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    LABORATORY VALUES

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    PYRAMID POINTS Explain purpose of test to client

    Obtain informed consent if required

    Inform client of specific test preparation

    Initiate standard (universal) or otherprecautions as necessary

    Maintain asepsis

    Instruct client in post-test procedures &need for follow-up

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    PYRAMID POINTS Note if the laboratory value is abnormal Monitor for signs & symptoms that occur as

    a result of the abnormality Report the significant results to the

    physician

    Initiate prescribed interventions based onthe laboratory results

    Document the effectiveness of interventions

    & follow-up laboratory studies

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    VENIPUNCTURE SITES

    From Leahy, J. & Kizilay, P. (1998). Foundations of nursing practice.Philadelphia: W.B. Saunders, p. 814. (Figure 28-10)

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    NORMAL ADULT

    ELECTROLYTE VALUES Sodium: 135 to 145 mEq/L

    Potassium: 3.5 to 5.1 mEq/L Chloride: 98 to 107 mEq/L

    Bicarbonate (venous): 22 to 29

    mEq/L

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    ELECTROLYTES: SERUM

    SODIUM (Na) DESCRIPTION

    Maintains osmotic pressures & acid-basebalance & assists in transmission ofnerve impulses

    NURSING CONSIDERATION

    Drawing blood samples proximal to anIV infusion of sodium chloride will falselyelevate results

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    ELECTROLYTES: SERUM POTASSIUM (K)

    A major intracellular cation that regulates

    cellular H2O balance, electrical conduction in

    muscle cells, & acid-base balance The body obtains K through dietary ingestion, &

    the kidneys either preserve or excrete Kdepending on cellular need

    K levels are used to evaluate cardiac function,renal function, gastrointestinal (GI) function, &the need for IV replacement therapy

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    ELECTROLYTES: SERUM POTASSIUM

    (K)

    NURSING CONSIDERATIONS Use of a tourniquet & pumping the hand prior

    to venous sampling can increase the value

    Do not draw blood from a site where an IVinfusion exists

    If the client is receiving K, note on thelaboratory form

    Clients w/ elevated white blood cell counts &platelet counts may have falsely elevated Klevels

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    ELECTROLYTES: SERUM

    CHLORIDE DESCRIPTION

    Functions in counterbalancing cationssuch as sodium & acts as a bufferduring oxygen & carbon dioxideexchange in red blood cells

    Aids in digestion & maintaining osmoticpressure & water balance

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    ELECTROLYTES: SERUM

    CHLORIDE NURSING CONSIDERATIONS

    Draw blood from an extremity that doesnot have saline infusing into it

    Do not allow the client toclench/unclench the hand prior to the

    blood drawAny condition accompanied by

    prolonged vomiting, diarrhea, or bothwill alter levels

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    NORMAL VALUES:

    COAGULATION STUDIESActivated partial thromboplastin time

    (aPTT)

    20 to 36 seconds depending on the typeof activator used

    Prothrombin time (PT)

    Adult male, 9.6 to 11.8 seconds

    Adult female, 9.5 to 11.3 seconds

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    NORMAL VALUES:

    COAGULATION STUDIES International normalized ratio (INR)

    2.0 to 3.0 for standard warfarin sodium(Coumadin) therapy

    3.0 to 4.5 for high dose warfarin sodium(Coumadin) therapy

    Clotting time: 8 to 15 minutes

    Platelet count: 150,000 to 400,000cells/L

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    ACTIVATED PARTIAL

    THROMBOPLASTIN TIME (aPTT)

    DESCRIPTION

    Most commonly used to monitor heparintherapy & screen for coagulation disorders

    Screens for deficiencies & inhibitors of allfactors except VII & XIII

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    ACTIVATED PARTIAL

    THROMBOPLASTIN TIME (aPTT) NURSING CONSIDERATIONS If the client is on intermittent heparin therapy,

    draw the blood sample one hour prior to the next

    scheduled dose Do not draw samples from an arm in which

    heparin is infusing

    Transport specimen to laboratory immediately

    The aPTT should be between 1.5 & 2.5 times thenormal when the client is on heparin therapy; ifthe value is prolonged, initiate bleedingprecautions

