lotus pharmaceutical · 2018. 8. 15. · page i 5 lotus pharmaceutical is an apac generics leader 1...
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LOTUS PHARMACEUTICALBUILDING A REGIONAL LEADER
August 2018
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Safe Harbor Statement
Except for historical information contained herein, the matters set forth in this presentation are forward
looking statements that are subject to risks and uncertainties that could cause actual results to differ
materially. These forward looking statements are not based on historical facts but rather on
management’s expectations regarding future growth, results of operations, performance, future capital
and other expenditures, competitive advantages, business prospects and opportunities. Statements in
this presentation about our future plans and intentions, results, level of activities, performance, goals or
achievements or other future events constitute forward looking statements. Wherever possible, words
such as “anticipate”, “believe”, “expect”, “may”, “could”, “will”, “potential”, “intend”, “estimate”, “should”,
“plan”, “predict”, or the negative or other variations of statements reflect management’s current beliefs
and assumptions and are based on the information currently available to our management. Investors
are cautioned not to place undue reliance on these forward looking statements, which are made
as of the date of this presentation and we assume no obligation to update or revise any forward
looking statements.
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Table of Contents
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Company Overview
2Q 2018 Financial/Operational Results
Profitable Growth Strategy
Key Assets Update
Page I 4Page I 4
COMPANY OVERVIEW
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LOTUS PHARMACEUTICAL IS AN APAC GENERICS LEADER
1
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Founded in 1966Lotus Pharmaceutical is among Taiwan’s largest specialty-generic drug
developers and one of the early movers to export to the US market since 2011
Its portfolio includes CNS, CVS, oncology, women health, anti-obesity, respiratory
and pain relief in forms of tablet, capsule and soft gel capsule
The rising generic leader in APACLotus is positioned as a regional platform for Alvogen Group (63.4% holding in
Lotus) since Aug 2014 through a reverse merger, and leverages Alvogen Group’s
cross-border reach to scale up
The current operation scope of Lotus spans across Lotus Taiwan’s domestic
business, Alvogen Korea’s domestic business, Alvogen Pharma India’s CRO
business, and export businesses
Capital market milestone
Lotus Pharmaceutical (1795. TWO) has been listed on Taipei Stock Exchange
since 2010 and became a Taiwan Market Biotechnology and Medical Care Index
stock in July 2017
Extraordinary quality management Lotus’ R&D and manufacturing facilities in Nantou is the only one in Asia that’s
approved by US FDA, EU EMA, Japan PMDA and TFDA PIC/S
1
2
3
4
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70+ Generic products in pipeline
2 Biosimilar products in pipeline (mab’s)
8 MAs in the US; 26 MAs in Europe;
9 MAs in Japan; 1 MA in China
A FAST GROWING GENERICS & SPECIALTY PHARMACEUTICAL POWERHOUSE
Lotus facts
Page I 6
1000+ Employees
3 Manufacturing and R&D Centers
300+ Marketed products
150+ Submissions since 2012
11%
19%
23%
47%
Lotus Taiwan EmployeesTotal: 386
G&A
R&D
S&M
Plant
10%
8%
48%
34%
Alvogen Korea Employees Total: 536
