INFECTION AND IMMUNITYVOLUME 6 * NUMBER 6 * DECEMBER 1972

EDITORIAL BOARD

ERWIN NETER, Editor-in-Chief (1974)State University ofNew York at Buffalo

and Children's Hospital, Buffalo

HERBERT R. MORGAN, Editor (1975)University ofRochester

Rochester, N. Y.

QUENTIN N. MYRVIK, Editor (1973)Wake Forest University,Winston-Salem, N.C.

J. W. SHANDS, JR., Editor (1973)University of Florida,

Gainesville

GUY P. YOUMANS, Editor (1974)Northwestern University,

Chicago, Ill.

James C. Allen (1974)Samuel Baron (1972)Almen L. Barron (1972)Elmer L. Becker (1972)Alan W. Bernheimer (1972)L. Joe Berry (1974)Barry R. Bloom (1972)Peter F. Bonventre (1974)Abraham I. Braude (1974)Glenn S. Bulmer (1974)Charlotte C. Campbell (1974)Wallace A. Clyde, Jr. (1973)Zanvil A. Cohn (1974)Richard Ekstedt (1973)William H. Ewing (1974)Richard S. Farr (1974)William W. Ferguson (1972)Richard A. Finkelstein (1973)Charles W. Fishel (1972)Marvin Fishman (1972)Rolf G. Freter (1973)Herman Friedman (1972)Lorraine Friedman (1974)Hugh Fudenberg (1972)Gerald Goldstein (1974)

Irving Gordon (1972)Leonard Hayflick (1972)Mendel Herzberg (1972)Maurice R. Hilleman (1972)Dexter H. Howard (1973)Milton Huppert (1973)Ernest Jawetz (1972)Arthur G. Johnson (1972)Seymour Klebanoff (1974)Richard M. Krause (1972)Carl Lamanna (1973)Edwin H. Lennette (1972)William McCabe (1974)Charles McCall (1974)Maclyn McCarty (1972)Joseph L. Melnick (1972)Bruce Merchant (1974)Stephan E. Mergenhagen (1972)Kelsey C. Milner (1974)H. J. Muller-Eberhard (1974)George Naff (1974)Abner L. Notkins (1972)Pearay I. Ogra (1974)Philip Y. Paterson (1972)

George C. Poppensiek (1972)Sidney Raffel (1972)Stephen H. Richardson (1973)Noel R. Rose (1974)Wallace P. Rowe (1972)Philip K. Russell (1973)Milton Salton (1974)Dwayne C. Savage (1972)Julius Schachter (1974)Russell W. Schaedler (1972)William F. Scherer (1973)Charles C. Shepard (1974)Hutton D. Slade (1974)Kendall 0. Smith (1973)Sigmund Socransky (1974)John K. Spitznagel (1974)David W. Talmage (1974)Lewis W. Wannamaker (1972)Dennis W. Watson (1972)Lawrence G. Wayne (1972)William 0. Weigle (1972)Russell S. Weiser (1972)Emilio Weiss (1974)Robert W. Wheat (1973)George G. Wright (1974)

ROBERT A. DAY, Managing Editor, 1913 1 St., N. W., Washlington, D.C. 20006

EX OFFICIOR. G. E. MURRAY, President (1972-1973)

DONALD E. SHAY, Secretary

Infection and Immunity, a publication of the American Societyfor Microbiology, 1913 I St., N.W., Washington D.C. 20006, isdevoted to the advancement and dissemination of fundamentalknowledge concerning 1) pathogenic microorganisms and infec-tion, 2) ecology, epidemiology and host factors, and 3) immunol-ogy. Infection and Immunity is published monthly, and the twelvenumbers are divided into two volumes per year. The subscriptionprice is S40 (foreign, $41) per year. Single copies are $4.00 (foreign,$4.25). Members of the American Society for Microbiology may

receive Infection and Immunity as part of their dues. Correspon-dence relating to subscriptions, reprints, defective copies, avail-ability of back issues, lost or late proofs, disposition of submittedmanuscripts, and general editorial matters should be directed to

the ASM Publications Office, 1913 I St., N.W., Washington, D.C.

L. LEON CAMPBELL, Vice-President (1972-1973)

T. J. CARSKI, Treasurer

20006 (area 202 833-9416). Correspondence from ASM membersrelating to membership dues, member subscriptions, changes of ad-dress, incorrect address, incorrect journals, etc., should be directedto the Executive Secretary, American Society for Microbiology,1913 I St., N.W., Washington, D.C. 20006. Published monthly bythe ASM at 428 E. Preston St., Baltimore, Md. 21202.

Second class postage paid at Baltimore, Md., and at additionalmailing offices.Made in the United States of America.Copyright © 1972, American Society for Microbiology.All Rights Reserved.

