Liver Pathology, CASE 2

• 53 year-old with chronic alcohol and drug abuse who has been in numerous rehabilitation facilities in the past now presents with abdominal pain after a 3-week alcoholic “binge.”

Identify the organDescribe the gross findings.Diagnosis?

The autopsy specimen of the liver reveals cirrhosis. The liver is discolored yellow-brown and has a nodular surface.

Identify the organDescribe the gross findings.Diagnosis?

Cirrhosis (alcoholic)The liver reveals fatty changes and nodularity.

Cirrhosis The surface of the liver is nodular.

Identify the organDescribe the gross findings.Diagnosis?

Cirrhosis (alcoholic)A cut section of the liver reveals micronodules and fatty change.

Describe the lower power histologic findings

Bands of fibrosis Producing pseudolobules

Describe the findings in this trichrome stain (stains collagen blue)

A - PseudolobuleB - Fibrosis

Mallory bodies

SteatosisFew neutrophilswith hepatocytenecrosis

Diagnosis?

• Acute alcoholic hepatitis superimposed on alcoholic cirrhosis.