G&A
R&D
S&M
Plant
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2015-2016
POST MERGERINTEGRATIONPHASE
2017-2018
INITIALGROWTHPHASE
2019~
EXPLOSIVEGROWTHPHASE
LOTUS SEES TANGIBLE PROGRESS TOWARD TRANSFORMATION
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• Upgrade Nantou plant
• Change management team
• Reshape Portfolio and
pipeline
• Adjust sales and marketing
strategy
• Resolve legacy issues
• Build key franchises in each
APAC market
• Focus on specialty driven
markets
• Continue to increase
operational efficiency
• US and EU export revenues to
significantly grow
• High value products and
economies of scale to drive up
gross margin
• Strengthen balance sheet
• Invest in key franchises and
become category leader
• More aggressive CAPEX plan
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WE STABILIZED IN 2017 AND HAS LAID A SOLID GROWTH GROUND
8
-1000
0
1000
2000
3000
4000
5000
6000
7000
2014 2015 2016 2017
4 Year Trend (NT$mn)
Rev. Gross Profit Operating Profit
50%
59% 56% 48%
-19%
8% 4% 8%
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1H 2018 FINANCIAL/OPERATIONAL
RESULTS
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GM RECOVERED, ASSET SHUFFLING AND WIP BENEFIT PLAN HURT NET MARGIN
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Unit: NT$000 2Q 2018 % 2Q 2017 % 1Q 2018 % QoQ YoY
REVENUE $1,635,282 100 $1,577,430 100 $1,489,784 100 9.77% 3.67%
COGS 852,397 52 829,640 53 806,504 54 5.69% 2.74%
GROSS PROFIT 782,885 48 747,790 47 683,280 46 14.58% 4.69%
OPEX
S&M 444,393 27 350,393 22 360,328 25 23.33% 26.83%
G&A 165,305 10 160,021 10 165,889 11 -0.35% 3.30%
R&D 73,185 5 69,653 5 88,062 6 -16.89% 5.07%
Total OPEX 682,883 42 580,067 37 614,279 42 11.17% 17.72%
INCOME FROM OPERATIONS 100,002 6 167,723 11 69,001 4 44.93% -40.38%
NON-OP INCOME & EXP
Finance costs -81,694 -5 -63,341 -4 -70,778 -5 15.42% 28.97%
Others -27,453 -2 1,774 0 20,610 2 -233.2% -1647.52%
Total non-op expenses, net -109,147 -7 -61,567 -4 -50,168 -3 117.56% 77.28%
INCOME BEFORE TAX -9,145 -1 106,156 7 18,833 1 NA NA
INCOME TAX EXPENSE
(BENEFIT)39,652 -2 48,632 -3 -6,149 1 NA NA
NET ERANINGS (LOSS) -48,797 -3 57,524 4 24,982 1 NA NA
EPS -$0.23 $0.15 $0.07 NA NA
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ADJUSTED NET PROFIT WAS ACTUALLY BETTER THAN 2Q 2017
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• GP WIP KR RPP impact from operators (–NT$ 17mn)
• OPEX
1. Higher S&M from WIP KR RPP impact (-NT$ 63mn)
2. Higher R&D from WIP KR RPP impact (-NT$ 4mn)
3. Higher G&A from WIP KR RPP impact (-NT$ 7mn)
• Non-Op early debt repayment amortization fee (- NT$ 21mn) in Korea
Adjustment Items:
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• GP + NT$ 52mn from higher sales and product mix
• OPEX:
1. Higher S&M from increased marketing in Taiwan for Aclasta
2. Disciplined R&D spending irrespective of growing pipeline
3. Lower actual G&A from decreased spending base
STRONG OPERATIONAL RESULTS FROM HIGH SEASON AND REDUCED SPENDING
NT$mn
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ON TRACK OF BUILDING KEY FRANCHISES IN EACH APAC MARKET
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INN Indication YTD (NT$mn) YoY (%) Remarks
1 Goserelin (Zoladex) Breast cancer 乳癌 274.4 +6%Exclusive marketing alliance with
AstraZeneca KR; launched Oct’16
2 Rosuvastatin/EzetimibeCardiovascular
降血脂與膽固醇261.0 +106% Dosage improved to 1/day
3 Sarpogrelate Anticoagulant 抗凝血 255.8 +31% FDC; launched in 1Q16
4 Calcium Polystyrene Sulfonate Nephrology 腎臟病 159.6 -8%
