intro to dental pain

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1 Dental Pain  Aims & Objectives  Aim - To introduce theories of pain and pulpal sensitivity Objectives - By the end of the lec ture you should be able to: Outline the embryology of the dental pulp Describe the theories of dentinal sensitivity with reference to anatomy of the pulp See the relevance of the hydrodynamic theory to operative dentistry Suggest what modifies perception of pain Determine which nerves are being stimulated causing dental pain Pain an unpleasant and emotional experience associated with actual or potential tissue damage or described in terms of such damage Presentation of pain Can you see it? Organic damage Psychological damage Interaction of these Trauma (eg. hot/cold, physical) Pain Misdirection: Focussed activity/Hy pnosis Reducing factors Concentration: Expectation/ Anxiety Increasing factors TENS

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8/4/2019 Intro to Dental Pain

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Dental Pain

 Aims & Objectives

 Aim - To introduce theories of pain and pulpal

sensitivity Objectives - By the end of the lecture you should be

able to: Outline the embryology of the dental pulp

Describe the theories of dentinal sensitivity with reference toanatomy of the pulp

See the relevance of the hydrodynamic theory to operative

dentistry

Suggest what modifies perception of pain

Determine which nerves are being stimulated causing dentalpain

Pain

an unpleasant and emotionalexperience associated with actual orpotential tissue damage or described interms of such damage

Presentation of pain

Can you see it?

Organic damage

Psychological damage

Interaction of these

Trauma (eg. hot/cold, physical)

Pain

Misdirection:

Focussed activity/Hypnosis

Reducing factors

Concentration:

Expectation/ Anxiety

Increasing factors

TENS

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Where does the dental pulpcome from? Layers

Ectoderm

Mesoderm

Endoderm

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Gut

NeuralTube

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The dentine-pulp complex

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Theories of dentinal sensitivity

Innervation of tubules

Synaptic junction with odontoblast

Hydrodynamic theory

Nerve fibrils are in the tubulesTheory 1

Theories of dentinal sensitivity

Innervation of tubules

Synaptic junction with odontoblast

Hydrodynamic theory

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Anastamosis with odontoblastTheory 2

Theories of dentinal sensitivity

Innervation of tubules

Synaptic junction with odontoblast

Hydrodynamic theory

Hydrodynamic theory

Gysi 1900

Brännström et al 1967

Cold – outward flow: aspiration & lessshearing forces

Hot – inward flow

 Alfred E Gysi

1865-1957

Fluid movement in tubulesTheory 3

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Nerves

 A-β

 A-δ myelinated

C (0.2-1.0μm) respond to mediators of inflammation)

Mechanism of dentinal fluid flow

Fluid outflow

Increased byinflammation/neuropeptides

Decreased by

 Albumin, globulins, fibrinogen

Fluid flow and pain

18.1 pLs-1mm-2

Normal physiological flow

1.0-1.5 nLs-1mm-2

Threshold for pain sensation (50x normal)

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Sensation from the pulp

Few proprioceptive fibres – body finds it

difficult to localise Hot/cold/tingle

Pain or no pain

Fluid flow in teeth

Poiseuille-Hagen equation

 V = π ΔP r4

8η l

V= volumeP= pulpal pressure

r = tubule radiusl = tubule length

η= viscosity of fluid

Pashley (1989) Scanning Microsc 3 161-176

Pulpal Pressure

Increased in inflammation

Decreased with local containingadrenaline

Tubule morphology

Pulpenamel 0.8μm 3μm

Fluid flow in teeth

Tubule radius0.8 - 2.5µm (EDJ - pulp)

(anatomical. Functional diameter5-10%)

Pulpal pressure

15cm H2O - 36cm H2O (low-high)

Fluid viscosity

Decreases from pulp to EDJ

Michelich et al (1978) J Dent Res 57 1019-1024Gerzina and Hume (1995) J Dent Res 74 369-373

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Cavity ½ dentine depth

If we assume viscosity and pulpal

pressure remain constant relative tofluid flow at EDJ :

Radius increases x16

Length of tubule x0.5

Fluid flow increases x32

Cavity ¾ dentine depth

If we assume viscosity and pulpal

pressure remain constant relative tofluid flow at EDJ:

Radius increases x256

Length of tubule x0.25

Fluid flow increases x1024

Tubules

Density varies between and within teeth

≈ 75,000 mm-2 coronally

≈ 30,000 mm-2 mid-root

Surface area of dentine made up of tubules

1% at EDJ

22% at pulp

Schellenberg et al  (1992) J Endod 18 104-109

Pashley (1989) Scanning Microsc 3 161-176