jonnesco's method of spinal anaesthesia

1
1152 Almost all the trained mountaineers are unfavourable to the use of alcohol in any form or at any time on the mountain, one notable exception being Mr. W. B. Coolidge. But even he only says that a small quantity of wine is a better resto- rative than tea or coffee and that cognac is indispensable as a reserve in case of exhaustion. Mr. Coolidge is an accom- plished mountaineer and not a medical man, but his experience agrees closely with that given by Mr. Clinton T. Dent, who rarely takes alcohol with him, but says that the chief value of alcohol lies in its stimulating- power to the .appetite. ’’ Let the man who can eat without alcohol not use it ! But in the case of one who has no desire for food alcohol can stimulate that desire; and, what is more important, improve the power of assimilation at the same. time." This action of alcohol was noticed in particular, we remember, during the Ashanti war of 1874. It was then found that alcohol on the march, though it gave rise to temporary stimulation, yet produced greater fatigue after the stimulation had passed off. On reaching camp at night the older men found that a small ration of rum increased their appetite and made it possible for them to enjoy their food. Beef tea was found to be a better stimulant for marching than alcohol, while it was not followed by secondary depression. Dr. Schnyder comes to the conclusion that alcohol is harmful during the climb, that it may be used to enable the climber to overcome the last obstacle as a final stimulus, and that it is useful as an aid to appetite and digestion. He suggests as a substitute for alcohol some substance con- taining caffeine, and has devised the following powder : kola and cocoa of each 5 grammes ; sugar, 10 grammes; to be taken in a little water. - JONNESCO’S METHOD OF SPINAL ANAESTHESIA. Professor Thomas Jonnesco has been visiting the principal European capitals and America to demonstrate his views. In reporting his demonstration in London we stated that the results did not bear out all his claims, for in two out of the three cases the anaesthesia was far from satisfactory. However, it was thought possible that this was due to the fact that the stovaine was sterilised, which is contrary to Professor Jonnesco’s directions. In the Montreal Medical Journal for February Dr. W. W. Chapman reports a demonstration given by Professor Jonnesco at the Mount Sinai Hospital, New York, which confirms our criticisms. The operating theatre, it seems, was crowded by the New York profession. Professor Jonnesco was accom- panied by his own assistant, who carried an ordinary Pravaz exploring syringe with a needle about 4 inches long, and two sealed bottles of strychnine solution of different strengths, a tube of stovaine crystals, and mixing tube. In the first case a man, aged 25 years, had his right breast removed for chrenic mastitis. The patient was placed in the sitting posture with the chin flexed on the sternum. Having sterilised the skin and prepared the solution, Professor Jonnesco plunged the needle between the first two dorsal vertebrate to a depth of 3 inches, but no cerebro-spinal fluid appeared, even after aspiration, only blood. The needle was withdrawn and introduced a second time. Aspiration again yielded only blood, but afterwards a drop of clear fluid appeared and the solution was injected. After ten minutes the incision was made. The patient bitterly complained of the pain and begged for ether. Encouraged by the surgeon he allowed the operation to be completed. He afterwards shated that he felt every cut but one. An operation for inguinal hernia was performed under satisfactory anaesthesia, but after the operation the face was pale and there was some sweating. In a case of operation for tuberculous cervical 1 THE LANCET, Nov. 27th, 1909, p. 1607. glands upper dorsal puncture was performed, but after three attempts the spinal canal could not be found and spinal anaesthesia was abandoned. In an operation for appendicitis the anaesthesia was satisfactory, but the patient almost at once began to complain of headache. It is note- worthy that Professor Jonnesco considered the anesthesia in the first case satisfactory. This appears to show that his success may be partly due to the fact that his Roumanian patients are more stolid than those in English-speaking countries. His other claim for his method-perfect safety- also requires more support. In the Indian Medical Gazette for February the death is reported of a native, aged 41 years, who was anæsthetised for removal of a large elephantiasis of the scrotum. The patient seemed to be in good health otherwise, though he was very stout. Three cubic centimetres of distilled water containing 1 milligramme of strychnine hydrochloride and 1 decigramme of novocaine were injected between the last two dorsal vertebras and ana3sthesia was rapidly induced. During the operation the patient com- plained of difficulty of breathing, which was attributed to the weight of the tumour which was turned up on the abdomen. When the operation was almost completed and the pedicle about to be severed respiration stopped and all attempts at resuscitation failed. In performing artificial respiration it. was noticed that the arms were rigid. This was thought to indicate that death was due to the action of the strychnine on the medulla. A death has also been reported from the General Hospital, Birmingham. THE CENTENARY OF BENEDIKT STILLING’S BIRTH. ON Feb. 22nd, 1810, Benedikt Stilling was born at Kirchhain, near Marburg, of Jewish parents. In memory of the centenary of his birth the Münchener Medizinische Wochenschrift of March 29th publishes a brief notice of his career, together with his portrait. According to Dr. L. Strauss of Biebrich, who contributes his memorial notice, the remarkable researches of this great worker, whom Kussmaul described as " the pioneer and Columbus of a new world," have not received sufficient recognition even in Germany, although his name survives in the sacral nucleus of Stilling of the spinal cord. He was educated in the Gymnasium at Marburg and graduated in the university of the same town, shortly afterwards being appointed provincial surgeon at Cassel. Here he appears to have obtained distinction as an operating surgeon and soon to have acquired an European reputation. In spite of the demands made upon him by a very large practice, he was assiduous in research, for, as he himself said, there glowed hot within him the desire for scientific knowledge. His best known work is that dealing with the structure of the brain and spinal cord, at which he worked for nearly 40 years. He was the first to prepare complete serial sections and to trace groups of fibres in the nervous system by this means. He also demonstrated the cranial nerve nuclei situated between the corpora quadrigemina and the medulla oblongata, and in particular he described the nuclei of the hypoglossal, the vagus, and the facial nerves, the motor nucleus of the fifth, the nuclei of the fourth and the third nerves, and the upper nucleus of the spinal accessory. He established by experiment the nature of the vaso-motor mechanism and its relation to the sympathetic system. He also showed that an active dilatation of the blood-vessels as well as an active contraction occurred. His observa. tions on conduction in the spinal cord were for the most part confirmed by later observers. Great as were Stilling’s contributions to scientific medicine he did not neglect the practical side. He was one of the early ovariotomists, performing his first operation of that kind in 1837. He