5 Seroquel (Quetiapine) Schizophrenia 精神分裂症 143.2 -7%Exclusive marketing alliance with
AstraZeneca KR; launched Oct’15
6 Desogestrel/EE (Mercilon)Oral contraceptive
口服避孕藥132.6 +5%
Acquired from Bayer; launched in
May’16
7 Bicalutamide Prostate cancer 攝護腺癌 104.3 -5%Exclusive marketing alliance with
AstraZeneca KR; launched Oct’16
8 Phentermine Anti-obesity 減肥 101.0 -20%
9 Anastrozole (Arimidex) Oncology 癌症 95.5 +2%Exclusive marketing alliance with
AstraZeneca KR; launched 4Q’16
10 Phendimentrazine Anti-obesity 抑制食慾 81.2 -15%
11 Zoledronic Acid (Aclasta) Osteoporosis 骨質疏鬆症 81.1 +12%Acquired from Novartis; launched
Apr’17; TW product
12 Orlistat Anti-obesity 減肥 70.8 -4%
13 Methylprednisolone Anti-infection 抗感染 46.7 +42% Tender driven
14 Trazodone Anti-depression 憂鬱症 40.9 +49% CN product
15 Benzonatate Oral Cough Suppressant 止咳 38.1 +30% TW product
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FRANCHISE SOLIDIFICATION CONTINUES TO HELP P&L AND CF
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Key Performance Indicator I: More diversified geographically
We will keep improving commercial performance by solidifying franchise leadership to maximize
revenue growth and cash flow
2016
2017
1H2018
85.4%
80.6%
82.7%
7.8%
10.3%
11.5%
2.6%
6.5%
2.9%
4.0%
2.6%
2.9%
Korea Taiwan Export (milestone + shipment) India
Key Performance Indicator II: Back on cash-generating track
Unit: NT$mn
13%
26%
21% 21%
12%
7%
14%
0%
5%
10%
15%
20%
25%
30%
0
100
200
300
400
500
600
700
800
1H15 2H15 1H16 2H16 1H17 2H17 1H18
Net cash generated from operation
of total sales
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LATE PHASE
Vinorelbine softgel capsules for Europe
LP149 ROW
SUBMISSIONS
Methotrexate for US
Gefitinib for Europe
Lenalidomide for US and ROW
LAUNCHESTemozolomide for US, Europe and APAC
Levetiracetam ER & IR for US
Calcium Acetate for US
LAUNCH PREPERATIONS
Norethisterone/Ethinylestradiol LD for JP
TS-1 for KR
INCREASING PRESENCE IN FIRST WAVE FILING SUGGESTS STRONG R&D POWER
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2017 Deliverables
6 submissions for US and Europe markets in 2017
15+ # total active R&D projects
~85% % of R&D projects launching between 2018 – 2021
Acarbose for China
2018 Progress
LP173 for Europe
Levonorgestrel (US), Paricalcitol (US), Lenalidomide
(EU), Gefitinib (EU), Vinorelbine (EU)
LP149 for US
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PROFITABLE GROWTH
IN A RAPIDLY CHANGING ENVIRONMENT, WHAT MAKES US DIFFERENT 17
ENVIRONMENT
• Shifting demographics
• Political and regulatory
volatility
• High impact therapies for
high demand patients
RESOURCES WE EMPLOY
• Strong collaborations and
partnerships
• Plant and equipment
• Talented employees and
Alvogen culture
HOW WE STAND OUT
• Commitment to internal and
external innovation
• Strong franchises that
enable leadership
• Relentless focus on unmet
medical needs
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OUR GOAL FROM NOW TILL 2020– GROWTH, MARKET SHARE, REINVESTMENT
Back to Basics
Value Differentiation
Geared Up For The Future
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Profitable
Growth
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BACK TO BASICS
• Strong Portfolio
• Best Service
• Best Quality
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ONLY VERY FEW SELECTED CATEGORIES WILL GROW, AND WE ARE THERE
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As a fast follower, what does innovators’ trend tell us?
