introduction to corrective health medicine
TRANSCRIPT
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Introduction to CorrectiveIntroduction to Corrective
Health MedicineHealth Medicine
Japanese College ofJapanese College ofIntravenous MedicineIntravenous Medicine
Osaka, Japan September 25Osaka, Japan September 25thth 20112011
Bradford S. Weeks, M.D.Bradford S. Weeks, M.D.
www.weeksmd.comwww.weeksmd.com www.weeksclinic.comwww.weeksclinic.com [email protected]@weeksmd.com
http://www.weeksmd.com/http://www.weeksmd.com/http://www.weeksclinic.com/http://www.weeksclinic.com/http://www.weeksclinic.com/http://www.weeksmd.com/ -
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GOALS for this PresentationGOALS for this Presentation
1) understand the principles of Corrective Health1) understand the principles of Corrective Health
2) understand the theoretical and practical aspects2) understand the theoretical and practical aspects
of Corrective Healthof Corrective Health
3) Understand how to practice Corrective Health3) Understand how to practice Corrective Health
tomorrowtomorrow in your clinic!in your clinic!
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Reverence and HonorReverence and Honor
to our wise and braveto our wise and brave
TeachersTeachers
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Tenzin Choedrak
Abram Hoffer Hugh Riordan David Horrobin
Otto Wolff
Rudolf Steiner
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Congratulations to youCongratulations to you
for your courage to befor your courage to beinnovative doctors!innovative doctors!
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"A physician once told me that nothing arouses so"A physician once told me that nothing arouses so
much bitter enmity and heated arguments among hismuch bitter enmity and heated arguments among his
colleagues, as the subject of cancer. This may be duecolleagues, as the subject of cancer. This may be due
to the guilty recollections of cancer victims expiringto the guilty recollections of cancer victims expiring
who might have been saved; or of the memories ofwho might have been saved; or of the memories of
patients pronounced hopelessly ill who recoveredpatients pronounced hopelessly ill who recovered
under the treatment of a 'quack,' or whounder the treatment of a 'quack,' or who
miraculously lived without further treatment.miraculously lived without further treatment.
Possibly these guilt reactions and the remorse overPossibly these guilt reactions and the remorse over
exhausting the money of patients and their relativesexhausting the money of patients and their relatives
in futile cancer treatments, account for some of thesein futile cancer treatments, account for some of thesepsychological manifestations which are expressed inpsychological manifestations which are expressed in
hostility and attack."hostility and attack."
Nat Morris (written in 1958)Nat Morris (written in 1958)
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Which box are you thinking outside of?
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Corrective Medicine and Psychiatry
http://var/www/apps/conversion/current/My%20Documents/A%20All%20documents/BSW/ -
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What is Corrective Medicine?What is Corrective Medicine?
CORRECTIVE MEDICINE & PSYCHIATRYCORRECTIVE MEDICINE & PSYCHIATRY
involves the collaborative experience ofinvolves the collaborative experience of
listening with, educating and advising patientslistening with, educating and advising patients
about how to correct imbalances in their fourabout how to correct imbalances in their four
realms of life: their physical bodies, theirrealms of life: their physical bodies, their
vitality, their emotional life and their spiritualvitality, their emotional life and their spiritual
path. This encompasses education andpath. This encompasses education andcounseling concerning the lifestylecounseling concerning the lifestyle NETNET
(Nutrition, Exercise and Thought)(Nutrition, Exercise and Thought)
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The NetThe Net
The Health PyramidThe Health Pyramid
TheThe NETNET
NutritionNutritionExerciseExercise
ThoughtThought
LIFESTYLE FACTORS (85%)
Repair the NET
Nutrition (get it) Exercise (use it) Thoughts (manage it)
Supplementand / or
Detoxify
Drugs Surgery
Hospital
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When your car breaks down,
you have an important choice.
Call a tow truck or.
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Correct the Problem!
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Correct the Problem!
Fill up the gasoline tank!
Put air back in flat tire!
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Pain in ButtockPain in Buttock(Standard of Care)(Standard of Care)
Prescribe pain medicationsPrescribe pain medications
If problem persists, increase dosage.If problem persists, increase dosage.
If problem persists, refer to psychiatrist.If problem persists, refer to psychiatrist.
Eventually, refer to rehabilitation if patientEventually, refer to rehabilitation if patient
becomes addicted to pain medication.becomes addicted to pain medication.Rarely, check to see if the patient is sitting onRarely, check to see if the patient is sitting on
a tacka tack
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Pain in ButtockPain in Buttock(Corrective Health)(Corrective Health)
Delay prescribing pain medicationsDelay prescribing pain medications
Check to see if the patients sitting on a tack!Check to see if the patients sitting on a tack!
If so , teach about tacks (empower the patient)If so , teach about tacks (empower the patient)If so, teach to avoid tacks(preventive care)If so, teach to avoid tacks(preventive care)
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How to Practice Corrective MedicineHow to Practice Corrective Medicine
When in doubt, ask the patient.When in doubt, ask the patient.Alan Tisdale, M.D.Alan Tisdale, M.D.
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The Corrective HistoryThe Corrective History
1) What do YOUthink is wrong with you?
2) What do you THINKis wrong with you?
3) WHATdo you think is wrong with you?
4) What do you think is WRONG with you?
5) What do you think is wrong with YOU?
(Note: the patient is the expert in his or her dis-ease)
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It is easier to measuresomething precisely than it is to
know precisely what you are
measuring
Corrective Laboratory
Testing and Evaluation
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Goal of Corrective Laboratory Testing
1) Take the Inventory(Measure endogenous elements to create a strategy of
replenishment of detoxification)
2) Measure the Performance(biochemical processes)
3) Measure the Results(immune function, detoxification)
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Reference Laboratories
1) www.Europeanlaboratory.nl2) www.Metametrix.com
3) www.Spectracell.com4) www.Doctorsdata.com
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Vitamin Diagnostic Lab www.Europeanlaboratory.nl
Precise testing for orthomolecular metabolismPrecise testing for orthomolecular metabolism
Example:Example:
Nagalase in serum is a sensitive test for monitoring the effect of the therapyNagalase in serum is a sensitive test for monitoring the effect of the therapy
in patients with cancer and certain viral infections, including HIV. Becausein patients with cancer and certain viral infections, including HIV. Becauseof the short half-life of nagalase the method is suitable for monitoringof the short half-life of nagalase the method is suitable for monitoring
various types of therapy. The great sensitivity of the test will help thevarious types of therapy. The great sensitivity of the test will help the
physician / oncologist to obtain a better understanding of the therapyphysician / oncologist to obtain a better understanding of the therapy andand toto
fine-tune the treatment.fine-tune the treatment.
