international atomic energy agency internal dosimetry software assessment of occupational exposure...

International Atomic Energy Agency

Internal Dosimetry Software

ASSESSMENT OF OCCUPATIONAL EXPOSURE DUE TO INTAKES OF

RADIONUCLIDES


Introduction


Internal dosimetry software

Internal dosimetry related calculations are complicated

Biokinetic models

Dosimetric models

Direct measurement system calibrations

Several software packages have been developed to assist the dosimetrist


Software is available for various tasks

Lookup tables Dose coefficients Retention fractions, etc.

Dosimetry calculations Intake Committed equivalent dose Committed effective dose


Dose Coefficients and Intake Fractions


Rad_toolbox

• Available, free of charge at http://ordose.ornl.gov/downloads.html

• This toolbox provides ready access to data of interest in radiation protection of workers and members of the public.

• Data include interaction coefficients for , e- , photon and n radiations, nuclear decay data, biological and physiological data, etc.

• Other supportive data include dose coefficients for intakes of radionuclides, for inhalation, ingestion for members of the public and workers.

• The ORNL TM report is included in the download.


Rad_toolbox

Dose coefficient workers ex ICRP 68


Rad_toolboxContains dose coefficients for single organs (committed equivalent dose) and Committed effective dose .

There is the possibility to transfer the values on an Excel file

Dose coefficients for workers


Rad_toolbox

Dose coefficients for members of the population


ICRP Database of Dose Coefficients

Contains dose coefficients from ICRP Publications 68 (Workers) and 72 (public), including organ doses

Inhalation of 10 different AMADs

10 different integration periods

Text of ICRP 68 and 72 with search function

Biokinetic models for all elements

Results can be saved as ASCII files and printed



Characteristics of output



On line help tool: Biokinetic model


C. Potter: Health Physics retention fraction CD

• Pathway : Only Inhalation

• Retention/ excretion curves in table form

• CD-ROM attached to HP Nov. 2002 issue, Vol. 83 n. 5

• Intake retention fraction for stable element for respiratory tract, 24h urine, 24h feces, accumulated urine and accumulated feces (useful for 3 day collection of feces) .

• Absorption Types F, M, S; 5 μm AMAD.

• No dose coefficients !


C. Potter: Health PhysicsIntake retention fraction


C. Potter: Health Physics retention fraction CD HP Vol 83, 5 Nov. 2002

Biokinetic model parameters


IAEA SRS 37

• Available, free of charge at www-pub.iaea.org/MTCD/publications/PDF/Pub1190/Pub1190_web.pdf

• Tables :www-pub.iaea.org/MTCD/publications/PDF/Pub1190/tables.pdf

• Characteristics• Pathway : Inhalation, ingestion, injection.

• Absorption types , F, M, S, V.

• AMAD = 1 and 5 μm.

• Vapors

• Tables in logarithmic intervals.


IAEA SRS 37

• Standard worker

• Sub-set of radionuclides present in ICRP 68


IAEA SRS 37

• Retention / excretion function (also skeleton organ)

• Dose coefficients for both inhalation, ingestion , injection.


DCAL

• Available, free of charge at http://ordose.ornl.gov/downloads.html

• DCAL is a comprehensive software system for the calculation of tissue dose and subsequent health risk from intakes of radionuclides or exposure to radionuclides present in environmental media.

• The system includes extensive libraries of biokinetic and dosimetric data and models representing the current state of the art.

• DCAL maybe used either in an interactive mode or in a batch mode and is intended for experienced users with knowledge of computational dosimetry.


DCAL


DCAL

Activity in organs

Rate of equivalent dose

in organs


DCAL

Committed organ doses and committed effective dose


Dose Calculation Software


Dose calculation software

Software that can be used to estimate intake and internal doses has been developed using various techniques for different applications

Table look-up Biokinetic and dosimetric modeling

Inhalation Inhalation or ingestion Single intake Multiple intake


MONDAL3

Available free of charge, on request at http://www.nirs.go.jp:8080/anzendb/RPD/gpmd.php


MONDAL3

Calculates intake and committed effective doses a point at a time.

