immunotherapy: targeting immune checkpoints
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Immunotherapy: Targeting Immune
Checkpoints
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Key Features: • Accurate: reproducible results with low intra & inter assay variability • High Sensitivity and Specificity • Versatile: broad range of sample types including serum, plasma, tissue, cell culture supernatant • Convenient: No special handling or disposal required
ELISA Kits:
Immune Checkpoint ELISA Kits
Product Name Cat. No. Detection Range Detection MethodCD276 (Human) ELISA Kit K4237 0.781 - 50 ng/ml Sandwich CD28 (Human) ELISA Kit K4171 0.625 - 40 ng/ml Sandwich QuickDetect™ CD40 Ligand (Human) ELISA Kit K4414 18.7 - 600 ng/ml Sandwich CD44 (Human) ELISA Kit K4178 0.156 - 10 ng/ml Sandwich CD80 (Human) ELISA Kit K4172 78 - 5000 pg/ml Sandwich CD86 (Human) ELISA Kit K4175 0.156 - 10 ng/ml Sandwich CTLA4/CD152 (Human) ELISA Kit K4157 0.156 - 10 ng/ml Sandwich ICOS (Human) ELISA Kit K4176 1.23 - 300 ng/ml Sandwich ICOS ligand (Mouse) ELISA Kit K4247 0.156 - 10 ng/ml Sandwich OX40 Ligand / TNFSF4 (Human) ELISA Kit K4174 15.6 - 1000 pg/ml Sandwich OX40/CD134 (Human) ELISA Kit K4173 62.5 - 4000 pg/ml Sandwich PD-1 (Human) ELISA Kit K4153 0.156 - 10 ng/ml Sandwich QuickDetect™ PD-L1/B7-H1 (Human) ELISA Kit K4416 12.5 - 800 ng/ml Sandwich PD-L1/CD274 (Human) ELISA Kit K4155 0.156 - 10 ng/ml Sandwich TNFRSF14/CD258 (Human) ELISA Kit K4236 31.2 - 2000 pg/ml Competitive TNFRSF8/CD30 (Human) ELISA Kit K4182 0.781 - 50 ng/ml Sandwich TNFRSF9/4-1BB (Human) ELISA Kit K4238 31.2 - 2000 pg/ml Sandwich TNFSF18 (Human) ELISA Kit K4235 0.156 - 10 ng/ml Sandwich TNFSF8 (Human) ELISA Kit K4248 7.813 - 500 pg/ml Sandwich
Figure: (A): Standard Curve for CTLA4/CD152 (Human) ELISA Kit (Cat. No. K4157-100) (B): Standard Curve for PD-1 (Human) ELISA Kit (Cat. No. K4153-100)
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Recombinant Proteins:Key Features: • High Purity: greater than 90% by SDS-PAGE and SEC-HPLC • High Activity: validated in functional ELISA • Low Endotoxin: less than 1EU/μg • Human CellExp™: mostly expressed in HEK293 cells • Comprehensive collection: Fc-tagged, His-tagged, Biotinylated and/or tag free
Immune Checkpoint Proteins
Product Name Cat. No. Size Source4-1BB Receptor, human recombinant 4370 100 μg, 1000 μg E.coliHuman CellExp™ 4-1BB Ligand/TNFSF9, human recombinant
9240 10 μg, 25 μg HEK293 cells
