introduction to fmri

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Introduction to fMRI

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Introduction to fMRI. Introduction to fMRI. Instructor:James Danckert Class times:Tuesdays 1:00 pm to 4:00 pm room PAS 4032 Office Hours: Tuesdays and Thursdays 4:00 – 5:00 pm room 4040 PAS or by appointment. Phone:extension 7014 Email: [email protected]. - PowerPoint PPT Presentation

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Page 1: Introduction to fMRI

Introduction to fMRI

Page 2: Introduction to fMRI

Introduction to fMRI

• Instructor: James Danckert

• Class times: Tuesdays 1:00 pm to 4:00 pm room PAS 4032

• Office Hours: Tuesdays and Thursdays 4:00 – 5:00 pm room 4040 PAS or by appointment.

• Phone: extension 7014

• Email: [email protected]

Page 3: Introduction to fMRI

Aims of the course

• To make you familiar with the different designs typically used in fMRI research – e.g., block vs. event related and rapid event related fMRI.

• To expose you to the most common analysis techniques of fMRI including, t-tests, linear correlations, GLM, etc. To point you in the right direction for more novel techniques not yet widely used such as ICA.

• To briefly introduce you to alternate imaging techniques including TMS, PET, EEG etc.

• To provide you with the practical skills to design, conduct and analyze your own fMRI experiment.

Page 4: Introduction to fMRI

Format

• Section 1• didactic lectures from me covering the basics of the technique

• Section 2• each week will examine one aspect of cognition and fMRI• two students will present – one giving a review of the literature thus far (based on a chapter from Cabeza and Kingstone) and the other presenting a recent research article relevant to the topic (each student will be expected to make one of each type of presentation)

Page 5: Introduction to fMRI

Reading

• For the technical side of things you can go through the following two web sites in more detail

• http://www.arts.uwaterloo.ca/~jdancker/fMRI/fMRI_OL.htm - this is my web site for the more technical course delivered last year

• http://defiant.ssc.uwo.ca/Jody_web/fmri4dummies.htm- this is Jody Culham’s web course which I based my course on

• Chapters of Cabeza and Kingstone’s book will be used for the reviews while students will be expected to find their own relevant articles for the recent research paper - search PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

Page 6: Introduction to fMRI

Reading

Page 7: Introduction to fMRI

Other recommended reading!

• John Ralston Saul Voltaire’s Bastards – this book has at least a million messages, one of which is to avoid keeping secrets – in other words, make sure you can communicate your results to anyone!

• Theodore Zeldin An Intimate History of Humanity – Zeldin shows many different viewpoints on life exposing how people forget history or ignore its influence on the present.

• Ramon y Cajal Advice for a Young Investigator – written in the early part of last century this little book (much more so than the other two!) has wisdom relevant to all of us – well worth reading.

Page 8: Introduction to fMRI

Assessment• Critique the following fMRI paper and provide an alternate design that addresses

your criticisms.

Marois, R., Chun, M.M., and Gore, J.C. Neural Correlates of the Attentional Blink. Neuron, 28, 299 – 308.

Your paper should be less than 2000 words and counts for 30% of your mark.

• Design an fMRI study of your own. Present a brief (very brief!) theoretical background, a detailed outline of design and analysis, justifying your choices.

Your paper should be less than 2000 words and counts for 30% of your mark.

• Class presentations – each student will two presentations – one on a review of the literature and another on a recent research article – this is worth 25%

• Students not presenting each week will be responsible for asking questions of the presenters to lead class discussion – this is worth the final 15% of your mark.