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Welcome Message from the ISR President Dr Sandy Fraser

Dear Colleagues and Friends

I have great pleasure in welcoming you all to The Rochestown Park Hotel Cork for thisyear’s ISR Spring Meeting. This will be the first meeting for me in my new role asPresident of the ISR so I would be delighted to gather your views during the meeting ofthe challenges and problems you feel we face as a society and as a speciality in the yearsto come. If I can at some point manage to wrestle the chain of office from Professor Kane I will wear it withpride while thinking of the proud history of the society and the great names of Irish Rheumatology who haveworn it with such distinction before.

I would like to take this opportunity to thank the outgoing David for his highly successful tenure as President.David brought great energy and ability to the role and the members I know are very grateful for all he achievedduring the past few years. His boots will be hard to fill but I am delighted that David has agreed to take up therole of programme director for Rheumatology with the HSE and I look forward to working closely with David tosecure as bright a future for Rheumatology in Ireland as possible. David has opened membership of the ClinicalAdvisory Group, charged with developing a Model of Care for Rheumatology, to all interested consultantrheumatologists in Ireland and the first of quarterly CAG meetings will be the morning of this meeting. Adoptinga Model of Care is essential for us to work with the HSE to develop Rheumatology in Ireland in a co-ordinatedand appropriately resourced fashion for the future.

It is my belief that Rheumatology faces seismic changes in the coming few years not dissimilar in scale to themetamorphosis which occurred with the advent of the Biologic era in the late 1990’s. Exponential advances inthe field of biologics are providing us with an ever increasing armoury of molecules and targets whilst at thesame time the availability of biosimilar products offers new challenges and opportunities.

I would like to pay special thanks to all our colleagues in the pharmaceutical industry who continue to supportthe ISR generously. Delivering the best treatments to the right patients at the right time remain common goalsfor clinicians and industry alike and I believe the colossal advances in rheumatology evident over the past 15years are testament to this symbiosis.

The academic organisers Sinead Harney and John Ryan have put together an exciting agenda with a clinicalemphasis on Connective Tissue Disease and Vasculitis with case discussion and interaction. International andNational speakers of the highest quality mean we look forward to a thoroughly fascinating day. We are delightedto welcome Dr. Rob. Hendry from the MPS in Edinburgh who has agreed to address the changing claimsenvironment for rheumatology claims in Ireland and the UK.

I would like to express the appreciation of the ISR Board to the society administration including Michael Dineenand Jenny Howard and I would particularly like to wish Jenny a speedy recovery from her recent hip surgery.

I sincerely hope you all have a great time in Cork .

Yours sincerely

Dr Sandy Fraser,ISR President

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PROGRAMME ISR Spring MeetingRochestown Park Hotel Cork, 14th & 15th April 2016

Thursday 14th April

2.30-4.30pm Postgraduate Training DayOrganised by CUH Academic Team Supported Roche Products Ltd.

Friday 15th April

9.30am Registration and welcome

10.00am Dr Rachel Jones - Cambridge University "Update on ANCA associated vasculitis"

10.50am 2 cases with discussion of AAV (SpR)

11.30am Coffee & Pharma Exhibition

12.00noon Prof David Isenberg - University College London"Lupus" – Expert new perspective on an old disease

12.50pm 2 cases with discussion of Lupus (SpR)

1.30pm Lunch & Pharma Exhibition

2.30pm Prof Louise Kenny - UCC"Pregnancy and CTD” - what can go wrong? – how to sort it

3.20pm 2 cases with discussion of management in pregnancy (SpR)

4.00pm Medical Protection Insurance Workshop

Dr Rob HendryMPS Medical Director, Edinburgh.“The changing claims environment in rheumatology in Ireland and the UK”

Q&A

4.45pm Wrap up

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Dr Robert A HendryMedical Protection Society, Edinburgh

Robert was born and brought up in Glasgowand studied medicine at Dundee University.After graduating in 1981 he undertook anumber of hospital appointments beforebecoming a partner in an urban teachingpractice in Dundee in 1986.

He developed an interest in medical law and completed an MPhilin Law and Ethics in Medicine at Glasgow University in 1992.Having done some consultancy work for the Medical ProtectionSociety and having taught part-time at Dundee University, hetook up a permanent appointment as a medicolegal adviser withthe Medical and Dental Defence Union of Scotland in 1996 andremained there until he moved to the Medical Protection Societyto set up their Edinburgh office in 2009.