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    PROTHROMBIN TIME (PT) & INTERNATIONAL

    NORMALIZED RATIO (INR) DESCRIPTION

    Prothrombin is a vitamin K-dependent

    glycoprotein produced by the liver that isnecessary for firm fibrin clot formation

    Each laboratory establishes a normal value

    or control based on the method used toperform the test (PT)

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    PROTHROMBIN TIME (PT) &INTERNATIONAL NORMALIZED RATIO (INR)

    DESCRIPTION

    The PT measures the amount of time it

    takes for clot formation & is used tomonitor response to warfarin sodium(Coumadin) therapy or to screen fordysfunction of the extrinsic systemresulting from liver disease, vitamin Kdeficiency, or disseminated intravascularcoagulation (DIC)

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    PROTHROMBIN TIME (PT) & INTERNATIONALNORMALIZED RATIO (INR)

    DESCRIPTION

    A PT value w/in 2 seconds (plus or minus)

    of the control is considered normal The INR standardizes the PT ratio & is

    calculated in the laboratory setting by

    raising the observed PT ratio to the powerof the International Sensitivity Indexspecific to the thromboplastin reagent used

    PROTHROMBIN TIME (PT) &

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    PROTHROMBIN TIME (PT) &INTERNATIONAL NORMALIZED RATIO(INR)

    NURSING CONSIDERATIONS

    A baseline PT should be drawn before startinganticoagulation therapy

    Note the time of collection on the laboratoryform

    Provide direct pressure to the site for 3 to 5

    minutes if a coagulation defect is present Concurrent warfarin sodium (Coumadin) therapy

    w/ heparin therapy can lengthen the PT for up to5 hours after dosing

    PROTHROMBIN TIME (PT) &

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    PROTHROMBIN TIME (PT) &INTERNATIONAL NORMALIZEDRATIO (INR)

    NURSING CONSIDERATIONS

    Diets high in green leafy vegetables can

    increase the absorption of vitamin K, whichshortens the PT

    A PT greater than 30 seconds places the

    client at risk for hemorrhage Oral anticoagulation therapy usually

    maintains the PT at 1.5 to 2 times thelaboratory control value

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    CLOTTING TIME

    DESCRIPTION

    Measures the time required for the interaction of

    all factors involved in the clotting process NURSING CONSIDERATIONS

    The client should not receive heparin therapy

    for 3 hours prior to specimen collection The test result is prolonged by any

    anticoagulant therapy, test tube agitation, orhigh temperature changes that may affect the

    specimen

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    PLATELET COUNT

    DESCRIPTION

    Platelets are produced by the bone marrow tofunction in hemostasis

    NURSING CONSIDERATIONS

    Monitor for bleeding in clients w/ knownthrombocytopenia

    High altitudes, chronic cold weather, & exerciseincrease platelet counts

    Bleeding precautions should be instituted in

    clients w/ a low platelet count

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    NORMAL VALUES:GASTROINTESTINAL STUDIES

    Albumin: 3.4 to 5 g/dL

    Alkaline phosphatase: 4.5 to 13 King-Armstrongunits/dL

    Ammonia: 35 to 65 g/dL

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    NORMAL VALUES:GASTROINTESTINAL STUDIES

    Amylase: 24 to 151 IU/L

    Bilirubin

    Direct: 0 to 0.3 mg/dL

    Indirect: 0.1 to 1.0 mg/dL

    Total: less than 1.5 mg/dL

    Lipase: 10 to 140 U/L

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    NORMAL VALUES:GASTROINTESTINAL STUDIES

    Uric acid Male: 4.5 to 8 mg/dL

    Female: 2.5 to 6.2 mg/dL

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    ALBUMIN

    A main plasma protein of blood Maintains oncotic pressure & transports

    bilirubin, fatty acids, medications, hormones, &

    other substances that are insoluble in water NURSING CONSIDERATIONS

    Draw from an extremity the does not have an

    IV infusing into it Instruct the client to consume a low-fat diet on

    the day of the test

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    ALKALINE PHOSPHATASEAn enzyme normally found in bone, liver,

    intestine, & placenta The level rises during periods of bone growth, liver

    disease, & bile duct obstruction NURSING CONSIDERATIONS

    The client may need to fast 10 to 12 hours prior tothe test

    Hepatotoxic medications administered w/in 12hours prior to specimen collection invalidate the test