• Oncology drugs are dominating US approvals
• Small molecule oral solid dosage is the most brutal market now
• Small volume, high ASP is a must-play for pharma
24
8
2
6
8
10
11
9
19
59
16
9
14
18
13
13
10
16
Cancer
Diabetes
Respiratory
Infections viral
Other infections
Cardiovascular
Genetic
Immunology
CNS/Pain
2012-2017 2007-2011
‘17 TAM +21% YoY
US FDA new drug approval trend
Therapeutic Area 2016-2021 CAGR
Oncology 9-12%
Antidiabetics (CVS) 8-11%
Autoimmune Diseases
11-14%
Pain (CNS) 2-5%
Cardiovascular 0-3%
Mental Health (CNS) 1-2%
IMS global medicines outlook
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BEST QUALITY MAKES US THE MOST PREFERRED PARTNER OF OUR CUSTOMERS
Lotus quality record
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Korea – Gongju Plant Korea – Hyangnam Plant Taiwan – Nantou Plant
Products
• Tablets
• Coated tablets
• Hard capsules
• Powders, granules
• Tablets
• Coated tablets
• Hard capsules
• Powders, granules
• Tablets
• Coated tablets
• Softgel capsules
• Hard capsules
Capacity• Max capacity at 500mn
units of tablets
• Max capacity at 800mn
units of tablets
• Max capacity at 1.5bn
units of tablets
Accreditation • KGMP compliant • KGMP compliant
• US FDA, EU EMA, Japan
PMDA & TFDA PIC/S
approved
• Planning for China CFDA
inspection
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WE CAN NOT AFFORD TO GO AFTER GENERAL GENERICS ANYMORE
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2016A to 2020F therapeutic area revenue breakdown
18%
19%
9%16%
8%
30%
2017A
What is our portfolio strategy?
• Complex products
• High-barrier oncology products
• OTC and lifestyle products
• Local/regional partnerships and big pharma tail-end brands
15%
24%
10%16%
8%
27% Anti-obesity
CVS
CNS
Oncology
Women health
Others
1H 2018
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LOTUS PHARMACEUTICAL PROVIDES BEST SERVICE IN EVERY ASPECT
1
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Growing key markets sales team
70 in-house sales in Taiwan and 299 in-house sales in Korea, covering drug
stores, clinics, general and community hospitals
The best R&D partner
Partner with new drug companies from formulation development, phase I, or
clinical trial, providing critical CDMO or R&D services to new oncology drugs
companies targeting advanced markets such as US, EU and JP
Achieving vertical integration through CRO capabilities in India
Norwich Clinical Service provides biostudy, clinical and pharmacovigilance
services to Lotus & Alvogen Group and 3rd party customers, and holds an
oncology center in Bangalore, India
1
2
3
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VALUE DIFFERENTIATION
• Short Time to Market
• High Value Pipeline
• Leader in Special Dosage
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TIME TO MARKET IS ESSENTIAL AS MARKET SENTIMENT CHANGES
FDA is pro-active on
• Guidance on complex generics
• A basket of products without generics
• Prioritize FTM generics
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Increased competitions amid generics market, yet FTM is always favored
Source: FDA
Page I 26
Generic Name Indication
IMS
market size
(US$mn)
Formulation BE & CT Submission Approval
1Budesonide
ERGI 結腸潰瘍 US: 200 2019
2Buprenorphine/
Naloxone
Addiction
戒毒US: 2,000
4Q2018 –
1Q2019
3 MethotrexateChemo
癌症US: 340 2H2019
4 Gefitinib
Non-small-cell
lung cancer;
Inhibitor
非小細胞肺癌
Global: 375 2H2018
5 LenalidomideMultiple
Myeloma
血癌
Global:
9,700
ROW Approved
US 2020 - 2021
6 VinorelbineBreast cancer;
Chemo
乳癌EU: 130 2019
7 LP650GIST; inhibitor腸胃道間質腫瘤
EU & APAC:
6092020
8 LP149 ROWWomen health;
女性保健EU& APAC:
1102019
THE EMERGING NON-INDIAN PHARMA WITH FIRST WAVE PURSUIT GLOBALLY
To be launched in 2018 - 2021
NO BE
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PIV; non-infringement, CRL
PIV; non-infringement
