interventions for smoking cessation: a meta-analysis of randomized controlled trials. Eur Heart J 2009 Mar;30(6):718-30.

141. Loucks E, Lynch J, Pilote L, Fuhrer R, Almeida N, Richard H, Agha G, Murabito J, Benjamin EJ. Life Course

Socioeconomic Position and Incidence of Coronary Heart Disease: the Framinghan Study. Amercian Journal of Epidemiology 2009 Apr 1;169(7):829-36.

142. Marelli AJ, Therrien J, Mackie AS, Ionescu-Ittu R, Pilote L. Planning the specialized care of adult congenital

heart disease patients: from numbers to guidelines; an epidemiologic approach. Am Heart J. 2009 Jan;157(1):1-8.

143. Jackevicius C, Tu J, Demers V, Melo M, Cox J, Rinfret S, Kalavrouziotis D, Johansen H, Behlouli H, Newman

A, Pilote L. Cardiovascular Outcomes with Removal of Clopidogrel Prior Authorization in Patients Receiving Coronary Stents Post-Myocardial Infarction. New England Journal of Medicine 2008 Oct 23;359(17):1802-10.

144. Ionescu-Ittu R, Marelli A, Mackie AS, Pilote L. Prevalence of severe congenital heart disease after folic acid

fortification of grain products: a time trend analysis in Quebec, Canada. BMJ 2009 May 12;338:b1673.

145. Mackie A, Ionescu-Ittu R, Therrien J, Pilote L, Abrahamowicz M, Marelli A. Children and Adults with Congenital Heart Disease Lost to Follow-up: Who and When? Circulation 2009 Jul 28;120(4):302-9.

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146. Jackevicius C, Cox JL, Carreon D, Tu JV, Rinfret S, So D, Johansen H, Kalvrouziotis D, Demers V, Humphries K, Pilote L. Long-Term Trends in Cardiovascular Medication Utilization and Exprenditures in Canada. CMAJ 2009 Jul 7;181(1-2):E19-28.

147. Tu J, Nardi L, Fang J, Liu J, Khalid L, Johansen H, Canadian Cardiovascular Outcomes Research Team.

National trends in rates of death and hospital admissions related to acute myocardial infarction, heart failure and stroke, 1994-2004. CMAJ 2009;180(13):E120-E7.

148. Perelman J, Shmueli A, McDonald K, Pilote L, Saynina O, Closon MC. Inequality in treatment use among

elderly patients with acute myocardial infarction: USA Belgium and Quebec. BMC Health Serv Res. 2009 Jul 30;9(1):130.

149. Lee DS, Chiu M, Manuel DG, Tu K, Wang X, Austin PC, Mattern MY, Mitiku TF, Svenson LW, Putnam W,

Flanagan WM, Tu JV; Canadian Cardiovascular Outcomes Research Team. Trends in risk factors for cardiovascular disease in Canada: temporal, socio-demographic and geographic factors. CMAJ. 2009 Aug 4;181(3-4):E55-66

150. Thanassoulis G, Karp I, Humphries K, Tu J, Eisenberg M, Pilote L. Impact of Restrictive Prescription Plans on

the Use of Heart Failure Medications. Circulation: Cardiovascular Quality and Outcomes. Circulation Cardiovasc Qual Outcomes. 2009;2:484-490.

151. Abourbih S, Filion KB, Joseph L, Schiffrin EL, Rinfret S, Poirier P, Pilote L, Genest J, Eisenberg MJ. Effect of

Fibrates on Lipid Profiles and Cardiovascular Outcomes: A Systematic Review of Randomized Controlled Trials. American Journal of Medicine 2009 Oct;122(10):962.e1-8.

152. Thanassoulis G, Brophy J, Richard H, Pilote L. The Effect of Gout and Allopurinol Use on Heart Failure

Outcomes. JAMA (Accepted)

153. Khairy P, Ionescu-Ittu R, Mackie A, Pilote L, Marelli A. Changing mortality in Congenital Heart Disease. New England Journal of Medicine (Accepted)

154. Bouchardy J, Therrien J, Pilote L, Ionescu-Ittu R, Martucci G, Bottega N, Marelli AJ. Atrial Arrhythmias in

Adults with Congenital Heart Disease. Circulation (Accepted)

155. Feldman D, Ducharme A, Frenette M, Giannetti N, Michel C, Grondin F, Sheppard R, Behlouli H, Pilote L. Factors related to time admission to specialized multidisciplinary clinics in patients with congestive heart failure. Can J Cardiol 2009;25(10):e347-e352.

Manuscripts Submitted

1. Vallée M, Mayo N, Behlouli H, Pilote L. Incidence, Prevalence and the risk of developing hypertension from

1988 to 2003 in Quebec: A population-based study. 2. Thombs M, Ziegelstein R, Jonge P, Grace S, Pilote L, Dozois D, Beck A, Fuss S, Stewart D, Ormel J, Dobson

K, Abbey S. Does Patient Misattribution of Somatic Symptoms to Depression Account for High Rates of Depressive Symptoms in Heart Disease? Archives of General Psychiatry

Book Chapters

1. Pilote L, For Acute Coronary Syndromes, editor Eric J. Topol, Chapter 16: Treatment of Acute Myocardial

Infarction: International and Regional Differences. Marcel Dekker, New York-based, Hong Kong, 2000.

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2. Pilote L, For Acute Coronary Syndromes, editor Eric J. Topol, Chapter 16: Treatment of Acute Myocardial Infarction: International and Regional Differences. 2nd Edition. Marcel Dekker, New York-based, Hong Kong, 2001

3. Pilote L, Lavoie F, Ho V, Eisenberg M. For A global analysis of technological change in health care: heart

attacks, McLellan M. and Kessler D., eds. Chapter 4: Treatment of Acute Myocardial Infarction in Québec between 1987 and 1995. Ann Arbor, University of Michigan Press, 2002.

4. Pilote L, For Acute Coronary Syndromes, editor Eric J. Topol, Chapter 16: Treatment of Acute Myocardial

Infarction: International and Regional Differences. Chapter 30. 3rd edition. Marcel Dekker, New York 2005.

Abstracts

1. Pilote L, Armstrong P, Granger C, Hlatky MA. Physician treatment of acute myocardial infarction differs between the United States and Canada. Circulation 1992;86:I-39. Presented to the American Heart Association (Anaheim).