    Transport specimen to laboratory immediately

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    AMMONIA DESCRIPTION

    A waste product from nitrogen breakdownduring protein metabolism

    Metabolized by the liver & excreted by thekidneys as urea

    Elevated levels due to hepatic dysfunction

    may lead to encephalopathy Not a reliable indicator of hepatic coma

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    AMMONIA

    NURSING CONSIDERATIONS

    Instruct client to fast, except for water,& refrain from smoking for 8 to 10 hoursprior to the test

    Place the specimen in an ice water bath

    Transport to the laboratory immediately

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    AMYLASEAn enzyme produced by the pancreas &

    salivary glands that aids in the digestionof complex carbohydrates & is excretedby the kidneys

    In acute pancreatitis, the amylase level isgreatly increased; the level starts rising in

    3 to 6 hours after the onset of pain, peaksat about 24 hours, & returns to normal in 2to 3 days after the onset of pain

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    AMYLASE

    NURSING CONSIDERATIONS

    List medications that the client has

    taken 24 hours prior to the test on thelaboratory form

    Note that many medications may cause

    false-positive or false-negative results Results are invalidated if the specimen

    was obtained less than 72 hours aftercholecystography w/ radiopaque dyes

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    BILIRUBIN

    Produced by the liver, spleen, & bone marrow &is also a by-product of hemoglobin breakdown

    Total bilirubin levels can be broken down intodirect bilirubin, which is primarily excreted viathe intestinal tract, & indirect bilirubin, whichcirculates primarily in the bloodstream

    Total bilirubin levels rise w/ any type ofjaundice, whereas direct & indirect levels risedepending on the etiology of the jaundice

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    BILIRUBIN

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    BILIRUBIN

    NURSING CONSIDERATIONS Instruct the client to eat a diet low in yellow

    foods such as carrots, yams, yellow beans, &

    pumpkins for 3 to 4 days before sampling Instruct the client to fast for 4 hours before

    sampling

    Note that results will be elevated w/ the use ofalcohol, morphine, theophylline, ascorbic acid, &aspirin

    Note that results are invalidated if the client

    received a radioactive scan w/in 24 hours prior tothe test

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    LIPASE

    DESCRIPTION

    A pancreatic enzyme that changes fats

    & triglycerides into fatty acids & glycerol

    Elevated lipase levels occur in pancreaticdisorders; elevations may not occur until

    24 to 36 hours after the onset of illness& may remain elevated for up to 14days

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    LIPASE

    NURSING CONSIDERATIONS

    Endoscopic retrograde

    cholangiopancreatography (ERCP) mayincrease lipase activity

    Traumatic venipuncture can inhibit

    lipase activity

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    LIPIDS

    Blood lipids consist primarily of cholesterol,triglycerides, & phospholipids

    Lipid assessment includes total cholesterol,high-density lipoprotein (HDL), low-densitylipoprotein (LDL), & triglycerides

    Cholesterol is present in all body tissues & is a

    major component of low-density lipoproteins(LDL), brain & nerve cells, cell membranes, &some gallstones

    LIPIDS

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    LIPIDS

    Triglycerides comprise a major part of verylow-density lipoproteins (VLDL) & a small part

    of low-density lipoproteins (LDL) Triglycerides are synthesized in the liver from

    fatty acids, protein, & glucose, & are obtainedfrom the diet

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    LIPIDS

    NURSING CONSIDERATIONS Oral contraceptives may increase the levels of

    lipids in the serum

    Instruct the client to fast from foods & fluids,except for water, for 12 to 14 hours & fromalcohol for 24 hours prior to the test

    Instruct the client that the evening meal prior tothe test should be free from high-cholesterolfoods

