laboratory results for acute lymphoblastic leukemia

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  • 7/29/2019 Laboratory Results for Acute Lymphoblastic Leukemia

    1/5

    COMPLETE BLOOD COUNT

    EXAMINATION

    RESULT

    07/16/13

    RESULT

    07/19/13

    RESULT

    07/23/13

    REFERENCE

    VALUE SIGNIFICANCE

    WBC 80.15 42.54 15.79 5-15

    WBC is increased due to leukemi

    a bone marrow disease which

    causes an abnormally high

    production of immature whiteblood cells

    Hemoglobin 43 98 97 120-140

    Hemoglobin is decreased due to

    suppression of the RBC in the

    bone marrow

    Hematocrit 0.14 0.28 0.28 0.36-0.44

    Hemoglobin is decreased due to

    suppression of the RBC in the

    bone marrow

    MCV 87.50 82.60 82.60 73-89 Within normal limits

    MCH 26.90 28.80 29.00 24-30 Within normal limits

    RBC Count 1.60 3.40 3.35 4.10-5.50

    In leukemia, the RBC Count

    decreases because they are

    crowded out of the bone marrow

    by the immature forms of white

    blood cells

    MCHC 327 349 343 320-360 Within normal limits

    RDW 23.90 17.90 18.50 11-16 -

    MPV 9.10 10.00 11.90 6-11 Within normal limits

    Platelet Count39

    17 18 200-400

    In leukemia, the platelet count

    decreases because they are

    crowded out of the bone marrow

    by the early forms of white bloo

    cells

  • 7/29/2019 Laboratory Results for Acute Lymphoblastic Leukemia

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    DIFFERENTIAL COUNT

    EXAMINATION

    RESULT

    07/16/13RESULT

    07/19/13

    RESULT

    07/23/13

    REFERENCE

    VALUE SIGNIFICANCE

    Neutrophil 1.0 1 0 40-74

    Neutrophil production is

    decreased due to inability of the

    bone marrow to produce mature

    white blood cells

    Lymphocytes 12.0 8 20 19-48

    In leukemia, lymphocytes

    decreases because they are

    crowded out of the bone marrow

    by the early forms of white bloo

    cells

    Monocytes 3.0 3.0 0 3-9 -

    Eosinophil 0 0 0 0-7 Within normal limits

    Basophil 0 0 0 0-2 Within normal limits

    Stab 0 0 0 - Within normal limits

    Atypical Lymph 0 0 1 - Within normal limits

    Metamyelocytes 0 0 0 - Within normal limits

    Myelocytes 0 0 0 - Within normal limits

    Blast 84 88 79 - Indicates lymphoblastic

    leukemia

  • 7/29/2019 Laboratory Results for Acute Lymphoblastic Leukemia

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    CHEMISTRY

    EXAMINATION

    RESULT

    07/17/13

    RESULT

    07/22/13

    REFERENCE

    VALUE SIGNIFICANCE

    Creatinine - 0.55 0.9-1.3 Within normal limits

    Uric Acid - 3.16 3.5-7.2 Within normal limits

    Urea - 9.29 8.87-20.55 Within normal limits

    Sodium 136 136 135-148 Within normal limits

    Potassium 4.0 3.70 3.50-5.30 Within normal limits

    Chloride 104 101 90-107 Within normal limits

  • 7/29/2019 Laboratory Results for Acute Lymphoblastic Leukemia

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    URINALYSIS

    07/18/13

    Examination Result Normal Findings Significance

    Color LightYelow Yellow Within normal limits

    Transparency Clear Clear Within normal limits

    Specific Gravity 1.010 1.010 1.030 Within normal limits

    pH 6.5 5.0-7.0 Within normal limits

    Glucose Negative (-) Negative (-) Within normal limits

    Protein Negative (-) Negative (-) Within normal limits

    RBC 0-1 Absent Within normal limits

    WBC0-2 Absent Within normal limits

  • 7/29/2019 Laboratory Results for Acute Lymphoblastic Leukemia

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    05/28/13

    HEMAPATHOLOGIC REPORT

    PERIPHERAL SMEAR

    Smear shows microcytic, hypochromic erythrocytes with wild anisopoikilocytosis. Leukocytes are

    increased in number, consisting predominantly of blast forms. The rest of the WBC population is composed of

    mature lymphocytes. Thrombocytes are slightly decreased in number, showing normal morphology

    Differential Counts

    Blasts: 72%

    Lymphocytes: 28%

    Neutrophils: 1 %

    BONE MARROW SMEAR

    The bone marrow smears are hemodiluted with peripheral blood showing a monotonous population of

    lymphoid precursors, which is predominantly composed of lymphoblast. These cells have small round nuclei,

    noting strict chromatin with inconspicuous nucleoli surrounded by very scant pale blue cytoplasm. There is a

    decrease number in myeloid and erythroid precursors observed. There are no megakaryocytes seen.

    IMPRESSION: Hemodiluted bone marrow smears suggestive of Acute Lymphoblastic Leukemia