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INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEM CELL TRANSPLANTATION IN L Y MPHOMA Udine, October 19-20-21, 2005 Castello di Udine, Italy - Centro Congressi, Udine Fiere Presidents: Michele Baccarani Paolo Corradini Renato Fanin PROGRAM

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Page 1: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

I N T E R N A T I O N A L S Y M P O S I U M O N

ALLOGENEICSTEM CELLTRANSPLANTATIONIN LYMPHOMA

Udine, October 19-20-21, 2005Castello di Udine, Italy - Centro Congressi, Udine Fiere

Presidents:Michele BaccaraniPaolo CorradiniRenato FaninPROGRAM

Page 2: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

ORGANIZERS• Clinica Ematologica, DIRM,

University of Udine• Istituto di Ematologia ed Oncologia Clinica

L. e A. SeragnoliUniversity of Bologna

• Divisione di Ematologia,Istituto Nazionale per lo Studio e la Cura dei TumoriUniversity of Milan

SCIENTIFIC SECRETARIATFrancesco Zaja,Francesca Patriarca,Alessandra SperottoClinica Ematologica,P.zza S. Maria della Misericordia,33100 Udine, ItalyPhone + 39 0432 559662Fax + 39 0432 [email protected]

ORGANIZING SECRETARIATStudio E.R. CongressiGruppo TriumphVia Marconi 3640122 Bologna ItalyPhone + 39 051 4210559Fax + 39 051 [email protected]

Page 3: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

I N T E R N A T I O N A L S Y M P O S I U M O N

ALLOGENEICSTEM CELLTRANSPLANTATIONIN LYMPHOMA

Franco Aversa Perugia, ItalyMichele Baccarani Bologna, ItalyAndrea Bacigalupo Genova, ItalyTiziano Barbui Bergamo, ItalyPhilip J. Bierman Omaha, USAJan J. Cornelissen Rotterdam, The NetherlandsPaolo Corradini Milano, ItalyGiorgio Deliliers Lambertenghi Milano, ItalyPeter Dreger Hamburg, GermanyBrunangelo Falini Perugia, ItalyRenato Fanin Udine, ItalyJohn G. Gribben London, United KingdomKoi Izutsu Tokyo, JapanIssa F. Khouri Houston, USAJohn E. Levine Ann Arbor, USADavid G. Maloney Seattle, USAMassimo F. Martelli Perugia, ItalyEmma Morris London, United KingdomMichael Pfreundchuh Homburg/Saar, GermanyFranco Quadrifoglio Udine, ItalyStephen P. Robinson London, United KingdomNorbert Schmitz Hamburg, GermanyShimon Slavin Jerusalem, IsraelDavide Soligo Milano, ItalyRainer Storb Seattle, USACorrado Tarella Torino, ItalySante Tura Bologna, ItalyKoen van Besien Chicago, USALeo F. Verdonck Utrecht, The Netherlands

FACULTY

Page 4: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

october 19, 20054.45 p.m. REGISTRATION5.15 p.m. WELCOME ADDRESS FROM THE AUTHORITIES

LECTURESChairmen: F. Quadrifoglio - M. Baccarani

5.30 p.m. Treatment of non-Hodgkin lymphomas:do we need to improve the resultsof conventional therapies?M. Pfreundchuh

6.15 p.m. From preclinical models to clinical trials:background and rationale of RIC transplantS. Slavin

7.30 p.m. WELCOME COCKTAIL

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october 20, 2005GENERAL SESSIONChairmen: A. Bacigalupo – T. Barbui

8.30 a.m. Stem cell transplant in lymphomas:status of art, indications and choice of transplantR. Fanin

9.00 a.m. Identification of new lymphoma-associated molecules:an integrated antibody/proteomic/gene microarray approachB. Falini

9.30 a.m. Experimental and clinical evidenceof graft versus lymphoma effectJ.G. Gribben

10.00 a.m. From high dose therapy to RICR. Storb

10.30 a.m. COFFEE BREAK

LOW-GRADE LYMPHOMA SESSIONChairmen: I.F. Khouri – C. Tarella

11.00 a.m. Follicular lymphoma:results with conventional allogeneic transplantsK. van Besien

11.30 a.m. Follicular lymphoma: results with RIC transplantsI.F. Khouri

12.00 A.m. Mantle-cell lymphoma:is there a role for allogeneic transplants?D.G. Maloney

12.30 a.m. Chronic lymphocytic leukemia:indications for transplant and conditioning optionsP. Dreger

1.15 p.m. LUNCH

Page 6: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

october 20, 2005

HIGH-GRADE LYMPHOMA SESSIONChairman: R. Fanin - M. Pfreundchuh

2.30 p.m. Diffuse large B-cell lymphoma:results with conventional allogeneic transplantsL.F. Verdonck