INFECTION AND IMMUNITY, Dec. 1972, p. i-iiiCopyright ©) 1972 American Society for Microbiology

AUTHOR INDEX

VOLUME 6

Abrams, Gerald D., 119Actor, Paul, 156, 886Affronti, Lewis F., 564Agarwal, S. C., 17Akers, T. G., 398Allen, Lois B., 819Antanavage, Joanne, 636Anziano, Dante F., 860, 905Apicella, Michael A., 773Arai, H., 899Argaman, Meir, 651Arstila, Pertti P., 824Artenstein, M. S., 835Atchison, Robert W., 952Avila, F. R., 9Azuma, Ichiro, 414

Babudieri, B., 77Baker, M. B., 465Baker, R. E., 258, 465Balish, Edward, 112Baskerville, A., 83Beam, Walter E., Jr., 282Beasley, R. Palmer, 431Bell, E. John, 232Bergman, Rune, 174Bergner-Rabinowitz, S., 459Bernheimer, Alan W., 636Berry, L. Joe, 97, 766, 883, 886Bigley, Nancy J., 377, 384, 390Blacklow, Neil R., 958Blanden, R. V., 695Bogaerts, W. J. C., 508, 513Bohl, Edward H., 289, 600Bonacorsa, C. M., 425Bonventre, Peter F., 418Boroff, Daniel A., 1003Borsos, Tibor, 648Bowman Saelinger, Catharine,

418Boyde, A., 68Branche, Robert, 324, 699Brandt, Brenda L., 657Brandt, Walter E., 206Brenner, Don J., 308Brown, Albert T., 422Buhles, W. C., 398Bulmer, Glenn S., 199Bulmer, G. S., 162Burgdorfer, Willy, 736

Calnek, B. W., 193Campbell, B. J., 682Carlisle, Harold N., 149

Carllson, Hans E., 703Carmichael, L. E., 348Carp, Richard I., 370, 793Carter, Philip B., 451

Chang, Ik Chin, 92Chapman, S. Stephen, 127, 674Check, Jerome H., 95Chermann, J.-C., 27Cherniak, Robert, 32Chesbro, William, 1028Cho, Gloria J., 689Cho, Han C., 483Clark, H F., 988Cochran, Kenneth W., 819Cockerell, G. L., 266Coggins, Leroy, 416Cole, Robert L., 232Cole, Roger M., 403Collins, Frank M., 451Cooper, M. Robert, 211Cornesky, Robert A., 952Crabbs, C. L., 339Crawford, T. B., 610Cross, William R., 1025Cutler, Jim E., 616

Dajani, Adnan S., 913Dalmasso, Agustin P., 860, 905Darwish, Riad Z., 880Das Gupta, Bibhuti R., 587Davies, John A., 282Davies, M., 909Davis, Charles P., 184DeChatelet, Lawrence R., 211,

302, 982De Clercq, Erik, 344De Haller, R., 38Deibel, R. H., 178De Rizzo, Edda, 335De Somer, Pierre, 344Dickerman, R. W., 425Digeon, M., 27Doggett, R. G., 628, 889Dolin, Raphael, 958Duncan, Charles L., 662Duncan, James L., 689Durville-Van Der Oord, B. J.,

508, 513

Eckert, Herbert L., 730

Fanning, G. R., 308Farber, P. A., 272Farhi, F., 162Farr, Richard S., 574Feeley, J. C., 739Fenje, Paul, 483Ferrieri, Patricia, 913Finkelstein, Richard A., 934Fong, C. K. Y., 865Foo, M. C., 525Forlines, M. E., 739

Formal, S. G., 104Forsgren, Arne, 583Forsum, Urban, 583Foy, Hjordis M., 431Franson, Richard C., 982Franzl, Robert E., 469Frasch, Carl E., 127, 674Freter, R., 134Freter, Rolf, 119, 965Friedman, Lorraine, 616Fubara, Ernest S., 965Fuscaldo, Kathryn E., 95

Gabliks, Janis B., 364Ganguly, N. K., 17Ganguly, Rama, 58Gay, F. W., 83Gemski, P., Jr., 104Gibbons, Ronald J., 723, 852Ginsburg, 1., 459Glasgow, Lowell A., 272, 743Glick, Alan D., 403Goldstein, E., 398Goilmar, Ylva, 240Goodwin, K., 889Goore, Moshe Y., 886Gotschlich, Emil C., 651Gottshall, R. Y., 92Grays, R., 50Green, A. E., 50Gregory, Barry, 156Grunspan, Ruth, 58Gupta, R. K. Paul, 289, 600Guze, L. B., 330

Hahon, Nicholas, 730Hammarstrom, Sten, 703Hammon, William McD., 952Handzel, Zeev T., 651Harrison, G. M., 628Henderson, Bernice G., 32Hentges, David J., 168Herzog, J., 38Hildebrandt, Paul K., 226Hill, W. E., 258Hjelm, Eva, 583Hoffmann, Edward M., 945Hoglund, Stefan, 1003Hong, Richard, 112Hsiung, G. D., 865Hubert, E. G., 330Huggett, David O., 996Huxsoll, David L., 226

Jackson, Anne L., 545Jensen, Ronald, 156Johnson, Mary K., 755Jones, G. W., 918

Vol. 6, No. 6Printed in U.S.A.

