just a biopsy sara is 19 yrs old girl, presented to the hospital with history of progressive sob,...

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Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea occurs with minimal exertion and and associated with orthopnea. Cough is productive of yellowish sputum with occasional

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Page 1: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Just a Biopsy

Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks.

Dyspnoea occurs with minimal exertion and and associated with orthopnea.

Cough is productive of yellowish sputum with occasional hemoptysis.

Page 2: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Week before admission she started to have dysphagia.

She was admitted to Medical ward on 25/12/1427 for further investigations and management.

Routine investigations were done.

CXR showed huge mediastinal mass

Page 3: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 4: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 5: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Then, The patient was booked for urgent chest CT scan and CT guided biopsy but procedure was cancelled because the patient can not lie down (flat on the bed).

CT done in (semi) lateral position.

Page 6: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 7: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 8: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Pleural tap was done and there was no evidence of malignant cell.

Mediastinoscopic biopsy was taken But the result was not informative and TRUE CUT biopsy was suggested To reach the diagnosis.

On 5/1/28 the patient was booked for emergency mini thoracotomy and true cut Biopsy.

Page 9: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Preoperative Anesthetic Assessment

History: Clinical Examination: She was looking fair. Conciuos,alert and oreinted. She can lie comfortable only on right

lateral position. She was afebrile, with normal vital

signs. RR 18, HR 80 , BP 110/60, Spo2 98% on

RA.

Page 10: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..PreOperative Anesthetic Assessment

CVS: NAD Resp: Good air entry Bilatrally with

harsh breath sounds. A.W: Mallampati 1, TMD >6.5cm She has dilated Neck Veins and

over the right side of the chest (SVC obstruction).

Page 11: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..PreOperative Anesthetic Assessment

Biochemical analysis, normal

PFT: was done but the patient was not able to do it Properly.

Pred

Pre Pre/Pred

FVC 3.58

.95 26.7

FEV1

3.21

.81 25.1

FEV1/%fvc

89.2

84.3

94.5

PEF 6.96

2.07

29.8

Page 12: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..PreOperative Anesthetic Assessment

Preoperative Orders

ECG,ABG were Requested. High Risk Consent. ICU bed.

Page 13: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..PreOperative Anesthetic Assessment

ECG : Right Axis Deviaton. ABG : Normal. MICU bed was Available. So the patient was taken for the

O.R. on Wednesday 5/2/1428.

Page 14: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

IntraOperative Course

Induction Routine monitors were attached. 18 G cannula was inserted. Inhalational induction with

Sevoflurane 8% with O2 while the patient in semi sitting position.

Sedating dose of propofol was used 40mg plus 50 mcg of fentanyl.

Page 15: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..IntraOperative Course

Lidocaine 10% was sprayed on the base of the tongue and Pharynx.

2ml of 2%lidocaine was injected intratracheal.

By ordinary laryngoscope patient was intubated with 7.0 ETT, smooth intubation.

Another dose of fentanyl 50mcg was given.

Page 16: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..IntraOperative Course

Then the patient was kept spontaneously Breathing with some assistance manually as needed.

A.W pressure was high during manual assistance of ventialtion, because the patient was almost flat during Surgical Procedure.

Page 17: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..IntraOperative Course

The Procedure lasted almost 40 minutes during which the patient was hemodynamiclly stable.

SpO2 98-99%, EtCO2 60-85. Multiple Biopsies were taken After

aspiration from Anterior Mediastinal mass Through the left 2nd Intercostal Space and left ICT was inserted.

Page 18: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..IntraOperative Course

Intraoperative Bronchoscopy was done which showed external compression on trachea and bronchi.

Page 19: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 20: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..IntraOperative Course

At the end of The Procedure The patient was given A chance of Extubation But She did not gain consciousness and maintain good ventilatory parameter. So she was

Re Intubated and kept spontaneously breathing with CPAP and was transferred to MICU.

Page 21: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

PostOperative Course

In MICU the patient was kept Intubated sedated and Ventilated for 7days.

In the first day she developed High Airway Pressure and desaturation which was solved by Changing the patient Positioning…(Positioning!)

PCV: FiO2 0.4, P:20Tv:600+ , R18.

Page 22: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..PostOperative Course

On 6/1/28 the result of the Biopsy was revealed As:

NON-HODGKIN LYMPHOMAB-CELL TYPE.

Same day Chemotherapy was started.

On 9/1/28 , Bronchoscopy was done which showed external compression at carina almost complete during Expiration.

Page 23: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 24: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Cont..PostOperative Course

Five days after Chemotherapy the patint was extubated - (12/1/28). And she was kept for Four days in MICU.

On 16/12/28 the patient was discharged from MICU to the medical ward and She was able to lie flat without any respiratory compromise.

On 17/1/28, CT scan of the chest was repeated.

Page 25: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 26: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 27: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea
Page 28: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

On 29/1/28 , the patient was discharged from the hospital with home medicines and appointments For investigations and follow up for further Chemotherapy cycles.

Page 29: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Before ChemoRx After ChemoRx

Page 30: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea

Before ChemoRx After ChemoRx

Page 31: Just a Biopsy Sara is 19 yrs old girl, Presented to the hospital with history of Progressive SOB, cough weight loss and fatigability for 6 weeks. Dyspnoea