innovation in sensor design:
DESCRIPTION
Innovation in Sensor Design: A Market Driven Approach for HEI Research & CommercialisationTRANSCRIPT
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Innovation in Sensor Design: A Market Driven Approach for
HEI Research & Commercialisation
Mohd. Murray HunterSME Unit
University Malaysia Perlis
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New Expectations
• Government’s New Bio-Technology Policy• Funding Focus on Applications/Potential
Commercialisation• Universities Becoming Commercially Orientated• Research Institutions Want Commercial Results• New Community Expectations• Focus on Agriculture• Peer Hopes and Expectations
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A New Paradigm Required To Meet Changing Expectations
• Emphasis Shifting to Development and Potential Applications
• Possible Commercialisation
• Research Funding Tied to Results/Outcomes
• Institution Questions –
Can it be Commercialised?
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This Requires a Change in Research Orientation
• What We Investigate?• How We Investigate?• Change in Outcome Objectives• Use Different Milestones• Use of Multidisciplinary Approach• Need to Consider Wider Issues• Less Projects – Longer Projects• Higher Degree of Collaboration
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World Trends
• There will be less funding from Government for R&D• More competition for R&D Funds• Cluster Development (Universities/Research
Institutes/Industry)• Industry Based Research• Move from Basic to applied, collaborative & contract
research• Rapid commercialisation in niche areas• Focus on IDS (Information Delivery systems)• Most International R&D Industry Collaborative
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THE EVOLUTION OFBIOSENSORS
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Enzyme Cell Micro-organism
Immuno-agent Animal/Plant
Tissue
Chemo-receptor
XXX XX X
Semi-conductor
(ISFET)
XX X
Thermo-metric
(Thermistors)
X X
Photometric
(optical Fibers)
X X
Plezo-electric
(Quartz)
X X
Chemo-mechanic
X
Biosensor
Transducer
ElectroChemical
cell
amperometric
potentiometric XXX XX
XX
X XXX
Classification of Biosensors with Respect of Biorecptor and transducer Employed
Source: Minh Canh. Tran Biosensors 1994
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Electrochemical Clinical DiagnosisPrimarily amperometric
Optical Still Based in Clinical Diagnosis
But expand to:•Environmental
•Food•Security
•Basic biological researchProtein Engineering
(Method & Design)
Cheaper through
mass manufacture
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The evolution of a number of SMEs in Europe,And the Asia-Pacific
“Revolutionized the management of diabetesAnd other important aspects of clinical diagnosis”
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Biosensors have been dominated by oneapplication
Dramatic changes last few years
Requires the need to cross disciplines andutilize new techniques
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Molecular Biology
New GenerationOf Sensors
Down to the Molecular LevelMore rugged Construction
ThermallyStable
Cheaper andMore rapid to
Produce
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Research & Development
• Traditionally Been Inspired by Individuals in Group or Institutional objectives
• Information Published or Disseminated at Conference/Seminar
• Work is Usually Forgotten
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Types of Research
• Pure Basic Research
• Experimental and theoretical work undertaken to acquire new knowledge without looking for long-term benefits other than the advancement of knowledge
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Types of Research
• Applied Research
• Original work undertaken primarily to acquire new knowledge with a specific application in mind
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Types of Research
• Strategic Basic Research
• Experimental and theoretical work undertaken to acquire new knowledge directed into specified broad areas that are expected to lead to useful discoveries
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Types of Research
• Experimental Development • Systematic work, drawing on existing
knowledge gained from research and/or practical experience, that is directed to producing new materials, products or devices, to installing new processes, systems and services, or to improving substantially those already produced or installed.