2. Racine N, Pilote L, Huynh T, Stewart S, Hlatky M. Myocardial infarction management in Canada and the

United States: A comparison of two hospitals. J Am Coll Cardiol 1992;19:133A. Presented to the American College of Cardiology (Dallas).

3. Mark DB, Naylor CD, Califf RM, Hlatky MA, Granger C, Clapp-Channing N, Knight JD, Sutherland W, Pilote

L, Armstrong PW. Less Catheterization and revascularization following myocardial infarction in Canada is associated with more angina: Initial results from the Canadian-U.S. GUSTO substudy. Circulation 1993;88:I-479. Presented to the American Heart Association (Anaheim).

4. Peterson J, Pilote L, Zolopa A. Moss A. Insights from the street: Peer Health Advisors and medical care in the

Homeless. Clin Res 1993;41:585A. Presented to the Society of Internal Medicine (Washington). 5. Pilote L, Peterson J, Zolopa A, Moss A. Improved adherence to screening for TB and HIV in a homeless

population. Clin Res 1993;41:589A. Presented to the Society of Internal Medicine (Washington). 6. Pilote L, Hlatky MA. Secular changes in the treatment of myocardial infarction between 1987 and 1992. J Am

Coll Cardiol 1993;21:105A. Presented to the American College of Cardiology (Atlanta).

7. Pilote L, Bourassa MG, Bacon C, Hlatky MA. Better functional status in American than in Canadian patients after myocardial infarction: An effect of medical care? Circulation 1994;90:1115-1124. Presented to the American Heart Association (Dallas).

8. Pilote L, Peterson J, Zolopa A, Hahn JA, Moss A. Health Access for the homeless: the user's perspective. J Gen

Int Med 1994;9:107 Suppl 2. 9. Pilote L, Hlatky MA. Hormone replacement after menopause: importance of heart disease in women's decision

making. J Am Coll Cardiol 1994;51A. Presented to the American College of Cardiology (Atlanta).

10. Pilote L, Lauer M, Pashkow F, Marwick, Thomas J. The clinical value and cost of screening exercise treadmill testing in asymptomatic individuals. J Am Coll Cardiol 1995;February:389A. Presented to the American College of Cardiology (New Orleans).

11. Pilote L, Stebbins A, Mark DB, Califf RM, Topol EJ for the GUSTO investigators. Regional variations in the

use of cardiac procedures after thrombolysis: New England is an outlier in the GUSTO trial. J Am Coll Cardiol 1995; February:343A. Presented to the American College of Cardiology (New Orleans).

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12. Eisenberg MJ, Keeler GP, Pilote L. Regional variation of medical therapy in patients undergoing percutaneous coronary revascularization in the United States. Circulation 1995;92(Suppl 1):I-43. Presented to the American Heart Association (Anahein).

13. Pilote L, Sapp S, Miller DP for the GUSTO-I Investigators. Procedures and outcomes among patients with

acute myocardial infarction admitted to hospitals with and without cardiac catheterization laboratories. Circulation 1995;92:I-120. Presented to the American Heart Association (Anahein).

14. Eisenberg MJ, Pilote L, Keeler G, Califf RM, Topol EJ for the CAVEAT investigators. Inadequate pre-hospital

medical therapy in patients undergoing percutaneaous coronary revascularisation: Results from the CAVEAT trial. J Am Coll Cardiol 1995;25:313A. Presented to the American College of Cardiology (New Orleans).

15. Pilote L, Ohman M, Miller DP, Topol EJ for the GUSTO-I Investigators. Recurrent ischemia after thrombolysis for myocardial infarction is frequent, somewhat predictable, and pre-empted by early coronary angiography. J Am Coll Cardiol 1996; February: 249-A. Presented to the American College of Cardiology (Orlando).

16. Pilote L, Miller DP, Califf RM, Sunil R, Topol EJ for the GUSTO-1 Investigators. Classification and regression

tree models to delineate the use of coronary angiography and revascularization after thrombolysis for acute myocardial infarction. J Am Coll Cardiol 1996; February: 245A. Presented to the American College of Cardiology (Orlando).

17. Pilote L, Lavoie F, Saynian O, Eisenberg MJ, McClellan M. Procedures and outcomes for the treatment of the

Elderly with acute myocardial infarction in the United States and Canada between 1988 and 1994. Circulation 1998;98(Suppl 1):I-195. Presented to the American Heart Association (Dallas).

18. *Azoulay A, Eisenberg MJ, Pilote L. Cost of treatment of acute myocardial infarction in the United States and

Canada. J Am Coll Cardiol 1999;(Suppl A):33:307A. Presented to the American College of Cardiology (Atlanta).

19. Pilote L, Lauzon C, Huynh T, Dion D, Roux R, Racine N, Carignan S, Diodati JG, Charbonneau F, Levesque C,

Pouliot J, Joseph L. Quality of life after acute myocardial infarction in patients treated at sites with and without catheterization laboratories. Circulation 1999(Supp 1):100:I-806. Presented to the American College of Cardiology (Atlanta).

20. *Doucet M, Eisenberg MJ, Joseph L, Pilote L. The effect of hospital volume on long-term outcome after

percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 2000;35(Suppl A):12-13A. 21. Pilote L, Joseph L, Bélisle P, Penrod J. Universal health insurance coverage does not eliminate inequities in

access to cardiac procedures after acute myocardial infarction. Can J Cardiol, October 30, 2000. Presented to the Canadian Cardiovascular Society (Vancouver).

22. Pilote L, Lauzon C, Pilote L,, Huynh T, Dion D, Roux R, Racine N, Carignan S, Diodati JG, Charbonneau F,

Lévesque C, Pouliot J, Joseph L, Eisenberg MJ. A prospective cohort study of quality of life after acute myocardial infarction at sites with and without coronary angiography. Can J Cardiol 2000;16(Suppl F):205F. Presented to the Canadian Cardiovascular Society, October 30, 2000. (Vancouver).

23. Pilote L, Ho V, Lavoie F, Coupal L, Zowall Z, Grover SA. Cost-effectiveness of lipid-lowering treatment for the

primary and secondary prevention of cardiovascular disease: a population-based analysis. Can J Cardiol, October 30, 2000. Presented to the Canadian Cardiovascular Society (Vancouver).

