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Kyphoplasty for the Kyphoplasty for the Treatment of Treatment of Vertebral Vertebral Compression Compression Fractures Fractures Jessica Brock Jessica Brock Advised by Sam Powdrill Advised by Sam Powdrill

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Page 1: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

Kyphoplasty for the Kyphoplasty for the Treatment of Vertebral Treatment of Vertebral Compression FracturesCompression Fractures

Jessica BrockJessica Brock

Advised by Sam PowdrillAdvised by Sam Powdrill

Page 2: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

Vertebral Compression Vertebral Compression FracturesFractures

The most common complication of The most common complication of osteoporosisosteoporosis

Estimated 700,000 VCFs occur annuallyEstimated 700,000 VCFs occur annually200,000 are refractory to medical management200,000 are refractory to medical management Cost $10-15 billion annuallyCost $10-15 billion annually

Can result in spinal deformity: Can result in spinal deformity: kyphosis/lordosiskyphosis/lordosis

Cause acute and chronic pain leading to Cause acute and chronic pain leading to disabilitydisability

Cause of reduced vital capacityCause of reduced vital capacity

Page 3: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

The Downward SpiralThe Downward Spiral

OsteoporosisOsteoporosis VCFsVCFs Spinal DeformitySpinal Deformity Decreased lung Decreased lung

capacitycapacity Decreased physical Decreased physical

functionfunction Early SatietyEarly Satiety

Sleep problemsSleep problems Decreased activityDecreased activity More bone lossMore bone loss Increased fracture Increased fracture

riskrisk Decreased Decreased

pulmonary functionpulmonary function Increased mortalityIncreased mortality

Page 4: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

PreventionPrevention

Bone Density Testing in women > 65 Bone Density Testing in women > 65 year, men > 70 yearsyear, men > 70 years

Adequate intake of calcium, vitamin Adequate intake of calcium, vitamin D, and regular weight bearing D, and regular weight bearing exerciseexercise

Pharmacology: bisphosphonates, Pharmacology: bisphosphonates, calcitonin, SERMScalcitonin, SERMS

Reduce the risk of fallingReduce the risk of falling

Page 5: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

Signs and SymptomsSigns and Symptoms

Consider VCF in any patient > 50 Consider VCF in any patient > 50 years if they complain of acute or years if they complain of acute or chronic back painchronic back pain

Get a AP and lateral x-ray of the spineGet a AP and lateral x-ray of the spine Look for wedge shaped vertebral Look for wedge shaped vertebral

bodiesbodies MRI with T2 sequence shows state of MRI with T2 sequence shows state of

fracture healingfracture healing

Page 6: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill
Page 7: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

Conservative TherapyConservative Therapy

NSAIDSNSAIDS OpiodsOpiods Muscle relaxantsMuscle relaxants Bed restBed rest Orthotic bracingOrthotic bracing VCF healing should occur in 6-12 VCF healing should occur in 6-12

weeksweeks Refractory in 15-20% of patientsRefractory in 15-20% of patients

Page 8: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

KyphoplastyKyphoplasty

Minimally-invasiveMinimally-invasive PercutaneousPercutaneous Can restore lost vertebral heightCan restore lost vertebral height Immediate pain reductionImmediate pain reduction Fewer complications compared to Fewer complications compared to

vertebroplastyvertebroplasty By 2005, performed on 170,000 By 2005, performed on 170,000

patientspatients

Page 9: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

KyphoplastyKyphoplasty

2 fluoroscopy units for visualization2 fluoroscopy units for visualization Patient is supported in prone positionPatient is supported in prone position 4 cm bilateral incision via the 4 cm bilateral incision via the

pedicles using trocar, guidewire, pedicles using trocar, guidewire, cannula, bone tamp, cementcannula, bone tamp, cement

Maximum of 3 vertebral bodiesMaximum of 3 vertebral bodies

Page 10: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill
Page 11: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill
Page 12: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

ComplicationsComplications

Cement ExtravasationCement Extravasation– Pulmonary embolismPulmonary embolism– AbscessesAbscesses– Disc damageDisc damage

Adjacent VCFs post surgery—20-30%Adjacent VCFs post surgery—20-30% General complication rate 1-2%General complication rate 1-2%

Page 13: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

ConclusionsConclusions

Kyphoplasty is a safe and effective Kyphoplasty is a safe and effective treatment for back pain due to treatment for back pain due to osteoporotic VCFs.osteoporotic VCFs.

