hypertrophic pyloric stenosis (hps).pptx

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Hypertrophic pyloric stenosis (HPS)

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Hypertrophic pyloric stenosis (HPS)

Hypertrophic pyloric stenosis (HPS)A functional gastric outlet obstruction.Hypertrophy and hyperplasia of the muscular layers of the pylorus. Most common cause of gastric outlet obstruction and the most common surgical cause of vomiting in infants.Common age2-8 weeksRare>6 months.

PathphysiologyDiffuse Hypertrophy and hyper plasia of pyloris.Circular muscle hypertrophy.EtiologyUnknownHypergasrinemia. Prostaglandins Nitric oxide.Abnormalities in Myenteric plexus innervation.

Association: Esophageal Atresia & Malrotation(5%).DiagnosisNon bilious projectile Vomiting.Hynger child.Weight Loss.Dehydration.Lethargic.Altered Bowel Habits.Physical ExaminationVisible perstalsis after feeding.Palpable mass in epigatrium.Investigations Biochemical workupHypochloremic hypokalemic hyponatremic metabolic alkalosis.ImagingPlain XrayDilated StomachUltrasound90-100% sensitiveMuscle thickness> 4mmPyloric length>15mmPyloric diameter>10mm

Upper GI StudyString sign.Shoulder sign.

Differential DiagnosisGastroesophageal Reflux.Gastroenteritis.Pyloric Atresia.Amtral web.Duodenal Atresia.Malrotaion.CNS LesionPyloric spasm ICPMetabolic Disorders.

ManagementSurgery is not emergency.Initial stabilizationCorrect eletcrolytes imbalance.Corect dehydration.Adequat urin output (1ml/kg/hour)Surgical Treatment