    Cholesterol levels tend to decrease temporarily

    w/ major illness or surgery

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    PROTEIN

    Reflects the total amount of albumin &globulins in the serum

    Regulates osmotic pressure & is comprised ofcoagulation factors for hemostasis, enzymes,hormones, tissue growth & repair, & pHbuffers

    NURSING CONSIDERATIONS

    Do not draw in an extremity w/ an IV infusion Instruct the client to avoid a high-fat diet for

    8 hours prior to the test

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    URIC ACID

    Elevated amounts deposit in joints & softtissue & cause gout

    Conditions of fast cell turnover, as well asslowed renal excretion of uric acid, may cause

    uricemia Elevated amounts of urinary uric acid

    precipitate into urate stones in the kidneys

    NURSING CONSIDERATIONS Instruct the client to fast for 8 hours prior to

    the test

    Aminophylline, caffeine, & vitamin C may cause

    falsely elevated results

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    NORMAL VALUES: GLUCOSESTUDIES

    Fasting blood glucose: 70 to 110 mg/dL

    Glucose monitoring (capillary blood): 60 to110 mg/dL

    Glycosylated hemoglobin

    Values are expressed as a % of the total HgbDiabetic w/ good control: 7.5% or less

    Diabetic w/ fair control: 7.6 to 8.9%

    Diabetic w/ poor control: 9% or greater

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    NORMAL VALUES: GLUCOSESTUDIES

    GLUCOSE TOLERANCE TEST, ORAL

    Baseline fasting: 70 to 110 mg/dL

    30 minute fasting: 110 to 170 mg/dL

    60 minute fasting: 120 to 170 mg/dL

    90 minute fasting: 100 to 140 mg/dL

    120 minute fasting: 70 to 120 mg/dL

    Glucose, 2 hour postprandial: < 140 mg/dL

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    (FBS)

    Glucose is a monosaccharide found in fruits & isformed from the digestion of carbohydrates &the conversion of glycogen by the liver

    Glucose is the bodys main source of cellularenergy & is essential for brain & erythrocytefunction

    FBS levels are used to help diagnose diabetesmellitus & hypoglycemia

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    (FBS)

    NURSING CONSIDERATIONS

    Instruct the client to fast for 8 to 12

    hours prior to the test Instruct the client w/ diabetes mellitus

    to w/hold morning insulin or oral

    hypoglycemic medication until after theblood is drawn

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    HEMOGLOBIN

    Glycosylated hemoglobin is blood glucosebound to hemoglobin

    HbA1c (glycosylated hemoglobin A) is a

    reflection of how well blood glucose levels havebeen controlled for up to the prior 4 months

    Hyperglycemia in diabetics is usually a cause ofan increase in HbA1c

    NURSING CONSIDERATION Fasting is not required prior to the test

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    GLUCOSE TOLERANCE TEST (GTT)

    NURSING CONSIDERATIONS

    Instruct the client to eat a high-

    carbohydrate (200 to 300 g) diet for 3days before the test

    Instruct the client to avoid alcohol,

    coffee, & smoking for 36 hours beforetesting

    Instruct the client to fast for 10 to 16hours prior to the test

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    GLUCOSE TOLERANCE TEST (GTT)

    NURSING CONSIDERATIONS

    Instruct the client to avoid strenuous exercise for8 hours before & after the test

    Instruct the client w/ diabetes mellitus to w/holdmorning insulin or oral hypoglycemic medication

    Instruct the client that the test will take 3 to 5

    hours, requires intravenous or oral administrationof glucose, & multiple blood samples

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    NORMAL VALUES: RENALFUNCTION STUDIES

    Serum creatinine: 0.6 to 1.3 mg/dL

    Blood urea nitrogen (BUN): 8 to 25mg/dL

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    SERUM CREATININE

    DESCRIPTIONA very specific indicator of renal function,

    revealing the balance between creatinine

    formation & excretion Increased levels indicate a slowing of the

    glomerular filtration rate

    NURSING CONSIDERATION Instruct the client to avoid excessive

    exercise for 8 hours & avoid excessive redmeat intake for 24 hours before the test

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    BLOOD UREA NITROGEN (BUN)

