launched: 31st may 1911 total lost: 1,502 (68%) passengers lost: 818 (62%) crew lost: 684 (77%)...

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Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: TITANIC

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Page 1: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Launched: 31st May 1911 Total Lost: 1,502 (68%)

Passengers Lost: 818 (62%) Crew Lost: 684 (77%)

TITANIC

Page 2: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

WHY did soooo many die as they awaited rescue in the North Sea?

Page 3: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

WHY did soooo many die as they awaited rescue in the North Sea? HINT: THE NORTH

SEA IS COLD!!!!!

Page 4: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Function of Cellular Respiration…harvesting the harvesting the energyenergy of food of food

for ATP for ATP synthesis… so the synthesis… so the cells have energy cells have energy

for workfor work

Page 5: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC
Page 6: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

WHAT if there is WHAT if there is NO NO electronegativeelectronegative oxygenoxygen to pull to pull electrons electrons down the chain???? down the chain???? Oxidative phosporylation Oxidative phosporylation

STOPS!STOPS!GAAAAK!!!!

Page 7: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Pyruvate

Glucose

CYTOSOL

No O2 presentFermentation

Ethanolor

lactate

Acetyl CoA

MITOCHONDRION

O2 present Cellular respiration

Citricacidcycle

Page 8: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

FermentationFermentation - -

the synthesis of ATP the synthesis of ATP

via. glycolysis via. glycolysis ONLYONLY in the in the absence of oxygenabsence of oxygen

Page 9: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Alcohol fermentation is done by yeast and some kinds of bacteria.

QuickTime™ and a decompressor

are needed to see this picture.

Page 10: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

yeast / bacteria.

The waste products of this process are ethanol and carbon dioxide (CO2).

QuickTime™ and a decompressor

are needed to see this picture.

Page 11: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

yeast / bacteria.

The waste products of this process are ethanol and carbon dioxide (CO2).

Humans have long taken advantage of this process in making bread, beer, and wine.

QuickTime™ and a decompressor

are needed to see this picture.

Page 12: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Alcohol Fermentation -Alcohol Fermentation -

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Page 13: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Carboxyl Carboxyl (X2)(X2) to CO to CO2 2 (X2)(X2) - -

Page 14: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Acetaldehyde produced (Acetaldehyde produced (X2)X2) --

Page 15: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Acetaldehyde (Acetaldehyde (X2)X2) REDUCEDREDUCED --

Page 16: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Ethanol Produced (Ethanol Produced (X2)X2) - -

Page 17: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Alcohol Fermentation -Alcohol Fermentation -

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Page 18: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

QuickTime™ and a decompressor

are needed to see this picture.

Page 19: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

FermentationFermentation - - after glycolysis after glycolysis

(no O(no O2 2 available)available)Lactic acid fermentation is done by some fungi, some bacteria like in yogurt, and sometimes by our muscles.

Page 20: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

FermentationFermentation - - after glycolysis after glycolysis

(no O(no O2 2 available)available)Lactic acid fermentation is done by some fungi, some bacteria like in yogurt, and sometimes by our muscles.

Normally our muscles do cellular respiration like the rest of our bodies, using O2 supplied by our lungs and blood. However, under greater exertion when the oxygen supplied by the lungs and blood system can’t get there fast enough to keep up with the muscles’ needs, our muscles can switch over and do lactic acid fermentation. In the process of lactic acid fermentation, the 3-carbon pyruvic acid molecules are turned into lactic acid.

Page 21: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

LacticLactic AcidAcid FermentationFermentation --

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Page 22: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Pyruvate (Pyruvate (X2)X2) reduced by reduced by NADH-NADH-

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Page 23: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Lactate (Lactate (X2) formedX2) formed - -

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Page 24: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

FermentationFermentation - -

+ 2 H+

2 NADH2 NAD+

2 ATP2 ADP + 2 P

2 Pyruvate

2 Lactate

Lactic acid fermentation

Glucose Glycolysis

Page 25: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

QuickTime™ and a decompressor

are needed to see this picture.

Page 26: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC
Page 27: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

FermentationFermentation - - extension of extension of

glycolysisglycolysisAnaerobic catabolism of organic molecules.•Yields only 2 ATP’s

•Electrons are transferred from NADH to pyruvate (not the e- transport chain)

Page 28: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC
Page 29: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC
Page 30: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC
Page 31: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

Figure 9.18 Pyruvate as a key juncture in catabolism

aerobiaerobicc

anaerobic

Page 32: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

FermentatiFermentationon

Page 33: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC

no oxygen

3.5bya

Page 34: Launched: 31st May 1911 Total Lost: 1,502 (68%) Passengers Lost: 818 (62%) Crew Lost: 684 (77%) TITANIC