laura neale. unprotected sex 1 year (unless known problems) primary or secondary predisposing...

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Infertility Management and Referral Laura Neale

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Page 1: Laura Neale.  Unprotected sex 1 year (unless known problems)  Primary or secondary  Predisposing factors ◦ Menstrual cycle ◦ STIs ◦ Previous ectopics

Infertility Management and

Referral

Laura Neale

Page 2: Laura Neale.  Unprotected sex 1 year (unless known problems)  Primary or secondary  Predisposing factors ◦ Menstrual cycle ◦ STIs ◦ Previous ectopics

Unprotected sex 1 year (unless known problems) Primary or secondary Predisposing factors

◦ Menstrual cycle◦ STIs◦ Previous ectopics◦ Galactorrhoea/hirsutism/acne◦ Systemic diseases◦ Drug history (NSAIDs, chemotherapy, neuroleptics)

Lifestyle factors

BMI Features of PCOS

History and Examination

Page 3: Laura Neale.  Unprotected sex 1 year (unless known problems)  Primary or secondary  Predisposing factors ◦ Menstrual cycle ◦ STIs ◦ Previous ectopics

Think in terms of cause

AnovulatoryMale factorUnexplainedTubalOther

Investigations (1)

Page 4: Laura Neale.  Unprotected sex 1 year (unless known problems)  Primary or secondary  Predisposing factors ◦ Menstrual cycle ◦ STIs ◦ Previous ectopics

Day 2-5 FSH and LH Day 21 progesterone

Semen analysis Rubella screen Chlamydia screen

Investigations (2)

Page 5: Laura Neale.  Unprotected sex 1 year (unless known problems)  Primary or secondary  Predisposing factors ◦ Menstrual cycle ◦ STIs ◦ Previous ectopics

If anovulatory◦ TFTs◦ Prolactin◦ Oestradiol◦ Testosterone◦ SHBG

Assess tubal status (unless semen analysis abnormal)

Investigations (3)

Page 6: Laura Neale.  Unprotected sex 1 year (unless known problems)  Primary or secondary  Predisposing factors ◦ Menstrual cycle ◦ STIs ◦ Previous ectopics

Optimise weight Usual lifestyle advise Folic acid Investigative course Costs (emotional and financial) Chances failure (i.e. only 15% success rate

per IVF cycle if age > 36)

Counselling

Page 7: Laura Neale.  Unprotected sex 1 year (unless known problems)  Primary or secondary  Predisposing factors ◦ Menstrual cycle ◦ STIs ◦ Previous ectopics

Any Questions?