24. *Doucet M, Eisenberg MJ, Pilote L. Relationship between institutional volume and long-term outcome after

PTCA. J Am Coll Cardiol 2000;35(Suppl A):12A. Presented to the American College of Cardiology (Anaheim).

29

25. Rahme E, Pilote L, LeLorier J. Association of conventional nonsteroidal antiinflammatory drugs (NSAIDS)

with hospitalizations for myocardial infarction. Arthritis Rheum 2001;44:S266. 26. Puri R, Eisenberg MJ, Sedlis S, Azrin M, Gilbert AZ, Smilovitch M, Pilote L. Routine functional testing

following single and multi-lesion percutaneous coronary interventions: Results from the ADORE trial. Circulation 2001;17 (Suppl II):II-734. Presented to the American Heart Association, (Anaheim).

27. *Simpson EA, Beck CA, Richard R, Rodrigues, Pilote L, Eisenberg MJ. Evidence-based drug prescriptions

post-acute myocardial infarction: prescription combinations, compliance and persistence. Circulation 2001;17 (Suppl II):II-838. Presented to the American Heart Association, (Anaheim).

28. *Beck C, Joseph L, Eisenberg MJ, Huynh T, Diodati JG, Racine N, Charbonneau F, Lévesque C, Lauzon C, Carignan S, Dion D, Roux R, Pouliot J, Pilote L. Predictors of quality of life 6 months and 1 year after acute myocardial infarction. Clin Invest Med 2001;24:276-277. Presented to the Canadian Society of Internal Medicine (Banff).

29. *Halabi AR, Eisenberg MJ, Richard H, Beck, CA, Pilote L. Impact of on-site availability of cardiac

catheterization on cardiac procedure use and quality of life after acute myocardial infarction. Can J Cardiol 2001;17;152C. Presented to the Canadian Cardiovascular Congress 2001, (Halifax).

30. *Rodrigues EJ, Simpson E, Richard H, Pilote L. Regional variation in the management of acute myocardial

infarction in the province of Quebec. Can J Cardiol 2001;17;153C. Presented to the Canadian Cardiovascular Congress 2001, (Halifax).

31. *Beck C, Penrod J, Gyorkos TW, Shapiro S, Pilote L. An application of instrumental variable methodology in

cardiovascular outcomes research to reduce confounding bias. Am J Epidemiol 2001;153:S81. Presented to the Congress of Epidemiology (Toronto).

32. Abrahamowicz M, Li G, Pilote L, Leffondré K, du Berger R, . Assessing the effects of longitudinal within-

subject changes in risk factors on coronary heart disease mortality. Am J Epidemiol 2001;153:S65. Presented to the Congress of Epidemiology (Toronto).

33. Eisenberg MJ, Pilote L, Blankenship J et al: Aggressive Diagnosis of Restenosis: results from the ADORE

Trial. J Am Coll Cardiol 2001 (Late-Breaking Clinical Trials Session) 38:599. Presented to the American College of Cardiology (Orlando).

34. *Beck C, Penrod J, Gyorkos TW, Shapiro SH, Pilote L. Does aggressive care following acute myocardial

infarction reduce mortality? Analysis with instrumental variables to compare effectiveness in Canadian and United States patient populations. J Gen Inter Med 2001;16(Suppl 1):117. Presented to the Society of Internal Medicine (San Diego) and at the Canadian Society of Internal Medicine (Banff).

35. Pilote L, Lauzon C, Huynh T, Dion D, Roux R, Racine N, Carignan S, Diodati JG, Charbonneau F, Lévesque C,

Pouliot J, Joseph L, Eisenberg MJ. A prospective cohort study of quality of life after acute myocardial infarction at sites with and without coronary angiography. J Am Coll Cardiol 2001;37(Suppl A):491A. Presented to the American College of Cardiology (Orlando).

36. Pilote L, Joseph L, Bélisle P, Penrod J. Universal health insurance coverage does not eliminate inequities in

access to cardiac procedures after acute myocardial infarction. J Am Coll Cardiol 2001;37(Suppl A):497A. Presented to the American College of Cardiology (Orlando).

37. *Beck C, Joseph L, Eisenberg MJ, Huynh T, Diodati JG, Racine N, Charbonneau F, Lévesque C, Lauzon C,

Carignan S, Dion D, Roux R, Pouliot J, Pilote L. Predictors of quality of life 6 months and 1 year after acute

30

myocardial infarction. J Am Coll Cardiol 2001;37(Suppl A):491A Presented to the American College of Cardiology (Orlando).

38. Eisenberg MJ, Cugno S, Puri R, Blankenship J, Huynh T, Starling M, Pilote L. Routine functional testing

following percutaneous coronary intervention leads to increased clinical events in high-risk patients: results from the ADORE trial. Circulation 2002;106:II-437.

39. Eisenberg MJ, Azoulay A, Filion KB, Haider S, Pilote L. Outcomes and cost of coronary artery bypass graft

surgery in the United States and Canada. Circulation 2002;106:II-757. 40. *Karp I, Abrahamowicz M, Pilote L. Comparison of predictive ability of baseline versus updated risk factor

values. 4th Scientific Forum on Quality of Care and Outcomes Research In CVD and Stroke, Washington, DC, October 12-14, 2002. Travel Fellowship Award.

41. Abrahamowicz M, Esdaile J, Fortin PR, Neville C, du Berger R, Leffondré K, Pilote L, Karp I. Longitudinal

analyses of changes in cardiovascular risk factors in systemic lupus erythematosus. American College of Rheumatology, New Orleans, Louisiana, United States, October 25-29, 2002

42. *Hudson M, Rahme E, Pilote L, Baron M. Anti-inflammatory drugs are associated with a decreased risk of

recurrent acute myocardial infarction in patients on aspirin. Arthritis Rheum 2002;46(suppl):S617. Presented at the American College of Rheumatology Annual Scientific Meetings (New Orleans).

