ivf hyperresponders
TRANSCRIPT
02.12.2016
1
IVF- hyperresponders
Dr. Tevfik Yoldemir
Marmara Üniversitesi Kadın Hastalıkları ve Doğum A.D.
Over rezerv parametreleri
European Journal of Obstetrics & Gynecology
and Reproductive Biology 168 (2013) 173–177
02.12.2016
2
GnRH antagonist rescue
Reproductive BioMedicine Online (2012) 25, 284– 291
GnRH antagonist rescue
Reproductive BioMedicine Online (2012) 25, 284– 291
02.12.2016
3
Reproductive BioMedicine Online (2012) 25, 284– 291
Mild Anta vs Long Agon.
J Assist Reprod Genet (2012) 29:1343–1351
Mild – 150 IU CD4, GnRHanta CD8
02.12.2016
4
D3 ET vs Blast transfer
J Assist Reprod Genet (2014) 31:275–278
Blast transfer vs FET
J Assist Reprod Genet (2014) 31:275–278
02.12.2016
5
Prognostik faktörler - GnRHAnta
Human Reproduction, Vol.29, No.8 pp. 1688–1697, 2014
Over cevabı- gonadotropin tipi
Gynecol Endocrinol, 2014; 30(6): 444–450
02.12.2016
6
Canlı doğum- gonadotropin tipi
Gynecol Endocrinol, 2014; 30(6): 444–450
Papanikolaou et al. Reproductive Biology and Endocrinology 2011, 9:147
02.12.2016
7
Reproductive Biology and Endocrinology 2011, 9:85
Stimulasyon tahmini
Reproductive Biology and Endocrinology 2007, 5:9 doi:10.1186/1477-7827-5-9
02.12.2016
8
IVFde Yüksek cevap
Reproductive Biology and Endocrinology 2007, 5:9 doi:10.1186/1477-7827-5-9
Bireyselleştirilmiş tedavi
Human Reproduction Update, Vol.20, No.1 pp. 124–140, 2014
02.12.2016
9
AMH cut-off değerleri – yuksek cevap
Human Reproduction Update, Vol.20, No.1 pp. 124–140, 2014
AFS cut-off değerleri – yüksek cevap
Human Reproduction Update, Vol.20, No.1 pp. 124–140, 2014
02.12.2016
10
Tedavi stratejisi
Human Reproduction Update, Vol.20, No.1 pp. 124–140, 2014
Bireyselleştirilmiş AMH bazlı KOS
Nelson 2009 Yates 2011
02.12.2016
11
FSH başlangıç dozu –yaş, AFS,FSHD3
La Marca 2013
FSH başlangıç dozu –yaş, AMH,FSHD3
La Marca 2012
02.12.2016
12
Anta vs Agonist – iyi prognozlu hastalar
Reproductive BioMedicine Online (2014) 29, 299–304
Anta vs Agonist – iyi prognozlu hastalar
Reproductive BioMedicine Online (2014) 29, 299–304
02.12.2016
13
Anta vs Agonist – iyi prognozlu hastalar
Reproductive BioMedicine Online (2014) 29, 299–304
Progesteron yüksekliği taze ET
Gebelik - PE olanlar vs PE olmayanlar
Human Reproduction Update, Vol.19, No.5 pp. 433–457, 2013
02.12.2016
14
Gebelik PE olanlar vs PE olmayanlar
Alt grup analizi
Human Reproduction Update, Vol.19, No.5 pp. 433–457, 2013
Gebelik - PE olanlar vs PE olmayanlar
Alt grup analizi
Human Reproduction Update, Vol.19, No.5 pp. 433–457, 2013
02.12.2016
15
Gebelik - PE olanlar vs PE olmayanlar
Human Reproduction Update, Vol.19, No.5 pp. 433–457, 2013
GnRHanta trigger
Human Reproduction Update, Vol.17, No.4 pp. 510–524, 201120 / 200
02.12.2016
16
Foliküllerin seyri
Human Reproduction Update, Vol.15, No.1 pp. 13–29, 2009
FSH penceresi
Human Reproduction Update, Vol.15, No.1 pp. 13–29, 2009
02.12.2016
17
Oosit ve embryo –
konvansiyonel vs mild
Human Reproduction Update, Vol.15, No.1 pp. 13–29, 2009
Natural siklus IVF
Human Reproduction Update, Vol.15, No.1 pp. 13–29, 2009
02.12.2016
18
KS ile IVF
Human Reproduction Update, Vol.15, No.1 pp. 13–29, 2009
Geç başlangıçlı IVF
Human Reproduction Update, Vol.15, No.1 pp. 13–29, 2009
02.12.2016
19
AFS AMH – yüksek cevap
Human Reproduction Update, Vol.17, No.1 pp. 46–54, 2011
Yüksek AMH – Düşük AMH
.Fertility and Sterility® Vol. 102, No. 6, December 2014
5.2 μg, 6.9 μ g, 8.6 μg, 10.3 μ g, or 12.1 μg rhFSH (FE 999049; Ferring Pharmaceuticals),
11 μg (150 IU) follitropin alfa (Gonal-F filled by mass; Merck Serono).
02.12.2016
20
Yüksek AMH – Düşük AMH
Fertility and Sterility® Vol. 102, No. 6, December 2014
Yüksek AMH – Düşük AMH
Fertility and Sterility® Vol. 102, No. 6, December 2014
02.12.2016
21
Yüksek AMH – Düşük AMH