AUTHOR INDEX

Kalmanson, G. M., 330Kapral, F. A., 561, 877Karim, R., 465Kasper, D. L., 835Kato, M., 5Kenny, George E., 431Kim, Kwang Shin, 636Kim, Kwang Soo, 793Knox, K. W., 43Kochan, Ivan, 142Kouznetzova, B., 27Krahenbuhl, James L., 829Krall, Judith, 326Kreier, Julius P., 62Kronvall, Goran, 316

Larson, C. L., 258, 465LaRue, Michael K., 934Lee, Adrian, 525Lee, Helen H., 427Leffell, Mary S., 761Lehrer, Samuel, 928Lelchuk, Rosalia, 860Lennette, Edwin H., 1Levin, R. E., 889Licursi, Pamela C., 370Liljemark, W. F., 852Lindberg, Alf A., 703Loos, G. Michael, 648LoSpaluto, Joseph J., 934Luckey, T. D., 682

McCall, Charles E., 211, 302, 982McCallum, R. E., 883McClatchy, J. Kenneth, 574McCloskey, Richard V., 21McCormick, David P., 282McCormick, Kenneth J., 218McCown, Jack M., 277McGuire, T. C., 610McKee, Albert P., 996McVicar, J. W., 718Maguire, M. E., 83Maier, Bruce R., 168Maier, T., 438Makemson, John C., 880Makinodan, T., 518Maloney, Peter C., 657Mansfield, John M., 62Mantyjarvi, Rauno A., 824Margolis, Jeffrey M., 390Mayer, H., 533, 540Mellbye, Ove J., 316Melnick, Joseph L., 335, 557Mendenhall, Joy W., 829Mendiola, L. R., 27Merz, George S., 370Merz, Patricia A., 370Metcalf, Robert H., 178Meurman, Olli H., 824Mifuchi, Ichiji, 414Miller, C. E., 739Miller, Margaret M., 561, 877Milner, Kelsey C., 616

Mims, C. A., 695Minden, Percy, 574Miwatani, Toshio, 1031Moehring, J. M., 487, 493Moehring, T. J., 487, 493Moheimani, Mohammad, 149Montgomerie, J. Z., 330Moore, V. L., 5Morein, Bror, 174Morikawa, Kazuo, 893Much, David H., 1019Mukasa, H., 810Mulcahy, D., 184Mumford, David M., 218Munoz, John J., 232Myerowitz, Richard L., 651Myrvik, Q. N., 5

Nakajima, Hideo, 416Nakamura, Mitsuru, 1025Naylor, James, 156Neter, E., 533, 540Newman, L. W., 50Nicolet, J., 38Norcross, Neil, 416Norrby, Erling, 240, 248Nowotny, Alois, 928Nyberg, Sverker, 1003Nyindo, M. B. A., 226

Oels, H. C., 438Ofek, I., 459Okuyama, Harue, 893Olquin, M. V. Fernando, 289O'Neill, Elizabeth A., 95O'Neill, Karen E., 95Ormsbee, Richard A., 5500rskov, F., 3080rskov, I., 3080ttolenghi-Nightingale, Elena,

785

Pandey, Ramayan, 335Panelius, Martin, 248Patterson, Constance E., 422Peacock, Marius, 232, 550Pederson, Carl E., Jr., 779Pellis, Neal R., 142Perkins, E. H., 518Pfau, C. J., 444Pfohl, Dawn G., 142Pitkin, Donald, 886Pollard, Morris, 255Powanda, M. C., 266Price, J. Townley, 199Pruul, H., 709Pulkkinen, Andrea J., 723

Qualliotine, Diane, 211

Ranhand, Jon M., 403Raynaud, M., 27Reed, Sylvia E., 68

Reich, Melvin, 564Remington, Jack S., 829Remsen, Charles C., 636Reno, Paul W., 945Renoux, Gerard, 324, 699Renoux, Micheline, 699Reynolds, B. L., 709Righthand, Fay, 805Rippe, Delfin F., 97, 766Ristic, Miodrag, 226Robbins, John B., 651Roberto, Ronald R., 1Roberts, Dianna B., 564Robey, G., 682Robinson, David M., 779Robinson, John A., 773Rodriguez, Jose E., 996Russell, Philip K., 206, 277Rutter, J. M., 918