    Urea is normally freely filtered through the renalglomeruli, w/ a small amount reabsorbed in thetubules & the remainder excreted in the urine

    Elevated values may be a result of prerenal,renal, or postrenal causes

    NURSING CONSIDERATION Both creatinine levels & urea nitrogen levels

    should be analyzed when evaluating renalfunction

    O S S

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    NORMAL VALUES: SERUMENZYMES/CARDIAC MARKERS

    Creatine kinase (CK): 26 to 174 U/L

    CK isoenzymes

    CK-MB: 0 to 5% of total CK-MM: 95 to 100% of total

    CK- BB: 0%

    NORMAL VALUES SERUM

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    NORMAL VALUES: SERUMENZYMES/CARDIAC MARKERS

    Troponins Troponin I: less than 0.6 ng/mL; greater than

    1.5 ng/mL is consistent w/ a myocardial

    infarction Troponin T: greater than 0.1 to 0.2 ng/mL is

    consistent w/ a myocardial infarction

    NORMAL VALUES SERUM

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    NORMAL VALUES: SERUMENZYMES/CARDIAC MARKERS

    Lactate dehydrogenase (LDH): 70 to 200IU/L

    LDH isoenzymes LDH 1: 14 to 26 %

    LDH 2: 29 to 39 %

    LDH 3: 20 to 26 % LDH 4: 8 to 16 %

    LDH 5: 6 to 16 %

    CREATINE KINASE (CK)

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    CREATINE KINASE (CK)

    An enzyme found in muscle & brain tissue &reflects tissue catabolism due to cell trauma

    The test is performed to detect myocardial orskeletal muscle damage or central nervous systemdamage

    Isoenzymes include CK-MB (cardiac), CK-BB(brain), & CK-MM (muscles)

    CK-MB is found mainly in cardiac muscle, CK-BB isfound mainly in brain tissue, & CK-MM is foundmainly is skeletal muscle

    CREATINE KINASE (CK)

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    CREATINE KINASE (CK)

    NURSING CONSIDERATIONS If the test is to evaluate skeletal muscle,

    instruct the client to avoid strenuous

    physical activity for 24 hours prior to thetest

    Instruct the client to avoid ingestion ofalcohol for 24 hours prior to the test

    Invasive procedures & IM injections mayfalsely elevate CK levels

    TROPONINS

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    TROPONINS

    Troponin is a regulatory protein found instriated muscle

    The troponins function together in thecontractile apparatus for striated muscle in

    skeletal muscle & in the myocardium Increased amounts of troponins are released

    into the bloodstream when an infarction causesdamage to the myocardium

    Serial measurements are important to compareto a baseline test

    NURSING CONSIDERATION

    Client does not need to fast

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    LDH)

    The isoenzymes that are particularly affected w/acute myocardial infarction are the LDH1 & LDH2

    This enzyme begins to elevate approximately 24hours after myocardial infarction & peaks in 48 to72 hours; thereafter, it returns to normal, usuallyw/in 7 to 14 days

    The presence of an LD flip (when LD1 is higherthan LD2), is helpful in diagnosing a myocardialinfarction

    LACTATE DEHYDROGENASE (LD OR

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    (LDH)

    NURSING CONSIDERATIONS

    LDH isoenzymes should be interpreted

    in view of the clinical findings Testing should be repeated on 3

    consecutive days

    NORMAL VALUES: ERYTHROCYTE

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    STUDIES

    Erythrocyte sedimentation rate (ESR): 0to 30 mm/hour depending on age ofclient

    Hemoglobin Male: 14 to 16.5 g/dL

    Female: 12 to 15 g/dL

    Hematocrit Male: 42 to 52%

    Female: 35 to 47%

    NORMAL VALUES:

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    NORMAL VALUES:ERYTHROCYTE STUDIES

    Serum iron

    Male: 65 to 175 g/dL

    Female: 50 to 170 g/dL

    Red blood cell (RBC) count

    Female: 4 to 5.5 million/L

    Male: 4.5 to 6.2 million/L

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    ERYTHROCYTE SEDIMENTATION RATE