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Types of Research
• Collaborative Research
• research projects jointly developed by the university and the external partner
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Types of Research
• Contract Research
• request made by industry or government agency for a specified research project to be carried out with identified aims & objectives
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Types of Research
• Sponsored Research
• granting agencies advertise a call for applications and applications are normally peer reviewed. Research projects are normally basic or strategic but not normally concerned with commercial outcomes
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Types of Research
• Consultancy
• project involves buying the skills and expertise (background IP) of university staff, as well as infrastructure to work on a specified project
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Types of Research
• Demonstrative Research
• Seeks to answer a question or solve a problem from data collected, usually un-replicated, for the purposes of demonstrating a concept or process to a group, or a method, part of skill development or experiential learning
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Thus research will stem from
Basic Research
to
Applied, Collaborative, demonstrative &
Contract Research
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Idea from Research Institute, University faculty or individual within them
Undertake study with objectives interesting to researchers
Primarily single discipline approach
Objectives based on discipline thinking
Project results and conclusion
Publish
Paper at Conference
Add to CV
Little commercial interest:Private sector unaware
No or limited economic study or little consideration to scale up potentialNB: to bioprocess engineer has this as a fundamental consideration (difference between scientist and engineer)
Traditional Research Paradigm
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Competency and Strength of Research Institutes/Universities
Laboratory Results
Pilot Plant/Prototype
Industrial Scale
Technology Transfer
Research
Development
Commercialisation
Strong
Moderate/
Strong
Moderate/Weak
Investors expect complete technology transferR&D Institutes offer to development stage
Tan Sri Dr. Yusof Basiron, Commercialisation of R&D Outputs – MPOB Ex
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Typical Research Project Structure
Problem
Potential Applications of Technology
Basic Technologies
Collaborators ResourcesPotential
Product/Process Outcomes
Milestones/Expected Outcomes
Spin-Offs Downstream/Vertical
Market or Other Significance for Developed Application
Industry
Entrepreneurs
Research Institutions
Technology Needs
Solution
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A simple Market Driven Research Model
Industry defined problem or issue
Parameters of problem researched with reference to interdisciplinary frames
Theoretical solution thought out, becomes project objectives, with boundaries of industry requirements
Process designLaboratory trialScaling up
Industry implementation
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Research will resemble the basic steps in the product development process
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Steps in Commercialisation
• Identify problems that need to be solved a) social b) Industry c) existing d) New areas• Seek commercial collaboration from outset a) discuss potential needs b) what problems need to be solved? c) Market opportunities
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Steps in Commercialisation (Cont.)
• Adopt Market Driven Research Framework
• View Research in a Product Development Framework
• View Technology as a means to problem solving rather than an end (i.e., what basic technologies can be utilised?)
• Seek to develop a multidisciplinary team with industry representatives
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Technology State of the art and emerging technology Re-evaluating existing technology
Product Opportunity
Gap Economic State of the economy Shift in focus on where to spend money Level of disposable income
Social Social and cultural trends and drivers. Reviving historical trends
Cagan, J. and Vogel, C., M., (2002),
Many Factors Change Markets and Give rise to Opportunities
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Steps in Commercialisation (Cont)
• Once established technology, identify its benefit to particular applications
• Horizontal diversifications
• Focus on IDS (Information Delivery Systems) for user friendliness
• Protect IP
• Show off Potential applications where potential takers are
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Some Problems
• Finding out what the market requires is a skill that needs to be developed
• There may be no companies involved in a particular niche of an industry sector that we are interested in – This is another barrier to commercialisation in Malaysia
• Scientists are used to working in isolation to industry
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The Product Development Process
• Ideation
• Developing Product Specifications
• Market and Application Planning
• Concept and Prototype Generation
• Product Registration
• Product Design
• Further System Development
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Opportunity is a Construct
Ability to make linkagesAnchoring a source
of innovation
Having the right Skills
Networks
Resources
Product/MarketStrategy
VisionPlatform
Dream, ego, aspiration, greed, survival, education
ExperienceReference & Benchmark
Cognitive, hemispherial & field Perception
Source Explanation Examples
The unexpected success, failure or
external occurrence
Success of a revolutionary product or the application of technology from one industry to another, sudden or unnoticed demographic changes caused by wars, insurgencies, migration, etc.
Apple computerRapid decline of Proton’s market share
An incongruity between reality as it actually is and
what it ought to be
A change that is already occurring or can be made to occur within an industry. It may be visible to those inside the industry, often overlooked or taken for granted.
Sugar free products and sugar replacements due to concern for healthIncreasing demand for travel and holidays due to increasing incomes and leisure time
Inadequacy of an existing
technology or business process
An improvement in process that makes consumers more satisfied based on an improvement or change in technology.
Caffeine free productsMicrowave ovensMobile phones
Changes in industry or market
structure
New ways and means of undertaking business based on identified opportunities or gradual shifting of the nature of the industry.