Saif, Linda J., 289, 600Sakurai, Jun, 1031Salmi, Aimo A., 248Saslaw, Samuel, 149Sather, Gladys E., 952Sato, Y., 899Savage, D. C., 184Schmidt, G., 533, 540Schmidt, Nathalie J., 1Schneerson, Rachel, 651Schneider, Herman, 657Schultz, R. M., 9, 591Scott, Robert McNair, 277Seibert, Charlene, 518Sereno, Mitzi M., 958Shapiro, Daniel, 206Sharon, Nehama, 255Sheagren, John N., 101Sheahan, D. G., 104Shirley, Pamela S., 302Simon, Harvey G., 101Sinoussi, F., 27Slade, H. D., 810Slocum, Donald R., 779Smith, Charles B., 326Smith, Randall A., 377, 384Sparkes, John D., 483Spertzel, R. 0., 339Spitznagel, John K., 761Spruance, Spotswood L., 326Staneck, L. D., 444Stark, Raymond L., 662Steigerwalt, A. G., 308Stenback, Wayne A., 218Stewart, William E., II, 344Stewart-Tull, D. E. S., 909Stringfellow, D. A., 743Sturman, Lawrence S., 501Sugiyama, H., 587Sutmoller, P., 718

Tacker, J. R., 162Taga, Sekiko, 1031Takeda, Yoshifumi, 1031

. .

INFECT. IMMUNITY

AUTHOR INDEX

Takemoto, Kenneth K., 501Takeuchi, A., 184Takeuchi, Akio, 1008Tallent, George, 550Taniyama, Tadayoshi, 414Thomas, David W., 355Tinsley, T. W., 427Tompkins, W. A. F., 9, 591Trent, Dennis, 206Trentin, John J., 218Trowbridge, R. S., 444Tschudi, E. Irene, 905

Ushijima, R. N., 465

van Houte, Johannes, 723Vasquez, Cesar, 860Vaughn, R. E., 339Vedros, N., 398Veltri, B. J., 835

Waite, Moseley, 982Waldman, Robert H., 58Walker, Richard, 1028Wallis, Craig, 335, 557Walters, Curla S., 545Wang, Patsy, 982Wannamaker, Lewis W., 913Wannemacher, R. W., Jr., 266Ward, John R., 326Washington, O., 104Watson, Stanley W., 636Weisinger, Rita M., 226Weiss, Emiho, 50, 355Welsh, R. M., 444Wentworth, Berttina B., 431Wenzel, Richard P., 282Whang, H. Y., 533, 540Whisnant, John K., 651Wicken, A. J., 43

Wike, David A., 550, 736Wiktor, T. J., 988Williams, Ralph C., Jr., 316Wong, K. H., 739Worthington, Michael, 643Wright, E. A., 444Wright, George L., Jr., 564Wyatt, Richard G., 958

Yale, Charles E., 112Yamamura, Yuichi, 414Yanagihara, Yasutake, 414Yoshihara, Akiko, 1031Youmans, Anne S., 748, 798Youmans, Guy P., 748, 798Youngner, Julius S., 646

Zajac, Jhor, 1019Zeller, Jack A., 1008Zollinger, W. D., 835

VOL. 6, 1972 iii

INFECTION AND IMMUNITY, Dec. 1972, p. iv-xCopyright © 1972 American Society for Microbiology

SUBJECT INDEX

VOLUME 6

Acid-fast bacillidelayed hypersensitivity, 258

Activated macrophageskilling of Toxoplasma, 829

Adenovirus diseasenasal secretion protein, 282

Adjuvant activityM. leprae, 909

Alpha toxinglucose repression, 689

Alveolar macrophagemethylprednisolone and BCG-mediated changes,

982Amino acid metabolismpneumococcal sepsis, 266

Amphibian red blood cellsparasite, 77

Anti-B antibodiesphagocytosis of E. coli, 95

Antibodiesmeasles infection, 240

Antibody-reovirus complexes, 996Antibody responses

streptococci, 913transrrissible gastroenteritis virus, 289

Anti-gamma globulinsimmune response, 316

Antigenemiacirculating capsular polysaccharide, 431

Antigenic relationshipequine infectious anemia virus, 416

Antirabies vaccinationantibody and immunoglobulin response, 483

Arbovirus infectionIgM antibody, 277

Arenavirusesmorphological and antigenic similarity, 444

Arginasecanine adenovirus inhibitor, 348

Arrhenius effecthemolysin of V. parahaemolyticus, 1031

Australia antigen determinantsoccurrence and persistence, 1

Autochthonous intestinal microfloraimmunological response, 525

AvesVenezuelan encephalitis virus, 425

A59 virusgrowth, 501

Bacteremiacirculating capsular polysaccharide, 431

Bacterial lipopolysaccharideinterferon production, 646

Bacterial transformationsdetection in man, 785

BCG bacilliplaque-forming cells, 893

BCG-treated rabbitsmethylprednisolone sodium succinate treatment, 982

Besnoitia jellisonirole for activated macrophages, 829

BK virushemagglutination characteristics, 824

Blast cellPFC production, 893

Bordetella pertussisintranasal infection of mice, 92leucocytosis-promoting factor, 899

