Conference Chair | Laurence Klotz, MD

Meeting Room: Ballroom B Hanra - Level 3F

WELCOME & INTRODUCTIONS

Meet and Greet International Colleagues (coffee and refreshments served)

Framing of Theme | Laurence Klotz

ALL TALKS 10 MINUTES FOLLOWED BY 2 MINUTE Q & A

SESSION ONE | PROSTATE CANCER SCREENING & PREVENTION | Co-Moderators: Ji Youl Lee &

Laurence Klotz

Prostate Cancer Screening: European Perspective | Franz Recker, MD

Prostate Cancer Screening: American Perspective | Matthew Cooperberg

Prostate Cancer Screening: Japanese Perspective | Shin Egawa

Prostate Cancer Prevention, Statins and Omega 3 | Vincent Fradet, MD

FSH and Prostate Cancer | Jehonathan Pinthus, MD

DISCUSSION (10 mins) DISCUSSION (10 mins)

SESSION TWO | PROSTATE CANCER MANAGEMENT OPTIONS | Co-Moderators: Thomas Keane &

Sung Kyu Hong

CASE & DEBATE – MANAGEMENT OF GRADE GROUP 2 PROSTATE CANCER

9:15 Surveillance | Sung Kyu Hong, MD

9:25 Focal Therapy | Raphael Sanchez-Salas, MD

9:35 Radical Therapy | Neil Fleshner, MD

DISCUSSION (10 mins) DISCUSSION (10 mins)

Can Ultrasound Imaging Replace MRI? | Peter Hammerer, MD

Can MRI Replace Prostate Biopsy | Guillaume Ploussard, MH, PhD

Integrating Imaging and Biomarkers in Prostate Cancer Diagnosis | Derya Tilki, MD

DISCUSSION (10 mins)

SESSION THREE | UROTHELIAL CANCER | Moderator: Robert Siemens

Liquid Biopsy for Bladder Cancer Prognosis | Peter Black, MD

Impact of Urinary Marker Testing in Bladder Cancer Impact of Urinary Marker Testing in Bladder Cancer | Badrinath Konety, MD

Clinical Implications of Mutational Profi ling of Invasive Bladder Cancer | Seth Lerner, MD

Should Variant Histology Change Management of Bladder Cancer? | Ashish Kamat, MD

DISCUSSION (5 mins)

WORKING LUNCH

Complimentary Meal to All Seated Participants Attending Session Four Working Lunch

SESSION FOUR | TOWN HALL

EMERGING DIAGNOSTIC BIOMARKERS IN PROSTATE CANCER

| Moderator: Laurence Klotz

Introduction by Matthew Cooperberg, MD: The Unmet Need for Liquid Biopsy in the Diagnostic Pathway

INDUSTRY: EMERGING BIOMARKERS – WHAT IS THE LATEST DATA?

PANELISTS: | “BIOMARKERS IN PROSTATE CANCER”

Current Role of Molecular Biomarkers in the Management of Prostate Cancer: Which Ones and Why?

12:40 Panelist One I Shin Egawa

12:45 Panelist Two I Marc Dall’Era 12:45 Panelist Two I Marc Dall’Era

12:50 Panelist Three I Alexandre De La Taille

12:55 Panelist Four I Derya Tilki

OPEN DISCUSSION (30 mins) | Panelists & Industry Only

SESSION FIVE | PROSTATE CANCER TREATMENT OPTIONS | Co-Moderators: Damien Bolton & John Davis

Improving the Outcome of Men on Active Surveillance | Marc Dall’Era, MD

RP in Men Over Age 75: Is it Folly? | Shomik Sengupta, MD

Advances in MR-U/S Fusion Guided Advances in MR-U/S Fusion Guided | Art Rastinehad, MD

DISCUSSION (10 mins)

SESSION SIX | KIDNEY CANCER | Co-Moderators: Allesandro Volpe & Ofer Yossepowitch

Challenges in Cystic Renal Tumours | Makarand Khochikar, MD

Genetic Alterations in RCC–Clinical Implications | HJ Ahn, MD

Where to Draw the Line Between Radical and Partial Nephrectomy? | Peter Mulders, MD

Adjuvent Therapy in RCCPost Nephrectomy | Robert Flanigan, MD

DISCUSSION (10 mins) DISCUSSION (10 mins)