PIV; sued in US; US technical review done
CRL
Focusing high value innovation for patients and customers
NO BE
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Generic
NameIndication
IMS
market size
(US$mn)
Formulation BE & CT Submission Approval
9 LP173
Late stage
onco for soft
tissues
sarcoma +
renal cell
carcinoma
腎癌、上皮細胞癌、軟組織
肉瘤(皆非一線)
Global: 792 2021
10 LP337
Late stage
hepatocellular
carcinoma,
renal cell
carcinoma,
thyroid
carcinoma
晚期肝細胞癌、晚期腎癌、分化型甲狀腺癌(皆非一線)
EU & APAC:
4702022
11 LP149 USWomen health;
女性保健FTF 2023
To be launched in 2021 - 2024
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200mg
400mg
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Generic Name Indication
IMS
Market Size
(US$mn)
Formulation BE & CT Submission Approval
1 AK-R214 (SR)Smoking Cessation
戒菸37
2Bazedoxifene
HCL (FDC)
Osteoporosis
骨質疏鬆18
3Bazedoxifene
(FTF)
Osteoporosis
骨質疏鬆8
4AK-R309
(FTF)
OAB
膀胱過動症24
THE LEADING SPECIALTY IMD DEVELOPER IN KOREA CONTINUES TO AIM HIGH
To be launched in 2018 - 2020
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IMD in Korea is similar to US 505b2 filing path with much condensed development and regulatory time
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LOTUS PHARMACEUTICAL IS THE REGIONAL LEADER IN SPECIAL DOSAGE
Soft Gel Manufacturing
• Safety, efficacy, bioavailability and solubility issues dominated
as the most significant factors in developing drug formulations
• According to BCS classification, ~70% of new chemical
entities (NCE) are class 2 or 4
• Lotus is the regional expert in delivering low-dose cytotoxic
and potent APIs as it can ensure dose uniformity, which is a
challenge with traditional tablet manufacturing and powder
capsulation processes
• Investment in dedicated manufacturing area starting 2009 and
current capacity at 500mn capsules / year
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SUMMARIZING “SPECIALTY” GENERICS OF OUR PIPELINE TO FIND VALUE 30
Molecule Exclusivity Status Forum & Success Rate How Not To Infringe
Orphan Drug: 7Y Delaware Seek IPR invalidation
Average NCE: 3Y New Jersey Polymorphic form redesign
Pediatric: N+6M Texas Composition redesign
Not NCE: None Label carve-out
• We focus on BCS Class 2 & 3 projects which
entail complicated in-vivo bioavailability and
bioequivalence studies
• We deploy softgel as a platform for BCS Class
2 & 4 projects
Small volume, High value Complex Molecules
Potential high market share from Complex IP Landscape
BY THE NUMBERS: WE BALANCE OUR RISK AND REWARD FOR STAKEHOLDERS
Page I 31
7%
63%
25%
5%
BCS Class 1
BCS Class 2
BCS Class 3
BCS Class 4
Complex Molecules
20%
20%
20%
20%
20%
No patent dispute, non505b2
Non NCE patentchallenge
NCE-1 PIV
Orphan drug exclusivity
505b2
Complex IP Landscape
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GEARED UP FOR THE FUTURE
• Emerging headway in the China storm
• Biosimilar Ready
• M&A Mode Always On
Page I 33Page I 33
9 molecules in discussion
WE ARE MAKING GOOD PROGRESS IN THIS MARKET WITH RISING QUALITY AWARENESS
01BE study data integrity, tax reform, two-invoice system, and recent vaccine and API
scandal have led to increasing portfolio acquisition activities in China
02We have set up BD and regulatory teams in China in 2017 and identified several
molecules for potential partnerships with Chinese CSO and pharmaceuticals
03Expect to launch ~2 significant products in China before 2020 in addition to at least 3
new submissions to take advantage of climate change
3+ partners in DD phase
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0.1 0.1 0.2 0.3 0.6 1.5
3.7
6.5
9.1
10.6 11.1
12.1 12.5 12.7
0.4 0.5 0.6 0.7 0.9
1.1
1.5
2.2
2.8
3.4
3.8
4.2
4.9 4.8
0.1 0.1 0.1 0.1 0.2
0.2
0.4
0.6
0.8
1.0
1.2
1.5
1.7 1.9
-
2.0
4.0
6.0
8.0
10.0
12.0
14.0
16.0
18.0
20.0
2012 2013 2014 2015 2016F 2017F 2018F 2019F 2020F 2021F 2022F 2023F 2024F 2025F
US Europe ROW