3.00 p.m. Diffuse large B-cell lymphoma results with RIC transplantsS.P. Robinson

3.30 p.m. Peripheral T-cell lymphoma:salvage treatment with RIC transplantsP. Corradini

4.00 p.m. COFFEE BREAK

ROLE OF ALLOGENEICTRANSPLANTS IN HODGKINAND RARE LYMPHOMASChairmen: N. Schmitz - L.F. Verdonck

4.30 p.m. Hodgkin’s lymphomaN. Schmitz

5.00 p.m. Cutaneous T-cell lymphomaD. Soligo

5.30 p.m. Lymphoblastic/Burkitt lymphomaJ.E. Levine

6.00 p.m. How to monitor and treat EBV-relatedlymphoprolipherative disordersJ.J. Cornelissen

Page 7: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

october 21, 2005

8.00 a.m. selected ORAL communicATIONsChairmen: J.G. Gribben - G. Lambertenghi Deliliers

10.00 a.m. COFFEE BREAK

ALLOGENEIC TRANSPLANTATION:ALTERNATIVE DONORSAND GVHD PREVENTIONChairmen: S. Tura - M.F. Martelli

10.30 a.m. Which is the best stem cell source:syngeneic, sibling or unrelated donors?P.J. Bierman

11.00 a.m. Results with unrelated donor transplantK. Izutsu

11.30 a.m. Results with haploidentical donor transplantF. Aversa

12.00 a.m. Role of monoclonal antibodiesin GVHD prevention and treatmentE. Morris

Page 8: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

scientificinformationOral communicationsA plenary session is devoted to oral communications. Eight communicationswill be selected among those received. All received abstracts will be publishedon the Proceedings’ Book.Abstracts should be submitted within August 31, 2005 by e-mail to theOrganizing Secretariat Studio E.R. Congressi, Francesca Del Giudice e-mail:[email protected].

LanguageThe official conference language is English.No simultaneous translation will be provided.

BadgeAll registered participants, speakers and attendants will be given a badge whichthey must wear to be admitted to the scientific sessions.

SlidesSlide must be in English. Computer videoprojection will be available. Otherrequirements should be communicated to the Organizing Secretariat as soon aspossible. Slide should be handed to the slide center on floppy, cd-rom or pendrive one hour before the beginning of the session and collected at the end.

Attendance certificateA certificate will be given to all participants at the end of the conference.

ECMApplication for ECM credits will be made.

CHANGESParts of the programme may be changed if necessary.

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generalinformationConference venueVia Cotonificio, 9633030 Torreano di MartignaccoUdine- Italy

How to reach conference venueBy car:• A4 Venezia - Trieste

exit from the motorwayat Udine Sud

• A23 Udine - Tarvisioexit from the motorwayat Udine Nord

By bus from railway station:• bus n. 9 S-D

Page 10: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

generalinformationREGISTRATION FEE (in Euro - VAT included)Euro 100,00

The registration fee includes:• Conference kit• Proceedings’ book• Attendance certificate• Participation in the Scientific Sessions• Coffee-breaks and lunch• Welcome cocktail

REGISTRATIONRegistration can only be accepted and confirmed after the registration formand fee have been received by the Organizing Secretariat Studio E.R. CongressiGruppo Triumph. All payments must be done in Euro net of all bank charges andmade out to Studio E.R. Congressi S.r.l.

Please pay by• Eurocheque or Foreign Cheque• Bank transfer made out to Studio E.R. Congressi Srl

Account n. 000000002596-Cassa di Risparmio di Cesena-Agenzia n.29Largo Caduti del Lavoro 1/A, 40122 Bologna, ItalySwift code CECRIT 2C IBAN IT36J – ABI 06120 – CAB 02400 – CIN J

• Credit card

Please send a copy of the bank transfer with the registration form.

travel agencyCisalpina ToursVia Marconi, 4740122 Bologna - ItalyTel. +39 051 235783Fax +39 051 231640E-mail: [email protected]

Page 11: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

registrationform

Please, return this form to:

STUDIO E.R. CONGRESSI - GRUPPO TRIUMPHVia Marconi 36 - 40122 Bologna BO Italy

Phone +39 051 4210559 - Fax +39 051 4210174e-mail: [email protected]

LAST NAME

FIRST NAME

INSTITUTION/DEPARTMENT

INSTITUTION ADDRESS

PROFESSION

DISCIPLINE

PHONE FAX

MOBILE PHONE E-MAIL

PRIVATE ADDRESS

ZIP CODE PROVINCE

TAX PAYER’S NUMBER

FOR THE INVOICE:

LAST NAME

FIRST NAME

ADDRESS

CITY STATE/PROVINCE

ZIP COUNTRY

VAT NUMBER (P. IVA)

TAX PAYER’S NUMBER (COD. FISCALE)

ALLOGENEIC STEM CELL TRANSPLANTATION IN LYMPHOMA

Page 12: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

REGISTRATION FEES (in Euro - VAT included): € 100,00

PAYMENT❐ I enclose Eurocheque or Foreign Cheque

of Euro NumberBankmade out to Studio E.R. Congressi S.r.l.