Health care industryEducation industry – private education
Perceptual changes
Changes in peoples awareness founded on new knowledge and/or values or growing affluence leading to new fashions and tastes
Leisure and exercise industry aerobics & gyms
Demographic changes
Gradual shift of demographics in population by age, income groups or ethnic groups, etc
Establishment of more retirement homes
New knowledge New knowledge or application of existing theoretical knowledge into an existing industry that can create new products not previously in existence
Video and VCD industryRoboticsBiotechnology
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The Ideation Process
Definition: The process of conceptualizing a new
idea for manifestation into a new
product
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The Product Development Process
• Ideation
• Developing Product Specifications
• Market and Application Planning
• Concept and Prototype Generation
• Product Registration
• Product Design
• Further System Development
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Steps in the Product Development Process (Cont.)
• Manufacturing System Design
• Review Packaging and Product
• Marketing Review
• Test Market (Optional)
• Refining of Product Before Major Launch
• Major Launch
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Developing Product Specifications
Market & Product Planning
Product Registration
Concept & Prototype Generation
Packaging Design
Further Formulation Development
Continued
First Part of the Product
Development Process
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Further Formulation Development
Manufacturing System Design
Final Packaging & Formulation Review
Marketing Review
Refining of Product Before Major Launch
Major Launch
Optional Today
Test Marketing/ Pilot Production
Cont.
Post Launch Product
Modifications
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Common problems associated with successfully
commercialising research & development
Market
• Failure of invention to meet market needs
• Small size of target market
• Lower price than expected
• Unable to gain distribution
• Lack of market research
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Common problems associated with successfully
commercialising research & development
Technology Takers
• Lack of willingness of companies to take up technology• Disagreements on terms and conditions of technology
transfer• Perceived complexity of technology and risk• Limited human resources on the part of companies to put
time into implementing the new technology or launching the product
• Not familiar with industry• Financially weak• Returns not attractive enough• High capital expenditure not worth the risk• Limited distribution capability
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Common problems associated with successfully
commercialising research & development
Legal
• Lack of Clear and clean patent ownership
• Government regulations
• Legal costs
• Due diligence and burden of risk
• License exclusivity
• Long period of time for patent grant
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Common problems associated with successfully
commercialising research & development
Institutional • Too many people to deal with at the university or
research institute• Low priority by university administrators to allocate
resources for patents, contract research, consultancy, technology transfer and education services
• High cost of licensing• Post license technical support offered by university• Researcher leaves institution• Researchers too many projects (time constraint)• Lack of expertise in commercialisation unit
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Common problems associated with successfully
commercialising research & development
Technology
• Technology not complete
Other
• Unreliable financial estimates
• Rely on Government grant that never comes
• Poor follow up
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151413121110987654321
$1 Million$500,000$250,000$125,000$64,000$32,000$16,000$8,000$4,000$2,000$1,000$500$300$200$100
Who Wants to be a Entrepreneur?
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A: The Researchers
C: Spin-off company
B: The University
D: Industry
50:50
1413121110987654321
$1 Million$500,000$250,000$125,000$64,000$32,000$16,000$8,000$4,000$2,000$1,000$500$300$200$100
Who should be responsible for
commercialisation?
No Right Answer
15
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The Environment
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University Verses Desired Cluster Culture
University Cluster
Objectives Short-term routine functions
Long term uncertain outcomes
Product Certain & Produced Everyday
Uncertain & Intangible
Structure Mechanistic Organic
Rules Structured Rules & Procedures
Less Structured, based on informality
Leadership Authoritarian/Structured/Centralised
Leadership based on intellect & Knowledge
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Cluster Development is Paramount to Ideation
Factors that Encourage Cluster Development• Strong Science Base Leading research organisations: University departments,
hospitals/medical centres and schools, charities, critical mass of researchers, world leading scientist(s)
• Entrepreneurial Culture Commercial awareness and entrepreneurship in universities and research institutes, role models and recognition of entrepreneurs, second generation entrepreneurs.
• Growing Company Base Thriving spin-out and start up companies, more mature role model companies.
• Ability to Attract Key Staff Critical mass of employment opportunities, image/reputation as biotechnology cluster, attractive place to live.
• Premises and Infrastructure Incubators available close to research institutes, premises with wet labs and flexible leasing arrangements, space to expand, good transport links, motorways, rail, international airport.