BIOSIMILAR READY
Lotus’ Biosimilar Play
Page I 34
• Biosimilars have reached an inflection point and we expect very rapid growth from
2017 onwards
• Secured APAC ex. Japan distribution rights of 2 biosimilar products of Alvotech,
Alvogen’s sister company
US$Bn
Source: PharmaCloud
Biosimilars reach 50% of
protein/big molecule market (~50%
of)US$33.7bn
Page I 35
M&A MODE ALWAYS ON
Pharmaceutical Market Size (US$bn)5yr CAGR (%)
2.1%
9.9%
11.6%
3.7%
9.2%
7.1%
7.3%
5.2%
13.9%
11.5%
9.2%
8.0%
7.6% 0.8
1.6
2.0
2.2
3.3
3.8
4.5
5.5
5.9
15.8
16.7
98.8
107.0
Singapore
Hong Kong
Bangladesh
Malaysia
Vietnam
Philippines
Thailand
Taiwan
Indonesia
Korea
India
China
Japan
Page I 35
Constantly looking for companies that complements our S&M strategy or portfolio
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KEY ASSETS UPDATE
Page I 37Page I 37
gSuboxone film(Buprenorphine/Naloxone)
Page I 38
BUP/NAL HAS ALL IT TAKES TO BE A TRANSFORMATIVE OPPORTUNITY
Page I 38
Clear Unmet
Medical Needs
Solution
Market
IPRegulatory
Medicaid Coverage
• Opioid addiction is increasing among Americans, with addiction to heroin, fentanyl, and
prescription painkillers such as Oxycodone, Codeine and Hydrocodone
• >40,000 Americans die every year because of OUD, growing at a CAGR of ~25% since 2015,
and that’s >300 times higher than flu deaths in the US
• Sales of Zubsolv and Bunavail proved that 505b2 failed to be the affordable alternative
Source: Medicaid and Kaiser Family Foundation
Page I 39
AND US GOVERNMENT IS FUNDING THIS TREATMENT
Buprenorphine Assisted Medication (BAT) leadership and Medicaid coverage are key
• Currently all states sponsor BAT, 66% sponsors Methadone, and >50% of states started to
include Naloxone in Medicaid program
• In 2016, average treatment payment is 77% out-of-pocket and 23% covered by Medicaid
• The House passed several bills regarding the Substance Use Disorder Prevention that Promotes
Opioid Recovery and Treatment (SUPPORT) Act, The Senate has approved the Helping to End
Addiction and Lessen (HEAL) Substance Use Disorders Act which will go live by 2H2018
Page I 39Source: Medicaid and Kaiser Family Foundation
Page I 40Page I 40
WE CLEARED MOST OF THE IP AND REGULATORY HURDLES
Only 2 generics shortlisted
Sept. ‘17: non-infringement of DRDBrand filed patent ‘454 (OB, composition patent, exp. 2029)Oct. ’17: Teva received FDA tentative approval but FTF 180 day exclusivity should be either lapsed or forfeited – TBC by FDA
2017
Suboxone film’s first year
FDA ok’d Indivior’s suboxone filmKey patents were ‘150 (exp. 2023), ‘514 (process patent, exp. 2024) and ‘497 (composition patent, exp. 2022)
2010
30 month stay expired, non-infringement on 3 patents, only 2 generics in the game
PIV filers sued
TEVA/Par, Mylan, DRD, Alvogen/Lotus, Sandoz
TEVA/Par and Mylan settled; Sandoz dropped
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ALVOGEN/LOTUS WILL BE AMONG 1ST WAVE TO ENJOY MARKET
TEVA and Par (FTF) enters market
2024
Mylan enters market
20232018
Mar. ’18: non-infringement of Alovgen/Lotus
Regulatory wise, Alvogen/Lotus responded to FDA questions in 2Q’17 and now expects to hear back by end of 2Q’18; FDA TAD for DRD should be similar
Brand filed patent ‘221 (OB, composition patent, exp. 2022) and patent ‘305 (filing OB listing)
“At risk” launch now possible
Up to 5 years of good margin and limited
competition
Page I 42Page I 42
Dr Reddy’s
(Current FTM)
Indivior
(innovator)
• New gen Sublocade
injection only achieved
1/10 of company estimates
• Sublocade is under REMS
control and can only be
prescribed at specialty
pharma and administered
in health centers Medicaid
works with
• This has led to a 27 to 60
days prescription journey,
36% dispense conversion
rate, and 27% YoY
increase in SG&A
IP & REGULATORY LANDSCAPE OF OUR COMPETITORS AND US:
WHAT HAPPENED SINCE JUNE
42
WHY ARE WE CONFIDENT?
