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How emerging ecosystems fuel innovation Reinventing life sciences May 31 st , 2015

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Page 1: Ibminnovationlifesciences 150601055911-lva1-app6891

© 2015 IBM CorporationIBM Institute for Business Value1

How emerging ecosystems fuel innovation

Reinventing life sciences

© 2015 IBM CorporationMay 31st, 2015

Page 2: Ibminnovationlifesciences 150601055911-lva1-app6891

© 2015 IBM CorporationIBM Institute for Business Value2

Untamable development cost growth, disruptive technologies, and shifting expectations are among the issues facing life sciences today

Cost to develop new products the traditional

way has risen to levels that inhibit innovation

Emergence of personalized medicine, enabled

by new technologies, forces a convergence of

industry players

Increased focus on treatment outcomes pushes

organizations to prove efficacy of their

products

Pricing pressure from payers and regulatory

reform drives the use of generic products and

biosimilars

Demand from new geographic markets

creates new opportunities and creates new

unique challenges

Drug development costs have risen at a rate

2.43 times the inflation rate since the 1970s

Over last decade, cost to generate a human

genome sequence has fallen from $1 billion to

$3-5 thousand

46% of life sciences executives say that

increased pressure to prove efficacy has a

strong impact on their organizations

Generic drug prescriptions capture 84% of

market share within first year of branded drug

patent expiration

Only 59% of life sciences organizations are

currently working in emerging markets or

planning to in the coming year

Page 3: Ibminnovationlifesciences 150601055911-lva1-app6891

© 2015 IBM CorporationIBM Institute for Business Value3

A recent survey showed that the life sciences industry, once notably innovative, struggles with the speed and effectiveness of innovation

Innovation is…

Innovation: a new idea (product, service or

process) that creates value and can become

a major source of strategic advantage,

economic or personal benefit while

improving treatments for patients

in•no•va•tion \ˌi-nə-ˈvā-shən\ Noun

Origin: Latin, 1548

Derives from the Latin word innovatus,

past participle of innovare, ”to make

changes; do something in a new way,”

from in- + novus—"new“

Innovation = Invention + Execution

“I think that innovation is hampered in the

pharmaceutical sector and we need to do

something about it” - Executive Vice President of

pharmaceutical company

Only 25% of executives in the industry

believes their organization is effective at

generating successful innovations

Page 4: Ibminnovationlifesciences 150601055911-lva1-app6891

© 2015 IBM CorporationIBM Institute for Business Value4

New technologies are driving radical disruption - value chains are fragmenting, industries are converging, and ecosystems emerging

An ecosystem is a complex web of

interdependent enterprises and relationships

aimed to create and allocate business value.

The life sciences ecosystem will span multiple

activities, geographies and industries, including

public and private institutions as well as patients.

Traditional value chains in the life sciences industry

are fragmenting

New entrants from other industries are blurring the

traditional definition of life sciences, for example:

Healthcare: Cleveland Clinic develops medical

devices1

Information technology: Google Ventures investing

heavily in life sciences2

Consumer electronics: Apple develops iWatch and

health apps3

Wearables

Social media

Life Sciences

Healthcare

Information Technology

Consumer Electronics

Generics/

biosimilars

Personalized

Medicine

Page 5: Ibminnovationlifesciences 150601055911-lva1-app6891

© 2015 IBM CorporationIBM Institute for Business Value5

Life sciences ecosystems will be collaborative, open and transcend traditional boundaries

The life sciences ecosystem will be characterized by…

1. Boundary transcendence - the life science ecosystem will be

able to work across traditional industry borders, expand into

new geographic locations, provide novel solutions

2. Openness - organizations will benefit from sharing information,

knowledge and data with other ecosystem participants

3. Collaboration - ecosystem participants will form partnerships

as part of ongoing relationships to discover new treatments and

combination therapies

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© 2015 IBM CorporationIBM Institute for Business Value6

Contract Research

Organization

Organizations will need to develop an operating model which provides the vision for innovation in this new ecosystem

Healthcare

Providers

Pharmaceuticals

Research

Patients

Payers

Academia

Medical TechnologyRetailers

Regulators

Target

Innovation

Model

Strategy

Collaboration

&

Connectivity

Tools

&

Assets

Skills

&

Capabilities

CulturePerformance

Metrics

Organization

&

Governance

Processes

Page 7: Ibminnovationlifesciences 150601055911-lva1-app6891

© 2015 IBM CorporationIBM Institute for Business Value7

Heather Fraser

Global Life Sciences & Healthcare Lead

IBM Institute for Business Value

[email protected]

Anthony Marshall

Strategy Leader

IBM Institute for Business Value

[email protected]

Teri MeleseAssistant Vice Chancellor, Industry Research Alliances

Associate Professor, Medicine and Rady School of Management

UC San Diego

[email protected]

For more information about innovation in life sciences and the target

innovation model, please contact:

Download the paper at

http://www-935.ibm.com/services/us/gbs/thoughtleadership/reinventingls/

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