Bordetella pertussis extractimmune response, 513

Bovine nasal secretionparainfluenza-3 neuraminidase, 174

Bovine respiratory diseaseserological investigations, 38

Bovine serum albumin (methylated)immunogenicity of mycobacterial RNA, 798

Candida albicanstoxic substances, 616

Canine adenovirus inhibitorarginase, 348

Capsular antigensrole in pathogenesis, 773

Capsular polysaccharidesC. perfringens, 32

Catecholaminesbactericidal activity, 211polymorphonuclear leukocytes, 211

Cell surface antigeninfluenza virus, 730

Cell wall complexN. meningitidis, 835

Chagas diseaselymphocyte transformation, 905

Choleravibrios and intestinal surface, 134

Cholera exo-enterotoxindispersing and reducing agents, 934gel filtration and electrophoresis, 934

Chondrostagon haematicumparasite in H. italicus, 77

Chronic pneumoniain rats and mice, 83

Chronic rabies virus infection, 988Circulating capsular polysaccharidepneumococcal pneumonia, 431

Clostridium botulinumneurotoxin activation, 587toxin and hemagglutinin, 1003

Clostridium perfringenscapsular polysaccharides, 32enterotoxin purification, 662Hobbs strains, 32

Colonic epithelial cellspiral-shaped organisms, 1008

iv

Vol. 6, No. 6Printed in U.S.A.

SUBJECT INDEX

Common antigenbiochemical basis of immunogenicity, 540immunogenicity, 533, 540

ComplementHI enhancement, 945immune lysis of T. cruzi, 860phospholipase C, 648polymyxin and gram-negative bacteria, 709

Complement polymyxin synergy, 709Congenital infection

Venezuelan equine encephalomyelitis virus, 339Conversion of germfree mice to normal state

function of bacteria, 119Cord factor

role in allergic granuloma formation, 5Corynebacterium acnes

interferon production, 272Cryptococcus neoformans

intracellular fate, 162tumor induction, 199

Cystic fibrosisP. aeruginosa immune status, 628

Cytophilic macroglobulinS. typhimurium, 390

Cytoplasmic granuleslactoferrin, 761

Cytotoxic antibody responsefibroma tumors, 591

Cytotoxicityprotection against, 364

DDTstaphylococcal enterotoxin B, 364

Delayed hypersensitivityS. typhimurium, 384

Delayed hypersensitivity reactionsacid-fast bacilli, 258

Dengue virus type 2HA and CF antigens, 952urea, 952

Deoxynucleic acid relatednessE. coli strains, 308

Deoxyribonucleic acid inhibitionliver extracts, 427

DeterminantsAustralia antigen, 1y and d, 1

Diarrheak88 antigen, 918

Diethylaminoethyl-dextranimmunogenicity of mycobacterial RNA, 798

Diphtheria toxinKB cells, 487protein synthesis inhibition, 418

Diplococcus pneumoniaeenteric bacteria cross-reactions, 651

Diploid cellsinfection with murine cytomegalovirus, 793

Discontinuous counterimmunoelectrophoresisprotein contaminants, 557

Dispersing agentscholera exo-enterotoxin, 934

Echovirus 6interaction with enhancer, 805

Ehrlichia canisdetection of antibodies to, 226

Encephalomyocarditis virusBordetella pertussis extract, 513immunization of mice, 508, 513interferon hyporeactivity of infection, 743murine defense mechanisms, 398purification, concentration, and inactivation, 508UV-inactivated vaccine, 513

Endotoxinisolation and purification, 928phosphoenolpyruvate carboxykinase activation, 97purification, 27

Endotoxin poisoningactivities of fructose-i, 6-diphosphatase and glucose-

6-phosphatase, 883Enhancer complex

echovirus 6, 805Enteric bacteria

cross-reactive with meningococci, 651Enterobacteriaceaecommon antigen, 533, 540

EnterotoxinC. perfringens type A, 662

Enzyme-linked immunosorbent assayantibodies against Salmonella 0 antigens, 703

Epizootic diarrhea of infant mice viruspurification and characterization, 1019

Equine herpesvirus developmentlight and electron microscopy studies, 865

Equine herpesvirus 82Astudy of development, 865

Equine infectious anemia virusantigenic identity, 416

Equine serumidentification and quantitation, 610

Escherichia colianti-B antiserum, 95K88 antigen, 918L-form induction requirements, 880neonatal diarrhea, 918somatic antigens, 104

Escherichia coli L-formcalcium requirement and magnesium stimula-

tion, 880Escherichia coli lipopolysaccharide

antibody, 545Escherichia coli pyelonephritis

immunization effect, 330Escherichia coli strainsDNA relatedness, 308

Exfoliatinneutralization, 561S. aureus, 561skin lesions on neonatal mice, 877skin lesions on S. aureus-infected mice, 877