❐ Bank transfer made out to Studio E.R. Congressi SrlAccount n. 000000002596-Cassa di Risparmio di Cesena-Agenzia n.29Largo Caduti del Lavoro 1/A, 40122 Bologna, ItalySwift code CECRIT 2C IBAN IT36J – ABI 06120 – CAB 02400 – CIN J

❐ Credit Card:Number ���� ���� ���� ���� Expiry dateOwner Date of birth❐ VISA ❐ MASTERCARD ❐ DINERS ❐ AMERICAN EXPRESS

I enclose a copy of the bank transfer with the registration form.

Registrations can only be accepted and confirmed when the registration formand fee have been received by the Organizing Secretariat Studio E.R. Congressi.In case of written cancellation before June 30th, 2004, 80% of the registrationfee will be refunded.

Signing this form and well informed on the legislative decree n. 196/2003 concerning "personaldata processing" - particularly on the articles 4, 13, 21, 23, 24, 27, 37, 43, 44, 45 e 137 - I autho-rize Studio E.R. Congressi S.r.l. until written revocation to process and divulge my personal datawithin the limits of the above mentioned legislative decree and in accordance with the procedu-re laid down by the legislative decree. I give my assent provided that Studio E.R. Congressi S.r.l.complies with the regulations in force.

❐ I do not want that my personal data are divulged to third parties.

Date Signature

ALLOGENEIC STEM CELL TRANSPLANTATION IN LYMPHOMA

Page 13: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

ALLOGENEIC STEM CELL TRANSPLANTATION IN LYMPHOMA

LAST NAME

FIRST NAME

ADDRESS

CITY STATE/PROVINCE

ZIP CODE COUNTRY

PHONE FAX

E-MAIL

NAME OF THE ACCOMPANYING PERSON

FOR THE INVOICE:

LAST NAME

FIRST NAME

ADDRESS

CITY STATE/PROVINCE

ZIP COUNTRY

VAT NUMBER / TAX PAYER’S NUMBER

hotel registration form

Please, return this form before July 31st, 2005 to:

CISALPINA TOURS Via Marconi, 47 - 40122 Bologna, Italy

Tel. +39 051 235783 - Fax +39 051 231640E-mail: [email protected]

Page 14: INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL · INTERNATIONAL SYMPOSIUM ON ALLOGENEIC STEMCELL TRANSPLANTATION IN LYMPHOMA Franco Aversa Perugia, Italy Michele Baccarani Bologna,

HOTEL CATEGORIES AND PRICESCATEGORY SINGLE DOUBLE SINGLE USE DOUBLE

MIN. MAX. MIN. MAX. MIN. MAX.

★★★★ € 100,00 € 102,00 € 100,00 € 114,00 € 130,00 € 150,00

★★★ € 65,00 € 70,00 € 75,00 € 78,00 € 108,00 € 111,00

Prices are expressed in Euro, per room, per night breakfast, services, 10% vat included.For each booked room, booking fee is of 10 Euros.

HOTEL RESERVATION❐ 4 stars ❐ 3 stars❐ Single ❐ Double ❐ Double single use

DATE OF ARRIVAL DATE OF DEPARTURE NIGHTS NUMBER

In case of double room, indicate the name of your room-mate

PAYMENT❐ I enclose Eurocheque or Foreign Cheque

of Euro Number

Bankmade out to Cisalpina tours SPA

❐ Bank transfer - All payments must be made in Euro and made out to Cisalpina Tours spaBANCA SAN PAOLO IMI (AGENZIA 14 - TORINO) – ABI 01025 – CAB 01014C/C 100000014885 – CIN P - IBAN: IT69P0102501014100000014885-BIC:IBSPITTM

❐ Credit Card:❐ VISA ❐ MASTERCARD ❐ DINERS ❐ AMERICAN EXPRESS

Credit Card Nr Expiry DateIn case of cancellation or no-show I authorize Cisalpina Tours Spa to debit my credit card for the amount due, as per cancellation policy.

