AgBiomeBIO World Congress

July 9th, 2019

CONFIDENTIAL2Source: Worldometers, UN World Population Prospects

POPULATION REACHING NEW HEIGHTS

IN BILLIONS11.2B

As economies get wealthier,

protein demand increases

CONFIDENTIAL3

FOOD INSECURITY ALREADY A MAJOR ISSUE

Leading to Social InstabilityUndernourished People in the World

821M

Source: FAO, Undernourished are those facing chronic food deprivation.

“The Arab Spring was a revolution of the hungry”

- Boston Globe

CONFIDENTIAL

BASIC CONSTRAINTS FOR FOOD PRODUCTION

4

We need 70% increase in food production by 2050. 2x by 2100

Water

10%

30%Land area on earth

~15B hectares

Available land for food, feed and fiber production~1.5B hectares

2.5% fresh water

<1% is usable

Source: IAEA, FAO

CONFIDENTIAL

DEVASTATING IMPACT OF PESTS AND DISEASE

5Source: Blue River Technology

We lose >20% of crops each year, up to 100% if unprotected

Rapid Spread of Emerging Diseases Resistance to Old Chemicals

Nontreated100% loss

Fungicide treated100% harvested

Powdery Mildew Fungus

CONFIDENTIAL

AGBIOME: LEADING AG INNOVATOR

6

Most advancedand growing pipeline

of traits and biologicalstargeting large markets

Novel microbiome-

based discovery platform to

develop new products

Fastest paceof discovery andtime to market

INVESTORS

InnotechAdvisors

GENESIS™ TECHNOLOGY

7

TrillionsMICROBES

Largest SequencedMicrobe Collection

65,000+

Database Tracks Location, Genome Sequence, Bioassay,

and Field Results

Fully-integrated Systematic, Data-Driven Screening

Process

10,000sStrains

100sGreenhouse

Leads

BIOLOGICALS

DozensFieldLeads

MillionsSingleGenes

1,000sGene

CandidatesTRAITS

Continuous Improvement and Dramatic IP Expansion

CONFIDENTIAL8

Less than 4 years from lab to EPA registered product

• Active on multiple diseases• Organic (OMRI) listed• Pre and post harvest solution

ControlHowler Chemical

>20x MoreEFFECTIVE THAN

CURRENT BIOLOGICALS

COMPARABLETO CHEMICAL

REVOLUTIONARY PRODUCTS: HOWLER™/ZIO™

• Adds to Product Portfolio• Spore-forming microbe, increased formulation

options• Complementary activity increases best-in-industry

efficacy against key disease targets

Complements and Expands Portfolio

Theia™Inoculated CheckHowler™

9

Theia™

CONFIDENTIAL

OPPORTUNITIES FOR SYNTHETIC BIOLOGY IN CROP PROTECTION

10

Improving yield by increasing crop efficiency and production:• Improve photosynthesis efficiency• Improve soil nutrients, water, and CO2 use efficiency• Increase nitrogen fixation by host engineering or microbiome

Maintaining crop yields under abiotic stress:• Minimize change in crop development times expected under higher

temperatures• Reduce heat- and water-stress-response during critical reproductive periods• Reduce transpiration in high temperatures

Maintaining crop yield under biotic stress:• Native or insect or disease resistant traits• Transgenic or wild relatives insect or disease traits• Microbiome engineering

Biosensors

CONFIDENTIAL

MICROBIALDEVELOPMENT PLATFORM

TERRA™Database

MachineLearning

Microbe Collection

EXPANDING OUR FOCUS

11

AGRICULTURE

ANIMAL HEALTH

HUMAN HEALTH

LifeEDIT™

CONFIDENTIAL12

Feed the world, responsibly.

Partner with the microbial world for human benefit.