Farmer's lungserological investigations, 38

Fibroma tumorscytotoxic antibody, 591

VOL. 6,1972 V

SUBJECT INDEX

Food poisoningC. perfringens enterotoxin, 662

Foot-and-mouth diseaseserum-neutralizing activity, 718

Fructose-1 , 6-diphosphataseendotoxin poisoning, 883

Gastroenteritis viral antibodiesporcine immunoglobulins, 600

Gastrointestinal diseasevirus detection and localization, 958

Glucose repressionalpha toxin formation, 689

Glucose-6-phosphataseendotoxin poisoning, 883

Gnotobiotic miceShigella infections, 168V. cholerae, 739

Gnotobiotic ratsserum proteins, 112

Granuloma formationcord factor, 5

Group A streptococciantibody responses, 913degradation of cell walls, 403

Group B arbovirusesvirion polypeptides, 206

Group 0 antigensimmunological and chemical studies, 810

Group 0 streptococciantigens, 810

Group X antigenN. meniingitidis, 773

HemagglutinationBK virus, 824

Hemagglutination inhibitionenhancement by complement, 945

HemagglutininC. botulinum type A, 1003

Hemolysingroup A streptococci, 459heat effect, 1031V. parahaemolyticus, 1031

HemosiderinM. leprae and M. tuberciltosis, 909

Hepatitis B antigenlab procedure, 335

Herellea vaginicolauptake and killing in mice, 21

Herpesvirus hominis type 2BCG cells, 465infections, 465

Hexitol phosphate dehydrogenaseS. mutans heterogeneity, 422

Hydrolytic enzymesendotoxin isolation and purification, 928

Hydrornantes italicusC. haematicum parasite, 77

Hypersensitivityantibody- and cell-mediated, 62trypanosome antigens, 62

Hyporeactivity of infectioninterferon-inducing agents, 743

Immune lymphocytesantiviral action, 695

Immune lysis mechanismT. cruzi, 860

Immune responseanti-gamma globulins, 316Bordetella pertussis extract, 513RBC immunogens, 469

Immunizationpoly A:U effect, 699

ImmunoassayPEPCK, 766

Immunoelectrophoresistwo-dimensional, 564

Immunofluorescent techniquesviral antigen detection, 958

ImmunogenicitySalmonella vaccines, 451

Immunogensretentention by liver and spleen, 469

Immunoglobulin Grabies vaccine, 483

Immunoglobulin M antibodyarbovirus infection, 277

Immunoglobulinstransmissible gastroenteritis virus, 289

Immunological rejuvenationmodel approach, 518

Immunological responseautochthonous intestinal microflora, 525

Immunosorbent assaysalmonella 0 antigens, 703

Indirect fluorescent antibody testEhrlichia canis, 226

Infectious canine hepatitis virusidentification of inhibitor, 348inhibition of CPE, 427

Influenza viruscell surface antigen, 730hemagglutination inhibition, 945

Interferonbacterial lipopolysaccharide, 646chronic rabies virus infection, 988

Interferon inducershyporeactivity of infection, 743target-organ treatment, 819

Interferon-inducing ribonucleic acidV. cholerae, 886

Interferon productioneffect of C. acnes, 272toxicity of poly (rI) -poly (rC), 344

Interferon systemscrapie agent, 643

Intestinal antibodieslocally synthesized, 965sources, 965systemic mechanisms, 965

Intestinal bacteriaconversion of germfree mice, 119

KB cellsdiphtheria toxin resistance, 487RNA viruses, 493

Vi INFECT. IMMUNITY

SUBJECT INDEX

Keratoconjunctivitisvaccination with mycobacteria, 1025

K88 antigenE. coli, 918neonatal diarrhea, 918

Lactobacilliecology, 723

Lactobacillus planitarumteichoic acids, 43

Lactoferrincytoplasmic granules, 761

L cellsmetabolism of Rickettsia, 50

Leptospira biflexa strain Urawapolysaccharide antigen purification, 414

Leucocytosis-promoting factorB. pertussis, 899purification and characterization, 899

LipopolysaccharideE. coli, 545interferon production, 646

Liver extractsDNA inhibition, 427

L-formsV. cholerae, 17

Lymphocyte transformationChagas disease, 905

Lymphocytic choriomeningitis carrier micex-ray-induced lymphoma, 255

Lymphocytic choriomeningitis virusarenavirus, 444immune lymphocyte antiviral action, 695

Lymphomax-ray-induced, 255

Lysozymegrowth of S. faecium, 178lactoferrin association, 761

Macrophagesimmunity to vaccinia virus, 9natural resistance, 438

Macrophage bactericidal functionactivation of mechanisms, 101

Marek's diseaseeffects of passive antibody, 193pathogenesis, 193

Measles antibodiesmultiple sclerosis, 248subacute sclerosing panencephalitis, 248