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Metametrix Lab www.Metametrix.com
Organix ProfileOrganix Profile - reveals the nutritional and metabolic basis of patient symptoms,- reveals the nutritional and metabolic basis of patient symptoms,
including anxiety, mood changes, and immune responses.including anxiety, mood changes, and immune responses.Amino Acid ProfileAmino Acid Profile - determines essential amino acid imbalances that affect both physical- determines essential amino acid imbalances that affect both physical
and mental function.and mental function.
Nutrient and Toxic Element ProfilesNutrient and Toxic Element Profiles - identifies a toxic burden, which can render- identifies a toxic burden, which can render
considerable damage to the brain and nervous system as well as sufficiency of nutrientconsiderable damage to the brain and nervous system as well as sufficiency of nutrient
elements.elements.
Fatty Acid ProfileFatty Acid Profile - helps strike the right balance of fatty acids that can impact health and- helps strike the right balance of fatty acids that can impact health anddevelopment.development.
Antioxidant VitaminsAntioxidant Vitamins - measures a total body status of antioxidant nutrients and- measures a total body status of antioxidant nutrients and
nutritional deficiencies.nutritional deficiencies.
Coenzyme Q10Coenzyme Q10 - measures total body status of this antioxidant nutrient and energy- measures total body status of this antioxidant nutrient and energy
pathway cofactor.pathway cofactor.
Lipid PeroxidesLipid Peroxides - measures total serum lipid peroxidation, an indication of whole body- measures total serum lipid peroxidation, an indication of whole bodyfree radical activity.free radical activity.
HomocysteineHomocysteine - identifies total homocysteine in plasma, and elevated levels are an- identifies total homocysteine in plasma, and elevated levels are an
independent risk factor for premature cardiovascular disease and atherothromboticindependent risk factor for premature cardiovascular disease and atherothrombotic
cerebrovascular diseasecerebrovascular disease
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Spectracell Lab www.Spectracell.com
SpectraCells Patented TechnologySpectraCells Patented TechnologySpectraCells patented,SpectraCells patented,
chemically-defined control media contains the minimalchemically-defined control media contains the minimal
amount of each essential micronutrient that is needed toamount of each essential micronutrient that is needed to
support optimal lymphocyte growth or mitogenic response.support optimal lymphocyte growth or mitogenic response.
The functional intracellular status of micronutrients involvedThe functional intracellular status of micronutrients involved
in cell metabolism is evaluated by manipulation of thein cell metabolism is evaluated by manipulation of the
individual micronutrients in the media followed by mitogenicindividual micronutrients in the media followed by mitogenic
stimulation and measurement of DNA synthesis.stimulation and measurement of DNA synthesis.
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Doctors Data Lab www.Doctorsdata.com
Doctors Data, Inc. (DDI) a premier clinical laboratory withDoctors Data, Inc. (DDI) a premier clinical laboratory with
over 30 years experience, provides specialty testing toover 30 years experience, provides specialty testing tohealthcare practitioners around the world. A specialist andhealthcare practitioners around the world. A specialist and
pioneer in essential and toxic elemental testing of multiplepioneer in essential and toxic elemental testing of multiple
human tissues, the laboratory offers a wide array ofhuman tissues, the laboratory offers a wide array of
functional testing. DDIs tests are utilized in the assessment,functional testing. DDIs tests are utilized in the assessment,detection, prevention, and treatment of heavy metal burden,detection, prevention, and treatment of heavy metal burden,
nutritional deficiencies, gastrointestinal function, hepaticnutritional deficiencies, gastrointestinal function, hepatic
detoxification, metabolic abnormalities, and diseases ofdetoxification, metabolic abnormalities, and diseases of
environmental origin.environmental origin.
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Corrective Health MethodologyCorrective Health Methodology
Oral (drink fluid vs. swallow pills)Oral (drink fluid vs. swallow pills)
Sublingual (troche)Sublingual (troche)
Nebulizing (inhalant therapy)Nebulizing (inhalant therapy)
Transdermal (oils, gel, hormonese)Transdermal (oils, gel, hormonese)
IM - intramuscularIM - intramuscular
IV - intravenous (bag or slow pushIV - intravenous (bag or slow push ((SIVP)SIVP)
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Benefits and Risks of OralBenefits and Risks of Oral
-- ease of administrationease of administration
- dose titration- dose titration- relatively inexpensive- relatively inexpensive
- teas > power > capsule >tablet- teas > power > capsule >tablet
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Benefits and Risks of SublingualBenefits and Risks of Sublingual
- immediate absorption- immediate absorption
- avoids liver (first pass metabolism)- avoids liver (first pass metabolism)
- lozenge, troche , dropper- lozenge, troche , dropper
BUTBUT
-- requires patiencerequires patience
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Benefits and Risks of NebulizingBenefits and Risks of Nebulizing
- inhalant (direct application),highly absorbable,- inhalant (direct application),highly absorbable,- retrograde transport allowing direct access to CNS,- retrograde transport allowing direct access to CNS,
- avoid first pass liver metabolism so more accurate dosing.- avoid first pass liver metabolism so more accurate dosing.
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Nebulized Hydrogen PeroxideNebulized Hydrogen Peroxide
1) Carrier solution: D5W volume =250cc1) Carrier solution: D5W volume =250cc
2) Hydrogen Peroxide 2.5 cc - 5 cc of 0.3% mm2) Hydrogen Peroxide 2.5 cc - 5 cc of 0.3% mm
sulfate 500mg/cc use 1 -2 ccsulfate 500mg/cc use 1 -2 cc3) Manganese sulfate 0.1mg/cc use 5-10cc3) Manganese sulfate 0.1mg/cc use 5-10cc4) Add NOTHING else no vitamins or minerals4) Add NOTHING else no vitamins or minerals
Use 5 cc at at time - 4-6 times a day for 10 minutesUse 5 cc at at time - 4-6 times a day for 10 minutes
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Benefits and Risks of TransdermalBenefits and Risks of Transdermal
1)1) ease of applicationease of application
2) avoid liver (first pass metabolism)2) avoid liver (first pass metabolism)
3) rash or skin sensitivity3) rash or skin sensitivity
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Benefits and Risks of IMBenefits and Risks of IM
1) 100% absorption1) 100% absorption
2) Sustained release2) Sustained release
3) Easy to administer3) Easy to administer4) Patients can self-administer4) Patients can self-administer
Risk: Infection, if not done right!Risk: Infection, if not done right!
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Risk of IM shotRisk of IM shot
Photo of lesion from B vitamin IM shot givenPhoto of lesion from B vitamin IM shot given
superficially by patientsuperficially by patient
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Benefits and Risks of IV
1) 100% absorption
2) rapid delivery rapid benefits
3) no first pass metabolism
4)Once started, cant reverse!