Human CellExp™ B7-1/CD80, mouse recombinant P1075 10 μg, 50 μg HEK293 cellsHuman CellExp™ B7-2/CD86, human recombinant 7496 10 μg, 50 μg HEK293 cellsHuman CellExp™ B7-H3/CD276, human recombinant 9239 10 μg, 50 μg HEK293 cellsHuman CellExp™ B7-H3/CD276, mouse recombinant P1073 10 μg, 50 μg HEK293 cellsB7-H4/VTCN1, mouse recombinant P1107 10 μg, 50 μg CHO cellsHuman CellExp™ B7-H5/VISTA, human recombinant 9242 10 μg, 50 μg HEK293 cellsBiotinylated PD-1/PDCD1, human recombinant P1038 10 μg, 50 μg E.coliHuman CellExp™ BTLA, human recombinant 9228 10 μg, 50 μg HEK293 cellsHuman CellExp™ CD155, human recombinant 7462 10 μg, 50 μg HEK293 cellsHuman CellExp™ CD160/BY55, human recombinant 7386 10 μg, 50 μg HEK293 cellsHuman CellExp™ CD172A/SIRP, human recombinant 7506 10 μg, 50 μg HEK293 cellsCD226, human recombinant 7310 100 μg E.coliHuman CellExp™ CD244/2B4/SLAMF4, human recombinant
7374 10 μg, 50 μg HEK293 cells
Human CellExp™ CD27/TNFRSF7, human recombinant 9243 25 μg, 100 μg HEK293 cellsHuman CellExp™ CD273/B7-DC/PD-L2, human recombinant
7369 10 μg, 50 μg HEK293 cells
Figure: The purity of Biotinylated Human Recombinant PD-1 (Cat.No. P1038) was >90% as determined by (A) SDS-PAGE and (B) SECHPLC. (C): Biotinylated Human Recombinant PD-1 is able to bind Human PD-L1 immobilized at 2 μg/ml in functional ELISA (n=3).
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Product Name Cat. No. Size SourceHuman CellExp™ CD28, human recombinant 9237 10 μg, 50 μg HEK293 cellsHuman CellExp™ CD40 Ligand/TNFSF5 Protein, Fc Tag, mouse recombinant P1127 10 μg, 50 μg HEK293 cells
CD40Ligand/TRAP, human recombinant 4014 10 μg, 1000 μg E.coliHuman CellExp™ CD47, human recombinant 7385 10 μg HEK293 cellsHuman CellExp™ CD47, rabbit recombinant P1077 10 μg, 50 μg HEK293 cellsHuman CellExp™ CD47, rat recombinant P1076 10 μg, 50 μg HEK293 cellsHuman CellExp™ CD80, human recombinant 7383 10 μg, 50 μg HEK293 cellsHuman CellExp™ CSF1R/CD115, mouse recombinant, Fc Tag P1079 10 μg, 50 μg HEK293 cells
Human CellExp™ CSF1R/CD115, mouse recombinant P1080 10 μg, 50 μg HEK293 cellsHuman CellExp™ CTLA4/CD152, human recombinant 7476 20 μg, 100 μg HEK293 cellsHuman CellExp™ CTLA-4/CD152, mouse recombinant P1081 10 μg, 50 μg HEK293 cellsHuman CellExp™ EGFRvIII, human recombinant P1082 10 μg HEK293 cellsHuman CellExp™ GITR/TNFRSF18, human recombinant 9231 10 μg, 50 μg HEK293 cellsHuman CellExp™ GITR/TNFRSF18, rhesus macaque recombinant P1083 10 μg, 50 μg HEK293 cells
Human CellExp™ GITR Ligand/TNFSF18 Fc Tag, mouse recombinant P1026 10 μg, 50 μg HEK293 cells
Human CellExp™ Human CD40/TNFRSF5, human recombinant 9230 10 μg, 50 μg HEK293 cells
Human CellExp™ HVEM/TNFRSF14, human recombinant 7466 20 μg, 100 μg HEK293 cellsHuman CellExp™ ICOS/CD278, human recombinant 9238 10 μg, 100 μg HEK293 cellsHuman CellExp™ ICOSLG/B7-H2/CD275, human recombinant 7426 20 μg, 100 μg HEK293 cells
ICOSLG/B7-H2/CD275, mouse recombinant P1106 10 μg, 50 μg HEK293 cellsHuman CellExp™ LAG3/CD223, human recombinant 7278 10 μg, 50 μg HEK293 cellsHuman CellExp™ Latent Activin A/INHBA, human recombinant P1078 10 μg, 50 μg HEK293 cells