43. Cugno S, Eisenberg MJ, Huynh T, Blankenship J, Sedlis S, Starling M, Pilote L: Routine functional testing in

patients with diabetes mellitus: Results from the ADORE Trial. AHA (Asia-Pacific) 2002. 44. Cugno S, Eisenberg MJ, Blakenship J, Starling M, Sedlis S, Smilovitch M, Pilote L: Routine functional testing

in patients with low left ventricular ejection fraction: Results from the ADORE Trial. AHA (Asia-Pacific) 2002. 45. Pilote L, Simpson E, Beck CA, Lauzon C, Eisenberg MJ, for the Quality of Life After Acute Myocardial

Infarction (QOLAMI) Investigators. Diabetes and quality of life after acute myocardial infarction. Can J Cardiol 2002;18:234B. Canadian Cardiovascular Society, Edmonton, October 30, 2002.

46. *Essebag V, Hadjis T, Pilote L. Amiodarone and the risk of pacemaker insertion. Circulation

2002;106(Suppl):II-546. Presented at the American Heart Association Scientific Sessions (Chicago) and at the Canadian Cardiovascular Society (Edmonton).

47. *Rodriques E, Rahme E, Eisenberg MJ, Pilote L. Do ACE inhibitors exert a class effect on mortality after acute

myocardial infarction? International Society of Pharmacoepidemiology. Pharmacoepidemiology and Drug Safety 2002;11:S0-S0.

48. Filion KB, Pilote L, Haider S, Eisenberg MJ. Perioperative myocardial ischemic complicatioins following

abdominal aortic aneurysm repair lead to substantially increased in-hospital costs. J Am Coll Cardiol 2003;41(Suppl A):236A.

49. Rahme E, Kong SX, Watson DJ, Toubouti Y, Pilote L, LeLorier J. Association between rofecoxib

diclofenac/Ibuprofen and hospitalization for acute myocardial infarction: baseline patient characteristics. Arthritis and Rheumatism 2003;48(Suppl 9):S398.

50. Zhou Z, Richard H, Rahme E, Pilote L. A population-based study of benefit of statins in elderly AMI patients –

evidence of a class effect? Canadian Journal of Cardiology 2003;(19):244A.

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51. Buresly K, Pilote L, Eisenberg MJ, Zhang X. Bleeding complications from combinations of aspirin, warfarin, and thienopyridine derivatives in elderly patients following myocardial infarction. J Am Coll Cardiol 2003;41(Suppl A):154A. Presented at the 52nd Annual Scientific Session (Chicago).

52. Puri R, Eisenberg MJ, Pilote L, Blankenship J, Cugno S, Huynh T. Better functional status among U.S. than

non-U.S. patients after percutaneous coronary intervention: an effect of medical care? J Am Coll Cardiol 2003;41(Suppl A):521A. Presented at the 52nd Annual Scientific Session (Chicago).

53. Okrainec K, Eisenberg MJ, Pilote L. Physician-prescribing patterns among patients undergoing coronary artery

bypass graft surgery: results from the ROSETTA-CABG registry. J Am Coll Cardiol 2003;41(Suppl A):352A. Presented at the 52nd Annual Scientific Session (Chicago).

54. Gioia LC, Filion KB, Haider S, Pilote L, Eisenberg MJ. Hospital readmissions following abdominal aortic

aneurysm repair. J Am Coll Cardiol 2003;41(Suppl A):236A. Presented at the 52nd Annual Scientific Session (Chicago).

55. Eisenberg MJ, Teng FF, Chaudhry M, Ortiz J, Pilote L. Improved functional status and quality of life after

invasive management of non-ST segment elevation acute myocardial infarction. J Am Coll Cardiol 2003;41(Suppl A):398A-398A. Presented at the 52nd Annual Scientific Session (Chicago).

56. Eisenberg MJ, Filion KB, Haider S, Pilote L. Institutional variations in surgical treatment costs in the United

States and Canada. J Am Coll Cardiol 2003;41(Suppl A):523A-524A. Presented at the 52nd Annual Scientific Session (Chicago).

57. Eisenberg MJ, Filion KB, Moreland A, Saynina O, Pilote L, TECH Investigators.International trends in the use

of primary percutaneous coronary intervention. J Am Coll Cardiol 2003;41(Suppl A):4A-5A. Presented at the 52nd Annual Scientific Session (Chicago).

58. Marelli AJ, Rhame E, Pilote L. Congenital heart disease: Prevalence rates in a population of 5,363,695 adults. J

Am Coll Cardiol 2003;41(Suppl A):490A. Presented at the 52nd Annual Scientific Session (Chicago).

59. Rahme E, Dasgupta K, Ghosn J, Pilote L, Hudson M. Selective cyclooxygene-2 (COX-2) inhibitors protect against breast cancer. ACR/ARHP Annual Scientific Meeting, Orlando, FL, October 26, 2003.

60. Filion KB, Pilote L, Haider S, Eisenberg MJ. Effect of age on in-hospital length of stay, mortality, and cost

among patients undergoing abdominal aortic aneurysm repair. Circulation 2004;110:III-370. American Heart Association 2004.

61. Filion KB, Pilote L, Haider S, Eisenberg MJ. Hospital charges versus true costs among patients undergoing

coronary artery bypass graft surgery. Exp Clin Cardiol 2004; 9:51. Young Investigators Forum 2004. 62. Filion KB, Violette P, Pilote L, Haider S, Eisenberg MJ. Cardiac medical therapy among patients undergoing

coronary artery bypass graft surgery: A Pilot Study. Exp Clin Cardiol 2004;9:51. Young Investigators Forum 2004.

63. Eisenberg MJ, Okrainec K, Wou K, Nguyen H, Duerr R, Fourchy D, Del Core M, Lader E, Huynh T, Pilote L.

Utility of routine functional testing after coronary artery bypass graft surgery: results from the ROSETTA-CABG study. J Am Coll Cardiol 2004;43(Suppl A):273A.

64. *Karp I, Abrahamowicz M, Esdaile J, Fortin P, Neville C, Du Berger R, Pilote L. Longitudinal trajectories of

conventional cardiovascular risk factors in female patients with systemic lupus erythematosus. 7th International Congress on SLE and Related Conditions, May 2004.

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65. *Zhou Z, Rhame E, Pilote L. .Are Statins Created Equal? – Evidence from Randomized Trials of Pravastatin, Simvastatin, and Atorvastatin for Cardiovascular Disease Prevention. Can J Cardiol 2004;20:121D. Canadian Cardiovascular Annual Congress. October 2004. Calgary, Canada.

