Juvenile Macular Degeneration

Lauran Maestas

Meghan Raney

Cressie Wright

Three major forms of Juvenile Macular Degeneration

Best’s Disease Juvenile Retinoschisis Stargardt Disease

All are rare and cause central vision loss

Stargardt Disease First report in 1901 German Ophthalmologist Karl Stargardt 1997 genetic component discovered

Recessive gene Both parents must have

Stargardt GeneStargardt No protein produced Without protein no energy No energy photoreceptor

cells in retina degenerates

Normal Gene produces

protein Protein produces

energy Energy sent to the

photoreceptor cells

Effects of gene defect Fatty yellow pigment (Lipofusion)

Build up under cells in macula Rods and Cones are affected Atrophy in the macula Loss of central vision Blindness

Symptoms Visual Acuity

20/40 20/200 Central Vision Loss Vision Acuity Blurry Vision Distorted Vision

Symptoms Dark Areas Color Perceptions Central Scotoma

(Blind Spot in Central Vision)

Night Blindness Photophobia

(Abnormal tolerance for light)

Treatments No Cure Current research:

UV Protective glasses may slow the progression Limit intake of vitamin A Stem cells in adult body fat

References

Stargardt Disease. (n.d.). American Macular Degeneration Foundation |. Retrieved July 11, 2014, from https://www.macular.org/stargardt-disease

Stargardt macular degeneration. (2014, July 7). Genetics Home Reference. Retrieved July 11, 2014, from http://ghr.nlm.nih.gov/condition/stargardt-macular-degeneration

Kinkade, D. R. (2012, November 6). Low Vision Eyeglasses LowVisionEyeglasses.com: Guide to Macular Degeneration: Short Answers to Complex Questions. Low Vision Eyeglasses LowVisionEyeglasses.com: Guide to Macular Degeneration: Short Answers to Complex Questions. Retrieved July 11, 2014, from http://lowvisioneyeglasses.blogspot.com/2012/11/guide-to-macular-degeneration-short.html

Stargardt Disease. (2014, November 7). . Retrieved July 11, 2014, from http://www.retina-international.org/eye-conditions/retinal-degenerative-conditions/stargardt

Grossman, M. (2013, August 28). Stem Cells Discovered in Fat May Treat Macular Disgeneration, Retinitis Pigmentosa, Stargardt's. Eye conditions, eye care & diseases, treatment solutions. Retrieved July 11, 2014, from http://www.naturaleyecare.com/blog/stem-cells-fat/

Grossman, M. (n.d.). Stargardt's Disease. Eye Care. Retrieved July 11, 2014, from http://www.naturaleyecare.com/eye-conditions/stargardts/

Age-Related Macular Degeneration (AMD)

Lauran Maestas

Meghan Raney

Cressie Wright

What is Age-Related Macular Degeneration (AMD)?

AMD is a condition that causes central vision loss

AMD is the leading cause of vision loss for people over the age of 60

Two Forms of AMD Dry Age-Related Macular Degeneration

More common Develops slowly

Wet Age-Related Macular Degeneration More severe Develops quickly

Causes of AMD?

Causes are unknown but possible risk factors include:

• Smoking• Obesity• Poor Diet• Exposure to UV

light

• High Cholesterol• Hypertension• Hereditary• Race• Gender

Symptoms of AMD

Blurriness Wavy Lines Blind Spot

http://www.preservision.com/en/what-is-amd/visionsimulator/

Dry AMD Usually affects both eyes Light Sensitive cells in the macula begin to

breakdown and die Presents of Drusen

yellow spots under the retina Photograph of a healthy eye

Photograph of an eye with dry AMD

Wet AMD Abnormal blood vessel growth Blood and fluid leak under the macula Leads to scarring

Photograph of a healthy eye

Photograph of an eye with wet AMD

TreatmentsDry AMD No cure or treatments Vitamins

Some studies show specific combinations of vitamins can slow the progression and impact

Wet AMD

No cure Treatments

Injections into the eye

Photodynamic Therapy

Laser Therapy

Tools to Detect Progression of AMD The Amsler Grid is a simple test to detect

early signs of AMD Demonstration of Reduced Visual Acuity

http://www.lucentis.com/get-support

Case Study: Ernest Smith Age-Related Macular Degeneration Advanced Wet AMD in OS Caused by oxidative stress Used optical coherence tomography test Treatment available: Thermal Laser Therapy Daily monitor: Amsler Grid Had to have treatment again

ReferencesAbout wet AMD. (n.d.). What is Wet AMD. Retrieved July 15, 2014, from

http://www.lucentis.com/information/wet-age-related-macular-degeneration

Boyd, K. (2013, September 1). What Is Age-Related Macular Degeneration?. - Eye M.D.-approved information from EyeSmart. Retrieved July 15, 2014, from http://www.geteyesmart.org/eyesmart/diseases/age-related-macular-degeneration/index.cfm

Wet macular degeneration. (n.d.). Definition. Retrieved July 15, 2014, from http://www.mayoclinic.org/diseases-conditions/wet-macular-degeneration/basics/definition/con-20043518

What is Age-Related Macular Degeneration (AMD)?. (n.d.). Bausch + Lomb. Retrieved July 15, 2014, from http://www.preservision.com/en/what-is-amd/what-is-amd/

WHAT IS AMD?. (n.d.). What is Age-Related Macular Degeneration?. Retrieved July 15, 2014, from http://www.amdawareness.org/asrs/what-is-amd