5)Can correct, though6)Anaphylaxis, Infection, Phlebitis
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Side effects with HD Vitamin CSide effects with HD Vitamin C
Hypoglycemia vs. HypocalcemiaHypoglycemia vs. Hypocalcemia
Sx: Chills and shaking (often if patient has not eatenSx: Chills and shaking (often if patient has not eaten
enough before the IV)enough before the IV)
Suspect: low calcium Rx Calcium gluconate 1000 mgSuspect: low calcium Rx Calcium gluconate 1000 mg
and 400 mg magnesium chloride to the bagand 400 mg magnesium chloride to the bag
Suspect Low blood sugar Rx Dextrose 10 grams IVPSuspect Low blood sugar Rx Dextrose 10 grams IVP
(Recall: finger stick ->unreliable after vitamin C IV).(Recall: finger stick ->unreliable after vitamin C IV).
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EXAMPLE: IV Hydrogen PeroxideEXAMPLE: IV Hydrogen Peroxide
1) use 25 gauge needle or angiocath1) use 25 gauge needle or angiocathChoose largest and most stable veinChoose largest and most stable vein
2) Carrier solution: D5W volume =250cc2) Carrier solution: D5W volume =250cc
3) Hydrogen Peroxide 2.5 cc - 5 cc of 0.3%3) Hydrogen Peroxide 2.5 cc - 5 cc of 0.3%4) Magnesium sulfate 500mg/cc use 1 -2 cc4) Magnesium sulfate 500mg/cc use 1 -2 cc
5) Manganese sulfate 0.1mg/cc use 5-10cc5) Manganese sulfate 0.1mg/cc use 5-10cc6) Add NOTHING else no vitamins or minerals6) Add NOTHING else no vitamins or minerals
7) Infusion rate: 100cc / hour7) Infusion rate: 100cc / hour8) Side effect: phlebitis (vein irritation) so do8) Side effect: phlebitis (vein irritation) so do notnot useuse
same site day after day.same site day after day.
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In-dwelling
catheter port
Easy and
safe access
Preferred
for IPT CancerCare in office
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Oxygen breathing may be a cheaper and safer alternative toOxygen breathing may be a cheaper and safer alternative to
exogenous erythropoietin (EPO)exogenous erythropoietin (EPO)
Recently discoveredRecently discovered normobaric oxygen paradox demonstrates thatnormobaric oxygen paradox demonstrates that
renal tissue can be stimulated to increase EPO production via a simplerenal tissue can be stimulated to increase EPO production via a simple
pattern of oxygen breathing at normal atmospheric pressures. Thispattern of oxygen breathing at normal atmospheric pressures. This
leads directly to the hypothesis that oxygen breathing may provideleads directly to the hypothesis that oxygen breathing may provide
chemotherapy patients with a convenient and inexpensive alternativechemotherapy patients with a convenient and inexpensive alternativeto ESAs. Stimulating endogenous EPO production eliminates theto ESAs. Stimulating endogenous EPO production eliminates the
small risk of immune system reaction associated with ESAs. Further,small risk of immune system reaction associated with ESAs. Further,
the endogenous physiological EPO doses provided by this method maythe endogenous physiological EPO doses provided by this method may
be safer, in terms of cancer mortality, than the exogenousbe safer, in terms of cancer mortality, than the exogenous
pharmacological doses inherent in ESA administration.pharmacological doses inherent in ESA administration.
Author: R. BurkAuthor: R. Burk Medical HypothesisMedical Hypothesis published on line 5/ 11/ 07published on line 5/ 11/ 07
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Corrective Protocols
for Common Ailments
Headache
Angina (chest pain)
Premenstrual crampsBack pain
Asthma
SIVP Magnesium sulfate5 cc mixed with
Pyridoxine HCL 3cc
Side- Effects:Side- Effects:
Heat flush,Heat flush,
Nausea, FaintingNausea, Fainting
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Magnesium for Angina
RX SIVP in clinic - easy and effective, sent patient
home on oral supplemental magnesium.
CONCLUSION:
This study demonstrates that the degree of intracellular
magnesium deficiency in women with variant angina is
closely related to the frequency of chest pain.
Source: Herz. 2004 May;29(3):299-303.Relationship between the degree of intracellular
magnesium deficiency and the frequency of chest pain in
women with variant angina. Guo H, Cheng J
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Magnesium for Heart HealthMagnesium for Heart Health
Since Mg(2+)-ATP is the controlling factor for the rate-limiting enzyme in the cholesterol
biosynthesis sequence that is targeted by the statin pharmaceutical drugs, comparison of the effectsof Mg(2+) on lipoproteins with those of the statin drugs is warranted. Formation of cholesterol in
blood, as well as of cholesterol required in hormone synthesis, and membrane maintenance, is
achieved in a series of enzymatic reactions that convert HMG-CoA to cholesterol. The rate-limiting
reaction of this pathway is the enzymatic conversion of HMG CoA to mevalonate via HMG CoA.
The statins and Mg inhibit that enzyme. ..These effects of statins derive less
from their lowering of LDL-C than from their reduction of mevalonate formation which improvesendothelial function, inhibits proliferation and migration of vascular smooth muscle cells and
macrophages, promotes plaque stabilization and regression, and reduces inflammation, Mg has
effects that parallel those of statins. For example, the enzyme that deactivates HMG-CoA Reductase
requires Mg, making Mg a Reductase controller rather than inhibitor. Mg is also necessary for the
activity of lecithin cholesterol acyl transferase (LCAT), which lowers LDL-C and triglyceride levels
and raises HDL-C levels. Mg at optimal cellular concentration is well accepted as
a natural calcium channel blocker. More recent work shows that Mg also acts
as a statin.
SOURCESOURCE J Am Coll Nutr. 2004 Oct;23(5):501S-505S. Comparison of mechanism and functional effects of magnesium and statin
pharmaceuticals. Rosanoff A, Seelig MS
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Case Studies: Non-Healing Neck FractureCase Studies: Non-Healing Neck Fracture
Neuropathy and FibromyalgiaNeuropathy and Fibromyalgia
55 yr old woman: former gymnast
DX Non-healing neck fracture, neuropathy, FM
RX IV magnesium / phosphatidyl choline
Electrical stimulation: www.neurocare.com
Oral replenishmentTransdermal testosterone and DHEA
Resolution of symptoms: no pain
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Corrective Protocols
for Common Ailments
Tinnitus
Asthma
IM Hydroxycobalamin1000 4000 mcg
Side- Effects:Side- Effects:
Increased energyIncreased energy
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Corrective Protocols
for Common Ailments (cont.)
Macular Degeneration IV
Oral
Selenium 400mcgSelenium 400mcg
Zinc 50mgZinc 50mg
Taurine 500mgTaurine 500mg
Side- Effects:Side- Effects:
None at dosageNone at dosage
i l
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Corrective Protocols
for Common Ailments (cont.)Psychiatric:
Anxiety
Depression
Obsessive Compulsive
Autism
Low Libido
Oral
Sub-lingual
IM
Oxytocin 10 unitsOxytocin 10 units
Side- Effects: relaxedSide- Effects: relaxedand warmand warm
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Corrective Protocols
for Common Ailments (cont.)Neurologic:
Autism
Aspergers
Chronic Fatigue
Multiple Sclerosis
Oral
IM
Oxytocin 10U BLAOxytocin 10U BLA
Oxytocin 10 U BLAOxytocin 10 U BLA
Side- Effects:Side- Effects:
increased circulationincreased circulationsense of warmthsense of warmth
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Corrective Hormone Therapy: Oxytocin
Oxytocin (OT) is a hormone produced in many parts of the body. Inthe brain, it is produced and released on a daily rhythm with it's
peak in the human brain occurring at around noon. OT is also
produced in the posterior retina, in the pineal gland, thymus,
pancreas, testicle, ovary, and adrenal glands.
