Biomedical Imaging: Engineering Leadership

Joseph A. O’Sullivan, PhDElectrical & Systems Engineering

Director, Electronic Systems & Signals Research Laboratory

Associate Director, Center for Security Technologies

Chair, Faculty Senate

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Imaging Activities4 Imaging Fundamentals to Applications4 Fundamentals 4Data modeling, random processes4Optimization, algorithm development4 Implementations4 Imaging Science and Engineering Program

4Applications4Military imaging: radar, infrared, optical, target recognition (ESSRL, CST)4Industrial: computer vision, biometrics (CST)4Medical: X-ray CT, PET (ESSRL, Radiology)

Interdisciplinary Biomedical Imaging4Positron Emission Tomography: Michel Ter-Pogossian, Marc Raichle, Don Snyder, Jerry Cox, Mike Phelps, Mike Welch, others

Interdisciplinary Biomedical Imaging4 Positron Emission Tomography: Michel Ter-Pogossian, Marc

Raichle, Don Snyder, Jerry Cox, Mike Phelps, Mike Welch, others

4 Gamma Ray Cameras: Jerry Cox, Ken Larson, J. Eichling, B. Siegel

4 Maximum likelihood imaging for PET: Don Snyder, Mike Miller, Tom Miller, Lew Thomas, Jerry Cox

4 Computational Imaging for SPECT: D. Snyder, M. Miller, T. Miller

4 Computational Deformable Anatomy: Mike Miller, Don Snyder, David Van Essen, graduate students

4 Computational Microscopy: Don Snyder, Chrysanthe Preza, Jose Conchello, Jeff McNally

4 X-ray Computed Tomography with Metal: Don Snyder, Jody O’Sullivan, Jim Blaine, Jeff Williamson, Bruce Whiting, Dave Politte

4 Optical Diffusion Tomography: John Schotland

Biomedical Imaging: X-ray Computed Tomography

Imaging in the presence of metal4Cervical cancer (brachytherapy)

NCI J. Williamson, PI, J. A. O’Sullivan,D. L. Snyder, B. Whiting, D. G. Politte

4Cochlear implantsWhitaker B. Whiting, PI; M. Skinner

4Artificial joints, dental implants4Micro-CT4 PET/CT Machines4 Impact on luggage inspection (CST)

Biomedical Imaging: PET/CT Machines

4 PET/CT Machines4 CT images used for

attenuation correction 4 Streaking artifacts propagate4 New proposal to NIBIB

J. A. O’Sullivan, PI, D. L. Snyder, B. Whiting, M. Mintun, R. Laforest, D. G. Politte, G. J. Blaine

PET/CT Artifacts:Data from M. Mintun and R. Laforest

Dental implantsin PET/CT

Artificial hipin PET/CT

Barium Artifacts: Data from M. Mintun and R. Laforest

Attenuation Corrected Not Attenuation Corrected

Interdisciplinary Biomedical Imaging

4World Leadership4Interdisciplinary aspect key

4SEAS—WUSM Collaborations4Strong historical foundations4Exciting future

4New Project: CT and PET PET/CT