Cardholder’s name Cardholder’s signature(Signature is valid as authorization)

ATTENTION: Please enclose a copy of the bank transfer with the registration form. In caseof written cancellation before September 10, 2005,80% of the registration fee will berefunded.After this date, the total amount will be charged.

Signing this form and well informed on the legislative decree n. 196/2003 concerning "personaldata processing" - particularly on the articles 4, 13, 21, 23, 24, 27, 37, 43, 44, 45 e 137 - I autho-rize Studio E.R. Congressi S.r.l. until written revocation to process and divulge my personal datawithin the limits of the above mentioned legislative decree and in accordance with the procedu-re laid down by the legislative decree. I give my assent provided that Studio E.R. Congressi S.r.l.complies with the regulations in force.

❐ I do not want that my personal data are divulged to third parties.

Date Signature

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Information onlegislative decree n. 196/2003

According to art. 13, Legislative decree no. 196/2003, and in relation to the processing of personal data, Triumph Viaggi & IncentiveS.r.l and Studio E.R. Congressi Srl inform you of the following:

l. Data processing purposesYour personal data will be processed by Triumph Viaggi & Incentive S.r.l. and Studio E.R. Congressi Srl for managing, accounting, sta-tistical, commercial, marketing and/or promoting purposes and this by processing, comparing, divulging or employing these very data.

2. Data Processing modalityData will be processed by appropriate devices ensuring their security and confidentiality. Data could be also processed by automaticmachines employed to process, store and transmit the very data.

3. Obligatoriness of personal data bestowalTo be registered in the congresses we organize, you are obligated to give your data.

4. Data communication, diffusion and transferYour data can be given to organizers of the congress and to the companies sponsoring the event as well as to other companies, autho-rities, consortia or associations that could divulge these data to their members, users and other related people within the limits of theirinstitutional purposes. The only objective is to inform the person concerned about the existence of similar initiatives or to supply himwith other information that could be deemed interesting.Furthermore, the above mentioned data can be given/divulged to companies, authorities, consortia and association working in Italy orin the EC countries having the same objectives as stated before.

5. Rights of interested partiesYou have the right to know, consulting the register specified in the art. 154 sub-section 1 letter l) of the legislative decree 196/2003, theexistence of data processing; you can partially or entirely oppose, for legitimate reasons, the processing of your data, even if these dataare relevant to the objective of data collection. Furthermore you can prevent his data from being used for commercial purposes, marketsurveys, advertisement for direct selling or interactive commercials.You are acknowledged exercise of rights as per art. 7, Legislative decree 196/2003, the complete text of which is given in the enclosure.

6. The owner of the data processing The owners of the data processing are Triumph Viaggi & Incentive S.r.l Via Lucilio, 60 - 00136 Roma and Studio E.R. Congressi Srl, viaMarconi 36, 40122 Bologna. The list of the people responsible of the processing itself is kept updated, and you can easily consult it sen-ding a written communication to the above address.Data will be held into the Triumph Viaggi & Incentive S.r.l and Studio E.R. Congressi Srl buildings, as long as the law prescribes.

Article 7 of the legislative decree 196/2003 – right of access to personal data and other rights

1. The person concerned has the right to obtain confirmation of the existence of personal data and information regarding him/her – eventhough not recorded yet – and their disclosure under an intelligible form.

2. The person concerned is entitled to be informed of: a) the origin of personal data and information; b) data treatment purposes and ways; c) the logic followed in the event of data treatment being carried out with electronic tools; d) the details to identify the owner, the persons in charge and the representative appointed under article 5, paragraph 2; e) the people or groups of people to whom personal data and information can be disclosed or who may come to know them in their

capacity as representative appointed in the State territory or persons in charge.

3. The person concerned has the right to obtain: a) updating, correction or – where interested in this process – supplementation of data; b) cancellation, turning into anonymous data or the block of data treated by infringing the law, including data and information which

need not be kept in relation to the purposes for which data and information were collected or subsequently treated; c) a certificate stating that the operations under sub-paragraphs a) and b) - including their content – have been communicated to

those to whom data and information were provided or disclosed, except the case when this proves to be impossible or entails theuse of such an amount of means which is overtly non commensurate with the right which is protected.

4. The person concerned has to right to wholly or partially refuse: a) treatment of personal data and information regarding him/her for legitimate reasons, even though they are relevant to the aim of

collection; b) treatment of personal data regarding him/her for the purposes of sending advertising material, direct sale or performance of mar-

ket studies or commercial communications.

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ORGANIZING SECRETARIATStudio E.R. CongressiGruppo TriumphVia Marconi 3640122 Bologna ItalyPhone + 39 051 4210559Fax + 39 051 [email protected]

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