• Availability of Finance Venture capitalists, business angels• Business Support Services and Large Companies Specialist business, legal, patent,
recruitment, property advisors, large companies in related sectors (healthcare, agrichemical, chemical, food processing)
• Skilled Workforce Skilled workforce, training courses at all levels.• Effective Networking Shared aspirations to be a cluster: regional trade associations, shared
equipment and infrastructure, frequent collaborations.• Supportive Policy Environment National and sector innovation support policies, proportionate
fiscal and regulatory frameworks, support from RDA’s and other economic development agencies, sympathetic planning authorities.
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Invention
Less than 2% of filed patents are ever commercialised
Does a new invention have consumer benefits or create any competitive advantage?
Can consumers accept the new invention?
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Dispelling the myths about innovation
• Most new products are incremental steps in enhancement, rather than something
completely new (similar to the automobile industry)
• Very few really novel innovations are
ever launched commercially
• Most companies are followers and not
innovators (even the Body Shop)
• Out of 100 new ideas, less than 2 become a commercial reality
•Less than 5% of new products launched
on the market are successful
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Table 6.1. Drucker’s Sources of Innovation
Source Explanation Examples
The unexpected success, failure
or external occurrence
Success of a revolutionary product or the application of technology from one industry to another, sudden or unnoticed demographic changes caused by wars, insurgencies, migration, etc.
Apple computerRapid decline of Proton’s market share
An incongruity between reality as it actually is
and what it ought to be
A change that is already occurring or can be made to occur within an industry. It may be visible to those inside the industry, often overlooked or taken for granted.
Sugar free products and sugar replacements due to concern for healthIncreasing demand for travel and holidays due to increasing incomes and leisure time
Inadequacy of an existing
technology or business process
An improvement in process that makes consumers more satisfied based on an improvement or change in technology.
Caffeine free productsMicrowave ovensMobile phones
Changes in industry or
market structure
New ways and means of undertaking business based on identified opportunities or gradual shifting of the nature of the industry.
Health care industryEducation industry – private education
Perceptual changes
Changes in peoples awareness founded on new knowledge and/or values or growing affluence leading to new fashions and tastes
Leisure and exercise industry aerobics & gyms
Demographic changes
Gradual shift of demographics in population by age, income groups or ethnic groups, etc
Establishment of more retirement homes
New knowledge New knowledge or application of existing theoretical knowledge into an existing industry that can create new products not previously in existence
Video and VCD industryRoboticsBiotechnology
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New Knowledge Innovation is the most risky
Better to focus on other sources of innovation: ie, applications of existing ideas and technologies as new knowledge technology development is extremely long term.
Bright ideas are the riskiest source of innovation and rarely succeed. Receptability is always the problem (look at patents files but never commercialised)
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Products more than 5 years old usually don’t make major
contributions to a company’s revenue
•Technology
•Consumer style change
Companies need Innovation
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0 10 20 30
Length of Life Cycle (Years)
Cosmetics
Toys
Tools
Food Items
Pharmaceuticals
Fifty Years Ago
Today
Figure 6.7. The Product Life Cycle Has Shortened Dramatically Over the Last 50 Years
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Sensors in Agriculture
• Precision Farming • Soil Management• Crop Management• Propagation Management• Tissue Culture• Nutrient Management• Integrated Pest management• Overall Farm/Estate Management
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Sensors in Agriculture (Application view)
• Reduction of crop losses
• Quick analysis to adapt to changes
• Maintain adequate and balanced nutrition
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Sensors in Medicine
• In body DNA/Genetic Sensors
• General health sensors
• Disease detection
• Metabolism monitoring & Control
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Sensors in Industry
• Industrial & Process Control
• Quality Control
• Process monitoring
• DSS (Decision support systems) in process control
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Sensors in Industry (Application view)
• Reduction of losses during processing
• Improved recoveries of extractions
• More efficient recycling procedures
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Sensors in the Environment
• Water & Air Pollution
• Identifying sources of pollution
• Monitoring known sources of pollution
• Environmental audits
• Overall environmental monitoring
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Sensors in the Environment (Application view)
• Improve water and soil conservation
• Improve general environmental wellbeing
• Eco-system reinforcement
• Waste control
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Sensors in the Food Industry
• Process control
• Contaminants
• Toxicity & heavy metals sensing
• Halal & haram sensing
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Conclusions
• Require formation of a positive cluster culture (innovative environment)
• Focus on societies needs• Look at new trends and developments• Imperative to enlist commercial collaboration
from the onset of the R&D process• Understand the value of IP and its potential
applications• Focus on applied/collaborative/consulting• Importance of IDS
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Thank You