Oxytocin has also become the subject of studies in female sexual
dysfunction specifically difficulty achieving orgasm. Oxytocin
increases sexual receptivity and counteracts impotence. (Pedersen,
C.A., 2002), (Arletti, 1997)CC http://www.youtube.com/watch?v=Y2mHO6QrKV0&feature=related
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Oxytocin and Social FunctionOxytocin and Social Function
Natural Hormone Reduces Stress Hormones In ArguingNatural Hormone Reduces Stress Hormones In ArguingCouples (Dec. 9, 2008) A dose of the hormone OxytocinCouples (Dec. 9, 2008) A dose of the hormone Oxytocin
reduces the stress hormone Cortisol in arguing couples.reduces the stress hormone Cortisol in arguing couples.
Oxytocin: Its a Mom and Pop Thing (Aug. 22, 2010) Oxytocin: Its a Mom and Pop Thing (Aug. 22, 2010) The hormone oxytocin has come under intensive study inThe hormone oxytocin has come under intensive study in
light of emerging evidence that its release contributes to thelight of emerging evidence that its release contributes to the
social bonding that occurs between lovers, friends, andsocial bonding that occurs between lovers, friends, and
colleagues.colleagues.
Source:Source:http://weeksmd.com/2011/08/the-dark-side-of-oxytocin/http://weeksmd.com/2011/08/the-dark-side-of-oxytocin/
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Case Study: PTSD and Aspergers Syndrome
ID: 67 yr old war veteran with a 45 year history of
Dx: Post traumatic stress disorder , high functioning
work-a holic, no family life, no relationships
Sx: isolating, lonely, suicidal, depressed, insomnia
Lab: high stress neurotransmitters
Rx: Oxytocin 10units BLA a day
Results: I am having the best talks ever with friendsand family. No more thoughts of war trauma.
I am finally fulfilling my destiny. I am happy.
O t i h ti t i t ti ilk l td
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Oxytocin has action on uterine contraction, milk letdown, orgasm,
sexual arousal, bonding and maternal behavior. Side effects of
Oxytocin from the literature on injection and nasal include:
hemorrhage in the brain and uterus, increased blood pressure, heart rateand cardiac output, uterine contractions.
References:-Hollander E, Novotny S, Hanratty M, Yaffe R, DeCaria CM, Aronowitz BR, Mosovich S (2003):
Oxytocin infusion reduces repetitive behaviors in adults with autistic and Aspbergers disorders.
Neuropsychopharmacology 28:193-198.-Insel TR, OBrien DJ, Leckman JF (1999): Oxytocin, vasopressin, and autism: is there a connection?Biol
Psychiatry 45:145-147.
-McCarthy MM, Altemus M (1997): Central nervous system actions of oxytocin and modulation of
behavior in humans.Mol Med Today 3:269-275.
-Modahl C, Green L, Fein D, Waterhouse L, Feinstein C, Morris M, Levin H (1998): Plasma oxytocin
levels in autistic children. Biol Psychiatry 43:270-277.
-Panksepp J (1992): Oxytocin effects on emotional processes: separation distress, social bonding, and
relationships to psychiatric disorders. Ann NY Acad Sci 652:243-252.
-Popik P, Vetulani J, van Ree JM (1992): Low doses of oxytocin facilitate social recognition in rats.
Psychopharmacology (Berl) 106:71-74
-Waterhouse L, Fein D, Modahl C (1996): Neurofunctional mechanisms in autism.Psychol Rev 103:457-
489.
C ti P t l
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Corrective Protocols
for Common Ailments (cont.)Psychiatric:Schizophrenia
Anxiety
Depression
Obsessive Compulsive
Autism
Oral Niacin 500mg TIDNiacin 500mg TID
Vitamin C 1gm TIDVitamin C 1gm TID
Gaba 500mg TIDGaba 500mg TID
Tryptophan 1 g HSTryptophan 1 g HS
Side- Effects:Side- Effects:
Niacin FlushNiacin Flush
Loose stoolsLoose stools
Long lifeLong life
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N= 30 acute schizophrenic patients randomized to placebo,
niacinamide, or niacin.
Rx: 1 gram TID for 30 days,
Follow-up: 1 year.
Results: After the 1 year, the patients who were given vitamin B-3
with the standard treatments at that time had more than double
the recovery rate (80%) compared to patients in the placebo group
(33%).
The First Double Blind Study in Psychiatry 1952-1957
Dr. Abram Hoffer
S l t d A ti l Ni i d M t l Ill
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1) Nicotinamide and neutrophilia. Hoffer A. Nat Med. 2010 Jan;16(1):23;
2) Successful treatment of schizophrenia requires optimal daily doses of
vitamin B3. Hoffer A, Prousky J.Altern Med Rev. 2008 Dec;13(4):287-91.
3) Discerning the Mauve factor, Part 2. McGinnis WR, Hoffer A. et alAltern
Ther Health Med. 2008 May-Jun;14(3):56-62.
4) Discerning the Mauve Factor, Part 1. McGinnis WR, Hoffer A. et alAltern
Ther Health Med. 2008 Mar-Apr;14(2):40-505) Comments on "Mega-dose vitamins and minerals in the treatment of
nonmetastatic breast cancer: an historical cohort study". Hoffer A.Integr
Cancer Ther. 2003 Jun;2(2):155-7.
6) Schizophrenia and cancer: the adrenochrome balanced morphism. Foster H,
Hoffer A.Med Hypotheses 2004;62(3):415-9.
7) The two faces of L-DOPA: benefits and adverse side effects in the treatmentof Encephalitis lethargica, Parkinson's disease, multiple sclerosis and
amyotrophic lateral sclerosis. Foster H, Hoffer A. Med Hypotheses.
2004;62(2):177-81.
