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  • Late-Onset Sepsis...Premature infants have up to a 26.0% chance of developing late-onset sepsis, a leading cause of mortality in neonatal intensive care units (NICUs). 5 This condition
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Why it matters: A long-term perspective Premature infants have up to a 26.0% chance of developing late-onset sepsis, a leading cause of mortality in neonatal intensive care units (NICUs). 5 This condition is associated with a series of adverse outcomes that diminish an infant’s prospects for a healthy future: Achieve better outcomes with Prolacta As hospitals seek to decrease central venous line days and drive down the incidence of late-onset sepsis in premature infants—as well as lower the overall cost of care—nutrition has a vitally important role to play. Prolacta’s human milk–based fortifiers, fed as part of an EHMD, have transformed health outcomes for tens of thousands of premature infants. Clinicians are able to get to full feeds faster 7 and remove the central line sooner, making a sepsis diagnosis less likely. Late-onset sepsis, a serious bacterial infection afflicting premature infants, is one of the most severe complications of prematurity. Appropriate nutrition is essential to help put these infants on track for positive outcomes, but not all nutrition is created equal. With human milk–based fortifiers from Prolacta Bioscience ® as part of an exclusive human milk diet (EHMD), premature infants are less likely to develop late-onset sepsis than those who are fed cow milk–based fortifiers. 1-4 Late-Onset Sepsis: Reducing Risks, Improving Outcomes With an Exclusive Human Milk Diet Predisposition to other morbidities Longer NICU stays Higher overall NICU costs Neurodevelopmental disabilities Higher educational and societal costs due to disability Potential complications of late-onset sepsis 6 Increased ventilation use Advancing the Science of Human Milk ®

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  • Why it matters: A long-term perspectivePremature infants have up to a 26.0% chance of developing late-onset sepsis, a leading cause of mortality in neonatal intensive care units (NICUs).5 This condition is associated with a series of adverse outcomes that diminish an infant’s prospects for a healthy future:

    Achieve better outcomes with Prolacta As hospitals seek to decrease central venous line days and drive down the incidence of late-onset sepsis in premature infants—as well as lower the overall cost of care—nutrition has a vitally important role to play. Prolacta’s human milk–based fortifiers, fed as part of an EHMD, have transformed health outcomes for tens of thousands of premature infants. Clinicians are able to get to full feeds faster7 and remove the central line sooner, making a sepsis diagnosis less likely.

    Late-onset sepsis, a serious bacterial infection afflicting premature infants, is one of the most severe complications of prematurity. Appropriate nutrition is essential to help put these infants on track for positive outcomes, but not all nutrition is created equal. With human milk–based fortifiers from Prolacta Bioscience® as part of an exclusive human milk diet (EHMD), premature infants are less likely to develop late-onset sepsis than those who are fed cow milk–based fortifiers.1-4

    Late-Onset Sepsis: Reducing Risks, Improving Outcomes With an Exclusive Human Milk Diet

    Predisposition to other morbidities

    Longer NICU stays

    Higher overall NICU costs

    Neurodevelopmental disabilities

    Higher educational and societal costs due

    to disability

    Potential complications of late-onset sepsis6

    Increased ventilation use

    Advancing the Science of Human Milk®

  • What the research showsStudies showed that hospitals effectively reduced the development of late-onset sepsis by feeding Prolacta’s well-tolerated, human milk–based products to premature infants as part of an EHMD.1-3

    1 O’Connor DL, Kiss A, Tomlinson C, et al. Nutrient enrichment of human milk with human and bovine milk-based fortifiers for infants born weighing


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