66. Martineau PA, Filion KB, Huk O, Zukor D, Pilote L, Antoniou J, Eisenberg MJ. Impact of hospital volume on

cost of total hip arthroplasty in Canada. Canadian Orthopedic Association 2004. 67. *Zhou, Z, Rahme, E, Abrahamowicz, M, Tu, JV, Eisenberg, MJ, Humphries, K, Austin, PC, Pilote, L. Benefit

of Statins for Secondary Prevention in Elderly Patients After Acute Myocardial Infarction: An Evaluation of A Class Effect. Canadian Cardiology Congress. J Am Coll Cardiol 2004;43(Suppl A):446A.

68. Gitman M, Okrainec K, Nguyen H, Duerr R, Del Core M, Fourchy D, Huynh T, Lader E, Rogers RJ, Chaudry

MR, Pilote L, Eisenberg MJ. Impact of diabetes on twelve-month outcomes following coronary artery bypass graft surgery: results from the Routine Versus Selective Exercise Treadmill Testing After Coronary Artery Bypass Grafting (ROSETTA-CABG) Registry. J Am Coll Cardiol 2004;43(Supll A):268A.

69. Norris CM, Pilote L. Depression; The Gender Specific Consequence of Recovery in Women Following an

Acute Myocardial Infarction. Second International Conference on Women, Heart Disease and Stroke. Orlando, Florida, February 16-19, 2005. Am Heart Assoc.

70. Abrahamowicz M, Sylvestre M-P, Pilote L, Leffondré K. New method for handling residual confounding by

severity in observational studies. 26th Annual Conference of the International Society for Clinical Biostatistics (ISCB), Szeged, Hungary, August 24, 2005.

71. Morin S, Hudson M, Behlouli H, Pilote L. Incidence and outcomes of hip fractures in Quebec, Canada, 1992-

2002. ASBMR 27th Annual Meeting, September 23-27, 2005, Gaylord Opryland Resort and Convention Center, September 25, 2005, Nashville, Tennessee, USA.

72. Marelli AJ, Mackie AS, Ionescu-Ittu R, Rahme E, Pilote L. Congenital heart disease: Health care utilization in a

population of 26,978 adults. Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 22-26, 2005.

73. Rinfret S, Abrahamowicz M, Tu JV, Humphries K, Eisenberg MJ, Richard H, Austin PC, Pilote L. A population-based analysis of the class effect of beta-blockers in elderly patients after myocardial infarction. Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 22-26, 2005.

74. Hudson M, Rahme E, Richard H, Pilote L. The risk of congestive heart failure with non-steroidal anti-

inflammatory drugs and selective cyclooxygenase-2 inhibitors – A class effect? Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 22-26, 2005.

75. Beck CA, Pilote L, Tu J, Richard H. Administrative data feedback for effective cardiac treatment (AFFECT): A

cluster randomized trial. Oral presentation at the Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 22-26, 2005.

76. Huynh T, Harvey R, Nguyen M, Eisenberg M, Rinfret S, Schampaert E, Cantin B, Afilalo M, Kouz S, Haichin

R, Paradis G, Pilote L. Time delays in achieving reperfusion in Quebec during the year 2003: Results of the AMI Quebec study. Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 22-26, 2005.

77. Dasgupta K, O’Loughlin J, Paradis G, Chen S, Pilote L. Sex differences in systolic blood pressure during

adolescence. Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 22-26, 2005.

78. Hudson M, Rahme E, Behlouli H, Sheppard R, Pilote L. Sex differences in the effectiveness of angiotensin receptor blockers and angiotensin converting enzyme inhibitors in patients with congestive heart failure – A population study? Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 22-26, 2005.

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79. Hudson M, Behlouli H, Pilote L. Mortality rates in elderly patients with congestive heart failure who take

different angiotensin receptor blockers: A class effect? Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 22-26, 2005.

80. Shrier I, Platt R, Brophy J, Kakuma r, Pilote L, Oremus M, Boivin J-F, Steele R, Schachter H. Inclusion criteria

for systematic reviews: What is the most valid approach. XIII Cochrane Colloquium, Melbourne, October 23, 2005.

81. Hudson M, Rahme E, Richard H, Pilote L. The risk of congestive heart failure with non-steroidal anti-

inflammatory drugs and selective cyclooxygenase-2 inhibitors – A class effect? ACR/ARHP Annual Scientific Meeting 2005, San Diego, CA, November 12-17, 2005.

82. Abrahamowicz M, Fortin P, Pilote L, Neville C, du Berger R, Karp I, Leffondré K, Clarke A, Esdaile J. Current

corticosteroid use in an independent risk factor for cardiovascular morbidity in systemic lupus erythematosis. ACR/ARHP Annual Scientific Meeting, San Diego, California, USA, November 12-17, 2005.

83. Shrier I, Platt R, Brophy J, Kakuma R, Pilote L, Oremus M, Boivin J-F, Steele R, Schachter H. Discussion on

the validity of different inclusion criteria for systematic reviews. 4th Canadian Cochrane Symposium, Montreal, Quebec, December 3rd, 2005.

84. Morin S, Rahme E, Behlouli H, Tenenhouse A, Goltzman D, Pilote L. Effectiveness of antiresorptive therapy

for the prevention of recurrent hip fracture. Cinical and Investigative Medicine 2005; 29:319. 85. Balashov K, Feldman DE, Savard S, Houde S, Frenette M, Ducharme A, Giannetti N, Michel C, Pilote L.

Percent Predicted Value from reference equations for the six-minute walk test: A better indicator of severity of heart failure condition. Am Coll Cardiol, 55th Annual Scientific Session 2006, Atlanta, Georgia, USA, March 11-14, 2006.

86. Filion KB, Pilote L, Rahme E, Eisenberg MJ. The use and effectiveness of perioperative cardiac medical

therapy among patients undergoing coronary artery bypass graft surgery. Am Coll Cardiol, 55th Annual Scientific Session 2006, Atlanta, Georgia, USA, March 11-14, 2006.

87. Mackie AS, Pilote L, Ionescu-Ittu R, Rahme E, Marelli AJ. Healthcare resource utilization in adults with

congenital heart disease: A population-based study. Am Coll Cardiol, 55th Annual Scientific Session 2006, Atlanta, Georgia, USA, March 11-14, 2006.