Selected Articles on Niacin and Mental Illness
C ti P t l
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Corrective Protocols
for Common Ailments (cont.)Fatigue
Depression
Memory lossEarly onset dementia
IM Vitamin B shots:Vitamin B shots:-Folic Acid 0.5cc-Folic Acid 0.5cc
-Methylcobalamine 1.0cc-Methylcobalamine 1.0cc
-B complex 1.0cc-B complex 1.0cc
-Pyridoxine HCL 0.5cc-Pyridoxine HCL 0.5cc-Glutathione 200mg-Glutathione 200mg
Side- Effects:Side- Effects:
more energymore energy
clear thinkingclear thinking
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Corrective Protocols
for Common Ailments (cont.)Influenza SIVP
Oral
MeyerMeyers Cocktails Cocktail
Side- Effects: noneSide- Effects: none
Vitamin A PalmitateVitamin A Palmitate100,000 IU at first sign and100,000 IU at first sign and
repeat that night (not morerepeat that night (not more
than 3 days)than 3 days)
Side-effect: Vit A toxicity ifSide-effect: Vit A toxicity if
prolongedprolonged (more than 5 days)(more than 5 days)
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Influenza VaccinesInfluenza Vaccines
The principle of fully Informed ConsentThe principle of fully Informed ConsentIt is very important to note that thimerosalIt is very important to note that thimerosal
(ethyl mercury a neurotoxin!) has never been(ethyl mercury a neurotoxin!) has never been
removed from flu shots. With each flu shot,removed from flu shots. With each flu shot,the person receives the full 25 micrograms ofthe person receives the full 25 micrograms of
deadly-mercury.deadly-mercury.
Thimerosal contains 49.6 percent mercury byThimerosal contains 49.6 percent mercury byweight and is metabolized into ethylmercuryweight and is metabolized into ethylmercury
and thiosalicylateand thiosalicylate
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Corrective Protocols
for Common Ailments (cont.)
Influenza Nebulizer H2O2 orH2O2 or
Selenium orSelenium or
Zinc orZinc or
Iodine orIodine or
Vitamin A palmitateVitamin A palmitate
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Corrective Iodine Therapy
Iodoral (5 mg iodine and 7.5 mg iodide as
the potassium salt).
To reach a full load of iodine, load your
patients with 4 Iodoral tablets and 8 drops
of Lugols solution for a three monthperiod.
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Breast Disease
Dupuytrens Contracture Excess Mucous Production
Fatigue
Fibrocystic Breasts
Hemorrhoids
Headaches and Migraine
Headaches
Keloids
Ovarian Cysts
Parotid Duct Stones
Peyronies Disease
Sebaceous Cysts Thyroid Disorders
Cancers (breast, ovarian,
thyroid, prostate)
Disorders treated with iodine
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)Neurologic:
Dementia
Alzheimers
Memory Disorder
IV
IM
PTC (phosphatidylPTC (phosphatidyl
choline)choline)
PSE (paraspinalPSE (paraspinal
etanercept)etanercept)Vitamins B shot:Vitamins B shot:Hydroxycobalamin 1000mcgHydroxycobalamin 1000mcg
B complex 1 ccB complex 1 cc
Pyridoxine HCL 0.5ccPyridoxine HCL 0.5cc
Folate 0.5 ccFolate 0.5 cc
Side- Effects: noneSide- Effects: none
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Para-spinal InjectionsPara-spinal Injections
TNF alpha blockers (Etanercept)TNF alpha blockers (Etanercept)
Anti-Inflammatory drugsAnti-Inflammatory drugs
Nootropic agentsNootropic agents
Nutrients (hydroxycobalamin)Nutrients (hydroxycobalamin)
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Para-Spinal EtanerceptPara-Spinal Etanercept
Discovery substantial physiologic continuityDiscovery substantial physiologic continuity
between veins, venous sinuses, venousbetween veins, venous sinuses, venous
plexuses of the brain and the spine:plexuses of the brain and the spine:
cerebrospinal venous systemcerebrospinal venous system
Rationale - injecting in to paravetebral venousRationale - injecting in to paravetebral venous
plexus then placing patient in Trendelenbergplexus then placing patient in Trendelenberg
position (head down) can deliver medicine toposition (head down) can deliver medicine tothe brain .the brain .
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Batsons PlexusBatsons Plexus
The seminal work regarding the anatomy andThe seminal work regarding the anatomy andphysiology of the CSVS was done by Oscarphysiology of the CSVS was done by Oscar
Batson, a pioneering professor at theBatson, a pioneering professor at the
University of Pennsylvania, in the 1940's.University of Pennsylvania, in the 1940's.Although "Batson's Plexus" has achievedAlthough "Batson's Plexus" has achieved
widespread recognition, much of his highlywidespread recognition, much of his highly
important work never achieved the scientificimportant work never achieved the scientific
dissemination it deserved.dissemination it deserved.
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Batson in the 1940sBatson in the 1940s
Demonstrated that the venous vertebral systemDemonstrated that the venous vertebral system
(VVS) was angiographically linked to the(VVS) was angiographically linked to the
cranial venous system (CVS) and thatcranial venous system (CVS) and that
retrograde flow to the brain was possible dueretrograde flow to the brain was possible dueto a lack of venous valvesto a lack of venous valves
A wide communication of the vertebralA wide communication of the vertebral
venous system with the intracranial,venous system with the intracranial,intrathoracic and intra-abdominal veinsintrathoracic and intra-abdominal veins
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No valves in the CSVS!No valves in the CSVS!
bidirectional and retrograde venous flow inbidirectional and retrograde venous flow in
the CSVS to equalize pressure, tothe CSVS to equalize pressure, to
resdistribute blood, in and out of this plexusresdistribute blood, in and out of this plexus
blood runs, not unlike earliest conceptions of nblood runs, not unlike earliest conceptions of nebb and flow Herlihyebb and flow Herlihy
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By-Passing the Blood
Brain Barrier
Direct injection, using sterile
technique, can deliver
therapeutic agents into the
plexus of paravertebral veinsallowing for delivery into
brain once the patient is
placed in
Trendelenberg position for
15 minutes.Immediate benefit is noted
by patient and family.
f
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PSE ReferencesPSE References
Perispinal administration of anti-TNF agentresults in rapid cognitive improvement in AD
Nature Clinical Practice Neurology (2008) 4,
181 doi:10.1038/ncpneuro0763
TNF-alpha Modulation for Treatment ofTNF-alpha Modulation for Treatment ofAlzheimer's Disease: A 6-Month Pilot StudyAlzheimer's Disease: A 6-Month Pilot Study
MedGenMedMedGenMed. 2006; 8(2): 25.. 2006; 8(2): 25.
ByBy Edward Tobinick, MD,Edward Tobinick, MD,Assistant Clinical Professor of MedicineAssistant Clinical Professor of Medicine,,
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Case Studies:Case Studies: Alzheimers Dementia
ID: 81 yr old man, former corporate executiveSx: MSE -not oriented to person, place or time, not able to be
alone, gets lost, thinks his wife is another woman invading his
home and tells her Shame on you. Go home!
Lab: low oxygen saturation, low B12, global malnutrition perSpectracell Lab (micronutrient panel) high homocysteine,
Rx: PSE with IM vitamin B12 and SIVP PTC, replenishment,
C-pap machine for oxygenation at night;
Result: oriented to person and place, able to be left alone,joking, responding to jokes, family more relaxed, recognizes
his wife again. No more heartbreak.