Upload: trantruc

Post on 30-Dec-2016

214 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: JONNESCO'S METHOD OF SPINAL ANAESTHESIA

1152

Almost all the trained mountaineers are unfavourable to theuse of alcohol in any form or at any time on the mountain,one notable exception being Mr. W. B. Coolidge. But even

he only says that a small quantity of wine is a better resto-rative than tea or coffee and that cognac is indispensable as areserve in case of exhaustion. Mr. Coolidge is an accom-plished mountaineer and not a medical man, but his

experience agrees closely with that given by Mr. ClintonT. Dent, who rarely takes alcohol with him, but says that thechief value of alcohol lies in its stimulating- power to the.appetite. ’’ Let the man who can eat without alcohol notuse it ! But in the case of one who has no desire for foodalcohol can stimulate that desire; and, what is more

important, improve the power of assimilation at the same.time." This action of alcohol was noticed in particular, weremember, during the Ashanti war of 1874. It was then

found that alcohol on the march, though it gave rise to

temporary stimulation, yet produced greater fatigue after thestimulation had passed off. On reaching camp at night theolder men found that a small ration of rum increased their

appetite and made it possible for them to enjoy their food.Beef tea was found to be a better stimulant for marchingthan alcohol, while it was not followed by secondarydepression. Dr. Schnyder comes to the conclusion that alcoholis harmful during the climb, that it may be used to enablethe climber to overcome the last obstacle as a final stimulus,and that it is useful as an aid to appetite and digestion.He suggests as a substitute for alcohol some substance con-taining caffeine, and has devised the following powder :kola and cocoa of each 5 grammes ; sugar, 10 grammes; tobe taken in a little water.

-

JONNESCO’S METHOD OF SPINAL ANAESTHESIA.