    DESCRIPTION

    The rate at which erythrocytes settle out

    of anticoagulated blood in 1 hour Not diagnostic of any particular disease

    but indicates that a disease process isongoing

    NURSING CONSIDERATION

    Fasting is not necessary, but a fattymeal may cause plasma alterations

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    HEMOGLOBIN & HEMATOCRIT

    Hemoglobin is the main component oferythrocytes & serves as the vehicle for thetransportation of oxygen & carbon dioxide Hemoglobin determinations are important in

    determining anemia

    Hematocrit determines red blood cell mass & isan important measurement in thedetermination of anemia or polycythemia

    NURSING CONSIDERATION Fasting is not required

    SERUM IRON

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    SERUM IRON

    DESCRIPTION

    Iron is mostly found in hemoglobin

    Iron acts as a carrier of oxygen from the lungs

    to the tissues & indirectly aids in the return ofcarbon dioxide to the lungs

    Aids in diagnosing anemias & hemolytic

    disorders NURSING CONSIDERATION

    Level will be increased if the client has

    ingested iron prior to the test

    RED BLOOD CELL (RBC)

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    RED BLOOD CELL (RBC)COUNT

    DESCRIPTION RBCs function in hemoglobin transport, which

    results in delivery of oxygen to the body

    tissues RBCs are formed by red bone marrow, have a

    life span of 120 days, & are removed from theblood by the liver, spleen, & bone marrow

    Aid in diagnosing anemias & blood dyscrasias

    NURSING CONSIDERATION Fasting is not required

    NORMAL VALUES:

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    NORMAL VALUES:ELEMENTS

    Calcium: 8.6 to 10.0 mg/dL

    Magnesium: 1.6 to 2.6 mg/dL

    Phosphorus: 2.7 to 4.5 mg/dL

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    CALCIUM Functions in bone formation, nerve impulse

    transmission, & contraction of myocardial& skeletal muscles

    Aids in blood clotting by converting

    prothrombin to thrombin NURSING CONSIDERATIONS

    Instruct the client to eat a diet w/ normalcalcium levels (800 mg/day) for 3 daysbefore the test

    Instruct the client that fasting may berequired for 8 hours prior to the test

    MAGNESIUM

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    MAGNESIUM

    Magnesium is needed in the blood-clottingmechanism, regulates neuromuscularactivity, acts as a cofactor that modifiesthe activity of many enzymes, & has an

    effect on the metabolism of calcium

    NURSING CONSIDERATIONS

    Prolonged use of magnesium products will

    cause increased levels Long-term total parenteral nutrition

    therapy or excessive loss of body fluidsmay cause decreased levels

    PHOSPHORUS

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    PHOSPHORUS

    DESCRIPTION

    Important in bone formation, energystorage & release, urinary acid-base

    buffering, & carbohydrate metabolism

    Absorbed from food & excreted by thekidneys

    High concentrations of phosphorus arestored in bone & skeletal muscle

    NURSING CONSIDERATION

    Instruct the client to fast prior to the test

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    THYROID STUDIES

    DESCRIPTION

    Performed if a thyroid disorder is

    suspected Helpful to differentiate primary thyroid

    disease from secondary causes & fromabnormalities in thyroxine-binding

    globulin levels

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    THYROID STUDIES

    NORMAL VALUES Thyroid-stimulating hormone (thyrotropin;

    TSH): 0.2 to 5.4 U/mL Thyroxine (T4): 5.0 to 12.0 g/dL

    Thyroxine, free (FT4): 0.8 to 2.4 ng/dL

    Triiodothyronine (T3): 80 to 230 ng/dL

    NURSING CONSIDERATION Test results are invalid if the client had

    undergone a radionuclide scan w/in 7 days priorto the test

    WHITE BLOOD CELL (WBC)

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    WHITE BLOOD CELL (WBC)COUNT

    DESCRIPTION

    White blood cells function in the bodys

    immune defense system The WBC count assesses each leukocyte

    distribution (differentiation)

