literature sources in pharmacovigilance · • drug-induced ocular side effects(fraunfelder, 2002)...
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Literature Sources in Pharmacovigilance
Sten OlssonWHO-Uppsala Monitoring Centre
Sweden
Original journals
• Positive• Fast• Comprehensive information• Negative• Expensive• Low coverage• JAMA• Therapie• New Engl J of Med• Brit Med Journal• The Lancet
http://bmj.com/
Journals of special interest
• Pharmacoepidemiology & Drug Safety
• Drug Safety
• Risk & Safety in Medicine
• Adverse Drug Reactions and Toxicology
Reviews
Journals of special interest
Bibliographic titles review
• PositiveFast High coverage
• NegativeMinimal detail
Current Contents
Secondary review journals
• Positive- Quite fast- Some detail- High coverage
• Negative- Lack of detail- Difficult to search systematically- (Cost)
• Reactions Weekly
Expert annotated review
• Positive- Assessment of significance
- Easy access• Negative
- Lack of detail- Not completely up-to-date
• Meyler's Side Effects of Drugs
• Side Effects of Drugs Annual
• Adverse Drug Reaction Bulletin
• Prescrire
• Expert Opinion on Drug Safety
Reference books
Reference books
• Martindale – the extra Pharmacopoea
• Meyler’s Side Effects of Drugs
• Pharmacovigilance from A-Z
Reference books
Reference books
Textbooks
• Drug induced diseases– Textbook of Adverse Drug Reactions
(Davies, 1998)
– Avery's Drug Treatment (Speight, 1997)
– Drug Benefits and Risks (van Boxtel,
Santoso, Edwards, 2002)
Methodology
– Pharmacovigilance (Mann, Andrews, 2002)– Pharmacoepidemiology (Strom, 2000)– The detection of New Adverse Drug Reactions
(Stephens, 2000)– Methodological Approaches in
Pharmacoepidemiology (ARME-P, 1993)– Guide pratique de pharmacovigilance (Bénichou,
1996)– Principios de epidemiologia del medicamento
(Laporte, Tognoni, 1993)
Textbooks
Textbooks
Textbooks
Textbooks
Reference booksAddressing specific problem areas
• A guide to drug eruptions(Bruinsma)
• Adverse Drug Interactions(Griffin, D'Arcy, 1997)
• Drugs in Pregnancy and Lactation (Briggs, Freeman,Yaffe, 1998)
• Drug-induced Ocular Side Effects (Fraunfelder, 2002)
• Adverse Effects of Herbal Drugs (De Smet et al 1992)
• Adverse Events Associated with childhood vaccines (Instit of Med, 1994)
• Responsibility for Drug-Induced Injury (Dukes,
Mildred, Swartz, 1998)
• Safety of Anaesthetic Drugs(Naguib, 1998)
Reference booksAddressing specific problem areas
Reference booksAddressing specific problem areas
References online
• Micromedex– Includes Martindale, PDR, Alternative Medicines
and Index Nominum
• Merck Manual– Includes: The Merck Manual of Diagnosis and
Therapy
• SAM=Scientific American Medicine
Computerized literature screening (1/2)
• Positive– High coverage– High specificity of search
• Negative– Requires equipment & skill– Lack of detail
Computerized literature screening (2/2)
• Medline– Pubmed is using the MeSH (Medical
Subject Headings) terminology.
• EMBASE
• Current Contents on CD
• Reactions Weekly on-line
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
WHO Publications• National Pharmacovigilance Systems (Olsson, 1999)
• Pharmacovigilance in Focus (Meyboom, 2001)
• WHO Pharmaceuticals Newsletter
• WHO Drug Information
• Effective Communications in Pharmacovigilance
• Dialogue in Pharmacovigilance
• Viewpoint
NATIONAL ADR BULLETINS• Presciber Update, New Zealand• Australian Adverse Reactions Bulletin• Signals in Adverse Drug Reactions
Monitoring, The Philippines• Butlletí Groc and many other regional
bulletins, Spain• Information från Läkemedelsverket,
Sweden• Drug Information Bulletin, Tanzania
NATIONAL ADR BULLETINS (2)
• Berita Ubat-Ubatan, Malaysia• Folia Pharmacoterapeutica, Belgium• Canadian Adverse Drug Reaction
Newsletter• TABU, Finland• Drug Safety Newsletter, Ireland• Information on Adverse Reactions to
Drugs, Japan• Adverse Drug Reaction News, Singapore