• FDA approval in June
(along with partial strength
approval of Mylan’s); RDY
launch at risk = 4.7%
market share
• Indivior filed TRO and PI
was accepted then granted
in July; Dr. Reddy’s stay of
PI rejected; Federal Circuit
Court expedited Dr
Reddy’s PI appealing for
first week of Oct
• Indivior posted a bond of
US$1.27mn per day
Source: IR material of Indivior and Dr. Reddy’s
Page I 43Page I 43
gRevlimid (Lenalidomide)
Page I 44
LENALIDOMIDE: AN OPPORTUNITY TOO CRITICAL TO MISS
44
Lotus invested early in the development of this product, starting from its 1st gen Thalidomide
Lotus Nantou site is nicely equipped with cytotoxic manufacturing facilities for this product
Company will begin to benefit from early launches in APAC and CEE as early as 4Q 2018
Lotus is actively building IP case and REMS program for Lenalidomide in the, targeting first wave launch
Lotus received approval in Taiwan and EU within 12 months post-submission, and US FDA confirmed finalization of technical review in June 2018, signaling high quality of the dossier
Alvogen/Lotus targets to be the first wave generics globally
Page I 45
The foundation for vision 2020
FUEL FOR GROWTH
We will continue to set a new standard for our
industry outlined in a simple strategic model
BEST IN CLASS CUSTOMER SERVICE
HIGHEST QUALITY
HIGH OPERTIONAL EFFICIENCY
TARGETED PORTFOLIO
ONLY THE BEST PEOPLE
Page I 46Page I 46
APPENDIX
Page I 46
Page I 47
BALANCE SHEET ENDING JUNE 30TH 2018
Page I 47
Unit: NT$MN JUNE-30-2018 JUNE-30-2017CURRENT ASSETS
Cash & cash equivalents 2,022 13% 2,041 13%Notes and trade receivables, net 1,248 8% 1,148 8%Other receivables 7 0% 9 0%Other receivables from related parties 66 0% 10 0%Inventories 856 6% 985 6%Other current assets 115 1% 113 1%
4,314 28% 4,306 28%NON-CURRENT ASSETS
PP&E 1,864 12% 1,902 12%Goodwill & other intangibles 8,374 53% 8,458 54%Deferred tax assets 470 3% 433 3%Other non-current assets 613 4% 543 3%
11,321 72% 11,336 72%TOTAL ASSETS 15,635 100% 15,642 100%LIABILITIES & EQUITYCURRENT LIABILITIES
Loans & borrowings 310 2% 310 2%Notes and payables 783 5% 740 5%Other payables to related parties 114 1% 45 0%Current portion of long-term borrowings 704 5% 0 0%Other current liabilities 373 2% 577 4%
2,284 15% 1,672 11%NON-CURRENT LIABILITIES
LT Borrowings, net of current portion 2,257 14% 4,320 28%Loan payables to related parties - non-current 2,547 16% 822 5%Other non-current liabilities 996 6% 941 6%
5,800 37% 6,083 39%TOTAL LIABILITIES 8,084 52% 7,755 50%
EQUITY
Total equity attributable to owners of the company 7,133 45% 7,225 46%
Non-controlling interests 418 3% 661 4%Total equity 7,551 48% 7,886 50%
TOTAL LIABILITIES & EQUITY 15,635 100% 15,641 100%