SESSION SEVEN | ADVANCED PROSTATE CANCER | Co-Moderators: Marcelo Bendhack

& Mark Frydenberg

Medical Tourism in Urologic Oncology: Korean Perspective | Ji Youl Lee, MD

PSMA in the Management of Patients with Biochemical Failure | Shrawan Singh, MD

Chemotherapy for CRP - Role in the Era of ARTs | Peter Black, MD

How To Reduce Errors in Scientifi c Research | Laurence Klotz, MD

DISCUSSION (10 mins)

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Asian-Pacific Society of Urologic Oncology

(APSUO)

Australian Urologic Oncology Section

British Association of Urologic Surgeons

- Urologic Oncology Section (BAUS)

Canadian Urological Oncology Group (CUOG)

Chinese Urologic Oncology GroupChinese Urologic Oncology Group

European Society of Urologic Oncology

German Society of Urological Oncology

Indian Urological Society

Israeli Society of Urologic Oncology

Italian Society of Urologic Oncology

Japanese Society of Urological Oncology

Korean Society of Urologic Oncology

Latin American Society of Urologic Oncology

Mexican Society of Uro-Oncology

Philippines Society of Urological Oncology (PSUO)

Peruvian Association for the Study of UrologicalPeruvian Association for the Study of Urological

Cancer (APECU)

Portuguese Genitourinary Uro-Oncological Group

Society of Urologic Oncology (North America) (SUO)

Turkish Urologic Oncology Society

Member Societies

Conference Chair:Laurence Klotz, MD

WUOF Chairman (Canada)

WUOF Steering Committee:

Peter Black, MD (Canada)Sung Kyu Hong, MD (Korea)Ji Youl Lee, MDJi Youl Lee, MD (Korea)Alessandro Volpe (Italy)

INTERNATIONAL ISSUES IN UROLOGIC ONCOLOGY

FACULTY & PARTICIPANTSAustralia Professor Damien M Bolton, MD, PhD, BA, MBBS, FRCS, FRACS Clinical Professor of SurgeryUniversity of Melbourne Olivia Newton-John Cancer and Wellness Centre Wellness Centre Austin Hospital, Melbourne

Mark Frydenberg, MD, MBBS, FRACS (Urology) Chairman President, Urological Society of Australia and New Zealand Professor, Department of Surgery Monash University Monash University Chairman, Department of Urology Monash Health Melbourne, Victoria, Australia

Shomik Sengupta, MBBS, MS, MD, FRACS General, Oncology & Minimally Invasive Urologic Surgeon Invasive Urologic Surgeon Professor of Surgery, Eastern Health Clinical School, Monash University Leader, Genitourinary Oncology Special Advisory Group, USANZ Glen Waverly, Victoria

Brasil Prof. Dr. Marcelo L. Bendhack Prof. Dr. Marcelo L. Bendhack Professor de Urologia HCV- UP Presidente Sociedade Latino Americana de Uro-Oncologia UROLA Clinica de Uro-Oncologia do Brasil Ltda. São Paulo | Curitiba | Brasil

Canada Peter Black, MD, FACS, FRCSC Peter Black, MD, FACS, FRCSC Khosrowshahi Family Chair Professor, UBC Department of Urologic Sciences Senior Research Scientist Vancouver Prostate Centre

Neil Fleshner, MD, MPH, FRCSC Professor of Surgery Professor of Surgery Martin Barkin Chair of Urology, University of Toronto Head, Division of Urology, University Health Network Love Chair in Prostate Cancer Prevention Princess Margaret HospitalPrincess Margaret Hospital

Vincent Fradet, MD, PhD, FRCSC Urologist oncologist, CHU de Québec —Université Laval Associate Professor, Department of Surgery, Université Laval Researcher, CHU de Québec Research Center Research Center Researcher, Cancer Research Center, Université Laval Researcher, Institute for Nutrition and Functional Foods (INAF), Université Laval

Laurence Klotz, MD, CM Professor of Surgery, Professor of Surgery, University of Toronto Chairman, WUOF Chairman, CURC Associate Editor, Journal of Urology Division of Urology Sunnybrook Health Sciences Centre

Jehonathan H. Pinthus, MD, PhDJehonathan H. Pinthus, MD, PhD Associate Professor Urologic Oncology Department of Surgery McMaster University

D. Robert Siemens, MD Professor and Chair Department of Urology Department of Urology Queen’s University Kingston, Ontario

Korea HJ Ahn

Sung Kyu Hong, MD, PhD Professor Department of Urology Seoul National University College of Medicine Medicine Seoul National University Bundang Hospital

