increasing dimensionality using variable-energy ionisation
DESCRIPTION
This presentation was delivered at the 25th Annual Meeting of the British Organic Geochemical Society (BOGS), which Markes was delighted to have sponsored. The meeting was held at the School of Natural Sciences and Psychology at Liverpool John Moores University, UK. The meeting featured presentations from across the field of organic geochemistry, including tracing of soil pollution and petroleum geochemistry. This is an excerpt from the original presentation. The full presentation can be downloaded from the Markes website: http://www.markes.com/Resources/Scientific- publications/Conference-presentations.aspxTRANSCRIPT
Select-eV:
Increasing dimensionality in GC×GC–TOF MS
Laura McGregor
BOGS 2014, 10th July; Liverpool
Outline
• Introduction to the BenchTOF
• Select-eV ion-source technology
– What, why and how?
• Case studies:
– GC×GC–TOF MS of a vacuum oil distillate
– Monitoring bio-accumulative substances
What is the BenchTOF?
• A reflectron time-of-flight mass spectrometer
• Platform-neutral
• Innovative design
Mass spectrometry at Markes
BenchTOF technology
Innovative design
High
accelerating
voltage
Differentially pumped source
and analyser chambers
Direct extraction optimises
sensitivity
Multi-stage reflectron
optimises resolution
Ion source technology
Historically…
Variable-energy electron ionisation
70 eV mass spectrum of p-cymene 14 eV mass spectrum of p-cymene
Water Framework Directive (WFD)
• Lower detection limits
• New monitoring methods and analytical
techniques are now necessary
• Focus is on “priority” substances, but what
about those of emerging concern?
GC×GC–TOF MS with Select-eV
River water extract
BPX5
BP
X50
Emerging contaminants
O
O
O
O
O
P
OO
O
CH3
CH3
70 eV
10 eV
14 eV
12 eV
Match factor = 879
Polycyclic Musks
Galaxolide (HHCB)
Implant extract
PCBs
Chloro-pesticides
Amgard TCMP (flame retardant)
Octocrylene (UV filter)
Tetrabromobenzene
Pharmaceuticals
Oxychlordane
PCB 44
Trans-nonachlor
Summary
• Hassle-free soft ionisation
• Improved sensitivity and selectivity
• Reduced matrix impact
• Lower detection limits
The full presentation can be
downloaded from the
Markes website http://www.markes.com/Resources/Scientific-
publications/Conference-presentations.aspx
