lesson 5 the role of the neuron in memory formation 2012 sh

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Lesson 5 - The role of Neurons in Memory formation Friday, 13 April 2012

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Page 1: Lesson 5   the role of the neuron in memory formation 2012 sh

Lesson 5 - The role of Neurons in Memory formation

Friday, 13 April 2012

Page 2: Lesson 5   the role of the neuron in memory formation 2012 sh

Last lesson......

From which form of declarative memory is retrieval of information often more difficult? Why?

3 marks

Friday, 13 April 2012

Page 3: Lesson 5   the role of the neuron in memory formation 2012 sh

Last lesson......

From which form of declarative memory is retrieval of information often more difficult? Why?

3 marks

AnswerRetrieval of information is often more difficult from episodic memory. There memories are less well learned, and are more context dependent and state-dependent in nature.

Friday, 13 April 2012

Page 4: Lesson 5   the role of the neuron in memory formation 2012 sh

•Review the function of a neuron•Explain the role of the neuron in memory formation informed by the work of E. Richard Kandel!

Todays lesson............

Friday, 13 April 2012

Page 5: Lesson 5   the role of the neuron in memory formation 2012 sh

Revision - The Neuron

Friday, 13 April 2012

Page 6: Lesson 5   the role of the neuron in memory formation 2012 sh

Kandel found that any experience resulting in memory produces physical changes in the brain at the neuronal level, changes in structure and function of neurons.

Friday, 13 April 2012

Page 7: Lesson 5   the role of the neuron in memory formation 2012 sh

Kandel’s Research on the role of neurons

Eric Kandel studies the sea slug Aplysia for the following reasons:•Very simple nervous system•Only 20,000 neurons•Largest neurons in the world and can be seen with the naked eye

Friday, 13 April 2012

Page 8: Lesson 5   the role of the neuron in memory formation 2012 sh

Studied simple learning and remembering of the gill-withdrawal reflex of Aplysia

Kandel’s experiments

Observed changes at the synapse (i.e. point of communication by adjacent neurons) in the structure and function of neurons in three ways:•Release extra neurotransmitter•Increase number of receptor sites•Growth of new synapses

These changes are called collectively Long Term Potentiation

Friday, 13 April 2012

Page 9: Lesson 5   the role of the neuron in memory formation 2012 sh

Long Term Potentiation

Friday, 13 April 2012

Page 10: Lesson 5   the role of the neuron in memory formation 2012 sh

Friday, 13 April 2012

Page 11: Lesson 5   the role of the neuron in memory formation 2012 sh

Friday, 13 April 2012