88. Marelli AJ, Mackie AS, Ionescu-Ittu R, Rahme E, Pilote L. The changing age distribution of severe congenital

heart disease in the general population. Am Coll Cardiol, 55th Annual Scientific Session 2006, Atlanta, Georgia, USA, March 11-14, 2006.

89. *Karp I, Pilote L. Sex Differences in the Efficacy of Statins in Patients After Acute Myocardial Infarction. Am

Coll Cardiol, 55th Annual Scientific Session 2006, Atlanta, Georgia, USA, March 11-14, 2006.

90. Pilote L, Abrahamowicz M, Cox J, Eisenberg M, Ghali W, Hamet P, Humphries K, Kirkland S, Norris C, O’Loughlin J, Tu J, Poole J, Savard S, Tremblay J, et al. GENESIS: Gender and Sex Determinants of Cardiovascular Disease: From Bench to Beyond. The beginning of a Research Network. MUHC Research Institute Fifth Annual Research Day. Montreal, Quebec, May 8, 2006.

91. Marelli A, Therrien J, Mackie A, Ionescu-Ittu R, Pilote L. Planning for the future of adult congenital heart

disease patients: From numbers to guidelines. American Heart Association, Montreal, Quebec, October 2006.

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92. Karp I, Behlouli H, Rahme E, Pilote L. Dose-response analysis of ramipril and metoprolol in elderly congestive heart failure patients. American Heart Association, Montreal, Quebec, October 2006.

93. Doucet M, Pilote L. Rapidly growing invasive cardiac procedure utilization in elderly patients after myocardial

infarction: A population study. Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 21-25, 2006. (printed)

94. Thanassoulis G, Humphries KH, Tu JV, Chen S, Karp I, Pilote L. Effects of a restrictive vs. liberalized

provincial policy on access and utilization of angiotensin-receptor-blockers among CHF patients not receiving ACE-inhibitors. Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 21-25, 2006.

95. Thanassoulis G, Humphries KH, Tu JV, Chen S, Karp I, Pilote L. Provincial variations in prescribing practices

in CHF patients with COPD: A possible effect of provincial prescription policies. Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 21-25, 2006.

96. Thanassoulis G, Humphries KH, Tu JV, Chen S, Karp I, Pilote L. Effects of provincial variations in

prescription practices on heart failure outcomes. Canadian Cardiovascular Society (CCS), Montreal, Quebec, October 21-25, 2006.

97. Thanassoulis G, Humphries K, Tu JV, Chen SF, Pilote L. A restrictive prescription policy contributes to

underutilization of angiotensin-receptor-blockers among heart failure patients not receiving ACE-inhibitors. American Heart Association, Chicago, Illinois, USA, November 12-15, 2006.

98. Filion K, Pilote L, Joseph L, Paradis G, Rinfret S, Gervais A, O’Loughlin J, Yavin D. Smoking cessation

pharmacotherapy meta-analysis. Amerian Heart Association Meeting, Chicago, Illinois, USA, November 12-15, 2006.

99. Eisenberg MJ, Yavin D, Filion KB, Bélisle P, Joseph L, Gervais A, O’Loughlin J, Paradis G, Rinfret S, Pilote L.

A hierarchical bayesian meta-analysis of randomized controlled trials of smoking cessation pharmacotherapies. American Heart Association Meeting, Chicago, Illinois, USA, November 12-15, 2006.

100. Pilote L, Poole P. GENESIS (Gender and Sex Determinants of Cardiovascular Disease: From Bench to

Beyond): Conduct of an ICE Team. McGill Cardiovascular Research Day 2007. Montreal, Quebec, February 1, 2007.

101. Mottillo S, Filion KB, Gervais A, Joseph L, O'Loughlin J, Paradis G, Pihl R, Pilote L, Rinfret S, Tremblay M,

Eisenberg MJ. A Meta-Analysis of Smoking Cessation Behavioral Interventions. Am Coll Cardiol, 56th Annual Scientific Session 2007, New Orleans, Louisiana, USA, March 24-27, 2007. (poster)

102. Marelli AJ, Mackie AS, Ionescu-Ittu R, Rahme E, Pilote L. Changing Age Distribution of Death in Congenital

Heart Disease from 1988 to 2005: a Population Based Study. Am Coll Cardiol, 56th Annual Scientific Session 2007 New Orleans, Louisiana, USA, March 24-27, 2007. (poster)

103. Hamet P, Seda O, Gaudet D, Brunelle PL, Gurau A, Merlo E, Pilote L, Kotchen T, Cowley AW, Tremblay J.

Adjustment for sex and age may conceal significant sex-and-age-specific genomic determinants of physiological traits. American Society of Human Genetics Montreal, Quebec June 2007.

104. *Ionescu-Ittu R, Marelli AJ, Pilote L. Increase in Folic Acid intake in teh preconceptual Period Reduce Birth

Prevalence of Severe Congenital Heart Disease. American Heart Association Montreal, Quebec June 2007. Received the 2007 Outstanding Research Award in Pediatric Cardiology from the Council on Cardiovascular Disease in the Young.

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105. Dasgupta K, Joseph L, Pilote L, Chan C, Sigal R, Da Costa D, Strachan I, Chan D, Ross N. Walking is Associated with Neighbourhood Characteristics among Adults with Type 2 Diabetes. 2007 American Diabetes Association conference. Chicago, U.S.A. June 22-26, 2007.

106. Grandi S, Gervais A, Joseph L, O’Loughlin J, Paradis G, Pilote L, Rinfret S, Sarrafzadegan N, Sharma S,

Lauzon C, Ghannem H, Wightman H, Lutchmedial S, Picard J-P, Giannoccaro P, Huynh T, Diodati J, Grondin F, Klinke P, Wielgosz A, Abramson B, Eisenberg MJ. Smoking Cessation Following Acute Coronary Syndrome. American Heart Association Montreal, Quebec June 2007.

107. Melo M, Newman A, Behlouli H, Rinfret S, Jackevicious C, Tu J, Demers V, Johansen H, Humphries K, Cox

J, Kalavrouziotis D, Pilote L for the Canadian Cardiovascular Outcomes Research Team. Clopidogrel use post-stent in AMI patients in two Canadian provinces. Quebec City, Quebec August 19-22, 2007.

