lecture16-medical image registration iibagci/teaching/mic16/lec16.pdf · lecture 16: medical image...
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MEDICAL IMAGE COMPUTING (CAP 5937)
LECTURE 16: Medical Image Registration II (Advanced):Deformable Registration
Dr. Ulas BagciHEC 221, Center for Research in Computer Vision (CRCV), University of Central Florida (UCF), Orlando, FL [email protected] or [email protected]
1SPRING 2016
Outline
• Intensity-based deformable registration– Similarity metrics• Standard similarity measures• Probabilistic framework• Pre-processing step• Recent approaches• Linear vs. non-linear approaches
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Requirements on Similarity Measure
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Standard Similarity Measures
• SSD-SAD• Cross correlation• Mutual information• Derivatives
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Difference Measure
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Credit: Itk.org
Limitations of SSD
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Limitations of SSD
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Read: Bagci, U., et al. The role of Intensity Standardization in Medical Image Registration, PRL 2010.
Normalized Cross Correlation (NCC)
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NCC-Example
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Multi-modal Image Registration
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Information Theoretic Approaches• Mutual Information (MI)• Normalized Mutual Information (NMI)
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Preliminary: Histogram Calculation
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Preliminary: Joint Histogram Calculation
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Information Theoretic Approach
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Joint Histogram
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Joint Histogram
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Joint Histogram
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Information Theoretic Approach
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Entropy
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Mutual Information
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Historical Note
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Normalization of MI
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Improvements to MI
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Derivatives of Similarity Measures
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Derivatives of Similarity Measures
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Derivatives of Similarity Measures
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Derivatives of Similarity Measures
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Probabilistic Framework for Image Registration
• Viola, PhD Thesis, 1995• Roche et al 2000• Zollei, PhD Thesis, 2006
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Probabilistic Framework
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MLE Framework for Registration
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Intensity Relationships
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Pre-Processing Steps
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Image Gradients
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Image Gradients
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Image Gradients
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Entropy Images
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Entropy Images
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Entropy Images
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Entropy Images
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Phase-based Registration
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Multi-Resolution Registration
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Attribute Vectors
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Recent Approaches
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Examples
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Minimizing Residual Complexity
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Minimizing Residual Complexity
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Local and Global Statistics
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Local and Global Statistics
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Summary
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Slide Credits and References• Darko Zikic’s MICCAI 2010 Tutorial• Christian Wachingher, MICCAI 2010 Tutorial
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