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
Radiation Exposure IV High Dose AscorbicHigh Dose Ascorbic
Acid (vitamin C)Acid (vitamin C)
Up to 100g over 100 minutesUp to 100g over 100 minutes
in 500 cc sterile water within 500 cc sterile water withMagnesium sulfate 5cc andMagnesium sulfate 5cc and
Calcium Gluconate 3-5 ccCalcium Gluconate 3-5 cc
Side- Effects: thirst andSide- Effects: thirst andhypoglycemiahypoglycemia
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
Radiation Exposure Oral Saturated Solution ofSaturated Solution of
Potassium IodidePotassium Iodide
(SSKI)(SSKI)
Side- Effects:Side- Effects:
enhanced metabolismenhanced metabolism
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SSKI for Radiation Exposure
World Health Organization (WHO) recommended dosage
for radiological emergencies involving radioactive iodine
Age KI in mg per day
Over 12 years old 1303 12 years old 65
1 36 months old 32
< 1 month old 16
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
Radiation Exposure Oral GlandRegenGlandRegen
(brown seaweed)(brown seaweed)
with Fucanoidwith Fucanoid
Vitamin A palmitateVitamin A palmitate
Side- Effects: noneSide- Effects: none
at optimal dosageat optimal dosage
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
Radiation Exposure IM Honey Bee VenomHoney Bee Venom
Side- Effects:Side- Effects:swelling and rednessswelling and redness
localized feverlocalized fever
Adrenal fatigueAdrenal fatigue
Honey Bee Venom protects against radiation toxicityHoney
Bee Venom protects against radiation toxicity
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Honey Bee Venom protects against radiation toxicityHoney Bee Venom protects against radiation toxicityUNCLASSIFIED
U. S. Naval Radiological Defense Laboratory San Francisco, California 9U135
INCREASED RADIATION RESISTANCE OF MICE INJECTED WITHBEE VENOM ONE DAY PRIOR TO EXPOSUREShipman, William H. Cole, Leonard J. 2 March 1967
DISTRIBUTION STATEMENT SPONSORING MILITARY ACTIVITY Bureau of Medicine and Surgery Washington, D.C. 20390
Mice were injected with bee venom dissolved in a 0.90 NaCl solution. Thisinjection was given either intraperitoneally or subcutaneously 24hours before the
mice were irradiated with X rays. It was found that, after exposure to a lethal dose
of radiation (800 - 850 R) the venom-injected mice had a consistently higher
number of survivals than the controls, and that the subcutaneously-injected mice
had a higher number of survivals than the intraperitoneally-injected mice. The
question as to whether this radioprotective effect of bee venom is due to its gen-
eral stress-like effect, or to the action of a specific chemical component has been
discussed.
Source: http://www.dtic.mil/cgi-bin/GetTRDoc?Location=U2&doc=GetTRDoc.pdf&AD=AD0648139Source: http://www.dtic.mil/cgi-bin/GetTRDoc?Location=U2&doc=GetTRDoc.pdf&AD=AD0648139
Honey Bee Venom protects againstHoney
Bee Venom protects against
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Honey Bee Venom protects againstHoney Bee Venom protects against
radiation toxicityradiation toxicity
Well controlled studies showing statistically significantWell controlled studies showing statistically significant
improved survival in mice treated pre-radiation withimproved survival in mice treated pre-radiation with
BVT. "All members of the control group died at 15 days,BVT. "All members of the control group died at 15 days,
whereas 20% of the intra-peritoneally injected group andwhereas 20% of the intra-peritoneally injected group and80% of the subcutaneously injected group were alive at80% of the subcutaneously injected group were alive at
30 days.30 days.
Source: Shipman, W.Source: Shipman, W. Increased Resistance of Mice to X-Radiation afterIncreased Resistance of Mice to X-Radiation after
Injection of Bee Venom.Injection of Bee Venom. Nature.Nature. 7/15/67. vol 215, No.5098, pp311-2.7/15/67. vol 215, No.5098, pp311-2.
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Give me the power toGive me the power to
createcreate feverfever
and I will cureand I will cure
allall illness.illness.
ParamenidesParamenides(500 B.C.)(500 B.C.)
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My teacher
Charles
Mraz
Beekeeper,
Master
Apitherapist
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Honey bee stinger in a finger knuckle
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Case Study:
Dx: Car Accident withHarrington Rods placed
not successful surgery
Rx: Bee venom therapy
to soften scar tissueand improve circulation
in chronic damaged
tissue.
Result: Full range on
motion restored.
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
Cancer IV Ascorbic acidAscorbic acid
(Vitamin C)(Vitamin C)
Side- Effects:Side- Effects:hypoglycemiahypoglycemia
HypocalcemiaHypocalcemia
Benefits: Long life andBenefits: Long life andlow cardiac risklow cardiac risk
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
Malaria InsulinPotentiated
Therapy (IPT)
using
1/4 full dose of theconventional dose ofanti-malaria drug
Side-Effects:Side-Effects:
hypoglycemiahypoglycemia
(sweating)(sweating)
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
LymesDisease
InsulinPotentiated
Therapy
(IPT) using
1/2 full dose of theconventional dose ofDoxicycline and
Acyclovir
Side-Effects:Side-Effects:
hypoglycemiahypoglycemia(sweating)(sweating)
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
Cancer IV Selenium seleniteSelenium selenite
5mg/ml (not mcg!)5mg/ml (not mcg!)
Side- Effects:Side- Effects:
Anemia,Anemia,
neurotoxicity andneurotoxicity and
vision loss vision loss if excessiveif excessive
Corrective Protocols
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Corrective Protocols
for Common Ailments (cont.)
Cancer IV Sodium SeleniteSodium Selenite
5mg, 10mg, 15mg5mg, 10mg, 15mg
(not micrograms)(not micrograms)
In 500cc nl salineIn 500cc nl saline
(not within three days of(not within three days of
antioxidant IVs noantioxidant IVs no
vitamin C)vitamin C)
Side- Effects: anemiaSide- Effects: anemia
Selenium toxicitySelenium toxicity
F 2(H2O)4(S O3)2
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Fe2(H2O)4(SeO3)2One proposed mechanism for the effects of cancer treat- ment
by selenium compounds is the direct action of pro- oxidant
selenometabolites to generate ROS, resulting in cellular toxicity
This ROS-generation mechanism involves the metabo- lism of
selenite and selenate to generate hydrogen selenide (H2Se), a
by-product of selenium metabolic pathway. High levels ofselenide can then react with oxygen to produce ROS, resulting
in oxidative damage to cells.
Source: Cell Biochem Biophys (2010) 58:123 DOI 10.1007/ Antioxidant andAnticancer Properties and Mechanisms of Inorganic Selenium, Oxo-Sulfur, and Oxo-
Selenium Compounds Ria R. Ramoutar
S l i d Ad i iS l i d Ad i i
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Selenium and AdriamycinSelenium and Adriamycin
The anti-tumor effect of adriamycin (ADM) used incombination with Se NPs was investigated. It is found that both
drugs were able to inhibit cell proliferation in a dose-dependent
way and the combined treatment with ADM and Se NPs was
more effective in inhibiting cell growth than each of the twodrugs alone.