Professor Thomas Jonnesco has been visiting the principalEuropean capitals and America to demonstrate his

views. In reporting his demonstration in London westated that the results did not bear out all his claims,for in two out of the three cases the anaesthesia was farfrom satisfactory. However, it was thought possible thatthis was due to the fact that the stovaine was sterilised,which is contrary to Professor Jonnesco’s directions. In the

Montreal Medical Journal for February Dr. W. W. Chapmanreports a demonstration given by Professor Jonnesco at theMount Sinai Hospital, New York, which confirms our

criticisms. The operating theatre, it seems, was crowded bythe New York profession. Professor Jonnesco was accom-

panied by his own assistant, who carried an ordinary Pravazexploring syringe with a needle about 4 inches long, and twosealed bottles of strychnine solution of different strengths, atube of stovaine crystals, and mixing tube. In the first

case a man, aged 25 years, had his right breast removed forchrenic mastitis. The patient was placed in the sittingposture with the chin flexed on the sternum. Havingsterilised the skin and prepared the solution, ProfessorJonnesco plunged the needle between the first two dorsalvertebrate to a depth of 3 inches, but no cerebro-spinal fluidappeared, even after aspiration, only blood. The needle waswithdrawn and introduced a second time. Aspiration againyielded only blood, but afterwards a drop of clear fluid

appeared and the solution was injected. After ten minutesthe incision was made. The patient bitterly complained ofthe pain and begged for ether. Encouraged by the surgeonhe allowed the operation to be completed. He afterwardsshated that he felt every cut but one. An operation for

inguinal hernia was performed under satisfactory anaesthesia,but after the operation the face was pale and there was somesweating. In a case of operation for tuberculous cervical

1 THE LANCET, Nov. 27th, 1909, p. 1607.

glands upper dorsal puncture was performed, but after

three attempts the spinal canal could not be found and

spinal anaesthesia was abandoned. In an operation for

appendicitis the anaesthesia was satisfactory, but the patientalmost at once began to complain of headache. It is note-

worthy that Professor Jonnesco considered the anesthesia inthe first case satisfactory. This appears to show that hissuccess may be partly due to the fact that his Roumanian

patients are more stolid than those in English-speakingcountries. His other claim for his method-perfect safety-also requires more support. In the Indian Medical Gazette forFebruary the death is reported of a native, aged 41 years,who was anæsthetised for removal of a large elephantiasis ofthe scrotum. The patient seemed to be in good healthotherwise, though he was very stout. Three cubic centimetresof distilled water containing 1 milligramme of strychninehydrochloride and 1 decigramme of novocaine were injectedbetween the last two dorsal vertebras and ana3sthesia was

rapidly induced. During the operation the patient com-plained of difficulty of breathing, which was attributed tothe weight of the tumour which was turned up on the

abdomen. When the operation was almost completed andthe pedicle about to be severed respiration stopped and allattempts at resuscitation failed. In performing artificial

respiration it. was noticed that the arms were rigid. Thiswas thought to indicate that death was due to the actionof the strychnine on the medulla. A death has also been

reported from the General Hospital, Birmingham.

THE CENTENARY OF BENEDIKT STILLING’SBIRTH.

ON Feb. 22nd, 1810, Benedikt Stilling was born at

Kirchhain, near Marburg, of Jewish parents. In memory ofthe centenary of his birth the Münchener Medizinische

Wochenschrift of March 29th publishes a brief notice of hiscareer, together with his portrait. According to Dr. L.

Strauss of Biebrich, who contributes his memorial notice,the remarkable researches of this great worker, whom

Kussmaul described as " the pioneer and Columbus of a newworld," have not received sufficient recognition even in

Germany, although his name survives in the sacral nucleusof Stilling of the spinal cord. He was educated in the

Gymnasium at Marburg and graduated in the university ofthe same town, shortly afterwards being appointed provincialsurgeon at Cassel. Here he appears to have obtaineddistinction as an operating surgeon and soon to have

acquired an European reputation. In spite of thedemands made upon him by a very large practice,he was assiduous in research, for, as he himself said,there glowed hot within him the desire for scientific

knowledge. His best known work is that dealing with thestructure of the brain and spinal cord, at which he workedfor nearly 40 years. He was the first to prepare completeserial sections and to trace groups of fibres in the nervous

system by this means. He also demonstrated the cranialnerve nuclei situated between the corpora quadrigemina andthe medulla oblongata, and in particular he described thenuclei of the hypoglossal, the vagus, and the facial nerves, themotor nucleus of the fifth, the nuclei of the fourth and thethird nerves, and the upper nucleus of the spinal accessory.He established by experiment the nature of the vaso-motormechanism and its relation to the sympathetic system. He

also showed that an active dilatation of the blood-vessels aswell as an active contraction occurred. His observa.tions on conduction in the spinal cord were for the most

part confirmed by later observers. Great as were Stilling’scontributions to scientific medicine he did not neglectthe practical side. He was one of the early ovariotomists,performing his first operation of that kind in 1837. He