Robert is a Foundation Fellow of the Faculty of Forensic and LegalMedicine and continues to have an interest in teaching, havinghonorary positions at both the Universities of Glasgow and StAndrews.

Having completed his MBA at Strathclyde University GraduateBusiness School in 2001 he has continued to develop his businessinterests. In 2011 he was appointed Deputy Medical Director andin 2013 became Medical Director of the Medical Protection Societyand is currently responsible for medicolegal services delivered bythe Medical Protection Society to its members worldwide.

Prof David Isenberg University College London

Professor Isenberg is the Arthritis ResearchUK Diamond Jubilee Professor ofRheumatology, University College LondonMedical School, UK. He graduated from theUniversity of London in 1973, after which hepursued his clinical training at UniversityCollege Hospital (UCH), London. He undertook the Jules ThornScholarship) in Rheumatology & Haematology in UCH, afterwhich he became a Research Fellow in Haematology / Oncologyat Tufts University, Boston, USA. He returned to the UK in 1983as a Senior Registrar in Rheumatology at UCH and shortlyafterwards was offered a Consultant Rheumatologist post. He hasbeen Professor of Rheumatology since 1992. He has an extensivepublication record and has been honoured on multiple occasionsfor his research in SLE and other rheumatic diseases. Hereceived the Evelyn Hess prize award in 2010 from The LupusFoundation of America for ‘outstanding contribution to researchand treatment of Lupus’. He was awarded the Roger Demersaward in 2012 from the Laurentian Conference of Rheumatologyfor ‘Unique Contribution to International Rheumatology’.

Speakers

Prof Louise Kenny University College Cork

Prof Louise Kenny is an honours medicalgraduate of Liverpool Medical School, UK(1993) and a Member of the Royal College ofObstetrics and Gynaecologists (2001). Shereceived her PhD in vascular physiology and pharmacology fromthe University of Nottingham, UK in 2003. Louise undertook post-doctoral training whilst concurrently completing her clinicaltraining as a Lecturer at the Maternal and Fetal Health ResearchCentre, University of Manchester, UK. She was awarded CCST bythe Specialist Training Authority of the Medical Royal Colleges, UKin 2005 and was appointed as a Senior Lecturer and ConsultantObstetrician at St Mary’s Hospital, The University of Manchester.Louise moved to University College Cork in 2006 and took up apost as a Senior Lecturer and Consultant Obstetrician andGynaecologist at the newly opened Cork University MaternityHospital where she continued to pursue her long standing clinicaland research interest inuteroplacental insufficiency, adversepregnancy outcome and pregnancy loss. In 2007, Louise wasappointed as a Health Research Board Ireland Clinician Scientist.In July 2009, Louise was awarded a Principal InvestigatorProgramme grant from Science Foundation Ireland to developpredictive biomarkers of poor pregnancy outcome, pioneering anew approach to biomarker development by focusing onmetabolic changes in plasma. Louise was promoted to Professorof Obstetrics at University College Cork in 2009.

Her work has resulted in three patent applications relating topregnancy biomarkers and more than >100 peer reviewedoriginal papers, reviews and book chapters. She is the Editor ofthe 19th Edition of ‘Obstetrics by Ten Teachers’- the world’sleading undergraduate textbook in obstetrics. In addition, Louiseis a reviewer for a wide range of international journals includingthe American Journal of Obstetrics and Gynecology, the BritishJournal of Obstetrics and Gynaecology, the British MedicalJournal, Clinical Chemistry, Reproductive Sciences andHypertension and research funding bodies such as the MedicalResearch Council (UK), the Wellcome Trust, Action Research, theBritish Heart Foundation, Wellbeing, Sparks, the Health ResearchBoard and Science Foundation Ireland.

At CUMH, she is part of the Perinatal Medicine team and has aparticular interest in hypertensive disorders of medicine and othermaternal complications.