Providers should include kyphoplasty Providers should include kyphoplasty in the discussion of options for the in the discussion of options for the VCF patientVCF patient

Reimbursement available by Medicare Reimbursement available by Medicare and private insurance companiesand private insurance companies

Page 14: Kyphoplasty for the Treatment of Vertebral Compression Fractures Jessica Brock Advised by Sam Powdrill

ReferencesReferences ACP medicine, Dale, D, and Federman, D. 3rd edition. WebMD Professional Publishing. ACP medicine, Dale, D, and Federman, D. 3rd edition. WebMD Professional Publishing. New York, NY. 2007, Vol. I, 707-711New York, NY. 2007, Vol. I, 707-711 Albertico, RA. Balloon Kyphoplasty for Multilevel Spinal Metastases from BreastAlbertico, RA. Balloon Kyphoplasty for Multilevel Spinal Metastases from Breast Cancer. J Support Oncol 2007;5:243-246Cancer. J Support Oncol 2007;5:243-246 Garfin, SR, Buckley, RA, and Ledlie, J. Balloon kyphoplasty for symptomatic vertebral Garfin, SR, Buckley, RA, and Ledlie, J. Balloon kyphoplasty for symptomatic vertebral body compression fractures results in rapid, significant, and sustained body compression fractures results in rapid, significant, and sustained improvements in back pain, function, and quality of life for elderly patients. improvements in back pain, function, and quality of life for elderly patients. Spine, 2006. 31(9), p.2213-20.Spine, 2006. 31(9), p.2213-20. Hanna, J, and Letizia, M. A treatment for osteoporotic vertebral compression fractures. Hanna, J, and Letizia, M. A treatment for osteoporotic vertebral compression fractures. Orthopedic Nursing. Vol 26(6). 2007. pg 342-346.Orthopedic Nursing. Vol 26(6). 2007. pg 342-346. Harrison, AL. Changes in the Bone Associated with Aging. Lecture at the University of Harrison, AL. Changes in the Bone Associated with Aging. Lecture at the University of Kentucky. Summer 2007.Kentucky. Summer 2007. Howland, RD, and Mycek MJ. Howland, RD, and Mycek MJ. PharmacologyPharmacology. 3rd edition. Lippincott Williams & . 3rd edition. Lippincott Williams & Wilkins. Philadelphia. 2006.Wilkins. Philadelphia. 2006. Ledlie, JT and Renfro, MB. Kyphoplasty treatment of vertebral fractures: 2-year Ledlie, JT and Renfro, MB. Kyphoplasty treatment of vertebral fractures: 2-year outcomes show sustained benefits. Spine, 2006. 31(1): p.57-64outcomes show sustained benefits. Spine, 2006. 31(1): p.57-64 Pateder, DB, Khanna AJ, and Lieberman, IH. Vertebroplasty and Kyphoplasty for the Pateder, DB, Khanna AJ, and Lieberman, IH. Vertebroplasty and Kyphoplasty for the Management of Osteoporotic Vertebral Compression Fractures. Orthop Clin NManagement of Osteoporotic Vertebral Compression Fractures. Orthop Clin N Am 38 (2007) 409-418.Am 38 (2007) 409-418. Robinson, Y., Tschoke, SK., Stahel, PF, Kayser, R., and Heyde, CE. Complications and Robinson, Y., Tschoke, SK., Stahel, PF, Kayser, R., and Heyde, CE. Complications and safety aspects of kyphoplasty for osteoporotic vertebral fractures: a prospective safety aspects of kyphoplasty for osteoporotic vertebral fractures: a prospective follow-up study in 102 consecutive patients. Patient Safety in Surgery 2008, 2:2.follow-up study in 102 consecutive patients. Patient Safety in Surgery 2008, 2:2. Surgeon General’s Report on Bone Health and Osteoporosis. 2004.Surgeon General’s Report on Bone Health and Osteoporosis. 2004. Taylor, RS, Fritzell, P, and Taylor, RJ. Ballon kyphoplasty in the management of Taylor, RS, Fritzell, P, and Taylor, RJ. Ballon kyphoplasty in the management of vertebral compression fractures: an updated systematic review and meta-analysis. vertebral compression fractures: an updated systematic review and meta-analysis. Eur Spine J (2007) 16:1085-1100.Eur Spine J (2007) 16:1085-1100. Vajnar, J. Compression Fractures in a Man with Osteoporosis. JAAPA Sept 2007, 20(9).Vajnar, J. Compression Fractures in a Man with Osteoporosis. JAAPA Sept 2007, 20(9). Resources:Resources: National Osteoporosis Foundation www.nof.orgNational Osteoporosis Foundation www.nof.org Kyphon, Inc. Sunnydale, CAKyphon, Inc. Sunnydale, CA