Measles infectionantibodies, 240

Membranesinteraction with staphylococcal alpha toxin, 636

Meningococcal cell wall complexisolation and characterization, 835

Meningococcal ribosomespotential immunogens, 355

Methylprednisoloneeffect on BCG immunization, 982

Migration inhibitory factoractivation of macrophage bactericidal mechanisms,

101

Mima polymorphauptake and killing in mice, 21

Mouse lethal infectionstaphylococcal nuclease, 1028

Multiple sclerosismeasles antibodies, 248

Murine coronavirusgrowth, 501

Murine cytomegalovirusabortive infection of human diploid cells, 793

Murine resistanceN. meningitidis, 398

Mycobacterial antigenscharacterization and comparison, 564

Mycobacterial ribonucleic acidpolybasic amines and immunogenicity, 798

Mycobacterium bovisHerpesvirus hominis type 2, 465

Mycobacterium lepraeadjuvant activity, 909hemosiderin, 909

Mycobacterium tuberculosisinfection in syngeneic mice, 748

N-acetylneuraminic acidbovine nasal secretion, 174

Nasal secretion proteinadenovirus disease, 282

Natural resistancesalmonellosis, 438

Neisseria meningitidiscell wall complex, 835enteric bacteria cross-reactions, 651group X antigen, 773injection of ribosomal fraction, 355murine resistance, 398production and degradation of polysaccharide, 657serotype antigen, 674serotyping, 127

Neomycin sulfateimmunogenicity of mycobacterial RNA, 798

Neurotropic diseaseinterferon inducers and target-organ treatment, 819

Neutralizing antibodyinfectious antibody-virus complex, 996

Newcastle disease virussynovial cell cultures, 326

Nicotinamide adenine dinucleotide glycohydrolaseguinea pig leukocytes, 302

Oral cavity streptococciS. miteor distribution and adherence, 852

Oral immunizationS. typhimurium, 58V. cholerae, 17

Oral lactobacilliecology, 723

Oral vaccinesSalmonella, 451

Organ culturesdetection of viral agents, 958

Papovavirus groupBK virus as a new candidate, 824

.iiVOL. 6, 1972

SUBJECT INDEX

Parainfluenza-3 neuraminidasebovine nasal secretion, 174

Parainfluenza virusbovine tracheal epithelium, 68

Parana virusarenavirus, 444

Passive antibodyMarek's disease virus, 193

PhagocytosisC. neoformans, 162streptolysins, 459

Phosphoenolpyruvate carboxykinaseactivation by tryptophan, 97inhibition of induction, 766

Phospholipase Caction on complement, 648

PhytohemagglutininChagas disease, 905

Plague-forming cellsBCG-immunized rabbits, 893blast cells, 893

Plaque variantsVEE virus, 779

Pneumococcal hemolysinpurified preparation, 755

Pneumococcal isolatescompetence, 785

Pneumococcal pneumoniaantigenemia and bacteremia, 431

Pneumococcal sepsisamino acid metabolism, 266

Pneumoniain rats and mice, 83

Polyadenylic: polyuridylic complexantibacterial vaccination stimulation, 699rabies vaccine stimulation, 324

Polybasic aminesimmunogenicity of mycobacterial RNA, 798

Polyelectrolyte 60hepatitis B antigen, 335

Polyethylene glycolhepatitis B antigen, 335

Polyinosinic-polycytidylic acidscrapie, 643

Polymorphonuclear leukocytesbactericidal activity, 211catecholamines, 211lactoferrin, 761NAD glycohydrolase, 302

Polymorphonuclear neutrophilsscrapie-induced changes, 370

Polymyxincomplement and gram-negative bacteria, 709

Polynucleotide sequence relatednesspathogenic E. coli strains, 308

Polyriboinosinic acid-polyribocytidylic acidactivity-to-toxicity ratio, 344

Polysaccharidegroup B meningococcal, 657N. meningitidis, 657

Polysaccharide antigenLeptospiro biflexa, 414

Porcine immunoglobulinsgastroenteritis viral antibodies, 600

Precipitin techniquesextraction of type-specific antigens, 127

Primary chicken embryo plaque assayR. rickettsi, 736

Protamine sulfateimmunogenicity of mycobacterial RNA, 798

ProteaseC. botulinum neurotoxin, 587

Protective immunogensRNA-protein fractions, 377

Protective somatic antigenisolation, 156

Protein Aserum-soft agar technique, 583

Protein contaminant detectiondiscontinuous counterimmunoelectrophoresis, 557

Protein synthesis inhibitiondiphtheria toxin, 418

Pseudomonas aeruginosaautosensitivity to pyocin, 889cystic fibrosis, 628immune status, 628

Pseudomonas infectionsvincristine sulfate, 149

PyelonephritisE. coli, 330

PyocinP. aeruginosa, 889

Rabies vaccinestimulation by poly A:U complex, 324

Rat cecumspiral-shaped microorganisms, 184

Reducing agentscholera exo-enterotoxin, 934

Reovirus type 1homologous neutralizing antibody, 996

Reticuloendothelial systemthymectomized mice, 21

Rhinovirusbovine tracheal epithelium, 68

Ribonucleic acidSK&F 42319, 886

Ribonucleic acid-proteindelayed hypersensitivity, 384protective immunogens, 377S. typhimurium, 377