108. Karp I, Behlouli H, Lelorier J, Pilote L. Statins and Cancer Risks. Presentation as part of the ISPE Scientific

Program Committee. Quebec City, Quebec August 19-22, 2007. 109. Mackie A, Marelli A, Ionescu-Ittu R, Rahme E, Pilote L. Hospital Readmissions in children with congenital

Heart Disease: A population-based study. Presentation at the Canadian Cardiovascular Society (CCS) meeting in Quebec City, Quebec October 20-24, 2007.

110. Abenhaim HA, Mottillo S, Filion KB, Bélisle P, Gervais A, Joseph L, O’Loughlin J, Paradis G, Pihl R, Pilote L,

Rinfret S, Tremblay M, Eisenberg MJ. A Systematic Review and meta-Analysis of Smoking Cessation Behavioral Interventions in Pregnant Women. Poster presentation at the Society for Maternal-Fetal Medicine. Am J obst Gynecol

111. Baboushkin T, Grandi S, Kristian F, Gervais A, Joseph L, O’Loughlin J, Paradis G, Pilote L, Rinfret S,

Eisenberg M. Assessing Smoking Cessation in Clinical Trials: The Need for Both Self-Report and Biochemical Validation. Poster presentation at the 14th Annual Nicotine Symposium and the Society for Research on Nicotine and Tobacco Control Conference, Portland, Oregon, February 26-March 1st, 2008.

112. Wakil SM, Filion KB, Genest J, Joseph L, Pilote L, Poirier P, Rinfret S, Schiffrin E, Eisenberg MJ. A Meta-

Analysis of the Effect of Weight Loss Pharmacotherapies on Metabolic Outcomes. Accepted for poster presentation at the 57th Annual Scientific Session, American College of Cardiology, Chicago, March 29- April 1, 2008.

113. Loucks EB, Pilote L, Lynch JW, Fuhrer R, Murabito JM, Richard H, Benjamin EJ. Childhood socioeconomic

circumstances predict inflammatory markers in Framingham. American Heart Association, 47th Annual Conference on Cardiovascular Disease Epidemiology and Prevention. March, 2007. Circulation. In press.

114. Abourbih SR, Filion KB, Belisle P, Joseph P, Schiffrin EL, Rinfret S, Poirier P, Pilote L, Genest J, Eisenberg M.

Effect of Fibrates on Cardiovascular and Metabolic Outcomes: A Systematic Review and Meta-Analysis. 57th Annual Scientific Session, American College of Cardiology, Chicago, March 29- April 1, 2008.

115. Leung YW, Gravely-Witte S, Brual J, Macpherson A, Irvine J, Steward DE, Pilote L, Grace SL. Correlates of

Post traumatic Growth among Patients: Are There Any Sex Differences? 57th Annual Scientific Session, American College of Cardiology, Chicago, March 29- April 1, 2008.

116. Grandi S, Gervais A, Joseph L, O’Loughlin J, Gilles P, Pilote L, Rinfret S, Sarrafzadegan N, Sharma S, Lauzon

C, Gamra h, Wightman H, Lutchmedial S, Picard JP, Giannoccaro P, Huynh T, Diodati D, Grondin G, KlinkeP, Wielgosz A, Abramson B, Schwarz N, Eisenberg M. Smoking Cessation Following Acute Coronary Syndrome. 57th Annual Scientific Session, American College of Cardiology, Chicago, March 29- April 1, 2008.

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117. Morin S, Pilote L, Goltzman D, Rahme E, Behlouli H. Hip fracture incidence and mortality in Quebec - 1992 to 2002. Poster presentation at the ECTS Meeting to be held in Barcelona, May 24-28, 2008.

118. Dasgupta K, Joseph L, Pilote L, Manjoo P. Impact of walking on antropometrics and impact of anthropometrics

on glycemic control among men and women with type 2 diabetes. Poster presentation at the American Diabetes Association’s 68th Scientific Sessions, San Francisco, CA, June 6-10, 2008

119. Leung, Y.W., Gravely-Witte, S., Brual, J., Macpherson, A., Irvine, J., Stewart D.E., Pilote, L. & Grace, S.L.

(March, 2008). Correlates of Posttraumatic Growth among Cardiac Patients: Are there any Sex Differences? Journal of the American College of Cardiology, 51, 10 (Supplement A), A269.

120. Manjoo P, Joseph L, Pilote L, Dasgupta K. Waist-to-hip associated with A1C in type 2 diabetes. CDA/CSEM

Professional Conference, October 15-18, 2008.

121. Jackevicius CA; Tu J; Demers V; Melo M; Cox J; Rinfret S; Kalavrouziotis D; Johansen H; Behlouli H; Newman A; Pilote L.Cardiovascular Outcomes with Removal of Clopidogrel Prior Authorization in Patients Receiving Coronary Stents Post-myocardial Infarction. Canadian Cardiovascular Society (CCS) Toronto, ON, October 25-29, 2008. Circulation. 2008;118:S_1106-S_1107.

122. Thanassoulis G, Brophy JM, Richard H, Behlouli H, Pilote L. The Effect of and Allopuinol Use on Heart

Failure Outcomes. Canadian Cardiovascular Society (CCS) Toronto, ON, October 25-29, 2008. Poster presentation

123. Rabi DM, Lewin AM, Dasgupta K, Simpson SH , Pilote L, Ghali WA, Johnson JA. Cardioprotective

Medication Utilization Stratified by Sex and Cardiovascular Disease Status, Among Those with Recent Onset Diabetes. Canadian Cardiovascular Society (CCS) Toronto, ON, October 25-29, 2008. Oral presentation

124. Shames S, Feldman D, Behlouli H, Giannetti N, Ducharme A, Michel C, Sheppard R, Grondin FR, Frenette M,

LeBlanc M, Pilote L. Sex Differences in Quality of Life in Multidisciplinary Congestive Heart Failure Clinics. . Canadian Cardiovascular Society (CCS) Toronto, ON, October 25-29, 2008

125. Akhtari S, Daskalopoulou S, Pilote L. Sex Differences in Premature Acute Coronary Syndrome. Canadian

Cardiovascular Society (CCS) Toronto, ON, October 25-29, 2008 126. Vallée M, Mayo N, Behlouli H, Pilote L. The Incidence and Prevalence of Hypertension in the Province of

