Issues in developing NDAR autism ontology

Samson TuStanford Center for Biomedical Informatics Research

2007-11-19 conference call

Strategies for extending BIRLEX ontology

Define concepts derived from literatureDSM-IV concepts (capabilities)Hus 2007 concepts (phenotypes)

Model assessment resultsNDAR codebook

Relate concepts to assessment results using OWL DL or SWRL rules

Model CodeBook as assessment result

Issues in using BIRNLex

Versions and inconsistencies Clarification of concepts

Phenotype under _birnlex limbo classPhenotype/behavior/developmental

capability/, assessment/assessed results/assessment instrument

Distinction between generically and specifically-dependent classes

Need for community input

BIRN Mediator issues

Current definitions written in OWL DL or SWRL

Develop user-level tools Translation to BIRN Mediator?

Need BIRN Mediator query language Need to understand how ontology is used

Low repetitive sensory motor activity adi_2003((?a) ∧dbaes_unsensfailC4(?a, ?rsma1) ∧cbaes_unsensfailC4(?a, ?rsma2) ∧intbehav_cunsens(?a, ?rsma3) ∧intbehav_eunsens(?a, ?rsma4) ∧intbehav_cabinr(?a, ?rsma5) ∧intbehav_eabinr(?a, ?rsma6) ∧swrlb:add(?sum, ?rsma1, ?rsma2, ?rsma3, ?rsma4, ?rsma5, ?rsma6) ∧swrlb:lessThanOrEqual(?sum, 4) → LRSMA(?a)