Ribonucleic acid virusesdiphtheria toxin-resistant KB cells, 493resistance, 493

RibosomesV. cholerae, 156

Rickettsiametabolism in L cells, 50suspending media, 550

Rickettsia rickettsiCE plaque assay, 736isolation technique, 736

Rickettsia typhineutralization of toxin, 232

Rubella virussynovial cell cultures, 326

Salmonella 0 antigensantibody titration, 703

* .i. INFECr. IMUNrry

SUBJECT INDEX

Salmonella sp.purification of endotoxins, 27

Salmonella typhimuriumcomplement polymyxin synergy, 709cytophilic macroglobulin, 390delayed hypersensitivity, 384oral immunization of mice, 58RNA-protein fractions, 377

Salmonella vaccinesimmunogenicity, 451

Salmonellosismacrophages, 438natural resistance, 438

Scanning electron microscopestudies of bovine tracheal epithelium, 68

Scrapie-affected animalspolymorphonuclear neutrophils, 370

Scrapie agentinterferon system, 643

Secretory immunoglobulin Aidentification and quantitation, 610

Sensitization of miceBordetella pertussis, 92

Serodiagnosistropical canine pancytopenia, 226

Serotype antigenN. meningitidis, 674

SerotypesN. meningitidis, 127

Serum-neutralization antibodyrabies vaccine, 483

Serum-neutralizing activityfoot-and-mouth disease, 718

Serum proteinsgnotobiotic rats, 112

Serum-soft agar techniqueprotein A, 583

Shared antigensheterologous bacteria, 574

Sheep red blood cellsantibody, 545

Shigellaexperimental infections, 168

Shigella flexnerieye infection resistance, 1025keratoconjunctivitis, 1025

Shigellaflexneri hybridsE. coil somatic antigens, 104virulence, 104

Shigella infectionsantagonism against, 168

SK&F 42319nonspecific protective action, 886

Skin-test reactionsT. congolense infections, 62

Spiral-shaped organismscolonic epithelial cell, 1008identification, 1008normal rat cecum, 184structural characteristics, 1008

Staphylococcal alpha toxininteraction with erythrocyte membranes, 636

Staphylococcal enterotoxin BDDT, 364

Staphylococcal nucleasedetection, 1028

Staphylococcus aureusalpha toxin, 636, 689exfoliatin and skin lesions, 877exfoliatin neutralization, 561protein A, 583serum-soft agar, 583

Streptococci (group A)antibody responses, 913hemolysins, 459

Streptococci (group 0)antigen studies, 810

Streptococcus faeciumgrowth, 178

Streptococcus miteordistribution and adherence in the oral cavity, 852

Streptococcus mutans strainscomparative studies, 422

Streptolysinsantiphagocytic effects, 459

Streptomycin sulfateimmunogenicity of mycobacterial RNA, 798

Subacute sclerosing panencephalitismeasles antibodies, 248

Suspending mediarickettsiae, 550

Synovial cell culturesNewcastle disease virus and rubella virus, 326

Target-organ treatmentinterferon inducers, 819

Teichoic acidsL. plantarum, 43serological studies, 43

Thymic factorisolation and characterization, 682

ToxicityC. albicans, 616

ToxinC. botulinum type A, 1003

Toxin-neutralizing factorR. typhi, 232

Toxoplasmakilling by macrophages, 829

Transmissible gastroenteritis virusantibody responses, 289

Trehalose-6, 6'-dimycolaterole in allergic granuloma formation, 5

Tropical canine pancytopeniaserological diagnosis, 226

Trypanosoma congolensehypersensitivity responses, 62

Trypanosoma cruzimechanism in immune lysis, 860

Trypanosoma (Schizotrypanum) cruzilymphocyte response, 905

Tryptophanphosphoenolpyruvate carboxykinase activation, 97

Tubercle bacilligrowth, 142

Tuberculosishost-parasite interaction, 748syngeneic C57B1/6 mice, 748

Tumor inductionC. neoformans, 199

Two-dimensional immunoelectrophoresismycobacterial antigens, 564

iXVOL. 6, 1972

x

"Unner Pneumonie"serological investigations, 38

Vaccinespoly A:U action, 699

Vaccinial encephalitistreatment with interferon inducers, 819

Vaccinia virusmacrophage immunity, 9macrophage-virus interaction, 9

Venezuelan encephalitis virusembryonic cell cultures, 425

Venezuelan equine encephalomyelitis virusplaque variants, 779transplacental transmission, 339

Vibrio choleraegnotobiotic mice, 739immunological conversion, 739

SUBJECT INDEX INFECT. IMMUNITY

L-forms, 17oral immunization, 17protection by interferon-inducing RNA, 866

Vibrio cholerae (Ogawa)protective somatic antigen, 156

Vibrio parahaemolyticuscrude hemolysin, 1031

Vibriosassociation with intestinal surface in cholera, 134

Vincristine sulfatePseudomonas infections, 149

Virion polypeptidesgroup B arboviruses, 206

Virus-induced antigeninfluenza virus, 730

Zonal centrifugationpurification of endotoxins, 27