Several radionuclides

Selection between Inhalation and ingestion

Selection between workers and members of the population

Mode of intake , acute, chronic, uneven chronic.

m(t) values up to 1000 days after intake

Radioinuclide available 3H, 32P, 51Cr, 54Mn, 59Fe, 57Co, 58,60Co, 65Zn, 86Rb, 85Sr, 89,90Sr, 95Zr, 106Ru, 110mAg, 124Sb, 125Sb, 125,129,131I, 134,137Cs, 140Ba, 141,144Ce, 203Hg, 226,228Ra, 228,232Th, 234,235,238U, 237Np, 238,239,240Pu, 241Am, 242,244Cm and 252Cf.

• Selection of AMAD = 0.1, 0.3, 1.0, 3.0, 5.0 e 10 µm for workers• = 1.0 µm for member of the population


MONDAL3 Uneven chronic intake


MONDAL3

m(t) value

Evaluated intake I = M / m(t)

E(50) = e(50) * IM = measurement value

Type of measurement

t = time of measurement


Integrated Modules for Bioassay Analysis IMBA

Development began in 1997 by the NRPB

Features modular structure, interacting via ASCII data sets

Implements latest ICRP biokinetic models

Fitting uses maximum likelihood method

Use data recorded a being less than some minimum detection level

Specify multiple intake regimes


IMBA

Each module developed independently by two separate organizations

Available in four different editions depending on included additional functions

Multiple intake regimes

Up to 30 associated nuclides

Simultaneous bioassay types


IMBA Professional Plus

Present status: IMBA Professional Plus


IMBA

Information available at www.hpa.org.uk/radiation/publications/software/imbapro_plus/index.htm


IMBA

Information


IMBA

Bioassay calculation


IMBA

Use of multiple data-set for unique evaluation via maximum likelihood

From Bioassay to intake From Intake to Bioassay


IMBA

Dose Calculations


AIDE AIDE (Activity and Internal Dose Estimates) is a software for

calculating activities in compartments and committed doses due to occupational exposures, and for performing intake and dose estimates using bioassay data

This software has been continuously developed and tested for more than twenty years.

Due to its extensive previous uses and challenges AIDE has proved to be suitable to all sorts of users, from beginners in internal dosimetry through its use in courses promoted by IAEA ARCAL (Harmonization of Internal Dosimetry Procedures (ARCAL

LXXVIII),) up to advanced users performing evaluations of dose reconstruction.


AIDE

This software comprises three basic parts, which will be briefly described below:

Activity and Internal Dose Calculations,

Bioassay Interpretation, and

Edit Models.


AIDE

Activity and internal dose calculations

It has the aim to calculate activities in compatments and committed doses due to occupational exposure for performing intake and dose estimates using bioassay data


AIDE

Bioassay interpretation , intake evaluation chi squared test for fitting, possibility to de-select bioassay values.


AIDE The Model Editing form: Possibility to edit

different model from default ICRP models


AIDE Detail of an original model: Source->Target

fractions and biological half lives

A demonstration of AIDE will be performed next week.

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IDEA - System

Developed as spin-off project of the Research Center Karlsruhe. Expert system. Based on IDEAS Guidelines.


Software Information Contacts

RAD_Toolbox

http://ordose.ornl.gov/downloads.html


http:// www.icrp.org

C. Potter. Intake retention fraction Health Physics

Sellers of Health Physics



DCAL


MONDAL3

http://www.nirs.go.jp:8080/anzendb/RPD/gpmd.php

IMBA

www.hpa.org.uk/radiation/publications/software/imbapro_plus/index.htm



IAEA SRS 37

http://www-pub.iaea.org/MTCD/publications/PDF/Pub1190/

Pub1190_web.pdf

DCAL


MONDAL3

http://www.nirs.go.jp:8080/anzendb/RPD/gpmd.php



IMBA

www.hpa.org.uk/radiation/publications/software/imbapro_plus/index.htm

AIDE

Rodolfo Cruz-Suarez at IAEA

IDEA-System

http://www.idea-system.com

international atomic energy agency internal dosimetry software assessment of occupational exposure...

Documents

toolbox dose coefficients

effective dose slide

equivalent dose

printed slide

dosimetrist slide

excel file dose coefficients

biokinetic model slide

interaction coefficients