Laboratory System Integration:

The Evolution Of LIMS

Michael S. Zachowski, Robert D. Walla, Richard P. AlbertAstrix Technology Group

175 May Street Edison, NJ 08037

Definition

The Integration Of Laboratory Source The Integration Of Laboratory Source Systems To Facilitate Access To Data Across Systems To Facilitate Access To Data Across The Enterprise. The Enterprise.

The Integration Of Laboratory Source The Integration Of Laboratory Source Systems To Facilitate Access To Data Across Systems To Facilitate Access To Data Across The Enterprise. The Enterprise.

LSI - Laboratory System IntegrationLSI - Laboratory System IntegrationLSI - Laboratory System IntegrationLSI - Laboratory System Integration

LIMS and LSILIMS and LSI

LIMS Is A Valuable Tool To Manage The Collection, Analysis And Reporting Of Scientific Data

Typically Installed As Point Source Solution Business Case And Regulatory Requirements (21

CFR Subpart 11, CROMERR) Increasing The Need For Integrated Systems

Laboratory System Integration (LSI) Increases The Value Of Data Contained In LIMS

Commercial LIMS ProductsCommercial LIMS Products

Instrument Manufacturers Independent LIMS Companies Organizations Must Customize To

Accommodate Their Work Processes Often Not Integrated With Existing Systems

Laboratory Systems Integration Laboratory Systems Integration

Many Manual Data Collection Processes Still Exist In The Modern Laboratoryo Sample Prep Logs o QA/QC Logso Physical Testso Observational Analysis

Electronic Laboratory Notebooks Potential Solution

Integration With Other Enterprise Solutions (Formulations, SCADA, Plant Data) Still Required

Problem Statement

LIMS Typically Exist As Stand Alone LIMS Typically Exist As Stand Alone Solutions, Not Integrated With Solutions, Not Integrated With Enterprise Applications Limiting The Enterprise Applications Limiting The Value Of The DataValue Of The Data

LIMS Typically Exist As Stand Alone LIMS Typically Exist As Stand Alone Solutions, Not Integrated With Solutions, Not Integrated With Enterprise Applications Limiting The Enterprise Applications Limiting The Value Of The DataValue Of The Data

Laboratory System Integration Laboratory System Integration BenefitsBenefits

Provides Link Between R&D And Manufacturing Reduce Rework Increase Quality Improve Customer Service Reduces Costs

Laboratory Systems IntegrationLaboratory Systems IntegrationChallengesChallenges

Remote Data/Facilities Manual Data Collection Security Issues Inconsistent Architecture Of Source

Systems

Successful Approaches To Successful Approaches To Laboratory Systems Integration Laboratory Systems Integration

Identify Business Case And User Identify Business Case And User

RequirementsRequirements

Leverage Existing Source Systems Leverage Existing Source Systems

Modular Development To Allow For Future Modular Development To Allow For Future

Functionality Functionality

Rapid Application Development and Rapid Application Development and

DeploymentDeployment

Life Cycle Planning And SupportLife Cycle Planning And Support

Example ProjectExample Project

Integrated Commercial Electronic Notebook Data Capture Product (FieldNotes) That Collects GLP Data With Commercial LIMS Via Customized LabNotes System.

Developed ReportWriter Functionality To Automate The Submission Of Chemical Registrations To Regulatory Agencies.

Astrix Agrichemical Suite

LabNotes RepositoryDatabase

FieldNotes RepositoryDatabase

Email FileTransfer

Astrix Report Writer

FieldNotes RemoteData Collection

Example ProjectExample Project

Confidential Client-Coatings

Information Management System That Integrates Formulation, Manufacturing and Analytical Databases.

Automated Collection of Physical Test, Performance and Exposure Data Via PDAs Into A Centralized Database Repository.

Coating Data WarehouseCoating Data WarehouseSystem TopologySystem Topology

Plant LIMS

Plant LIMS

Formulations Db

Test Data Entry Via Palm

Data Warehouse

Data Access Via Web

DesktopApplication for

Excel output andsynchronization

Example ProjectExample Project

Confidential Client-Chemical Data Warehouse System

Information Management System That Integrates Formulation, Manufacturing, Physical Testing and Analytical Databases.

Web Application Allows Scientists And Engineers From Corporate And Plant Sites To Access And Analyze Data.

The Second Phase Of This Project Will Automate The Performance Test And Formulations Data Collection Via Palm Pilots

Confidential Client-ChemicalConfidential Client-ChemicalData Warehouse SystemData Warehouse System

LIMS Has Greatly Improved The Collection LIMS Has Greatly Improved The Collection

And Management Of Laboratory DataAnd Management Of Laboratory Data

Utility Of LIMS Greatly Enhanced When Utility Of LIMS Greatly Enhanced When

Integrated With Other Enterprise SystemsIntegrated With Other Enterprise Systems

Laboratory Systems Integration Results in Laboratory Systems Integration Results in

Improved Quality, Better Customer Service Improved Quality, Better Customer Service

And Decreased CostsAnd Decreased Costs

ConclusionsConclusions

For More Information, contact:

Astrix Technology Group

175 May StreetEdison, NJ 08837732.661.0400www.astrixsoftware.com