Ji Youl Lee, MD Professor & Director, Department of Urology, Seoul St. Mary’s Hospital Director of Robotic Surgery Center, Seoul St. Mary’s Hospital Seoul St. Mary’s Hospital Vice-President of Research, Comprehensive Cancer Hospital, Seoul St. Mary’s Hospital Director of Catholic Cancer Research Institute President of Korea Prostate Bank Director of Catholic Prostate Institute Director of Catholic Prostate Institute

Switzerland Franz Recker

The Netherlands Peter Mulders, MD, PhD Professor and Chairman Department of Urology Radboud University Medical Centre Radboud University Medical Centre Nijmegen

United States of America Matthew R. Cooperberg, MD, MPH Associate Chair for Clinical Research Associate Professor, Departments of Urology, Epidemiology & Biostatistics Helen Diller Family Chair in Urology Helen Diller Family Chair in Urology University of California, San Francisco

Marc Dall’Era, MD Professor and Vice Chair Department of Urology University of California, DavisWith appreciation

John W. Davis, MD John W. Davis, MD Professor of Urology Director, Urosurgical Prostate Program MD Anderson Cancer Center Houston, Texas USA

Robert C. Flanigan, MDTBATBA

Ashish M. Kamat, MD, MBBSProfessor of Urologic Oncology (Surgery) Wayne B. Duddlesten Professor of Cancer Research Attending Surgeon, Department of Urology, Division of Surgery Urology, Division of Surgery The University of Texas, MD Anderson Cancer Center

Thomas E. Keane, MB, ChB, FRCSI, FACSProfessor and Chair Department of Urology Medical University of South Carolina

Seth P. Lerner, MD, FACS Seth P. Lerner, MD, FACS Professor, Scott Department of Urology Beth and Dave Swalm Chair in Urologic Oncology Director of Urologic Oncology Director of the Multidisciplinary Bladder Cancer Program Faculty Group Practice Medical DirectorFaculty Group Practice Medical DirectorCo-Editor in Chief Bladder Cancer Baylor College of Medicine Medical Center Houston, Texas

Art R. Rastinehad D.O. Associate Professor of Urology Radiology Director of Focal Therapy Radiology Director of Focal Therapy and Interventional Urologic Oncology Icahn School of Medicine at Mount Sinai New York, N

France Dr Guillaume Ploussard, MH, PhD Institut Universitaire du Cancer Toulouse - Oncopole / Saint Jean Languedoc Hospital Chairman, EAU-YAU Prostate Cancer Working Party Working Party

Rafael Sanchez Salas, MD Attending Surgeon, Department of Urology L’Institut Mutualiste Montsouris Paris, France

Pr. Alexandre de la Taille Chair, Department of Urology Chair, Department of Urology Director of INSERM team U955Eq07 Robotic and Miniinvasive Surgery Assistance Publique des Hopitaux de Paris CHU Mondor – Faculté de Médecine Créteil, France

GermanyGermanyProfessor Dr. Peter Hammerer Chairman Department Urology and Urooncology Academic Hospital Braunschweig Salzdahlumer Str. 90

Markus Grafen, MD Professor of Urology Professor of Urology Head, Martini-Klinik Prostate Cancer Center Hamburg, Germany

Christian Stief

Derya Tilki, MD Professor of UrologyMartini-Klinik Prostate Cancer Center Martini-Klinik Prostate Cancer Center and Department of Urology University Hospital Hamburg-Eppendorf Hamburg, Germany

India S.K. Singh M.S, M.Ch, FAMS Professor of Urology, Professor of Urology, Post Graduate Institute of Medical Education & Research, Chandigarh, India

Dr Makarand Khochikar MS DNB (Urol) Dip Urol (London) FRCS (Urol) FEBU Chief Uro-oncologist Chief Uro-oncologist Siddhi Vinayak Ganapati Cancer Hospital, Miraj (India) President Urological Society of India -West Zone Board of Directors SIU

IsraelOfer Yossepowitch Ofer Yossepowitch Professor of urology Chair, Department of urology Tel Aviv Sourasky Medical Center Tel Aviv, Israel

Italy Alessandro Volpe, MD Associate Professor of Urology Associate Professor of Urology University of Eastern Piedmont Maggiore

Japan Shin Egawa, MD Professor and Chairman, Department of Urology, Jikei University School of Medicine, Jikei University School of Medicine, Tokyo

www.uro-onco.org

October 4, 2018Seoul Dragon City Cheongpa-ro 20 Gil 95 Yongsan-guSeoul, South Korea, 04347