Source:Biosens Bioelectron.2008 Nov 14. In vitro study on the individual andsynergistic cytotoxicity of adriamycin and selenium nanoparticles against
Bel7402 cells with a quartz crystal microbalance.
Tan L, Jia X, Jiang X, Zhang Y, Tang H,Yao S,Xie Q.
S di S l iS di S l i
http://var/www/apps/conversion/current/tmp/scratch14077/jour',%20'Biosens%20Bioelectron.http://var/www/apps/conversion/current/tmp/scratch14077/jour',%20'Biosens%20Bioelectron.http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Tan%20L%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Jia%20X%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Jiang%20X%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Zhang%20Y%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Tang%20H%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Tang%20H%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Yao%20S%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Yao%20S%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Xie%20Q%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Xie%20Q%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Yao%20S%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Tang%20H%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Zhang%20Y%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Jiang%20X%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Jia%20X%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Tan%20L%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstracthttp://var/www/apps/conversion/current/tmp/scratch14077/jour',%20'Biosens%20Bioelectron. -
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Sodium SeleniteSodium Selenite
Na2SeO3 is the compound of choice for bothantioxidant and anticancer studies.
MOA: selenocysteine containing enzymes such as
GPx and thioredoxin reductases to prevent radicalformation is a possible mechanism. The generation of
hydrogen selenide from selenometabolites such as
selenite to produce toxic ROS is also suggested as a
possible mechanism for the pro-oxidant and anticancerproperties of inorganic selenium compounds
Corrective Protocols
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Co ect ve otoco s
for Common Ailments (cont.)
Cancer Oral Vitamin A PalmitateVitamin A Palmitate
Side- Effects: DoseSide- Effects: Dose
related (can push torelated (can push to
75,000 U/day75,000 U/day
A OK f C
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A OK for CancerA OK for Cancer
Anti-cancer agent (esp lung and epithelial cell source):Anti-cancer agent (esp lung and epithelial cell source):
Suppresses the growth of cervical carcinoma cells via a sustainedSuppresses the growth of cervical carcinoma cells via a sustained
activation of interferon regulatory factor 1 and activation caspase-1activation of interferon regulatory factor 1 and activation caspase-1
Beta-carotene inhibited lung metastasis induced by B16F-10Beta-carotene inhibited lung metastasis induced by B16F-10
melanoma cells in the C57BL/6 mice model by 71% compared tomelanoma cells in the C57BL/6 mice model by 71% compared to
controls due in part to a reduction of pro-metastatic adents includingcontrols due in part to a reduction of pro-metastatic adents including
hydroxyproline, hexoasmine, sialic acid and uronic acid.hydroxyproline, hexoasmine, sialic acid and uronic acid.Prevents blindness in malnourished childrenPrevents blindness in malnourished children
Oral anti-viral agent (pneumonia, bronchitis)Oral anti-viral agent (pneumonia, bronchitis)
Prevents intravaginal transmission of HIV virus from infected motherPrevents intravaginal transmission of HIV virus from infected mother
to neonate better than any other know substance;to neonate better than any other know substance;
Vitamin A deficiency reduces the number of osteoclasts resulting inVitamin A deficiency reduces the number of osteoclasts resulting inexcessive deposition of periosteal bone by the unchecked activity ofexcessive deposition of periosteal bone by the unchecked activity of
osteoblasts.osteoblasts.
SOURCE:SOURCE: http://weeksmd.com/2009/11/vitamin-abeta-carotene-a-ok-by-me-a-review/http://weeksmd.com/2009/11/vitamin-abeta-carotene-a-ok-by-me-a-review/
A O f f S i lA OK f I f S i l
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A OK for Infant SurvivalA OK for Infant Survival
A study (N=15,000 infants) demonstrating 34% fewer death in the vitamin AA study (N=15,000 infants) demonstrating 34% fewer death in the vitamin Asupplemented group. Author Dr. Sommer reports: Thats when all the knives andsupplemented group. Author Dr. Sommer reports: Thats when all the knives and
spears came out, he says, relishing the memory. Finally in 1985, after deigning to dospears came out, he says, relishing the memory. Finally in 1985, after deigning to do
a patently unethical double-blinded placebo controlled study where 15,000 childrena patently unethical double-blinded placebo controlled study where 15,000 children
received vitamin A and 15,000 unfortunate other (doomed?) infants were given areceived vitamin A and 15,000 unfortunate other (doomed?) infants were given a
placebo, his finding that the vitamin A group had experienced 30 percent fewerplacebo, his finding that the vitamin A group had experienced 30 percent fewer
deaths than the placebo group was considered persuasive. Sommer recounts theirdeaths than the placebo group was considered persuasive. Sommer recounts their
ultimate reaction: Its a famous phenomenon, like the stages of grief, he says. Firstultimate reaction: Its a famous phenomenon, like the stages of grief, he says. First
they ignored it. Then they got angry. Finally they say, We knew it all along. Whatthey ignored it. Then they got angry. Finally they say, We knew it all along. What
they didnt know, however, until Kozakova et al published in April 2003, was thethey didnt know, however, until Kozakova et al published in April 2003, was the
mechanism of action whereby vitamin A deficiency compromises mucosal barriersmechanism of action whereby vitamin A deficiency compromises mucosal barriers
and leads to diarrhea. [18] These researchers observed thatand leads to diarrhea. [18] These researchers observed that vitamin A deficiencyvitamin A deficiency
led to a strong reduction of certain enterocyte enzymatic activities, which inled to a strong reduction of certain enterocyte enzymatic activities, which in
turn precipitated a lethal dysbiosis with increased bacterial translocation andturn precipitated a lethal dysbiosis with increased bacterial translocation andconsequent diarrhea.consequent diarrhea.
Source:Source: http://weeksmd.com/2009/11/vitamin-abeta-carotene-a-ok-by-me-a-review/http://weeksmd.com/2009/11/vitamin-abeta-carotene-a-ok-by-me-a-review/
Corrective Protocols
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for Common Ailments (cont.)
Cancer
Hepatitis
Multiple Sclerosis
IV Alpha Lipoic acidAlpha Lipoic acid
200mg/ml200mg/ml
add 1, 2, 3 cc toadd 1, 2, 3 cc to
250cc nl saline250cc nl saline
Side- Effects:Side- Effects:
hypoglycemiahypoglycemia
Corrective Protocols
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for Common Ailments (cont.)
Cancer
Hepatitis
Multiple Sclerosis
IV Ultraviolet BloodUltraviolet Blood
Irradiation (UBI)Irradiation (UBI)
Side- Effects: flu-Side- Effects: flu-
like symptoms,like symptoms,
Herksheimer (dieHerksheimer (die
off ) reactionoff ) reaction
Corrective Protocols
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for Common Ailments (cont.)