Dr Rachel Jones Addenbrooke's Hospital, Cambridge

Dr Rachel Jones is a Consultant Nephrologistwith a specialist interest in vasculitis atAddenbrooke's Hospital, Cambridge. Since 2005she has undertaken clinical research with DavidJayne in Cambridge, focusing on therapeutictrials in primary systemic vasculitis. In 2011 she gained her CCTand undertook a part-time secondment to GlaxoSmithKline,Stevenage from the University of Cambridge, alongside anHonorary Consultant Nephrologist post. At GlaxoSmithKline sheworked on early phase clinical trial design. In June 2013 shereturned to the NHS in her current role as a ConsultantNephrologist, working in the Department of Renal Medicine atAddenbrooke’s Hospital, including a large specialist vasculitis andlupus clinic.

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ISR Board members

Dr Sandy FraserConsultant Rheumatologist, General Physicianand Honorary Senior Lecturer, UniversityHospitals Limerick. Dr. Alexander Frasergraduated in medicine from Trinity CollegeDublin in 1991. He began practicingRheumatology in 1996 and the following yearwas appointed Specialist Registrar in Rheumatology at theYorkshire Deanery. Training with Professor Emery’s group inLeeds he developed a research interest in clinical, immunologicaland therapeutic aspects of Rheumatoid Arthritis, PsoriaticArthritis and the Sero-negative Spondyloarthropathies. He wasappointed Consultant Rheumatologist and Honorary SeniorLecturer at the Leeds Teaching Hospitals NHS Trust, working atThe Leeds General Infirmary and St. James’ University Hospital inOctober 2001, and working closely with Professor Emery andProfessor Doug Veale he published in the area of Angiogenesis,Vascularity and Inflammation in early and established arthritisand Biomarkers of cartilage turnover. Dr Fraser took up hiscurrent appointment as Consultant Rheumatologist, GeneralPhysician and Honorary Senior Lecturer at the UniversityHospitals Limerick in 2006. In conjunction with the University ofLimerick Graduate Entry Medical School (GEMS) Dr. Fraser and histeam have continued their strong academic interests whilemanaging a busy clinical practice.

Professor David KaneProf David Kane attended medical school atTrinity College, Dublin, Ireland and wasconferred MB BCh BAO BA in 1991, PhD in2002 and FRCPI in 2006. He has trained inrheumatology with Prof. Barry Bresnihan andProf. Oliver FitzGerald at St. Vincent’sUniversity Hospital, Dublin, Ireland and withProf Roger Sturrock, Prof Iain McInnes and DrPeter Balint at Glasgow Royal Infirmary, Glasgow, UnitedKingdom. He was appointed as Senior Lecturer in Rheumatologyat the University of Newcastle (2003-2005) and is currentlyworking as Consultant Rheumatologist at the Adelaide and MeathHospital and Clinical Professor in Rheumatology at Trinity CollegeDublin. His special interests are musculoskeletal ultrasound,spondyloarthopathy and synovial inflammation. He is a memberof the European Working Party on Musculoskeletal Ultrasoundand the OMERACT special interest group on musculoskeletalultrasound, previous organiser of the BSR MusculoskeletalUltrasound course and is Faculty member of the EULARMusculoskeletal ultrasound course. He has served as a Boardmember of the Irish Osteoporosis Society, as Treasurer of theIrish Society for Rheumatology and is currently a Board memberof Arthritis Ireland.

Dr Frances StaffordFrances is a graduate of UCD, spent almost adecade in North America, training inRheumatology first at University of Toronto,followed by a fellowship at MassachusettsGeneral Hospital & Harvard Medical School.She was awarded a 4 year Arthritis FoundationPostdoctoral Fellowship, which I completed atthe NIH, and then went on staff at the NIH.Frances is American Board Certified in Internal Medicine and inRheumatology. She has been Consultant at Blackrock Clinic since1995.

Dr Sinéad HarneyDr Sinéad Harney graduated from UCG in1994 and did her specialist training inRheumatology and General Medicine inDublin. She completed her training in Oxfordin 2005 and was awarded a DPhil by thesistitled “Major Histocompatibility Genetics ofRheumatoid Arthritis”. She was appointed toa Consultant Rheumatologist post in CorkUniversity Hospital in 2005 and has worked there since. Shecompleted a Masters in Sports and Exercise Medicine in UCC in2007. Her research interests include – Genetics of inflammatoryarthritis and occult cardiovascular disease in Rheumatoid Arthritisand she has over 90 publications. She is currently the treasurerof the Irish Society of Rheumatology and a board member of theTUE committee of the Irish Sports Council.

