inhibition analysis and inhibitor-resistant enzymes

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Page 1: Inhibition Analysis and Inhibitor-resistant Enzymes

© 1963 Nature Publishing Group

Page 2: Inhibition Analysis and Inhibitor-resistant Enzymes

© 1963 Nature Publishing Group

THE OF Vol. 267, No. of 5, pp. for and Inc. U.S.A. Inhibition of … · Inhibition of Tissue Kallikrein by Protein C Inhibitor ... We studied the inhibition of tissue kallikrein by

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The Chk1 inhibitor, SRA737, demonstrates chemical ... and intra-strand ... and inhibition of redox cycling Type I topoisomerase inhibitor Type II inhibitor synergy additivity ... BC,

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Mechanisms of enzyme inhibition Competitive inhibition: the inhibitor (I) binds only to the active site. EI ↔ E + I Non-competitive inhibition: binds to