Québec. Canadian Cardiovascular Society (CCS) Toronto, ON, October 25-29, 2008

127. Bottega N, Zhang S, Ionescu-Ittu R, Therrien J, Martucci G, Pilote L, Marelli A. Rising Numbers of Pregnancies and Offspring in Women With Congenital Heart Disease: A Population-Based Study. American Heart Association, Scientific Sessions November 8-12, 2008. New Orleans

128. Jackevicius CA; Tu J; Demers V; Melo M; Cox J; Rinfret S; Kalavrouziotis D; Johansen H; Behlouli H;

Newman A; Pilote L.Cardiovascular Outcomes with Removal of Clopidogrel Prior Authorization in Patients Receiving Coronary Stents Post-myocardial Infarction. American Heart Association, Scientific Sessions November 8-12, 2008. New Orleans

129. Bernier M, Marelli A, Bouchardy J, Bottega N, Martucci G, Pilote L, Therrien J. Atrial Arrhythmias in Adults

with Congenital Heart Disease: Right Versus Left, Does it Matter? American Heart Association

130. Mottillo S, Filion K, Bélisle P, Joseph L, Genest J, Pilote L, Poirier P, Rinfret S, Schiffrin E, Eisenberg M. Increased cardiovascular risk in patients with the metabolic syndrome: a systematic review and meta-analysis. American Heart Association

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131. Khan N, Quan H, Palepu A, McAlister F, Hill M, Pilote L. Differences in Stroke Care and Outcomes among South Asian, Asian/Pacific Islander and European Patients: Results from the Registry of the Canadian Stroke Network. American heart Association International Stroke Conference February 18-20, 2009.

132. Racco C, Barbosa N, Pilote L, Sternberg L, Abramson B, Melvin K, Grace SL. (2009). Female heart patient's

perceptions of innovative cardiac rehabilitation models: Home-based programs. Women's Health 2009: the 17th Annual Congress. Williamsburg, VA. March.

133. Bernier M, Marelli A, Bouchardy J, Bottega N, Martucci G, Pilote L, Therrien J. Atrial Arrhythmias in Adults with Congenital Heart Disease: Right Versus Left, Does it Matter? ACC Annual Meeting 58th Annual Scientific Session, March 29-31 Orlando, FL.

134. Lowe B, Therrien J, Bottega N, Bouchardy J, Guo Lm Ionesscu-Ittu R, Pilote L, Martucci G, Marelli AJ.

Pulmonary hypertension compounds Hospitalization and Mortality in Adults with Congenital Heart Disease: A population based study. ACC Annual Meeting 58th Annual Scientific Session, March 29-31 Orlando, FL.

135. Behlouli H, Feldman D, Ducharme A, Frenette M, Giannetti N, Grondin F, Michel C, Sheppard R, Pilote L.

Identifying relative cut-off scores with neural networks for interpretation of the Minnesota living with heart failure questionnaire. 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, September 2-6, 2009, Minneapolis, Minnesota, USA.

136. Manjoo P, Joseph L, Pilote L, Dasgupta K. Waist to hip mediates inverse association of walking with A1C but

not of walking with blood pressure among women with type 2 diabetes. International Diabetes Federation 20th World Diabetes Congress, Montreal, Quebec, October 18-22, 2009. (Accepted)

137. Dasgupta K, Joseph L, Da Costa D, Pilote L, Christopoulos S, Gougeon R. Pilot study demonstrates promise for

dietary counseling-cooking lesson intervention in type 2 diabetes. International Diabetes Federation 20th World Diabetes Congress, Montreal, Quebec, October 18-22, 2009. (Accepted)

138. Pagé M, Doucet M, Belhouli H, Eisenberg MJ, Pilote L. Coronary artery bypass grafting after acute myocardial

infarction in the elderly: 1996-2006 trends of use and long-term outcomes in the province of Quebec. Canadian Cardiovascular Congress 2009 Edmonton, Alberta October 24-28 (Accepted)

139. Guertin J, Pilote L et al. Potential cost savings with restrictive access to angiotensin-receptor blockers in

Quebec; a decision analysis model. Canadian Cardiovascular Congress 2009 Edmonton, Alberta October 24-28 (Accepted)

140. Feldman, Frenette, Giannetti, Grondin, Huynh, Michel, Montigny, Sheppard, Lepage, DesLauriers, Behlouli,

Pilote. Access to heart failure (HF) care post emergency visit: do we meet established benchmarks? Canadian Cardiovascular Congress 2009 Edmonton, Alberta October 24-28 (Accepted)

141. Jackevicius C, Tom A, Essebag V, Eisenberg M, Rahme E, Tu J., Humphries K, Behlouli H, Richard H, Pilote

L, Pulmonary Toxicity Associated With Amiodarone: Population-Level Incidence and Risk Factors. American Heart Association AHA Scientific Sessions November 2009 in Orlando, Florida. (Accepted)

142. Thanassoulis G, Brophy J, Richard H, Pilote L. The Effect of Gout and Allopurinol Use on Heart Failure

Outcomes. American Heart Association AHA Scientific Sessions November 2009 in Orlando, Florida. (Accepted)

143. Guertin JR, Jackevicius CA, Cox J, Humphries K, Johansen H, Pilote L, So D, Tu JV, Wijeysundera H, Rinfret

S. Potential Cost Savings With Restrictive Access to Angiotensin-Receptor Blockers in Canada: A Decision Analysis Model. American Heart Association AHA Scientific Sessions November 2009 in Orlando, Florida. (Accepted)

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144. Page M, Doucet M, Eisenberg M, Belhouli H, Richard H, Pilote L. Temporal Trends in Use of Coronary Artery Bypass Grafting and Outcomes in Octogenarians With Acute Myocardial Infarction. American Heart Association AHA Scientific Sessions November 2009 in Orlando, Florida. (Accepted)

145. Afilalo J, Therrien J, Pilote L, Ionescu-Ittu R, Martucci G, Marelli A. Geriatric Congenital Heart Disease:

Trends in Prevalence and Predictors of Mortality. American Heart Association AHA Scientific Sessions November 2009 in Orlando, Florida. (Accepted)