Dr Suzanne DonnellyDr Suzanne Donnelly graduated from TrinityCollege Dublin, trained in Ireland and Englandand was appointed consultant rheumatologistat St. George's Hospital and Medical School,London in 2002. She returned to Ireland in2005 to work part time as ConsultantRheumatologist in the Mater MisericordiaeUniversity Hospital. Her clinical andeducational research interests include systemic autoimmunedisease, Systemic Lupus Erythematosus and Care in Medicine.Suzanne has held academic posts in medical education since1996 including in Trinity College Dublin; the University of Oxfordand in London, and joined UCD as Director of Clinical Educationin 2008, to lead the development of early clinical education. Shewas responsible for a series of innovative educational strategiesacross all disciplines including the development of a patienteducator programme in association with Arthritis Ireland. She ledthe first national undergraduate curriculum project in Ireland,published as the ISR Undergraduate Curriculum in Rheumatologyin 2009, and is a contributing author to the textbooks Medicine atA Glance & The Rheumatology Handbook. She was ISR nomineeto the board of Arthritis Ireland (2008-13), a board member ofRaynauds and Scleroderma Ireland (2007-10) and is a medicalpatron of Lupus Group Ireland.

Dr Adrian PendletonConsultant RheumatologistMusgrave Park Hospital, Belfast

ISR AUTUMN MEETING 201615th & 16th September

to be held in Kilashee Hotel, Naas

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Dr Donough HowardDonough Howard is a ConsultantRheumatologist at St James’s Hospital andHermitage Medical Clinic. Dr Howard is thenational specialty director for rheumatology.He graduated from RCSI and completedpostgraduate training both in Ireland and theUS. He previously worked in Lahey ClinicMedical Centre, with academic appointments to both Harvard andTufts Medical Schools. Dr Howard has published in the fields ofvasculitis and also has subspecialty interests in the fields ofscleroderma.

Dr Orla Killeen Dr Orla Killeen qualified from UCG (NUI)Galway in 1996. She trained in GeneralPaediatrics in Our Lady’s Hospital for SickChildren, Crumlin and in Temple StreetUniversity Hospital, Dublin before sub-specialising in Paediatric Rheumatology. Sheundertook her paediatric rheumatology training at Great OrmondStreet Children’s Hospital, London and went on to complete aBarbara Ansell Fellowship in Paediatric Rheumatology in the RoyalHospital for Sick Children, Glasgow. She was appointed asIreland’s first Paediatric Rheumatologist in 2004, and is based atOur Lady’s Children’s Hospital, Crumlin and St Vincent’s UniversityHospital, Dublin since July 2006. She is the Clinical lead for theNational Centre for Paediatric Rheumatology (NCPR), providingcare for patients both on a local and national level up to 18 yearsof age. Her areas of interest include Adolescent RheumatologyTransition Care as well as JIA, Down’s arthropathy and Auto-Inflammatory syndromes.

Dr Eamonn Molloy Eamonn Molloy graduated from UniversityCollege Dublin (1997) and completedrheumatology and internal medicine training inIreland. He obtained an MD at RCSI (2006),which focused on calcium crystal inducedinflammation. From 2005, he underwentsubspecialty fellowship training in vasculitis atthe Cleveland Clinic, completed a MS (Clinical Research) at CaseWestern Reserve University and then joined the staff at theVasculitis Center and RJ Fasenmeyer Center for ClinicalImmunology at the Cleveland Clinic. In 2010, he was appointedas a consultant rheumatologist at St Vincent’s University Hospitaland is a UCD Senior Clinical Lecturer. He is the author ofapproximately 50 publications largely pertaining to vasculitis,complications of biologic therapy and crystal induced arthritis.Currently, his primary research focus is giant cell arteritis.

Dr John Stack (SPR Rep)John Stack is this years SpR representative onthe ISR committee. He is a 4th yearrheumatology SpR currently based at ConnollyHospital Blanchardstown and has previouslyworked at St James Hospital, MidlandsRegional Hospital Mullingar and CorkUniversity Hospital. He is a graduate ofUniversity College Cork.

