immunisation in asia-pacific: key progress across the region
DESCRIPTION
New presentation on immunisation in the Asia-Pacific region, including support to pentavalent, pneumococcal, measles, rubella, HPV, Japanese encephalitis, hepatitis B and inactivated polio vaccines, the growing number of manufacturers of Gavi-supported vaccines based in Asia-Pacific, and the increasing co-financing contributions by countries in the region. Despite great progress challenges remain: almost half of the world’s under-immunised children are in Gavi-supported countries in Asia-Pacific.TRANSCRIPT
www.gavi.org
IMMUNISATION IN ASIA-PACIFIC
Transforming health outcomes across the region
October 2014
#reacheverychild
Vaccines work
Gav
i/Luc
For
syth
Pentavalent Pneumococcal
Measles2nd dose
Measles campaign
Measles-rubella
campaign
HPV demonstration
project
IPV Hepatitis B
Approved support as of September 2014
Source: Gavi data as of 30 September 2014.*Approved for introduction grants to introduce rubella vaccine into the routine systems.
Gavi vaccine supportin Asia-Pacific
Pentavalent Pneumococcal
Measles2nd dose
Measles campaign
Measles-rubella
campaign
HPV demonstration
project
IPV Hepatitis B
Total commitmentsto the regionsince 2001:
US$ 2.8 bn
Approved support as of September 2014
Source: Gavi data as of 30 September 2014.*Approved for introduction grants to introduce rubella vaccine into the routine systems.
Gavi vaccine supportin Asia-Pacific
230 million children immunisedin Asia-Pacific
230 MILLIONCHILDREN IMMUNISEDIN ASIA-PACIFIC
With Gavi support, 2001‒2013
Source: Gavi data as of 31 December 2013.
With Gavi support, 2001‒2013
Over 50 million children immunised with pentavalent vaccine in Asia-Pacific
Source: Gavi data as of 31 December 2013
Increasing immunisation coveragein Asia-Pacific
DTP3 coverage* in the WHO Western Pacific and South-East Asia regions, 1980–2013
*Includes coverage with the third dose of DTP-containing vaccines, such as pentavalent vaccine.Source: WHO/UNICEF estimates of national immunisation coverage, July 2014
Japanese encephalitis (JE)in the Asia-Pacific region
Source: WHO (www.who.int/mediacentre/factsheets/fs386/en)
EACH YEAR:
~70,000 CASES
UP TO
20,000DEATHS
UP TO HALF OF SURVIVERS
SUFFER PERMANENTDISABILITY
More than
3 BILLIONPEOPLE
live in JE-endemic countriesin Asia-Pacific
First Japanese encephalitis vaccine for children: Gavi’s response
OCT. 2013:First prequalification of a JE vaccine for children.
First time a Chinesemanufacturer receivesWHO prequalification.
NOV. 2013:Gavi opens window for eligible countries to apply for support for JE campaigns.
Catalytic support: countries must self-finance routine introductions.
Measles and measles-rubella vaccine support in Asia-Pacific
Approved support as of September 2014
Measles2nd dose6 countries
Measles campaign2 countries
Measles-rubella
campaign8 countries
Source: Gavi data as of 30 September 2014.*Approved for introduction grants to introduce rubella vaccine into the routine systems.
Gavi support 2002–2006 catalysed national hepatitis B vaccine programme in China
Age-specific prevalence of hepatitis B infection:
1 to <5 5 to <10 10 to <150
2
4
6
8
10
12
Age groups (years old)
1992 2006
Pre
vale
nce
(%)
Courtesy: Dr Mark Kane. Source: Liang XF, Bi SL, Yang WZ, Wang LD, Cui G, Cui FQ, et al. Evaluation of the Impact of Hepatitis B Vaccination among Children Born Between 1992 and 2005 in China. Journal of Infectious disease, 2009,200(1):39-47. Liang XF, Bi SL, Yang WZ, Wang LD, Cui G, Cui FQ, et al. Epidemiological Serosurvey of Hepatitis B in China - Declining HBV Prevalence due to Hepatitis B Vaccination. Vaccine, 2009, 27:6550–6557.
Asia-Pacific countries increase their co-financing of new vaccines
US$ 67 m
2009–2013 2016–2020 projection
US$ 290 m
Source: Gavi data as of October 2014.
2001
1 SUPPLIERIN ASIA-PACIFIC
Increasing number of suppliers of Gavi-supported vaccines based in Asia-Pacific
Sources: UNICEF Supply Division and WHO list of pre-qualified vaccines, 2014.
2014
Increasing number of suppliers of Gavi-supported vaccines based in Asia-Pacific
* Includes both Gavi suppliers and manufacturers of selected pre-qualified Gavi vaccines.Sources: UNICEF Supply Division and WHO list of pre-qualified vaccines, 2014.
8 SUPPLIERS*IN ASIA-PACIFIC
Seven graduating countries in Asia-Pacific, coverage challenges remain in some
Sources: GAVI Alliance data as of September 2014. WHO/UNICEF Estimates of National Immunisation Coverage, July 2014. Note: India will start graduating in 2015, but the duration is yet to be determined.
2016 2017 2018 2019
Papua New 68% Guinea
Timor-Leste 82%
Indonesia 85%
Kiribati 95%
Sri Lanka 99%Mongolia 98%
Bhutan 97%
Year of independence from GAVI support
100
90
80
70
DT
P3
co
vera
ge
(%
) in
20
13
21.8 MILLIONCHILDREN UNDER-IMMUNISED WITH DTP3*GLOBALLY
* Includes coverage with the third dose of DTP-containing vaccines, such as pentavalent vaccine.
Source: WHO/UNICEF estimates of national immunization coverage, July 2014.
Under-immunised childrenglobally
21.8 MILLIONCHILDREN UNDER-IMMUNISED WITH DTP3*GLOBALLY
* Includes coverage with the third dose of DTP-containing vaccines, such as pentavalent vaccine.
Source: WHO/UNICEF estimates of national immunization coverage, July 2014.
Under-immunised childrenin India
7 MILLIONCHILDREN UNDER-IMMUNISED WITH DTP3*IN INDIA
21.8 MILLIONCHILDREN UNDER-IMMUNISED WITH DTP3*GLOBALLY
7 MILLIONCHILDREN UNDER-IMMUNISED WITH DTP3*IN INDIA
10.1 MILLIONCHILDREN UNDER-IMMUNISED WITH DTP3*IN GAVI-SUPPORTED COUNTRIESIN THE ASIA-PACIFIC REGION
* Includes coverage with the third dose of DTP-containing vaccines, such as pentavalent vaccine.
Source: WHO/UNICEF estimates of national immunization coverage, July 2014.
Nearly half of all under-immunised children are in Gavi-supported countries in Asia-Pacific
www.gavi.org
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#reacheverychild
Vaccines work
Gav
i/Asa
d Z
aidi