Cancer
Hepatitis
Multiple Sclerosis
SIVP Glutathione 200-Glutathione 200-
600mg600mg
Side-Effects:Side-Effects:
hypoglycemiahypoglycemia
(sweating)(sweating)
Corrective Protocols
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for Common Ailments (cont.)
Cancer Insulin Potentiated
Chemotherapy
(IPT) using
Always with oralHaelan 951
to address cancer
stem cells
1/10th of theconventional dose ofchemotherapy drug
Side-Effects:Side-Effects:
hypoglycemiahypoglycemia
(sweating)(sweating)
C St di P t t C t 4C St di P t t C t 4
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Case Studies: Prostate Cancer, stage 4Case Studies: Prostate Cancer, stage 4
64 yr old man, former competitive golfer,
DX: prostate cancer with edema mets to bone and lymphatic
congestion,
SX pain and restricted range of motion, not able to golf
PET/CT Bone Scan extensive metastasis
CCC with IPT 6 treatments
No pain after 1st
treatment, shrinking of edema, able to golfFollow-Up PET/CT after 10 treatments: near complete
resolution of lesions noted in prior study
Case Studies: LungCase Studies: Lung andand Breast CancerBreast Cancer
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Case Studies: Lungg and Breast Cancer
ID: 51 yr old woman
SX: unable to breath, difficulty walking, PET/CT: lesion in left lower lube lung bone lesion
Rx CCC with IPT (Vinorelbine 10mg Topotecan 4mg)over 6 weeks with
Ultraviolet Blood Irradiation (UBI) and high-dose vitamin C
(100gm) with high-dose alpha lipoic acid (ALA) 400mg andoral Haelan 951 4 oz twice a day away from food.
Resolution of breathing difficulty, able to walk with family
PET / CT: mass previously seen in posterior aspect of left
upper lung is no longer present No evidence of residualmediastinal lymphadenopathy compared to prior study, no
residual bone lesions no evidence of malignancies
Case Studies: Breast CancerCase Studies: Breast Cancer ID: 69 yr old woman
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ID: 69 yr old woman
Sx pain in right breast, fatigue, anxiety, fear.
Lab: triple negative (ER, HER2/Nu , BRCA 1 and 2 - tumor
suppressor genes ); Chemosensitivity testing www.biofocus.de
Rx: CCC with IPT (Cytoxan 75mg Docetaxel 15mg Vincristine
1mg ) over 8 weeks with Ultraviolet Blood Irradiation (UBI) and high-
dose vitamin C (100gm) with high-dose alpha lipoic acid (ALA)
400mg and oral Haelan 951 4 oz twice a day away from food. Result: increased energy, no pain, no fear
PET/CT after 6 weeks of CCC and IPT:
1) No evidence of residual metabolically active tumor in right breast.
2) No evidence of local regional or distant metastases.
C St diCase St dies: Hodgkins L mphoma
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Case Studies:Case Studies: Hodgkins Lymphoma
ID: 65 yr old man Sx: fatigue and cough (tumor pushing against trachea)
Lab: PET/CT
Rx: CCC with IPT
Result: two episodes of COMPETE resolution of tumor with
PET/CT but each time, patient STOPPED taking HAELAN
without notifying me and each time the tumor returned.
Patient is currently on 3rd course of treatment and promises he
will now be compliant with the protocol.
Case Studies: Breast Cancer stage 4Case Studies: Breast Cancer stage 4
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gg
ID: 61yr old woman
Sx: pain and fear, Lab PET/CT
Rx CCC with IPT (Doxorubicin 6mg 5-FU 100mg Cytoxan
100mg) with Haelan 951 and High dose Vit C and Alpha
Lipoic acid. Result: in 8 weeks (8 treatments) , no pain, no lump
PET/CT
1) No evidence of metabolically active tumor in left breast
or axilla. No rib cage involvement .
2) No evidence of local regional or distant metastases.
Summary of Case Study Findings
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Summary of Case Study Findings
1) IPT in the context of Corrective Cancer Care is well tolerated,effective and cost effective.
2) Always give Haelan 951 (or other stem cell redifferentiation agent)
along with chemotherapy
3) Antioxidants and immune enhancing protocols do not interfere with
IPT but rather enhance benefit and are protective of healthy cells and
vitality.
4) Patients find the experience not unpleasant (aside from the
therapeutic moment of low blood sugar).
5) Rare side effects: 2 of 100 with hair loss and rare nausea
Patients call it: Side-effect free effective chemotherapy !
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Summary and InvitationSummary and Invitation
to my esteemedto my esteemedJapanese colleagues!Japanese colleagues!
Join me in offering patientsJoin me in offering patients
Corrective Cancer Care Corrective Cancer Care
withwithInsulin Potentiation TherapyInsulin Potentiation Therapy
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The Standard of Care is sub-optimal.The Standard of Care is sub-optimal.
Survey result: Only 10% of conventionalSurvey result: Only 10% of conventional
oncologists say they would take theoncologists say they would take the
medication they prescribe if theymedication they prescribe if theythemselves had cancer.themselves had cancer.
In contrast, 100% of IPT doctors wouldIn contrast, 100% of IPT doctors wouldtake their own medicine!take their own medicine!
C ti C C ith IPTCorrective Cancer Care with IPT tt
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Corrective Cancer Care with IPTCorrective Cancer Care with IPT cont.cont.
Smart Bomb effect:Smart Bomb effect: Excess of insulin-Excess of insulin-sensitive receptors on human cancersensitive receptors on human cancer
cells causes predominance of insulincells causes predominance of insulin
effect in cancer cells, sparing normaleffect in cancer cells, sparing normalhost tissues =host tissues = INCREASED SAFETYINCREASED SAFETY
Synergy of insulinSynergy of insulins membrane and metabolics membrane and metaboliceffects enhances anticancer drug action ineffects enhances anticancer drug action in
cancer cells =cancer cells = INCREASED EFFICACYINCREASED EFFICACY
ff
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Why we offer beyond the standardWhy we offer beyond the standard
of care therapies?of care therapies?
1) more effective treatment1) more effective treatment
2) more grateful patients2) more grateful patients
3) more personal and professional3) more personal and professional
satisfactionsatisfaction
Corrective Cancer Care with IPTCorrective Cancer Care with IPT
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SafeSafeEffectiveEffective
Cost-effectiveCost-effective
andand
The longest continuous cancerThe longest continuous cancer
chemotherapeutic protocol in thechemotherapeutic protocol in the
western hemisphere (1926-present)western hemisphere (1926-present)
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"I die by the help of"I die by the help oftoo many physicians."too many physicians."
Alexander the GreatAlexander the Greaton his deathbed,on his deathbed, 323 B.C.323 B.C.
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WELCOME TO VISIT US IN SEATTLE !