KAOSI’S SARCOMA KAOSI’S SARCOMA 18721872

• CHRONIC OR EUROPEAN-CHRONIC OR EUROPEAN- 90% OCCRANCE IN OLD MEN OF EASTERN EUROPEN AS 90% OCCRANCE IN OLD MEN OF EASTERN EUROPEN AS

MULTIPLE PURPLE COLOURED SKIN PLAQUES OR NODULES MULTIPLE PURPLE COLOURED SKIN PLAQUES OR NODULES ASYMPTOMATIC ON LIMBS LOCALISED TO SKIN AND VISCERAS ASYMPTOMATIC ON LIMBS LOCALISED TO SKIN AND VISCERAS INVOLED IN 10% OF CASES WITH LAPSES AND REMISSIONSINVOLED IN 10% OF CASES WITH LAPSES AND REMISSIONS

• LYMPHADENOPATHIC OR LYMPHADENOPATHIC OR AFRICAN/ENDAMICAFRICAN/ENDAMIC – –AMONG YOUNG BANTU AMONG YOUNG BANTU CHILDERN OF SOUTH AFRICA, WITH LOCALISED OR CHILDERN OF SOUTH AFRICA, WITH LOCALISED OR GENERALISED LYMPH ADENOPATHY, EXTREMELY AGGRESSIVE GENERALISED LYMPH ADENOPATHY, EXTREMELY AGGRESSIVE , HIGH PREVELANCE WITH HIV- ASSOCIATED DISEASE, HIGH PREVELANCE WITH HIV- ASSOCIATED DISEASE

• TRANSPLANT ASSOCIATEDTRANSPLANT ASSOCIATED – –AGGRASIVE INVOLVING AGGRASIVE INVOLVING LYMPH NODES MUCOSA & VISCERL ORGEN, REGRESS WHEN LYMPH NODES MUCOSA & VISCERL ORGEN, REGRESS WHEN IMMUNOSUPRESSIVE THERAPY IS REDUCIMMUNOSUPRESSIVE THERAPY IS REDUCEDED

• AIDS ASSOCIATED- IN MALE HOMOSEXUALSAIDS ASSOCIATED- IN MALE HOMOSEXUALS,, DIAGNOSIS MAY PRECED THE CLINICAL RECOGNITION OF DIAGNOSIS MAY PRECED THE CLINICAL RECOGNITION OF AIDS, NO SITE OF PREDILECTION LYMPH NODES , GIT & AIDS, NO SITE OF PREDILECTION LYMPH NODES , GIT & DIASEMINATED FORMDIASEMINATED FORM

KAPOSI’S SARCOMAKAPOSI’S SARCOMA

KAPOSI’S SARCOMAKAPOSI’S SARCOMA

KAPOSI’S SARCOMAKAPOSI’S SARCOMA

KAPOS’S SARCOMAKAPOS’S SARCOMA

KAPOSI’S SARCOMAKAPOSI’S SARCOMAORAL MUCOSAORAL MUCOSA

KAPOSI’S SARCOMAKAPOSI’S SARCOMA

KAPOSI’S SACOMAKAPOSI’S SACOMAHISTOPATHOLOGY X45HISTOPATHOLOGY X45

TREATMANTTREATMANT

-IONIZING RADIATIONS COBALT THERAPY,

ELECTRON BEAM THERAPY

-POLY CHEMOTHERAPY--DOXORUBICIN,

-VINCA ALKALOIDS

-BLEOMYCINE

-INTERFON-ALFA,

-HAART