    NORMAL VALUE 4500 to 11,000/L

    NORMAL ADULT WHITE

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    NORMAL ADULT WHITEBLOOD CELL DIFFERENTIAL

    Neutrophils: 56% or 1800 to 7800/L

    Bands: 3% or 0 to 700/L Eosinophils: 2.7% or 0 to 450/L

    Basophils: 0.3% or 0 to 200/L

    Lymphocytes: 34% or 1000 to4800/L

    Monocytes: 4% or 0 to 800/L

    WHITE BLOOD CELL (WBC)

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    WHITE BLOOD CELL (WBC)COUNT

    NURSING CONSIDERATIONS

    Ashift to the leftmeans there is an increasednumber of immature neutrophils in the peripheral

    blood

    A low total WBC count w/ a left shift indicates arecovery from bone marrow depression or an

    infection of such intensity that the demand forneutrophils in the tissue is greater than the capacityof the bone marrow to release them in thecirculation

    WHITE BLOOD CELL (WBC)

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    WHITE BLOOD CELL (WBC)COUNT

    NURSING CONSIDERATIONS

    A high total WBC count w/ a left shift indicates

    an increased release of neutrophils by the bonemarrow in response to an overwhelminginfection or inflammation

    A shift to the right means cells have morethan the usual number of nuclear segments;found in liver disease, Down syndrome, ormegaloblastic & pernicious anemia

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    HEPATITIS TESTS

    DESCRIPTION

    Tests include radioimmune assay (RIA),

    enzyme-linked immunosorbent assay(ELISA), or microparticle enzymeimmunoassay (MEIA)

    Serologic tests for specific hepatitis virusmarkers assist in defining the specifictype of hepatitis

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    HEPATITIS TESTSVALUES

    The presence of IgM antibody to hepatitis A virus(IgM anti-HAV) & the total antibody to hepatitis A

    virus (total anti-HAV) identify the disease Detection of core antigen (HBcAg), envelope

    antigen (HBeAg), & surface antigen (HBsAg), ortheir corresponding antibodies, constitutes hepatitis

    B assessment Hepatitis C is confirmed by the presence of

    antibodies to hepatitis C (anti-HCV)

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    HEPATITIS TESTS

    VALUES Serologic hepatitis delta virus (HDV)

    determination is made by detection of the

    hepatitis D antigen (HDAg) early in thecourse of the infection & by detection ofanti-HDV antibody in the later diseasestages

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    HEPATITIS TESTS

    VALUES Specific serologic tests for hepatitis E virus

    (HEV) include detection of IgM & IgG

    antibodies to hepatitis E (anti-HEV) Hepatitis G (HGV) has been found in some

    blood donors, IV drug users, hemodialysisclients, & clients w/ hemophilia; however,

    HGV does not appear to cause significant liverdisease

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    HEPATITIS TESTS

    NURSING CONSIDERATION

    If using RIA technique, the injection of

    radionuclides w/in 1 week prior to thetest may falsely elevate results

    NORMAL ADULT VALUES:

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    NORMAL ADULT VALUES:URINE TESTS

    Chloride: 110 to 250 mEq/24 hr

    Magnesium: 7.3 to 12.2 mg/dL/day

    Potassium: 25 to 125 mEq/24 hr

    NORMAL ADULT VALUES:

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    NORMAL ADULT VALUES:URINE TESTS

    Protein: 40 to 150 mg/24 hr

    Sodium: 40 to 220 mEq/24 hr

    Uric acid: 250 to 750 mg/24 hr pH: 4.5 to 7.8

    Specific gravity: 1.016 to 1.022

    Th ti M di ti

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    Therapeutic Serum Medication Levels

    Acetaminophen (Tylenol): 10 to 20 g/mL

    Carbamazepine (Tegretol): 5 to 12 g/mL

    Digoxin (Lanoxin): 0.5 to 2.0 g/mL Gentamicin (Garamycin): 5 to 10 g/mL

    Lithium (Lithobid): 0.5 to 1.3 mEq/L

    Magnesium sulfate: 4 to 7 mg/dL

    Therapeutic Serum Medication

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    Therapeutic Serum MedicationLevels

    Phenytoin (Dilantin): 10 to 20 g/mL

    Theophylline (Aminophylline, Theo-Dur): 10

    to 20 g/mL

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