Human CellExp™ Latent TGF-beta 1/TGFB1, human recombinant P1088 10 μg HEK293 cells
Human CellExp™ OX40/TNFRSF4/CD134, Fc Tag, rat recombinant P1051 10 μg, 50 μg HEK293 cells
Human CellExp™ OX40/TNFRSF4/CD134, rabbit recombinant P1085 10 μg, 50 μg HEK293 cells
Human CellExp™ OX40 Ligand/TNFSF4, human recombinant 9244 10 μg, 50 μg HEK293 cells
Human CellExp™ PD-1/PDCD1 Protein, mouse recombinant P1086 10 μg, 50 μg HEK293 cells
Human CellExp™ PD-1/PDCD1, C-Fc Tag, human recombinant 7500 10 μg, 50 μg HEK293 cells
Human CellExp™ PD-1/PDCD1, C-Fc Tag, mouse recombinant 7503 10 μg, 50 μg HEK293 cells
Human CellExp™ PD-1/PDCD1, human recombinant 7498 10 μg, 50 μg HEK293 cellsHuman CellExp™ PD-1/PDCD1, mouse recombinant 7499 10 μg, 50 μg HEK293 cellsPD-1/PDCD1, human recombinant P1024 10 μg, 50 μg E.coliHuman CellExp™ PD-L1/CD274/B7-H1, human recombinant 7429 10 μg, 50 μg HEK293 cells
Human CellExp™ PD-L1/CD274/B7-H1, mouse recombinant 7428 10 μg, 50 μg HEK293 cells
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Immune Checkpoint Blocking Antibodies
Immune Checkpoint InhibitorsProduct Name Cat. No. Size PurityPD-1/PD-L1 Inhibitor 1 B1213 5 mg, 25 mg ≥%98PD-1/PD-L1 Inhibitor 2 B1050 5 mg, 25 mg ≥%98
Please visit www.biovision.com for a comprehensive overview on our products.
Product Name Cat. No. Size Host Species Application4-1BBL Antibody 5369 30 μg, 100 μg Rb Hu WB, IHCAnti-OX40L (Oxelumab), Human IgG1 Antibody A1088 200 μg Ms Hu Binding assayBTLA Polyclonal Antibody A1082 50 μg Rb Hu WB, IHC, IFCD137 Polyclonal Antibody A1088 100 μl Rb Hu WB, ELISA, IFCD137/4-1BB Antibody A1087 50 μl Rb Hu, Ms, Rt IHCCD223 (LAG3) Polyclonal Antibody A1067 100 μg Rb Hu, Ms, Rt WB, IHC, IFCD27 Polyclonal Antibody A1074 100 μg Rb Hu WB, FCCD28 Polyclonal Antibody A1076 100 μg Rb Hu WB, ELISACTLA4 Polyclonal Antibody A1083 100 μl Rb Hu WB, IHCGITR/TNFSF18 Monoclonal Antibody A1086 50 μg Ms Hu WBGITR/TNFSF18 Polyclonal Antibody A1085 100 μl Rb Hu WBHVEM/TNFRSF14 Antibody A1084 50 μg Rb Hu, Ms WB, IHC, IFOX40 Antibody 3890 100 μg Rb Rt WBTim-3 Antibody 3808 100 μg Rb Hu WB, IHC
Product Name Cat. No. Size SourcePD-L1/CD274, human recombinant P1023 10 μg, 50 μg E.coliHuman CellExp™ PD-L2/B7-DC, mouse recombinant P1087 10 μg, 50 μg HEK293 cellssCD27 Ligand, human recombinant 7125 10 μg, 50 μg E.coliHuman CellExp™ TIGIT, human recombinant 8015 10 μg HEK293 cellsHuman CellExp™ TIM3/HAVR2 Protein, human recombinant P1002 20 μg, 100 μg HEK293 cells
TIM-4, human recombinant P1108 10 μg, 50 μg CHO cellsHuman CellExp™ TNFRSF4/OX40/CD134, human recombinant 7438 10 μg HEK293 cells
Human CellExp™ VTCN1, human recombinant 7412 10 μg, 50 μg HEK293 cells
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