Dr Clare MatthewsConsultant RheumatologistUlster Hospital, Belfast

The Irish Society forRheumatology wishes to expressits gratitude to all its sponsorsand in particular to the following

‘Major Exhibitors’

AbbVie Ltd

MSD Ireland Ltd

Novartis Ireland Ltd

Pfizer Healthcare Ireland

Roche Products (Ireland) Ltd

A.Menarini Pharmaceuticals LtdActelion Pharmaceuticals UK Ltd

Arthritis IrelandBayer LtdBiogen Ltd

Bristol-Myers Squibb PharmaceuticalsCelgene Ireland Ltd

Eli-Lilly & Co (Ireland) LtdFannin Ltd

Grunenthal Pharma LtdJanssen-Cilag Ltd

Lily UKSwedish Orphan Biovitrum Ltd

UCB (Pharma) Ireland Ltd

The Pharmas listed above have allsupported this meeting through a payment

to exhibit a stand. They have had noinvolvement in any other aspect

of this meeting.

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Welcome to the Spring Conference 2016

Firstly I would like to extend my thanks to the ISR, Michael and Jenny and also to the Pharma companiesfor their continued support towards a wide range of educational opportunities through our variousbursaries.

We had a very successful meeting in Naas last September with presentations from Colin Dunleavy, MaryRyan and Natalie Wallace all from the Weight Management Service in St. Columcille’s Hospital,Loughlinstown, Co. Dublin. The two highest scoring IRHPS abstract submissions also presented theirwork. Congratulations to Rachel Burke, Senior Physiotherapist, Naas, winner of the Professor BarryBresnihan gold medal award and Oriel Corcoran, Clinical Specialist Occupational Therapist, U.H.W. whoclaimed the silver prize. Other awards included the Roche poster awards. The prize winners wereJennifer Ashton and Aisling Brennan who have won the opportunity to attend EULAR in London 2016.The UCB poster award winners were Tom O ‘Dwyer, Paul Kirwan, Stephanie Naromoor, Maria McGrathand Una Martin. The people’s choice award also went to Una Martin. This year’s BSR winners were KarenQuinn and Derek Deely. Congratulations to Louise Larkin, PhD candidate, University of Limerick who wassuccessfully awarded the Janssen Education Bursary in 2015.

I would like to take this opportunity to welcome the IRHPS incoming chair Eileen Shinners from OurLady’s Hospice and Care Service Harolds Cross. Remember Health Professionals this is your society andif you have topics you would like covered in future meetings please contact us. Also keep an eye on ourwebsite www.irhps.ie for news on meetings and educational opportunities.

Best wishes,DEREK DEELYIRHPS Chair

IRHPS Spring 2016 Update

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ISR Presidents

Dr Sandy Fraser 2016 – presentLimerick

Prof D. Kane 2014 – 2016Dublin

Dr G.Wright 2012 – 2014Belfast

Prof Gaye Cunnane 2010 – 2012Dublin

Dr R. Kavanagh 2008 - 2010Galway

Dr J. Lee 2006 - 2008Craigavon

Dr P. O’Connell 2004 - 2006Dublin

Prof O. FitzGerald 2004 - 2002Dublin

Dr A. Taggart 2000 – 2002Belfast

Dr D. Raman 1998 – 2000Sligo

Dr A. Bell 1996 – 1998Belfast

Prof B. Bresnihan RIP1994 – 1996 Dublin

Prof M. Molloy 1992 – 1994Dublin

Dr E. Casey 1990 – 1992Dublin

Dr. S. Roberts 1988 – 1990Belfast

Dr C. Barry RIP1985 – 1987 Dublin

Dr D. Roden RIP1983 – 1985 Dublin

Dr W. Boyd RIP1981 – 1983 Belfast

Dr T. Gregg RIP1979 – 1981 Dublin

Dr J. Molony RIP1977 – 1979 Dublin

Dr M .McMahon RIP1975 – 1977 Cork

Dr T.O’Reilly RIP1973 – 1975 Dublin

Irish Society for Rheumatology Board Members

PRESIDENTDr Alexander Fraser

Consultant RheumatologistMid-Western Regional Hospital

Dooradoyle, Limerick

HONORARY SECRETARYDr Frances Stafford

Consultant RheumatologistBlackrock Clinic, Co. Dublin

HONORARY TREASURERDr Sinéad Harney

Consultant RheumatologistCork University Hospital, Cork

BOARD MEMBERDr Suzanne Donnelly

Consultant RheumatologistMater University Hospital, Dublin 7

BOARD MEMBERProfessor David Kane

Consultant RheumatologistAdelaide and Meath Hospital

Tallaght, Dublin 24

BOARD MEMBERDr Donough Howard

Consultant RheumatologistBeaumont Hospital, Dublin 9

BOARD MEMBERDr Orla Killeen

Paediatric Consultant RheumatologistCrumlin Children’s Hospital, Dublin 12

BOARD MEMBERDr Clare Matthews

Consultant RheumatologistUlster Hospital, Belfast

BOARD MEMBERDr Eamonn Molloy

Consultant RheumatologistSt. Vincent’s University Hospital, Dublin 4

BOARD MEMBERDr John Stack

SpR Representative

BOARD MEMBERDr Adrian Pendleton

Consultant RheumatologistMusgrave Park Hospital, Belfast

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UCB Stand MSD Stand

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BMS Stand AbbVie Stand

Grunenthal Stand Celgene Stand

Prof Trevor Duffy at Roche stand Dr Suzanne Donnelly and Dr Sandy Fraser at Menarini Stand

ISR Autumn 2015

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Cara McDonagh receiving Young Investigator Award from Prof David Kane and Dr Julian Maitland Med Dir UCB

Dr Sinead Harney Hon Tresurer of ISR

Keynote Speakers from St. Columcille’s Hospital with some of the IRHPS Committee EULAR winners Jennifer Ashton and Aisling Brennan

Professor Barry Bresnihan Award Winners

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ISR Autumn 2015

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Dr Gary Wright & Dr Ronan Mullan Dr Cara McDonagh Winner of Young Investigator Award

Prof David Kane Presenting Life Time Achievement Award to Dr Aubrey Bell Prof David Kane, Dr Gary Wright, Mrs Rose Bell & Dr Aubrey Bell

Prof Fergus Shanahan CUH Dr Sureth Rattan, Aarhus Univ. Denmark

Dr Ursula Fearon Researcher SVUH Dr Richard Conway, UCDDr Michelle Trenkman, UCD

ISR Autumn 2015

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Dr Eamon Molloy SVUH & Dr Shawn Chavrimatoo Mrs Rosie Bell, dr Aubrey Bell, Dr Esme Whitehead & Dr Bobby Coughlan

Dr Philip Gardiner & Dr Darragh Foley-Nolan Dr Alex McGregor, Prof Gaye Cunnane, Dr Carmel Silke

Dr John Stack MMUH & Dr Barry O'Shea SJH Dr Andrew Kerins, Professor David Kane & Dr Adrian Pendleton

Prof David Kane making Presentation to Dr Gary Wright on his retirement from board of ISR

Dan Duffy AbbVie, Dr Sureth Rattan Denmark & Dr Len Harty CUH

ISR Autumn 2015

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Attentive Audience Dr Ronan Mullan, Professor David Kane & Dr Jo Kitchen

Dr Fahd A M Ashraf receiving his Poster Prize Prof David Kane presenting Poster Prize to Dr Agnes Sventpetery

Dr Eamon Molloy & Dr Sandy Fraser Incoming President of ISR Prof Gerry Wilson SVUH

Dr Rachel Cole & Dr Miriam O'Sullivan Mark Bullock Guest Speaker Prof Gerd Burmester, Berlin

ISR Autumn 2015

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Dr Sandy Fraser incoming President ISR and Dr John Carey NUIG. Dr Michelle Doran, Prof Oliver Fitzgerald & Dr Frances Stafford

Dr Roger Stewart Receiving his Oral Prtize Eva Mc Cabe Reciving Bernard Connor Medal fro Prof David Kane

Prof Doug Veale presenting cheque to John Church CEO of Arthritis Ireland

Dr Carl Orr receiving his Oral Prize Dr Len Harty receiving his Poster Prize

Dr Xenofon Baraliakos Dr John Carey & Dr Claire Sheehy

ISR Autumn 2015

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